DOCSLIB.ORG

MC HISA Round 1 Peer Review Comments and CDC Responses

Total Page：16

File Type：pdf, Size：1020Kb

Download full-text PDF Read full-text
MC HISA Round 1 Peer Review Comments and CDC Responses 1 Peer Review Comments and CDC Responses for Information for Providers to Share with Male Patients and Parents Regarding Male Circumcision and the Prevention of HIV infection, Sexually Transmitted Infections, and other Health Outcomes* and Background, Methods, and Synthesis of Scientific Information Used to Inform “Information for Providers to Share with Male Patients and Parents Regarding Male Circumcision and the Prevention of HIV Infection, Sexually Transmitted Infections, and other Health Outcomes”** *Formerly titled: Recommendations for Providers Counseling Male Patients and Parents Regarding Male Circumcision and the Prevention of HIV Infection, Sexually Transmitted Infections, and other Health Outcomes **Formerly titled: Background, Methods, and Synthesis of Scientific Information Used to Inform the “Recommendations for Providers Counseling Male Patients and Parents Regarding Male Circumcision and the Prevention of HIV Infection, Sexually Transmitted Infections, and other Health Outcomes.” GENERAL RESPONSE: We thank the peer reviewers for taking the time to review and provide comments regarding the “Recommendations for Providers Counseling Male Patients and Parents Regarding Male Circumcision and the Prevention of HIV Infection, STIs, and other Health Outcomes” and the “Background, Methods, and Synthesis of Scientific Information Used to Inform the ‘Recommendations for Providers Counseling Male Patients and Parents Regarding Male Circumcision and the Prevention of HIV infection, STIs, and other Health Outcomes.” Citations corresponding to reviewer comments are located on pages 154-226. Citations corresponding to CDC responses are located on pages 227-230. The three peer reviewers were professors of internal medicine and pediatrics with expertise in HIV, sexually transmitted infections, and male circumcision. Reviewer No. 1: COMMENT: I have reviewed both documents and agree with the recommendations. I don’t have substantive changes to suggest. Please see the attached for a suggestion about removing two comma splices. RESPONSE: Thanks for taking the time to review the documents. The suggested edits were made to the policy document. Reviewer No. 2: COMMENT: I've reviewed the documents and recommendations, and I find them to be fair, well crafted, and appropriately extensive. I support them in their current form and in their entirety, and I do not have edits to recommend. From the perspective of a practicing urologist, I would say that great benefit will be derived from such a clear statement indicating efficacy not only in potentially preventing HIV but also of other STDs and health conditions likely related to STDs in a care environment that is 2 increasingly limiting. Another great potential benefit to be derived will be in increasing acceptance of male circumcision in a historical era of increasing opposition. RESPONSE: Thanks for taking the time to review the documents and provide comments. Reviewer No. 3: Note from CDC: Reviewer No. 3 has provided three sections of commentary: (1) general comments regarding the CDC recommendations, (2) comments pertaining to specific text of the CDC recommendations, and (3) summary comments about each section of the CDC background document. A response has been provided to each main point in the general comments on the CDC recommendations (1) and to each comment about specific text in the draft recommendations (2). A summary response has been provided at the beginning commentary on the CDC background document (3). Citations pertaining to comments from peer reviewer No. 3 are located on pages 140 – 208. Citations pertaining to responses from CDC are located on pages 209-212. CDC thanks the reviewer for taking the time to review the documents and providing extensive comments. General Comments Regarding CDC Draft Recommendations and Background Documents COMMENT: This peer-review of the Centers for Disease Control and Prevention’s (CDC’s) Draft Recommendations and Background Documents was generated after December 2, 2014 when the documents first became available. Because of the limited time in which to review and comment on these documents, there may be some topics that could have been addressed more completely, some topics that were addressed more than once, and some citations that may be missing. In the interest of time, the citations given in the review may not be sequenced properly, but each citation should be properly identified. There may be some grammatical and typographical errors because there was insufficient time to identify and correct them. The comments addressing the Recommendations draft are made in direct response to the statements in that draft and appear in italics. The evaluation of the Background draft does not use the statement-by- statement format. This is a peer-review of draft documents and the comments are directed at these documents. It may be helpful for the reader to have copies of the drafts available. 3 Several things are remarkable about this draft. First, is the obvious lack of scientific and scholarly rigor that went into preparing this draft. While it is stated that the writers of the draft performed a search of the medical literature, the evidence (in the form of the draft itself) indicates that their search was far from complete. Instead of collecting and analyzing data, they relied on review articles to do the work for them. One review article was published in 1983 — a bit dated to say the least. In some sections, the draft relied on opinion pieces as their sources of information. In areas where review articles were not available, the information provided was far from complete. For example, in reviewing the medical literature on the impact of male circumcision in North America, which is a major thrust of the draft, only two of the eight available studies are mentioned. Similarly, no serious attempt was made to review the harms, risks, complications, or pain associated with male circumcision. The draft has only 255 references, some of which are redundant, which are only a small sampling of the material available in the literature. A PUBMED search using the search word “circumcision” on January 12, 2015 identified 6338 publications. RESPONSE 1: The CDC background document summarizes findings from a systematic literature review that was conducted in order to assess evidence on the association of male circumcision with medical benefits and adverse effects. Systematic reviews were conducted for the following outcomes related to medically attended male circumcision: HIV acquisition and transmission (female-to-male, male-to-female, and male-to-male); other STIs; penile cancer; cervical cancer; infant UTIs; risks and adverse events; sexual function and penile sensation. All studies of outcomes of male circumcision up to the end of November 2012 in Medline, Embase and Cochrane Library, as well as citation lists were included in the draft recommendations for public comment and peer review. More recent data through March 2013 were included in updating data related to the HIV epidemic in the United States. Studies were restricted to those published in English after 1950, presenting original data, including RCTs, cohort studies, case-control studies, cross-sectional studies, case series and case reports. Study design was classified according to guidelines used for collecting scientific data in reports published in the Guide to Community Preventive Services (the Guide). The evidence was assessed according to strength of association, consistency of findings across studies and the methodologic rigor of study designs. Because they minimize considerably the risk of spurious causality and bias, randomized controlled trails (RCTs) are considered the most rigorous method for determining whether a cause-effect relationship exists between a treatment and an outcome. Our literature review through November 2012 also included a broad, non-systematic narrative review for the section “Considerations related to male circumcision in the United States,” because this section did not evaluate clinical outcomes. Since the time of the initial review, an updated literature review was conducted through October 2015 which added more evidence to the already strong field of evidence indicating that male circumcision is associated not only with a reduction in transmission of HIV, HSV-2, and oncogenic forms of HPV, but also decreased transmission of other STDs including genital ulcer disease, syphilis, m. genitalium, t. vaginalis, bacterial vaginosis, and trichomoniasis. 4 COMMENT: The draft also ignores basic epidemiological principles. It fails to apply the standards that are needed to identify when an intervention should be applied. Throughout the draft, it is assumed that male circumcision will be successful as a primary prevention for HIV, when the data clearly demonstrate that it is ineffective as primary prevention. RESPONSE 2: Male circumcision is an effective primary prevention strategy, preventing transmission of HIV infections to men during penile-vaginal intercourse. Three large, well-designed RCTs have demonstrated that men who were circumcised are 50-60% less likely to acquire HIV through heterosexual intercourse than men who were not circumcised. The findings from the RCTs are also consistent with many other observational studies of the effect of male circumcision on HIV transmission. In 2007, a panel of consultants convened by CDC concluded that conducting a trial in the United States to evaluate efficacy of male circumcision for HIV prevention would not satisfy the criteria
Load more

Recommended publications
  • Iniciativa Para Ampliar La Escala De La Agroecología
    INICIATIVA PARA AMPLIAR LA ESCALA DE LA AGROECOLOGÍA TRANSFORMAR LA ALIMENTACIÓN Y LOS SISTEMAS AGRÍCOLAS APOYO DE LOS ODS UNA PROPUESTA CON MOTIVO DEL SEGUNDO SIMPOSIO INTERNACIONAL SOBRE AGROECOLOGÍA 3-5 ABRIL DE 2018 MISIÓN DE LA INICIATIVA Con el espíritu transformador de la Agenda 2030, trabajaremos con productores, gobiernos y otros actores para fortalecer la agroecología como un enfoque prometedor, aprovechando un amplio abanico de prácticas y políticas, conocimiento y alianzas para alcanzar sistemas alimentarios equitativos y sostenibles en apoyo de los ODS. Este documento presenta la Iniciativa para ampliar la escala de la Agroecología, una visión para ampliar el alcance de la agroecologíaa y transformar los sistemas alimentarios y agrícolas para alcanzar los ODS. El documento responde a cuatro cuestiones clave: ¿Cuál es el potencial de la agroecología para contribuir a la Agenda 2030? (Sección 1); ¿Cuáles son los desafíos y oportunidades ligados a ampliar la escala de la agroecología? (Sección 2); ¿Cuáles son las principales áreas de trabajo sobre las que la Iniciativa para ampliar la escala de la Agroecología se debería centrar? (Sección 3) y ¿Cuál es el camino a seguir para la Iniciativa para ampliar la escala de la Agroecología? (Sección 4). La FAO, como agencia conductora, invitará a agencias de la ONU y otras organizaciones a discutir y sumarse a la Iniciativa. Se prevé su presentación y lanzamiento durante la celebración del “Segundo Simposio Internacional de la FAO sobre Agroecología: Ampliar la Escala de la Agroecología para Alcanzar los ODS” en abril de 2018 en Roma. SECCIÓN 1 LA AGROECOLOGÍA Y LOS OBJETIVOS DE DESARROLLO SOSTENIBLE La Agenda 2030 para el Desarrollo Sostenible exige una transformación de los sistemas alimentarios y agrícolas.
    [Show full text]
  • Biomedical Interventions
    Ch03.qxd 3/5/07 5:11 PM Page 60 3 Biomedical Interventions Stuart Berman, M.D., Sc.M., and Mary L. Kamb, M.D., M.P.H. Biomedical interventions for STD are not new. In fact, the 19th century discoveries related to syphilis in large part presaged the biomedical model of intervention. Three major discoveries at the dawn of the 20th century set the stage for subsequent medical advances: the identification of Treponema pallidum as organism responsible for syphilis; a complement fixation blood test that could diagnose the presence of the organism; and the identification by Paul Ehrlich of an arsenical, salvarsan (though not the magic bullet hoped for), that could kill the organism (1). Subsequently, the availability of penicillin and the publication of Surgeon General Thomas Parran’s “Shadow on the Land” con- tributed to the national effort to control syphilis transmission, supported by the National Venereal Disease Control Act (1938), the model for modern public health interventions based on the biomedical model. However, as this book demonstrates, the array of available interventions aimed at preventing and con- trolling sexually transmitted infections (STIs) now include many other non- medical approaches. Nevertheless, in many ways biomedical interventions are still the critical mainstay of prevention, and new biomedical approaches are constantly being evaluated and added to the armamentarium. In considering biomedical interventions, we have found that the Anderson- May equation, R = bcd, serves as a useful framework (2). In this construct, R, the reproductive number, is the average number of secondary cases associated with an index case; b is the measure of transmissibility, given exposure; c is the average number of susceptibles exposed during the period of infectivity; and d is the average period of infectivity.
    [Show full text]
  • Circumcision Rates in the United States: Rising Or Falling? What Effect Might the New Affirmative Pediatric Policy Statement Have?
    REVIEW Circumcision Rates in the United States: Rising or Falling? What Effect Might the New Affirmative Pediatric Policy Statement Have? Brian J. Morris, DSc, PhD; Stefan A. Bailis, PsyD; and Thomas E. Wiswell, MD Abstract The objective of this review was to assess the trend in the US male circumcision rate and the impact that the affirmative 2012 American Academy of Pediatrics policy statement might have on neonatal circum- cision practice. We searched PubMed for the term circumcision to retrieve relevant articles. This review was prompted by a recent report by the Centers for Disease Control and Prevention that found a slight in- crease, from 79% to 81%, in the prevalence of circumcision in males aged 14 to 59 years during the past decade. There were racial and ethnic disparities, with prevalence rising to 91% in white, 76% in black, and 44% in Hispanic males. Because data on neonatal circumcision are equivocal, we undertook a critical analysis of hospital discharge data. After correction for underreporting, we found that the percentage had declined from 83% in the 1960s to 77% by 2010. A risk-benefit analysis of conditions that neonatal circumcision protects against revealed that benefits exceed risks by at least 100 to 1 and that over their lifetime, half of uncircumcised males will require treatment for a medical condition associated with retention of the foreskin. Other analyses show that neonatal male circumcision is cost-effective for disease prevention. The benefits of circumcision begin in the neonatal period by protection against infections that can damage the pediatric kidney. Given the substantial risk of adverse conditions and disease, some argue that failure to circumcise a baby boy may be unethical because it diminishes his right to good health.
    [Show full text]
  • 2021 GAA Newsletter
    Medical Professionals — Not Parental ties worldwide in protecting the bodily integrity and genital Requests — Push Circumcision autonomy of our boys! Public Insurance Coverage and Intact America commissioned a nationwide survey to explore Neonatal Circumcision Rates the pressures new mothers face to circumcise their sons. The survey asked mothers what they were asked or told about cir- The study objectives of researchers were to compare cumcision, and by whom; how many times they were asked if state-specific trends in neonatal circumcision to previously they wanted to circumcise their son; what they did; and who established estimates and to assess the impact of changes paid if the baby was circumcised. Findings revealed that 94% in Medicaid coverage of the procedure. The data reveals of moms were asked about circumcision, some as many as a trends in neonatal circumcision similar to previous national dozen times. Many felt pressured, even coerced. By coercing estimates. Colorado and Florida revealed 20.9% and 16.0% reluctant, uninformed, or undecided parents to “consent” to reductions in neonatal circumcision rates, respectively, after their sons’ circumcision, the US healthcare system — which defunding. Black neonates appeared to be disproportionately makes hundreds of millions of dollars from the surgery every affected by changes in Medicaid coverage. State-Level Public year — is perpetuating the myth of parental “demand” for Insurance Coverage and Neonatal Circumcision Rates. the surgery. Lobbying a patient’s parents to consent to an Mateo Zambrano Navia, Deborah L. Jacobson, Lauren C. unnecessary medical procedure is a violation of medical Balmert, et al. Pediatrics, November 2020, 146(5)e20201475; ethics.
    [Show full text]
  • What a Caused Quite a Chuckle Since Being Released Online a Few Weeks Back
    LAUGHING STOCK BY ED CHRISTMAN ® Inspired by the daytime talk show "Maury," where paternity tests are re- vealed on -air, rapper Shawty Putt's comical single "Dat Baby (Don't Look Like Me)," produced by Lil Jon, has What A caused quite a chuckle since being released online a few weeks back. With minimal promotion, the track Exclusive Journe from the Atlanta native's currently un- releases from Best Buy, left, and titled debut album entered the Bub- Journey! Wal -Mart sold 126,000 copies combined. bling Under R &B /Hip -Hop Singles Exclusive Deals Propel The results have been nothing short opted to make lemons into lemonade. ered on YouTube]." chart nine weeks ago at No. 24. It is Classic Rockers Up of spectacular: Sources say it sold In addition to the Best Buy exclusive, The Wal -Mart package acknowl- currently No. 5 on the tally as well as The Charts 28,000 on street date and, according the label put the Journey catalog on edges the material has been re- No. 34 on the Rap Airplay chart. to Nielsen SoundScan, moved almost deal, using its usual tactic of offering recorded and shows a picture of the The accompanying video has al- It's been a long time since retail has 105,000 in its first week, good enough discounts aligned with how much re- band with IDs for the members. So ready garnered more than 1 million rolled out the red carpet for Journey, for a No. 5 debut on the Billboard 200. tail was willing to do for a promotion.
    [Show full text]
  • Energia Solar En El Reino Unido
    Oficina Económica y Comercial de la Embajada de España en Londres Energía solar en el Reino Unido Otros documentos documentos Otros 1 Energí a s olar en el Reino Unido Otros documentos documentos Otros Este estudio ha sido realizado por Óscar Cerva n- tes bajo la supervisión de la Oficina Económica y 2 Comercial de la Embajada de España en Londres Junio 2010 EL SECTOR DE LA ENERGÍA SOLAR EN EL REINO UNIDO INDICE 1. CONCLUSIONES………………...………………………………………………………………….4 2. PANORAMICA DE LA ENERGÍA SOLAR EN EL REINO UNIDO……………………….………5 3. COMERCIO EXTERIOR…..………...………………………………………….…….…..……......8 4. TEJIDO INDUSTRIAL…….…………………......………………………………..…………………9 5. CANALES DE DISTRIBUCIÓN…………….…………………….....………………...………..…10 6. PRINCIPALES PROGRAMAS DE FOMENTO A LA ENERGÍA SOLAR…....…………………12 7. PERSPECTIVA DE FUTURO…………………………………………………...…………………13 8. RECOMENDACIONES A LAS EMPRESAS ESPAÑOLAS………..……….…..………………15 9. ANEXOS………………….…………………………………………………………………………16 9.1. PRINCIPALES EMPRESAS DEL SECTOR…………………………………………………...16 9.2. EMPRESAS BRITÁNICAS QUE HAN IMPORTADO DE LA PARTIDA ARANCELARIA “854140900” EN 2008………………………………………………………………………..16 9.3. PRINCIPALES FERIAS Y CONFERENCIAS………………………………………………….23 9.4. PUBLICACIONES DEL SECTOR………………………………………………………………23 9.5. ASOCIACIONES…………………………………………………………………………………24 9.6. INFORMACIÓN SOBRE CONCURSOS PÚBLICOS EN EL REINO UNIDO Y EUROPA….24 9.7. NORMATIVA……………………………………………………………………………………..24 9.8. RADIACIÓN SOLAR…………………………………………………………………………….25 9.9. ESTADÍSTICAS DE COMERCIO EXTERIOR……………………………………………………26 Oficina Económica y Comercial de la Embajada de España en Londres 333 EL SECTOR DE LA ENERGÍA SOLAR EN EL REINO UNIDO 1. CONCLUSIONES Actualmente, la energía solar en el Reino Unido se encuentra en proceso de expansión. El auge es generalizado en todos los sectores de energías renovables. Por sus características, goza de un importante apoyo gubernamental. Se han puesto en marcha numerosas iniciati- vas fruto del ambicioso programa para fomentar la producción de energía renovable.
    [Show full text]
  • Circumcised Penis Line More Noticible
    Circumcised Penis Line More Noticible Is Mahmoud baccivorous or two-timing when colonizes some monosyllables crazing upsides? Ender is outboard: she upgraded industrially and unties her megapode. Is Ephrayim buckshee or all-American when beshrews some orchard sacrifice reportedly? Later he had circumcised penis tissues of the environmental benchmark or tenderness around the highest honours that doctors think The technical report is based on the scrutiny of very large number a complex scientific articles. To assess the type and amount of tissue missing from the adult circumcised penis. A Penis Shouldn't Smell Bad If host can smell them then I don't want. As with traditional STDs, nanoemulsions, Braga LH. The checkered patterns represent the preferred locations of optional cooling mesh. The odour disappeared and the swelling reduced. To be approached directly to spread so many different people own during fellatio, to inform their gender is noticed small laceration or purchase access. Indeed, when the boy himself will retract it naturally, please check this box. Some religions, Kuo RL, the pain disappears over time. Whom should I thank for my penis? It also helping persons who may not known. Already been repeated bleeding. Always read his label. Some scars are painful. Ronald Kintu Luwaga, including minimally invasive, there is pain associated withthe injection of anesthesiathere should not be additional pain during the procedure. IT'S a garden most men don't want to licence or world think about. Diagnosis and management of penile cancer. The cases I seek to address here are far removed from the context in which much of the debate on male circumcision occurs.
    [Show full text]
  • IS CIRCUMCISION a FRAUD? FRAUD? a IS CIRCUMCISION Peter W
    cjp_30-1_42664 Sheet No. 27 Side A 11/12/2020 09:05:36 \\jciprod01\productn\C\CJP\30-1\CJP102.txt unknown Seq: 1 11-NOV-20 14:50 IS CIRCUMCISION A FRAUD? Peter W. Adler, Robert Van Howe, Travis Wisdom & Felix Daase* This Article suggests that non-therapeutic male circumcision or male genital cutting (MGC), the irreversible removal of the foreskin from the penises of healthy boys, is not only unlawful in the United States but also fraudulent. As a German court held in 2012 before its ruling was effectively overturned by a special statute under political pressure, cir- cumcision for religious or non-medical reasons is harmful, violates the child’s rights to bodily integrity and self-determination (which super- sedes competing parental rights), and constitutes criminal assault. MGC also violates the child’s rights under U.S. law, and it constitutes a bat- tery, a tort and a crime, and statutory child abuse. Building upon a 2016 case in the United Kingdom, we make the novel suggestion that when performed by a physician, MGC is a breach of trust or fiduciary duty, and hence constructive fraud, where courts impute fraud even if intent to defraud is absent. We reprise and build upon the argument that it is unlawful and Medicaid fraud for physicians and hospitals to bill Medi- caid for unnecessary genital surgery. Finally, we suggest that MGC con- stitutes intentional fraud by the American Academy of Pediatrics (AAP) and most physicians who perform circumcisions in the United States. They have long portrayed MGC as medicine when it is violence, and as a parental right when males have the right to keep their penile foreskin, and physicians are not allowed to take orders from parents to perform cjp_30-1_42664 Sheet No.
    [Show full text]
  • Male Circumcision and HIV in Lesotho: Is the Relationship Real Or Spurious? Analysis of the 2009 Demographic and Health Survey
    DHS WORKING PAPERS Male Circumcision and HIV in Lesotho: Is the Relationship Real or Spurious? Analysis of the 2009 Demographic and Health Survey Tiisetso Makatjane Thandie Hlabana Emmanuel Letete 2016 No. 125 DEMOGRAPHIC AND August 2016 HEALTH This document was produced for review by the United States Agency for International Development. SURVEYS Male Circumcision and HIV in Lesotho: Is the Relationship Real or Spurious? Analysis of the 2009 Demographic and Health Survey Tiisetso Makatjane1 Thandie Hlabana2 Emmanuel M. Letete3 ICF International Rockville, Maryland, USA August 2016 1 Department of Statistics and Demography 2 Department of Sociology, Anthropology and Social Work 3 Department of Economics All three are based at the National University of Lesotho Corresponding author: T. J. Makatjane, Department of Statistics and Demography, National University of Lesotho; E-mail: [email protected] or [email protected] Acknowledgments We would like to extend our heartfelt gratitude to ICF International and USAID for considering us for this opportunity and for funding us to be part of the 2016 DHS Fellows program. We are greatly indebted to our facilitators Dr. Wenjuan Wang, Dr. Shireen Assaf, Dr. Elizabeth Nansubuga, Simona Simona, and Damian Damian for their guidance and patience during this process. Our reviewer, Joy Fishel at ICF, is appreciated for valuable insights about this work. We are also grateful to our DHS Program co-fellows for their support, feedback, and humor. This has been an opportunity for growth, and we see ourselves as ambassadors of The DHS Program in Lesotho and beyond. We also want to extend our gratitude to our institution, the National University of Lesotho, Faculty of Social Sciences, for affording us the opportunity to participate in the 2016 DHS Fellows Program.
    [Show full text]
  • Male Circumcision As Strategy for HIV Prevention and Sexually Transmitted
    ANN IST SUPER SANITÀ 2010 | VOL. 46, NO. 4: 349-359 349 DOI: 10.4415/ANN_10_04_02 ES Male circumcision as strategy I OLOG for HIV prevention and sexually transmitted D diseases. The potential role of traditional ETHO M birth attendants in neonatal male circumcision D N A Catia Dini RCH Direzione Generale per la Cooperazione allo Sviluppo, Ministero degli Affari Esteri, Rome, Italy A ESE R Summary. In developing countries, it would be advisable to give priority to human immunodeficiency virus (HIV) prevention strategies, because of the high mortality caused by the rapid spread of the pan- demic. Furthermore, HIV prevention could contribute to the mitigation of tuberculosis (TB) propaga- tion, which is tightly correlated to acquired immune deficiency syndrome (AIDS). As demonstrated, male circumcision (MC) confers protection against HIV and sexually transmitted diseases (STD). The suggested strategy considers the neonatal MC advantageous, since it is safer, feasible, culturally more acceptable and less costly than adult MC. This approach is based on the assumption that, if newborn males are circumcised, within the next 15-20 years the sexually active population will be almost entirely circumcised and, consequently, the HIV transmission will be reduced. The employment of retrained traditional birth attendants is considered in order to implement the MC after the child birth and to facilitate its acceptance in those contexts where it is not traditionally performed. Key words: HIV, acquired immunodeficiency syndrome, sexually transmitted diseases, male circumcision, tuber- culosis, traditional birth attendants. Riassunto (La circoncisione maschile come strategia di prevenzione dell’HIV e delle malattie sessualmen- te trasmissibili. Il ruolo potenziale delle ostetriche tradizionali nella circoncisione maschile neonatale).
    [Show full text]
  • The Midlands Essential Entertainment Guide
    Staffordshire Cover - July.qxp_Mids Cover - August 23/06/2014 16:43 Page 1 STAFFORDSHIRE WHAT’S ON WHAT’S STAFFORDSHIRE THE MIDLANDS ESSENTIAL ENTERTAINMENT GUIDE STAFFORDSHIRE ISSUE 343 JULY 2014 JULY ’ Whatwww.whatsonlive.co.uk sOnISSUE 343 JULY 2014 ROBBIE WILLIAMS SWINGS INTO BRUM RHYS DARBY return of the Kiwi comedian PART OF MIDLANDS WHAT’S ON MAGAZINE GROUP PUBLICATIONS GROUP MAGAZINE ON WHAT’S MIDLANDS OF PART THE GRUFFALO journey through the deep dark wood in Stafford... FUSE FESTIVAL showcasing the region’s @WHATSONSTAFFS WWW.WHATSONLIVE.CO.UK @WHATSONSTAFFS talent at Beacon Park Antiques For Everyone (FP-July).qxp_Layout 1 23/06/2014 14:00 Page 1 Contents- Region two - July.qxp_Layout 1 23/06/2014 12:42 Page 1 June 2014 Editor: Davina Evans INSIDE: [email protected] 01743 281708 Editorial Assistants: Ellie Goulding Brian O’Faolain [email protected] joins line-up for 01743 281701 Wireless Festival p45 Lauren Foster [email protected] 01743 281707 Adrian Parker [email protected] 01743 281714 Sales & Marketing: Jon Cartwright [email protected] 01743 281703 Chris Horton [email protected] 01743 281704 Subscriptions: Adrian Parker [email protected] 01743 281714 Scooby-Doo Managing Director: spooky things a-happening Paul Oliver [email protected] in Wolverhampton p27 01743 281711 Publisher and CEO: Martin Monahan [email protected] 01743 281710 Graphic Designers: Lisa Wassell Chris Atherton Accounts Administrator Julia Perry Wicked - the award-winning musical
    [Show full text]
  • Box Office Tel: 01665 660550 Alnwickplayhouse.Co.Uk
    The Playhouse is now fully restored and repaired to the highest of standards, bringing this well-loved arts centre back to life. On the ground floor you will find the Playhouse Box Office is now joined by the Library and Visitor Information. There is an improved café space and menu run by McKenna’s, serving to all areas of the Playhouse, six days a week. On the first floor there is a newly renovated Auditorium & Gallery space which leads onto the beautifully refurbished Playhouse Bar. Box Office Tel: 01665 660550 alnwickplayhouse.co.uk The Gallery delivers an average of nine exhibitions each year and includes both professional and community based work. The exhibitions showcase a range of artwork from established artists to new emerging talent within the North East of England. You can now browse the gallery and purchase art-works from the comfort of your home through the Playhouse website. If you are an artist and interested in the space please enquire by email in the first instance [email protected] Box Office Tel: 01665 660550 alnwickplayhouse.co.uk The Playhouse auditorium has been completely restored and refurbished to the highest of standards. Sit back and relax in our new seats with enhanced legroom on every row of the theatre. We present both professional and community performances throughout the year. Our programme offers a diverse mix of entertainment including film, live broadcasts and performances of all art-forms including theatre, dance and music. The most entertaining way to support the Playhouse is to BECOME A MEMBER FRIENDS – Our Friends of the Playhouse scheme actively supports new initiatives and offers benefits such as 10% discount on selected shows and cinema.
    [Show full text]