Anti-Kell (Aa 213-243) Polyclonal Antibody (DBGA- 0201) This Product Is for Research Use Only and Is Not Intended for Diagnostic Use

Anti-Kell (aa 213-243) polyclonal antibody (DBGA- 0201) This product is for research use only and is not intended for diagnostic use.

PRODUCT INFORMATION

Product Overview Rabbit polyclonal to Blood Group Kell Antigen

Antigen Description The Kell antigen system (also known as Kell-Cellano system) is a group of antigens on the human red blood cell surface which are important determinants of blood type and are targets for autoimmune or alloimmune diseases which destroy red blood cells. Kell can be noted as K, k, or Kp. The Kell antigens are peptides found within the Kell protein, a 93 kilodalton transmembrane zinc-dependent endopeptidase which is responsible for cleaving endothelin-3.

Target Kell

Immunogen Synthetic peptide conjugated to KLH, corresponding to a region within internal sequence amino acids 213-243 of Human Blood Group Kell Antigen (NP_000411.1).

Isotype IgG

Source/Host Rabbit

Species Reactivity Human

Purification Immunogen affinity purified Notes: DBGA-0201 was purified through a protein A column, followed by peptide affinity purification.

Conjugate Unconjugated

Applications WB

Sequence Similarities Belongs to the peptidase M13 family.

Cellular Localization Cell membrane. Spans the erythrocyte membrane, and is attached to the underlying cytoskeleton.

Positive Control K562 cell lysate.

Procedure Blood Group Antibodies

Format Liquid

Concentration 400 μl at 0.25 mg/ml

45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected]

Buffer 99% PBS

Preservative 0.09% Sodium Azide

Storage Store at 4°C (up to 6 months). For long term storage store at -20°C

45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected]