FALL 2008

VOLUME 1 • NUMBER 5 Public Health Foundation, Incorporated BOARD OF DIRECTORS

Susanne Glen Moulton, JD, MPH, President Leah Devlin, DDS, MPH Jacky Ann Rosati, PhD Director State Health Director and Environmental Scientist and Containment Patient Assistance and Reimbursement Programs Director, Division of Public Health Area Lead GlaxoSmithKline N.C. Department of Health and Human Services U.S. Environmental Protection Agency National Homeland Security Research Center Jack E. Wilson, MSENV, Vice President Cynthia J. Girman, DrPH Retired Senior Director, Department of Epidemiology Ilene C. Siegler, PhD, MPH Board of Directors Merck Research Laboratories Professor of Medical Psychology TEC, Incorporated Duke University Shelley D. Golden, MPH Delton Atkinson, MPH, MPH, PMP Lecturer Paula Brown Stafford, MPH Deputy Director Department of Health Behavior and Executive Vice President Division of Vital Statistics Health Education Global Data Management and Biostatistics National Center for Health Statistics UNC School of Public Health Quintiles Transnational Corporation Centers for Disease Control and Prevention Sandra W. Green, MBA, MHA, BSPH Russell B. Toal, MPH Ronald E. Aubert, PhD, MSPH President Visiting Associate Professor of Public Health Vice President, Clinical Analytics, East Coast Customer Management Group Institute of Public Health Outcomes and Reporting MedAssets, Incorporated Georgia State University Medco Health Solutions, Incorporated C. David Hardison, PhD John C. Triplett, MD, MPH David J. Ballard, MD, MSPH, PhD, FACP Corporate Vice President, Life Sciences Regional Medical Officer Senior Vice President and Chief Quality Officer Science Applications International Corporation Bethesda, MD Baylor Health Care System Deborah Parham Hopson, PhD, RN Robert D. Verhalen, DrPH Executive Director and BHCS Endowed Chair Assistant Surgeon General Chief Executive Officer Institute for Health Care Research and Improvement Associate Administrator, HIV/AIDS Bureau Verhalen and Associates, LLC Health Resources and Services Administration Fred T. Brown, Jr., MPH, FACHE G. Robert Weedon, DVM, MPH Managing Director, Business Development Joan C. Huntley, PhD, MPH Adjunct Faculty in Honors and Biology Carolinas HealthCare System Adjunct Professor of Epidemiology University of North Carolina Wilmington Kelly B. Browning, MA UNC Gillings School of Global Public Health Vice-Chairman Executive Vice President Mark H. Merrill, MSPH New Hanover County Board of Health American Institute for Cancer Research President Senior Partner Deniese M. Chaney, MPH Presbyterian Hospital of Dallas College Road Animal Hospital, PLLC Senior Manager, Healthcare Practice Douglas M. Owen, PE, BCEE Alice D. White, PhD Accenture Health and Life Sciences Vice President Vice President Stacy-Ann Christian, JD, MPH Malcolm Pirnie, Incorporated Worldwide Epidemiology Department GlaxoSmithKline Assistant Director Jonathan J. Pullin, MS Clinical and Health Services Research President and Chief Executive Officer Thomas K. Wong, PhD Michael (Trey) A. Crabb, III, MHA, MBA The Environmental Group of the Carolinas, Vice Presiden Managing Director, Investment Banking Incorporated Meganium Corporation Avondale Partners, LLC Roy J. Ramthun, MSPH President HSA Consulting Services, LLC

2008 School of Public Health ADVISORY COUNCIL Dennis Gillings, CBE, Chair Ken Eudy Guy Miller, MD, PhD Chairman and Chief Executive Officer Chief Executive Officer Chairman and Chief Executive Officer Quintiles Transnational Corporation Capstrat Edison Pharmaceuticals, Incorporated William K. Atkinson, PhD, MPH Robert J. Greczyn, Jr., MPH Carmen Hooker Odom, MS President and Chief Executive Officer President and Chief Executive Officer President WakeMed BlueCross and BlueShield of North Carolina Milbank Memorial Fund Joseph Carsanaro, MBA, MSEE James R. Hendricks, Jr., MS Jane Smith Patterson General Manager Vice President of Environment, Executive Director Personal Communications Sector Health and Safety (Retired) The e-NC Authority Motorola, Incorporated Duke Energy Joan Siefert Rose, MPH Willard Cates, Jr., MD, MPH J. Douglas Holladay, MDiv President President, Research General Partner Council for Entrepreneurial Development Family Health International Park Avenue Equity Partners, LP Alexandria Technology Center Andrew Conrad, PhD Donald A. Holzworth, MS Charles A. Sanders, MD Chief Scientific Officer Chairman Chapel Hill, NC National Genetics Institute Expression Analysis, Inc. Michael C. Tarwater, MHA, FACHE Keith Crisco, MBA David P. King President and Chief Executive Officer President President and Chief Executive Officer Carolinas HealthCare System Asheboro Elastics Corporation Laboratory Corporation of America Paul M. Wiles, MHA Nancy A. Dreyer, PhD, MPH John McConnell President and Chief Executive Officer Chief of Scientific Affairs Raleigh, NC Novant Health, Incorporated OUTCOME contentsfall 2008 4 O n Sept. 26, 2008, Chancellor Holden Thorp officially recognizes our School as the UNC Gillings School of Global Public Health. 10 Holden Thorp features & news

4 THE PUBLIC HEALTH LANDSCAPE: CHALLENGES AND OPPORTUNITIES 16 9 GILLINGS GIFT POSITIONS UNC TO BETTER MEET 21ST CENTURY PUBLIC HEALTH CHALLENGES

10 DENNIS GILLINGS: DRAWING STRENGTH, EXPERIENCING SUCCESS, NOW RETURNING TO HIS ROOTS

14 JOAN GILLINGS: INSPIRING OTHERS WITH A CAN-DO ATTITUDE

16 A PLACE FOR RIGOR: SINCE 1949, UNC’S RESEARCHERS SET THE PACE 22 FOR BIOSTATISTICS 21 UNDERSTANDING THE PUBLIC: UNC’S SURVEY RESEARCH UNIT HELPS RESEARCHERS COLLECT HIGH-QUALITY DATA

22 UNC’S COLLABORATIVE STUDIES COORDINATING CENTER: CONTROLLING QUALITY, MANAGING DATA, CHANGING THE PRACTICE OF MEDICINE 26 24 GARY KOCH: A MENTOR FOR LIFE 26 ANTICIPATING PUBLIC HEALTH NEEDS; ACCELERATING PUBLIC HEALTH SOLUTIONS

29 GILLINGS INNOVATION LABS FOCUS INTERDISCIPLINARY EFFORTS ON TOUGH PUBLIC HEALTH PROBLEMS

31 NORTH CAROLINA MENTAL HEALTH SYSTEM IMPROVEMENT

32 VACCINES FOR GLOBAL HEALTH

continued

CAROLINA PUBLIC HEALTH | 1 DEAN Barbara K. Rimer, DrPH fall 2008 DIRECTOR OF COMMUNICATIONS Ramona DuBose

EDITOR Emily J. Smith

ASSOCIATE DEAN contents continued 33 45 48 FOR EXTERNAL AFFAIRS Peggy Dean Glenn

DESIGN AND PRODUCTION Sheila Johnston Sherer 33 UNC BIOSTATISTICIANS MAKE THE NUMBERS ADD UP IN BIOMEDICAL RESEARCH Sherer Graphic Design 40 SIX DEGREES OF BIOSTATISTICS CONTRIBUTING WRITERS 42 SCHOOL NEWS Margarita De Pano, Kim Gazella, Linda Kastleman, Kathleen Kearns, 48 AWARDS AND RECOGNITIONS Angela Spivey and Torrey Wasserman

Articles appearing in Carolina Public opportunities to invest Health may be reprinted with permission from the editor. Send correspondence to Editor, Carolina 51 HONOR ROLL OF DONORS Public Health, UNC Gillings School 53 ROSENAU SOCIETY GIFTS of Global Public Health, Campus Box 7400, 135 Dauer Dr., Chapel Hill, 54 DAUERS HONOR DAUGHTER’S SUCCESS BY PROVIDING SCHOLARSHIP NC 27599-7400. FOR OTHER STUDENTS SUBSCRIBE TO CAROLINA PUBLIC HEALTH 57 SCHOLARSHIP BEQUEST REFLECTS DUNN’S APPRECIATION OF OPPORTUNITIES www.sph.unc.edu UNC PROVIDED HER 25,000 copies of this document were 59 MORSE NAMES OFFICE IN SCHOOL’S RENOVATED ROSENAU HALL printed at a cost of $23,815 or $0.95 60 DAD TAUGHT HER TEAMWORK, MOM TAUGHT HER SCIENCE, per copy. NOW DEVLIN HONORS THEM WITH HER GIFT Carolina Public Health (ISSN 1938- 63 BALCHEM SCHOLARSHIP SUPPORTS NUTRITION STUDENT’S CHOLINE RESEARCH 2790) is published twice yearly by the UNC Gillings School of Global Public 64 GIFTS FROM CORPORATIONS AND FOUNDATIONS Health, Campus Box 7400, University of North Carolina at Chapel Hill, 67 FRIENDS MAKING A WORLD OF DIFFERENCE 135 Dauer Dr., Chapel Hill, NC 27599-7400. Vol. 1, No. 5, Fall 2008.

Front cover photo credits: Young girl in rice field by Pathathai Chungyam. Left to right at bottom: Family photo by iStock International, Inc.; Indigenous Mexican woman by Kim Steele; Two 2008 graduates of our School, Kirkland Lynch (left) and John DeMasi, by Linda Kastleman; Man and camel in Agra, India, by Peter Adams. Back cover photo credits: Left to right at top: School children in Beijing, China, by Dr. Peggy Bentley; Elizabeth Simmons, Master’s in Public Health nutrition student at our School, by Linda Kastleman; Ugandan children by © Lisa Marie Albert. Left to right, second row: Spring 2008 Bachelor of Science in Public Health graduates of our School by Will Owens; Mother and child in Mozambique by Isabelle Michaud-Letourneau, MPH; Jeff Nguyen, Master of Health Care Administration at our School, by Linda Kastleman. Bottom right: Granddaughter hugs grandpa by iStock International, Inc.

2 | VOL.1 • NO. 5 FALL 2008 from the Dean’s desk

wrote this flying over the Cascade Mountains, going home from I the annual Association of Schools of Public Health Deans’ Retreat in Vancouver, B.C. The mountains are grand, majes- The most significant application of the Gillingses’ tic, awe-inspiring in scope and size — a natural gift is funding Gillings Innovation Laboratories metaphor for the challenges facing public health. (GILs) to solve problems in North Carolina and Our 40 (and growing) accredited schools of public around the world. I am so excited about the poten- health share a grand mission to improve the public’s tial of these projects to accelerate solutions to public health across the U.S. and around the world through health problems. (Read more about these projects our teaching, research and service. Our task’s scope and their leaders on page 26 or visit www.sph.unc. is huge and complex— to understand infectious and edu/cph/weblinks.) chronic diseases and halt the spread of these dis- Their work includes: eases, reverse the obesity epidemic, develop and I new vaccines for children, using models that apply effective prevention strategies, assure access to could change vaccine production; health care, eliminate health disparities, deliver safe I portable tools to monitor air pollution; water to all the world’s people, improve our global I models and methods to address the rapidly rising environment and more. These are huge mountains, number of mental health problems in North but so is our determination! Carolina; We in public health are optimists. Armed with I advanced statistical science in clinical research to knowledge, effective interventions and powerful quickly move it forward into clinical and statistical partnerships, we can—we will—make the world practice; DR. BARBARA K. RIMER better, safer and healthier. I state-of-the-art laboratories, methodologies and Several public health deans were interviewed for biomarkers to detect adverse effects of chronic this issue. I thank them for their wisdom, insight exposure to arsenic; and and collegiality, and encourage you to read their I public health impact of moving toward a local, perspectives about the future. As deans, we are com- sustainable food system. mitted to improving the public’s health. These projects don’t end with discovery. We will Changing the world requires huge resources. use our new knowledge to improve the public’s National Institutes of Health funding has fallen pre- health while training our students to be the next cipitously, and it is becoming more and more diffi- generation of public health leaders and problem- cult to be funded. North Carolina’s state budget sup- solvers. Every project will have specific outcomes ports about 18 percent of our School’s costs — pri- for which teams are accountable. It is not enough to marily faculty salaries. These sources are insuffi- dream; we also must deliver. cient to meet all our needs. While we aim to move mountains, our feet are I am so grateful to Dennis and Joan Gillings for planted firmly on the ground where so much work their unprecedented and generous gift, one that per- must be done—in North Carolina and around the mits us to soar in search of scalable solutions to pub- world. lic health problems. Their generosity is grounded in As our School adds their name to ours, we cele- their personal connections to our School — he, a for- brate the Gillingses’ generosity and the wonderful mer biostatistics professor, and she, a former staff people they are. In this issue, we also celebrate and member in the department. They understand the honor the many donors who have enabled the size and scope of public health challenges. And as School to fund scholarships, professorships, rooms, transnational citizens, they know that most health research and so much more. The higher we climb, problems transcend national borders. They, as we, the farther we can see, and the more we can do. are immersed in and committed to North Carolina. Yet, as Dr. Leah Devlin, our N.C. State Health Director, has said: we all are global citizens. It is no contradiction to be both local and global citizens.

CAROLINA PUBLIC HEALTH | 3 features & news

The Public Health Landscape: Challenges and Opportunities

BY KATHLEEN KEARNS • PHOTO BY ELENA LEBETKIN ZANZIBAR, TANZANIA

“The landscape of public health is complex and rapidly emerging. We must bring safe water to over one billion people around the world and stop changing. The challenges are unprecedented. But this the obesity epidemic in its tracks, provide malaria-preventing nets to millions of people landscape also reveals a spirit of global solidarity, and a and increase access to cancer screening, break down disparities in health between strong desire for fairness in health. And this gives us people but find cost-effective ways to deliver services. It’s not a question of one or the an occasion for unprecedented optimism as well.” other. The challenge of 21st century public health is to prevent where possible and treat —Dr. Margaret Chan, Director-General of the World Health Organization (WHO) when necessary, learn from the past but cre- From a speech given in Singapore on April 3, 2007: www.who.int/dg/speeches/2007/030407_whd2007/en/print.html ate new solutions based on the knowledge, tools and technologies available to us today, hirty years ago, most public health “My professors in the 1970s proclaimed create new knowledge but apply evidence- professionals had declared victory that infectious diseases were behind us, and based solutions, where possible, and to do over infectious diseases and were the future of public health would be wrapped this in our backyards and around the world. wagingT war against the chronic conditions up in chronic diseases,” says Dr. Barbara K. Perhaps never have the challenges been they believed were the biggest health threats Rimer, dean of the UNC Gillings School of greater and the opportunity for impact more of the future. The language of health often Global Public Health. “We were wrong! The immense.” took on the semantics of war as the U.S. old problems have not gone away. In fact, Resurgence of tuberculosis in multi-drug- fought the “war on cancer” and communities they’re back with a vengeance, along with resistant form, along with outbreaks of organized themselves to tackle cardiovascu- some calamitous new ones, like AIDS. So we measles and whooping cough, join newer lar diseases. face the challenges of the old, new and infections, such as drug-resistant intestinal

4 | VOL.1 • NO. 5 FALL 2008 THE PUBLIC HEALTH LANDSCAPE: CHALLENGES AND OPPORTUNITIES

“superbugs,” HIV/AIDS and Avian flu as major threats to health worldwide. Disaster preparedness has been added to “Perhaps never have the challenges been greater the list of resurgent public health challenges. Not only did the events of Sept. 11, 2001, and and the opportunity for impact more immense.” the subsequent anthrax attacks reveal the need for a new level of disaster preparedness Dr. Barbara K. Rimer • Dean, UNC Gillings School of Global Public Health and training; Hurricane Katrina exposed severe shortcomings in current prepared- developed countries. These poor health out- use in the United States is the greatest single ness planning for comes are very big challenges for us all.” public health success of the last half-century natural disasters. in terms of lives saved, yet it remains the sin- “The whole pic- Unprecedented challenges gle leading cause of avoidable premature ture has shifted quite Public health leaders point to a wide range of death, not only in our society but increasing- dramatically,” Rimer pressing problems. They include, in no par- ly in developing countries,” says Dr. Kenneth says. “As Marcel ticular order: Warner, dean of University of Michigan’s Proust reminded us, OBESITY: “Today, over 1.6 billion indi- School of Public Health. Dr. Barbara K. Rimer we must see the land- viduals are overweight or obese, diabetes and SANITATION: Dr. Margaret Chan, WHO scape with new eyes. The world is smaller, and heart disease rates are skyrocketing and qual- Director-General, has noted that sanitation many of the distinctions between chronic and ity of life is being diminished for many glob- has a vital role in promoting health, dignity infectious diseases are overly simplistic.” ally,” notes Dr. Barry Popkin, professor of and development, while lack of sanitation In North Carolina, public health profes- nutrition in the UNC schools of public health breeds disease and anchors huge numbers of sionals face the challenge of the state’s low and medicine and director of UNC’s people in poverty. About 1.1 billion people standing on many health indicators. Interdisciplinary Obesity Center. “Mexico’s around the globe lack access to an improved “Whether you pick childhood obesity or obesity rate equals ours, and its diabetes rate water supply—approximately one in six peo- infant mortality or years of life lost—for any soon will be above ours,” he adds. ple on earth. Additionally, 2.6 billion people measure you pick—we rank very poorly in “Economically, the costs are great. For exam- worldwide—3 times the U.S. population— national standings,” says N.C. State Health ple by 2025, nine percent of China’s GNP will lack access to improved sanitation. The June Director Leah M. Devlin, DDS, MPH. “And go toward obesity-related economic costs.” 28, 2008, issue of The Lancet includes an edi- the U.S. doesn’t rank very well against other TOBACCO USE: “The decline in tobacco torial that calls for an immediate global action plan to expedite improvements in water, sanitation and hygiene and reflects on the new WHO report—Safer water, better health. The WHO report, published in June 2008, concludes that 9.1 percent of the global burden of disease could be prevented by improving water, sanitation and hygiene. In 32 worst-affected countries, this figure is 15 percent. (For more information, see www.thelancet.com/journals and www.sph. unc.edu/cph/weblinks.) MENTAL ILLNESS: “Some of our mental health problems (in the U.S.) are due to the fact that, until this year, even people with good health insurance coverage were denied adequate coverage for mental health condi- tions,” says Dr. Patricia Wahl, dean of University of Washington’s School of Public Health. “The return of the military serving in Iraq with post-traumatic shock will further raise awareness of mental health issues in need of public health solutions.”

CAROLINA PUBLIC HEALTH | 5 features & news

GENETICS: A host of legal, medical and P. Evans, professor of genetics and medicine have various disease predispositions and that ethical questions has arisen around the bur- in UNC’s School of Medicine and director of we have the capacity to engage in truly preven- geoning availability UNC’s cancer and adult genetics clinics and tive medicine because of genomic advances, of information about the Bryson Program in Human Genetics. “The will serve as further inducements to pursue individuals’ genetic public health arena will be critically important broadly-pooled risk and universal access to makeup. “Rightly or as health care and genetics become further medical care.” wrongly, individuals intertwined,” Evans adds. “In fact, many of the accord their genomes major advances in risk prediction and geneti- Double-edged sword a special status and cally-guided treatment will have their most of “progress” consider it worthy of salient influences in the context of public These and other public health concerns exist unique protections. health. Indeed, the emergence of genetic med- in the context of — and often are caused or Dr. James P. Evans As we move forward icine, with its illumination of a myriad of rela- influenced by— worldwide developments, with attempts to use genetic information for tively subtle genetic risks for common diseases such as globalization and urbanization, both the betterment of health, it will be a challenge shared by the entire population, could trigger of which have had to protect the individual’s privacy while a dramatic shift in the way we deliver health tremendous impact affording necessary access to it,” says Dr. James care in the U.S. The recognition that we all on health and on the profession of public health. Other problematic trends include: POPULATION GROWTH: The Dr. Michael Klag fundamental prob- lem underlying issues like safe water, envi- ronmental pollution, food availability and climate change is population growth, says Dr. Michael Klag, dean of Johns Hopkins University’s Bloomberg School of Public Health. “If we don’t slow population growth, these problems will all get worse.” WIDENING HEALTH DISPARITIES: On every health indicator, there are enor- mous racial, cultural and geographical dis- parities in North Carolina, says Devlin, of the N.C. Division of Public Health. The challenge of equal access to health care is mirrored globally, notes Dr. Barry Bloom, dean of • PHOTO BY JEANETTE LAGER Harvard Univer- sity’s School of Dr. Barry Bloom Public Health. “The

LHASA, TIBET fundamental issue I’m most concerned about, looking forward, are the increasing disparities in health within and between countries,” he says. “I am concerned that at some point it may lead to a great deal of social disruption.” INADEQUATE EMPHASIS ON PRE- VENTION: Determining how to increase

6 | VOL.1 • NO. 5 FALL 2008 THE PUBLIC HEALTH LANDSCAPE: CHALLENGES AND OPPORTUNITIES

investment in and commitment to health storms and tidal waves. “The impacts are talk with police promotion and disease prevention is a going to occur not only, but primarily, in departments, fire longstanding public health conundrum. areas around the equator where temperatures departments, faith- “Prevention is a far less costly approach,” are higher, and these tend to be developing based organizations Devlin notes. “The cost of health care in this countries,” he notes. and others. We also country is over two trillion dollars, and by have to make our 2016, that will dou- Reasons for optimism leaders aware that ble.” Just one percent In the face of these multi-layered challenges, when public health of that figure is spent public health leaders have developed evi- is affected, the pro- Dr. Joxel Garcia on prevention. “We dence-based strategies that have promise. ductivity of our nation is affected.” just can’t afford to Almost all agree that interdisciplinary part- Local public health departments play a keep going down the nerships are critical, as are alliances with sec- critical role in convening the community and road we’re going.” tors that traditionally have not been explicit- fostering collaboration among multiple AGING POPU- ly involved in public health. sectors, says North Carolina’s Devlin. “The LATIONS: Due to Dr. Leah Devlin the success of past public health efforts, the population in the “Effective public-private partnerships U.S. and around the world is rapidly aging, and that is creating unprecedented demands can bring communities and public health on health care systems. “We now have people organizations into a better alignment of shared working in their late 70s and early 80s, and very productively,” says U.S. Assistant goals and shared efforts.” Secretary for Health Joxel Garcia. “We have to help the people manage their diseases and Dr. Julie Gerberding • Director, Centers for Disease Control and Prevention have a good quality of life.” POVERTY: Overcoming poverty is “absolutely critical and something we haven’t “We have to use the resources that we have reality is that these issues are very figured out how to do,” says University of in the most efficient and effective way that we complex, very important and are everybody’s Michigan’s Warner. “We’ve got loads of data can,” says Dr. Julie Gerberding, director of the shared responsibility. But someone’s got to that indicate that, when you look at health national Centers for Disease Control and convene (the various partners) and provide status and control for other factors, poverty Prevention (CDC). “Partnership becomes the leadership and still stands out independently as a tremen- very important when resources are tight. the infrastructure dously important influence on health. That’s Effective public-private partnerships can so that the entire going to be a huge challenge for the future.” bring communities and public health organi- community can CLIMATE CHANGE: Global warming zations into a better alignment of shared contribute to the has resulted in deadly heat waves, outbreaks goals and shared efforts. ‘stone soup’ strate- of cholera and Rift “Businesses are probably the most aligned gic to improve Valley fever, and the with public health in some sense,” she contin- health.” spread of dengue ues. Many provide health insurance to Policy changes Dr. Patricia Wahl fever in the south- employees, so they recognize the high cost of are among the most ern United States, to health care for chronic disease. “It makes powerful interventions to change behaviors cite just a few exam- business sense to invest in wellness and and promote health, public health leaders ples. Dr. James health protection up front. They’ll have a point out. “We fought for years and years to Merchant, former healthier, happier, more productive work- encourage people to use their seatbelts, but dean of the Univer- force, but also healthier, happier families and we didn’t get a good usage rate until we Dr. James Merchant sity of Iowa’s Col- ultimately a more healthful community.” passed a law,” Washington’s Wahl says. “In lege of Public Health and now professor of Public health leaders “have to realize we smoking, there was a lot of work in behavior occupational and environmental health at the can’t do it by ourselves,” adds Garcia, the U.S. change, but probably one of the most effec- college, predicts significant further impact— Assistant Secretary for Health. “We have to tive things is that there will be no smoking in greater famine because of temperature rise, move away from the silo mentality and work public places and eating places (in her home difficulties with crop production, challenges as a system. We need to bring in the business state of Washington).” Similarly, encouraging to water supplies, more frequent severe sector, transportation, education. We have to children to drink milk and water instead of

CAROLINA PUBLIC HEALTH | 7 features & news

sodas “apparently did little good until we got the schools to remove soft drink machines.” International agreement on policy change provides a promising model as well. Michigan’s Warner is encouraged by the WHO Framework Convention on To- bacco Control, a treaty put into effect Public health leaders “have to realize we can’t do it in 2005 and ratified to date by more than by ourselves. We have to move away from the silo 150 countries (al- Dr. Ken Warner mentality and work as a system. We need to bring though not the United States). It established ways to reduce in the business sector, transportation, education.” cigarette smuggling, banned tobacco adver- tising and sales to children, and called for Dr. Joxel Garcia • U.S. Assistant Secretary for Health higher prices, among other measures. “Since U.S. Department of Health and Human Services its inception, WHO has had the authority to mount global health treaties and had never used that authority until now,” Warner says. a society where tions in infant mortality. (See www.sph.unc. He sees the treaty as an example that the health is the default, edu/cph/weblinks.) global community could follow to solve other where everyone has “If someone had said to me in 1994 that problems as well. the opportunity to today we would have a dozen countries Another strategy for improving public experience the won- around the world that do not allow smoking health—one pioneered in North Carolina derful things in life in any workplace, including all bars and and managed by our School’s North Carolina that good health can restaurants, I’d have said you were crazy,” Institute for Public Health—is accrediting enable. And we need Michigan’s Warner says. “The fact is we do local health departments to ensure quality. Dr. Julie Gerberding to regard that as a make progress. If you look at what we’ve “Some are talking about (more widespread) national priority just as we regard other achieved over the last century, the problems certifications and accreditation,” the U.S.’s strategic national investments like our that confront us are Garcia says. “I think we have to use all of Department of Homeland Security and our big, but they’re not (these strategies) to empower our workforce. Department of Defense.” necessarily more It doesn’t matter if it’s a state public health intimidating than officer, a communicator in a federal agency, a Creating a more equitable those that confronted policymaker or an epidemiologist, we need to world for health us 100 years ago.” empower all of them with processes that will Though the challenges facing public health Public health is an allow them to be the best they can be.” may appear daunting, leaders like Margaret exciting, stimulating Even as new tools and strategies are con- Chan at WHO are optimistic. “We see signs of and rewarding ca- Dr. Jim Curran sidered, public health’s long-term emphasis a shared desire for a more equitable world for reer, summarizes Dr. on prevention is gaining new traction. health opportunities and outcomes, and of Jim Curran, dean of Emory University’s “Health is a very precious resource these shared responsibility in making this happen,” Rollins School of Public Health. “The mis- days,” the CDC’s Gerberding says. “If we don’t Chan said in an April 3, 2007, speech in sion itself is both challenging and noble— do more to invest in protecting health, we will Singapore. “It’s a time of unprecedented inter- trying to improve the health of others—and never be able to afford to restore it once we’ve est in health. Our cause is supported by a it’s so interdisciplinary and diverse,” he says. lost it. Our system has got to change dramati- growing number of health initiatives, imple- “Its success depends on working with people cally and put a much greater premium on menting agencies, public-private partnerships, from different intellectual backgrounds and investing in keeping people healthier and foundations, funding agencies and rock stars.” cultural backgrounds from your own. There’s helping people who are at risk return to a state Other public health leaders point to the a lot of learning that must be done to succeed, of lower risk and better health. CDC’s tally of the great public health success- and when you do succeed, not only do you “We need to really help our citizens and es of the last century, which includes dramatic achieve the noble mission, but the sum is our decision makers understand that we need improvements in life expectancy and reduc- always much, much greater than its parts.” I

8 | VOL.1 • NO. 5 FALL 2008 GILLINGS GIFT

Gillings Gift positions UNC to better meet and practitioners in tackling important and practical research issues in clinical trials.” 21st century public health challenges Another project already funded through the Gillings gift will look at ways to improve North Carolina’s mental health services. The critical problems of providing mental health care are not unique to North Carolina—and finding better ways to provide care here will be useful across the U.S. and throughout the world. (See page 31.) “Improving mental health services is one of the biggest public health challenges facing North Carolina today,” says Dr. Joseph Morrissey, UNC professor of health policy and administration. “Our GIL will link Carolina and Duke faculty with community Dr. Joseph Ibrahim Dr. Joseph Morrissey Dr. Ralph Baric partners to work on ways of improving the mental health system using computer simula- hroughout its nearly 70-year histo- “The enormously generous gift from tion and other decision-support tools.” ry, the University of North Dennis and Joan Gillings is giving us the Our School’s new name—the UNC Carolina’s School of Public Health resources and freedom to tackle some of the Gillings School of Global Public Health— Thas aggressively confronted public health world’s biggest public health challenges quick- recognizes the transformational gift made challenges as close as Carrboro, N.C., and as ly, our way, with colleagues from across the possible by two people with strong ties to the far away as China. UNC public health faculty School, University, state and world,” says Dean School who feel passionate about its work. members, staff and students have built the Barbara K. Rimer. “Their gift will enable us to (See their stories on pages 10 and 14.) School into one of the top research and teach- accelerate our impact in solving public health “The words global public health reflect the ing facilities in the world addressing areas problems and educate students using these fact that all public health is global, and that such as water quality, nutrition, cancer new paradigms—and that’s why most of us global health is public health,” Rimer has screening, clinical trials and infectious dis- chose public health as our life’s work.” said. “We are fully committed to North ease control. Researchers who already have received Carolina and its citizens, and we recognize One of the distinguishing features about Gillings funding for projects explain the the interconnectedness of all people in our School is a strong emphasis on applying importance of these grants. today’s world.” research to solve real-world problems. U.S. “Funding for the Gillings Innovation Labs Rimer explains that about 18 percent of News and World Report consistently has rated (GILs) serves as a novel platform for develop- School expenses are covered by the state of UNC the top public school of public health ing key early-stage technologies for improv- North Carolina. “We are grateful for this since the magazine began its ratings in 1990. ing human health outcomes across the globe,” funding,” Rimer says. Much of the money for Overall, UNC ranks just behind the Johns says Dr. Ralph Baric, epidemiology professor research comes from competitive federal Hopkins Bloomberg School of Public Health and principal investigator of a project grants for specific projects, but the federal and is tied for second place with the Harvard designed to find a single-dose vaccine for res- budget for health research is shrinking dra- School of Public Health. piratory diseases that’s easy to store and matically and many fewer grants are being To remain a top school of public health, administer. If successful, the vaccine could awarded. we must address the enormous public health save millions of children’s lives in developing “Dennis and Joan Gillings have made it challenges of the 21st century. As infectious countries. (See page 32.) possible for our world-class School to serve diseases reemerge, as gaps caused by health “The Gillings gift has, among other things, our friends and neighbors across North disparities widen, as pollution threatens the really enabled us to bridge the gap between Carolina and around the world with stronger quality of air and water, we must ask hard academia and industry in clinical trials research, educational and outreach pro- questions, work even harder to solve public research,” says Dr. Joseph Ibrahim, Alumni grams,” Rimer says. “Meeting the challenges health problems in North Carolina and Distinguished Professor of biostatistics and of the 21st century is a daunting task, but this around the world and educate the next gener- principal investigator for the UNC Center for gift strengthens our ability to anticipate ation of public health leaders. Innovative Clinical Trials. “It has facilitated public health problems and accelerate their That’s what makes the gift from Dennis an unprecedented new form of dialogue and solutions.” I and Joan Gillings so important to UNC. collaboration between academic researchers — BY RAMONA DUBOSE

CAROLINA PUBLIC HEALTH | 9 features & news

Dr. Dennis Gillings joined the UNC Department of Biostatistics faculty in 1971 and began his early teaching career with fellow assistant professor, Dr. Gary Koch, in what was known as “Trailer 39.” The trailer was one of three makeshift offices set up in and around parking lots behind Rosenau Hall on the Carolina campus. Gillings served on the School’s faculty until 1988. He is now chairman and chief executive officer of Quintiles Transnational Corp.

Drawing strength, experiencing success, now returning to his roots

Wait. Ballroom dancing? r. Dennis Gillings is clearly a man of intent. From the age of 15, when his mother said it That is, he intends to excel at everything he “is good to be able to dance,” he attended the D Morris J. School of Ballroom Dancing. When he went to university, he enrolled in a compet- does, whether he’s running an international clinical itive ballroom dancing class and soon cap- tured the championship. research company, pushing protégés to greater “Well,” he says with a shrug, “I worked hard at it.” heights of accomplishment, staging a “pig pickin’” The 64-year-old London native, a former professor of biostatistics and now chairman or competing in ballroom dancing. and chief executive officer of Quintiles Transnational Corp. (and also Commander of the British Empire, or CBE), works hard at everything he does, propelling himself and those around him to succeed.

10 | VOL.1 • NO. 5 FALL 2008 DRAWING STRENGTH, EXPERIENCING SUCCESS, NOW RETURNING TO HIS ROOTS PHOTO BY TOM FULDNER

“He has a huge amount of intellectual That openness is not often found in the that other people can be successful, and he energy, and especially for graduate students, competitive atmosphere of academia, says can help them, and he can be successful, too.” he is the type of professor who pushes you Douglass, now chairman of the Department That philosophical thread runs through and really helps you figure out your career,” of Oral Health Policy and Epidemiology at his business practices, as well. UNC President notes Julie MacMillan, MPH, a former stu- Harvard University’s School of Dental Emeritus Bill Friday, who calls Gillings “the dent who now heads Carolina Public Health Medicine. He says that when he arrived at great American success story,” notes that the Solutions at UNC’s School of Public Health. Harvard, a senior professor cautioned that global business leader hires those with As a teacher, Gillings was known for being when you teach students all you know, you strengths he needs to round out his manage- enthusiastic, thorough and generous. risk competition from them in the future. ment team. “He’s not just generous with his (financial) “There are people who draw a line around “He gets good people and turns them donations, he’s generous about sharing his how helpful they are willing to be with other loose,” Friday says. “If you are smart enough knowledge,” says Dr. Chester W. (Chet) people, but he (Dennis) doesn’t draw that to pick people smarter than you in their areas Douglass, a former colleague of Gillings’ at line,” Douglass says. “It must have something of expertise, and give them wings to help UNC. “Back when we were assistant profes- to do with his own confidence in his ability to them succeed, you will succeed, also.” sors and he’d be consulting, he would just put information together and not be worried While Gillings easily serves as mentor to give away his knowledge.” for his own goals. He seems to understand many, he does not easily name anyone who

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pushes him to succeed, in return. It soon ters” skittering about when the lights were becomes apparent that Dennis Gillings push- turned on at night. es himself. And he seems genuinely baffled But from this humble space—which Koch that any human being would not want to and Gillings shared with research assis- reach his or her potential—it’s a given with tants—the seeds of Quintiles were sown. It him. began when Gillings was asked to write an “I guess it’s just a competitive or natural expert report for Hoechst regarding a dia- instinct to reach your potential, so when I see betes drug, and Koch reviewed his work. The some great potential in someone and they are two always have had a good rapport, says not realizing it, I challenge. That’s the way I Douglass, who remembers having lunch with am,” he says. the two assistant biostatistics professors in Chapel Hill’s Zoom Zoom Room during his A Global Vision for Business first week on campus as assistant professor of Gillings’ early life is not rooted in the health policy and administration. University of North Carolina, but his profes- “I came home that day and said (to my sional life is. Born at the end of World War II, wife), ‘I am not sure, but I think I had lunch Gillings was educated in the inner city of today with two geniuses,’” Douglass says. London before attending the University of “They had a very high level of ability of com- Dennis Gillings, 1971 Exeter for a bachelor’s degree in mathemat- municating with each other conceptually and ics. He then headed to the University of mathematically, and it clicked like crazy. And use it as a way to hit an approach to a prob- Cambridge for a diploma in mathematical look what they went off and did!” lem in public health. So that way, it became statistics (equivalent to a master’s degree), What they did was catapult a consulting something really practical.” and returned to Exeter to teach while work- business into an organization with astonish- He also took that approach in the business ing on his doctorate. ing global reach. Koch continued to teach but world, says Dr. Lisa LaVange, who was a vice president in the clinical development area at Quintiles before her current job as professor “He drew his strength here, he succeeded, of biostatistics in the School of Public Health. LaVange earned her PhD in biostatistics from and he has turned back to his roots. He is a man UNC. Although she never had a class with Gillings, she considers herself an “adopted of exceedingly good will, and this university will Trailer 39 student.” “He absolutely was a visionary. I don’t be much in his debt for a long time.” remember anybody thinking about global meetings like he did,” she says. “Seeing what Bill Friday • UNC President Emeritus he did in other countries, I became more aware of how everybody interconnected. He is an unbelievable businessman, quite Upon graduating, Gillings and some served on Quintiles’ board of directors while brilliant.” friends decided to head to Africa via Land the company soared, from operating with a Rover for an adventure, but about this time, small, part-time staff in 1974 to its current A meaningful gift one of his statistics professors at Exeter, Dr. reach of 20,000 employees in 57 countries. In a letter to School alumni describing why John Ashford, suggested he think about That’s in part because Gillings used his they gave this gift, Dennis and Joan Gillings teaching in the United States. During a con- classroom abilities to good effect in the board outlined their vision by inviting alumni and ference in Germany, Gillings met Dr. Bernard room. He always had a knack for helping stu- others to “join us in the remarkable journey Greenberg, then chair of Carolina’s Depart- dents understand their work from a human to transform the way public health solutions ment of Biostatistics, who offered him a job perspective, says MacMillan, who calls him are developed and delivered—at home and at UNC. “far and away, the best professor I had at around the world.” Gillings came to UNC in 1971 and began UNC.” Clearly, the donation is intended to propel his early teaching career with fellow assistant “He had this terrific ability to pick up on the School of Public Health, which already professor, Dr. Gary Koch, in what was known your classroom subject and make it real,” she trains some of the best public health students as “Trailer 39.” The stories about the trailer says. “For instance, when presenting some- in the country, toward making a difference are legendary, including descriptions of “crit- thing that can be dry, like biostatistics, he’d on a global scale by engaging students,

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faculty, government, business leaders and trials,” the couple wrote. “We wanted to be be used in a focused and effective way. others in collaboration. a part of the solutions to these and other That is why the School is establishing Friday agrees that the gift will create wide- problems.” competitively selected Gillings Innovation spread, meaningful results. Gillings suggests focusing efforts on spe- Laboratories (GILs), which will focus on “This is the greatest opportunity any cific areas rather than taking broad swipes at major public health concerns. (See page 29.) school of public health has ever had,” he says. public health problems. LaVange sees the gift and the Gillings “First, it will do things to help prevent people “In the United States, public health can’t be Innovation Labs as something that “can and from becoming sick in the first place, and it pushed without good business models, which will have reach, tremendous reach” because will stimulate all kinds of research projects.” is what the focus areas give us,” he says. “It’s a they will emphasize health outcomes and will The research projects will lead to solu- change from 50 years ago, when you identi- seek solutions to a variety of public health tions, a compelling purpose behind the gift. fied the need and then spent money on it.” issues, including environmental problems, “We believe that public health holds the He said he quickly learned that simply water shortages and fetal health. answers to many of the world’s greatest chal- spending money on a problem wasn’t “It’s an opportunity to do research to lenges—from shortages of safe, clean drink- enough. For instance, it’s relatively easy to change the direction of public health,” she ing water, to the growing epidemic of obesity buy and supply vaccines to various regions of says. in this country, to worldwide threats from the world, but if the distribution system For Gillings, it’s all about linking the proj- diseases such as SARS and Avian flu, to breaks down, the vaccines don’t do any good. ect to its impact, or the ultimate outcome. methods for accelerating the speed of clinical Instead, he suggests that his $50 million gift “That is the first step to success, to include a linkage from the project to the impact it’s going to make, to the ultimate outcome or health improvement,” he says. This approach to problem-solving and pushing for meaningful change is nothing new. Douglass recalls that early on, when Gillings was assigned the task of teaching biostatistics to medical students, he wrote a PHOTO BY TOM FULDNER self-instructional text and gave it to them. “It was a way of helping them out that would continue beyond the course, and that’s precisely how he thinks,” Douglass says. “He thinks about ways to accomplish something that will continue on. So it’s not just giving a lecture and being done with it, but thinking about what can come of it afterward. And then what can come of the fact after that? What could I do that would be lasting and meaningful?” The $50 million given by Gillings and his wife, Joan, surely will be a lasting and mean- ingful gift, from someone who traces his pro- fessional roots to a trailer parked outside the School of Public Health in the early 1970s. Friday emphasized Gillings’ loyalty to UNC, calling him a living example of some- one who realized the American dream and provided opportunity to others in return. “He drew his strength here, he succeeded, and he has turned back to his roots,” Friday says. “He is a man of exceedingly good will, and this university will be much in his debt for a long time.” I — BY KIM GAZELLA

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PHOTO BY TOM FULDNER JOAN GILLINGS: Inspiring others with a “can do, hands-on” attitude

ife has been a wild ride for Joan Gillings, and “Maybe the most important trait we have in common is that we’re family-oriented. frankly, she has loved every minute of it. Born Even when he was a full professor at UNC L and starting Quintiles, we had regular in Philadelphia, the daughter of a clothing model evening meals together,” she recalls. It was also at the family dining table, and the president of Whitman Chocolate Co., Joan Gillings says, that Quintiles began. As her husband received increasing numbers of Heckler was reared in Grosse Pointe, Mich. requests to consult with pharmaceutical companies, Gillings worked at a typewriter in After her first marriage ended, she moved It was during those years that she met the kitchen helping administer projects and to Chapel Hill in the early 1970s, believing Dennis Gillings, an up-and-coming faculty organize reports. it would be an ideal place to rear her two member in the department, and their amaz- “Our family and the people he worked young sons. ing partnership began. with believed in Dennis,” Gillings says. “He is From 1974 to 1976, she worked on the “I think what attracts people to each other a man with a vision who believes passionate- staff of the UNC Department of Biostatistics. is shared values,” she says, “and that’s true for ly in whatever he sets out to do. Along the “Even at that time, the UNC School of Public Dennis and me. It’s what has helped us even way, he enjoys what he’s doing.” Health was seen as one of the best in the through rough times. We both have strong Gillings’ direct involvement with Quintiles nation,” she says. “There was a lot going on, a principles, we’re ambitious, we want to ‘grab dwindled when their daughter Susan was lot of excitement.” the ring’ and be the best people we can be. born in 1981. To allow herself more flexibili-

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ty as a working mother, she obtained a real of how Joan’s and Dennis’ insights create new They always had planned a gift to the estate license. She brokered residential and opportunities, new colleagues and innovative School, Gillings says, in proportion to the commercial properties in Chapel Hill training for the next generation of marine gratitude they felt toward biostatistics chair (including one of the office complexes used scientists.” (and later dean) Bernard Greenberg. “Bernie by Quintiles) and around the world, includ- An avid reader, Gillings is interested in found Dennis and believed in him. The ing London, England, and Sydney, Australia. history and the arts, and has contributed School gave Dennis the tools to achieve what Through the years, the Gillingses have knowledgeably as a board member for the he wanted, and he succeeded by taking the shared a philosophy about “giving back” North Carolina Museum of Art, the opportunity that was given. some of their good fortune. In fact, Dennis Wrightsville Beach Museum of History, “We also believe in the mission of the Gillings says his wife took the lead in family Wilmington’s Opera House Theatre School. In our own lives, we value health— philanthropy, calling her his “human side.” Company and the UNC-Chapel Hill we don’t smoke; we’re active and watch how “People call us all the time to be on one Morehead Planetarium. we eat; we believe in preventive care. We board or another,” she says. “But I won’t serve unless I can be a contributing member. And given that I stay busy, I can only commit to “Joan values innovation and collaboration, being active for causes that I value.” Still, the beneficiaries of Gillings’ philan- and she’s determined to get things done. Her thropic efforts are many. She values educa- tion and, as chair of the Board of Visitors of can-do, hands-on attitude is very inspiring.” the University of North Carolina at Wilmington (UNC-W), has worked to create Rosemary DePaolo • UNC -Wilmington Chancellor scholarships for deserving students there, particularly minority students, who could not otherwise afford to attend. She created a fund to support UNC-W’s think this awareness about health and ability “Joan Gillings has made such a difference creative writing program, one of five recog- to be healthy should be available to people in on our campus,” says UNC-W Chancellor nized by The Atlantic (July 2007, www. North Carolina and around the world. Rosemary DePaolo. “She doesn’t see obsta- theatlantic.com/doc/200707u/writing- “Perhaps most importantly, we’ve been cles; she sees challenges. Joan values innova- programs) as among the most innovative proud of the leadership of Bill Roper and tion and collaboration, and she’s determined in the country. Barbara Rimer. Barbara has done outstand- to get things done. Her can-do, hands-on “Like great writers, Joan has a wealth of ing work; she’s a real go-getter, and we want attitude is very inspiring.” vision, energy and creativity,” DePaolo says. to do all we can to help her reach the goals And she knows how to make connections. “She wants to help talented people succeed.” she has set for the School.” For example, as a member of the Advisory The Joan H. Gillings Fellowship in Dennis and Joan Gillings’ strong bond, Board for the Center for Marine Science Creative Writing is awarded annually to an based on shared values and mutual love and at UNC-W, Gillings and her husband incoming master of fine arts student at UNC- respect, has reaped rewards for them as indi- arranged a partnership with the National W. “The gift makes a huge difference in the viduals and as a couple. Even with all the busy- Oceanography Centre at University of quality of our program,” says Philip Gerard, ness—most recently related to the renovation Southampton in England to create and sup- chair of the creative writing department. “We of a historic Chapel Hill house and the wed- port a program for student and faculty don’t have deep pockets of money to award ding of their daughter Susan, now an archi- exchanges and research collaborations. incoming students, so Mrs. Gillings’ gift has a tect—there is still time to honor each other. (Joan is chair of the Southampton University much stronger positive impact here than it Gillings smiles when she describes a Development Trust and Dennis is pro- might in a program that needed it less. She recent anniversary, on which she received 30 chancellor of Southampton University.) has always understood and valued what we roses, one for every year of their marriage. Dr. Dan Baden, William R. Kenan do here.” That has happened every year without fail, Distinguished Professor of marine science, The transformative gift Gillings and her she says, since she received a single rose on and director of the Center for Marine Science husband pledged to the UNC School of their first anniversary. at UNC-W, says that Gillings’ “business savvy Public Health in February 2007 is one more “I told you he’s a passionate man,” she has been a cornerstone of her work with us. example—on a larger scale—of supporting a winks. I The Southampton endowment is an example cause in which they passionately believe. — BY LINDA KASTLEMAN

CAROLINA PUBLIC HEALTH | 15 features & news A PLACE

FOI R RIGOR

Since 1949, UNC’s researchers set the pace for the field of biostatistics.

BY ANGELA SPIVEY

oday it’s a given that biostatisticians work At that time, such principles of statistics hand in hand with geneticists, oncologists had been used in agricultural studies, partic- T ularly in the United Kingdom, but not so and drug manufacturers to design studies and much in medicine. Biostatisticians gradually began to carve out the basic tenets for collect- crunch the numbers. But in 1949, when the UNC ing and analyzing data in biomedical research, and Greenberg was right in the Department of Biostatistics was first established, middle of it. He and others in the UNC department laid out many of the ideas that as far as medical research was concerned, biostatis- today still govern the conduct of medical ticians didn’t really exist. research, especially clinical trials. The state of North Carolina’s first depart- “In the first days we were looked on as ers’ respect. We were speaking a different lan- ment of statistics was established at what would interlopers,” says Dr. Jim Grizzle, professor guage: things like ‘randomization’ and ‘uni- become North Carolina State University, and emeritus of biostatistics at Carolina. In 1957, form ascertainment of outcomes,’” Grizzle its founder, Gertrude Cox, recruited when Grizzle started working as a graduate says. “Suppose you’re studying a treatment Greenberg to teach biostatistics at UNC’s research assistant to Dr. Bernard Greenberg, that’s supposed to prevent heart attacks? schools of medicine and public health while he the first chair of UNC’s Department of Well, what’s a heart attack? For your out- was still a graduate student at N.C. State. Soon, Biostatistics, many investigators were skepti- comes to be uniform, all the centers conduct- in 1949, he was the first faculty member cal of biostatisticians and their ideas about ing the trial have to use the same diagnostic appointed to a new department of biostatistics study design. “We had to earn the research- criteria.” at UNC-Chapel Hill. “The two departments

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were sort of viewed as one by Miss Cox, who founded them,” Grizzle says. Students would often take classes at both institutions. Soon after Greenberg was appointed chair, he began to grow the UNC department and the field by obtaining funding for training students and faculty. In 1953 the National Institutes of Health’s National Heart Institute awarded one of NIH’s first training grants to UNC to train students, postdoctoral fellows, and faculty and to bring in visiting faculty. “These training grants came about in part because Greenberg was asked by the NIH to help them evaluate research proposals from scientists,” Grizzle says. “NIH became aware that the proposals needed statistical help in the worst way.” As Greenberg’s research assistant, Grizzle worked on one of Greenberg’s early consult- ing projects—a contract that the National Cancer Institute awarded UNC in 1955 to serve as the statistical coordinating center for the Southeastern Cooperative Cancer Chemotherapy Study Group. This group of 10 medical schools worked together to con- duct clinical trials and test chemotherapy agents for treating leukemia and lymphoma. “Greenberg and I were among the first cancer chemotherapy statisticians,” Grizzle says. The department also began to work on other proj- ects, including a contract to provide statisti- cal services to Veterans Administration hos- pitals evaluating four operations in the treat- ment of duodenal ulcers.

Laying the framework for clinical trials As Greenberg did this early consulting work, he began to publish his ideas for putting A bit later, in 1967, Greenberg chaired a Dr. Bernard Greenberg, the first chair of UNC’s rigor into designing studies and analyzing committee appointed by NIH’s National Department of Biostatistics, chaired an NIH committee in 1967 directed to develop a data in biomedical research. In 1959, he pub- Advisory Heart Council, to come up with a process for conducting large, multi-center lished in The American Statistician the first process for conducting large, multi-center clinical studies. The landmark paper developed by the committee came to be known as the article describing the design and conduct of clinical studies. The paper that committee “Greenberg Report.” The paper, commissioned cooperative field and clinical trials. At the wrote came to be known as the “Greenberg by the NIH’s National Heart Institute (now called the National Heart, Lung, and Blood Institute) same time he was nurturing the people in the Report.” (See page 22 and www.sph.unc.edu/ outlined the way clinical trials should be run. fledgling UNC department. “Greenberg was cph/weblinks.) The report was commissioned like a second father. He had an enormous by the NIH’s National Heart Institute (now impact on my life,” Grizzle says. “I was essen- called the National Heart, Lung, and Blood tially a country boy trying to get ahead. He Institute). kept throwing opportunity in my path, and “It was a landmark paper that basically he did the same for others on the fledgling outlined the way clinical trials should be run faculty.” by the NIH,” says Dr. Clarence “Ed” Davis,

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Dr. Clarence E. (Ed) Davis, circa 1970s

Dr. Clarence E. (Ed) Davis, UNC research profes- sor of biostatistics, was the primary biostatisti- way of doing that. That’s the concept that risk for heart disease, the Lipid Research cian for the 1984 Lipid Research Clinics clinical Greenberg set out. It has allowed the NIH Clinics study. trial— one of the first trials to show that lower- ing blood cholesterol reduces the risk of heart and other research institutes around the disease. Davis served as interim chair and chair world to ask questions that can only be A personal interest of the Biostatistics Department from 1997 answered by very large studies.” In 1972, the Collaborative Studies Coordin- through 2005. The Greenberg report is also cited as ating Center (CSCC) was established, professor of biostatistics at the School who introducing the idea that a formal independ- Greenberg become dean of the School of served as interim chair and chair of the ent committee should monitor data in clini- Public Health, and Grizzle took over as chair department from 1997 to 2005. cal trials as it accumulates and should review of the Department of Biostatistics. Davis Davis explains that up until the ’50s and interim analyses of the data. joined the faculty that year as well, though he ’60s, many studies were small enough that a In 1972, NIH began setting up coordinat- had first met Greenberg almost a decade ear- student recording data in a lab notebook was ing centers to administrate large, multicenter lier during a summer research program. enough. But things got a lot more complicat- trials. One of the first few centers was award- “Bernie (Greenberg) was one of the few ed when researchers began studying the best ed to UNC, with Grizzle as principal investi- people in the school who seemed to value way to treat cancer or prevent a heart attack. gator. Since then UNC’s Collaborative every other part of the school,” Davis says. “Those questions require studying hun- Studies Coordinating Center (see page 22) “We all get involved in our particular areas, dreds or up into the thousands of people to has evolved to take on other issues such as but Bernie was always very interested in all compare therapies and see which ones are design and data management for these large aspects of public health, not just the quantita- better,” Davis says. “When you have more studies. Among other landmarks, the center tive and biostatistics parts. We were all in awe than one school or university collecting data coordinated one of the earliest studies to of him because he seemed to be able to do for a study, you have to have some centralized show that lowering cholesterol reduces the everything well. I call him Bernie now, but

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believe me when I met him walking in the “Prior to that time I had almost no publi- hall, it was always ‘Hello Dr. Greenberg’ or cations,” Quade says. He had been a coauthor ‘Hello Dean Greenberg.’” on a couple of publications with some inves- Greenberg took a personal interest in each tigators in epidemiology —studies in which faculty member. If someone had something Quade had helped analyze the data. But his happen, such as the death of a parent, only methodological publication was his PhD Greenberg would send a handwritten note. dissertation. “I had some ideas but no time to “You wouldn’t even know how he would develop them. But by the time I was done know, but you would get a note,” Davis says. with that award, I had several good papers in Greenberg nurtured the research life of major journals of the field,” Quade says. faculty as well, encouraging them not only to Those included a publication in the Journal of consult with biomedical investigators, but to the American Statistical Association. also advance the field through methodologi- cal research. Dr. Dana Quade, UNC professor Today: data overload emeritus of biostatistics, remembers this More than 40 years after the Greenberg mentoring. He was an associate professor report, UNC biostatisticians still push the Dr. Barry Margolin served as chair of the when, in 1968, he received a Research Career field forward, developing new tools to help Department of Biostatistics from 1987 through 1999 and director of the biostatistics facility at Development Award from the National investigators explore research questions that UNC’s Lineberger Comprehensive Cancer Center Institute of General Medical Sciences. Quade Greenberg probably couldn’t have imagined. from 1989 through 1999. His research specialty was the statistical design and analysis of experi- says he was focused on teaching and never These questions in genomics and other areas ments, particularly studies in genetic toxicology. would have thought of applying for the grant require huge and complex sets of data—and if it weren’t for Greenberg. the need for new statistical methodology to go with them, says Dr. Michael Kosorok, pro- fessor and chair of the department. Geneticists, for instance, use specially- made chips called microarrays to look for pat- terns in genes that could be related to disease. But one microarray can contain as many as 100,000 genes. Biostatisticians at UNC such as PHOTO BY ANGELA SPIVEY Kosorok and Dr. Fred Wright are working to develop statistically valid methods for analyz- ing this “high dimensional” data. UNC faculty also work to quantify images used in cancer studies or neurological stud- ies. Somehow those pictures have to be trans- lated into a meaningful set of numbers. “There are very few biostatistics departments around the country that are investing a lot into brain imaging, but many of our faculty are working on questions such as how to use images to look at the relationship between risk factors for Alzheimer’s and changes in brain structure,” Kosorok says. Biostatistics Dr. Jim Grizzle, professor emeritus of biostatis- tics at Carolina, served as chair of the faculty collaborate with scientists in comput- Biostatistics Department from 1973 through er science and operations research to develop 1987. In the early years of the department, biostatisticians were looked on as “interlopers,” methodologies to analyze such questions. Grizzle says. “We had to earn the researchers’ Designing and analyzing clinical trials still respect. We were speaking a different language: poses many challenges, and UNC is address- things like ‘randomization’ and ‘uniform ascertainment of outcomes.’” ing many of them through the School’s Center for Innovative Clinical trials (see page 29). For example, the field needs better meth- ods for handling missing data, for conducting

CAROLINA PUBLIC HEALTH | 19 features & news

post-marketing safety assessment of drugs, as is, will not be used in practice unless well as methods for determining when to there is software for it,” Lin says. “So stop a trial early, either because of toxicity, in recent years I have devoted more futility or exceptional efficacy. “The main of my time and effort to develop goal of the center is to form collaborations software implementing my new with industry, the FDA, and other academic methods.” institutions to work together to develop new Lin’s methods and computer pro- methods to solve some of these big research grams can be applied to genetic asso- problems,” says Dr. Joseph Ibrahim, Alumni ciation studies, which try to relate dis- Distinguished Professor of biostatistics and eases or conditions to genetic mark- director of the center. ers. For example, his SPREG program Ibrahim studies Bayesian methods, which can be used to do secondary analyses are gaining popularity in clinical trials in case-control association studies, in because they provide sound mathematical which researchers genotype large tools for analyzing data about a problem numbers of people for maybe 500,000 while taking into account information from different genetic markers, then com- previous studies. In most Phase III clinical pare genetic markers in people with a trials (the final step before drug approval), disease such as diabetes to those with- data is analyzed almost in a vacuum, as if pre- out. But researchers often want to use vious studies don’t exist. Ibrahim explains it the same data to analyze how these this way: “Suppose you’re driving a car and genetic markers affect other traits

you come to the same stop sign nine days in such as obesity or height. “If you do PHOTO BY ANGELA SPIVEY a row, and each time the same car doesn’t that with standard statistical meth- Dr. Michael R. Kosorok, professor and chair of stop and crosses the line. The tenth time you ods, your analysis can be very biased,” Lin the Department of Biostatistics at UNC’s School come to that intersection, you’re thinking says. Lin developed a method and the SPREG of Public Health since 2006, has developed meth- ods for using surrogate and multiple outcomes to ‘I’ve seen this guy the last nine days fly program to do those secondary analyses in a increase cost-effectiveness of clinical trials. His work in cystic fibrosis has included being senior statistician on a large randomized trial which led to a change in national policy favoring nationwide newborn screening for cystic fibrosis. The work of UNC's biostatistics faculty is the these areas. Just as physicists have quantum theory, statisticians have their own theory — right mix of theory, methodology, and applied a body of tools and principles they use to construct new methods to be used in applica- research to push the field forward in these areas. ΂ tions. While some biostatistics departments have no faculty at all working on theory, Kosorok says that proving current methods with theory is crucially important as research through the stop sign, I better slow down. valid and efficient way. questions become more complex. That’s the essence of the Bayesian paradigm; Ibrahim says UNC’s department is strong “Things are changing so rapidly that you it says I’m going to use this previous informa- because the faculty’s consulting work feeds really can’t think about the theory all the tion to make my current decisions. But the into their work developing new statistical time, you just have to do something that classical paradigm essentially ignores that methodology. For instance, a biostatistician seems to work,” Kosorok says. “But if we don’t previous information and treats today’s visit will collaborate with oncologists on a pay enough attention to the theory, we may to the stop sign as if it’s your first.” melanoma trial and coauthor their paper in end up coming up with numbers that don’t Most of the faculty such as Dr. Danyu Lin, an oncology journal, then author a paper in a mean as much as we think they do, that don’t Dennis Gillings Distinguished Professor of biostatistics journal about the methodology answer the scientific questions that we want Biostatistics, develop new methodology— developed for that study. Methodology and to answer. So we need to also be thinking the- and computer programs that apply that practice are intertwined. oretically to find the proper way to handle methodology —to take on the ever more Kosorok says that UNC’s faculty work is these new, complicated situations. This is complex problems of genomics. “A new sta- the right mix of theory, methodology, and going to help us in the coming years to set the tistical method, no matter how wonderful it applied research to push the field forward in pace for the field of biostatistics.” I

20 | VOL.1 • NO. 5 FALL 2008 UNDERSTANDING THE PUBLIC

SRU do more actual data collection, while Understanding the Public: Odum has concentrated on training and facilitating the activities of researchers who need population data, Kalsbeek says. The UNC’s Survey Research Odum’s focus also rests more heavily in the social sciences while the SRU mostly deals with health-related research. Unit helps researchers In the last 18 years, the SRU has gathered information that has contributed to approxi- mately 300 research projects, including stud- collect high-quality data ies to: I understand adolescent dating behaviors I find out how many adolescents have been given the HPV vaccine uring his first 10 years as a biostatistics professor at the I evaluate emergency room triage method- ologies DUNC School of Public Health, Dr. William Kalsbeek I measure the prevalence of lower back pain collaborated with dozens of faculty members who relied on his I increase the number of people in parts of North Carolina who eat at least five fruits and expertise in survey research methods to conduct population-based vegetables each day, and research. Over time, Kalsbeek realized that those doing popula- I evaluate ways researchers can help reduce smoking among N.C. teens. tion-directed research needed an on-campus facility to offer a full “We’re always trying to find out what’s range of specialized sampling and data collection services. going on with the population at large,” Kalsbeek says. “Many of them doing telephone surveys other things, people’s attitudes, opinions, The SRU uses telephone interviews as a during my first years at UNC would kind of habits, activities and states of health. By con- primary mechanism to collect data. It main- set up their own seat-of-the-pants opera- ducting these types of assessments, the SRU tains a regular staff of 10 but hires up to 60 tions, get a few phones in an office, hire a few enables researchers to measure and predict temporary interviewers to collect informa- students, then start calling,” says Kalsbeek. health outcomes, as well as evaluate the effec- tion for various projects. It also conducts sur- It was obvious they could use some form tiveness and feasibility of health-related veys online and via regular mail. I of assistance in collecting data, he says. interventions. —BY MARGARITA DE PANO So in 1990, with seed money from the “There are all these experts UNC vice-chancellor for health affairs, the who want answers to their dean of the UNC School of Public Health, research questions but have and the chair of the Department of found no easy way to get Biostatistics, Kalsbeek established the Survey them,” says Dr. Robert Agans, Research Unit (SRU) at UNC-Chapel Hill. SRU study director and ques- Organizationally tied to the Department of tionnaire design expert. “They Biostatistics, the SRU serves the whole uni- know the literature, they know versity. “We’ve worked with departments the instruments, but they need across the entire campus, but especially those data. That’s when they come to in health affairs,” says Kalsbeek, SRU director. us… when they want to do a “We’ve also collaborated with researchers at survey.” Duke, Johns Hopkins and other universities The SRU and UNC’s Odum in the state and across the country.” Institute for Research in Social Collaborative research service is the SRU’s Science provide similar servic- primary mission. It helps researchers better es to the university and com- understand the public by collecting data from munity. Both have adopted random samples of the population, says the university’s three-part mis- Kalsbeek, who specializes in sample design. It sion of teaching, service and DE PANO PHOTO BY MARGARITA gathers information to determine, among research. However, staff at the Dr. William Kalsbeek

CAROLINA PUBLIC HEALTH | 21 features & news

UNC’S COLLABORATIVE STUDIES COORDINATING CENTER Controlling quality, managing data, changing the practice of medicine

BY MARGARITA DE PANO

n 1967, a committee chaired by Dr. Bernard Greenberg, coordinate the whole process, from study design to final delivery of public use datasets.” Ithen chair of the UNC Department of Biostatistics (and The CSCC, part of the UNC Department of Biostatistics, also conducts research to contin- later dean of the School of Public Health), wrote a report for uously improve the way multi-site studies are designed and analyzed. “One of our investiga- the National Heart Institute (now the National Heart, Lung, tors, for instance, has done a lot of research on and Blood Institute) that outlined the way clinical trials should how thousands of data fields involving physi- cal activity— collected via monitors people be run. A major component of the document, which came to wear on their belts— can be reduced to mean- ingful statistics,” LaVange says. be known as the “Greenberg Report,” was the recommendation In compliance with CSCC’s mission, all the learning that comes from organizing the vari- that data produced by multi-site clinical trials be managed by a ous components of clinical trials gets passed “data coordinating center.” (See ) on to students and various scholars. Dr. Ed www.sph.unc.edu/cph/weblinks. Davis, director of the CSCC from 1991 to 1997, says one of the advantages of being Four years after the release of of biostatistics at the UNC School of Public housed within a topnotch biostatistics depart- Greenberg’s report, the UNC Collabo- Health. ment and a topnotch public health school is rative Studies Coordinating Center Trials take place in hundreds of clinical that staff at the CSCC are able to train some of (CSCC) opened its doors as one of the and field centers and involve thousands of the world’s future public health leaders. first such data coordinating centers in patients, LaVange says. At any given time, the CSCC has six to 12 the United States. It operates today “The CSCC oversees the accuracy, quality graduate students from the School working on under the three-pronged mission of and consistency of clinical trial and observa- CSCC projects and using CSCC data for their “improving public health by coordinat- tional study data by ensuring that all clinical or dissertations. Postdoctoral fellows and visiting ing important health research, develop- field sites follow identical procedures, use cor- faculty from other countries collaborate with ing innovative research methodology, rect statistics and publish unbiased results,” the CSCC to write manuscripts. Meanwhile, and providing training in the application LaVange says. “We focus on quality control, CSCC faculty teach in the classroom what of research methods.” providing state-of-the-art data management they learn on the job. “I have taught a course Since 1971, the CSCC has coordinated the and statistical analysis services. At the same for many years on how to design and conduct activities of more than 30 multi-site clinical time, we handle the smallest details of what’s a clinical trial,” says Davis. trials and epidemiology studies in the United involved in organizing a study, such as manag- The training component of the CSCC’s States and other countries, says Dr. Lisa ing meetings, training clinical staff, and devel- mission distinguishes it from non-academic LaVange, director of the CSCC and professor oping protocols and manuals of operation. We data-coordinating centers that provide simi-

22 | VOL.1 • NO. 5 FALL 2008 UNC’S COLLABORATIVE STUDIES COORDINATING CENTER

lar services, LaVange says. While university- arteries) over drug therapy in the treatment 2001 to 2005. Some of its ongoing studies based data coordinating centers are now fair- of a narrowing in the lumen of the carotid include: ly common, CSCC is the oldest such univer- artery; and I Atherosclerosis Risk in Communities sity-based center in existence today. “We’d I Several pioneering trials that monitored the car- (ARIC), like to think we have the advantage in years— diovascular and cerebrovascular health of people in I Longitudinal Studies of Child Abuse and that we have developed cutting-edge process- China, Pakistan, Poland and Russia. Neglect (LONGSCAN), es, and that, in our 37-year history, we have “Today, every person in the world who has I Folic Acid for Vascular Outcome worked on studies that have advanced the heart failure gets an ACE-inhibitor, and Reduction in Transplantation (FAVORIT), practice of modern medicine,” LaVange says. carotid endarterectomy is used as a common and CSCC’s work impacts numerous thera- treatment to prevent strokes,” Davis says. I Randomized Intervention for Children peutic areas but can be felt most keenly in the “The results of these trials have crossed over with Vesicoureteral Reflux (RIVUR). field of cardiology. In March 1984, the center into standard practice.” One of CSCC’s challenges is the competi- published the results of the first major clini- Overall, the CSCC has produced more tive nature of its work. “The CSCC is fully cal trial to show that people can reduce their than 1,000 research publications on cardio- dependent on research dollars,” LaVange risk of heart disease by lowering their choles- terol levels. Shortly afterwards, TIME maga- zine published a cover story titled, Since 1971, the CSCC has coordinated “Cholesterol… and now the bad news,” effec- tively disseminating CSCC’s research to mil- the activities of more than 30 multi-site lions of people worldwide. “We’d like to think we’ve prevented a lot of heart attacks through clinical trials and epidemiology studies in that,” Davis says. the United States and other countries. CSCC also coordinated: I The first clinical trial to show that giving an Angiotensin-Converting Enzyme (ACE) vascular disease, cerebrovascular disease, says. “We have to write a lot of proposals and Inhibitor to people suffering from congestive periodontal disease, kidney disease, respira- win a lot of projects. We cannot afford to heart failure can reduce their mortality risk; tory disease, mental health, child health, and have a bad year.” Meanwhile, securing fund- I The first clinical trial to establish the supe- nutrition and obesity, says Dr. Lloyd ing from the NIH is an extremely competitive riority of carotid endarterectomy (a surgical Chambless, research professor of biostatistics process. “A typical NIH multi-site study procedure that removes plaque from inside at the School, who directed the center from involves funding as many as 20 field sites but only one coordinating center. It can be tough. Dr. Lisa LaVange Fortunately, we are doing very well. Our receipts have grown steadily since 2005.” One sign of this is the CSCC’s recent NIH award to coordinate the Hispanic Community Health Study/Study of Latinos (HCHS/SOL), a prospective epidemiological study of 16,000 Hispanics living in the United States. The project examines the impact of acculturation—adapting to life in a new environment and culture—on the health of this minority population. “The study will be the most comprehen- sive assessment of health ever done in this rapidly growing segment of the U.S. popula- tion,” LaVange says. Study results will be shared with communities involved in the research to help improve public health at the local level. For more information on the Collabora- tive Studies Coordinating Center, visit PHOTO BY MARGARITA DE PANO PHOTO BY MARGARITA http://www.cscc.unc.edu/cscc/index.php. I

CAROLINA PUBLIC HEALTH | 23 features & news A mentor BY ANGELA SPIVEY forLIFE ne of Dr. Gary Koch’s former students remembers tracking on—in one form or another—for the last 40 years,” Koch says. “I got my initial stimulus him down long after her graduation to ask him a statistical O basically while being in a work-study situa- question. In South America at the time, he called her back that same tion with Dr. Grizzle.” But Koch’s statistics talent is all his. “He night—around 1 a.m. Another recalls how his deep voice and practi- was sort of a phenomenon as a graduate stu- cal outlook calmed many a graduate student overwhelmed by endless dent because he was writing papers that were problem sets. Others say they associate Koch not only with solid appearing in Biometrics, which is one of the field’s main journals,” Grizzle says. Koch advice, but with food—potluck parties after long hours of work, his became a faculty member at Carolina even habit of meeting with students at a favorite breakfast or lunch spot, before he’d officially finished his PhD. Koch’s father was a physician, and because his insistence that a meal wasn’t complete without dessert. of that, he says, he had leanings toward pre- ventive health, though he knew science, not Koch, professor of biostatistics, is a alma maters. For him, it’s Carolina basketball medicine, would be his professional path. As renowned researcher who has published some but Ohio State football.) a master’s student at Ohio State, he had of the most cited publications in biostatistics. Maybe Koch devotes himself to mentoring focused on operations research and conduct- But it’s possible he exerts his influence nearly because he so values the people who have ed statistical applications in agriculture and as much through his former students, who influenced him, from the high school teach- education. But in his first semester of biosta- tackle research analysis and design problems ers who showed him that writing was an ana- tistics with Grizzle, he knew this was the field at organizations worldwide. “People all over lytical task not so different from the math at for him. the pharmaceutical industry call him up and which he excelled, to the Princeton professor, “I’ve always been problem-driven,” Koch ask him for advice,” says Sonia Davis, senior Dr. Sam Wilks, who took an hour to talk to says. “I like to see specific situations, have an director of biostatistics at Quintiles Trans- Koch about his research interests and advised understanding of what’s involved in them, national Corp. “Once you’re a student of his, him to head to UNC for his doctorate. and have those drive the methodology work you’re always a student of his.” After arriving at UNC, Koch took a job as that I do.” Koch (pronounced like cook) supports a graduate research associate for biostatistics Koch is tall enough to tower over most current students in many ways, including professor Dr. Jim Grizzle, who asked him to people. He comes across as reserved but is through an endowed fund set up by gradu- work on several problems, including one in affable and has a surprisingly raucous laugh. ates of the department in 2001 to help stu- multivariate categorical data. Categorical He focuses intently on the task in front of dents travel to research conferences. When data are used to track yes or no outcomes, him, whether that’s talking to a student, read- donations are made, Koch matches them up such as whether an infection heals or a ing printouts of his email or giving detailed to a certain amount. He matches travel funds headache is alleviated. Koch’s work with directions about how to get to his office. And for other departments, as well. He does the Grizzle helped widen the scope of statistical he is modest. He points out a textbook he co- same for a similar fund at Ohio State. (He methodology for analyzing such data. “That wrote with former student Dr. Maura Stokes, also divides his sports loyalties between his method became something I have worked now a researcher at SAS, but he doesn’t men-

24 | VOL.1 • NO. 5 FALL 2008 A MENTOR FOR LIFE

tion it’s the best-selling book SAS ever published. “And SAS publish- es a lot of books,” says Dr. Lisa LaVange, professor of biostatistics and a former student of Koch’s. Despite his prominence, Koch tries his best to accommodate bio- statistics students wanting to work in the UNC Biometric Consulting Laboratory, which he directs. The lab, part of the UNC Department of Biostatistics, allows students to acquire career training by working with Koch to design studies and analyze data for UNC researchers in public health and medicine. In the late 1970s and early 1980s, collabo- rations between Koch and Dr. Dennis Gillings, then director of the laboratory, led to the development of Quintiles. PHOTO BY ANGELA SPIVEY Koch and Gillings were thrown together in Dr. Gary Koch on campus, and in the 1980s (top photo) in front of “Trailer 39.” 1974 when Koch and his student research assistants moved from the fourth floor of “the trailer,” as everyone called it, wasn’t just a was president and treasurer, and Koch was Rosenau Hall to “Trailer 39”— one of three place to work—it felt like a family. vice president and secretary. “He made most makeshift offices set up in and around park- In addition to consulting for UNC of the decisions as to how the company was ing lots behind Rosenau on the Carolina researchers, Gillings and his student assistants going forward, but I was the sounding board campus. Gillings and his students already began taking on projects for pharmaceutical as to whether something he was thinking were using one end of the trailer, and when companies such as Hoechst-Roussel. Koch about was a good idea or a bad idea,” Koch Koch and his students moved in, a natural and students would provide computer pro- says. collaboration started. grams they developed or lend expertise on Gillings later became so busy he needed either to reduce his Quintiles activities or pursue them full time. He decided at that “He always takes the students’ interests to heart. point to leave the university, and asked Koch to consider whether he wanted to do the Students know they can go to him and get fair and same. Koch says his decision was easy. Conducting research and working with stu- honest help heading in the direction they want to go.” dents are what make him tick. After Gillings’ departure, Koch went on to Dr. Rebekkah S. Dann • principal biostatistician, GlaxoSmithKline become director of the Biometric Consulting Laboratory, which was founded by Gillings in 1980. He has led the lab ever since. It wasn’t the decidedly unposh digs in methods. “We both tended to peer review Since then, Koch’s student family has Trailer 39 that drew students there, but the what the other did,” Koch says. Koch and stu- grown so large it can be hard to keep track. chance to work with Gillings and Koch on dents also worked on projects for McNeill Just after Gillings left, Koch was supervising real-world problems. “We were in a group of Consumer Products Co. and American Home both his own student assistants and those two professors and probably 10 or 12 stu- Products, the parent company of Wyeth. who had worked under Gillings, so he was dents, back under the trees behind the When Gillings decided to set up an exter- responsible for 17 or 18 students, he says. School. It really felt like our own important nal company to handle the growing workload Davis remembers that even in the 1990s, world,” says Julie Macmillan, MPH, who from pharmaceutical companies, he asked when she worked in the lab, he supervised worked in the lab while pursuing her master Koch to co-found it. “We had such substan- about 20 or 25 students. Today, Koch says, it’s of public health degree in the late 1970s. She tial collaboration on things, so together we about 10. Or maybe it’s 12. “Sometimes,” he is now managing director of Carolina Public did the paperwork to found Quintiles as a laughs, “I feel like the old woman who lived Health Solutions at the School. Davis says two-person company,” Koch says. Gillings in a shoe.” I

CAROLINA PUBLIC HEALTH | 25 features & news
Anticipating Public Health Needs;

26 | VOL.1 • NO. 5 FALL 2008 ANTICIPATING PUBLIC HEALTH NEEDS; ACCELERATING PUBLIC HEALTH SOLUTIONS Accelerating












Public Health Solutions

he UNC Gillings School of Global Public selection of projects for funding,” MacMillan says. The CPHS Acceleration Advisory Health is working with partners across North Committee— comprising experts in the T fields of public health, government, policy- Carolina and around the world to develop new ini- making, foundations, science, business and technology—brings additional perspectives, tiatives that will accelerate solutions to the daunt- skills and expertise to help guide develop- ment of programs supported by the gift. ing public health challenges of the 21st century. Some funds are being invested in endow- ment so the gift will keep funding public “The health challenges we face today are explains MacMillan. CPHS is working with health research and education for generations ones that require interdisciplinary teams School faculty, students and staff as well as to come. Other funds are being put to work working together to solve,” says Julie external researchers and leaders to collabora- right away. The majority of the money is MacMillan, MPH, managing director of tively develop solutions to both emerging and earmarked for Gillings Innovation Labs, Carolina Public Health Solutions (CPHS), an intractable public health problems. or “GILs”—competitively-selected projects organization within the School’s Dean’s “The Dean’s Council and other School focused on solving big public health prob- Office established to lead programs support- leadership are important advisers in the lems. (See page 29.) ed primarily by the gift from Dennis and Joan Gillings and other resources their gift may generate. “Part of the mission of our initiative is to bring together leading public health experts from around the globe in academia, non- profits and the private sector to develop new capabilities that can make an impact on today’s critical public health problems,”

Dr. William Vizuete, assistant professor of environ- mental sciences and engineering, is leading a Gillings Innovation Lab that is using human lung tissue to examine the effects of toxic city air pollutants on human health. PHOTO BY LINDA KASTLEMAN

CAROLINA PUBLIC HEALTH | 27 features & news

“Our project focuses both on health and on chemistry,” says Dr. William Vizuete, assistant professor of environmental sciences and engineering, who recently received GIL funding to study harmful pollutants created in city air. “Unless you have a review panel with the vision to understand the significance PHOTO BY LINDA KASTLEMAN of both areas, then the project can be under- valued. The review panel for the Gillings Innovation Labs recognized not only the value on the chemistry side, but also on the health side, and had the vision to see how the two of these things can come together and produce something that’s better than the sum of its parts.” Kim de Bruijne, a doctoral student in environmental sciences and engineering, Other initiatives funded through CPHS examines human lung cells through a include: microscope. I Gillings Visiting Professorships I The Gillings Prize for Public Health Impact Award (still under development) Santé Publique (EHESP) in France, to in public health. In the coming months, our I And enhanced curricular innovations develop a new school of public health with School will be inviting nominations for this Gillings Visiting Professorships (GVPs) campuses in Paris and Rennes. Ricketts will new award. enhance the School’s intellectual climate by spend between 30 and 50 percent of his time Some curriculum enhancements also will exposing faculty, staff and students to alter- on this project through September 2010. be funded by the gift. “These will be relatively native ways of thinking, new methodologies and different perspectives about public health problems. Gillings Visiting Professorships enhance the UNC Gillings School of Global Public School’s intellectual climate by exposing faculty,

Health faculty may apply for these pro- staff and students to alternative ways of thinking, fessorships, as may leading public health new methodologies and different perspectives experts external to about public health problems. the School. Sheila Leatherman The first GVP was awarded to Sheila Leatherman, research pro- During his two-year assignment, he will small in practice,” says Senior Associate Dean fessor of health policy and management at develop public health courses that can be Dave Potenziani, who leads the faculty com- the School. Leatherman evaluates and ana- adapted to the UNC context, create research mittee developing changes, “but we hope they lyzes health care sys- and teaching opportunities for UNC faculty will have substantial benefits to students.” tems around the and develop a joint research conference The first change is to “globalize” the cur- globe. The GVP will involving EHESP and UNC faculty and stu- riculum. Another change will be to ensure all support her and dents to share mutually useful research and UNC public health graduates emerge with UNC’s efforts in analyses. Ricketts is director of the Policy critical, core financial skills they will need in microfinance and Analysis Program at the UNC Cecil G. Sheps their careers. public health. Center for Health Services Research. For more information on these and other Dr. Thomas Additional GVPs will be announced in the initiatives, visit Carolina Public Health Ricketts, professor of coming months. Solutions’ Web site at www.sph.unc.edu/ Dr. Thomas Ricketts health policy and Funding from the Gillings gift also will acelerate. I management at the School, also was awarded create the Gillings Prize for Public Health —BY TORREY WASSERMAN, a GVP. He is working with French Impact—an international honor to recognize RAMONA DUBOSE researchers at the École des Hautes Études de people who have made a substantial impact AND EMILY J. SMITH

28 | VOL.1 • NO. 5 FALL 2008 GILLINGS INNOVATION LABS

Gillings Innovation Labs focus interdisciplinary
efforts on tough public health problems








Principal investigators must be UNC pub- NC’s Gillings Innovation Labs (GILs) bring lic health faculty members. GIL leaders are together interdisciplinary research groups to encouraged to include students in their proj- U ects. Other collaborators and supporting focus concentrated efforts on solving big public team members may be UNC faculty as well as other experts, including people from govern- health problems. They vary in topic, scope, focus ment agencies, other non-profit organiza- tions and businesses. (See www.sph.unc.edu/ and purpose — but share certain characteristics. All accelerate for detailed guidelines.) strive to be innovative, have impact, and accelerate Project proposals are submitted to Carolina Public Health Solutions, the organi- solutions to public health problems across North zation that, along with the School’s Dean’s Office, administers programs supported by Carolina and around the world. Gillings gift money. The proposals are then reviewed by subject-matter experts through- out the United States and abroad. Their rec- ommendations are reviewed by UNC Gillings School of Global Public Health Dean Barbara



K. Rimer and her team of associate deans, department chairs and internal experts for final funding decisions. “We were delighted by the strong, innova- tive proposals we received for the first com- petitively awarded GILs,” Rimer says. “We’re grateful to the excellent reviewers and to department chairs and other School leaders, all of whom were deeply engaged in the review process. What excites me especially is that each funded project has the potential to solve real public health problems. While some are focused at home and others abroad, they all have potential for broad dissemination.” Some of the currently-funded GILs aim to: I Advance statistical science to provide safer, faster treatments for patients: The Center for Innovative Clinical Trials is devel- oping new statistical methodologies to improve clinical trials of medicines and other treatments in development. The current meth- ods are lengthy and expensive, and still, the tri- als don’t always identify potentially harmful side effects. The Center, led by Dr. Joseph

CAROLINA PUBLIC HEALTH | 29 features & news

Ibrahim, Alumni Distinguished Professor of and/or treatment. Patient data confidentiality tissue to examine the effect of toxic pollutants biostatistics, has an interdisciplinary focus that will be protected and honored in the project. in that air. brings together fac- The UNC Schools of Medicine and of I Develop a local, sustainable food system: ulty from several Information and Library Science are project Dr. Alice Ammerman, nutrition professor and UNC departments partners. “Finding an innovative system to director of the Center for Health Promotion and additional col- link these data repositories so they can be and Disease Prevention, leads this GIL — a laborators from better analyzed and managed could signifi- two-year study to improve understanding industry, who are cantly improve the state’s ability to monitor about health, environmental, and economic engaging jointly in both methodologi- cal and applied research in clinical Dr. Joseph Ibrahim trial design, analysis and dissemination. The “What excites me especially is that goal is to bring better treatments to patients faster and less expensively. each funded project has the potential I Evaluate portable field tests to detect fecal contamination in water: This GIL, to solve real public health problems.” headed by Dr. Mark Sobsey, Kenan Distinguished University Professor of envi- Dr. Barbara K. Rimer • Dean, UNC Gillings School of Global Public Health ronmental sciences and engineering, will develop and evaluate a simple, inexpensive, portable field test to detect fecal contamina-





tion in water. Infectious diseases from fecal contamination of water include diarrhea, and investigate health problems in the popu- issues associated with this growing national dysentery, cholera, enteric fevers, and infec- lation, and speed up timely solutions,” trend. “Among the most pressing public health tious hepatitis. Together, they kill more than Richardson says. “By better mining available problems in the U.S. today are obesity, envi- 1.6 million people a data and managing information, local and ronmental degradation, and health dispari- year and make bil- state medical officials will have more com- ties,” Ammerman lions more people plete information on which to make deci- says. “Contributing sick. “We’re really sions on new policies and allocation of in a big way to each excited to get this resources.” of these problems is research under way I Identify harmful city air pollutants: This our current food and work with our GIL, led by Dr. William Vizuete, assistant system, with its international public professor of environmental sciences and heavy dependence health partners,” engineering at the School, will focus on the on fossil fuels (fertil- Dr. Mark Sobsey Sobsey says. “The measurement of harmful pollutants created izers, pesticides, and ultimate goal is to make simple, reliable tests in city air. Epidemiological studies have gasoline) for large- Dr. Alice Ammerman that will be commercially available to people linked certain air pollution to tens of thou- scale production and long-distance transport around the world within two years.” sands of deaths worldwide each year. Yet, lab- of often high-calorie, nutrient-poor food.” I Find ways to link, analyze, and manage oratory toxicology studies of these same pol- Among other things, this project will help large electronic data repositories: Dr. David lutants show few health effects at levels seen determine whether current consumer interest Richardson, assistant professor of epidemiol- in the ambient air. What is missing in these in locally-grown food can create an economic ogy at the School, is leading this GIL, which studies, says Vizuete, are the harmful pollu- environment supporting small to mid-sized is focused on the development of innovative tants that are created in the air. These typical- farms as viable enterprises, Ammerman says. computer systems that can link and analyze ly are unknown and not measured. Vizuete’s The research will be conducted in North data collected in electronic hospital and team, which includes scientists from the Carolina but will have national and interna- ambulance records. The idea is to get a clear- UNC School of Medicine, will look for easier, tional relevance. er picture of what diseases are most prevalent more effective ways of finding and measuring For more information on the Gillings in this setting and how they are being treated. toxic pollutants breathed by people in cities. Innovation Labs, see www.sph.unc.edu/ More complete information could result in a The team will develop and construct portable accelerate. I better understanding of the causes of disease smog instruments to test air at various loca- — BY TORREY WASSERMAN AND and more effective efforts at prevention tions around the world, and use human lung RAMONA DUBOSE

30 | VOL.1 • NO. 5 FALL 2008 NORTH CAROLINA MENTAL HEALTH SYSTEM IMPROVEMENT

North Carolina
Mental Health System Improvement aring for people with serious mental illness, C substance abuse and/or developmental disabilities has become one of North Carolina’s greatest public health challenges. One in three North Carolina adults (nearly 2 million people) have had a mental health or substance abuse disorder in the past year, and nearly 400,000













have a serious mental illness. Despite spending $2.7 billion in fiscal tem and all the factors that influence poli- Dr. Joseph Morrissey year 2006–07, problems still abound for cy outcomes,” says Morrissey, who also is a methods to improve services. In the second the North Carolina mental health system— professor of psychiatry at the UNC School year, the team will scale up to statewide including short supply of community- of Medicine and deputy director for implementation. based crisis services, over-crowded state research at the UNC Cecil G. Sheps Center Morrissey’s team includes Drs. Kristen psychiatric hospitals, growing numbers of for Health Services Research. “If policy- Hassmiller-Lich, Shoou-Yih Daniel Lee, people with mental illness who are makers cannot depict the network of rela- and Rebecca Wells, all faculty in UNC’s detained in jails across the state, and people tionships and feedback loops surrounding Gillings School of Global Public Health; with serious needs who do not receive the state psychiatric hospitals in a systematic Dr. Marvin Swartz from Duke University’s most effective services. and holistic manner, the result is likely to School of Medicine; and a number of com- Dr. Joseph Morrissey, UNC professor of be more of the same, that is, quick admin- munity partners. health policy and management, was award- istrative fixes that fail to resolve problems “This innovation lab represents an ed a Gillings Innovation Lab (GIL) to help for the longer term.” unprecedented opportunity for the School the state find a better way to approach In the first year, Morrissey and his team to assist government officials and con- mental health problems. Using a variety of will map the clinical, organizational and cerned citizens in improving mental health system modeling tools, he will assess the financial factors driving use of mental services for all North Carolinians who need financial and human impacts of alternative health services in North Carolina’s Orange, them,” Morrissey says. “Our objective is to policies for using state psychiatric hospi- Person, Chatham and Durham Counties. influence state policy by assessing and vet- tals. He will also examine ways to improve These sites offer both a predominantly ting optional approaches to managing the the accessibility, quality and effectiveness rural laboratory and an urban counterpart use of state psychiatric hospitals, commu- of community services as alternatives or to apply research methods, community and nity-based crisis services and county jails.” complements to these hospitals. health care provider participation and “Ultimately, he adds, “our goal is to “At this point, North Carolina policy- computer simulations to identify ways to increase the extent to which persons with makers trying to fix the system of care for make the system work better for everyone. mental illness, developmental disabilities people with serious mental illness, devel- By modeling mental health service use and/or addictions spend their lives func- opmental disabilities and/or addictions do in these counties, the team can see how tioning successfully in the community.” I not have all the tools needed to understand changes in structure and policies affect — BY TORREY WASSERMAN the complexities of the mental health sys- the entire system, and find innovative AND RAMONA DUBOSE

CAROLINA PUBLIC HEALTH | 31 features & news Vaccines
for Global Health Single-dose vaccine for multiple respiratory viruses could save lives of infants and children in developing countries

orldwide, more than five million children Wunder age five die each year from respira- tory infections like influenza and pneumonia. Nearly all of them live in the developing world.

Vaccines could save many of these young global health initiatives to promote new lives. But today’s vaccines cost too much to be interdisciplinary programs that address fun- given routinely in many developing coun- damental questions, like how to create and tries. It’s not only the cost of the vaccine itself, administer these new, stable vaccines.” but also the expense of getting the vaccines to Project partners include the Carolina people who need them most. On top of that, Vaccine Institute and its director, Dr. Robert most vaccines need to be refrigerated and E. Johnston; the UNC School of Medicine; handled carefully to stay active —impossible and Global Vaccines Inc.— a non-profit com- in many areas of the world. pany in Research Triangle Park, N.C., found- So why doesn’t someone come up with a ed and directed by Johnston. Dr. Ralph Baric more stable vaccine that’s easier to transport The team wants to create a vaccine that lems in new and creative ways. At a mini- and deliver? For one thing, vaccine develop- will have a shorter production cycle than cur- mum, this vision will allow us to establish an ment is expensive and risky. Sales of vaccines rent vaccines which can take up a year to cul- approach that could revolutionize rapid in developing countries are unlikely to ture, Baric says. This is critical to respond response vaccine genome design and provide recoup even the costs of manufacturing for effectively to emerging diseases. The team monumental protection against newly most companies. aims to develop a low-cost, single-dose vac- emerged pathogens of the future,” Baric says. But UNC epidemiology professor Dr. cine that is stable at room temperature and “This is a highly innovative, interdiscipli- Ralph Baric and his team believe there’s a way inhaled, rather than given with a needle. nary project that addresses a significant glob- to produce a single-dose synthetic vaccine They also plan to use synthetic genomics and al health issue,” adds Dr. Andrew F. Olshan, that is both affordable and easy to store and computer-based genome design. If they are professor and chair of epidemiology at the transport. To help Baric and his team explore successful, their work could lead to a whole School who is part of Baric’s team. “The proj- their ideas, the UNC Gillings School of new approach for designing and administer- ect incorporates a complete program to Global Public Health recently funded their ing other global health vaccines. design, build and manufacture a much need- proposal for a Gillings Innovation Lab (GIL). “Of course it’s risky and our group faces ed vaccine.” “Our goal is to build a whole new class of enormous challenges, especially in vaccine For more information on this GIL, visit vaccines accessible to the population who manufacture and delivery. However, the www.sph.unc.edu/accelerate. I needs them most,” says Baric, leader of the beauty of the Gillings Gift is that it empowers —BY TORREY WASSERMAN AND project. “We’ll partner with existing UNC scientists to tackle formidable global prob- RAMONA DUBOSE

32 | VOL.1 • NO. 5 FALL 2008 UNC BIOSTATISTICIANS

UNC BIOSTATISTICIANS MAKE THE NUMBERS ADD UP IN BIOMEDICAL RESEARCH

ince the department was established in 1949, UNC biostatisticians Shave been on the cutting edge of applying statistical analysis to health care issues. They laid the groundwork for collecting and analyzing biomedical data and revolutionizing the structure of modern clinical trials. (See page 16.) ⌽ The momentum of that early work has only increased, as new faculty members have teamed up with veterans, expanding and enhanc- ing the science. ⌽ In these subsequent pages and throughout this entire issue of Carolina Public Health, we illustrate the department’s accomplish- ments by highlighting select examples of work done by both legendary and up-and-coming faculty members. Read on to learn more! 

CAROLINA PUBLIC HEALTH | 33 features & news

DR. BERNARD G. GREENBERG: AVisionary Leader

t would be difficult to exaggerate the and directed to formulate a Ipowerful impact of DR. BERNARD process for large, multi-center GREENBERG’S vision and creativity clinical studies. The resultant upon the UNC School of Public Health “Greenberg Report,” commis- and beyond. sioned by the National Heart A New York native who served as an Institute (now the National infantry captain in World War II, Heart, Lung, and Blood Greenberg completed a doctoral program Institute), was considered in experimental statistics at N.C. State landmark. (See page 16 and University in 1949. That year, at the age of www.sph.unc.edu/cph/ 29, he was appointed chair of the newly weblinks.) formed Department of Biostatistics at Greenberg’s academic UNC-Chapel Hill. career was marked by many Greenberg’s leadership skills brought honors, including the Ameri- immediate prestige and recognition to the can Public Health Associa- department. He insisted that his faculty be tion’s Bronfman Award for focused equally on research, teaching and contributions to research and practice. He was accomplished at obtaining education (1966) and elected Dr. Bernard G. Greenberg research and training grants, and those membership in the Inter- efforts brought fresh talent to UNC. By national Statistical Institute, the American access to health care, population growth, 1965, the department had sufficient foun- Epidemiological Society and the National the environment, mental illness, substance dation to offer a doctorate in biostatistics; Academy of Sciences, Institute of abuse and injury prevention, Greenberg soon after, master’s and doctoral programs Medicine. was a visionary in the area of human rights. emphasizing mental health, environmental His University of North Carolina hon- His son, Dr. Raymond Greenberg, fol- health, genetics, demography and health ors included a Kenan Distinguished Pro- lowed in his father’s footsteps, serving as services research were offered. fessorship (1969) and receipt of the O. founding dean of the Rollins School of The national impact and global reach of Max Gardner Award for contributions to Public Health at Emory University and Greenberg’s work were profound. human welfare (1983). now president of the Medical University I He received the first of many training While devoted to his research, teaching of South Carolina. (Read more about grants from the National Institutes of and administrative obligations, Greenberg Ray Greenberg at www.sph.unc.edu/cph/ Health (NIH) which allowed him to travel was, by all accounts, a person involved in weblinks.) His other two children are also abroad to train students, postdoctoctoral the lives of his colleagues and students and UNC graduates. His son, Stanley, lives in fellows and faculty (1953). highly esteemed by them. He was a good Western Galilee, Israel, and daughter, I He published the first available article judge of character and talent, able to Frances Greenberg Klein, resides in (in The American Statistician) on the de- develop the department quickly by peo- Wilmington, Del. sign and conduct of clinical trials (1959). pling it wisely. He had a fierce sense of His wife, Ruth, who received a graduate I He testified before Congress that statis- social justice, continually exhibited in the degree in chemistry from Yale, is still a tics had been used inappropriately to agenda he set as department chair and powerful and beloved advocate for the determine the effectiveness of the polio later, in 1972, as dean of the School of UNC School of Public Health and attends vaccine—and that the vaccine actually Public Health. Whether inviting minority School events regularly. increased the incidence of polio (1962). students to have a voice in School govern- A lifelong nonsmoker, Greenberg died I He chaired a committee appointed by ment, or focusing on national and interna- of lung cancer in 1985. I NIH’s National Advisory Heart Council tional health challenges that included — BY LINDA KASTLEMAN

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hen DR. JAMES E. GRIZZLE suc- editor) and Journal of Chronic Diseases (advi- W ceeded Bernard Greenberg as chair sory board). His tenure as president of the in 1973, he was set to lead the largest biosta- Eastern North American Region of the tistics department in the world, as measured International Biometric Society makes him by the size of the faculty and number of stu- one of four UNC faculty who have attained dents taught. In the late 1960s and early ’70s, that honor. (Others include Drs. Bernard more students had received master's and doc- Greenberg, Gary Koch and Lisa LaVange.) toral degrees in the UNC department than at Now retired, Grizzle lives in Chapel Hill, any other institution. N.C. The department established the James Grizzle had earned a master’s degree in E. Grizzle Distinguished Alumnus Award in animal science from Virginia Polytechnic his honor, to recognize UNC biostatistics Institute, where he became curious about graduates with outstanding records in the genetics and animal breeding. Those interests development of new statistical methodolo- led him in 1956 to N.C. State University and gies and the application of statistical methods the doctor of philosophy program in experi- to important public health challenges. Dr. Barry Margolin mental studies. In 1957, he took a job as ⌽ the American Statistical Association’s research assistant in the Department of Snedecor Award and the National Institutes Biostatistics, then a joint endeavor of N.C. native of New York City, DR. BARRY of Health Director’s Award. State and UNC-Chapel Hill, with classes A MARGOLIN graduated summa cum In 1989, Margolin became director of the being taught on both campuses. laude from City College of New York in 1963 biostatistics facility at the UNC Lineberger His talents caught the eye of then-chair and quickly acquired graduate degrees from Comprehensive Cancer Center. He retired Greenberg, who invited Grizzle to join the Harvard University— a master’s in 1964 and from UNC-Chapel Hill in 1999 as professor UNC faculty in 1960. Grizzle’s research doctor of philosophy in 1967. and chair of the Department of Biostatistics focused on collaborative clinical studies of His stellar academic performance was and continues to live in Chapel Hill, N.C. leukemia and duodenal ulcer and on the rewarded with a position on the Yale ⌽ development of multivariate statistical meth- University faculty, where he served from ods. In 1971, he was named statistical coordi- 1967 to 1977 as assistant and associate profes- R. CLARENCE E. (ED) DAVIS, nator for a nine-year study, funded by the sor and, for two years, as director of graduate Dresearch professor of biostatistics at National Heart and Lung Institute, to exam- studies in statistics. UNC, is well known for his research and ine abnormalities of blood fats. In March From 1977 to 1987, he worked as a teaching in the areas of clinical trials and car- 1984, the results of this first major clinical mathematical statistician at the National diovascular disease epidemiology. trial were published, showing that people can Institute of Environmental Health Sciences in He has directed studies of heart disease in reduce their risk of heart disease by lowering Research Triangle Park, N.C., and was head Russia, Poland, China and Pakistan and was their cholesterol levels. (See page 22.) of the Institute’s statistical methodology sec- the primary biostatistician for the Lipid Grizzle served in an editorial capacity for tion. During this time, he also was an adjunct Research Clinics clinical trial— one of the four journals, including Journal of the professor of statistics at UNC. first trials to show that lowering blood cho- American Statistical Association (associate In 1987, Margolin joined the UNC biosta- lesterol reduces the risk of heart disease. (See tistics faculty as professor and chair. His page 22.) He teaches a clinical trials course at research specialty was the statistical design UNC and has taught similar courses in more and analysis of experiments, particularly than 15 countries. As part of a ten-year col- studies in genetic toxicology. laboration between the UNC Gillings School He is a fellow of the American Statistical of Global Public Health and the University of Association and a member of the Environ- Chile at Santiago, Davis teaches an annual mental Mutagen Society, the Gentoxicity and two-week course in Chile about public health Environmental Mutagen Society, the Institute research. (Read more at www.sph.unc.edu/ of Mathematical Statistics and the Inter- school_news/chile2008.) national Statistical Institute. Davis has been on the UNC Department Margolin served as associate editor of the of Biostatistics faculty since 1972, including Journal of the American Statistical Association his service as director of the Collaborative and the Annals of Mathematical Statistics and Studies Coordinating Center (1991–1997) as statistical editor for Environmental and as interim chair and chair of the depart- Mutagenesis. Among his many honors were ment (1997–2005). In addition to his faculty Dr. James E. Grizzle

CAROLINA PUBLIC HEALTH | 35 features & news

Kosorok has developed methods for using ⌽ surrogate and multiple outcomes to increase R. DANYU LIN, Dennis Gillings cost-effectiveness of clinical trials. His work DDistinguished Professor of Biostatis- in empirical processes and semiparametric tics at UNC, is an internationally recognized inference has led to foundational theory for leader in survival analysis and statistical improved data analysis in genetics, clinical genetics. His work has transformed the ways trials, and epidemiological studies, as well as that clinical and epidemiological data are a book on the subject, published by Springer. analyzed. Lin’s research is focused on devel- He has directed or co-directed 20 doctoral oping statistical methods for the design and students. analysis of medical and public health studies. Kosorok has chaired the Data Safety Several of his methods have been incorporat- Monitoring Committee for the intramural ed into commercial software packages program of the National Institute of Child (including SAS, S-Plus and STATA) and are Health and Human Development. He is also widely used in practice. Dr. Clarence (Ed) Davis an associate editor of the prestigious Annals responsibilities, Davis makes himself avail- of Statistics and an elected fellow of both the able for biostatistical consultation with grant American Statistical Association and the writers at the School. Since accurate sampling Institute of Mathematical Statistics. and analysis are critical to successful propos- Kosorok received his doctorate in biosta- al development, Davis offers advice about tistics from the University of Washington in study design, sample size and data analysis. 1991 and was a member of the faculty at the In 1970, Davis received his doctorate University of Wisconsin-Madison from 1992 in statistics from North Carolina State through 2006. He holds both bachelor’s and University, with a minor in public health master’s degrees in music composition, as well from the University of North Carolina. He as master’s degrees in both statistics and bio- was on the faculty of the University of Florida statistics. He recently composed a new work for three years prior to coming to UNC. for full orchestra, “A Singular Continuity,” He has published more than 100 peer- which premiered with the Chapel Hill High reviewed papers concerning both theoretical School Orchestra on Dec. 4, 2007, in Chapel and applied methods of conducting clinical Hill, N.C. His daughter, Jessica, who graduat- Dr. Danyu Lin trials and epidemiologic studies. A fellow of ed from Chapel Hill High School this spring, Lin is on Thomson ISI’s list of Highly the American Heart Association and the played violin in the orchestra. Cited Researchers in Mathematics —a distinct American Statistical Association, he also has “The piece was composed entirely during honor. Thompson ISI (founded as the Institute served on the editorial board of the Ameri- weekends and took several months to com- for Scientific Information) determines inclu- can Journal of Epidemiology. plete,” Kosorok says. sion on the list by indexing the world’s schol- ⌽ arly literature from a wide range of subjects and collecting citation references from mil- R. MICHAEL R. KOSOROK, pro- lions of articles over the past 40 years. Dfessor and chair of the UNC Lin’s research has been funded continuous- Department of Biostatistics since 2006, has ly for more than 15 years by the National published more than 80 peer-reviewed Institutes of Health (NIH). In fact, one of Lin’s papers related to clinical trials, cystic fibrosis NIH grants was converted to the prestigious epidemiology, and applications of empirical MERIT (Method to Extend Research in Time) processes and semiparametric methods in Award in 2005. MERIT Awards provide long- biostatistics. Kosorok also holds a joint term support to investigators with outstanding appointment as professor of statistics and records of scientific achievement in research operations research in UNC’s College of Arts areas of special importance or promise. and Sciences. Lin has been an author on more than 120 His research has included being senior stat- peer-reviewed publications, most in premier istician on a large randomized trial which led statistical and genetic journals. Since 1999, he to a change in national policy favoring nation- has served as an associate editor of wide newborn screening for cystic fibrosis. Biometrika. Dr. Michael R. Kosorok

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In 1999, Lin received the prestigious studies in UNC’s Department of Biostatistics Mortimer Spiegelman Gold Medal from the and program director of the department’s American Public Health Association for out- cancer genomics training grant. standing contributions to biostatistics. He Ibrahim has directed or co-directed 15 doc- was elected a fellow of the Institute of toral students and five postdoctoral fellows. Mathematical Statistics in 1999 and of the He has served on several national committees American Statistical Association in 2000. and study sections, including as current chair After earning a doctorate from the of the American Statistical Association’s sec- University of Michigan in 1989, Lin attended tion on Bayesian statistical science. He is a reg- a year-long postdoctoral training program at ular member of NIH’s biostatistical methods Harvard University before joining the faculty and research design study section. of the University of Washington’s Depart- Ibrahim received his doctorate in statistics ment of Biostatistics. There, he was promoted from the University of Minnesota in 1988. He to tenured associate professor (1994) and has published more than 160 research papers, professor (1998). He joined the UNC biosta- most in top statistical journals. He also has Dr. Jianwen Cai tistics faculty in 2001. published two advanced graduate-level books cular disease, obesity, dental research and ⌽ on Bayesian survival analysis and Monte statistical methodologies in clinical trials. She Carlo methods in Bayesian computation and has developed ways to design and analyze R. JOSEPH IBRAHIM is Alumni has served as associate editor for several sta- biomedical studies to make them more cost- DDistinguished Professor of biostatistics tistical journals. effective. Her collaborative work with Dr. at UNC’s Gillings School of Global Public June Stevens, professor and chair of the Health and director of the Biostatistics and School’s Department of Nutrition, examined Data Management Core at UNC’s Lineberger the impact of age on optimal body weight Comprehensive Cancer Center. and was published in the Jan. 1, 1998, issue of Ibrahim is principal investigator for two the New England Journal of Medicine. Cai has National Institutes of Health (NIH) grants to also developed statistical methods for analyz- develop statistical methodology related to can- ing multivariate failure time and recurrent cer and genomics research. He is biostatistical event data. These methods are important to core leader for an NIH Specialized Program of identify risk factors and interventions for dis- Research Excellence —or SPORE—grant in eases which occur repeatedly, including asth- gastrointestinal cancers. With funding from ma attacks, diarrheal episodes and recurrent NIH’s National Institute of Environmental hospitalizations related to certain medical Health Sciences, he also directs the conditions. Biostatistics and Data Management Core for a Cai has been principal investigator for program project to study the systems biology four National Institutes of Health (NIH) of melanoma. Both projects are housed at the grants, has served as a member of NIH Lineberger Comprehensive Cancer Center. Dr. Joseph Ibrahim review panels and study sessions and is a Ibrahim’s areas of research focus are Ibrahim is an elected fellow of the member of the NIH Heart Failure Network. Bayesian inference, missing data problems American Statistical Association and the Author of more than 100 peer-reviewed and genomics. Bayesian methods are gaining Institute of Mathematical Statistics and an publications in statistical and biomedical popularity in clinical trials because they pro- elected member of the International journals, Cai currently serves as associate edi- vide sound mathematical tools for analyzing Statistical Institute. tor for Biometrics and Lifetime Data Analysis. data about a problem while taking into ⌽ She is an elected member of the Eastern account information from previous studies. North American Regional Committee of the (See page 16.) R. JIANWEN CAI, professor and International Biometric Society (2007–2009), With more than 15 years’ experience Dassociate chair of the UNC an elected fellow of the American Statistical working in cancer clinical trials, Ibrahim Department of Biostatistics, joined the Association (ASA), and treasurer/secretary of directs the UNC Center for Innovative School’s faculty in 1992 after earning a doc- the ASA biometrics section (2007–2008). Clinical Trials —one of eight Gillings torate in biostatistics from the University of In addition to her research and adminis- Innovation Labs funded by a gift to the Washington. She served as interim chair of trative acumen, Cai is a respected educator. School from Dr. Dennis and Joan Gillings the department in 2006. She was the 2004 recipient of the School’s (see page 29). He is also director of graduate Cai’s research interests include cardiovas- Award for Excellence in Teaching.

CAROLINA PUBLIC HEALTH | 37 features & news

⌽ Sen’s work. Currently, Sen is editor-in-chief R. PRANAB K. SEN, a native of of Sankhya, the Indian journal of statistics. DIndia, first came to UNC in 1965 as a Sen has been recognized with numerous visiting assistant professor of biostatistics at awards throughout his career. He won the UNC-Chapel Hill. Since 1982, he has served Senior Noether Award from the American as Cary C. Boshamer Distinguished Professor Statistical Association in 2002, the Commem- of biostatistics at the School. He is also pro- oration Medal in Mathematics and Physics in fessor of statistics and operations research in 1998, and the UNC School of Public Health’s UNC’s College of Arts and Sciences. McGavran Award for Excellence in Teaching Sen has contributed significantly to in 1996, among others. methodological studies related to diabetes, Sen was Platinum Jubilee lecturer at the environmental health and bioinformatics as Indian Statistical Institute in 2007 and a 1983 well as clinical trials. His theoretical research lecturer in statistics sponsored by the includes a broad spectrum of multivariate, National Science Foundation’s Conference sequential and time-sequential nonparamet- Board of the Mathematical Sciences at the rics and asymptotic methods. His applica- University of Iowa. He is an elected fellow of Dr. Lawrence L. Kupper tion-oriented research interests cover non- the Institute of Mathematical Statistics and beginning a training grant in environmental parametrics in bioassay, multivariate and the American Statistical Association. biostatistics funded by the National Institute longitudinal data models and time-sequential Sen earned a Bachelor of Science, Master of Environmental Health Sciences (NIEHS). analysis. of Science and doctorate —all in statistics — He served as the grant’s program director from Calcutta University. In his leisure, he from 1972 through 2006. The grant currently enjoys reading and writing poetry, in English is funded through June 2011. It annually sup- as well as in his native Bengali. ports 20 predoctoral and eight postdoctoral ⌽ students — the largest number of pre- and postdoctoral trainees supported by any R. LAWRENCE L. KUPPER, NIEHS training grant. DAlumni Distinguished Professor of Kupper has won numerous teaching and biostatistics at UNC, received his PhD in sta- mentoring awards, including two university- tistics from UNC-Chapel Hill in 1970 and wide awards at UNC-Chapel Hill— the 2007 joined the faculty of UNC’s Department of UNC Mentor Award for Lifetime Achieve- Biostatistics that same year. ment in Teaching and Mentoring, and the Kupper’s research interests concern the 1996 UNC Distinguished Teaching Award for development and application of innovative Post-Baccalaureate Instruction. He also has statistical methods for design and data analy- been recognized with three UNC School of sis of public health studies, with specific Public Health awards — the 2003 John E. emphasis on environmental, occupational Larsh Jr. Award for Mentorship; the 1990 and women’s health. Kupper’s work has led to Bernard G. Greenberg Alumni Endowment Dr. Pranab K. Sen improved statistical methods for quantifying Award; and the 1985 McGavran Award for He is one of the most published authors human health risks due to exposure to harm- Excellence in Teaching. In 1986, Kupper was worldwide in the field of (bio-) statistics ful substances present in the workplace and elected a fellow of the American Statistical methodology. Sen has been an author on in the ambient environment. Association (ASA). He received the Distin- more than 600 publications in premier jour- He has been an author on more than 150 guished Achievement Medal from the ASA’s nals, co-authored 11 advanced monographs peer-reviewed publications in premier jour- Section on Statistics and the Environment in and texts in statistical science, co-edited 11 nals and has co-authored three textbooks: 1995. other volumes, and served on editorial Applied Regression Analysis and Other Kupper also was a member of the UNC boards of leading journals. He was a found- Multivariable Methods (four editions), Appointments, Promotions and Tenure ing editor of the statistics journals Sequential Epidemiologic Research: Principles and (APT) Committee from 2003 through 2007 Analysis and Statistics and Decisions. In 2008, Quantitative Methods and Quantitative and chaired the committee during the 2006- the Institute of Mathematical Statistics pub- Exposure Assessment. His applied regression 2007 academic year. The committee reports to lished a monograph titled Beyond Paramet- textbook has been adopted for use by nearly the UNC-Chapel Hill provost concerning all rics in Interdisciplinary Research: Festschrift in 100 universities nationally and internationally. tenure-related appointment and promotion Honor of Professor Pranab K. Sen to honor In 1971, Kupper was instrumental in decisions on the UNC-Chapel Hill campus. I

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DR. FRED A. WRIGHT has a doctorate in Biostatistics and HONGTU ZHU has a doctorate in statistics statistics from Medical Informat- from the Chinese University of Hong Kong. the University of ics as well as He was a postdoctoral associate at Yale Chicago. He held becoming a mem- University from 2001 to 2003 and has been faculty positions at ber of UW-M’s on the faculty at Columbia University. He the University of Comprehensive also worked as a California-San Cancer Center. research scientist Diego and Ohio He joined UNC’s at the New York State University Department of State Psychiatric before taking the Biostatistics in 2007. Fine’s areas of expertise Institute before position of associ- include time-to-event data analysis, statistical taking the position ate professor with UNC’s Department of genetics, diagnostic imaging methodology, of associate pro- Biostatistics in 2002. He also directs the and semi-parametric modeling. fessor with UNC’s Carolina Environmental Bioinformatics ⌽ Department of Center. Wright is currently researching Biostatistics. His methods to handle gene expression and DR. DONGLIN ZENG has a doctorate in research interests include statistics as appli- activity data, map disease genes in high- statistics from the University of Michigan at cable to psychiatry, psychometrics, and the density genome scans and control errors in Ann Arbor. He joined UNC’s Department applications of statistical methods in the multiple testing. of Biostatistics in analysis of magnetic resonance imaging ⌽ 2001 and was pro- (MRI) data. moted to associate DR. HAIBO ZHOU has a doctorate in professor in 2007. statistics from the University of Washington. Zeng’s research Other accomplished current faculty He worked as a statistician at the National interests include members of the UNC Biostatistics Institute of Environmental Health Sciences medical diagnos- Department are: before taking the tics, statistical position of profes- methods for med- Richard Bilsborrow sor with UNC’s ical imaging, and Shrikant Bangdiwala Department of applications of empirical processes and Diane Catellier Biostatistics in semi-parametric methods in biostatistics. Haitao Chu 1997. He is also ⌽ David Couper the director of the Rosalie Dominik Biostatistics Core DR. AMY HERRING has a doctorate in Lloyd Edwards at UNC’s Center biostatistics from Harvard University. She is Mayetri Gupta for Environmental an associate professor with UNC’s Depart- Robert Hamer Medicine, Asthma and Lung Biology. Zhou’s ment of Biostatistics. Herring has served as Michael Hudgens areas of expertise include statistical methods principal investigator on four projects fund- Anastasia Ivanova in outcome-dependent sampling, measure- ed by the National Ethan Lange ment error problems, survival analysis, Institutes of Steve Marron toxicology risk assessment and translational Health and the Jane Monaco research. Environmental Andrew Nobel ⌽ Protection Agency. John Preisser Her research in Bahjat Qaqish DR. JASON FINE has a Doctor of Science missing data, Katherine Roggenkamp degree in biostatistics from Harvard latent variables Todd Schwartz University. He worked as a statistician at the and longitudinal Richard Smith Dana Farber Cancer Institute and the analysis has been Paul Stewart University of Massachusetts Medical Center motivated by her interest in reproductive Chirayath Suchindran before taking the position of professor at the and environmental epidemiology, maternal Wei Sun University of Wisconsin-Madison’s (UW-M) and child health and nutrition. Young Tr uong Department of Statistics and Department of Fei Zou

CAROLINA PUBLIC HEALTH | 39 features & news

s o rd E ul Pa Six Dr.

n e S . K b na Pra Degrees Dr.

n BY LINDA KASTLEMAN co Ba vin Ke

example, his advisee Malay Ghosh (UNC, n the early 1990s, a trivia game called “Six 1969) taught Gauri Datta (University of Degrees of Kevin Bacon” was popular on college Florida, 1990), who taught Archan I Bhattacharya (University of Georgia, 2007). (We invite you to e-mail your family trees campuses. Based on the “small world” experiments and your six degrees of biostatistics to us at [email protected].) by social psychologist Dr. Stanley Milgram in 1967, Alas, it has taken us six paragraphs to come around to the Bacon, if you will — why the game’s premise was that any actor could be we are preoccupied with spheres of influence and begettings — and how any of this impacts correlated to Bacon within six steps, by way of upon the UNC Gillings School of Global Public Health or its Department of successive film co-stars. Biostatistics. Network theorists in this decade have elab- The American Mathematical Society Boshamer Distinguished Professor of biosta- orated upon Milgram’s work on six degrees of (AMS) developed its own version of the puz- tistics, who co-authored another with separation, noting that shared relationships zle. By entering the name of any published Zakkula Govindarajulu (of University of tend not to be linear, but rather clustered, like researcher at the AMS Web site, http://www. Kentucky), who co-authored with Istvan hubs of a wheel, with groupings of dynamic ams.org/mathscinet/collaborationDistance. Vincze (a founder of the Mathematical people in the center and others extending out- html, one can determine that person’s “collab- Institute of the Hungarian Academy), who ward from each hub. Such a mathematical orative distance” from another researcher penned something with Erdos. model might have pleased Dr. Bernard through their co-authors. By entering also The AMS also supports the Mathematics Greenberg, the first chair of UNC’s Depart- the name of Dr. Paul Erdos, the eccentric Genealogy Project (http://genealogy.math. ment of Biostatistics, who set in motion a 20th century Hungarian mathematician who ndsu.nodak.edu), a database of more than unique series of partnerships in the state and published more than 1,500 academic articles, 122,000 doctoral degree-holders in math- around the world — partnerships that made one can find one’s “Erdos number ”— the related fields, along with listings of their his tenure and faculty cutting-edge in the field number of co-authors that separates the mor- advisers and students. The result is a geneal- of biostatistics. tal academic from the master. ogy that preserves the legacy of those who Some of the interconnections may have For fun, we plugged in the name of Dr. train new generations of academicians in the been serendipitous, but they nonetheless cre- Jim Grizzle, the second chair of UNC’s mathematical sciences. ated lasting professional bonds. For instance, Department of Biostatistics, to find his Erdos Sen serves as an interesting example in as you’ll read elsewhere in this issue: number was 4. Grizzle co-authored an article this exercise, as well. His legacy as an educa- I Greenberg knew Dr. John Ashford, profes- with our own Dr. Pranab K. Sen, Cary C. tor extends to the fourth “generation.” For sor of statistics at Exeter,

40 | VOL.1 • NO. 5 FALL 2008 SIX DEGREES IN BIOSTATISTICS

rg nbe ee Gr d ar rn e B r. D Biostatistics

s rd a w Ed yd Llo in Dr. Dr. Shr la ikant Bangdiwa

I who had taught Dennis Gillings as a doc- er and avid traveler, Bangdiwala seems to be themselves in academics, practice and indus- toral student, everywhere at once—from Stockholm to try. These alumni include: I who was hired by Greenberg and became a Santiago—but his efforts also have benefitted I Faculty at Colorado State, Duke, Emory, colleague of Gary Koch, a young faculty powerfully the people of North Carolina. He George Mason, Georgia Southern, Johns member at UNC, has authored 120 peer-reviewed publications Hopkins, Kansas State, Penn State, the I who had met, in (West) Germany, a statis- on biostatistical methods, injury and violence University of Missouri, University of North tician from Hoescht AG, who needed a care- epidemiology, cardiovascular disease and Carolina, Vanderbilt University and the ful pharmaceutical analysis done, gastrointestinal disorders, all while serving as University of the Philippines; I whom Koch introduced to Gillings, director of the biostatistical core support I Industry managers and executives I who, when he started Quintiles as a result units of the Injury Prevention Research around the world, including at ACS of that West German project, hired Koch’s Center, the Center for Health Promotion and Healthcare Solutions, Amgen, GlaxoSmith- well-trained students as part of his research Disease Prevention, the Cecil G. Sheps Kline, Hoffman-La Roche, Paraxel, Pfizer, team. Center for Health Services Research, and the Quintiles Transnational, Rho, Inc., and Because he reached out to the best and Center for Functional Gastrointestinal and Schwarz Biosciences; brightest around the world and drew them to Motility Disorders. I Government agencies including the N.C. UNC, Greenberg was a harbinger of the UNC’s Dr. Lloyd Edwards’ efforts on Department of Health and Human Services School’s global influence. Today, members of behalf of North Carolina are far-reaching as and the National Institute of Environmental our biostatistics faculty are active in a dozen well. Although aging is one of his areas of Health Sciences; and countries, including Argentina, Brazil, Chile, research expertise, his delight is to speak with I Practicing biostatisticians in math class- Colombia, Ecuador, Egypt, India, Russia and young people about opportunities in the field rooms, and in hospitals and universities Sweden. Recent projects also have been set in of biostatistics. Edwards, associate professor including the University of North Carolina, China, Pakistan, Poland, and Uruguay, of biostatistics at the School, has worked with University of Washington, Vanderbilt and among other countries. Faculty members UNC’s Summer Pre-Graduate Research Duke University. serve as visiting professors, establish research Experience Program, which exposes quali- As we embrace our new name and ease collaborations and student exchanges, pro- fied minority undergraduate students to the into our 70th birthday, it is a good time vide consultation and training, and develop graduate research experience. Of six under- to take stock of our connectedness —with educational programs. graduates he has mentored, five have earned North Carolina; with people around the Yet their work, like Greenberg’s, is doctoral degrees in statistical sciences. world who, like us, seek health and safety for anchored firmly in the state that he felt the The six degrees of separation concept themselves and their children; with those School was obligated to serve. extends to our alumni as well. Over the years, whose intelligence anticipated the future and One example of a person simultaneously numerous UNC biostatistics faculty, includ- those whose passions propel us into the 21st at home in North Carolina and the world is ing Edwards and Drs. Gary Koch and Larry century. Dr. Shrikant Bangdiwala, UNC research pro- Kupper, have mentored countless biostatistics Someone familiar is no more than six fessor of biostatistics. A fluent Spanish speak- students who have gone on to distinguish degrees away. I

CAROLINA PUBLIC HEALTH | 41 features & news

SCHOOL NEWS

School to help United Arab Emirates assess environmental health risks

THE UNITED ARAB EMIRATES (U.A.E.), Environment and Water, Abu Dhabi Food one of the fastest developing nations in the Control Authority and Health Authority- world, has signed a two-year contract with Dubai. researchers from the School to lead an assess- The U.A.E. is a Middle Eastern federation ment of health risks due to environmental of seven states, situated on the Arabian Gulf, factors in the country. The contract is for bordering Saudi Arabia, Qatar and Oman. $12.1 million, about $9 million of which will The country, with a population of about 4.3 Dean Barbara K. Rimer is introduced to a falcon by her host, H.E. Majid Al Mansouri, Secretary be earmarked for the UNC Gillings School of million, has a highly industrialized economy General of the Environment Agency-Abu Dhabi. Global Public Health. and significant oil and natural gas reserves. UNC researchers are partnering with “The U.A.E. is developing at an unprece- improvements in public health, they’ve also U.A.E. University’s Department of Commu- dented pace and scale,” says principal investi- brought some concerns about risks due to nity Medicine and with the RAND Corp., a gator Dr. Jacqueline MacDonald, UNC assis- environmental hazards that come with an global public policy research institution. This tant professor of environmental sciences and industrialized economy.” group will work with the Environment engineering. “In the past 40 years, it has gone MacDonald leads a research team that will Agency-Abu Dhabi and its national partners, from a small, mostly nomadic and seafaring assess environmental health risks and use the the Health Authority-Abu Dhabi, U.A.E. economy to a major industrial nation. While results of these analyses to help United Arab Ministry of Health, U.A.E. Ministry of all the developments have brought some vast Emirates set priorities and develop policies for mitigating health risks. The work will involve collecting data, working with local stakehold- A spray of fountains ornaments the outside of the Emirates Palace Hotel in Abu Dhabi, ers to prioritize risks from environmental United Arab Emirates. exposures; and developing computer-based models to estimate impact of environmental exposures and the burden of disease caused by the most important risk factors, including both indoor and outdoor air pollution (espe- cially emissions stemming from oil and gas production), water pollution (both coastal and groundwater), and exposures to hazardous substances in the workplace. At the same time, the larger-scale epidemiologic study will be conducted to provide a nationwide assessment of possible links between the environment and the health of people living there. For more information on our work with the United Arab Emirates, visit www.sph.unc. edu/news/uae.html. I — BY RAMONA DUBOSE

42 | FALL 2008 SCHOOL NEWS

“Hero for the Planet” to keynote Sobsey accepts School’s Foard Lecture in April 2009 International Water Association award WILLIAM MCDONOUGH, AN INTERNATIONALLY renowned “green” architect and planner, will A TEAM OF RESEARCHERS LED BY DR. keynote the School’s 2009 Fred T. Foard Jr. Mark Sobsey received the International Memorial Lecture on the evening of April 1, Water Association’s 2008 Project Innovation 2009. The lecture and accompanying recep- Award for their research endeavor, “Ceramic tion will be held at the William and Ida Water Filters in Cambodia: A Sustainable Friday Center for Continuing Education in Solution for Rural Drinking Water Chapel Hill, N.C. Treatment.” The project is one of the Gillings McDonough, a global leader in ecological- Innovation Laboratories at the UNC Gillings ly, socially and economically intelligent School of Global architecture and planning, was twice cited by Public Health. TIME magazine — in October 2007 as a Sobsey, Kenan “Hero of the Environment” and in February Distinguished 1999, as a “Hero for the Planet.” University Profes- Founding principal of McDonough + sor of environmen- Partners, McDonough is one of the primary tal sciences and proponents and shapers of what he and his engineering in the partners call “The Next Industrial UNC Gillings School Revolution.” He has lectured and written William McDonough of Global Public Dr. Mark Sobsey extensively on his design philosophy and Presidential Green Chemistry Challenge Health, accepted the honor at the Associa- practice, and in 2002, co-authored Cradle to Award, and in 2004 he received the National tion’s East Asian and Pacific Awards Cradle: Remaking the Way We Make Things Design Award for exemplary achievement in Ceremony on June 26 in Singapore. with Michael Braungart. the field of environmental design. Dr. Joe Brown, a recent graduate of the In October 2007, McDonough brought his This year’s Foard lecture is co-sponsored UNC doctoral program in environmental sci- philosophy to North Carolina when he broke by the UNC Gillings School of Global Public ences and engineering and current faculty ground on a green mixed-use residential Health, the UNC Institute for the Environ- member at the University of Alabama at project in the heart of downtown Chapel Hill. ment, and Greenbridge Developments, LLC. Tuscaloosa, proposed the original water The Greenbridge development will offer 98 The event is free, but registration is requested purification project and worked with Sobsey residences, a retail area, green roofs, solar and can be completed at www.sph.unc.edu/ and others to initiate and field-test it in panels, rainwater runoff systems and a com- foard or by calling (919) 966-0198. I Cambodian homes.  munity learning center to teach sustainable living practices. McDonough, a fellow of the American Institute of Architects, is an alumni research professor at the University of Virginia’s RELIVE the EXCITEMENT Darden Graduate School of Business Administration and a consulting professor of We’re celebrating our School’s new name on Sept. 26, 2008, civil and environmental engineering at Stanford University. He is the former dean of with Chancellor Holden Thorp, UNC President Erskine the School of Architecture at the University Bowles and many other friends of the School. of Virginia. McDonough received the Presidential See photos and videos after the event at www.sph.unc.edu. Award for Sustainable Development in 1996—the nation’s highest environmental honor. In 2003, he earned the U.S. EPA’s

CAROLINA PUBLIC HEALTH | 43 features & news

After successful testing, Sobsey, Brown and others established the Carolina Global The Nutrition Research Institute’s new research center houses state-of-the-art equipment that will allow School scientists to Water Partnership, a research collaboration study how nutrition can enhance human health. between UNC’s Gillings School of Global Public Health and its Kenan-Flagler Business School, which is exploring ways to commer- cialize household water treatment technolo- gies in developing countries. For more information, visit www.sph.unc. edu/news/sobsey.html. I

Water filter project wins Kenan- Flagler Carolina Challenge

“CAROLINA LIQUID ASSETS,” PART OF Carolina Global Water Partnership, run by a team of students from both the public health and business schools, took first prize in the 2008 Carolina Challenge entrepreneurial business-plan competition sponsored by the UNC Kenan-Flagler Business School. School’s Nutrition Research Institute The team won the $15,000 John Stedman Social Entrepreneurship Award for their To celebrate opening of new research center business plan to manufacture and distribute ceramic water purifiers in Cambodia. They THE SCHOOL’S NUTRITION RESEARCH Dr. Steven Zeisel, NRI’s director and Kenan hope eventually to scale the operation Institute (NRI) in Kannapolis, N.C., will cel- Distinguished University Professor of nutri- throughout Southeast Asia and beyond. ebrate the opening of a new 126,000-square- tion and pediatrics in the UNC Gillings Public health students and faculty took foot research center in November 2008. NRI School of Global Public Health and the UNC second prize, too. Applied Microproducts, researchers and staff moved into the new School of Medicine. Inc., won $7,500 in the competition’s com- building in August. The new center houses NRI is located on the N.C. Research mercial category. The company, developed by state-of-the-art equipment that will allow Campus in Kannapolis, about 25 miles north- Environmental Sciences and Engineering NRI scientists to study how nutrition can east of Charlotte, N.C. The campus is a pub- Professor Dr. Frederic Pfaender, in conjunc- enhance human health. lic-private partnership, spearheaded by David tion with others, makes environmentally- NRI, part of the UNC Gillings School of Murdock, owner and chairman of the board friendly wood-treatment products for indus- Global Public Health, is devoted to discover- of Dole Food Company, Inc. The new center try utility poles to replace the hazardous ing why people differ greatly in metabolism will house a metabolic kitchen, clinical facili- materials currently used. and nutrient requirements. The institute ties, a cognitive assessment suite, high-tech For more information, visit www.sph.unc. uses cutting-edge genomic and metabolomic laboratories, office space and, tentatively, a edu/news/entrepreneurs.html. I biotechnology to develop innovative ap- body composition laboratory in which proaches to understanding the role of diet researchers can measure body density and fat. and activity in normal brain development, in “This institute will result in breakthroughs the prevention of cancer and in the preven- in how we use nutrition to enhance human tion and treatment of obesity and eating dis- health,” Zeisel says. “We will be able to tailor orders. Metabolomics is the systematic study recommendations on nutrition to the indi- of metabolites — small molecules generated vidual and not just give general guidelines. in the process of metabolism. We can change how nutrition is practiced, “We have much of the methodology avail- and by so doing, change people’s lives.”

Carolina Liquid Assets team members gather to able that could allow us to understand why For more information on the Nutrition celebrate their Carolina Challenge victory. people’s metabolisms are so different,” says Research Institute, visit www.nri.unc.edu. I

44 | VOL.1 • NO. 5 FALL 2008 SCHOOL NEWS

School’s Active Living by Design program awarded grant to support healthy communities initiative

ACTIVE LIVING BY DESIGN WAS TAPPED IN transportation and healthier food options, Health, was launched by the Robert Wood February 2008 by the Robert Wood Johnson and creating social norms to ensure that Johnson Foundation (RWJF) and now is Foundation to lead Healthy Kids, Healthy healthier choices become the easier choices. funded by a variety of organizations. The Communities, a new five-year, $44-million “Our short-term goal is to seed projects program has been successful in helping local program, to help underserved and vulnerable around the country that demonstrate which communities across the nation increase communities at greatest risk for childhood policy and environmental changes help com- active living and healthy eating by focusing obesity plan for and implement changes in munities become healthier. Our long-term on systems, policies and environmental policies, systems and environments that goal is to reduce the incidence of childhood change strategies. increase opportunities for active living and obesity in communities that are hardest hit,” For more information on Healthy Kids, healthy eating. Strunk says. Healthy Communities, visit www.healthykids By the end of the grant period, Healthy Active Living by Design, part of the healthycommunities.org. I Kids, Healthy Communities will work with School’s North Carolina Institute for Public — BY MARGARITA DE PANO up to 100 local communities across the coun- try, says Sarah Strunk, director of Active Living by Design, a national initiative to cre- ate community environments that support healthy children, youth and families. The program will focus on supporting multidisciplinary partnerships in their efforts to improve their communities, such as con- structing or enhancing parks, trailways and greenways, changing or implementing poli- cies to create more opportunities for active PHOTO BY ALBD

Mental disorders in parents linked to autism in children

PARENTS OF CHILDREN WITH AUTISM tant professor of epidemiology and mater- atric disorders, for causes of autism, Daniels were roughly twice as likely to have been nal and child health. “Establishing an asso- says. “It may eventually help identify oppor- hospitalized for a mental disorder, such as ciation between autism and other psychi- tunities to prevent or treat the disorder.” schizophrenia, than parents of other chil- atric disorders might enable future investi- The study examined 1,237 children born dren, according to an analysis of Swedish gators to better focus on genetic and envi- between 1977 and 2003 who were diagnosed birth and hospital records by a UNC Gillings ronmental factors that might be shared with autism before age 10, and compared School of Global Public Health researcher among these disorders.” them with 30,925 control subjects matched and colleagues in the U.S. and Europe. “Our research shows that mothers and for gender, year of birth and hospital. The The study, “Parental psychiatric disor- fathers diagnosed with schizophrenia were large sample size enabled researchers to dis- ders associated with autism spectrum dis- about twice as likely to have a child diag- tinguish between psychiatric histories of orders in the offspring,” appeared in the nosed with autism,” Daniels adds. “We also mothers versus fathers in relation to autism. May 5, 2008, issue of the journal Pediatrics. saw higher rates of depression and person- The association was present regardless of “We are trying to determine whether ality disorders among mothers, but not the timing of the parent’s diagnosis relative autism is more common among families fathers.” to the child’s diagnosis. with other psychiatric disorders,” says This information will help researchers For more information, visit www.sph. study author Dr. Julie Daniels, UNC assis- look among related diseases, such as psychi- unc.edu/news/autism.html. I

CAROLINA PUBLIC HEALTH | 45 features & news

Survey finds disordered eating behaviors among three out of four American women

I 53 percent of dieters are already at a from 4,023 women who answered detailed healthy weight and are still trying to lose questions about their eating habits. Results weight. and analysis appeared in SELF’s May 2008 I 39 percent of women say concerns about issue available online at www.self.com. what they eat or weigh interfere with their Bulik and study co-author Lauren Reba- happiness. Harrelson, a third-year UNC clinical psy- I 27 percent would be “extremely upset” if chology graduate student, presented the sur- they gained just five pounds. vey results at the 2008 International I 13 percent smoke to lose weight. Conference on Eating Disorders on May 17, The online survey garnered responses 2008, in Seattle, Wash. I

School to strengthen computational toxicology and bioinformatics expertise with major U.S. EPA award

THE U.S. ENVIRONMENTAL PROTECTION well as through interdisciplinary collabo- A SHOCKING SIXTY-FIVE PERCENT OF Agency has awarded our School a $3.4 rative efforts within UNC and with other American women between the ages of 25 and million grant to help strengthen our environmental health science researchers. 45 have disordered eating behaviors, accord- research portfolio in computational toxi- “We are delighted to receive this highly ing to the results of a new survey sponsored cology and bioinformatics. competitive award,” says Dr. Ivan Rusyn, by the University of North Carolina at Chapel Computational toxicology is a branch of associate professor of environmental sci- Hill and SELF Magazine. environmental health sciences that applies ences and engineering at the School, associ- “Our survey found that these behaviors cut mathematical and computer models to pre- ate director of the Curriculum in across racial and ethnic lines and are not limit- dict adverse effects of drugs and environ- Toxicology at the UNC School of Medicine, ed to any one group,” says Dr. Cynthia R. Bulik, mental chemicals and to better understand and principal investigator for the project. William and Jeanne Jordan Distinguished the ways they may cause harm to human “The UNC Gillings School of Global Public Professor of Eating Disorders in the UNC health and the environment. This relatively Health is a world leader in many areas of School of Medicine’s department of psychiatry, young discipline offers the possibility that science that improve the health of people in director of the UNC Eating Disorders Pro- scientists might be able to develop a much North Carolina and around the world, and gram, and professor of nutrition in the UNC better understanding of risks posed by the new Center will strengthen our capaci- Gillings School of Global Public Health. chemicals released into the environment. ty for understanding and predicting the Despite the stereotype that eating disor- The grant, which will be awarded over inter-individual differences in risk from ders affect mostly younger women, the sur- four years, aids the establishment of The environmental exposures.” vey found that women in their 30s and 40s Carolina Center for Computational For a list of other key UNC investiga- reported disordered eating habits at the same Toxicology (http://comptox.unc.edu). The tors in the center and more information rate as women in their 20s. Center will advance the field of computa- related to our School’s work in computa- According to the survey: tional toxicology through development of tional toxicology and bioinformatics, visit I 75 percent of women reported disordered new methods and computational tools, as www.sph.unc.edu/news/epa.html. I eating behaviors or symptoms consistent with eating disorders.

46 | VOL.1 • NO. 5 FALL 2008 SCHOOL NEWS

Grant to help North Carolina improve To date, 34 coun- ties and the state public health service quality nationwide itself have passed strict performance NORTH CAROLINA RECEIVED A $449,590 comes such as decreasing the incidence of vac- standards to be grant from the Robert Wood Johnson cine-preventable diseases or reducing the bur- accredited. Foundation (RWJF) to improve the quality of den of illness due to tobacco or alcohol use. “North Carolina public health and prepare for national public “North Carolina is a leader in this nation- has demonstrated a health accreditation. The three-year grant, al movement in public health known as commitment to im- Dr. Edward L. Baker which became effective April 15, 2008, will be accreditation,” says Dr. Edward L. Baker, proving the quality of its public health administered by the School’s service arm— NCIPH director and UNC professor of services and programs. North Carolina’s the N.C. Institute for Public Health. health policy and management, who will lead work will lead the way as other local and state The grant is part of a national program the project. “We are lucky in our state to public health agencies across the nation pre- managed by the National Network of Public have a strong partnership of the Institute, the pare for accreditation and strive to create Health Institutes (NNPHI) and the Public state Division of Public Health and the North healthier communities,” says Dr. James S. Health Leadership Society (PHLS). Carolina Association of Local Health Dir- Marks, senior vice president and director of North Carolina is one of 16 states chosen to ectors working together in what is now the health group at RWJF. participate in the program. The grant will sup- known as the North Carolina Accreditation For more information, visit www.sph.unc. port projects aimed at specific health out- Learning Collaborative.” edu/nciphnews/servicequality.html. I

UNC health researchers explore how to take interactive video games to the next level

IT’S NOT JUST CHILDREN! MANY YOUNG “Research shows that young adults play games. They will compare traditional video adults also spend hours every day playing video games as much as—or in some cases games played on home consoles with more interactive video games. Is there a way, UNC more than—children do,” Tate says. “Since active games requiring physical movement researchers wondered, to make those games young adulthood is a time of decreasing phys- beyond pushing buttons or flicking the wrist. healthier for people to play? ical activity and rapid weight gain, video These active games require that players use a Dr. Deborah Tate, assistant professor in games may provide a more active form of controller such as a dance pad, balance board the School’s Departments of Health Behavior leisure than traditional TV for this age group.” or even a guitar. and Health Education and Nutrition, will Tate and doctoral student Elizabeth Lyons, The researchers will look at effects of types lead UNC’s efforts to explore how these an avid gamer, will investigate people’s moti- of controllers that players use, the influence games could be better designed to improve vations to expend energy while playing video of players’ perspectives in the game and their players’ health. The project, supported by a feelings of presence and intrinsic motivation. grant from the Robert Wood Johnson Fifty men and 50 women, ages 18 to 35, will Foundation involves research teams at UNC participate in the study, which will examine and 11 other institutions. 10 games. “The findings may help us understand how to make traditional games more active and “Research shows that young active games more compelling,” Lyons says. adults play video games as For more information, visit www. sph.unc.edu/news/videogames.html. I much as—or in some cases more than—children do.”

CAROLINA PUBLIC HEALTH | 47 features & news

UNC SCHOOL OF P UBLIC H EALTH AWARDS & RECOGNITIONS May 2008 – September 2008 For more information on these and many other faculty, student, alumni and staff awards, honors and recognitions, visit www.sph.unc.edu/school/recognitions.

FACULTY Dr. Peggye Dilworth-Anderson, professor productivity and promotes innovation. of health policy and management at the Lesneski worked recently with the Florida Dr. Myron S. Cohen, associate vice chancel- School, has been elected president of the Department of Health to fine-tune its per- lor for global health and director of the Gerontological formance improvement process. Institute of Global Health and Infectious Society of America Diseases at UNC-Chapel Hill, received the (GSA), a position Dr. Barbara K. Rimer, dean of the School O. Max Gardner Award on May 9, 2008, she’ll assume in and Alumni Distinguished Professor of from the Board of Governors of the multi- 2009. GSA pro- health behavior and health education, co- campus University of North Carolina. motes the scientific edited the July 2008 supplement of the Cohen is the J. Herbert Bate Distin- study of aging and American Journal of Preventive Medicine guished Professor of medicine, microbiology fosters the use of (Vol. 35, Issue 1). and public health gerontological Devoted to cancer screening and the (epidemiology) and research in forming Dr. Peggye translation of cancer research into practice Dilworth-Anderson has served as direc- public policy. in the community, the issue is titled tor of the UNC Dilworth-Anderson is associate director “Increasing Screening for Breast, Cervical School of Medicine’s for aging and diversity in the UNC Institute and Colorectal Cancers.” Division of on Aging and director of the Institute’s Rimer and two other faculty members Infectious Diseases Center for Aging and Diversity (www.aging. affiliated with the School—Dr. Cathy Melvin since 1989. unc.edu). She also chairs the Appointments, and Alexis Moore —were contributors. Recognized as a Promotions and Tenure Committee at the Melvin is research associate professor of Dr. Myron S. Cohen global authority on UNC Gillings School of Global Public Health. maternal and child health and director of the transmission and prevention of Child Health Services at the UNC Cecil G. HIV/AIDS and other sexually transmitted Dr. Cheryll D. Lesneski, clinical assistant Sheps Center for Health Services Research. diseases, Cohen was honored for his inter- professor in the School’s Public Health Moore, an alumna, is project director of the national leadership in advancing HIV Leadership Program, received the 2008 Dissemination Core at UNC Lineberger research, treatment and prevention in coun- Prudential-Davis Productivity Award. The Comprehensive Cancer Center. tries around the world. awards program is a public-private initiative Abstracts of the articles are available at The Gardner award recognizes faculty chaired by Florida’s lieutenant governor and www.ajpm-online.net. Registered readers who have “made the greatest contributions sponsored by Florida Taxwatch, The Florida may access the complete text. to the welfare of the human race.” Cohen Council of 100 (a nonprofit advisory group) was selected from among faculty at all 17 and the State of Florida. Dr. Pam Silberman, research associate pro- UNC campuses. The 2008 award carries a The award recognizes state government fessor of health policy and management at $20,000 cash prize. employees whose work measurably increases the School, was recognized with the sixth

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annual Ned Brooks Award for Public Service nities and their patients. The American “go-to” person for events planning, parking by the Carolina Center for Public Service in College of Emergency Physicians is a services, and other daily facilities issues. His April 2008. Her research led to legislation 25,000-member national medical specialty efficiency, helpfulness and calm good humor concerning the state’s child health insurance society representing emergency medicine. were praised by School faculty and staff. law, dental care access, and insurance cover- The Staff Excellence Award was first pre- age for low-income populations. Silberman UNC biostatistics sented in 1991. A committee of staff mem- is president and chief executive officer of the professor Dr. bers from throughout the School vote on North Carolina Institute of Medicine. Michael Kosorok nominees, using the criteria of leadership, The Ned Brooks Award for Public has been appointed initiative and attitude. Service, named for Dr. Edward F. (Ned) to the board of Brooks, associate professor of health policy trustees of the and management at the School, recognizes National Institute faculty and staff who build sustained records of Statistical of community service through individual Sciences. Board Dr. Michael Kosorok efforts and promote involvement and guid- members serve three ance of others. years. Kosorok is chair of the Biostatistics Department at the UNC Gillings School of Megan Ellenson, 2008 graduate of the Global Public Health and holds a joint Marc Jeuland School’s master’s program in health behavior appointment as professor of statistics and finishes 15th in the Boston Marathon and health education, received the Robert E. operations research in UNC’s College of Bryan Public Service Award from the Arts and Sciences. Carolina Center for Public Service in April The National Institute of Statistical STUDENTS 2008. The award recognizes individual stu- Sciences was established in 1990 by the dents and faculty for exemplary public serv- national statistics societies and the Research School runners shine at Boston Marathon ice efforts. Triangle universities and organizations. The Several members of the School communi- While at Carolina, Ellenson worked with organization seeks to confront complex sci- ty — including one fast-moving graduate the Burmese immigrant community in entific problems of national importance and student—modeled healthy behaviors recent- Chapel Hill and Carrboro, N.C., to identify to identify and foster cross-disciplinary, ly when they participated in the 26-mile issues faced by these recent refugees. She later high-impact research involving the statistical Boston Marathon on April 21, 2008. wrote a grant to support the children’s partici- sciences. Environmental sciences and engineering pation in a school-based art therapy program. doctoral candidate Marc Jeuland finished 15th overall and third among American The American STAFF men in a field of more than 22,000 in the College of Emer- event. His time of 2 hours, 20 minutes, 57 gency Physicians Brent Wishart, facilities coordinator at seconds, was only 13 minutes longer than has recognized the School, received the School’s 2008 Staff the first place runner, Robert Cheruiyot, of Dr. Judith E. Excellence Award Kenya, who completed the course in 2:07.46. Tintinalli, profes- this summer. His Other participants from the School sor and founding friends and co- included: chair in the depart- workers honored I Patricia Drummey, recent environmental ment of emergency Dr. Judith E. Tintinalli him at a reception sciences and engineering master’s graduate, medicine at the on July 18. whose time was 3:30:13; UNC School of Medicine, as a “Hero of Wishart, who I Dr. David Leith, professor of environ- Emergency Medicine.” Tintinalli is adjunct began working at mental sciences and engineering and recent professor of health policy and management the School in 2002, Greenberg Award winner, whose time was in the UNC Gillings School of Global Public has helped oversee Brent Wishart 3:51:34, 155th in his age division; and Health. many renovation and I Dr. Harsha Thirumurthy, assistant pro- The honor recognizes emergency physi- construction tasks in Rosenau Hall and fessor of health policy and management, cians who have made significant contribu- Michael Hooker Research Center during the whose time, 2:35:58, placed him 99th among tions to emergency medicine, their commu- last several years, while also serving as the men in the race.

CAROLINA PUBLIC HEALTH | 49 features & news

Kosha Rajesh Munroe-Blum, principal and vice chan- Carolina for Kibera honored with Shah, a 2008 health cellor of McGill University in Montreal and Oklahoma’s Reflections of Hope Award policy and manage- an alumna of our School, was the School’s The Oklahoma City National Memorial and ment graduate at 2008 commencement speaker. She earned Museum honored Carolina for Kibera, Inc., the School, was her doctorate in epidemiology from the as recipient of its 2008 Reflections of Hope among 125 UNC- School in 1983. Award. The award, established in 2005 as Chapel Hill stu- A specialist in psychiatric epidemiology, part of the 10th anniversary commemora- dents inducted into Munroe-Blum has held faculty positions at tion of the Oklahoma City bombing, honors Phi Beta Kappa this Kosha Rajesh Shah the University of a living person or group whose extraordi- spring. The organization is the nation’s old- Toronto and York nary work has significantly impacted a com- est and most venerated honorary society. University. She has munity, state or nation. The award also Phi Beta Kappa membership is open to led large-scale epi- exemplifies that “hope not only survives but undergraduates in UNC’s College of Arts demiological inves- also thrives in the wake of political violence.” and Sciences and professional degree tigations of the dis- It includes a $25,000 honorarium which may programs who meet stringent eligibility tribution, preven- be used for program development, requirements. tion, course and Alumni of our School are among treatment of major Carolina for Kibera’s (CFK) leaders. Kim Dr. Jennifer Espiritu, a health care and pre- psychiatric disor- Dr. Heather Chapman, a master’s degree graduate from Munroe-Blum vention student in the School’s Public Health ders. Her work in the the School’s Department of Health Behavior Leadership Program, has received the field has earned her major support from the and Health Education, serves on CFK’s board American College of Preventive Medicine’s National Institute of Mental Health, the of directors. The organization was founded (ACPM) Don Gemson Resident Award. The Canadian National Health Research and by U.S. Marine Captain Rye Barcott and award recognizes individuals with outstand- Development Program. Executive Director Salim Mohamed, from ing achievement in community service, Kenya. scholarship, Dr. Philip Palmer Green III received an hon- Established in 2001, CFK is an interna- research, teaching orary doctor of science degree at the School’s tional, nongovernmental organization based and leadership, who spring 2008 commencement ceremony. in the Kibera slum of Nairobi, Kenya. In the have strong potential Green, a Chapel Hill native, worked in United States, CFK is an affiliated program for future contribu- the School’s biostatistics department early in of the UNC Center for Global Initiatives. tions to preventive his career. Currently, he is professor of Run by Kenyans and advised by medicine. genome sciences at American and Kenyan volunteers, the Espiritu, an offi- the University of organization promotes youth leadership and cer in the U.S. Navy Washington and an ethnic and gender cooperation in Kibera Dr. Jennifer Espiritu and chief resident in investigator for the through sports, young women’s empower- the UNC Preventive Medicine Program, has Howard Hughes ment, and community development. CFK served as a visiting scholar in the Medical Institute. also works to improve basic health care, san- Department of Homeland Security. She cur- Credited with key itation and education in Kibera. Serving as a rently works on a statewide quality-of-care algorithms and soft- model for holistic, community-based urban initiative with the UNC Family Practice ware tools that made development worldwide, CFK has helped Department and the N.C. Academy of Dr. Phillip Palmer possible the system- grassroots organizations develop youth- Green III Family Physicians. atic analysis of com- based programs in six other nations and plex genomes, Green received an undergrad- dozens of communities in Kenya. uate degree from Harvard and a doctorate For more information on Carolina for ALUMNI from the University of California at Kibera, visit http://cfk.unc.edu. I Berkeley. Dr. Heather Munroe-Blum received an Nobel Prize winner Dr. James D. Watson honorary doctor of science degree at the stated that, “without his (Green’s) Phred and School’s spring 2008 commencement Prap computation tools, the assembly of the ceremony. human genome would have moved ahead much more hesitantly, if not chaotically.”

50 | VOL.1 • NO. 5 FALL 2008 HONOR ROLL OF DONORS

“YOUR GIFTS ARE INVESTMENTS, AND WE THANK YOU FOR EVERY ONE OF THEM. The return on your investment will be far more than the gratitude of public health researchers, teachers and students, though you will have that in abundance. Your return will be solid information on your gift’s impact—discoveries made, students trained, publications made possible, clinics supported, lives touched, communities improved and the public’s health transformed. You will know that your gift— your investment—has made a difference in the protection of the world’s health and America’s future.”

– DEAN BARBARA K. RIMER School of Public Health HONOR ROLL JULY 1, 2007 TO JUNE 30, 2008 of Donors

$1,000,000 to Barry Michael Popkin Donald & Jennifer Holzworth Charles T. Bradley & $50,000,000 Pauline Reeser * Mabel Smith Johansson Ruth Ann Shults Paula B. & Gregory W. Stafford Esther Maria John Ching Kuang Chen Dennis & Joan Gillings Derek & Louise Winstanly Timothy David Neil King & Stacy-Ann Christian Kimberly Wheaton Howard J. Dunn $100,000 to $10,000 to $24,999 Donald & Marie Lauria James Kenneth Edzwald John & Catherine McConnell Harold F. Elkin $999,999 Fred & Laura Brown Stephen Allen Morse A. Donald & Dorothy Dunn* Sandra Winn Green Susanne Moulton & MaryAnn Farthing Gary & Carolyn Koch Miriam Labbok Thomas Wong Peggy & Cambridge Glenn William A. & Barbara K. Rimer & David H. Murdock Raymond Harris Greenlaw Jr. Michele A. Sollecito Bernard Glassman Jonathan Jay Pullin Michael & Andrea Griffin Anonymous Pranab Kumar Sen Jack Eugene Wilson David & Karen Harper Marilyn Tyroler Paula Billingsley Harrison William J. Tyroler $50,000 to $99,999 $2,000 to $4,999 Joan Cornoni Huntley J. Keith Crisco James Donald Kinard Anonymous $5,000 to $9,999 Charles Wayne Kinsey H. Michael Arrighi Deniese May Chaney Peter Jonathan Kolsky $25,000 to $49,999 Jeffrey Propes Baker Leah & Joseph Devlin Peggy Leatt & George H. Pink Allison Lynn Dauer Sterling Wilson Bell Leroy & Kay Doughty Julia Prince MacMillan George & Bodil Gellman Deborah Elizabeth Bender Cynthia Johnson Girman Jeffrey & Suzanne Morrison Alan Coningsby Moore

* deceased

CAROLINA PUBLIC HEALTH | 51 OPPORTUNITIES TO INVEST

James & Anne Schenck Stephen Marshall & James Edward Nix Jo Anne & Shelley Earp David & Mary Peoples-Sheps Anna Waller Douglas Martin Owen Kenneth LeRoy Eudy Jr. Gladys Siegel Danita McAllister John Edward Paul Lyne Gamble & Philip C. Singer David & Gladys McNelis Clarence Edward Pearson Kathryn Yandell Frank & Melanie Spencer Indrani Nandi David D. Potenziani Joseph Chitranjan Gardiner Fred & Alice Stanback Xumin Nie & Ming Zhong Alan & Linda Rimer Daniel Lynn Goetz & Gregory Strayhorn Richard Jay Osborne James Hess Rosen Eugenia Eng Susan E. Strunk Jane Therese Osterhaus John Spotswood Russell Jay Marshall Goldring John Henry Sweitzer Rachel Theresa Palmieri Patricia D. Saddier Hilton Thomas Goulson Boyd & Janie Switzer Wayne Pein & Susan Ennett Jacqueline van der Horst Richard Robert Hammel Mary S. Thompson Robert Francis Peoples Sergent C. David & Lucy Hardison Russell Barner Toal David Edward Pinsky Sallie Shuping-Russell Charles & Edna Hensey John Chester Triplett Carl F. Raetzsch Ilene C. Siegler & Gerald C. Hook Billy G. Turner Mark & Karen Rodin Charles Edelman Deborah Parham Hopson Dianne Stanton Ward Hugo Rogers Jiannan Song & Xiaonan Zhu Thierry Horner & Deborah Anne Wheeler Brian & Linda Sanders Alan Spalt & Susan Willey Rachel Williams Paul Martin Wiles Patsy Burgiss Sanders Sarah Lynn Strunk Louise Foushee Horney John Sterling Young Jr. Michael Gerard Schell Lydia Lansangan Tiosejo Barbara & Jaroslav Hulka Victor & Marion Schoenbach Barbara Tyroler Peter Bert Imrey $500 to $999 June Stevens & Chansuda Wongsrichanalai Mary Ellen James C. Michael Sheppa Anonymous Kuan Mu Yao Berton Harris Kaplan Robert E. Silverman William Cudd Blackwelder Steven & Susan Zeisel Rebecca King & Ellison & Electa Smith John Briscoe Roy Robert Piscitello Paul Edward Stang S. Scott Brown Maylon Earl Little Jo Anna Stephens $1,000 to $1,999 David Wayne Campbell Douglas Seward Lloyd Rachel Humphries Stevens Oscar Hunter Adams* Linda M. Cecarelli Walter R. Lynn Jeanine Hamlin Stice Michael D. Aitken & Barbara Taiyee Chang Merrill & Cynthia Mason David Strogatz & Betsy Rudolph Amy Duckett Corcell Alex Simon Mayer Rosalind Thomas John & Betsey Anderson Kenny Crump Keith & Patricia Meador M. Jackson & Jane Stutts Delton Atkinson Francis A. DiGiano Felicia E. Mebane David & Jeanie Taylor Edward L. Baker Rachael Lynn DiSantostefano Edward F. Meehan Richard & Vanessa Thorsten Frank & Harriett Barr Brenda Kay Edwards Bill & Susan Milner Fredrick Seymour Whaley S. Mae Beale George & Mary Elmore Mona Marie Moon Gary John White Margaret E. Bentley Mary Beth Fasano Hugh Holt Morrison James & Bonnie Yankaskas Gary Sterling Berger Tom & Jenifer Faulkner Sarah Taylor Morrow William & Janet Zelman Mark Dean Beuhler Edwin B. Fisher Jr. Kenneth A. Mundt Michael N. Boyd Donald & Barbara Fox Dara Lee Murphy Kerrie Eileen Boyle Stuart & Karen Gansky $250 to $499 Jeanenne Little Nelson Edward Carroll Bryant Richard & Lynda Goldberg Anonymous Raymond Joseph Nierstedt Pierre & Ma Buekens Robert Lee Hines Omid & Julie Ahdieh Jeffrey John Oberhaus & W. Stanley & Georgia Campbell Sallie Craig Tuton Huber Cutler Wilson Andrews Brent Wishart Dennis Alfred Clements III & Heinz U. Hueper Marijke Lee Annis James Patrick O’Connell Martha Ann Keels Jonathan V. James Amy Preminger Artman Andrew F. Olshan Jean Marie Colthurst Joseph Francis Kanney Mark & Suzette Bardill Anne Townsend Overman Ralph R. Cook Michael & Marilyn Knowles Eileen Danielle Barrett Herbert B. Peterson David Erwin Cooper Michael & Pamela Kosorok Edmund Gerald Barron Brian Lee Ramaley Stephen Couch Kenneth Scott Ladrach Gordon & Mary Hynes-Berry Ruth Rothman Georgia Cruz Margaret Edith Layne Taffey Louise Bisbee R. Gary & Jeanette Rozier Carol Zies Cuatrecasas Steven & Elizabeth Levitas Lynn W. Blanchard Girard Anthony Salak Ramona & Alan DuBose Carol Miller Blum James K. Schaefer

* deceased

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Rosenau Society Gifts Membership—July 1, 2007 to June 30, 2008

THE ROSENAU SOCIETY IS NAMED IN HONOR OF MILTON J. ROSENAU, THE FIRST DEAN OF THE SCHOOL OF PUBLIC HEALTH. MEMBERSHIP IN THE ROSENAU SOCIETY IS LIMITED TO BENEFACTORS MAKING A MINIMUM UNRESTRICTED CONTRIBUTION OF $1000+ TO EITHER THE SCHOOL OF PUBLIC HEALTH OR ONE OF ITS DEPARTMENTS. MEMBERSHIP MUST BE RENEWED ON AN ANNUAL BASIS.

PRESIDENTS’ CIRCLE ($5,000–$25,000) Jiannan Song and Xiaonan Zhu Douglas Seward Lloyd Deniese May Chaney Sarah Lynn Strunk Julia Prince MacMillan Keith Crisco Lydia Lansangan Tiosejo Merrill and Cynthia Mason Leroy and Kay Doughty Susan Willey & Alan Spalt Keith and Patricia Meador Donald and Jennifer Holzworth Steven & Susan Zeisel Felicia E. Mebane Esther Maria John Bill and Susan Milner Timothy David Neil King and DEANS’ CIRCLE ($1,000–$1,999) Mona Marie Moon Kimberly Wheaton Oscar Hunter Adams Hugh Holt Morrison David H. Murdock Michael D. Aitken and Betsy Rudolph Sarah Taylor Morrow Jonathan Jay Pullin John and Betsey Anderson Kenneth A. Mundt Barbara K. Rimer and Bernard Glassman Delton Atkinson Dara Lee Murphy William A. and Michele A. Sollecito Edward L. Baker Jeanenne Little Nelson Paula B. and Gregory W. Stafford S. Mae Beale Jeffrey John Oberhaus and Brent Wishart Derek and Louise Winstanly Peggy Bentley James Patrick O’Connell Gary Sterling Berger Andrew F. Olshan CHANCELLORS’ CIRCLE ($2,000–$4,999) Kerrie Eileen Boyle Anne Townsend Overman H. Michael Arrighi Edward Carroll Bryant Douglas Martin Owen Sterling Wilson Bell W. Stanley and Georgia Hobbins Campbell Herbert B. Peterson Deborah Elizabeth Bender Ching Kuang Chen John Spotswood Russell Fred and Laura Brown Dennis Clements and Martha Keels Jerry Salak Harold F. Elkin Ralph R. Cook James & Anne Schenck Peggy and Cam Glenn David Erwin Cooper David and Mary Peoples-Sheps Raymond Harris Greenlaw, Jr. Stephen Couch Gladys Siegel Michael and Andrea Griffin Carol Zies Cuatrecasas Philip C. Singer David & Karen Harper Ramona and Alan DuBose Frank & Melanie Spencer Paula Billingsley Harrison Shelley and Jo Anne Earp Fred and Alice Stanback James Donald Kinard Kenneth LeRoy Eudy, Jr. Gregory Strayhorn Charles Wayne Kinsey Lyne Gamble and Kathryn Yandell John Henry Sweitzer Gary and Carolyn Koch Jay Marshall Goldring Boyd and Janie Switzer Peggy Leatt and George Pink Sandra Winn Green Russell Barner Toal Jeffrey and Suzanne Morrison Richard Robert Hammel John Chester Triplett John Edward Paul C. David Hardison Dianne Stanton Ward David D. Potenziani Charles and Edna Hensey Paul Martin Wiles James Hess Rosen Deborah Parham Hopson Kuan Mu Yao Patricia D. Saddier Louise Foushee Horney Jacqueline van der Horst Sergent Jaroslav & Barbara Hulka Ruth Ann Shults Peter Bert Imrey Ilene C. Siegler Miriam Labbok Through June 30, 2008

CAROLINA PUBLIC HEALTH | 53 OPPORTUNITIES TO INVEST

Meg Marie Booth Douglas Donaldson Bradham Peiffer Allen Brandt Vance Brooks Dauers honor daughter’s success Duncan Brown & Janet Elliott Gail Rose Brown by providing scholarship for other students James Paul Bulman Ted Gray Chapin n 2000, while attending an NCAA basketball David Edward Cockley Itournament in Austin, Texas, Allison Lynn Terri Ann Colangelo Dauer met a group of students from the Deborah Lee Covington University of North Carolina. She spent the next Burton & Heather Craige hour talking to them. As they discussed activities Carolyn Elinor Crump and aspirations, Allison sensed that the students were deeply intelligent and insightful and desired Mara C. Cusker Gonzalez to make a difference in the world. That very day, Norris A. Dearmon she decided she would mail a college application David Carl Deubner to Chapel Hill. Gary L. Duhon “They really made an impression on her,” says Laurie D. Elam-Evans Joanne Dauer, Allison’s mother. “She kept talking Mohamed Nabil El-Khorazaty about how the students were smart, friendly, & A. Horne down-to-earth and naturally engaging with a com- Laurel Ann Files plete stranger. She said, ‘I want to be this type of Constance Anne Finch student. I want to go to this type of university.’” Lynn Schueler Fitzgerald In 2005, Allison graduated from the UNC Pradip & School of Public Health with a bachelor’s degree in health policy and administration. This year, her Swapna Gangopadhyay Allison Lynn Dauer parents are giving something back to the school Carol Zimmerman Garrison that shaped much of Allison’s professional life, and they are doing it in her name. Through the Dauer Jerry Gray Gentry Family Foundation, Dr. Edward Dauer and his wife Joanne established the Allison Lynn Dauer J. K. Ghosh Scholarship in Public Health with a gift of $125,000 to the UNC School of Public Health that is meant Lisa Armsrees Gillespie to support the education of highly qualified students seeking degrees in public health. Henry & Barbara Ginsberg “We think it’s very important to give back to institutions that have helped make you a success in Michael Craig Griffiths life,” says Edward Dauer. “Philanthropy is something you learn from your parents, so by setting up Alyssa Marie Gsell this scholarship in her name, we are underscoring its importance. We’ve no doubt Allison will pass Kerry Brent Hafner this along to her children.” Kenneth James Hausle The Dauers say their intent is to provide a life-changing difference in students’ lives by directing Richard John Heggen them toward a field that is ever growing in importance. Robert & Edwina Higgins “I am so pleased this scholarship has come about,” Allison says. “I’m honored that it is in my Kenneth & Jeanne Hoffner name. I have a strong belief in the education that the School of Public Health provides and I like the idea of giving back to a school that has given so much to me.” William & Fancy Hogan Allison now works as a registered nurse in the macular degeneration and retinal clinic at the David Bruce Holstein Bascom Palmer Eye Institute, which was named best eye hospital in the United States by U.S. News Penelope Page Howards and World Report in 2007 and 2008. She earned a bachelor’s degree in nursing from the University Stephen Shawnan Hsich of Miami shortly after she left Chapel Hill. “She’s applying her clinical degree by caring for patients Vernon Brock Hunt and her public health degree by teaching her patients how to take care of their eyes and prevent James Joseph Jetter eye disease,” says Joanne. Baxter Lee Jones Allison’s parents are also health care professionals. Joanne Dauer is a registered nurse and a clinical Dennis Joyner & Ruth Cohen instructor at the University of Miami’s School of Nursing. Edward Dauer is a medical doctor and a Michelle Crozier Kegler research associate professor of biomedical engineering and radiology, also at the University of Miami. Julian & Barbara Keil The Dauers have made many other generous gifts to the School, including a facilities gift that Katherine Gartland Kelley* named the UNC Gillings School of Global Public Health’s address — 135 Dauer Drive. I Donna Gayle King — BY MARGARITA DE PANO John & Judy Klaas Kenneth Joseph Koury

54 | VOL.1 • NO. 5 FALL 2008 HONOR ROLL OF DONORS

Jennifer Elston Lafata Edward Harris Wagner C. Trent Blackman Jen-Tse & Shu-Chung Robert & Michele Larson Martha Wilkinson Waller Aaron Earl Blair Shih Cheng Gregory Phillip Lathan Jenny Warburg Jill Susan Block Clyde & Anita Chesney Sheri Johnson Lawrence Eric & Elizabeth Whitsel Heidemarie W. Boas Vernon & Jolene Chinchilli Clarence Matthews Lee Katherine Ward Williams Linda Boise Joan Christison-Lagay Wilbert Liou-Lang Lee Deborah Marie Winn David & Elise Bolda Sharon L. Christy Marcia Joanne Levenstein Robert & Lisa Woolson Linda Marilyn T. Bollag Dorothy Cilenti Danyu Lin Larissa Borts Kathryn Clark Donald Daniel Lisnerski $100 to $249 J. Darrell Bost Michael A. Clarke Craig Stephen Maughan Edward & Lila Bostian Jan Patricia Clement Anonymous Deborah Ann McFarland Hughlene Bostian J. Steven & Catherine Cline Daniel & Kathryn Ahlport Mark Hamilton Merrill Maryanne G. Boundy William Spencer Clinger R. F. Albani Wilbur & Virginia Milhous Rebekah Sue Bowden Ronald Harper Clitherow Keith & Karen Aldridge William Clarence Miller Kristen Eastwood Bowers Cheryl Arthur Coble Alan & Barbara Alexander Beverly Nieman Mirman James H. Bowles W. Gerald Cochran Sheri D. Allen Hal Morgenstern Michael Austin Boyd Robert Martin Coker E. Jackson Allison Jr. Ilene Moss Jo Ellen Brandmeyer Christopher & Julie Connelly Heather Kay Altman Janet Mullaney Karl Brandspigel & Basil Gust Constantelos Terry P. Anderson Mary Margaret H. Mundt Juanita Coleman Elizabeth Curtis Cook Eugene & Linda Appel Timothy Keith Myers Michelle Ruth Bressler Glinda Sue Cooper William & Ellen Archer Bruce Nielsen Judith Moore Britt Melody K. Correll Matthew & Susan Arduino James Notaro Hoke Mitchem Brittain Beth Cossart Kenneth & Patricia Argo Leonard Oppenheimer Margaret Dodd Britton William Irvine Cowden Mary Susan Ariosto-Coe Louis Joseph Orban Cynthia V. Brown Gretchen Anne Cowman Susan Houts Arnold John & Zoe Parker Arthur Emil Bruestle Carol Gordon Cox Richard Allan Aronson David Rufus Patterson Edward Bryan Mary Foster Cox Annella Jean Auer Laura Pearson Lynda Bryant-Comstock Katherine Elizabeth Crosson Charles Lunsford Ayres Janice Periquet Charles Ross Buck John Irving Crowell Patricia Michel Backus Frederic K. Pfaender Claude Francis Burnham E. Stewart Crumpler A. John Bailer & Phyllis Wendt Pierce R. Stockton & Jennifer Butler Kathy Teer Crumpler Jennifer Faris-Bailer Lewis William Pollack Victor Marcial Caceres Nancy Bosworth Crutchfield Nina J. Baird Joseph & Amy Price Shirley Elizabeth Callahan Cameron Cecily D’Alpe Sandor Alan Balogh Margo Lynn Quiriconi Margaret Katherine Campbell Rahul Prakash Dalvi Edna Marsha Barber Irving & Joan Rimer Robert Frederick Campbell Sallie Cornwell Darnell Anna Lynn Barden Charles Eric Rodes Dana & Catherine Carlton Edith Maye Davis Alex James Barker Susan Marie Sanders Mercedes Renee Carnethon Ronald Gerard Davis Tommy R. Barnhardt David Hess Sarr Joseph & Jennifer Carson Claude Victor Deal Jr. Robert & Kimberly Barrier Chuan-Feng Shih & Yi-Wen Ma Juan & Suzanne Carvajal Henry & Alisa Debnam C. W. Bartholomai Linda Simoni-Wastila Meredith Casteel Clifford Earl Decker Jr. Cynthia Bowers Bartosek William Thomas Small Jr. Reid & Jessica Castrodale Carrie Anne Delcomyn Andy Dean Basinger Fraser B. Smith Edward Lee Cavenaugh Beverly Priddy Derr Sheri Ruth Bates Jonathan Carl Smith Carl & Carolyn Cerco Linda Webster Dicker Geraldine B. Beck Maura Ellen Stokes Joe Carroll Chambers Vincent Bernard DiFranco Michael Peter Bell William Thornton Stringfellow Max & Peggy Chandler Laura Lynne Dillard Jonathan Berg & Robert Charles Sykes Hsing-Yi Chang Robert Arthur Diseker Louise Henderson J. Chi-Chung & Jane Tang Shine Chang Eleanor Lorraine Dixon-Terry Cecelia Potts Berkstresser Julie Poh Thurlow Steven Channing & Winfred & Sarah Dodson Robert & Christine Berndt Mildred P. Turner Nancy Clapp-Channing Karl Maximilian Doetsch Jay Michael Bernhardt Gladwin Olin Unrau Caroline Chantry Rosalie Cecilia Dominik Elizabeth Hardaway Deborah Lee Vacca Louisa Elaine Chapman William K. Drane Birkenbeuel James William Vernon Jianhua Chen & Shao Lin Lee Stoll Dukes

* deceased

CAROLINA PUBLIC HEALTH | 55 OPPORTUNITIES TO INVEST

Charles Dunbar David Allan Green Kevin Holden Dunn Sherri Lynn Green A Charitable Gift Annuity: Erin Mary Dusch Ruth M. Greenberg Rachel K. Edmiston Stefan Grimberg & The Gift that Gives Back Brian K. Ellerby Jan DeWaters Margaret Hilda Elliott James Robert Grube II

With relative ease, you can set up a charitable gift annuity that Kenneth Elstein & Priscilla Alden Guild will allow you to receive: Lynette Keyes-Elstein Martin Edward Gurtz Michael William Enghauser Mohammad Taghi Habibian • Income for life, Sharon Ellen Epstein Howard Palmer Haines • A charitable tax deduction, and • The satisfaction of supporting the UNC Gillings School Lori Ann Turnbull Evarts Pamela Sue Haines of Global Public Health. Paul Jay Feldblum Robert McCue Hall David Bernard Fischer Barbara Norton Hamilton Let us show you what your return will be based on your age, Kevin Michael Fitzpatrick Anne Elizabeth Hammer your financial plans, and current interest rates. Once your gift is made, the rate remains fixed. Terry Lynn Flanagan James Arthur Hancock Jr.* Lynn Fontana Leeroy & Susan Hanna SAMPLE ANNUITY INTEREST RATES* Robert Harold Forbes Jr. Kacey Alexis Hanson Your Age Annuity Rate Your Ages Annuity Rate Michele Robin Forman Frank Eanes Harrell Jr. 60 5.7% 65/63 5.6% James Summers Forrester Shirley Shell Harrington 70 6.5% 70/68 5.8% Deborah R. Fowler Robert & Peggy Harris 75 7.1% 75/73 6.2% Charles D. Fox IV Mernoy & Frankie Harrison *Rates are subject to change Margaret A. Franckhauser J. Bruce Harstad Eduardo Franco & Carolyn Cantlay Hart You may indicate your need for more information by checking Eliane Duarte-Franco Fletcher Lee Hartsell Jr. the appropriate box in the enclosed envelope —or call, write, Alexa Freese Mary Meekins Harwell or e-mail: Elizabeth A. French Gene Albert Heath Lyne S. Gamble, Jr. Sharon L. Heinrich Director of Major and Planned Gifts Alice Freund UNC Gillings School of Global Public Health Dianna Frick Jules Heisler Campus Box 7407 Sarah Kent Fry Angie Hemingway Chapel Hill, NC 27599-7407 Robert Ernest Gandley Karin Janet Hemmingsen [email protected] Telephone: 919.966.8368 Brad & Julia Gardner Evelyn Small Henson Marie Whitehurst Gardner Eddie R. Hermosisima Richard Gargagliano & Rizza Duterte Hermosisima Joan Hedgecock Maureen Ann Hess George Arthur Garland Seth & Jean Hetherington Bryon & Kristi Geer Clyde Higgs Nancy O’Pry Gentry Charles & Sarah Hileman M. Ghosh Gregg Alan Hill Meena Ghosh Judith D. Hill Peter Gilmore Ruth Linder Hines Constance Glasby Matthew & Elaine Hoffman Evelyn Joyce Glass Vijaya K. Hogan Jonathan & Amira Goldsmith Carol Rowland Hogue Susan Goldstein Nick & Krista Hollander Nick Joseph Gonchoroff Jason & Laura Holt Sally Good Jack Holtzman & William A. Goolsby Pam Silberman Michael & Susan Gower William Edward Homovec G. Jay Graepel William & Beverly Hooks C. Montrose Graham Jr. Mark B. Horton Kathleen Marie Gray Joseph & Embry Howell

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Sui-Lien Hsieh Jonathan & Jennifer Huffman Melissa Lynn Hulting Scholarship bequest reflects Dunn’s Charles Humble & Victoria Freeman appreciation of opportunities UNC provided her Sara L. Huston Marshall L. Hyatt C. Christopher & Marion Idol he end of World War II was a time of movement and change for many, and Dorothy Dunn (MSPH 1946) was among those restless for new beginnings. She had earned her bachelor’s Hilary Louise Isacson T degree from the University of Illinois and had spent several years in progressively more demanding Michael Hamilton Ivey positions within the U.S. Department of Agriculture. Yet a tip from a former sociology professor T. Henry Jablonski Jr. about the dynamic environment at UNC led her to apply to the new master’s program in health Alexander M. Jackson education. Curtis & Ethel Jackson With the help of a stipend from the U.S. Public Health Service, Dunn enrolled as a Master of Michael Bradley Jacobs Science in Public Health student, taking epidemiology courses under Dr. Milton Rosenau, founding W. Jo e Ja c u m i n dean of the School, and receiving close mentoring from Dr. Lucy Morgan and Dr. Eunice “Pickie” Tyler, Mary Grenz Jalloh two women who would be instrumental in her decision to complete a Doctor of Philosophy at Purdue Carol Ruth James and then pursue academic appointments at Stout State University, Western Kentucky University, South Edna Esther Johnson Dakota State University, and the University of Illinois. Dunn ended her career after a long tenure with Elmer Marcus Johnson the U.S. Food and Drug Administration as an assistant regional director out of Chicago. Linda P. Johnson “I can say definitively,” Dunn commented several times during her life, “that I got more out of my energy and efforts at the UNC School of Public Health than at any other school I attended.” Mark Stevenson Johnson Upon her death on March 6, 2007, Dunn left a significant bequest that will establish a scholarship Phyllis H. Johnson fund for students in the School’s Department of Health Behavior and Health Education. Curtis Jones “This bequest really speaks to the meaning of Dorothy’s education here at the School of Public James & Kathleen Jones Health,” says Dr. Jo Anne Earp, professor of health behavior and health education. “It’s an education Thomas V. Jones that doesn’t stop with the earning of the degree. The deep ties remain. We are so pleased that we Todd Allen Jones knew of Dorothy’s plans in advance and had the opportunity to thank her and discuss what she Wanda Kaye Jones wanted her gift to achieve. It is such a tragedy when we learn that a graduate or friend cared Michele Laura Jonsson Funk enough to leave a bequest, and we never had an opportunity to say ‘Thank you’ or discuss its use.” Surendra Bhargav Joshi If you have planned for the School in your will or by other means, please let us know so that we William & Mary Joyner may thank you and welcome you to membership in The Gerrard Society, the University’s organization Charles Martin Kaltenbach for donors of planned gifts. I Norma Fox Kanarek — BY ELIZABETH FRENCH Lenni William Kangas Wilfried Joachim Jurgin Karmaus Amy Lansky Knowlton J. Tate Lanning Jr. Ann Hogan Leonard Coyt M. Karriker Keith Eric Kocher Melanie F. Mendoza Larkin Arnold & Zena Lerman Janis Gail Kaufman Helen Rosalie Kohler Barbara A. Larsen James Robert Leserman Melissa Turner Keck Bert Petty Krages II Bernard Guy LaRue Penny Masur Levy Christopher & Lara Kees Jennifer Lara Kriss Ira Laster Jr. Steven & Barcey Levy Charles Thomas Kekich N. Scott Kukshtel Jean Kantambu Latting Geraldine Spitzer Lewis Jimmy H. Keller Julia J. Kula Andrew & Catherine Lawler Candelaria Irene Leyvas Douglas G. Kelling Lawrence Kupper & Ava June Lay George Lawson Liggins William & Toni Kenerly Sandra Martin David Ernest Layland Henry N. Lin Barbara Kennerly Arnold Kuypers Carol Deadman Leatherman Pia Britt-Marie Lindstrom John Irvin Kester Richard Kwok & Samuel & Shannon Leder Stacy Melvin Linick Sandra E. Kick Melinda Manning Ji-Hyun Lee Dennis & Norma Lockney Tom Kincaid Patricia Weggel Laane Kelvin K. Lee Ellen D. Lopez Gail L. King Darwin Labarthe Soong Hyun Lee Randy Dean Louchart Hiram & Mary King Wendy Gwirtzman Lane David Stephen Legarth Margaret A. Lucking Charles Walton Kirby III Lisa F. Langhaug Philip Lehman & Gheorghe Luta Lynn Koss Knauff Mary Anne Laningham Judith Kincaid William Whiting Lyon * deceased

CAROLINA PUBLIC HEALTH | 57 OPPORTUNITIES TO INVEST

Juliana Meimei Ma Catherine Barrett Newhouser Robert Mark Queen Aisha M. Shoman J.H. Malone Jr. Beth Newman Robert Martin Quillin Steve Shore Khalil & Patricia Mancy Sharon Nicholson-Harrell Rose M. Quinto Valeria Denise Shropshire Terri Zimmerman March Willie Little Nodine Paula A. Quirin Jimmie Blake Shuler Jerold Lee Marlow Ruthie F. Norman Alan J. Rabideau Dorothy B. Silver Brian Robert Marshall Richard Recher Nugent Wilton Rankin Robert Silvers II & Edwin Cochran Marshall Julie Truax Nunez Bobby & Carolyn Redding Penelope Padgett A. Helen Martikainen Aubrey Christie Nutter Heidi Winn Reynolds William Golden Simpson Jr. Margaret Martin-Goldberg Donald & Mary Oberlin Victor Gregg Rhodes Jr. Elizabeth Hamerschlag Sims Theresa Ann Martino Sean Michael O’Brien Russell Howard Richardson Katherine Murray Sloan Katherine Pieper Mason Timothy Patrick O’Brien Brian D. F. Richmond Alan James Smith David Leon Matthews II Ray Thurmond Oglesby Thomas & Diana Ricketts Jason & Paige Smith M. Timothy & Timothy Wade Okabayashi Martha Cornwell Riddell Leonard Smock & Katherine McAdams Richard Davis Olin Thomas Andrew Ridgik Ellen Gilinsky Margaret Ellen Floyd McCann L. Dean Oliver Christopher Rimer V. L. Snoeyink Sunanda McGarvey C. Marc & Heidi O’Neal J. Thomas Rimer James Clifford Spilsbury Leslie Jane McGeorge William Kevin O’Neil Laurence Rimer Robert Spirtas Susan Lee McIntyre Joan Ann Oppenheimer Gary Alan Ritchie C. Jean Spratt Evelyn J. McKee Judith Stachura Ostendorf Kelly Elizabeth Ritrievi Vera Hughes Stallings Ross & Margaret McKinney Kevin John O’Toole Nancy Carol Rivers Morris Fearin Stamm Katherine Kennedy McLeod Bernice Green Otudeko Karen Tager Rivo Michael Stangl & Jerry McManus Karl Owen & Susan Buchanan James & Elaine Robb Rebecca Raymond Robert & Cynthia McMillan Janice Ann Paris Malcolm Clive Roberts Gary & Teresa Starr Heather Frances McNamara Edith Ann Parker Roger & Donna Robertson Gregg Martin Stave Sally Davis Medicke Kathleen Anne Parker Larry Philip Robinson Jane Patricia Staveley Anne Ruth Meibohm Margaret Mebane Parker Lois Collins Rohrer Becky Lynn Fisher Steele Michelle Marie Mello Nancy Jordan Parker Anthony Terrell Rolan Robert & Julie Steele Al & Sharon Melvin Donald E. Pathman Marjorie Sue Rosenthal David Steffen & Jill Kerr Susan Marie Merkel W. Wa r d Pat r i c k Bill Rowe & Susan Pollitt Julie Macon Stegall Percy & Sharon Merritt Edward & Nancy Pattishall Susan Russell William Steinbach & Gwen E. Metz Eleanor Marie Perfetto James Carlyle Rutledge Michelle Mayer Mary Jane Mietlowski Leah Perkinson Susan Martin Rynard Lisa Ames Stillman Aida C. Miller Nancy Marie Petersen Stephanie Ann Sabatini Anne Nelson Stokley Christopher Perry Miller Susan Grant Phelps Marjorie Rose Sable Elizabeth Jane Stoller Priscilla Randall Miller Ephraim Henry Phillippe III Lynne Scott Safrit Jo Frances Christian Stow Charles & Barbara Milone Richard Norman Phillips Billy Murray Sandlin Walter Straus Robert & Bernie Misenheimer Franco Piazza & Leah Beth Sansbury G. William Strein Carlon Virgina Jackson Mitchell Regina Rabinovich William Bishop Saunders G. Thomas & Anna Strickland David & Estelle Momrow Kathryn Evelyn Pickle Peter & Susan Saviteer Walter & Ann Stults Donald L. Moore Joel William Platts Daniel Solomon Schechter Kenneth & Mary Sugioka Robert Burns Moorhead Jr. Justin Edward Plummer Jerald Scott Schindler Mary Charles Suther Patricia Gripka Moorman Daniel Pomp Amy Fox Schmitzer David John Svendsgaard Anna Chaiko Morrill Jenny C. Poole Patricia Gail Schnitzer Mark Edward Swanson Helen Holt Morrison Cedric W. Porter Jr. Mark Schrader & James & Sandra Swenberg John Bertrand Mulligan Jr. Sarah Edwards Porter Karen Whichard James M. Symons Gary William Murphy E. Charlton Prather Don Scott Kara Anne Taff Mary Anne Murray Lester & Ellen Preston Alexander Seligman Pickens C. Talley Kimberly G. Nash Timothy Wayne Prince Rina Khemlani Shah Susannah Tasanee Tantemsapya Dennis Freeman Naugle Nancy Easter Proia Carol J. Shannon Barbara Joan Taylor Charlie & Margaret Nelson Debbie Quach Andrew J. Shapiro Charles D. Taylor Jr. Jacob Alan Neufeld Richard Douglas Quattrone Laura Ellis Sherrill Eugene Emerson Taylor

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Francis Curtis Thayer Jr. Gene Dennis Therriault Colin G. Thomas Jr. Maceo M. Thomas Morse names office in School’s Margaret B. Thomas Sandra Christenbury Thomas renovated Rosenau Hall Joseph Wood Thompson Shirley Jean Thompson s a doctoral student majoring in Theodore Tellef Thompson A environmental sciences and Mark Wallace Thorne engineering at UNC-Chapel Hill, Blossom McGarrity Tindall Stephen Morse spent most of his wak- Sujata Ravindra Tipnis ing hours holed up in a laboratory on Samuel Ridley Tipton Jr. the second floor of Rosenau Hall. He studied there. He conducted his Susan Baker Toal experiments there. He wrote his dis- John Eric Tobiason sertation there. Many of the skills that Eugene & Anne Todd he now uses to carry out his job as the Edward & Leslie Trainer second most senior person tasked to Anne R. Treanor handle bioterrorism issues at the Paul & Alison Trinkoff Centers for Disease Control and Thomasene Cates Troxler Prevention (CDC), he learned there. William True & Louise Flick “My time at the UNC School of Jerry Su Yao Tsai Public Health exposed me to various Marilyn Tseng aspects of public health, ranging from Jean Walker Tucker health administration to epidemiology Lou Flippin Turner to biostatistics,” says Morse. “That type of broad exposure is very helpful Margaret Bliss Umphres when it comes to developing research Emily Florence Untermeyer agendas for the CDC.” Gerald Upton & Morse says he acquired his public Dr. Stephen Morse Nancy Henshaw health training at no cost through David Utterback & scholarships and stipends he received throughout the five years he spent as a graduate student. To Mary McCutchen express his gratitude, he has made it a point to make regular Annual Fund gifts to the UNC School Martha Eloise Valiant of Public Health Foundation. This year, he increased his gift by pledging $25,000, payable over five Gladys Van Poole years, to improve the infrastructure of Rosenau Hall. In exchange, the School offered to name William Alvin Van Wie II Morse's old laboratory, now an office, after him. Patience Vanderbush “I didn't really expect anything in exchange for the money, but someone suggested that the room Michelle Bauman Villere be named after me,” recalls Morse. “I have a lot of fond memories associated with that laboratory, Andrew & Karen Voetsch so I said fine.” A former professor led Morse to the laboratory where he eventually devoted five years of his life. Cynthia Sue Walker Morse took up microbiology at California State University in San Jose, with the intention of continu- Ann Wall ing on to medical school and becoming a doctor. Along the way, however, he realized that he was Barbara Tepper Wallace more interested in the research aspect of clinical practice. So when his thesis adviser, Dr. Robert A. Bruce Davis Wallace Mah, accepted a teaching position at the UNC School of Public Health's Department of Ralph Gene Wallace Environmental Sciences and Engineering in 1964, Morse followed. “Looking into the area of research Hua Wang and infectious diseases and its impact on public health interested me more,” he says. Laurence Octavius Watkins Before he came to the CDC, Morse was a professor of microbiology and infectious diseases at the B. Peyton Watson Harvard School of Public Health and at Oregon Health Sciences University. In 1984, the CDC recruit- David Bruce Webster Jr. ed him to direct their sexually transmitted disease research program. In 1998, Morse became deputy George Weedon & director of the bioterrorism program, and in February 2008, he became associate editor for environ- Stephenie Winter mental microbiology at the National Center for Preparedness, Detection and Control of Infectious I Ganesa Rebecca Wegienka Diseases at the CDC, which also deals with bioterrorism issues. Jill Ruedy Welch — BY MARGARITA DE PANO Craig Steven Welence

* deceased

CAROLINA PUBLIC HEALTH | 59 OPPORTUNITIES TO INVEST

Kathryn Wellman Abena Konadu Asante Ronald Benson & William Robert Brieger H. Bradley Wells Jr. Carol S. Ashley Nellie Hansen Barry Britt Lisa Michelle Welsh-Skiffington Gwendolyn Andrews Baber Douglas Berg & Heather Rae Britt Roland Willis Wentworth Tracy Brazell Baker Marcia Herman-Giddens Laura R. Brogan Laurence & Constance Wescott Rodney Eugene Ball D. Mark & Maira Billings David Lee Brown J. Keith Weston Allyson M. Banas W. Malcolm Blalock Wendy Sims Bryant Margaret Emily Weydert Stacey Lynn Barger Stephen Bogdewic & John Bryson & Patricia Clark K. Cyrus Whaley Elizabeth Spruill Barr Elizabeth Lee Julian & Jane Bryttan Elizabeth Anne Whelan Patricia Malinda Barron George & Barbara Bond Sujata Chatterji Buck Stephen & Peggy Whicker Vickie E. Bass Michael & Maureen Boner George Davis Bussey William & Billie Whisnant Melissa Kane Batavia Danielle Leigh Boree Brian Calingaert Katherine LeGuin White Alan Sol Baumgarten Steven Bornstein Jolynne Campbell Tony L. Whitehead Suzanne Feikema Beeler Aleta Alyce Borrud Marci Kramish Campbell David & Hope Whitley William & Madeline Beery Frank & Mary Bowman Martha Ellen Campbell Johnette Padgett Whitley Frieda Behets William Foster Brannon Jr. Susan Young Cares W. Ralph Whitley II Bruce Steven Whitman Cheryl Lindsley Williams Janet Horsley Willis Richard Burton Wilson Dad taught her teamwork, Mom taught her science, John Winfield & Leigh Callahan Robert Oakley Winters now Devlin honors them with her gift Melvin Ray Witcher Jr. David Wohl & Alison Hilton s a child, North Carolina State Health Director Linda Kay Worman A Leah Devlin spent Sunday afternoons learning Wayne Edward Wormsley how to play basketball. Her father, Fred McCall, Grover Cleveland Wrenn Jr. worked as a basketball coach and college adminis- Joy Wu trator for 43 years at Campbell University, and he Carl Nobuo Yoshizawa took his wife and children to many of his games. “What it means to be part of a team and how Beverly Ann Young KEARNS PHOTO BY KATHLEEN important it is to stay healthy and physically active,” John & Lynda Young says Devlin, “I learned from my dad.” Christine Zahniser Devlin says she got her natural interest in the sci- Alfonso Zavala ences from her mother, Pearle, who was a biology Dr. Leah Devlin Dean Zehnder & Andrea Biddle professor at Campbell University. Both parents also Robert Norman Zelnio taught her the value of community service and higher education. “They were public servants in an Jun-Guo Zhao & Yu Lou institution of higher learning,” says Devlin. “So they gave me this notion that it’s important to give back, to keep an open hand, especially when it comes to educating people.” $50 to $99 Now Devlin is giving back to the UNC Gillings School of Global Public Health through the Fred and Pearle McCall Scholarship in Public Health, a $25,000 gift meant to support the education of highly Monica Stephanie Adamian qualified graduate students seeking a degree in Public Health. Devlin earned a master’s in public health Julie Adams administration from the School and a doctor of dental surgery from the UNC School of Dentistry. Robert Adamski With the public health system facing enormous challenges in terms of workforce development, Jean Elizabeth Alexander Devlin has chosen to give her gift to students who have demonstrated a strong commitment to pub- M. Taylor Alexander Jr. lic health practice. “It’s a small effort really, given the enormity of the problem,” she says, “but we Alia A. Al-Tayyib need to do everything we can to make sure that young people who want to get engaged in health Brent Andrew Altemose improvement have the skills and tools they need.” Laura Carrillo Alvarado Devlin says that the UNC School of Public Health has been the foundation of her career in public health. “I have a lot of respect for the quality of the programs and the faculty and the way they pre- Jane Anderson pare the workforce for the future,” she says. “I am very grateful for the opportunity and the training Judith Virginia Anderson they have afforded me, and as my parents have always taught me, I’m giving something back.” I Norma Powers Anderson Yolanda Banks Anderson — BY MARGARITA DE PANO

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L. Douglas Case Kimberly Avoy Duff David Nathaniel Cavallo Benjamin Duncan Jerry Cegielski & Jeanne Marshall Duncan Your gift today… Valerie Robison Ashley Caroline Aull Dunham Terrell & Janet Chalker Suzanne Elizabeth Eaton-Jones a healthier tomorrow Janella Faye Chapline J. Wilbert & Marianna Edgerton

M Brett Chapman Alan & Ellen Edmonds Bequests are a vital source of support for the UNC Gillings Andrea Lynne Cherrington Molly Margaret Eggleston School of Global Public Health. They provide funds to: Robert Chipman & Edward P. Ehlinger • Create scholarships Elizabeth Eggleston J. Maxton & Iris Elliott • Establish professorships Eloise Ann Clark Leslie Elliott • Build new facilities Lawrence Michael Clark Nancy Joy Ellish • Support research A. Bruce & Diana Clarke Laura Sutton Elsberg • Improve the public’s health Maurine G. Claver Alice Ross Ely The UNC Gillings School of Global Public Health’s future Tracy Lee Clayton Terry Coffin Ervin depends on you — our friends and alumni who remember the Jonathan & Amy Cohen Beth Ann S. Everly School in their estate plans. Your bequest will help to ensure Nancy Sederholm Cohn Sherry Leigh Farr the UNC Gillings School of Global Public Health’s continued Genevieve Lowry Cole Jose Antonio Felix-Filho excellence. In an era of shrinking federal support, bequests are Richard Francis Cole Praveen David Fernandes more important than ever. Arthur & Phyllis Collier Cynthia Hutton Ferrell Contact us today about including the UNC Gillings School of Hortensia Reyes De Colon Amy Ellen Fine Global Public Health in your estate plans. Let us know if you Lloyd Comstock & Leo Fishel III need more information by checking the appropriate box in the Judith Kramer Paul & Gayle Fitzgerald enclosed envelope — or call, write, or e-mail:

Lewis & Linda Coonley Margaret Mary Fitzsimmons Lyne S. Gamble, Jr. Emily Rose Miller Cooper Valerie Lynn Flax Director of Major and Planned Gifts Mary Paul Moore Cooper Laurie Judith Fox UNC Gillings School of Global Public Health Campus Box 7407 Janet Louise Cordell Bernard & Edna Franko Chapel Hill, NC 27599-7407 Donna E. Cornwall Megan Raspa Freed [email protected] John Landrum Cromer Anne Chenicek Freeman Telephone: 919.966.8368 Elsie Deana Cross Alexandra Steiner French David James Crow Robert E. Fry Nelida Alba Cuenca Deborah Ellen Fuldner Rosa Elena Cuenca Erika Beth Fulmer Claire Cumbie-Drake Wendy Lynn Fuscoe Stephen Thomas Daly Nancy Hall Gabianelli Arthur Hans Danielson Jack & Susanne Gakstatter Charles Eric Danielson Judith Ann Ganser Andrea Elizabeth Davis James Brian Garber Jennifer Lynn Davis Mia M. Gaudet Marcia von Thaden Davis Diana Marilyn Gaviria Richard & Boyd Davis Lynette Moolenaar George Robert Lloyd Davis Mary Beth Russin Gilboy Sonia Kropp Davis Rebecca Marie Glover Kudon Marion Elliott Deerhake Edgar Francis Golden Margaret Kneale Groening Holli Anne Hamilton Gregory Vladimir deLissovoy Shelley Diane Golden Zhishi Guo Mary Linn Hamilton Jamie Thomas Dilweg Harriet Falkowitz Goodstein Robert & Diane Gustines Ruth Evans Handley David Dodd David Jeremy Gordon Catherine Ann Gutmann Rosanne Buckley Hanratty Dorothy Hays Donnelly Mark & Teresa Gordon Grace E. Hafner Mary-Aileen Harkins-Schwarz Joanne Frances Dorgan Brian Huger Greene Jr. Philip Wills Haines Jane Coltrane Harrington Wendy Doughtery Anthony & Rebecca Greiner Anne Marie Hakenewerth Anita Marie Harris Joan Schneider Douglas Laura Anne Griffin Naomi Jean Hall Brian O. Harris

* deceased

CAROLINA PUBLIC HEALTH | 61 OPPORTUNITIES TO INVEST

Mark A. Harris Vickie T. Johnson Anthony Ray Locklear Victoria Stover Mordecai Michael & Suzette Harris William & Susan Johnson Everett Logue & Bonnie Brown Morell Elizabeth Payne Harrison A. Warren & Leigh Jones Claire Bourguet C. Dwayne Morse Katherine Eubanks Hartmann Karen Waters Jones Jeremy & Amy Long Robert Wesley Mullennix Lisa Miller Harvey Joanne Marie Jordan Sharon Corinne Long Bobbie Jo Munson Nancy Hickman Harvin John Gibbons Jordan Jr. William Lowry & David Martin Murdoch Gilbert Lee Hawes Francine Katz Jupiter Dawn Winstead Josh Murphy Ka He James Jurkovich & Dana & Erika Lumsden Eileen Stellefson Myers Thomas & Gail Heath Stephanie Molliconi Patricia Ann Lusk Mary Nelson Myers Cynthia Stewart Heatherly Nicholas Z. Kafoglis Rebecca Leigh Mabe Sree Lakshmi Nadella Kent Robert Helwig Samuel Kahn Pia Macdonald Theodore Cooke Nelson Robert Dart Hemrick Richard Kamens & Ann Marie Malarcher William Richard Nelson Elizabeth Joyce Hensleigh Bobette Eckland Lisa Frances Mallonee Joseph Rea Nichols Julia Lettner Hester Catherine Pascoe Kaminetzky Meera Tina Markanda Zachary & Alison Nimchuk Tara Lynn Hickey Sarah T. Kavanagh Cynthia Dawn Markham Patrick Joseph O’Connor Andrea Beth Hickle Dolores O’Brien Kearney Diane D. Marshall Dixon Raines Olive Jr. Avis Hernwall High Steve Keir Keith Ronald Marshall Margaret E. O’Neil Marion Highriter Martha Wood Kelly Christopher & Amy Clark O’Reilly Diane Wright Hirsch George Kerr Caroline Martens Jason Page & Maria Katharine Hitt Virginia King Kessing Lisa Jane Mason-Faison Kimberly Chapman Sandra McDaniel Hodges Roy Jung Woo Kim John Clyburn Matheson III Aishwarya Palwai Gaynelle Hogan Marcia Klebanow Denise Louise Matthews Cheri Maia Papier Michael & Stephanie Holder Russell S. Klingensmith James Richardson Mattocks Jr. Anna Willis Parrott Gwyn S. Hollenbeck Matthew & Lilin Koch Joseph & Gretchen Mauney Read & Cristy Patten Bryan Robert Hollinger Charles Konigsberg Jr. Lisa Renee Maxwell Carol Carswell Patterson Thomas Clemmer Holloway Alvin Korba Catherine Smith McCarroll William Edwin Paupe Richard H. Holmes Lawrence David Kornreich Thomas Joseph McCarthy III Beverly Joyce Klein Peckous Richard Lawrence Holmes Kevin & Denise Kreb Janet Lynn McCauley James Francis Penfold Patricia Holt John Henderson Lacey Moira Stephanie McCloskey Alan Garner Peroutka David Peter Horn John Eugene Lammers Scott Miller McCurley Lisa Lewis Perry Heather Lookabill Horne Joy Elizabeth Lane Kathleen Maree McFadden Howard August Peters Janice Ruffini Horner Timothy & Roberta Lane Jack Smith McGinnis Arlana Bobo Peterson George & Virginia Howard Sarah Bernadette Larkin Rebecca Wilson McGonigal David Rawson Phillips Cathrine Hoyo Nancy Warner Laszlo John McKernan & Melvin Thomas Pinn Jr. Patty Rosenquist Huffman Donald Lawrence & Lauralynn Taylor Carolyn Andrews Poe Chia Mun Hui Simone Cummings Richard Warren McLain Faith Lawrence Polkey Stephen & Marcie Hursting Terry Lee Leap A. Darlene Gifford McLeod Fred & Susan Poole Vi Gia Huynh Charles & Lois Lee Carolyn Damery McPherson David Lewis Pope Deborah Anne Hyland Kerry Lamont Lee Maria E. Meisch Sujatha Prabhakaran Timothy James Iafolla Donald Eric Lentzen Cindi McPherson Melanson Jefferson Boyce Prather Subin Im & Soowon Kim Rosemary Budd Lentzen Winjie Tang Miao Scott Martin Presson Deborah Dundas Ingram Brian & Amy Letourneau Linda Ann Miller William Armistead Price Kate A. Sullivan Ingram Jonathan Paul Levin Paul Matthew Miller Cynthia Johnston Probst A. Lee & Betty Ivester Robert & Berta Levin Christine Lorraine Moe Candace Prusiewicz & Bruce & Jessica Jacobs Ronald Howard Levine Mary Virginia Moggio Barry Beggs Bessie D. Johnson Peter Lichstein & Rose Wilcher Monahan Elizabeth Larsen Pullen Christopher James Johnson Elizabeth Gamble Elizabeth Claire Montague Muoi The Quach Derek Michael Johnson Susan Lieff Joel Gedney Montague Michael & Noreen Qualls Jaret Carl Johnson Hanford H. Lin Jonathan David Moore Pavel & Jennifer Rabiner Kathryn Schmidt Johnson Patricia Dale Lindsay Joyce Hawkins Moore Norman DePue Radford Jr. Thomas Lenoir Johnson Gang Liu & Rongling Li Peter Rankin Moore Judy R. Rafson

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Erika Lynn Rager Rohit Ramaswamy Maura Smith Rampolla Patricia Wilson Ray Balchem Scholarship supports David Reckhow & Catherine Wanat nutrition student’s choline research Martha Jean Reddout George & Joy Reed n Dr. Steven Zeisel's lab, Amy Johnson is studying how certain enzyme mutations can affect the George Arthur Reich Ibrain’s ability to metabolize choline — a nutrient found in milk and eggs which plays a critical role Chris Joseph Reimer in memory and brain function. Mary Louise Reynolds Johnson, a doctoral student in the UNC Gillings School of Global Public Health’s nutrition depart- Marilyn Anne Reynolds-Canty ment, is the recipient of a new scholarship established by Balchem Corp. The scholarship will allow Ann McAfee Ringland her to work with Zeisel over the next three years to study how choline is metabolized. Glenn & Anita Rives Zeisel, Kenan Distinguished University Professor of nutrition and pediatrics at UNC, is director of Marilyn Colby Rivkin the Nutrition Research Institute (NRI), a new component of the School located on the North Carolina Research Campus being built in Kannapolis, N.C. He is internationally recognized for nutrition Virgil & Susan Roberts research, especially in establishing the body’s need for choline. Craig Hall Robinson “Dr. Zeisel is the leading authority in choline research, so we wanted to know how our group Edward Christian Rogge could help advance his work,” says Paul Richardson, vice president of research and development at Katherine Jane Roggenkamp Balchem. “Our interest is to support continuing education on the benefits of choline.” Alton & Frances Ross Balchem manufactures choline chloride used by the food industry to fortify foods such as nutri- Dale & Joanne Ross tional drinks, cereals, breads, yogurts, nutrient bars, frozen foods and supplements. Richardson said John A. Ross the company believes the School’s research will provide important information about appropriate Lynne Schachner Roux uses for choline by the food industry. Scott Edward Rowden “The more that is known about choline, the more people will appreciate how important it is to John Runkle & Nancy Dole include in their diet,” Zeisel explains. “We are grateful that Balchem is supporting the work of a Eldon Jessie Russ young scientist.” Maria Citarella Russell Johnson adds that she is grateful for the Balchem fellowship and excited about doing research that could translate into practical application and potentially improve the nutritional value of every- S. Reid Russell III day foods. I Carol Wendt Sackett Jan Ellyn Salzer-Ogden Nat H. Sandler Karin Lastowski Sandlin Lawrence & Miriam Slifkin Elaine Symanski Louise Twiselton Mary Mann Sappenfield Claudia May Smith Douglas James Taylor Marian Raidl Van Nierop Sara Moir Sarasua Lucille Letzelter Smith Irma I. Taylor Richard & Patricia Vaughn Amy Frances Saunders Cindy Smith-Soloe J. Bradford Taylor Robert Irving Wakeley Daniel Ray Scharf Helen Easter Snow A. Cole Thies Susan Wall Wallin Jane Clowney Schroeder Ellen Sim Snyder Wayne Robert Thomann Ashlea Scott Waters Richard Schulz & Sandra Faye Snyder Donald Brett Thomas Nancy Burrow Watkins Marcia Coster-Schulz Joleen M. Soukup Kent & Robin Thomas Sharon Jean Wayne Marjory Bagby Schwartz Yvonne Hebert Sparling Alice Raymond Thomson Mitchell & Randie Weisberg Grace Rita Selicato Douglas & Patricia Spegman David Frierson Todd Robert R. Westerman Cornelia Boardman Service Gerald Eugene Speitel Jr. Forrest Glenn Tompkins Kay Suzanne Whetstone Robert & Pearl Seymour Laura Marie St. Martin Joseph & Jennifer Tracey Jeffrey Paul Wierse Mark Alan Sgan Michael Steven Stalker Duy Trong Tran Judith Bres Wildfire Martha B. Shackelford Courtney Vivian Stanion Stephen & Andrea Treimel Rachel Ann Wilfert Brent Jay Shelton John Haywood Stanley Katrina Foss Trivers Edward Richard Williams Lynn Roberta Shemanski Barbara Ellen Starrett Annie Wang Tu Margot Elizabeth Williams Betty Jane Shuler Leslie Thomas Stayner Mary Kay Tucker Ellen Katherine Wilson Kevin Richard Shuping Mary M. Stephens Mary Rose & Douglas Tully Marie-Elaine Winslow George William Siebert III Carol Elizabeth Stokes Kimberly Tum Suden Susan B. Winterle Leslie Staton Silkworth Miroslav Styblo Sarah Louise Turner Philip & Susan Witt * deceased

CAROLINA PUBLIC HEALTH | 63 OPPORTUNITIES TO INVEST

Gifts from Corporations and Foundations

$1,000,000 TO $50,000,000 Orica Watercare Radar Plaintiffs Colonna Chang Robert Wood Johnson Otsuka Maryland Medicinal Management Committee Family Foundation Foundation Laboratories, Inc. Reckitt Benckiser DePompa’s Comfortable Foods Sanofi-Aventis Salix Pharmaceuticals, Inc. & Catering $100,000 TO $999,999 Unilever Sigma-Tau Pharmaceuticals, Eco-Planta Inc. American Heart Association United Therapeutics Inc. Hazen and Sawyer, PC American Institute for The Kenneth S. Warren Starbucks Coffee Company Nascar SpeedPark Cancer Research Institute Telik, Inc. NC American Water Works Blue Cross and Blue Shield of Wyeth Theratechnologies Inc. Association and the Water North Carolina Foundation Theravance, Inc. Environment Association The COPD Foundation $5,000 TO $19,999 ThromboGene Inc. Nielsen Healthcare Group The Duke Endowment Adolor Corporation XenoPort, Inc. North Carolina Symphony Elizabeth Glaser Pediatric AstraZeneca Pharmaceuticals Orange Water and Sewer AIDS Foundation Cadbury Schweppes $1,000 TO $4,999 Authority GlaxoSmithKline Camp Dresser & McKee Inc. AARP Patterson Harkavy LLP Merck & Co., Inc. Campbell Soup Company Brick, Gentry, Bowers, Swartz, Peoples & Quigley Inc. W.K. Kellogg Foundation Copernicus Group IRB Stolze & Levis PC Pinehurst Geriatrics PA Danone Research Cabarrus Economic Simon Malls/Concord Mills $50,000 TO $99,999 Dole Food Company, Inc. Development Skateland USA American Chemistry Council Duke Energy Foundation Carolinas Medical Center – Sojourner Group, LLC Bryson Foundation Limited Dynogen Pharmaceuticals, Inc. NorthEast The Law Offices of Swindell Exxon Mobil Corporation Eisai Medical Research Inc. Duke Energy Corporation & Jones General Mills, Inc. Environmental Group of the Endowment for Health Total Wine & More Lance Armstrong Foundation Carolinas, Inc. Family Health International Louisiana Foundation for Forest Laboratories, Inc. First Presbyterian Church — July 1, 2007 to June 30, 2008 Excellence in Science, Genentech, Inc. of Raleigh Technology and Education The Harry Frank Guggenheim NC State Employees’ Novartis Animal Health Inc. Foundation Combined Campaign The Hershey Company Novartis Pharmaceuticals $20,000 TO $49,999 Hoffmann-La Roche Inc. Corporation ARCA Discovery, Inc. John P. McConnell Foundation RTI International Asheboro Elastics Corporation Kellogg Company Trussell Technologies, Inc. Balchem Corporation Ligand Pharmaceuticals Inc. Windstream Communications The Coca-Cola Company Mead Johnson Nutritionals The Dauer Family MedImmune, Inc. TO $999 Foundation Inc. Momentum Research American Water Works The Gellman Foundation National Dairy Council Association Inspire Pharmaceuticals Inc. National Water Research ARCADIS Jackson Medical Mall Institute Black & Veatch Foundation Nestlé S.A. Capital Health Kraft Foods Inc. NPS Pharmaceuticals Inc. Management Inc. McDonald’s Corporation Pfizer, Inc.

64 | VOL.1 • NO. 5 FALL 2008 HONOR ROLL OF DONORS

Eva Higdon Wood Louise M. Ball Kenneth & Marjorie Broun Frederick Emerson Davis Dana Lynn Woodruff Sarah C. Ball Bonnie Lowe Brown Noreen Hastings Davis Carol Ellen Woodside Violette Kasica Barasch Karen Elizabeth Brown Richard & Patricia Davis John Milton Worthington Carolyn Groce Barbe Steve & Kimberly Browning Jackson Harvey Day Bruce & Judith Wright Wendy Seamans Bardet Beth Brown-Limmer Kathy T. Dayvault Mary Haney Wright Clyde Henry Barganier Thomas Bruckel Michael Morgan Dechman Robert Stanley Wright John & Suzy Barile Phillip Heller Buchen Joseph & Kasey Decosimo William Craig Wright Debora L. Barnes-Josiah T. Neil & Lori Buckley Ruth Deer DeHolton Jingzhen Yang Susan Carter Barnwell Jennifer E. Buigut Betty Pierce Dennis Feng Ye & Jean Pan Shirley Mae Myers Barrett Joel Simpson Bulkley Patricia M. DeRosa Thomas Edward Youket Lisa Cohen Barrios Robert David Burkett Michael A. DeSpirito Samina Yunus David Barskey & Mary Baviello Suzanne Kathryn Burlone Kathryn Chivens Dickinson Guo Zhishi Elizabeth Rouse Bates Omisade Billie Burney-Scott Jody Marie Dietrich Zhi Zhong May Ahmad Baydoun Jeanne-Stuart James Burroughs Allen & Phyllis Dixon Katherine Shelden Ziegler Sherrill Crawford Beaman Ann Edwards Burruss Janice M. Dodds Mary Bradshaw Zizzi Kimberly Dawn Beck Donna H. Byrd Vera F. Dolan Adam Zolotor & Charles & Andrea Bell Marian Beard Caldwell Konstantinos Dovantzis & Karolyn Forbes John Witherspoon Bell Jr. Joanne Rita Campione Mary Lou Dovantzis Julia Wit Zupko Tammie Bell Madlen Polly Caplow Craig & Kimberly Dove Timothy Lee Bell Robert Francis Cappel Jr. Linda Yandell Dove To $49 Joyce Hoerr Benko William & Mary Cappleman Joan Walters Drake Amos Berkal Colleen M. Carpenter Edmond Daniel Duffy Jr. Anonymous Kendall Emenheiser Berry Betty Ellen Caywood Betsy Ferrell Durway Evelyn Larsen Aabel Richard Bilsborrow & Salley Kathryn Cessna John Harold Dygert Sheryl Wallin Abrahams Helen Koo Charles & Linda Chandler Kathleen Anderson Ebert Peggi Jan Gilbert Acker Stanley & Lora Bingham W. Ad r i a n C h ap p e l l Indika Damith Ekanayake Nazir & Keir Adam Alice Nash Blackwelder Diana Bah Chen Michelle E. Elisburg Barbara F. Adams Emily Trexler Blair Cassandra Maurer Childs Laurence Bruce Elliott Becky Angela Adams John David Blankfield Mary Anne Chillingworth Robert Stanfill Ellison Elizabeth Ann Hayes Adams Jennifer Milspaw Blattner Marjorie McCutchen Clark Catherine Boland Emrick Wade Calvin Adams Lisa Marie Blighton Marie Phillips Cloney-Williams Robert Lewis Enlow William Mason Adams Virginia Boardman Matthew Wayne Cogdell Emily McDonald Evens Indu Bala Ahluwalia Kimberly Whitman Bohler Susan Rita Cohen Sandra Tibbals Everett Lorraine Kathleen Alexander David Daniel Boree R. Matthew & Joanna Conley Lillian D. Farrar Catherine Dove Allport Christina Kathryn Borrelli David Conard Corkey R. Kelly Faulk & Norma J. Allred Steven C. Boss Amy Lynn Corneli Robin Elliott-Faulk Marc Robert Alston Barbara Sue Bostian Shiyoko Slate Cothren Hunter Elizabeth Faulkner Maren Elise Anderson Kathleen Smith Bowman Martha Lee Coulter Kathrine C. Fernandez Toni Gore Andrews Linda Keenan Brackett Diana Douglas Coyle John R. Fieberg Robert Eric Aronson Blair Urquhart Bradford Donna Lynne Cragle Kenneth B. Fiser David William Autry Jr. Kimberly Shuford Bradley Katherine Anne Cretin Leslie Fisher David Bruce Babcock Steven & Kristin Bradley-Bull Bobbie J. Cross Sheila Lani Flack Paul & Lee Ann Babinski Kateland Elizabeth Branch Nancy Rankin Crutchfield Robert & Octavia Flanagan Ellen DePew Bailey Kenneth Franklin Branch David Lawrence Cusic Michael Paul Flynn Donna Day Baird Jeanette Hollar Braswell Bruce Harold Dahlquist Jennifer Jean Francis Moazzum Nabeel Bajwa Danielle Furci Braxton Barbara Taylor Dalberth Shelley Avon Francis Debra Ann Baker Bobby Dean Brayboy Deborah Renee Dale John Anthony Frank John Curry Baker Jr. Toye Helena Brewer Kathleen Daly-Koziel Doren Dale Fredrickson Mark Daniel Baker James Michael Brindle William Darity & Daniel Herbert Freeman Jr. Philip Morgan Baker Louise Annette Brinton Andrea Mullen Martha Stines Freeze Miriam Parke Balding Paul H. Brodish Allie Culler Davis Shirley A. Fry

* deceased

CAROLINA PUBLIC HEALTH | 65 OPPORTUNITIES TO INVEST

Suzanne Arny Fullar Jennifer Smart Haynes Chaka G. Jordan Marsha Martin Lewis Ruth Hoyt Gage Kathleen Edwards Headen Elizabeth Jordan-Bell Susan Park Lewis Mariana Garrettson Melissa Dawn Hearsch Wen-Yi Huang Jung Melvin Dale Lightner Robert Milton Gastineau Mary-Katherine R. Heffern Adena Cohen Kaplan Frances Estes Likis Boris Georgeff Kristin Nicole Sudesh Kataria Alice Strozik Linyear Elaine Germano Schaible Hendricks Mimi S. Kaufman Karen Klein Lipman Jane Pentland Getchell Bradley David Hendrickson Sumner Kaufman Jeremy & Amanda Littleton Preeya S. Gholkar H. Carlisle Henley & Stephen R. Keener John Llewellyn Lobdell Barbara L. Ginley Martha Henderson Jada L. Keith John Kelly Lockhart Gary Kent Ginsberg George Joseph Hermann Mariah Leigh Keller Frank & Barbara Loda David William Glascoff Elizabeth Bowen Herring Robert & Johnea Kelley Denise Heath Londergan Angela Marie Gluesenkamp Sally Maxwell Hess Connie Kelley-Sidberry Frances Cowdrey Long Alice Jane Godfrey Julia Terrell Hickman Helene Marie Kent Suzanne Elizabeth Long Cathryn Ann Goedert Anthony & Nancy Hitchcock John Addison Kenyon Ann Amy Lowenfels Carol Janet Goerner Nancy Hochberg Ann Kesler-Anterasian Jaime C. Lucove Laura Maureen Goettinger H. Donald Hochstein Charlene Dickerson Kidd Edward William Lusk Aime Lyn Goldberg Alexander Ryan Hodges Hoke Pollock Kimball Melanie A. MacLennan Jeffrey Mark Goldman Stephen & Theresa Hoffman Mark William Kindem Krista Giersch Maddigan J. Barry Goldstein Edward Olin Holloway John Gridley King Kathryn Marley Magruder Jerome Edward Goodman Thelma Mary Holmes Wade Hampton King William Francis Maloney John Steven Goodnight Jerry Lynn Hood Sheila K. Kippley Ann Carol Maney Margaret C. Goodrich Claudia B. Horowitz William Lewis Klein Justice Allen Manning Kathleen C. Gotterup Sadaf Hossain Karen S. Kmetik Eleshia Cheadle Marceau Molly Anne Grabow Elizabeth Goheen House Julie K. Knaack Carolyn Venice Howard Marcus Mary Lee Donoho Grafe Robert Arthur Houseknecht J. Yvonne Rogers Knauff Lewis Margolis & Linda Frankel Christopher & Kristina Graham Marc Richard Houyoux David Krupke Knopf H. Belle Potter Marks Cynthia Green Cathy Howell Carolyn Reid Kohn Andrew Martin & Jill Reedy Debra Ann Green Jacqueline Noble Howell Charles & Sharon Kralick Brenda Ray Martin Peter Michael Griswold Richard Benjamin Howell III William Allen Kreutzberger Rose Marie Martin Catherine Aspden Grodensky Grace Han Huang Jamie Bayer Krischer Emerico Lionel Martinez Benjamin F. Gundelfinger Charmaine Marguis Huckabel Arun & Sarah Krishnaraj Elizabeth Annette McAlister Kenneth Gutterman Lory Thompson Huffman Mellayne Lackey Jill Ann McArdle John R. Guzek Gary Franklin Hughey Breana Goldman Lai Timothy Ann McBride Karen Kay Haas Joan Marshall Hunter Louis C. LaMotte Jr. Donald Edward McCall Ian Walker Hagans Jacqueline E. Higginson Huntly Robert Joseph Landry Anne Sheldon McCook Janet Shaver Hall Johnnie Lea Hylbert Richard & Kim Langholz Gene Frederick McCoy Lynne Anderson Hall Richard Ickes Charles Duane Larson Lauren Elizabeth Mccullough Charles Brady Hamilton Dora Il’yasova John & Susan Lasater Maura Ann McDonald Theodore George Hanekamp James & Rosemay Irion Desmond & Alice Lawler Janna Ruth McDougall Robert Michael Hanes Carie Katherine Irving Janice Slayman Lawlor Shirley Jackson McDowell Charles Proctor Haney Lois Simmons Isler Leslie J. Lawson Douglas Lyndal McKay Myra Mott Bomba Hanni R. Arnold Isley Jill Smith Leatherman Amanda Baker McKee Mary Penix Harding Robbin F. Itzler Annmarie Meredith Lee Walter & Yvette McMiller Jane Holman Hardwick Joseph Francis Jadlocki Jr. David Orrin Lee Lesa A. McPherson John J. Harrington Shirley Todd Jamison Lisa Yvonne Lefferts Michael McQuown Jennifer Shepherd Harris Gilbert Jui-Chung Jen John Christian LeGarde Margaret Elizabeth Meador Jana Harrison Cathy Anne Jenkins Kurt Vance Leininger Bruce & Sara Melosh Theresa Hatzell Morgan Lyn Johnson Joanna Massey Lelekacs James & Mary Merchant Shauna Noelle Hay Willie Spoon Johnson Martin Frederick Less James Chamblee Meredith James Albert Hayes Wilma Griffin Johnson Susan D. Levin Robert Scott Merolla Yumiko Ohta Hayes Carrie C. Johnston Katherine McLaurin Lewis Billy Ray Merritt

66 | VOL.1 • NO. 5 FALL 2008 HONOR ROLL OF DONORS

Edythe Green Merritt Richard Timothy Patton Jane Serena Mezoff David & Tracey Paul A World of Difference Donna Volney Michaux Christine Pederson Friends Making Christopher & Michele Miller Barbara Jane Pellin The UNC Gillings School of Global Public Health thanks our Claire Ward Mills Alexandra L. Penney many alumni, parents and friends who are enabling the School Joanne Tusov Mirdas Jessie Valentine Pergrin to make a world of difference through their gifts of professor- Margaret S. Misch Raymond Orlando Perry ships, scholarships, special purpose funds and building support. Carol Ann Molinari Edythe Mae Persing The following new funds were established between July 1, 2007 and June 30, 2008. Leslie A. Montana Donald Personette & Mario Monte Deborah DiGilio PROFESSORSHIPS Alexis Anne Moore Dustin J. Petersen Dennis & Joan Gillings Visiting Professorships Gary Stephen Moore Leonard Russell Peterson Jr. Dennis & Joan Gillings George Thomas Moore Jr. Sophia Sirokay Petrusz Jim Moore & Kimberley Cizerle Christopher Eric Pfeifer SCHOLARSHIPS & FELLOWSHIPS Teresa Anne Moore Diane Fistori Phillips Balchem Corporation Scholarship for Choline Research Beth Moracco Mary Ann Balchem Corporation Brett & Vicki Moran Cimochowski Phillips Clive Boxhill Jr. Scholarship in Health Policy Mary Berkley Mueller Jennifer Pue Pickett Stacy-Ann Christian Barbara Burkhardt Mullen Vern Pidcoe Allison Lynn Dauer Scholarship in Public Health James Thomas Murphy Cynthia A. Pipes Allison Lynn Dauer & family Robert Stewart Murphy Laura Maude Pless Dorothy Fay Dunn Scholarship in Health Behavior & Michael Ben Musachio Lynanne Plummer-Plunkett Health Education Sharon Myers Louise Adkins Poe Dorothy Fay Dunn Sneha Bakulesh Naik Paula O’Brien Poglinco Joseph & Gail Naimoli Elise Pohl Sandra B. Greene Scholarship in Health Leadership William James Neil Barbara Lillian Polhamus Sandra B. Greene Elizabeth Wysor Nelson Marcy Leigh Policastro Gary G. and Carolyn J. Koch Merit Scholarship in Public Health Mary A. Nelson Elisabetta Politi Gary G. and Carolyn J. Koch William Bernard Neser Sally Grabe Poux Fred and Pearle McCall Scholarship in Public Health Marlene Helen Nicholas Judith Ann Powell Leah M. Devlin Glenda Armstrong Nicolini Thomas John Prendergast Jr. Elizabeth Reaves Martin Moore Scholarship Oscar David Niswonger Jr. K.C. Price Alan C. Moore Delores L. Nobles Barbara Alison Prillaman Kelly L. Nordby George William Prothro Elizabeth E. Mumm Scholarship Elizabeth E. Mumm Marilyn Vukobratic Novosel John Chester Pulaski Jr. Jane Marie O’Doherty J. Kenneth Purvis Smith Anderson Biostatistics Fellowship Andrea Holly Okun Janice Putnam Smith, Anderson, Blount, Dorsett, Mitchell & Jernigan L.L.P. Byron Toyota Okutsu George Justice Race H. A. Tyroler Scholarship in Epidemiology Albert & Elizabeth Osbahr Myrnice McCormick Ravitch Family & friends Sara McMurray Osborne Kirk & Lisa Redwine Winstanly Scholarship Nancy Dasher Oswald Debra Jan Reese Derek & Louise Winstanly Donald Alfred Owens Jonathan & Sandra Reid Tracy Hughes Owens Linda Schoof Reilly SPECIAL PURPOSE FUNDS Alice Kinsman Page Lawrence Gerald Retchin Cynthia H. Cassell Doctoral Dissertation Award in Maternal Thomas & Bhavna Pahel Carmen Lee Retzlaff and Child Health Lawrence Robert Palmer Amanda Renee Reynolds Gail and Ralph Cassell Misook Park John & Donna Rezen Minority Health Conference Sponsorship Rebecca Susan Parsio Sheryl J. Rhodes George & Bodil Gellman Edward A. Pascarella Jimmie Lee Rhyne Ruth A. Shults Faculty Development Fund William Joseph Pate Diane Richie Ruth A. Shults Danica Luehm Patterson Wendy D. Riley

* deceased

CAROLINA PUBLIC HEALTH | 67 OPPORTUNITIES TO INVEST

Tamar Ringel-Kulka Stanley Allen Shulman Christine Bahia Tenekjian J. Luckey Welsh Jr. Michael Vernon Robertson Ann Margaret Shy Rhonda Mckenzie Terrell Kathryn Whetten Mark & Julie Robinson O. J. Sikes III Lois H. Terrill Rachel Anne Whetten Omar Justin Robles Donna C. Simmons Sarah Brill Thach Catherine Whedbee White James & Phyllis Anne Rochester Barbara Pawlik Simpson Jeffrey B. Thomas Melinda Faye Wiggins Eric Alan Rodgman William Henry Simpson Jennifer Hadley Tisdale Noel Hance Wiley Herbert Harold Rogers Debby Ferguson Singleton Karen M. Toll Donald B. Williams Jayne Johnson Romero Connie Marie Slavich Mary Ann Tomasiewicz James Earl Williams Mark Jamison Rosch Michael Paul Smeltzer Christopher R. Tompkins Jr. Lance & Diane Williams Nora Ellen Rosenberg Jan Winslow Smith Phyllis McCully Tousey Michael Kurt Williams Kiley Robert Ross Mary Lewis Smith Anh Nhat Tran Joseph Worth Williamson III Penny Faye Rosser Wanda Boger Smith Khiem T. Tran Mildred Carmichael Williford Catherine Palisi Rowan Lyle Byron Snider Susan Beth Trout Scott Vinsant Wilson Kathleen Patricia Ruane William James Snodgrass Joan Meister Truby Thomas Armand Wilson Nina Tiglio Ruckes Grady & Mary Snyder Thomas Tucker & David & Patty Winter Candie Caccia Rudzinski James Michael Snypes Jr. Stephanie Powelson Leonard Wolfenstein & Miriam Marie Rueger James Harold Southerland Craig David Turnbull Jan Kaplan Douglas James Rupert Stanley & Elizabeth Spangle Emily Thomason Tyler Anne Roberds Wood Karen Lee Rust Joseph & Marilyn Sparling Sheron Garris Tyndall Charles & Elizabeth Woodell Ronald & Nancy Rutta Joyce Annette Spencer Jennifer Hamblen Valdivia John David Wray Chris Niilo Salmi Lee Spencer Adrienne Nichole Valentino David C. Wu Ben Lovett Sanford Jill Hofmann Sperry Emily Johnson van Schenkhof Susan Reynolds Wyatt David Sasser & Kerry Quillin Robert Spielman Joyce Hilleboe Vana Robert Wynn II & Millie Jones Markus & Mariam Sauer John J. Spivey Paul Joseph Vander Straeten Sirin Yaemsiri Martha Key Saunders Stephanie Elaine Spottswood Encarnacion F. Vide Allen Yarinsky Frederick & Alison Saville Edward John Stanek III Randall Gregory Waite E. Peter Yarnell Jennie Perey Saxe Anna C. Stanley Hilda Lee Walker Peggy Kloster Yen Mary Hagaman Saylor Capitola Louise Stanley Nigel & Sharon Walker Florence Riffe Yerkes Patricia Brunton Scharko Doran Webster Stegura Heather Long Wallace Alex Yoon Sarah Elizabeth Schenck Cheryl Randy Stein Georgia Ann Walter Alan Nelson Young Susanne Schmal Marilyn Mackson Stein Edward & Elizabeth Walther Suzanne Unger Young Maria Ines Schmidt Seth Michael Steinberg Meredith Leigh Ward Ciara Zachary James Edmund Schwankl Margaret Mozingo Stephenson Edward Patrick Watters Judy Teresa Zerzan Todd Andrew Schwartz Carolyn Faye Stepney Kenna Stephenson Watts Christine Collins Zimmerman Pamela Jane Schwingl Constance Ritz Stern Michael & Karen Webb Bin Zou Susan Margaret Scott Rachel Parker Stevens Melissa Malkin Weber Edgar Franklin Seagle Pearson H. Stewart Martha Thompson Webster James E. Sells Betsy Van Belois Stikeleather John R. Wells * deceased Gary Selmeczi Stephen Ronald Stoddard Jean Aliyah Shaakir-Ali Jeanette Stokes Tarak Sunil Shah Nancy L. Stone EVERY GIFT IS VITALLY IMPORTANT to the UNC Gillings School George Shaler & Jill Rosenthal Ada Uhland Storm Eugene Hugh Shannon Justine Strand of Global Public Health and is deeply appreciated. We have made S. Drusanne Shaulis Brian & Belinda Sturm every effort to ensure the accuracy of our Honor Roll lists. We Joyce Q. Sheats Elizabeth Ann Sutherland regret any errors or omissions that may have occurred and ask John Lewis Sheets Mary Elizabeth Hibbs Sutton Judene Anne Shelley Susan Montgomery Swafford that you advise us of corrections needed by contacting Cutler Glenn Scott Shew Angela Wooten Swicegood Andrews at 919-966-8369 or [email protected]. The UNC Jeanne Louise Shingleton Jean Crane Sykes Gillings School of Global Public Health is extremely grateful for Starr Riddle Shive Sylvia Mullins Tart Esten Hollis Shomo Lisa Sloan Taylor your continued support. I

68 | VOL.1 • NO. 5 FALL 2008 KEITH CRISCO: Support for Leadership

ince 1986, Keith Crisco has been S president and chairman of Asheboro Elastics Corporation, one of the fastest growing privately held businesses in the U.S., with offices in seven countries and sales around the world. What brought success to the boy born on an Aquadale, N.C., dairy farm? Many point to his love of learning, a will- ingness to take calculated risks and his well-honed leadership skills. Now Crisco, a former White House Fellow and current member of the Asheboro [N.C.] City Council, is helping develop a new generation of leaders through a series of unrestricted gifts being used to expand leadership pro- grams at the School. “My interest is in developing leaders PHOTO BY TOM GILLESPIE who will leverage the state’s world-class assets — whether the UNC Gillings School of Global Public Health or the North Carolina Zoo,” says Crisco, who is an active supporter of both. “I’m not an expert in public health,” he says, “but as a local official, the School’s leadership — in the area of water, for instance — is of direct interest to me because the health of our citizens, our animals, and our economy depends upon it.” What could be more important?

An annual unrestricted gift to the School of $1,000 or more entitles a donor to membership in the Rosenau Society. Complete the enclosed gift card and be one of the reasons why we’re one of the leading schools of public health in the nation. NONPROFIT ORG. U.S. POSTAGE PAID UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL PPCO CAMPUS BOX 7400 CHAPEL HILL, NC 27599-7400