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Master Regulators of Inflammation and Cancer
NOD-like Receptors: master regulators of inflammation and cancer Mansi Saxena1 & Garabet Yeretssian1,2¶ 1Department of Medicine, Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA 2Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA ¶ Correspondence to: Garabet Yeretssian, PhD Department of Medicine, Clinical Immunology, Immunology Institute, Tisch Cancer Institute Icahn School of Medicine at Mount Sinai 1425 Madison Avenue, 12-20E New York, NY 10029, USA Tel: (212) 659-9391; (212) 659-9269 Fax: (212) 849-2525 E-mail: [email protected] 1 ABSTRACT Cytosolic NOD-like receptors (NLRs) have been associated with human diseases including infections, cancer, and autoimmune and inflammatory disorders. These innate immune pattern recognition molecules are essential for controlling inflammatory mechanisms through induction of cytokines, chemokines and antimicrobial genes. Upon activation, some NLRs form multi- protein complexes called inflammasomes, while others orchestrate caspase-independent Nuclear factor kappa B (NF-κB) and Mitogen activated protein kinase (MAPK) signaling. Moreover, NLRs and their downstream signaling components engage in an intricate crosstalk with cell death and autophagy pathways, both critical processes for cancer development. Recently, increasing evidence has extended the concept that chronic inflammation caused by abberant NLR signaling is a powerful driver of carcinogenesis, where it abets genetic mutations, tumor growth and progression. In this review, we explore the rapidly expanding area of research regarding the expression and functions of NLRs in different types of cancers. Furthermore, we particularly focus on how maintaining tissue homeostasis and regulating tissue repair may provide a logical platform for understanding the liaisons between the NLR-driven inflammatory responses and cancer. -
The South Africa of Tomorrow Needs Answers That Last. That’S Why We’Re Building Them Today, with Customers All Over the Country
Macan S Diesel_210 x 210_Porsche 210x275 2014/10/22 3:01 PM Page 1 The South Africa of tomorrow needs answers that last. www.porschesouthafrica.com That’s why we’re building them today, with customers all over the country. Lasting memories. Per litre. The new Porsche Macan S Diesel. Life, intensified. It’s why we’re designing our technology to last We’re helping develop South Africa’s longer and use fewer resources. It’s why we’re infrastructure, promoting skills development and Do intense moments have to be fleeting? With high performance helping our customers to improve their energy ensuring sustainable economic growth through engines and technologies tested on the race track, the new efficiency and increase their productivity. And it’s projects across the country. In energy, industry, Porsche Macan S Diesel provides a lasting endorphin rush, why we’re pioneering new answers with one of infrastructure and healthcare. with minimal fuel consumption. Performance and efficiency, Porsche Centre Johannesburg the world’s largest environmental portfolios. highly intensified. Tel: 011 540 5000 We’re working with South Africa today to create Porsche Centre Cape Town Yet, we’d never claim to have all the answers. answers that last for the South Africa of Tel: 021 555 6800 That’s why we’ve been working with customers in tomorrow. Porsche Centre Umhlanga South Africa for more than 150 years. Tel: 031 514 3000 siemens.com • • • • Fuel consumption in l/100 km: city 6.7; highway 5.7; combined 6.1 CO2 emissions: 159 g/km Power: 180 kW (245 hp) Torque: 580 Nm 0 - 100 km/h in 6.3 seconds HERAUSGEBER Deutsche Internationale Schule Johannesburg P. -
134. Jahrgang Sonderheft 1A 2017 Seite 1–283
Geleitet von P. Mayer und H. Hasenauer Gegründet 1875 134. Jahrgang Sonderheft 1a 2017 Seite 1–283 Gegründet im Jahre 1875 von den Forstinstituten der Universität Seite B für Bodenkultur (BOKU) und des Bundesforschungs- und Ausbildungszentrum für Wald, Naturgefahren und Landschaft (BFW) Ziel: Das Centralblatt für das gesamte Forstwesen veröffentlicht wissenschaftliche Arbeiten aus den Bereichen Wald- und Holzwissen-schaften, Umwelt und Natur- schutz, sowie der Waldökosystemforschung. Die Zeitschrift versteht sich als Binde- glied von Wissenschaftlern, Forstleuten und politischen Entscheidungsträgern. Da- her sind wir auch gerne bereit, Überblicksbeiträge sowie Ergebnisse von Fallbeispielen sowie Sonderausgaben zu bestimmten aktuellen Themen zu veröffent-lichen. Englische Beiträge sind grundsätzlich erwünscht. Jeder Beitrag geht durch ein international übliches Begutachtungsverfahren. Aims and scope: The Austrian Journal of Forest Science publishes scientific papers related to forest- and wood science, environmental science, na- tural protections as well as forest ecosystem research. An important scope of the journal is to bridge the gap between scientists, forest managers and policy deci- sion makers. We are also interested in discussion papers, results of specific field studies and the publishing of special issues dealing with specific subjects. We are pleased to accept papers in both German and English. Every published article is peer-reviewed. Gründungsherausgeber: Rudolf Micklitz, 1875 Herausgeber: Dipl.-Ing. Dr. Peter Mayer Univ.-Prof. -
June 2021 Spring Convocation Program
Convocation 2021 Welcome to Convocation Thank you for joining us for today’s ceremony. We’re so glad to have you with us to cerebrate and honour the class of 2021. If you want to share your support of a special graduate, post a message or photo to #ucalgarygrad, and it will be displayed on the convocation web page during the event. Please enjoy the celebration! We acknowledge the traditional territories of the people of the Treaty 7 region in Southern Alberta, which includes the Blackfoot Confederacy (comprising the Siksika, Piikani, and Kainai First Nations), as well as the Tsuut’ina First Nation, and the Stoney Nakoda (including the Chiniki, Bearspaw, and Wesley First Nations). The City of Calgary is also home to Métis Nation of Alberta, Region III. The University of Calgary is situated on land adjacent to where the Bow River meets the Elbow River, and the traditional Blackfoot name of this place is “Moh’kins’tsis,” which we now call the City of Calgary. Congratulations Class of 2021 Greetings from the Chancellor 2 Greetings from the President 3 Ceremonial Traditions 4 Honouring Exceptional Individuals 5 Degrees Granted 5 Academic Regalia 5 Honorary Degree Recipients 6 Order of the University of Calgary Recipients 7 Ceremony Program 8 Faculties and Graduates Cumming School of Medicine 9 Faculty of Arts 12 Faculty of Kinesiology 20 Faculty of Law 23 Faculty of Nursing 25 Faculty of Science 27 Faculty of Social Work 33 Faculty of Veterinary Medicine 36 Haskayne School of Business 38 School of Architecture, Planning and Landscape 43 Schulich School of Engineering 45 Werklund School of Education 54 UCalgary Alumni 58 Thank You 59 Graduates’ Pledge 60 Spring 2021 Convocation 1 Greetings from the Chancellor Dear Graduates, Welcome to your virtual convocation ceremony! This milestone marks a significant step on an educational journey that doesn’t end here. -
Bib First Name Last Name Gen. Division Net Time Place Gen/Pl. Div/Pl
Bib First Name Last Name Gen. Division Net Time Place Gen/Pl. Div/Pl. 80902 Abagail S F F40-49 3:27:06 66360 32711 6211 80897 Bob S M M60-69 3:13:45 65044 33053 1355 80893 Jacob S M M30-39 3:06:48 64052 32712 9313 55637 Stan S M M30-39 1:18:51 15568 11917 4053 81090 Jose Manuel Saa Gonzalez M M30-39 2:15:01 48522 27438 8160 61328 James Saab M M16-19 2:30:00 53440 29211 1081 43483 Layal Saab F F16-19 1:53:40 41275 16685 530 82049 Ahsan Abdullah Saad M M20-29 1:19:30 16219 12310 3438 15556 Daniel Saad M M30-39 1:05:31 4286 3838 1425 61861 Elizabeth Saad F F50-59 2:28:46 53014 23877 2291 22269 Gabrielle Saad F F20-29 1:49:03 39234 15515 5462 42491 Michael Saad M M30-39 1:34:13 29926 19566 6223 78416 Michael Saad M M20-29 2:10:44 47201 26905 7202 56310 Melissa Saadat F F30-39 1:28:47 25331 7899 2542 30031 Usman Saadat M M40-49 1:29:23 25870 17663 3510 30533 Yoav Saar M M40-49 1:35:15 30720 19939 3907 67246 Alexander Saba M M20-29 2:43:00 57977 30760 7963 47682 Anthony Saba M M20-29 2:43:01 57984 30762 7964 59620 Delight Saballa F F20-29 2:45:47 58907 27738 8720 14086 Martin Sabanos M M30-39 1:22:52 19571 14270 4718 83238 Charm Sabater F F20-29 3:24:22 66148 32574 9588 54336 Paola Sabatini F F30-39 1:30:22 26724 8605 2740 88907 Georges Sabbagh M M30-39 2:51:16 60479 31544 9046 38510 Joanna Sabbouh F F30-39 1:39:38 33711 12409 3833 39425 Nick Sabel M M50-59 1:33:22 29196 19227 1889 27934 Midhat Saber M M40-49 1:33:55 29674 19447 3805 60843 Beheshteh Sabeti F F50-59 1:58:55 43425 17977 1484 32433 Neda Sabeti F F20-29 1:32:36 28619 9631 3430 58534 -
Proceedings.Pdf
PEDIATRIC PULMONOLOGY PEDIATRIC ISSN 8755-6863 VOLUME 52 SUPPLEMENT 46 JUNE 2017 PEDIATRIC PULMONOLOGY Volume 52 • Supplement 46 • June 2017 Proceedings S1 Foreword PEDIATRIC PULMONOLOGY S2 Keynote Speaker S4 Post Graduate Course S17 I. Plenary Sessions S32 II. Topic Sessions S94 III. Young Investigator Oral Communications S100 IV. Posters S177 Index Volume 52 Supplement 46 June 2017 52 Supplement 46 June Volume 16th International Congress of Pediatric Pulmonology Lisbon Portugal, June 22–25, 2017 Pages S1 –S182 Pages ONLINE SUBMISSION AND PEER REVIEW http://mc.manuscriptcentral.com/ppul PEDIATRIC PULMONOLOGY Editor-in-Chief: THOMAS MURPHY, Watertown, MA USA Deputy Editor: TERRY NOAH, Chapel Hill, NC USA Associate Editors: ANNE CHANG, Brisbane, Queensland, Australia STEPHANIE DAVIS, Indianapolis, IN USA ALEXANDER MOELLER, Zurich, Switzerland KUNLING SHEN, Beijing, China PAUL STEWART, Chapel Hill, NC USA STEVEN TURNER, Aberdeen, Scotland, United Kingdom Topic Editors: JUDITH VOYNOW, Richmond, VA USA HEATHER ZAR, Cape Town, South Africa Managing Editor: ELIZABETH BRENNER, Malden, MA USA Editorial Board Richard Auten Brigitte Fauroux Min Lu Jürgen Schwarze Durham, NC USA Paris, France Shanghai, China Edinburgh, Scotland Avi Avital Michael Fayon George B. Mallory, Jr. Hiran Selvadurai Bordeaux, France Houston, TX USA Jerusalem, Israel Sydney, Australia Ian Balfour-Lynn Shona Fielding Franc¸ois Marchal Aberdeen, Scotland Nancy, France Renato Stein London, UK Porto Alegre, Brazil Monika Gappa Susanna McColley Eugenio Baraldi Wesel, Germany Chicago, IL USA Mary Sunday Padova, Italy Ben Gaston Mark Montgomery Durham, NC USA Lea Bentur Cleveland, OH USA Calgary, AB Canada Haifa, Israel Masato Takase Robert P. Gie Thomas Nicolai Tokyo, Japan David Birnkrant Tygerberg, South Africa Munich, Germany Cleveland, OH USA Asher Tal David Gozal Cathy Owens Beer-Sheva, Israel Hans Bisgaard Chicago, IL, USA London, UK Copenhagen, Denmark Anne Greenough Stacey Peterson-Carmichael Alejandro Teper Frank J. -
Nation Esa 2015
DIFFE/ RENCES INEQUA/ LITIES AND SOCIO/ LOGICAL IMAGI/ NATION ESA 2015 12TH CONFERENCE OF THE EUROPEAN SOCIOLOGICAL ASSOCIATION 2015 PROGRAMME BOOK DIFFE/ RENCES INEQUA/ LITIES AND SOCIO/ LOGICAL IMAGI/ NATION ESA 2015 12TH CONFERENCE OF THE EUROPEAN SOCIOLOGICAL ASSOCIATION 2015 PROGRAMME BOOK Prague, 25–28 August 2015 ESA 12th Conference Differences, Inequalities and Sociological Imagination www.esa12thconference.eu Organizers IS CAS – Institute of Sociology of the Czech Academy of Sciences – www.soc.cas.cz ESA – European Sociological Association – www.europeansociology.org/ Programme book ISBN 978-80-7330-271-9 PRAGUE, 25–28 AUGUST 2015 ESA 12TH CONFERENCE DIFFERENCES, INEQUALITIES AND SOCIOLOGICAL IMAGINATION PROGRAMME BOOK EUROPEAN SOCIOLOGICAL ASSOCIATION (ESA) INSTITUTE OF SOCIOLOGY OF THE CZECH ACADEMY OF SCIENCES (IS CAS) DIFFERENCES, INEQUALITIES AND SOCIOLOGICAL IMAGINATION DIFFE/ RENCES INEQUA/ LITIES AND SOCIO/ LOGICAL IMAGI/ NATION 6 6 The Theme A profound challenge that the social sciences, and sociology in particular, are now called upon to confront has to do with the depth and extraordinary acceleration of global processes of social and cultural change … … Today's byword 'globalisation' only partially that the international economic crisis has exacerbated captures the full significance of these processes. beyond measure. This situation threatens the very Sociological knowledge therefore encounters existence of democracy and calls for the construction a limitation: it is easier to see what is disappearing of forms of social analysis which are strongly than what is coming into being. Yet this limitation connected to the arena of public policy. Concurrently, can be overturned and become a resource: a stimulus these forms of analysis must also be capable of to intensify our theoretical and empirical exploration offering communities and individuals knowledge and of the world around us by relating everyday life insight that can help to stem the tide of fatalism and to history, connecting individual experiences to apathy. -
Noms De Famille Issus De L'artisanat En France Et En Pologne
ROCZNIKI HUMANISTYCZNE Tom LXVI, zeszyt 8 – 2019 DOI: http://dx.doi.org/10.18290/rh.2019.67.8-5 IWONA PIECHNIK1 NOMS DE FAMILLE ISSUS DE L’ARTISANAT EN FRANCE ET EN POLOGNE SURNAMES FROM ARTISAN NAMES IN FRANCE AND IN POLAND Abstract The article analyses surnames originating from artisan names in France and in Poland. It presents their origins (including foreign influences), types and word formation. We can see, among other things, that the French surnames are shorter, but have many dialectal variants, while the Polish surnames are longer and have a richer derivation. The article also focuses on demographic statis- tics of such surnames in both countries: the blacksmith as an etymon is the most popular. In the top 50, there are also in France: baker, miller and mason; while in Poland: tailor and shoemaker. Key words: family names; surnames; patronyms; handicraft; artisan. Les plus anciens noms de famille issus des domaines de l’artisanat en France et en Pologne remontent au Moyen Âge, donc à l’époque où le sys- tème féodal se renforçait et les villes commençaient à se développer, en nourrissant surtout les ambitions des nobles de construire leurs demeures seigneuriales, et des gens de petits métiers venaient s’installer tout autour naturellement. Dans des bourgs, c’est-à-dire dans de gros villages où se te- naient ordinairement des marchés, les bourgeois bénéficiaient d’un statut privilégié et développaient le commerce et la conjoncture de la manufacture, donc il y avait aussi beaucoup de travail pour différents métiers. C’est juste- ment dans les bourgs et les villes que l’artisanat se développait le mieux, en 1 Dr hab. -
2008-2009 Annual Report | 1 Table of Contents
Department of Surgery Annual Report July 1, 2008 – June 30, 2009 R.S. McLaughLin PRofessoR and chair Dr. R.K. Reznick Associate chaiR and Vice-chairs Dr. B.R. Taylor Associate Chair / James Wallace McCutcheon Chair in Surgery Dr. D.A. Latter Vice-Chair, Education Dr. R.R. Richards Vice-Chair, Clinical Dr. B. Alman Vice-Chair, Research / A.J. Latner Professor and Chair of Orthopaedic Surgery SuRgeonS-in-chief Dr. J.G. Wright The Hospital for Sick Children / Robert B. Salter Chair in Surgical Research Dr. J.S. Wunder Surgeon-in-Chief / Rubinoff-Gross Chair in Orthopaedic Oncology Dr. L.C. Smith St. Joseph’s Health Centre Dr. O.D. Rostein St. Michael’s Hospital Dr. R.R. Richards Sunnybrook Health Sciences Centre Dr. L. Tate Toronto East General Hospital Dr. B.R. Taylor University Health Network / James Wallace McCutcheon Chair in Surgery Dr. J.L. Semple Women’s College Hospital uniVersity diViSion chairs Dr. M.J. Wiley Anatomy Dr. R.D. Weisel Cardiac Surgery (until June 30, 2009) Dr. C. Caldarone Cardiac Surgery (effective July 1, 2009) Dr. Z. Cohen General Surgery | Bernard and Ryna Langer Chair (until June 30, 2009) Dr. A. Smith General Surgery | Bernard and Ryna Langer Chair (effective July 1, 2009) Dr. J.T. Rutka Leslie Dan Professor and Chair of Neurosurgery Dr. B. Alman A.J. Latner Professor and Chair of Orthopaedic Surgery Dr. D.J. Anastakis Plastic Surgery Dr. S. Keshavjee F.G. Pearson | R.J. Ginsberg Chair in Thoracic Surgery Dr. S. Herschorn Martin Barkin Chair in Urological Research Dr. T. -
2021 Program.Pdf
The 146th Annual Ceremony Saturday, June 12, 2021 UNIVERSITY OF WASHINGTON 146th Annual Commencement Saturday, June 12, 2021 Program of Exercises table of contents Order of Events .............................................................................................................................2 A World of Good ...........................................................................................................................4 University Awards and Medalists .................................................................................................6 Commencement Speaker ............................................................................................................8 UW Administration .......................................................................................................................9 Baccalaureate Honors ................................................................................................................10 Professional Degrees .................................................................................................................14 Doctoral Degrees ........................................................................................................................18 Master’s Degrees ........................................................................................................................22 Baccalaureate Degrees ..............................................................................................................36 Commissions ..............................................................................................................................68 -
Dean's List Fall 2016
Dean's List Fall 2016 Page Monte Ahuja College of Business 2 College of Education and Human Services 7 Washkewicz College of Engineering 9 College of Liberal Arts and Social Sciences 13 School of Nursing 20 College of Sciences and Health Professions 23 University Studies 31 Maxine Goodman Levin College of Urban Affairs 32 Dean's List FALL 2016 Monte Ahuja College of Business Abdelrahman Abed Jacquelyn Banas Samuel Caspio Bilal Abed Olimpia Barnes Joanne Celestina Lorraine Abeysinghe Steven Barnes Jake Cermak Kevin Adams Megan Barrick Jason Chadwell Andres Aguirre Waleed Abdullah Basalasil Mathew Chahda Andrijana Akovic Alexander Baszuk Ian Chandler Dana Salim Gharib Al Ajmi Ethan Beastrom Taylor Charnock Mohammed Abdullah Al Hanfoosh Brice Bechtel Amer Chebat Budoor Saleh Mohamed Al Harooni Brandon Beck Ali Chehade Ahmed A Al Kindi Kwasi Bediako Elizabeth Cherep Al warith Said Hamed Al Mahrouqi Brandon Beets Amanie Cherry Nesreen Nasser Al Yahyai Jonathan Belliveau Arielle Chopka Mohammad Alanazi Cecilia Bennett Rachael Chrzanowski Zayd Albakri Taylor Berila Alyssa Church Alexis Albro Vincent Bertrand Khrystyna Chyzhevska Kevin Albro Tiffany Bianco Conor Cicon Mohammed Abdullah Albseeri Vincent Bielek Morgan Clark Abdullah Dawood Aldawood Erin Black Owen Clawges Dmitrii Alexeenco Leah Blackley Sara Clawson Mohammed Abdulrahman Alghunaim Kali Blankenship Ronald Clay Majed Abdullah Alhanfoosh David Blate Ashley Clelland Khaled Aljammal Troy Bloom Bradley Clemens Abdullah Hamed Aljohani Frank Boccabella Charles Cole Fahad Abdulmohsen Alkhurayyif -
Government Gazette Republic of Namibia
GOVERNMENT GAZETTE OF THE REPUBLIC OF NAMIBIA N$109.80 WINDHOEK - 17 February 2020 No. 7121 CONTENTS Page GENERAL NOTICES No. 67 The Metal Box Pension Fund: Statement of unclaimed moneys ........................................................... 1 No. 68 The Namib Fisheries Provident Fund: Statement of unclaimed moneys ............................................... 2 No. 69 The Novanam Group Retirement: Statement of unclaimed moneys ..................................................... 3 No. 70 Orion Pension and Provident Funds: Statement of unclaimed moneys ................................................. 8 ________________ General Notices THE METAL BOX PENSION FUND No. 67 2020 STATEMENT OF UNCLAIMED MONEYS MEMBER DATE OF SURNAME INITIALS EMPLOYER BENEFIT NUMBER BIRTH 1 LUKAS O 19650412 METAL BOX NAMIBIA 54,594.01 2 CLAASEN WR 19721016 METAL BOX NAMIBIA 46,057.13 3 FINNIES HG 19720115 METAL BOX NAMIBIA 72,313.03 4 DAUSAB SM 19640330 METAL BOX NAMIBIA 36,638.57 5 GOLIATH PJ 19541105 METAL BOX NAMIBIA 63,620.37 6 SHIGWEDHA AN 19780308 METAL BOX NAMIBIA 23,266.58 7 SHIKONGO BB 19760206 METAL BOX NAMIBIA 29,567.11 8 HAMBIRA C 19671115 METAL BOX NAMIBIA 23,908.41 9 MUPIKA AM 19610505 METAL BOX NAMIBIA 19,198.07 10 PAMPLIN ACV 19721021 METAL BOX NAMIBIA 21,417.04 2 Government Gazette 17 February 2020 7121 11 LINDSAY-PAYNE WC 19751110 METAL BOX NAMIBIA 2,345.79 12 VAN EEDEN JA 19450107 METAL BOX NAMIBIA 422,909.42 13 NASIMA G 19630829 METAL BOX NAMIBIA 201,563.56 14 MOUTON HM 19551101 METAL BOX NAMIBIA 98,574.74 ________________ THE NAMIB