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International Discussion on Specified Risk Materials
INTERNATIONAL DISCUSSION ON SPECIFIED RISK MATERIALS Hosted by the Alberta Prion Research Institute Canmore, Alberta March 25-27, 2015 Specified risk materials (SRM) in cattle carcasses are those tissues in infected animals that contain the vast majority (more than 99%) of infectious prions1. Canada’s definition of SRM is consistent with guidelines of the World Organisation for Animal Health (OIE) apart from tonsils where the OIE recommends that they be excluded from animals of all ages. The list of tissues and the age cut-off defining SRM varies amongst countries (Table 1). The removal of SRM from human food and animal feed has required considerable and costly changes by the cattle and beef industries of many countries. Canada’s beef industry faces an additional challenge as a result of differences between Canada and the United States (US) in the list of tissues excluded from the animal feed chain. Both countries exclude the same list of tissues from the human food supply but not from the animal feed chain (Table 1). The impact of this is additional disposal costs and resulting competiveness issues. Although the US is now a negligible risk country for bovine spongiform encephalopathy (BSE), it continues to exclude SRM from human food (full list) and animal feed (partial list). At the invitation of the Alberta Prion Research Institute, knowledgeable individuals with experience with SRM from industry, government and academia participated in a facilitated discussion about all aspects of SRM. Appendix A contains a list of participants. The participants were invited in their personal capacity and views expressed were not necessarily those of their respective affiliated organizations. -
Bovine Spongiform Encephalopathy (BSE, Or “Mad Cow Disease”) in North America: a Chronology of Selected Events
Order Code RL32932 CRS Report for Congress .Received through the CRS Web Bovine Spongiform Encephalopathy (BSE, or “Mad Cow Disease”) in North America: A Chronology of Selected Events Updated June 28, 2005 Geoffrey S. Becker Specialist in Agricultural Policy Resources, Science, and Industry Division Congressional Research Service ˜ The Library of Congress Bovine Spongiform Encephalopathy (BSE, or “Mad Cow Disease”) in North America: A Chronology of Selected Events Summary This report provides a chronology of selected events leading up to and following the discoveries of bovine spongiform encephalopathy (BSE, or “mad cow disease”) in North America. These are primarily regulatory, legal, and congressional developments that are frequently referenced by policymakers as significant in the ongoing policy debate. The chronology does not contain entries for the introduction of the many BSE-related bills introduced into this or previous Congresses, except for those in recent years where committee or floor action has occurred. This report, which will be updated if significant developments ensue, is intended to be used alongside other CRS reports that provide more background and context for the BSE policy debate, and that cover many specific legislative proposals. The chronology begins in 1986, when BSE was first identified by a British laboratory. As the United Kingdom and others attempted to understand and contain BSE, the U.S. and Canadian governments were establishing panels to study the disease and began instituting a series of safeguards aimed at keeping it out of North America or stopping any spread if it should occur here. The chronology proceeds into May 2003, when Canada reported the first native case in North America; December 2003, when the United States reported finding a case in a U.S. -
Transmissible Spongiform Encephalopathies R: Concise Reviews in Food Science WILL HUESTON, PH.D., D.V.M., and CORY M
JFS R: Concise Reviews/Hypotheses in Food Science Scientific Status Summary Transmissible Spongiform Encephalopathies R: Concise Reviews in Food Science WILL HUESTON, PH.D., D.V.M., AND CORY M. BRYANT, PH.D. The Institute of Food Technologists has issued this Scientific Status Summary to update our knowledge of transmissible spongiform encephalopathies and provide an authoritative perspective on the surrounding regu- latory and trade landscape. Keywords: Scrapie, Chronic Wasting Disease, Bovine Spongiform Encephalopathy, Creutzfeldt-Jakob disease ransmissible spongiform encephalopathies (TSEs) encom- evolving information pertaining to these diseases. This Scientific pass a group of diseases affecting several mammalian spe- Status Summary attempts to capture major findings and trends, Tcies—mink, cats, sheep, goats, cattle, deer, and elk (Figure and we encourage the reader to check for updates, as new research 1)—including humans. These diseases are transmissible because may alter our current understanding. they are capable of being transferred from one animal to another, spongiform because they cause the appearance of sponge-like holes Science Review in the brain of those affected, and encephalopathic because they he first evidence of TSE diagnosis was recorded in Europe in are neurodegenerative diseases of the brain. Tsheep in 1732 (DEFRA 2002), although the disease was not rec- TSEs continue to pose a concern with respect to animal and hu- ognized to be transmissible until 1936 (Cuille and Chelle 1936). man health. This was recently underscored by discovery of bovine TSEs cause brain vacuolation, astrogliosis, neuronal apoptosis, and spongiform encephalopathy (BSE)–positive cattle in Canada and accumulation of misfolded, protease-resistant prion proteins in the the United States and the apparent spread of variant Creutzfeldt- central nervous system (Soto and Castilla 2004). -
Transmissible Spongiform Encephalopathies TSE Management Management at the Slaughterhouse at the Slaughterhouse
39 TRANSMissible SPongiforM ENCEPhaloPathieS TSE management ManageMENT at THE SLAUGHTERHOUSE at the slaughterhouse 1. GENERAL CONCEPTS In the slaughterhouse, TSE management focuses on preventing material containing infectious prion protein from entering the food and feed chains. This is accomplished by identification and removal of BSE suspect cattle, separation and safe disposal of mate- rial potentially containing an infectious agent (specified risk material/[SRM]) and control of cross contamination. In this chapter, only slaughterhouse aspects directly related to control of BSE are included and, in general, procedures are described for larger slaughterhouses. These concepts remain the same for all slaughtering of cattle, but must be adapted for other situations (i.e. when the carcass is not split). Overall good manufacturing practices (GMP) for slaughtering are available from Codex (www.codexalimentarius.net), and are given in the FAO manual Good practices for the meat industry (FAO, 2004). 2. ANIMAL identification To ensure traceability of and to guarantee proper payment for the slaughtered animal, every animal must be identified and carcasses must be trackable through the slaugh- terhouse. Each slaughterhouse decides on its own system, but it must be possible to trace back to the animal’s identity on the farm of origin from each piece of cut meat. 3. ARRIVAL AND ANTE MORTEM EXAMINATION The first point where BSE could possibly be detected is at initial unloading of the ani- mals at the slaughterhouse. It is therefore very important to have cattle inspected as they come off the truck (ante mortem examination) and enter the lairage. At minimum, the cattle should be examined when moving around the lairage. -
Bovine Spongiform Encephalopathy; Importation of Bovines and Bovine Products; Final Rule
Vol. 78 Wednesday, No. 233 December 4, 2013 Part II Department of Agriculture Animal and Plant Health Inspection Service 9 CFR Parts 92, 93, 94, et al. Bovine Spongiform Encephalopathy; Importation of Bovines and Bovine Products; Final Rule VerDate Mar<15>2010 18:50 Dec 03, 2013 Jkt 232001 PO 00000 Frm 00001 Fmt 4717 Sfmt 4717 E:\FR\FM\04DER2.SGM 04DER2 maindgalligan on DSK5TPTVN1PROD with RULES 72980 Federal Register / Vol. 78, No. 233 / Wednesday, December 4, 2013 / Rules and Regulations DEPARTMENT OF AGRICULTURE Center for Import and Export, VS, Summary of the Major Provisions of the APHIS, 4700 River Road, Unit 39, Regulatory Action Animal and Plant Health Inspection Riverdale, MD 20737–1231; 301–851– The current regulations prohibit the Service 3300. importation of live ruminants and most For information regarding ruminant ruminant products from regions that 9 CFR Parts 92, 93, 94, 95, 96, and 98 products and for other information have BSE or that present an undue risk regarding this rule, contact Dr. [Docket No. APHIS–2008–0010] for BSE. The regulations are less Christopher Robinson, Assistant restrictive for ruminants and ruminant RIN 0579–AC68 Director, Technical Trade Services, products from BSE minimal-risk regions Animal Products, National Center for (currently only Canada). Additionally, Bovine Spongiform Encephalopathy; Import and Export, VS, APHIS, 4700 the regulations allow the importation of Importation of Bovines and Bovine River Road, Unit 38, Riverdale, MD boneless beef from Japan even though Products 20737–1231; 301–851–3300. Japan is listed as a region that has BSE. AGENCY: Animal and Plant Health SUPPLEMENTARY INFORMATION: We are replacing the current BSE Inspection Service, USDA. -
Bovine Spongiform Encephalopathy (BSE) Is a Fatal Neurodegenerative Disease, Spongiform Caused by a Prion, That Mainly Affects Cattle
Bovine Importance Bovine spongiform encephalopathy (BSE) is a fatal neurodegenerative disease, Spongiform caused by a prion, that mainly affects cattle. Other ruminants, cats, nonhuman primates and humans are occasionally affected; this disease is called feline Encephalopathy spongiform encephalopathy (FSE) in cats, and variant Creutzfeldt-Jakob disease (vCJD) in people. BSE is primarily acquired by eating prion-containing tissues from Mad Cow Disease, an infected animal. Cooking and standard disinfection procedures do not destroy this BSE agent. Infected animals or people do not become ill for years; however, the disease is always progressive and fatal once clinical signs develop. BSE was first reported in the United Kingdom in the 1980s. Its origins are unknown; however, the recycling of Last Updated: August 2016 ruminant tissues into ruminant feed amplified BSE prions and caused an explosive epidemic in the U.K. This epidemic peaked in 1992, with almost 1,000 new cases diagnosed each week. BSE also spread to many European countries, North America, parts of Asia and possibly other areas of the world. Control measures, including restrictions on ruminant feed, have now greatly decreased its prevalence, and cases have become uncommon or rare in many areas. Many countries have also passed new regulations to prevent BSE-containing tissues from entering human food supplies. As a result of increased surveillance, BSE prions that differ from the prion causing ‘classical’ BSE have been identified at very low levels in cattle populations. The leading hypothesis, at present, is that these atypical prions arise spontaneously in cattle. Some experiments suggest that an atypical prion might have given rise to the BSE epizootic when it was amplified in cattle feed. -
MF2678 the Economic Impact of BSE on the U.S. Beef Industry: Product Value Losses, Regulatory Costs, and Consumer Reactions
5IF&DPOPNJD*NQBDUPG#4& ,BOTBT4UBUF6OJWFSTJUZ POUIF64#FFG*OEVTUSZ "HSJDVMUVSBM&YQFSJNFOU4UBUJPO BOE$PPQFSBUJWF&YUFOTJPO4FSWJDF 1SPEVDU7BMVF-PTTFT 3FHVMBUPSZ $PTUT BOE$POTVNFS3FBDUJPOT Brian Coffey Research Assistant Department of Agricultural Economics James Mintert Professor Department of Agricultural Economics Sean Fox Professor Department of Agricultural Economics Ted Schroeder Professor Department of Agricultural Economics Luc Valentin Research Assistant Department of Agricultural Economics Prepared for The Kansas Department of Agriculture Adrian Polansky, Secretary of Agriculture Acknowledgements We acknowledge funding assistance from the Kansas Department of Agriculture and the U.S. Department of Agriculture Economic Research Service. We are grateful to the numerous beef industry participants who were very generous in providing their time and sharing their expertise with us in this research effort. We also appreciate helpful comments from Dr. Gary Brester and Dr. Dell Allen on an earlier draft of this manuscript. Any remaining errors are the responsibility of the authors. Some cover photos courtesy of USDA Natural Resources Conservation Service. Contents Executive Summary ..............................................................................................3 Background ........................................................................................................................... 3 Regulatory Response to the December 23 Case ....................................................................3 Costs Associated -
Can Composting Solve Specified Risk Material Issues? Shanwei Xu1, Tim Reuter2, Kim Stanford2 and Tim A
What Farmer Educators Need to Know about Mortality Composting – Beyond the Basics Can Composting Solve Specified Risk Material Issues? Shanwei Xu1, Tim Reuter2, Kim Stanford2 and Tim A. McAllister1 1Lethbridge Research Centre, Agriculture and Agri-Food Canada 2Alberta Agriculture and Rural Development, Government of Alberta What Are Specified Risk Materials? Prion diseases, i.e., transmissible spongiform encephalopathies (TSE), are a group of fatal neurodegenera- tive diseases including scrapie in sheep and goats, chronic wasting disease (CWD) in deer and elk, bovine spongiform encephalopathy (BSE) in cattle, and Creutzfeldt-Jakob disease (CJD) in humans. As of February 2014, 19 cases of BSE have been confirmed in Canada and 4 cases in the U.S. The occur- rence of BSE in North America has resulted in over an $11 billion loss to the cattle industry (Le Roy et al., 2006; Coffey et al., 2005). Due to the identification of BSE in Canada in 2003, the Canadian Food Inspection Agency (CFIA) imposed an enhanced feed ban in July of 2007 to prevent the introduction of specified risk materials (SRM; e.g., spinal cord, skull, brain, vertebral column, eyes, tonsils, trigeminal and dorsal root and distal ileum) into the food chain. If these tissues are not removed from the carcass, then the entire carcass is designated as SRM. The U.S. government subsequently passed a similar regulation in 2008. It is estimated that there are 250,000 tonnes of SRM generated in Canada annually with 74,000 tonnes of this originating in the province of Alberta (Gilroyed et al., 2010; AARI, 2005). The cervid industry in Canada is much smaller, but still with 145,000 animals and an overall mortality rate of 5.7% (Canadian Cervid Alliance, 2009; Haigh et al., 2005), it generates significant quantities of SRM. -
Bovine Spongiform Encephalopathy (BSE): Risks and Implications for the United States
Bovine Spongiform Encephalopathy (BSE): Risks and Implications for the United States John A. Fox and Hikaru Hanawa Peterson* Paper presented at the NCR-134 Conference on Applied Commodity Price Analysis, Forecasting, and Market Risk Management St. Louis, Missouri, April 22-23, 2002 Copyright 2002 by John A. Fox and Hikaru Hanawa Peterson. All rights reserved. Readers may make verbatim copies of this document for non-commercial purposes by any means, provided that this copyright notice appears on all such copies. * Fox is associate professor ([email protected]) and Peterson is assistant professor, Department of Agricultural Economics, Kansas State University. Bovine Spongiform Encephalopathy (BSE): Risks and Implications for the United States Practitioner’s Abstract: Mad cow disease has caused two major disruptions in European beef markets—first in the U.K. in 1996 following the announcement of a link to new variant Creutzfeldt-Jacob Disease in humans, and the second in late 2000 following the discovery of “homegrown” cases of the disease in Germany and Spain. In September 2001 the disease was discovered in Japan where it also resulted in an immediate and substantial reduction in beef demand. The disease has not been found in the U.S. but the current scope of detection efforts provides little assurance that it does not exist at a very low level. The U.S. has taken a number of precautionary measures to reduce both the risk of importing the disease and the risk of the disease spreading if it were to appear. Those measures include a ban on the feeding of ruminant protein to ruminants—a measure that the General Accounting Office concluded was not being adequately enforced and which failed to halt the disease in the U.K. -
Biodiesel from Specified Risk Material Tallow: an Appraisal of TSE Risks and Their Reduction
Biodiesel from Specified Risk Material Tallow: An Appraisal of TSE Risks and their Reduction Biodiesel from Specified Risk Material Tallow: An Appraisal of TSE Risks and their Reduction i Acknowledgements Biodiesel from Specified Risk Material Tallow: An Appraisal of TSE Risks and Their Reduction was prepared for the International Energy Agency’s (IEA’s) Executive Committee on Advanced Motor Fuels. The report was supported by agencies in Canada, Finland and the United States through their participation in the IEA’s Implementing Agreement on Advanced Motor Fuels. The authors and ATFCAN gratefully acknowledge the Executive Committee on Advanced Motor Fuels, Natural Resources Canada, the United States Department of Energy and the National Technology Agency of Finland. The views and opinions of the authors expressed in the report do not necessarily state or reflect those of the IEA, nor of any of the participating countries and supporting agencies. 9 Antares Drive, Suite 224 Ottawa, Ontario K2E 7V5 Canada Tel: +1 613 231 4310 Fax: +1 613 231 4353 Email: [email protected] Web: www.atfcan.com ii About the Authors This report was prepared as a collaborative effort by an international team of experts from Canada, Switzerland, the United Kingdom and the United States. Anne-Marie Baribeau, B.A.Sc., M.A.Sc. (Canada) Dr. Ray Bradley, MSc, BVetMed, FRCVS, FRCPath, CBiol, MIBiol. (United Kingdom) Dr. Paul Brown, MD (United States) Dr. James Goodwin, Jr. Ph.D (United States) Dr. Ulrich Kihm, Prof. Dr. med. vet. (Switzerland) Dr. Edgar Lotero, Ph.D (United States) Don O’Connor, B.A.Sc., P.Eng. -
Proposal to Amend the Transmissible Spongiform Encephalopathies (Scotland) Regulations 2010
Proposal to amend the Transmissible Spongiform Encephalopathies (Scotland) Regulations 2010 Consultation Open: 25 February 2019 Close: 11 March 2019 February 2019 Topic This consultation is seeking views on amending the Transmissible Spongiform Encephalopathies (Scotland) Regulations 2010. The following proposed amendments are adopting changes to EU legislation that have already been implemented across the UK on an administrative basis: Removal of the requirement for abattoirs slaughtering cattle that require BSE testing to have a required method of operation (RMOP) Amendment to domestic legislation regarding on-farm controls for classical scrapie Proposal to permit the feeding of pig and poultry processed animal protein to farmed fish Proposal to enable the feed industry to use processed animal protein derived from insects in feed for aquaculture Amend the list of tissues from ruminants (cattle, sheep and goats) that are designated as Specified Risk Material (SRM) to reflect changes to EU legislation Amendment to labelling carcases of bovine vertebral column removal Provide a statutory mechanism by which food business operators can apply for approval to use an alternative method of spinal cord removal, other than carcase splitting, for sheep and goats aged over 12 months of age Clarify wording relating to the removal of SRM from sheep and goats in a slaughterhouse Provide a statutory mechanism to permit the Competent Authority of the Member State of slaughter to approve an alternative method, other than dentition, to determine the age of sheep and goats for SRM removal purposes Proposal to amend the specification of the colouring agent for the staining of SRM Responding to this consultation Please respond to this consultation through email to the email address: [email protected] If you are unable to respond via email, please submit your response through post.