Name: Annie N. Simpson Birth Date: on File

CURICULUM VITAE

Name: Annie N. Simpson Birth Date: On File Social Security #: On File Home Address: On File Phone: On File Office Address: 135 Cannon Street Charleston, SC 29425 Phone: 843-792-4328 Citizenship and/or Visa Information: US Citizen

Education (Beginning with Baccalaureate Degree): Institution/Location Years Degree/Date (Mo/Yr) Field of Study North Carolina State University, Raleigh NC1993-1998 BS (5/98) Statistics The University of York, York, England 2001-2002 MSc (10/02) Computer Science –Info. Processing Medical University of South Carolina 2008- PhD (Expected 08/13) Health Rehab Science - HSR

Faculty Appointments (Begin with initial appointment): Years Rank Institution Department 2003- Faculty Research Associate MUSC Medicine, Div. Biostatistics and Epidemiology

Other Experience: Years Position Institution Department

2002-2003 Manager PPD Development Clinical Data Management 1999-2001 Data Manager MUSC The Clinical Innovation Group 1999-1999 Statistical and Research Analyst MUSC Center for Health Care Research 1998-1999 Technology Analyst Andersen Consulting 1997-1997 Statistical Programming Intern PPD Pharmaco

Membership in professional/scientific societies (include offices held): 1999 - 2004 Member, Drug Information Association (DIA) 2000 - 2002 Member, Society for Clinical Data Management (SCDA) 2005 - 2009 International Society for Pharmacoeconomics and Outcomes Research (ISPOR) 2008-2009 International Society for Clinical Biostatistics (ICBS) 2003 - Member, American Statistical Association (ASA) 2004 - SAS Users Group International (SUGI)

Editorial Positions:

Extramural Grants/award amount (current and past): As Principal Investigator (% time) As Co-Investigator (% time) PI: Ziad Nihas, MD Source: Cyberonics, Inc. Role: Co-Investigator (10% time) Title: Modeling the antidepressant properties of VNS in the context of a 12 month placebo controlled study Period: 01/10/2007 – 01/09/2008 Amount: $72,388.26

In a personnel position: PI: Kathleen Brady, MD PhD Source: NIDA NIH, $5, 644, 415 (over five years) Role: Biostatistician (40% time) Title: ORWH: SCOR on sex and gender factors affecting women’s health. Period: 09/01/07 – 09/01/12

 PHS 398/2590 (Rev. 05/01) Page ______Biographical Sketch Format Page  PI: Kathleen Brady, MD PhD Source: NIH Role: Database designer and User support trainer (20% time) Title: CTSA – Informatics Core (REDCap Database) Period: 09/01/09 – 09/01/14

PI: Kathleen Brady, MD PhD Source: NIDA NIH DHHS Role: Biostatistician (20% time) Title: Southestern Node of the Clinical Trials Network Period: 10/01/2000 – 08/31/2010

Awards, Honors, Membership in Honorary Societies:

Member, Rotary Club, Charleston Breakfast 2005 Charleston Jaycees President 2004 Charleston Jaycees Vice President 2001-2002 Rotary International Ambassadorial Scholarship for post-graduate study abroad for one year 1993-1997 Chubb Foundation Academic Scholarship 1998 NCSU Graduating Senior, College of Physical and Mathematical Sciences Leadership Award 1998 Phi Sigma Pi Tripod Award for Leadership, Fellowship, Scholarship Mu Sigma Rho Statistics Honor Society NCSU Statistics Club Co-President Phi Sigma Pi National Honor Fraternity; Vice President, Athletic Chair Dean’s List

Academic Committee Activities (past 5 years): Social Committee 2004- (Chairperson 2004-2007); Department: Biostatistics Student Recruitment Committee 2007-2009 ; IT Committee, website subsection chairperson 2005-2006; Unmet Needs Committee 2003

Major Teaching Responsibilities (Current): Graduate Studies Education: Introduction to SAS Programming (2 Credit Hours)

Lectures and Presentations during the last 3 years – Identify the name and location of the meeting/conference. List presentations under the following headings: Invited lectures and presentations: Introduction to Regression. Invited lecture, College of Health Professions , 06/07/2007 3:30pm-4:50pm; MUSC Department of Health Administration and Policy Executive MHA Decision Analysis class. Using n-Query to Calculate Power and Sample Size. 03/11/2008 9:00am-10:00am; MUSC Department of Clinical Neurosciences Drug Addiction Resident Training (DART) Program. Data Collection and Storage Implications in Clinical Studies. 03/24/09 9:00am-10:00am; MUSC Department of Clinical Neurosciences Drug Addiction Resident Training (DART) Program. Data Collection and Storage Implications in Clinical Studies. 04/22/10 1:00pm-2:00pm; MUSC Department of Clinical Neurosciences Drug Addiction Resident Training (DART) Program.

Community Service: Habitat for Humanity Volunteer Crisis Ministries Homeless Shelter Volunteer Camp Happy Days and Special Times JASPCA Jaycee Camp Hope

 PHS 398/2590 (Rev. 05/01) Page ______Biographical Sketch Format Page  Ronald McDonald House Lowcountry AIDS Dining with Friends Carolina Youth Development Center

Publications: Number and list in chronological order publications under the following headings in the order shown. Peer Reviewed Journal Articles: Published or accepted for publication in final form

1. Back SE, Waldrop AE, Saladin ME, Yeatts SD, Simpson A, McRae AL, Upadhyaya HP, Sisson RC, Spratt EG, Allen J, Kreek MJ, Brady KT. Effects of Gender and Cigarette Smoking on Reactivity to Psychological and Pharmacological Stress Provocation. Psychoneuroendocrinology (March 2008) 33, 560-568.

2. Brady KT, McRae AL, Moran-Santa Maria MM, DeSantis SM, Simpson AN, Waldrop AE, Back SE, Kreek MJ. Response to Corticotropin-Releasing Hormone Infusion in Cocaine- Dependent Individuals. Archives of General Psychiatry (April 2009) 66, 422-430.

3. Daniel R, Bourne R, Simpson A, O’Rourke K, Bolster M. Predictors of Response to anti-TNF- alpha Therapies in Rheumatoid Arthritis. American Journal of Pharmacy Benefits. (June 2009) 1(2): 81-88.

4. Williams N, Simpson AN, Simpson KN, Nahas Z. Relapse rates with long term antidepressant drug therapy: A meta-analysis. Journal of Human Psychopharmacology. (July 2009) 24(5):401-8.

5. Spratt, EG., Back, SE., Yeatts, SD., Simpson, AN., McRae-Clark, A., Moran-Santa Maria, MM., Price, KL., Hartwell, KT., Brady, KT. Relationship between Child Abuse and Adult Smoking. International Journal of Psychiatry in Medicine. (Nov. 2009) 39, 417-426.

6. Tolliver, BK., McRae-Clark, AL., Saladin, M., Price, KL., Simpson, AN., DeSantis, SM., Baker, NL., Brady, KT. Determinants of Cue-Elicited Craving and Physiologic Reactivity in Methamphetamine-Dependent Subjects in the Laboratory. (March 2010): 36(2): 106-13. American Journal of Drug and Alcohol Abuse.

7. Waldrop, A. E., Price, K. L., DeSantis, S. M., Simpson, A. N., Back, S. E., McRae, A. L., Spratt, E. G., Kreek, M. J., Brady, K. T. (July 2010). Community-dwelling cocaine-dependent men and women respond differently to social stressors versus cocaine cues. Psychoneuroendocrinology. PMCID: PMC2875320.

8. Moran-Santa Maria, M., McRae-Clark, AL., Back, SE., DeSantis, SM., Baker, NL., Spratt, EG., Simpson, AN., Brady, KT. (Article In Press). Influence of Cocaine Dependence and Early Life Stress on Pituitary-Adrenal Axis Responses to CRH and the Trier Social Stressor. Psychoneuroendocrinology.

9. Back, SE., Payne, RA., Simpson, AN., Brady, KT. Gender and Prescription Opiods: Findings from the National Survey on Drug Use and Health Addictive Behaviors. (Re-submitted with revisions, Journal of Addictive Behaviors).

 PHS 398/2590 (Rev. 05/01) Page ______Biographical Sketch Format Page 