Professor & Director, Institute of Immunology

Zhigang Tian, M.D., Ph.D. Professor & Director, Institute of Immunology Dean, School of Life Sciences University of Science & Technology of China 443 Huangshan Street, Hefei City, Anhui 230027, P.R.China Tel:(551) 360-0845 ; 360-7379 (Sectarian); 3607377(Lab) Fax: (551) 360-6783; E.mail: [email protected];

Education and Appointment 05/2001–present: Professor, Univ Sci Tech China, China 04/1989-05/2001: Assist/Asso/Full Professor, Shandong Acad Med Sci, China 03/1986-03/1989: Ph.D., Immunology, Normal Bethune Med Univ, China. 03/1983-08/1985: M.S.,Immunol,Shandong Acad Med Sci, China 03/1978-12/1982: M.D., Shanxi Medical University, China

05/2002–04/2003: Visiting Professor, Kanazawa Univ Cancer Inst, Japan 1/2002–4/2002, Visiting Scientist, NIAAA, NIH, USA 2/1999–8/1999: Visiting Professor, Med College Virginia, Richmond, USA 8/1994-6/1996: Visiting Scientist, NCI, NIH, USA

Academic Activity Vice-President, Chinese Society of Immunology (CSI) (2005-2015) Chairman, Organization of Tumor Immunology and Biotherapy, CSI (2006-2015) Excecutive Editor-in-Chief, Cellular & Molecular Immunology (Official Journal of CSI) Editorial Board Member, Journal of Autoimmunity (2010-present) Editorial Board Member, Hepatology (2011-present) Associate Editor-in-Chief, Cytokine (2011-present) Associate Editor-in-Chief, Chinese Science Bulletin (2010-present)

Speciality & Research Field of Interest NK cells, liver immunology and major diseases (cancer, infection and autoimmunity)

Selective Publications

1． Han Q, Zhang C, Zhang J, Tian ZG. Reverse of HBV-induced immune tolerance by an immunostimulatory 3p-HBx-siRNA in a RIG-I-dependent manner. Hepatology, 2011, 54(4):1179-89

2． Jin Z, Sun R, Wei H, Gao X, Chen Y, Tian ZG. Accelerated liver fibrosis in hepatitis B virus transgenic mice: Involvement of natural killer T cells. Hepatology. 2011; 53:219-29.

1 3． Hou X, Zhou R, Wei H, Sun R, Tian ZG. NKG2D-retinoic acid early inducible-1 recognition between natural killer cells and kupffer cells in a novel murine natural killer cell-dependent fulminant hepatitis. Hepatology 2009, 49:940-9.

4． Chen QF, Wei HM, Sun R, Zhang J, Tian ZG. Therapeutic RNA silencing of Cys-X3-Cys chemokine ligand 1 gene prevents mice from adenovirus vector-induced acute liver injury. Hepatology 2008, 47:648-58.

5． Chen Y, Wei H, Sun R, Dong Z, Zhang J, Tian ZG. Increased susceptibility to liver injury in hepatitis B virus transgenic mice involves NKG2D-ligand interaction and natural killer cells. Hepatology. 2007;46(3):706-15.