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CHILDREN’S GASTROENTEROLOGY, , AND NUTRITION CONSULT AND REFERRAL GUIDELINES FOR COMMON GI PROBLEMS

DIAGNOSIS/SYMPTOM SUGGESTIONS FOR POSSIBLE PRE-REFERRAL CONSIDER INITIAL WORK-UP REFERRAL WHEN

CHRONIC ICD-9 code – 789.0 • Weight and height percentiles • Treatment of , If symptoms persist after Age: toddler to adolescence • Urinanalysis if present improvement of stooling • CBC with dif ESR or CRP • Acid suppression - H2 receptor pattern, trial of a lactose-free • Stool Studies: • Antagonist or proton pump diet and lack of response – guaiac • Inhibitor to acid suppression, referral – consider EIA antigen for giardia • Trial off lactose should be made. The child • Careful evaluation of stooling pattern may require • Diary to look for possible triggers such as foods, (EGD) and/or . activities or stressors

CHRONIC, NON-BLOODY ICD-9 code – 787.91 • Weight and height percentiles • Treat any dietary abnormality If Symptoms persist, referral Age: preschool to adolescence • Stool studies: (e.g. high fructose and/or low fat) should be made. The child – guaiac • Try increased fiber in diet may require EGD and/or – consider leukocytes • Diary of dairy and other food colonoscopy. – culture intake in relation to symptoms – EIA antigen for giardia – C. difficile toxin titer – Reducing substances, pH, – Sudan stain (spot test for fecal fat) • CBC with differential, ESR or CRP • Albumin • Quantitative IgA and anti-tTG Antibody (screen for celiac) • Consider sweat test • Consider upper GI with small bowel follow through • Consider laxative abuse, especially in adolescent females

BLOODY DIARRHEA () ICD-9 code – 556 • Stool studies: If evaluation is negative, food If symptoms persist, referral Age: infancy – guaiac protein is likely. should be made. – culture – consider stool O and P – C. difficile toxin titer for child > 3 months old • CBC with differential • PT and PTT • Albumin

BLOODY DIARRHEA (COLITIS) ICD-9 code – 556 • Stool studies: If evaluation is negative, inflammatory If symptoms persist, referral Age: preschool to adolescence – guaiac bowel is likely. should be made. The child will – culture require EGD and colonoscopy. – and C. difficile toxin titer • CBC with differential • PT and PTT • Albumin • Urinanalysis

BLOOD IN STOOL/RECTAL BLEEDING ICD-9 code – 569.3 • Stool studies: Anal/rectal tear is most likely cause. If symptoms persist, referral Age: infancy – guaiac should be made. – culture – C. difficile toxin titer for child > 3 months old • Assess stool frequency and consistency • CBC with differential • PT and PTT GI_InsertCard 4/24/09 2:03 PM Page 2

DIAGNOSIS/SYMPTOM SUGGESTIONS FOR POSSIBLE PRE-REFERRAL CONSIDER INITIAL WORK-UP THERAPY REFERRAL WHEN

BLOOD IN STOOL/ RECTAL BLEEDING ICD-9 code – 569.3 • Stool studies: Anal/rectal tear is most likely cause. If symptoms persist, Age: preschool to adolescence – guaiac referral should be made. – culture Colonoscopy may be – C. difficile toxin titer required. • Assess stool frequency and consistency • CBC with differential • PT and PTT

GASTROESOPHAGEAL ESOPHAGEAL REFLUX DISEASE (GERD) ICD-9 code – 530.11 • Weight and height evaluation Acid suppression (H2 receptor If symptoms persist, referral Age: infancy to adolescence • Stool guaiac antagonist or proton pump inhibitor). should be made. The child • CBC with differential may require an EGD. • Consider Upper GI series • Refer to “Guidelines for Evaluation and Treatment of Gastroesophageal Reflux in Infants and Children” Journal of Pediatric Gastroenterology and Nutrition. (32)Suppl 2. 2001; S1-S31 • Also available at www.naspghan.org (under “Medical Professionals” - Position Papers)

POOR GROWTH (FAILURE TO THRIVE) ICD-9 code – 783.40 • Caloric intake Increase caloric content of diet. If problems persist, referral Age: infancy to adolescence • 3-day diet diary If breastfed infant, consider should be made. The child • Trial of concentrated calories fortifying pumped breast milk or may require an EGD and/or • Stool Studies: Guaiac, pH, reducing substances, supplementation with formula. colonoscopy. pH, Sudanstain • Urinanalysis • CBC with differential • Serum electrolytes • BUN, creatinine • Albumin • Consider sweat test, quantitative IgA, anti-tTG antibody • Can consider ESR or CRP in a child or adolescent

VOMITING WITH OR WITHOUT ABDOMINAL PAIN ICD-9 code – 787.03 • Use history and physical to evaluate for triggers, Consider trial of acid suppression If problems persist, Age: infancy to adolescence GERD, or neurologic causes (H2 receptor antagonist or proton referral should be made. • Weight and height percentiles pump Inhibitor) The child may require • CBC with differential an EGD. • Serum electrolytes • Amylase and lipase • Consider ESR or CRP • Urinanalysis • Consider upper GI series to rule out anatomic abnormality

CONSTIPATION ICD-9 code – 564.00 Refer to “Constipation in Infants and Children: Treatment should include the AAP If problems persist, Age: infancy to adolescence Evaluation and Treatment” Journal of Pediatric recommended 6 servings of fruits referral should be made. Gastroenterology and Nutrition. 1999:29:612-26. and vegetables each day, adequate Also available at www.naspghan.org (under “Medical fluid intake, daily vigorous physical Professionals” - Position Papers activity and the use of a safe, (prefer- ably non-absorbed) stool softener like lactulose or miralax. Successful treat- ment should continue to ensure that improvement persists.

ENCOPRESIS ICD-9 code – 787.6 See above Successful treatment usually involves If problems persist, Age: preschool to adolescence 3 components: (1) treatment of con- referral should be made. stipation (see above), (2) a regular pattern of sitting on the toilet after each meal to invoke the gastro- reflex, and (3) psychological coun- seling. Successful treatment also usually takes months.