Rabies (English)
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Antibody-Mediated Enhancement of Rabies Virus
542 Nature Vol. 290 16 April 1981 rearranged, K-chain gene, for example; region than the salivary gland mRNA. It is Are these findings at all relevant to the only one of these is destined to appear in possible that this affects the translation rabies 'early death' effect? Rabies viruses the mRNA, the remainder being removed efficiences of the mRNA (see 'Discussion' were thought to be serologically identical, by differential splicing. in Young et al.). Although the explanation but a number of rabies-related viruses are Why does the mouse go to all this for this fascinating genetic mechanism is now knownl2 , and antigenic variation trouble? Any explanation should consider the subject of future work, it is, of course, between rabies virus strains has been estab the fact that a-amylase mRNA accounts likely to be tied up with the primary lished I3 • Mice inoculated with Lagos Bat or for 2 per cent of the cytoplasmic mRNA in question - what determines the different Mokola viruses, two of the rabies-related the salivary gland, but only 0.02 per cent in level of a-amylase in two different tissues? viruses, and subsequently challenged with liver. This level may reflect the transcrip In the rat (and other mammals) the rabies virus, also died more quicklyl4. tion rate from the two genes; the 'salivary situation may be even more complicated. These findings suggest that it is not gland' promoter would then be consider MacDonald and his co-workers (Nature essential to have homologous neutralizing ably stronger than the 'liver' promoter. 287, 17; 1980) have analysed the rat antibodies to produce the rabies 'early Alternatively, the rate of RNA processing a-amylase genes and these studies point to death' effect, but that cross-reacting sera andlor export to the cytoplasm may be at least five non-allelic a-amylase genes or may also be active in this system as in the different for the two mRNAs. -
Animal Shelters List by County
MICHIGAN REGISTERED ANIMAL SHELTERS BY COUNTY COUNTY FACILITY NAME FACILITY ADDRESS CITY ZIP CODE PHONE Alcona ALCONA HUMANE SOCIETY 457 W TRAVERSE BAY STATE RD LINCOLN 48742 (989) 736-7387 Alger ALGER COUNTY ANIMAL SHELTER 510 E MUNISING AVE MUNISING 49862 (906) 387-4131 Allegan ALLEGAN COUNTY ANIMAL SHELTER 2293 33RD STREET ALLEGAN 49010 (269) 673-0519 COUNTRY CAT LADY 3107 7TH STREET WAYLAND 49348 (616) 308-3752 Alpena ALPENA COUNTY ANIMAL CONTROL 625 11th STREET ALPENA 49707 (989) 354-9841 HURON HUMANE SOCIETY, INC. 3510 WOODWARD AVE ALPENA 49707 (989) 356-4794 Antrim ANTRIM COUNTY ANIMAL CONTROL 4660 M-88 HWY BELLAIRE 49615 (231) 533-6421 ANTRIM COUNTY PET AND ANIMAL WATCH 125 IDA ST MANCELONA 49659 (231) 587-0738 HELP FROM MY FRIENDS, INC. 3820 RITT ROAD BELLAIRE 49615 (231) 533-4070 Arenac ARENAC COUNTY ANIMAL CONTROL SHELTER 3750 FOCO ROAD STANDISH 48658 (989) 846-4421 Barry BARRY COUNTY ANIMAL CONTROL SHELTER 540 N INDUSTRIAL PARK DR HASTINGS 49058 (269) 948-4885 Bay BAY COUNTY ANIMAL CONTROL SHELTER 800 LIVINGSTON BAY CITY 48708 (989) 894-0679 HUMANE SOCIETY OF BAY COUNTY 1607 MARQUETTE AVE BAY CITY 48706 (989) 893-0451 Benzie BENZIE COUNTY ANIMAL CONTROL SHELTER 543 S MICHIGAN AVE BEULAH 49617 (231) 882-9505 TINA'S BED AND BISCUIT INC 13030 HONOR HWY BEULAH 49617 (231) 645-8944 Berrien BERRIEN COUNTY ANIMAL SHELTER 1400 S EUCLID AVE BENTON HARBOR 49022 (269) 927-5648 HUMANE SOCIETY - SOUTHWESTERN MICHIGAN 5400 NILES AVE ST JOSEPH 49085 (269) 927-3303 Branch BRANCH COUNTY ANIMAL SHELTER 375 KEITH WILHELM DR COLDWATER 49036 (517) 639-3210 HUMANE SOCIETY OF BRANCH COUNTY, INC. -
National Specialty Insurance Company Boost Pet Health Insurance Program
National Specialty Insurance Company Boost Pet Health Insurance Program Countrywide Rating Manual Section I: General Rules A. Application of Manual 1. The rules contained in these pages will govern the rating of the Pet Health Insurance Plan policies. 2. The Pet Health Insurance Plan contains multiple benefit and coverage options. Unique benefit packages can be designed by constructing combinations of these benefit and coverage options. B. Premium Computation 1. Premiums at policy inception will be computed using the rules, rates and rating plan in effect at that time. 2. Premiums are calculated for each benefit package. 3. To calculate the monthly rate, divide the annual rate by 12, and then round to two decimal places. 4. To meet the demand of a marketable price point, a downward adjustment in price, not to exceed 5%, may be applied to the monthly premium. C. Additional Premium Charges 1. Additional premiums are computed using rates in effect at policy inception. 2. All coverage changes or additions involving additional premiums will be pro-rated based upon the effective date of the change. 3. If an endorsement or change to a policy results in an additional premium of $5 or less, no charge will be made. D. Return Premiums 1. Return premiums are computed using rates in effect at policy inception. 2. All coverage changes involving return premiums will be pro-rated based upon the effective date of the change. 3. If an endorsement or change to a policy results in a return premium of $5 or less, no return will be made. E. Minimum Premium The minimum premium per year is $50.00. -
Peninsula Humane Society & SPCA Now Offering Popular Paws for Tales Program Virtually
Tom and Annette Lantos Center for Compassion 1450 Rollins Road, Burlingame, CA 94010-2307 650-340-7022 • 650-685-8428 fax • www.PHS-SPCA.org FOR IMMEDIATE RELEASE August 6, 2020 Peninsula Humane Society & SPCA Now Offering Popular Reading to Dogs Program Virtually Burlingame, CA –The Peninsula Humane Society & SPCA (PHS/SPCA) in partnership with the Redwood City Public Library, San Mateo Main Library and branches in the San Mateo County Library system is now offering their very popular free of charge Paws for Tales reading program virtually. “Our Paws for Tales program helps children who are experiencing difficulty or shyness when reading,” said PHS/SPCA Communications Manager Buffy Martin-Tarbox. “It’s a simple but effective program where a child reads a book out loud to perhaps the most non-judgmental being on the planet: a Pet Assisted Therapy dog. Normally we offer the program in-person at the libraries, but due to the COVID-19 pandemic and the shelter-in-place order, Paws for Tales is now available via Zoom.” Paws for Tales is free and affords young readers the opportunity to practice their reading and speaking skills. The youth take turns reading out loud to a PHS/SPCA Pet Assisted Therapy dog. PHS/SPCA Assisted Therapy program is made up of San Mateo County residents and their pets who undergo rigorous training and health checks before being certified. After certification, the Pet Assisted Therapy teams provide in-person visits to health care facilities, drug rehabilitation centers, schools, libraries and correctional facilities. The in-person visits are temporarily suspended at this time. -
Bite, Rabies, and Quarantine Information
Rabies and Vaccinations Rabies is a disease caused by a virus (Lyssavirus) found in the saliva of infected animals and is transmitted to other warm- blooded animals, including humans by a bite, scratch or through an open cut. The virus infects Always be alert and know your dog. Watch for signs your dog the central nervous system, causing swelling in is uncomfortable or feeling aggressive and be on the the brain and ultimately death. lookout for potentially dangerous situations. To protect the public, California requires Animal Services to quarantine dogs and cats that have: bitten a human causing a break in the skin, were imported, or exposed to potentially rabid animals, for signs of rabies, for a minimum of 10 days. Dogs are required to be vaccinated for rabies at four months of age. Cats can be vaccinated as early as three months. The first rabies vaccine is What happens during a quarantine? If a dog bite occurs effective for one year. After that initial shot, your Your pet will be placed under quarantine (isolation) 1. Move victim to a safe area. pet should be re-vaccinated every three years. for 10 days to be observed for signs of rabies; this 2. Thoroughly wash the wound with soap and warm Rabies Vaccinations are inexpensive and must allows Animal Services to contain possible rabies water. be administered by a licensed veterinarian. outbreaks. Quarantine can be done at your home if 3. Seek advanced medical aid if necessary; call 9-1-1. Check with Hesperia Animal Services or your authorities are satisfied with the containment area, 4. -
Characterizing and Evaluating the Zoonotic Potential of Novel Viruses Discovered in Vampire Bats
viruses Article Characterizing and Evaluating the Zoonotic Potential of Novel Viruses Discovered in Vampire Bats Laura M. Bergner 1,2,* , Nardus Mollentze 1,2 , Richard J. Orton 2 , Carlos Tello 3,4, Alice Broos 2, Roman Biek 1 and Daniel G. Streicker 1,2 1 Institute of Biodiversity, Animal Health and Comparative Medicine, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow G12 8QQ, UK; [email protected] (N.M.); [email protected] (R.B.); [email protected] (D.G.S.) 2 MRC–University of Glasgow Centre for Virus Research, Glasgow G61 1QH, UK; [email protected] (R.J.O.); [email protected] (A.B.) 3 Association for the Conservation and Development of Natural Resources, Lima 15037, Peru; [email protected] 4 Yunkawasi, Lima 15049, Peru * Correspondence: [email protected] Abstract: The contemporary surge in metagenomic sequencing has transformed knowledge of viral diversity in wildlife. However, evaluating which newly discovered viruses pose sufficient risk of infecting humans to merit detailed laboratory characterization and surveillance remains largely speculative. Machine learning algorithms have been developed to address this imbalance by ranking the relative likelihood of human infection based on viral genome sequences, but are not yet routinely Citation: Bergner, L.M.; Mollentze, applied to viruses at the time of their discovery. Here, we characterized viral genomes detected N.; Orton, R.J.; Tello, C.; Broos, A.; through metagenomic sequencing of feces and saliva from common vampire bats (Desmodus rotundus) Biek, R.; Streicker, D.G. and used these data as a case study in evaluating zoonotic potential using molecular sequencing Characterizing and Evaluating the data. -
Rabies Information for Dog Owners
Rabies Information for Dog Owners Key Facts Disease in dogs: • During initial days of illness, signs can be nonspecific, such as fever, anxiety and consumption of foreign items (e.g. blankets) • Progresses to more severe signs, such as: • Behavioral change (e.g. aggression, excitability) • Incoordination, loss of balance, disorientation, weakness • Hypersalivation • Seizures • Death results within 10 days of first signs of illness Rabies in dogs is not treatable. Vaccination is key to prevention: • Rabies vaccines are protective if given before exposure to the rabies virus. • Proof of dog vaccination is mandated by many jurisdictions and required for international travel. • Dogs not current on vaccination that are likely exposed to the rabies virus may be required to be euthanized or undergo a long and expensive quarantine. What is it? Rabies is caused by infection with the rabies virus. In North America, the most common wildlife rabies The virus lives in various species of mammals and species (termed reservoirs) vary regionally and is most commonly spread through bites from one include raccoons, skunks, foxes, coyotes, and animal to another or to a human (i.e. in an infected bats. Each year in the United States over 4,000 animal’s saliva). rabid animals are reported, including several Disease in dogs may begin with vague signs of hundred rabid dogs and cats, other domestic illness, but rapidly progresses to severe neurologic species (e.g., horses, cattle, sheep, goats) and signs (e.g. aggression, incoordination). Typically, thousands of wildlife animals. death occurs within 10 days of the first signs of illness. Where is it? The rabies virus is present in nearly all parts of the world. -
Annual Report
OTTAWA HUMANE SOCIETY 2019•20 ANNUAL REPORT YOU give so many homeless and injured animals a second chance at a better life. Thank you for rescuing, reuniting and rehoming Ottawa’s most vulnerable animals. Mission: To lead Ottawa in building a humane and compassionate community for all animals. By the Numbers: You Save Lives Veterinarians performed 2,804 surgeries on animals in the care of the Ottawa Humane Society last year. They completed: Spays and Dental Diagnostic 2,804 neuters procedures X-rays procedures Surgeries 2,622 541 761 210 In the Nick of Time Last November, Elsie, a After the surgery, Elsie was beautiful chocolate lab, wrapped in a warm blanket was rushed to the OHS. and left to gently wake up in She was dehydrated and critical care. The surgery may malnourished from refusing have been a success, but there to eat for two weeks. were still many steps on her She was suffering from road to recovery. She needed the advanced stages of medications, dental care and pyometra — an infection of tests to check for side effects the uterus that is fatal if left from the surgery. untreated. Elsie’s condition was critical but thanks to Thanks to you, Elsie’s story you, she was given hope. has a happy ending. Once she was fully healed, the There was little time. OHS OHS made her available for veterinarians had to act fast. adoption and she soon went Elsie’s entire uterus had to be removed along with home with her forever family. From the surgery, to the all the pus built up from the infection. -
Pet Cats & Human Health Things to Think About Before Getting a Cat
For Pet \ Owners Pet Cats & Human Health As of 2000, it was estimated that there were approximately 4.5 million domestic cats in Canadian homes. Many cat owners live in very close contact with their feline companions. It is common for house cats to have access to areas like the kitchen counter where food is prepared, and many cats sleep in the same bed as their owners. Given the high frequency of very close contact between cats and people, it is easy to see how infection could be transmitted between them. Although the risk of zoonotic disease transmission from cats is very low, it is important to be aware that it exists, and to take some simple precautions to reduce this risk. Things to Think About Before Getting a Cat Your veterinarian is a great source of information and advice about the time and financial commitments involved in owning a cat what kind of cat would be best suited for you and from where you should get one. In order to decrease the risk of your cat becoming sick and/or transmitting infection to a person, it is recommended that the cat should be: Well socialized and accustomed to handling: this will make the cat less likely to bite or scratch a person. Examined regularly by a veterinarian: in order to assess the overall health of the cat, check for external and internal parasites, and clip the cat’s claws. Declawing the cat is NOT necessary. Spayed/neutered: this will help to decrease fighting with other cats and the tendency to roam, as well as the tendency for male cats to urine mark, and it eliminates the possibility of pregnancy in female cats. -
Savannah Cat’ ‘Savannah the Including Serval Hybrids Felis Catus (Domestic Cat), (Serval) and (Serval) Hybrids Of
Invasive animal risk assessment Biosecurity Queensland Agriculture Fisheries and Department of Serval hybrids Hybrids of Leptailurus serval (serval) and Felis catus (domestic cat), including the ‘savannah cat’ Anna Markula, Martin Hannan-Jones and Steve Csurhes First published 2009 Updated 2016 © State of Queensland, 2016. The Queensland Government supports and encourages the dissemination and exchange of its information. The copyright in this publication is licensed under a Creative Commons Attribution 3.0 Australia (CC BY) licence. You must keep intact the copyright notice and attribute the State of Queensland as the source of the publication. Note: Some content in this publication may have different licence terms as indicated. For more information on this licence visit http://creativecommons.org/licenses/ by/3.0/au/deed.en" http://creativecommons.org/licenses/by/3.0/au/deed.en Front cover: Close-up of a 4-month old F1 Savannah cat. Note the occelli on the back of the relaxed ears, and the tear-stain markings which run down the side of the nose. Photo: Jason Douglas. Image from Wikimedia Commons under a Public Domain Licence. Invasive animal risk assessment: Savannah cat Felis catus (hybrid of Leptailurus serval) 2 Contents Introduction 4 Identity of taxa under review 5 Identification of hybrids 8 Description 10 Biology 11 Life history 11 Savannah cat breed history 11 Behaviour 12 Diet 12 Predators and diseases 12 Legal status of serval hybrids including savannah cats (overseas) 13 Legal status of serval hybrids including savannah cats -
Everything You Always Wanted to Know About Rabies Virus ♣♣♣♣♣♣♣♣♣♣♣♣♣♣♣♣♣♣♣♣♣ (But Were Afraid to Ask) Benjamin M
ANNUAL REVIEWS Further Click here to view this article's online features: t%PXOMPBEmHVSFTBT115TMJEFT t/BWJHBUFMJOLFESFGFSFODFT t%PXOMPBEDJUBUJPOT Everything You Always Wanted t&YQMPSFSFMBUFEBSUJDMFT t4FBSDILFZXPSET to Know About Rabies Virus (But Were Afraid to Ask) Benjamin M. Davis,1 Glenn F. Rall,2 and Matthias J. Schnell1,2,3 1Department of Microbiology and Immunology and 3Jefferson Vaccine Center, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, Pennsylvania, 19107; email: [email protected] 2Fox Chase Cancer Center, Philadelphia, Pennsylvania 19111 Annu. Rev. Virol. 2015. 2:451–71 Keywords First published online as a Review in Advance on rabies virus, lyssaviruses, neurotropic virus, neuroinvasive virus, viral June 24, 2015 transport The Annual Review of Virology is online at virology.annualreviews.org Abstract This article’s doi: The cultural impact of rabies, the fatal neurological disease caused by in- 10.1146/annurev-virology-100114-055157 fection with rabies virus, registers throughout recorded history. Although Copyright c 2015 by Annual Reviews. ⃝ rabies has been the subject of large-scale public health interventions, chiefly All rights reserved through vaccination efforts, the disease continues to take the lives of about 40,000–70,000 people per year, roughly 40% of whom are children. Most of Access provided by Thomas Jefferson University on 11/13/15. For personal use only. Annual Review of Virology 2015.2:451-471. Downloaded from www.annualreviews.org these deaths occur in resource-poor countries, where lack of infrastructure prevents timely reporting and postexposure prophylaxis and the ubiquity of domestic and wild animal hosts makes eradication unlikely. Moreover, al- though the disease is rarer than other human infections such as influenza, the prognosis following a bite from a rabid animal is poor: There is cur- rently no effective treatment that will save the life of a symptomatic rabies patient. -
Birmans: What a Unique Breed! PET MEDICAL CENTER
Birmans: What a Unique Breed! Your cat is special! She senses your moods, is curious about your day, and has purred her way into your heart. Chances are that you chose her because you like Birmans (sometimes called “Mitted Cats”) and you expected her to have certain traits that would fit your lifestyle, like: Might "chirrup" or trill her meows to call you when she misses you An affectionate companion and family cat Good with children and other pets Requires minimal grooming Excellent companion However, no cat is perfect! You may have also noticed these characteristics: Needs regular exercise and diet regulation to avoid weight gain Needs the company of other pets or people and does not do well in isolation Exhibits signs of separation anxiety if left alone too much Is it all worth it? Of course! She's full of personality, and you love her for it! She is gentle, friendly and loves to be involved in your daily activities. The origin of the Birman remains a mystery with many unverified tales of their beginnings. Born all white, Birmans do not develop their full color until maturity. They keep their unique white “mittens” on all four paws. Birmans are very social and happy to be involved in your daily activities. They are less apt to climb and jump onto high places, preferring to hang out at ground level or on the couch. Birmans have a playful side and will play fetch or chase when engaged, but prefer to lounge with their family. PET MEDICAL CENTER 501 E. FM 2410 ● Harker Heights, Texas 76548 (254) 690-6769 www.pet-medcenter.com cat's dietary habits is key.