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Bioengineering and Biosensors 2017 conferenceseries.com 1248th Conference 5th International summit on Medical Biology & Bioengineering & 8th International Conference & Exhibition on Biosensors and Bioelectronics September 27-28, 2017 Chicago, USA Keynote Forum DAY 1 Bioengineering and Biosensors 2017 Page 21 Mahmoud F Almasri, J Bioengineer & Biomedical Sci 2017, 7:4 (Suppl) conferenceseries.com DOI: 10.4172/2155-9538-C1-016 5th International summit on Medical Biology & Bioengineering 8th International Conference & Exhibition on & September 27-28, 2017 Biosensors and Bioelectronics Chicago, USA Mahmoud F Almasri University of Missouri, USA An impedance biosensor for rapid detection of low concentration of Escherichia coli O157:H7 his presentation will provide an overview of the food safety testing requirements for ready to eat (RTE) food, and raw T(NRTE) food, and will discuss the recent impedance biosensor developments in my group for rapid and simultaneous detection of single and multi-pathogens in poultry. The device initially focuses and concentrates the bacteria into the centerline of the microchannel, and directs them toward the sensing region. The bulk media will be directed to the waste outlets through the outer channel. The bacteria will then be trapped on top of the sensing region using trapping electrodes which confine and facilitate the contact and binding of salmonella antigens with salmonella antibody immobilized on the detection electrodes. Various low concentration E.coli and Salmonella samples were tested with and without the trapping electrodes to determine the sensitivity of the biosensor. The lowest measured concentration of Salmonella cells was found to be 13 cell/ml with a detection time of 30 minutes. Biography Mahmoud Almasri received BSc and MSc degrees in physics from Bogazici University, Istanbul, Turkey, in 1995 and 1997, respectively, and a PhD in electrical engineering from Southern Methodist University (SMU), Dallas, TX, in 2001. He is currently an associate professor with the Department of Electrical Engineering and Computer Science, University of Missouri. From 2001 to 2002 he was a research scientist with General Monitors, Lake Forest CA. From 2002 to 2003 he was with College of Nanoscale Science and Engineering Albany, NY, as a post doctoral research associate, and from 2004 to 2005 he was with Georgia Institute of Technology as a post doctoral fellow, and a research scientist. His current research include impedance biosensors, MEMS capacitors for power harvesting, Si-Ge-O infrared material, metasurface based uncooled IR detectors, and MEMS Coulter counter for studying time sensitive cell. His research is funded by agencies such as NSF, USDA, ARO, Leonard Wood Institute, and Coulter Foundation. [email protected] Notes: J Bioengineer & Biomedical Sci, an open access journal Bioengineering and Biosensors 2017 Volume 7, Issue 4 (Suppl) ISSN: 2155-9538 September 27-28, 2017 Page 22 Manh-Huong Phan, J Bioengineer & Biomedical Sci 2017, 7:4 (Suppl) conferenceseries.com DOI: 10.4172/2155-9538-C1-016 5th International summit on Medical Biology & Bioengineering 8th International Conference & Exhibition on & September 27-28, 2017 Biosensors and Bioelectronics Chicago, USA Manh-Huong Phan University of South Florida, USA Recent developments in magnetic impedance biosensors and related medical devices arly detection of cancer cells in the body greatly increases the chances of successful treatment. While traditional methods, Esuch as visual identification of malignant changes, cell growth analysis, specific-ligand receptor labeling, or genetic testing often require lengthy analysis, a combination of ultrasensitive magnetic field sensors with functionalized magnetic nanoparticles offers a promising approach for a highly sensitive, simple, and quick detection of cancer cells and biomolecules. In this talk, I will review recent progress in the development of magnetic impedance biosensors using nanoparticles. I will present a new approach that integrates the magneto-resistance (MR), magneto-reactance (MX), and magneto-impedance (MI) effects to develop a functional magnetic biosensor with tunable and enhanced sensitivity. The MX-based probe shows the most sensitive detection of superparamagnetic nanoparticles (~10 nm diameter) at low concentrations. A novel biosensor based on the MX effect of a soft ferromagnetic ribbon with a microhole-patterned surface has been developed, demonstrating its high capacity for the detection and quantification of anticancer drugs and proteins tagged to Fe3O4 nanoparticles, as well as Lewis lung carcinoma (LLC) cancer cells that have taken up Fe3O4 or MnO nanoparticles. Finite element simulation fully supports the experimental observations. Finally, novel classes of magnetic nanostructures for advanced biosensing and new exploration in medical diagnostics will be discussed. Biography Manh-Huong Phan has obtained a global education with BS, MS and PhD degrees in Physics from Vietnam National University (2000), Chungbuk National (2003), and Bristol University – United Kingdom (2006), respectively. He is an Associate Professor of Physics at the University of South Florida. He has published more than 230 peer-reviewed journal papers (h-index: 37 from Google Scholar) and one text book. He is an Associate Editor for the Journal of Electronic Materials and the Managing Editor for the Journal of Science: Advanced Materials and Devices. [email protected] Notes: J Bioengineer & Biomedical Sci, an open access journal Bioengineering and Biosensors 2017 Volume 7, Issue 4 (Suppl) ISSN: 2155-9538 September 27-28, 2017 Page 23 David W Schmidtke, J Bioengineer & Biomedical Sci 2017, 7:4 (Suppl) conferenceseries.com DOI: 10.4172/2155-9538-C1-016 5th International summit on Medical Biology & Bioengineering 8th International Conference & Exhibition on & September 27-28, 2017 Biosensors and Bioelectronics Chicago, USA David W Schmidtke University of Texas, USA Novel redox polymer films for biosensing and biofuel cell applications olecular wiring of the redox centers of enzymes to electrode surfaces via redox polymers has attracted considerable Mattention due to its use in developing biosensors for metabolic monitoring of glucose in diabetes, detection of hybridization reactions in RNA and DNA assays, antigen-antibody binding in immunoassays, and in miniaturize biofuel cells. However for these devices to be useful their sensitivity and lifetime must be sufficient for them to be operated by portable low-cost electronics. This talk will describe our research on the design of a new class of redox polymers based on attaching ferrocene (Fc) redox centers to linear polyethyleneimine (LPEI). We will provide an overview of how the polymer and redox center structure affects their stability, redox potential, and ability to electrically communicate with enzyme redox centers? We will discuss, how these novel redox polymers can electrically communicate with the redox centers of a variety of enzymes (e.g. glucose oxidase, horseradish peroxidase, fructose dehydrogenase) and generate bioelectrocatalytic current densities >1 mA/ cm2? Finally, we will discuss how these redox polymers can be combined with the unique properties of Single-Walled Carbon Nanotubes (SWNTs) for both biosensing and enzymatic biofuel cell applications?. Biography David W Schmidtke is a Professor of Bioengineering at the University of Texas at Dallas (UT-Dallas). He has received his PhD in Chemical Engineering from the University of Texas at Austin and completed his Postdoctoral studies in the Institute of Medicine and Engineering at the University of Pennsylvania. Prior to joining UT-Dallas, he was a Professor of Chemical Engineering at the University of Oklahoma, and served as the Director of the University of Oklahoma Bioengineering Center. He has been a recipient of both an American Heart Association Scientist Development Award and a National Science Foundation CAREER Award. [email protected] Notes: J Bioengineer & Biomedical Sci, an open access journal Bioengineering and Biosensors 2017 Volume 7, Issue 4 (Suppl) ISSN: 2155-9538 September 27-28, 2017 Page 24 Yingxu Wang, J Bioengineer & Biomedical Sci 2017, 7:4 (Suppl) conferenceseries.com DOI: 10.4172/2155-9538-C1-016 5th International summit on Medical Biology & Bioengineering 8th International Conference & Exhibition on & September 27-28, 2017 Biosensors and Bioelectronics Chicago, USA Yingxu Wang University of Calgary, Canada From bioengineering and cognitive engineering to brain inspired systems he ultimate universe of discourse of the natural world can be perceived as a parallel dual encompassing the concrete and Tabstract worlds. The former is studied at the chemical, physical, biological, physiological, brain, and sociological layers. However, the latter is studied at data, information, knowledge and intelligence layers underpinned by mathematics as the general abstract science. Bioengineering is a trans-biological-and-engineering filed that solves organic, life, body and brain problems as well as medical, agricultural and socioeconomical applications at the molecular, gene and neural levels. Cognitive engineering is an adjacent layer beyond bioengineering that study cognitive and brain-inspired systems based on cognitive and intelligence sciences. Both biological and cognitive engineering leads to brain-inspired systems and AI applications which are bioengineered and cognitively implemented mimicking the brain and the natural intelligence. Latest basic studies reveal that novel solutions to fundamental
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