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9-2016 The eLife Sciences Annual Report 2015 eLife Sciences Publications Limited

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This Article is brought to you for free and by the Libraries at University of Nebraska-Lincoln at DigitalCommons@University of Nebraska - Lincoln. It has been accepted for inclusion in Copyright, Fair Use, Scholarly Communication, etc. by an authorized administrator of DigitalCommons@University of Nebraska - Lincoln. Letter from the Chairman Financial summary Research supported by any funding agency 2015 by the numbers may be submitted for consideration to eLife. Toby Coppel, The funders most represented to date include Research papers the Deutsche Forschungsgemeinschaft, published The centre of the stage at eLife in 2015 was occupied Co-Founder and Partner at The grants received during the year were slightly Analysis of expenditure by a new human ancestor – Homo naledi – discovered Mosaic Ventures more than the expenditure, resulting in an increase The growth of over 50% in publishing volumes European Commission, European Research by scientists in an extraordinary find in South Africa Chair, eLife Board of Directors in net assets in the year. has led to an increase of about a third in Council, Howard Hughes Medical Institute, Max 833 and published in eLife in two stunning papers in The specific contributions from the founders were: editorial and publishing systems costs, and in Planck Society, UK Council, Peer reviews September. The work was covered by media outlets HHMI £1.84m, £0.47m and payments to editors, and these costs now also US National Institutes of Health, US National submitted Besides the progress at the journal, in 2015 there has throughout the world, not just because of the scientific £1.84m. represent a larger proportion of total costs. Foundation, and the Wellcome Trust. also been a great deal of work at eLife on technology significance of the discovery but also because of the There has also been a continuing substantial (Source: eLife) 5,472 and innovation. Just announced was the release of New Senior openness with which the research and its associated Statement of activities, years ended December 31 level of investment in new systems. the open-source Continuum publication platform, the Editors materials were distributed. That these scientists chose 2014 and 2015 (in £ thousands) culmination of a year-long project which has enabled 1000 to publish such ground-breaking findings in eLife is eLife to take complete control of our journal website. Total expenditure testament both to the journal’s growing significance, 900 11 In 2015, we continued to collaborate with developers Revenue 2015 2014 New Reviewing and to the steady cultural shift towards greater Publishing costs The eLife Sciences from Substance and helped to introduce Lens Writer. 800 Editors transparency and collaboration in science, which lie at Grants 4,154 3,279 Technology and We also initiated a collaboration with Publons to 22% the heart of eLife’s mission. innovation 700 help give researchers credit for their peer-review Other income - 3 Annual Report 2015 600 97 contributions. Later this year, users will benefit from a Days from initial Total 4,154 3,282 submission to initial radical redesign of the entire website which has been 500 developed by the eLife product and design team. This decision* Our goal is to invest further in 400 work reflects an important part of the eLife strategy: 4 Expenses 2015 2014 Days from full eLife to enable more scientists to to research and develop new tools and methods in 300 submission to decision present their best work openly to support of open science, and to make our findings and Journal expenses 3,544 3,108 78% 200 after * the world.” resources available openly so that others can benefit. Management and general 312 290 100 33 Days from initial Continuing our work with early-career researchers, Our rate of publishing almost doubled during 2015, Total 3,856 3,398 papers Number of published research 0 submission to we introduced a series of webinars about funding 2012 2013 2014 2015 reaching around 90 articles per month by the end of Publishing costs acceptance* the year, and reflecting another strong year of growth opportunities and introduced a new travel grant program to support selected early-career authors with Other Wellcome Trust in submissions. The significant and fascinating science Changes in net assets 298 (116) Payment to editors Max Planck Society Howard Hughes Medical Institute 116 published in 2015 covered the effects of moonlight on travel to meetings. 14% Online systems Net assets at beginning of year 247 363 Staff and outsourcing * Median calendar days, based on decision dates in 2015 the reproductive biology of coral, the sensation of pain Article processing Our founding funders continue to believe that eLife will 33% in human infants, the use of molecular tweezers in HIV Net assets at end of year 545 247 12% Features control, and a project in drug discovery using a citizen catalyse and inspire widespread change in the ways Marketing science approach. However, there is still far too much that scientific research is communicated and utilised. important work being published behind subscription The eLife Board is therefore excited to see strong The full audited accounts for eLife Sciences Publications Limited for barriers, and our goal is to invest further in eLife to progress with our journal and with the development 2015 are available at 2015.elifesciences.org. As a US-registered tax- exempt organisation, we also publish detailed financial information of our technology platform, both of which will help to 24% 9% Image: Maloy (CC BY 2.0) enable more scientists to benefit from the efficient in our Form 990. and rigorous eLife process and present their best work drive the kind of changes that are needed in science, 8% openly to the world. to support early-career researchers and to accelerate scientific discovery. Helping scientists accelerate discovery © 2016 eLife Sciences Publications Ltd. Subject to a Creative Commons Attribution License, except where otherwise noted. Image: Murtaugh (CC BY 2.0) Letter from the Chairman Financial summary Research supported by any funding agency 2015 by the numbers may be submitted for consideration to eLife. Toby Coppel, The funders most represented to date include Research papers the Deutsche Forschungsgemeinschaft, published The centre of the stage at eLife in 2015 was occupied Co-Founder and Partner at The grants received during the year were slightly Analysis of expenditure by a new human ancestor – Homo naledi – discovered Mosaic Ventures more than the expenditure, resulting in an increase The growth of over 50% in publishing volumes European Commission, European Research by scientists in an extraordinary find in South Africa Chair, eLife Board of Directors in net assets in the year. has led to an increase of about a third in Council, Howard Hughes Medical Institute, Max 833 and published in eLife in two stunning papers in The specific contributions from the founders were: editorial and publishing systems costs, and in Planck Society, UK Medical Research Council, Peer reviews September. The work was covered by media outlets HHMI £1.84m, Max Planck Society £0.47m and payments to editors, and these costs now also US National Institutes of Health, US National submitted Besides the progress at the journal, in 2015 there has throughout the world, not just because of the scientific Wellcome Trust £1.84m. represent a larger proportion of total costs. Science Foundation, and the Wellcome Trust. also been a great deal of work at eLife on technology significance of the discovery but also because of the There has also been a continuing substantial (Source: eLife) 5,472 and innovation. Just announced was the release of New Senior openness with which the research and its associated Statement of activities, years ended December 31 level of investment in new systems. the open-source Continuum publication platform, the Editors materials were distributed. That these scientists chose 2014 and 2015 (in £ thousands) culmination of a year-long project which has enabled 1000 to publish such ground-breaking findings in eLife is eLife to take complete control of our journal website. Total expenditure testament both to the journal’s growing significance, 900 11 In 2015, we continued to collaborate with developers Revenue 2015 2014 New Reviewing and to the steady cultural shift towards greater Publishing costs The eLife Sciences from Substance and helped to introduce Lens Writer. 800 Editors transparency and collaboration in science, which lie at Grants 4,154 3,279 Technology and We also initiated a collaboration with Publons to 22% the heart of eLife’s mission. innovation 700 help give researchers credit for their peer-review Other income - 3 Annual Report 2015 600 97 contributions. Later this year, users will benefit from a Days from initial Total 4,154 3,282 submission to initial radical redesign of the entire website which has been 500 developed by the eLife product and design team. This decision* Our goal is to invest further in 400 work reflects an important part of the eLife strategy: 4 Expenses 2015 2014 Days from full eLife to enable more scientists to to research and develop new tools and methods in 300 submission to decision present their best work openly to support of open science, and to make our findings and Journal expenses 3,544 3,108 78% 200 after peer review* the world.” resources available openly so that others can benefit. Management and general 312 290 100 33 Days from initial Continuing our work with early-career researchers, Our rate of publishing almost doubled during 2015, Total 3,856 3,398 papers Number of published research 0 submission to we introduced a series of webinars about funding 2012 2013 2014 2015 reaching around 90 articles per month by the end of Publishing costs acceptance* the year, and reflecting another strong year of growth opportunities and introduced a new travel grant program to support selected early-career authors with Other Wellcome Trust in submissions. The significant and fascinating science Changes in net assets 298 (116) Payment to editors Max Planck Society Howard Hughes Medical Institute 116 published in 2015 covered the effects of moonlight on travel to meetings. 14% Online systems Net assets at beginning of year 247 363 Staff and outsourcing * Median calendar days, based on decision dates in 2015 the reproductive biology of coral, the sensation of pain Article processing Our founding funders continue to believe that eLife will 33% in human infants, the use of molecular tweezers in HIV Net assets at end of year 545 247 12% Features control, and a project in drug discovery using a citizen catalyse and inspire widespread change in the ways Marketing science approach. However, there is still far too much that scientific research is communicated and utilised. important work being published behind subscription The eLife Board is therefore excited to see strong The full audited accounts for eLife Sciences Publications Limited for barriers, and our goal is to invest further in eLife to progress with our journal and with the development 2015 are available at 2015.elifesciences.org. As a US-registered tax- exempt organisation, we also publish detailed financial information of our technology platform, both of which will help to 24% 9% Image: Maloy (CC BY 2.0) enable more scientists to benefit from the efficient in our Form 990. and rigorous eLife process and present their best work drive the kind of changes that are needed in science, 8% openly to the world. to support early-career researchers and to accelerate scientific discovery. Helping scientists accelerate discovery © 2016 eLife Sciences Publications Ltd. Subject to a Creative Commons Attribution License, except where otherwise noted. Image: Murtaugh (CC BY 2.0) JAN FEB MAR APR MAY JUN JUL AUG SEP OCT NOV DEC

eLife invites Tools and eLife adds a third Deputy Editor Researchers map disease-carrying Medium.com offers 100 digests eLife expands the editorial board eLife offers fellowship webinars Editors invite papers in eLife editors assemble Labs showcases new tools Resources papers Eve Marder, Professor of mosquitoes Between December 2014 and Another 41 scientists join the As part of its ongoing program to Around 80 eLife editors attend eLife Labs opens up to showcase eLife introduces a new article at Brandeis Scientists at the University July 2015, eLife republished a eLife Board of Reviewing Editors support early-career progression, In an editorial, ‘What makes an the annual General Assembly new tools created by external type – called Tools and Resources University, is appointed as eLife’s of Oxford predict the global selection of 100 eLife digests to (BRE), bringing expertise in 13 eLife hosts its first set of webinars eLife paper in epidemiology and in Chevy Chase, Maryland, to developers for online scientific Highlights from 2015 – to highlight new experimental third Deputy Editor. Randy distribution of mosquitoes that Medium.com, a blogging site that major subject areas and helping on postdoctoral fellowships from global health?’ editors Prabhat discuss editorial policy and the communication, through “Guest techniques, datasets, software Schekman, Editor-in-Chief, transmit dengue and chikungunya. attracts a community of readers to strengthen eLife’s consultative the Human Frontier Science Jha, Mark Jit, and Eduardo Franco state of the journal. Over two Experiments”. eLife Labs is a tools and other resources that have highlights Marder as “one of our Kraemer et al. of all interests. Digests are the approach to peer review during a Program, the Royal Society and emphasise that non-experimental days of discussions a number of platform to highlight innovative the potential to lead to important most committed champions” eLife 2015;4:e08347 non-technical summaries published steep phase of growth. the Wellcome Trust, and the U.S. papers are also welcome. “Eureka themes and actions emerged, technologies to accelerate the breakthroughs in one or more areas and welcomes her to the eLife as part of Research Articles in the National Institutes of Health. The moments exist in epidemiology; we one of the strongest being that writing, publishing, and sharing of of the sciences. leadership team. Marder regularly journal. Digests in medium are One of the 41, Ben program is informed by the eLife wish to display them prominently the consultative editorial process scientific breakthroughs. Editors describe the ideal contributes to eLife through her organised in four categories: Health Cooper, joins the eLife Early-Career Advisory Board. in eLife.” remains a unique and valuable part eLife paper eLife helps with policy compliance ‘Living Science’ series, in which and Disease, Brains and Behaviour, BRE with experience in of what eLife offers. Travel grants are introduced In a new editorial, Senior Editors The Jisc Publications Router she has written passionately on Life on Earth, Life’s Building Blocks, mathematical modelling, eLife introduces a pilot travel Vivek Malhotra and Eve Marder automates the direct delivery of topics including the use of metrics Image: Matt Berlin (CC BY SA 2.0) and Roots and Shoots. epidemiology, and grants program to help early-career explain that “the ideal eLife research articles from publishers to in research and the rewards of a global health. Ben holds scientists who have authored with paper... makes others in the field institutional repositories. eLife was career in science. Twitter gets a taste of life in an MRC Senior Research Helping scientists eLife gain exposure and recognition think differently and... should the first content provider to link the field Fellowship and is Associate for their work at scientific meetings. give the reader the pleasure of Oxford authors suggest babies up with Jisc. It helps us to provide Reviewers invited to take credit The Amboseli Baboon Research Professor at the Mahidol Oxford reading about elegant or clever accelerate our content quicker to more feel pain like adults eLife partners with Publons, a free Project takes over eLife’s Twitter Tropical Medicine Research Unit in experiments, of learning something A brain-scanning study at the destinations, and eases compliance service that makes it possible for account to offer a flavour of life Thailand. The current focus of his new, of being challenged...” University of Oxford suggests with the REF policy for authors reviewers to take credit for their outside the lab through its work in work is on combating multi-drug- discovery by babies experience pain like adults. based at UK institutions. peer-review activity. Kenya. resistant bacteria via rational use of Goksan et al. eLife 2015;4:e06356 antibiotics. operating Image: Charlop-Powers et al. (CC BY 4.0) Image: John Mayer (CC BY 2.0) RIPOSTE supports reproducibility Image: Nephron (CC BY SA 3.0) Image: Kaniewska, Alon et al. (CC BY 4.0) The introduction of RIPOSTE Epidemiology of air travel eLife editors set out their a platform Scientists at the University of (Reducing IrreProducibility in standards for excellent science California, Los Angeles, show that labOratory STudiEs), a framework The editors of eLife are working the effectiveness of airport disease developed to support early and scientists and they can put for research screening depends on several regular discussions between forward for publication as many factors and, even in the best-case scientists and statisticians in order outstanding papers as they identify. communication scenario, screening will still miss the to improve the design, conduct, To help prospective authors majority of infected passengers. and analysis of laboratory studies better understand our editors’ et al. (CC BY 4.0) Image: Berger Gostic et al. and to increase reproducibility. expectations, eLife introduces a set that encourages eLife 2015;4:e05564 of questions for authors to consider Scientists unveil new human ahead of submission and address in species and recognises the their cover letter. Scientists at the University of the Witwatersrand unearth a new species most responsible HIV tweezers of human relative in a South African Scientists at Ulm University Medical cave. The findings are jointly released Center and Perelman School of in eLife and National Geographic. behaviours in Medicine at the University of Berger et al. Scientists develop drugs from dirt eLife helps others adopt Lens New insights into tumour The of autism Bad light shed on corals Pennsylvania discover a “molecular eLife 2015;4:e09560 Analysis of soils from five continents eLife Lens is an open-source formation science. Important insights are provided into Scientists at the Australian by researchers at Rockefeller technology that improves the reading Scientists at the University of tweezer” that blocks HIV and changes to the developing brain Institute of Marine Science infection-boosting proteins in eLife supports Lens Writer University revealed top places to and use of scientific articles, as it California, Berkeley, reveal how eLife introduces Lens Writer by - The eLife mission caused by an autism-associated and Massachusetts Institute of mine untapped drugs. takes advantage of the internet’s cancer-causing mutations in the semen. gene, in two studies led by the Technology show how coral Lump, Castellano et al. Substance, the developers of eLife Charlop-Powers et al. flexibility. eLife Lens developers TERT protein-coding gene can Lens. Lens Writer is an independent University of Utah School of exposed to artificial light cannot eLife 2015;4:e05048 eLife 2015;4:e05397 from Substance and eLife discussed promote tumour formation web-based editing component Medicine and Harvard Medical detect moonlight, failing to spawn. how Lens might be extended to Chiba et al. tailored for the creation of scientific School, respectively. Kaniewska, Alon et al. eLife 2015;4:e07918 eLife 2015;4:e09991 other organisations or stages in the content, and ready to be customised Martin, Muralidhar et al. research process in a webinar. eLife 2015;4:e09395 and integrated into publishing and Tong, Hu et al. systems. eLife 2015;4:e09648 Image: Silke (CC BY 2.0) JAN FEB MAR APR MAY JUN JUL AUG SEP OCT NOV DEC

eLife invites Tools and eLife adds a third Deputy Editor Researchers map disease-carrying Medium.com offers 100 digests eLife expands the editorial board eLife offers fellowship webinars Editors invite papers in eLife editors assemble Labs showcases new tools Resources papers Eve Marder, Professor of mosquitoes Between December 2014 and Another 41 scientists join the As part of its ongoing program to Epidemiology Around 80 eLife editors attend eLife Labs opens up to showcase eLife introduces a new article Neuroscience at Brandeis Scientists at the University July 2015, eLife republished a eLife Board of Reviewing Editors support early-career progression, In an editorial, ‘What makes an the annual General Assembly new tools created by external type – called Tools and Resources University, is appointed as eLife’s of Oxford predict the global selection of 100 eLife digests to (BRE), bringing expertise in 13 eLife hosts its first set of webinars eLife paper in epidemiology and in Chevy Chase, Maryland, to developers for online scientific Highlights from 2015 – to highlight new experimental third Deputy Editor. Randy distribution of mosquitoes that Medium.com, a blogging site that major subject areas and helping on postdoctoral fellowships from global health?’ editors Prabhat discuss editorial policy and the communication, through “Guest techniques, datasets, software Schekman, Editor-in-Chief, transmit dengue and chikungunya. attracts a community of readers to strengthen eLife’s consultative the Human Frontier Science Jha, Mark Jit, and Eduardo Franco state of the journal. Over two Experiments”. eLife Labs is a tools and other resources that have highlights Marder as “one of our Kraemer et al. of all interests. Digests are the approach to peer review during a Program, the Royal Society and emphasise that non-experimental days of discussions a number of platform to highlight innovative the potential to lead to important most committed champions” eLife 2015;4:e08347 non-technical summaries published steep phase of growth. the Wellcome Trust, and the U.S. papers are also welcome. “Eureka themes and actions emerged, technologies to accelerate the breakthroughs in one or more areas and welcomes her to the eLife as part of Research Articles in the National Institutes of Health. The moments exist in epidemiology; we one of the strongest being that writing, publishing, and sharing of of the life sciences. leadership team. Marder regularly journal. Digests in medium are One of the 41, Ben program is informed by the eLife wish to display them prominently the consultative editorial process scientific breakthroughs. Editors describe the ideal contributes to eLife through her organised in four categories: Health Cooper, joins the eLife Early-Career Advisory Board. in eLife.” remains a unique and valuable part eLife paper eLife helps with policy compliance ‘Living Science’ series, in which and Disease, Brains and Behaviour, BRE with experience in of what eLife offers. Travel grants are introduced In a new editorial, Senior Editors The Jisc Publications Router she has written passionately on Life on Earth, Life’s Building Blocks, mathematical modelling, eLife introduces a pilot travel Vivek Malhotra and Eve Marder automates the direct delivery of topics including the use of metrics Image: Matt Berlin (CC BY SA 2.0) and Roots and Shoots. epidemiology, and grants program to help early-career explain that “the ideal eLife research articles from publishers to in research and the rewards of a global health. Ben holds scientists who have authored with paper... makes others in the field institutional repositories. eLife was career in science. Twitter gets a taste of life in an MRC Senior Research Helping scientists eLife gain exposure and recognition think differently and... should the first content provider to link the field Fellowship and is Associate for their work at scientific meetings. give the reader the pleasure of Oxford authors suggest babies up with Jisc. It helps us to provide Reviewers invited to take credit The Amboseli Baboon Research Professor at the Mahidol Oxford reading about elegant or clever accelerate our content quicker to more feel pain like adults eLife partners with Publons, a free Project takes over eLife’s Twitter Tropical Medicine Research Unit in experiments, of learning something A brain-scanning study at the destinations, and eases compliance service that makes it possible for account to offer a flavour of life Thailand. The current focus of his new, of being challenged...” University of Oxford suggests with the REF policy for authors reviewers to take credit for their outside the lab through its work in work is on combating multi-drug- discovery by babies experience pain like adults. based at UK institutions. peer-review activity. Kenya. resistant bacteria via rational use of Goksan et al. eLife 2015;4:e06356 antibiotics. operating Image: Charlop-Powers et al. (CC BY 4.0) Image: John Mayer (CC BY 2.0) RIPOSTE supports reproducibility Image: Nephron (CC BY SA 3.0) Image: Kaniewska, Alon et al. (CC BY 4.0) The introduction of RIPOSTE Epidemiology of air travel eLife editors set out their a platform Scientists at the University of (Reducing IrreProducibility in standards for excellent science California, Los Angeles, show that labOratory STudiEs), a framework The editors of eLife are working the effectiveness of airport disease developed to support early and scientists and they can put for research screening depends on several regular discussions between forward for publication as many factors and, even in the best-case scientists and statisticians in order outstanding papers as they identify. communication scenario, screening will still miss the to improve the design, conduct, To help prospective authors majority of infected passengers. and analysis of laboratory studies better understand our editors’ et al. (CC BY 4.0) Image: Berger Gostic et al. and to increase reproducibility. expectations, eLife introduces a set that encourages eLife 2015;4:e05564 of questions for authors to consider Scientists unveil new human ahead of submission and address in species and recognises the their cover letter. Scientists at the University of the Witwatersrand unearth a new species most responsible HIV tweezers of human relative in a South African Scientists at Ulm University Medical cave. The findings are jointly released Center and Perelman School of in eLife and National Geographic. behaviours in Medicine at the University of Berger et al. Scientists develop drugs from dirt eLife helps others adopt Lens New insights into tumour The genetics of autism Bad light shed on corals Pennsylvania discover a “molecular eLife 2015;4:e09560 Analysis of soils from five continents eLife Lens is an open-source formation science. Important insights are provided into Scientists at the Australian by researchers at Rockefeller technology that improves the reading Scientists at the University of tweezer” that blocks HIV and changes to the developing brain Institute of Marine Science infection-boosting proteins in eLife supports Lens Writer University revealed top places to and use of scientific articles, as it California, Berkeley, reveal how eLife introduces Lens Writer by - The eLife mission caused by an autism-associated and Massachusetts Institute of mine untapped drugs. takes advantage of the internet’s cancer-causing mutations in the semen. gene, in two studies led by the Technology show how coral Lump, Castellano et al. Substance, the developers of eLife Charlop-Powers et al. flexibility. eLife Lens developers TERT protein-coding gene can Lens. Lens Writer is an independent University of Utah School of exposed to artificial light cannot eLife 2015;4:e05048 eLife 2015;4:e05397 from Substance and eLife discussed promote tumour formation web-based editing component Medicine and Harvard Medical detect moonlight, failing to spawn. how Lens might be extended to Chiba et al. tailored for the creation of scientific School, respectively. Kaniewska, Alon et al. eLife 2015;4:e07918 eLife 2015;4:e09991 other organisations or stages in the content, and ready to be customised Martin, Muralidhar et al. research process in a webinar. eLife 2015;4:e09395 and integrated into publishing and Tong, Hu et al. systems. eLife 2015;4:e09648 Image: Silke (CC BY 2.0) JAN FEB MAR APR MAY JUN JUL AUG SEP OCT NOV DEC

eLife invites Tools and eLife adds a third Deputy Editor Researchers map disease-carrying Medium.com offers 100 digests eLife expands the editorial board eLife offers fellowship webinars Editors invite papers in eLife editors assemble Labs showcases new tools Resources papers Eve Marder, Professor of mosquitoes Between December 2014 and Another 41 scientists join the As part of its ongoing program to Epidemiology Around 80 eLife editors attend eLife Labs opens up to showcase eLife introduces a new article Neuroscience at Brandeis Scientists at the University July 2015, eLife republished a eLife Board of Reviewing Editors support early-career progression, In an editorial, ‘What makes an the annual General Assembly new tools created by external type – called Tools and Resources University, is appointed as eLife’s of Oxford predict the global selection of 100 eLife digests to (BRE), bringing expertise in 13 eLife hosts its first set of webinars eLife paper in epidemiology and in Chevy Chase, Maryland, to developers for online scientific Highlights from 2015 – to highlight new experimental third Deputy Editor. Randy distribution of mosquitoes that Medium.com, a blogging site that major subject areas and helping on postdoctoral fellowships from global health?’ editors Prabhat discuss editorial policy and the communication, through “Guest techniques, datasets, software Schekman, Editor-in-Chief, transmit dengue and chikungunya. attracts a community of readers to strengthen eLife’s consultative the Human Frontier Science Jha, Mark Jit, and Eduardo Franco state of the journal. Over two Experiments”. eLife Labs is a tools and other resources that have highlights Marder as “one of our Kraemer et al. of all interests. Digests are the approach to peer review during a Program, the Royal Society and emphasise that non-experimental days of discussions a number of platform to highlight innovative the potential to lead to important most committed champions” eLife 2015;4:e08347 non-technical summaries published steep phase of growth. the Wellcome Trust, and the U.S. papers are also welcome. “Eureka themes and actions emerged, technologies to accelerate the breakthroughs in one or more areas and welcomes her to the eLife as part of Research Articles in the National Institutes of Health. The moments exist in epidemiology; we one of the strongest being that writing, publishing, and sharing of of the life sciences. leadership team. Marder regularly journal. Digests in medium are One of the 41, Ben program is informed by the eLife wish to display them prominently the consultative editorial process scientific breakthroughs. Editors describe the ideal contributes to eLife through her organised in four categories: Health Cooper, joins the eLife Early-Career Advisory Board. in eLife.” remains a unique and valuable part eLife paper eLife helps with policy compliance ‘Living Science’ series, in which and Disease, Brains and Behaviour, BRE with experience in of what eLife offers. Travel grants are introduced In a new editorial, Senior Editors The Jisc Publications Router she has written passionately on Life on Earth, Life’s Building Blocks, mathematical modelling, eLife introduces a pilot travel Vivek Malhotra and Eve Marder automates the direct delivery of topics including the use of metrics Image: Matt Berlin (CC BY SA 2.0) and Roots and Shoots. epidemiology, and grants program to help early-career explain that “the ideal eLife research articles from publishers to in research and the rewards of a global health. Ben holds scientists who have authored with paper... makes others in the field institutional repositories. eLife was career in science. Twitter gets a taste of life in an MRC Senior Research Helping scientists eLife gain exposure and recognition think differently and... should the first content provider to link the field Fellowship and is Associate for their work at scientific meetings. give the reader the pleasure of Oxford authors suggest babies up with Jisc. It helps us to provide Reviewers invited to take credit The Amboseli Baboon Research Professor at the Mahidol Oxford reading about elegant or clever accelerate our content quicker to more feel pain like adults eLife partners with Publons, a free Project takes over eLife’s Twitter Tropical Medicine Research Unit in experiments, of learning something A brain-scanning study at the destinations, and eases compliance service that makes it possible for account to offer a flavour of life Thailand. The current focus of his new, of being challenged...” University of Oxford suggests with the REF policy for authors reviewers to take credit for their outside the lab through its work in work is on combating multi-drug- discovery by babies experience pain like adults. based at UK institutions. peer-review activity. Kenya. resistant bacteria via rational use of Goksan et al. eLife 2015;4:e06356 antibiotics. operating Image: Charlop-Powers et al. (CC BY 4.0) Image: John Mayer (CC BY 2.0) RIPOSTE supports reproducibility Image: Nephron (CC BY SA 3.0) Image: Kaniewska, Alon et al. (CC BY 4.0) The introduction of RIPOSTE Epidemiology of air travel eLife editors set out their a platform Scientists at the University of (Reducing IrreProducibility in standards for excellent science California, Los Angeles, show that labOratory STudiEs), a framework The editors of eLife are working the effectiveness of airport disease developed to support early and scientists and they can put for research screening depends on several regular discussions between forward for publication as many factors and, even in the best-case scientists and statisticians in order outstanding papers as they identify. communication scenario, screening will still miss the to improve the design, conduct, To help prospective authors majority of infected passengers. and analysis of laboratory studies better understand our editors’ et al. (CC BY 4.0) Image: Berger Gostic et al. and to increase reproducibility. expectations, eLife introduces a set that encourages eLife 2015;4:e05564 of questions for authors to consider Scientists unveil new human ahead of submission and address in species and recognises the their cover letter. Scientists at the University of the Witwatersrand unearth a new species most responsible HIV tweezers of human relative in a South African Scientists at Ulm University Medical cave. The findings are jointly released Center and Perelman School of in eLife and National Geographic. behaviours in Medicine at the University of Berger et al. Scientists develop drugs from dirt eLife helps others adopt Lens New insights into tumour The genetics of autism Bad light shed on corals Pennsylvania discover a “molecular eLife 2015;4:e09560 Analysis of soils from five continents eLife Lens is an open-source formation science. Important insights are provided into Scientists at the Australian by researchers at Rockefeller technology that improves the reading Scientists at the University of tweezer” that blocks HIV and changes to the developing brain Institute of Marine Science infection-boosting proteins in eLife supports Lens Writer University revealed top places to and use of scientific articles, as it California, Berkeley, reveal how eLife introduces Lens Writer by - The eLife mission caused by an autism-associated and Massachusetts Institute of mine untapped drugs. takes advantage of the internet’s cancer-causing mutations in the semen. gene, in two studies led by the Technology show how coral Lump, Castellano et al. Substance, the developers of eLife Charlop-Powers et al. flexibility. eLife Lens developers TERT protein-coding gene can Lens. Lens Writer is an independent University of Utah School of exposed to artificial light cannot eLife 2015;4:e05048 eLife 2015;4:e05397 from Substance and eLife discussed promote tumour formation web-based editing component Medicine and Harvard Medical detect moonlight, failing to spawn. how Lens might be extended to Chiba et al. tailored for the creation of scientific School, respectively. Kaniewska, Alon et al. eLife 2015;4:e07918 eLife 2015;4:e09991 other organisations or stages in the content, and ready to be customised Martin, Muralidhar et al. research process in a webinar. eLife 2015;4:e09395 and integrated into publishing and Tong, Hu et al. systems. eLife 2015;4:e09648 Image: Silke (CC BY 2.0) JAN FEB MAR APR MAY JUN JUL AUG SEP OCT NOV DEC

eLife invites Tools and eLife adds a third Deputy Editor Researchers map disease-carrying Medium.com offers 100 digests eLife expands the editorial board eLife offers fellowship webinars Editors invite papers in eLife editors assemble Labs showcases new tools Resources papers Eve Marder, Professor of mosquitoes Between December 2014 and Another 41 scientists join the As part of its ongoing program to Epidemiology Around 80 eLife editors attend eLife Labs opens up to showcase eLife introduces a new article Neuroscience at Brandeis Scientists at the University July 2015, eLife republished a eLife Board of Reviewing Editors support early-career progression, In an editorial, ‘What makes an the annual General Assembly new tools created by external type – called Tools and Resources University, is appointed as eLife’s of Oxford predict the global selection of 100 eLife digests to (BRE), bringing expertise in 13 eLife hosts its first set of webinars eLife paper in epidemiology and in Chevy Chase, Maryland, to developers for online scientific Highlights from 2015 – to highlight new experimental third Deputy Editor. Randy distribution of mosquitoes that Medium.com, a blogging site that major subject areas and helping on postdoctoral fellowships from global health?’ editors Prabhat discuss editorial policy and the communication, through “Guest techniques, datasets, software Schekman, Editor-in-Chief, transmit dengue and chikungunya. attracts a community of readers to strengthen eLife’s consultative the Human Frontier Science Jha, Mark Jit, and Eduardo Franco state of the journal. Over two Experiments”. eLife Labs is a tools and other resources that have highlights Marder as “one of our Kraemer et al. of all interests. Digests are the approach to peer review during a Program, the Royal Society and emphasise that non-experimental days of discussions a number of platform to highlight innovative the potential to lead to important most committed champions” eLife 2015;4:e08347 non-technical summaries published steep phase of growth. the Wellcome Trust, and the U.S. papers are also welcome. “Eureka themes and actions emerged, technologies to accelerate the breakthroughs in one or more areas and welcomes her to the eLife as part of Research Articles in the National Institutes of Health. The moments exist in epidemiology; we one of the strongest being that writing, publishing, and sharing of of the life sciences. leadership team. Marder regularly journal. Digests in medium are One of the 41, Ben program is informed by the eLife wish to display them prominently the consultative editorial process scientific breakthroughs. Editors describe the ideal contributes to eLife through her organised in four categories: Health Cooper, joins the eLife Early-Career Advisory Board. in eLife.” remains a unique and valuable part eLife paper eLife helps with policy compliance ‘Living Science’ series, in which and Disease, Brains and Behaviour, BRE with experience in of what eLife offers. Travel grants are introduced In a new editorial, Senior Editors The Jisc Publications Router she has written passionately on Life on Earth, Life’s Building Blocks, mathematical modelling, eLife introduces a pilot travel Vivek Malhotra and Eve Marder automates the direct delivery of topics including the use of metrics Image: Matt Berlin (CC BY SA 2.0) and Roots and Shoots. epidemiology, and grants program to help early-career explain that “the ideal eLife research articles from publishers to in research and the rewards of a global health. Ben holds scientists who have authored with paper... makes others in the field institutional repositories. eLife was career in science. Twitter gets a taste of life in an MRC Senior Research Helping scientists eLife gain exposure and recognition think differently and... should the first content provider to link the field Fellowship and is Associate for their work at scientific meetings. give the reader the pleasure of Oxford authors suggest babies up with Jisc. It helps us to provide Reviewers invited to take credit The Amboseli Baboon Research Professor at the Mahidol Oxford reading about elegant or clever accelerate our content quicker to more feel pain like adults eLife partners with Publons, a free Project takes over eLife’s Twitter Tropical Medicine Research Unit in experiments, of learning something A brain-scanning study at the destinations, and eases compliance service that makes it possible for account to offer a flavour of life Thailand. The current focus of his new, of being challenged...” University of Oxford suggests with the REF policy for authors reviewers to take credit for their outside the lab through its work in work is on combating multi-drug- discovery by babies experience pain like adults. based at UK institutions. peer-review activity. Kenya. resistant bacteria via rational use of Goksan et al. eLife 2015;4:e06356 antibiotics. operating Image: Charlop-Powers et al. (CC BY 4.0) Image: John Mayer (CC BY 2.0) RIPOSTE supports reproducibility Image: Nephron (CC BY SA 3.0) Image: Kaniewska, Alon et al. (CC BY 4.0) The introduction of RIPOSTE Epidemiology of air travel eLife editors set out their a platform Scientists at the University of (Reducing IrreProducibility in standards for excellent science California, Los Angeles, show that labOratory STudiEs), a framework The editors of eLife are working the effectiveness of airport disease developed to support early and scientists and they can put for research screening depends on several regular discussions between forward for publication as many factors and, even in the best-case scientists and statisticians in order outstanding papers as they identify. communication scenario, screening will still miss the to improve the design, conduct, To help prospective authors majority of infected passengers. and analysis of laboratory studies better understand our editors’ et al. (CC BY 4.0) Image: Berger Gostic et al. and to increase reproducibility. expectations, eLife introduces a set that encourages eLife 2015;4:e05564 of questions for authors to consider Scientists unveil new human ahead of submission and address in species and recognises the their cover letter. Scientists at the University of the Witwatersrand unearth a new species most responsible HIV tweezers of human relative in a South African Scientists at Ulm University Medical cave. The findings are jointly released Center and Perelman School of in eLife and National Geographic. behaviours in Medicine at the University of Berger et al. Scientists develop drugs from dirt eLife helps others adopt Lens New insights into tumour The genetics of autism Bad light shed on corals Pennsylvania discover a “molecular eLife 2015;4:e09560 Analysis of soils from five continents eLife Lens is an open-source formation science. Important insights are provided into Scientists at the Australian by researchers at Rockefeller technology that improves the reading Scientists at the University of tweezer” that blocks HIV and changes to the developing brain Institute of Marine Science infection-boosting proteins in eLife supports Lens Writer University revealed top places to and use of scientific articles, as it California, Berkeley, reveal how eLife introduces Lens Writer by - The eLife mission caused by an autism-associated and Massachusetts Institute of mine untapped drugs. takes advantage of the internet’s cancer-causing mutations in the semen. gene, in two studies led by the Technology show how coral Lump, Castellano et al. Substance, the developers of eLife Charlop-Powers et al. flexibility. eLife Lens developers TERT protein-coding gene can Lens. Lens Writer is an independent University of Utah School of exposed to artificial light cannot eLife 2015;4:e05048 eLife 2015;4:e05397 from Substance and eLife discussed promote tumour formation web-based editing component Medicine and Harvard Medical detect moonlight, failing to spawn. how Lens might be extended to Chiba et al. tailored for the creation of scientific School, respectively. Kaniewska, Alon et al. eLife 2015;4:e07918 eLife 2015;4:e09991 other organisations or stages in the content, and ready to be customised Martin, Muralidhar et al. research process in a webinar. eLife 2015;4:e09395 and integrated into publishing and Tong, Hu et al. systems. eLife 2015;4:e09648 Image: Silke (CC BY 2.0) Letter from the Chairman Financial summary Research supported by any funding agency 2015 by the numbers may be submitted for consideration to eLife. Toby Coppel, The funders most represented to date include Research papers the Deutsche Forschungsgemeinschaft, published The centre of the stage at eLife in 2015 was occupied Co-Founder and Partner at The grants received during the year were slightly Analysis of expenditure by a new human ancestor – Homo naledi – discovered Mosaic Ventures more than the expenditure, resulting in an increase The growth of over 50% in publishing volumes European Commission, European Research by scientists in an extraordinary find in South Africa Chair, eLife Board of Directors in net assets in the year. has led to an increase of about a third in Council, Howard Hughes Medical Institute, Max 833 and published in eLife in two stunning papers in The specific contributions from the founders were: editorial and publishing systems costs, and in Planck Society, UK Medical Research Council, Peer reviews September. The work was covered by media outlets HHMI £1.84m, Max Planck Society £0.47m and payments to editors, and these costs now also US National Institutes of Health, US National submitted Besides the progress at the journal, in 2015 there has throughout the world, not just because of the scientific Wellcome Trust £1.84m. represent a larger proportion of total costs. Science Foundation, and the Wellcome Trust. also been a great deal of work at eLife on technology significance of the discovery but also because of the There has also been a continuing substantial (Source: eLife) 5,472 and innovation. Just announced was the release of New Senior openness with which the research and its associated Statement of activities, years ended December 31 level of investment in new systems. the open-source Continuum publication platform, the Editors materials were distributed. That these scientists chose 2014 and 2015 (in £ thousands) culmination of a year-long project which has enabled 1000 to publish such ground-breaking findings in eLife is eLife to take complete control of our journal website. Total expenditure testament both to the journal’s growing significance, 900 11 In 2015, we continued to collaborate with developers Revenue 2015 2014 New Reviewing and to the steady cultural shift towards greater Publishing costs The eLife Sciences from Substance and helped to introduce Lens Writer. 800 Editors transparency and collaboration in science, which lie at Grants 4,154 3,279 Technology and We also initiated a collaboration with Publons to 22% the heart of eLife’s mission. innovation 700 help give researchers credit for their peer-review Other income - 3 Annual Report 2015 600 97 contributions. Later this year, users will benefit from a Days from initial Total 4,154 3,282 submission to initial radical redesign of the entire website which has been 500 developed by the eLife product and design team. This decision* Our goal is to invest further in 400 work reflects an important part of the eLife strategy: 4 Expenses 2015 2014 Days from full eLife to enable more scientists to to research and develop new tools and methods in 300 submission to decision present their best work openly to support of open science, and to make our findings and Journal expenses 3,544 3,108 78% 200 after peer review* the world.” resources available openly so that others can benefit. Management and general 312 290 100 33 Days from initial Continuing our work with early-career researchers, Our rate of publishing almost doubled during 2015, Total 3,856 3,398 papers Number of published research 0 submission to we introduced a series of webinars about funding 2012 2013 2014 2015 reaching around 90 articles per month by the end of Publishing costs acceptance* the year, and reflecting another strong year of growth opportunities and introduced a new travel grant program to support selected early-career authors with Other Wellcome Trust in submissions. The significant and fascinating science Changes in net assets 298 (116) Payment to editors Max Planck Society Howard Hughes Medical Institute 116 published in 2015 covered the effects of moonlight on travel to meetings. 14% Online systems Net assets at beginning of year 247 363 Staff and outsourcing * Median calendar days, based on decision dates in 2015 the reproductive biology of coral, the sensation of pain Article processing Our founding funders continue to believe that eLife will 33% in human infants, the use of molecular tweezers in HIV Net assets at end of year 545 247 12% Features control, and a project in drug discovery using a citizen catalyse and inspire widespread change in the ways Marketing science approach. However, there is still far too much that scientific research is communicated and utilised. important work being published behind subscription The eLife Board is therefore excited to see strong The full audited accounts for eLife Sciences Publications Limited for barriers, and our goal is to invest further in eLife to progress with our journal and with the development 2015 are available at 2015.elifesciences.org. As a US-registered tax- exempt organisation, we also publish detailed financial information of our technology platform, both of which will help to 24% 9% Image: Maloy (CC BY 2.0) enable more scientists to benefit from the efficient in our Form 990. and rigorous eLife process and present their best work drive the kind of changes that are needed in science, 8% openly to the world. to support early-career researchers and to accelerate scientific discovery. Helping scientists accelerate discovery © 2016 eLife Sciences Publications Ltd. Subject to a Creative Commons Attribution License, except where otherwise noted. Image: Murtaugh (CC BY 2.0) Letter from the Chairman Financial summary Research supported by any funding agency 2015 by the numbers may be submitted for consideration to eLife. Toby Coppel, The funders most represented to date include Research papers the Deutsche Forschungsgemeinschaft, published The centre of the stage at eLife in 2015 was occupied Co-Founder and Partner at The grants received during the year were slightly Analysis of expenditure by a new human ancestor – Homo naledi – discovered Mosaic Ventures more than the expenditure, resulting in an increase The growth of over 50% in publishing volumes European Commission, European Research by scientists in an extraordinary find in South Africa Chair, eLife Board of Directors in net assets in the year. has led to an increase of about a third in Council, Howard Hughes Medical Institute, Max 833 and published in eLife in two stunning papers in The specific contributions from the founders were: editorial and publishing systems costs, and in Planck Society, UK Medical Research Council, Peer reviews September. The work was covered by media outlets HHMI £1.84m, Max Planck Society £0.47m and payments to editors, and these costs now also US National Institutes of Health, US National submitted Besides the progress at the journal, in 2015 there has throughout the world, not just because of the scientific Wellcome Trust £1.84m. represent a larger proportion of total costs. Science Foundation, and the Wellcome Trust. also been a great deal of work at eLife on technology significance of the discovery but also because of the There has also been a continuing substantial (Source: eLife) 5,472 and innovation. Just announced was the release of New Senior openness with which the research and its associated Statement of activities, years ended December 31 level of investment in new systems. the open-source Continuum publication platform, the Editors materials were distributed. That these scientists chose 2014 and 2015 (in £ thousands) culmination of a year-long project which has enabled 1000 to publish such ground-breaking findings in eLife is eLife to take complete control of our journal website. Total expenditure testament both to the journal’s growing significance, 900 11 In 2015, we continued to collaborate with developers Revenue 2015 2014 New Reviewing and to the steady cultural shift towards greater Publishing costs The eLife Sciences from Substance and helped to introduce Lens Writer. 800 Editors transparency and collaboration in science, which lie at Grants 4,154 3,279 Technology and We also initiated a collaboration with Publons to 22% the heart of eLife’s mission. innovation 700 help give researchers credit for their peer-review Other income - 3 Annual Report 2015 600 97 contributions. Later this year, users will benefit from a Days from initial Total 4,154 3,282 submission to initial radical redesign of the entire website which has been 500 developed by the eLife product and design team. This decision* Our goal is to invest further in 400 work reflects an important part of the eLife strategy: 4 Expenses 2015 2014 Days from full eLife to enable more scientists to to research and develop new tools and methods in 300 submission to decision present their best work openly to support of open science, and to make our findings and Journal expenses 3,544 3,108 78% 200 after peer review* the world.” resources available openly so that others can benefit. Management and general 312 290 100 33 Days from initial Continuing our work with early-career researchers, Our rate of publishing almost doubled during 2015, Total 3,856 3,398 papers Number of published research 0 submission to we introduced a series of webinars about funding 2012 2013 2014 2015 reaching around 90 articles per month by the end of Publishing costs acceptance* the year, and reflecting another strong year of growth opportunities and introduced a new travel grant program to support selected early-career authors with Other Wellcome Trust in submissions. The significant and fascinating science Changes in net assets 298 (116) Payment to editors Max Planck Society Howard Hughes Medical Institute 116 published in 2015 covered the effects of moonlight on travel to meetings. 14% Online systems Net assets at beginning of year 247 363 Staff and outsourcing * Median calendar days, based on decision dates in 2015 the reproductive biology of coral, the sensation of pain Article processing Our founding funders continue to believe that eLife will 33% in human infants, the use of molecular tweezers in HIV Net assets at end of year 545 247 12% Features control, and a project in drug discovery using a citizen catalyse and inspire widespread change in the ways Marketing science approach. However, there is still far too much that scientific research is communicated and utilised. important work being published behind subscription The eLife Board is therefore excited to see strong The full audited accounts for eLife Sciences Publications Limited for barriers, and our goal is to invest further in eLife to progress with our journal and with the development 2015 are available at 2015.elifesciences.org. As a US-registered tax- exempt organisation, we also publish detailed financial information of our technology platform, both of which will help to 24% 9% Image: Maloy (CC BY 2.0) enable more scientists to benefit from the efficient in our Form 990. and rigorous eLife process and present their best work drive the kind of changes that are needed in science, 8% openly to the world. to support early-career researchers and to accelerate scientific discovery. Helping scientists accelerate discovery © 2016 eLife Sciences Publications Ltd. Subject to a Creative Commons Attribution License, except where otherwise noted. Image: Murtaugh (CC BY 2.0)