CURRICULUM VITAE

Kiana Aran [email protected] Associate Professor of Biosciences Tel (909) 607-8512 School of Applied Life Sciences Keck Graduate Institute, Claremont University, Claremont, CA, 91711

Visiting Assistant Professor Department of Bioengineering, University of , Berkeley, CA 94720

EDUCATION Postdoc (Oct 2015-Dec 2016) Buck Institute for Research on Aging Postdoc (Oct 2012-Dec 2016) Bioengineering, UC Berkeley Ph.D. (Sep 2007-Jan 2012) Biomedical Engineering, Rutgers University B.S. (Sep 2003-May 2007) Electrical Engineering, City University of New York

SUMMARY OF PROFESSIONAL ACTIVITIES

Henry E. Riggs School of Applied Life Sciences, Keck Graduate Institute, Claremont University, CA, 91711. Associate Professor (May 2021 to present); Assistant Professor (Jan 2017 to May 2021); Director of High School Summer STEM Program (May 2017 to present)

Bioengineering Department, UC Berkeley, CA, 94720 Visiting Researcher (July 2017 to present)

Co-founder, Nanosens Innovations Inc., San Diego, CA, 92121 (Aug 2018 to present)

Co-founder, Cardea Bio Inc., San Diego, CA, 92121 (Sep 2019 to present)

Chief Scientific Officer, Cardea Bio Inc., San Diego, CA, 92121 (Sep 2019 to present)

Scientific Panel Reviewer, National Institutes of Health (Nov 2020 to present)

Scientific Panel Reviewer, National Science Foundation (Oct 2020 to present)

Reviewer, Nature Biomedical Engineering (May 2019 to present)

Reviewer, Analytical Chemistry (Apr 2020 to present)

Reviewer, Biosensors and Bioelectronics (Nov 2019 to present)

Guest Editor, Biosensors and Bioelectronics, Special Issue: CRISPR-powered Biosensing (Jan 2021)

Consultant for drug delivery devices and medical diagnostics, Bill & Melinda Gates Foundation (Sep 2017 to present)

1 Kiana Aran Curriculum Vitae. June 2021 NIH postdoctoral fellow, Buck Institute for Research on Aging, Novato, CA, 94945 (Oct 2015 to Jan 2017)

Postdoctoral fellow, Bioengineering Department, Berkeley, Berkeley, CA, 94720 (Oct 2012 to Jan 2017)

Lecturer for a Biomedical Engineering Technology Program, UC Berkeley and Laney College (Aug 2015 to Dec 2016)

Ph.D. Candidate, Biomedical Engineering department, Rutgers University, NJ, 08901 (Sep 2007 to Jan 2012)

Intern (Wise Research Group), School of Applied and Engineering Physics, Cornell University, Ithaca, NY, 14853 (May 2006 to Aug 2006)

Research Assistant, National Oceanic and Atmospheric Administration Cooperative Science Center for Earth System Sciences and Remote Sensing Technologies (NOAA-CREST), Grove School of Engineering, City College of New York, NY 10031

PATENTS  K. Aran, R. Peytavi, B. Goldsmith, A. Kane. “Excitation And Measurement Of Biochemical Interactions” – US - Provisional Application  K. Aran, R. Peytavi. “Systems And Methods For Electronic Detection Of Cleavage And Collateral Activity Of CRISPR-Associated Endonucleases” – US - Non-provisional Application  M. Heltzen, K. Aran, Regis Peytavi. “Systems And Methods For Exosome Capture And Detection” – US – Continuation In Part Application  M. Heltzen, K. Aran, R. Peytavi. “Systems And Methods For Exosome Capture And Detection” (US : 16/459,298)  R. Peytavi, K. Aran. “Devices And Methods For Label-Free Detection Of Analytes” (US 62/883,887)  R. Peytavi, K. Aran, B. Goldsmith, A. Kane. “Enhanced Selection Of Efficient Targeted Genome Manipulating Agents” (US 16/782,795)  R. Peytavi, K. Aran, B. Goldsmith, A. Kane “Enhanced Selection Of Efficient Targeted Genome Manipulating Agents” (WO PCT/US2020/16829)  K. Aran, R. Peytavi. “Systems and Methods for Chip-Assisted CRISPR” (62/801,555) - Provisional  K. Aran, T. Deboer; I. Conboy. “Immobilized RNPs For Sequence-Specific Nucleic Acid Capture And Digital Detection” (US 15/998,353) – Technology was Licensed  K. Aran, Corrine Sadlowskii, Niren Murthy, Irina Conboy. “Graphene-based Biosensor using a Novel Clickable Linker to Detect Molecular Binding Events.” (US BK-2018-037)  K. Aran, J. Perades, N. Murthy, D. Liepmann. “Stimuli Responsive Sensors and Methods of Using the Same (US 62/057,894)  K. Aran, D. Liepmann, N. Murthy. “Active Agent Delivery Devices, and Methods of Using the Same” (WO2016054015A1)- Technology was Licensed

FELLOWSHIPS, AWARDS AND NOMINATIONS

 National Science Foundation (NSF) Career Award  The Presidential Awards for Excellence in Science, Mathematics and Engineering Mentoring Nomination (Jan 2021)  22nd Annual Athena Pinnacle Award Winner (Aug 2020)  Clinical OMICs 10 under 40 Award (April 2020)  Most read Nature Biomedical Engineering Paper Published in 2019 (Jan 2020)  Nature’s “Behind the Paper Top 10” List – 2nd Place (Jan 2020)

2 Kiana Aran Curriculum Vitae. June 2021  The Faculty Diversity in Mentoring Award Nomination (Jan 2020)  The Claremont Colleges Faculty Diversity in Teaching Award Nomination (Jan 2020)  San Diego Venture Group: Coolest Companies of 2019 Award (Jan 2020)  CONNECT by San Diego Venture Group: Most Innovative Product Award in the Life Sciences and Healthtech Category (Dec 2019)  National Institute of Health Fellow: Postdoctoral Training Grant (Feb 2016-Feb 2019)  UC Berkeley postdoc nominee for Rosenman Innovation Award (2015)  UC Berkeley postdoc nominee for the Regeneron Prize for Creative Innovation Award (2015)  Biomedical Engineering Graduate Student Best Manuscript Award (2010) The Sixth International Conference on Pediatric Mechanical Circulatory Support Systems and Pediatric Cardiopulmonary Perfusion, Harvard Medical School, Boston, Massachusetts.  International Conference Presentation Travel Award (2009) The Thirteen International Conferences on Miniaturized Systems for Chemistry and Life Sciences, Jeju, South Korea  Research Fellowship, Johnson & Johnson (2007-2008)  DMJM Harris Scholarship (2006)  Undergraduate Research Fellowship, National Oceanic and Atmospheric Administration (2003-2007)

PUBLICATIONS

2021

1. Hajian, R., DeCastro, J., Parkinson, J., Kane, A., Camelo, A. F. R., Chou, P. P., Yang, J., Wong, N., Hernandez, E. D. O., Goldsmith, B., Conboy, I., Aran, K., Rapid and Electronic Identification and Quantification of Age‐ Specific Circulating Exosomes via Biologically Activated Graphene Transistors. Adv. Biology 2021, 2000594. https://doi.org/10.1002/adbi.202000594

2. S. Balderston, J. Taulbee, E. Celaya, K. Fung, K. Smith, R. Hajian, G. Gasiunas, S. Kutanovas, R. Peytavi, F. Barron, B.R. Goldsmith, P. G. Collins, I. M. Conboy, V. Siksnys, K. Aran, Discrimination of single-point mutations in unamplified genomic DNA via Cas9 immobilized on a graphene field-effect transistor. Nature Biomedical Engineering, 2021, DOI 10.1038/s41551-021-00706-z

3. J. DeCastro, J. Littig, P.P. Chou, J. Mack-Onyeike, A. Srinivasan, M.J. Conboy, I. M. Conboy, & K. Aran. The Microfluidic Toolbox for Analyzing Exosome Biomarkers of Aging. Molecules (Basel, Switzerland), 26(3), 535 (2021). DOI 10.3390/molecules26030535

Accepted:

4. S. Balderston, G. Clouse, J. Ripoll, G. Pratt, G. Gasiunas, J. Bock, E. Bennet, K. Aran. Diversification of the CRISPR Toolbox: Applications of CRISPR-Cas Systems Beyond Genome Editing. The CRISPR Journal (Accepted)

Under Review:

5. P. Amiri, J. DeCastro, J. Litting, H. Lu, C. Liu, I. Conboy, K. Aran. Erythrocytes, a previously unidentified contributor to age-associated blood-brain barrier leakiness. Adv. Science (Under review)

In Preparation:

6. J. DeCastro. A. Srinivasan, T. Han, J. Crawford, K. Aran. CRISPR/Cas Technologies in Aging and Neurological Disorders. (In preparation)

3 Kiana Aran Curriculum Vitae. June 2021 7. M. Mehdipour J. DeCasto, P. Amiri, C. Skinner, C. Kato, E. Watanabe, K. Aran, I.M. Conboy, M.J. Conboy. Peristaltic Pump Design and Mathematical Modeling for Extracorpreal Small Animal Hemapheresis. (In preparation)

8. S. Balderston, G. Clouse, G. Pratt, S. Srinivasan. K. Aran. There’s Still More Juice in the Tank… Alternative Uses to CRISPR Technology. (In preparation)

9. K. Smith, P. Chou, G. Pratt, M. Prinz., L. Le. K. Aran. A new wave of biosensors to circumvent the limitations of conventional COVID-19 tests. (In preparation)

2019

10. D. K. Rai, M. Gurusaran, V. Urban, K. Aran, L. Ma, P. Li, S. Qian, T.N. Narayanan, P.M. Ajayan, D. Liepmann, K. Sekar, M.E. Álvarez-Cao, J.J. Escuder-Rodríguez, M.E Cerdán, M.I. González-Siso, S. Viswanathan, R. Paulmurugan, V. Renugopalakrishnan. Structural determination of Enzyme-Graphene Nanocomposite Sensor Material. Sci Rep 9, 15519 (2019) DOI:10.1038/s41598-019-51882-7

11. R. Haijan, S. Balderston, T. Tran, T. Deboer, J. Etienne, M. Sandhu, N. Wauford, J. Nokes, M. Athaiya, J. Paredes, R. Peytavi, B. Goldsmith, N. Murthy, I.M. Conboy, K. Aran. Detection of unamplified target genes via CRISPR/Cas9 immobilized on a graphene field-effect transistor. 2019, Nature Biomedical Engineering (Front Cover and featured in 30 news articles). DOI 10.1038/s41551-019-037

2018

12. R. Hajian, K. Fung, P. Chou, S. Wang, S. Balderston, K. Aran, Graphene Oxide: Properties and Functionalization Methods. Material Matters, 2018, Vol. 14, Issue 1, 37-45

13. C. M Sadlowski, S. Balderston, M. Sandhu, R. Hajian, C. Liu, T. T Tran, N. Murthy, I. M Conboy, K. Aran, (2018). Graphene-based biosensor for on-chip detection of Bio-orthogonally Labeled Proteins to Identify the Circulating Biomarkers of Aging during Heterochronic Parabiosis. Lab on a Chip (Featured back cover), 2018, 18, 3230 - 3238

2017

14. K. Aran, M. Chooljian, J. Paredes, K. Lee, M. Rafi, N. Murthy, I. Conboy, D. Liepmann, An oral microjet vaccination system elicits antibody production in rabbits, Science Translation Medicine, 2017, Vol. 9, Issue 380, DOI: 10.1126/scitranslmed.aaf6413 (MucoJet Technology)

2015

15. K. Lee, M. Rafi, X. Wang, K. Aran, X. Feng, R. Tang, N. Murthy, In vivo delivery of transcription factors with multifunctional oligonucleotides, Nature Material, 2015, doi:10.1038/nmat4269

16. K. Aran, J. Paredes, M. Rafi, J. Yau, AP. Acharya, M. Zibinskey, D. Liepmann, N. Murthy, Stimuli Responsive Electrodes Detect Oxidative Stress and Liver Injury. Advanced Material (Featured Front Piece), 2015, 8(25), 1432-1436.

17. S.Viswanathan, TN.Narayanan, K. Aran, K. Fink, J. Paredes, PM. Ajayan, D. Liepmann, V. Renu-gopalakrishanan, Graphene–protein field effect biosensors: glucose sensing, 2015, Materials Today, 2015 doi:10.1016/j. mattod.2015.04.003

4 Kiana Aran Curriculum Vitae. June 2021 2014

18. AP. Acharya, P. Sen, K. Aran, AB. Gardner, M. Rafi, D. Dean, N. Murthy, A Turn-Off Fluorescent Substrate for Horseradish Peroxidase Improves the Sensitivity of ELISAs, Journal of Polymer Science, 2014, 53(2) Volume 53, 206–210.

19. D. Liepmann, K. Aran, PM. Ajayan, S. Viswanathan, P. Li, V. Renugopalakrishnan, Graphene Protein Field Effect Biomedical Sensor for Glucose Measurements, MRS Proceedings, 2014, DOI: 10.1557/opl.2015.302

20. K. Aran, J. Paredes, J. Yau. M. Rafi. An Enzyme-free Digital Biosensor for Detection of Reactive Oxygen species. MicroTAS 2014, Miniaturized Systems for Chemistry and Life Sciences.

2013

21. L.A. Sasso, K. Aran, F. Qiu, J. D. Zahn and A. Ündar, Continuous Monitoring of Systemic Inflammation during Cardiopulmonary Bypass Procedure with a Microfluidic Immunoassay Device. Artificial Organs, 2013, 37, 9-17.

2011

22. K. Aran, A. Fok, L.A. Sasso, N. Kamdar, Y. Guan, Q. Sun, A. Undar, and J.D. Zahn, Microfiltration Platform for Continuous Blood Plasma Protein Extraction from Whole Blood during Cardiac Surgery. Lab on a Chip, 2011, 11(17), 2858-2868.

23. K. Aran, M, Morales, L.A. Sasso, J, Lo, J, Zheng, I, Johnson and J. D. Zahn, Microfiltration Device for Continuous, Label-free Bacteria Separation from Whole Blood for Sepsis. MicroTAS, 2011, The Fifteen International Conference on Miniaturized Systems for Chemistry and Life Sciences.

2010

24. K. Aran, A. Fok, Y. Guan, Q. Sun, J. D. Zahn and A. Ündar, Differential Immune Activation During Simulated Cardiopulmonary Bypass Procedure using Freshly Drawn and Week-Old Blood. Artificial Organs, 2010, 34, 1048- 1053.

25. K. Aran, L.A. Sasso, N. Kamdar, and J.D. Zahn. Irreversible, direct bonding of nanoporous polymer membranes to PDMS or glass microdevices. Lab on a Chip, 2010, 10(5), 548-552.

2009

26. K. Aran, A. Fok, Y. Guan, Q. Sun, J. D. Zahn and A. Ündar, A two Compartment Microdialysis Microdevice for Continuous Protein Extraction from Whole blood. MicroTAS 2009, The Thirteenth International Conference on Miniaturized Systems for chemistry and Life Sciences.

REFEREED CONFERENCE PRESENTATIONS AND TALKS (SELECTED)

1. University of California, Irvine’s Fall 2021 Pharmaceutical Sciences Seminar Series, October 2021 (Invited Speaker)

2. Tech Connect World Innovation Conference and Expo, National Harbor, MD, October 2021 (Invited Speaker) Title: CRISPR Powered Transistors: Harnessing Biology as Technology

3. 4th International Conference on CRISPR Technologies, Seattle, WA, October 2021 (Invited Speaker)

5 Kiana Aran Curriculum Vitae. June 2021 4. Horizons in Molecular Biology Symposium Hosted by the International Max Planck Research School for Molecular Biology, September 2021 (Invited Speaker)

5. The Finding Genius Podcast: CRISPR, Research Benefits & The Impact it Makes in Our Lives, June 2021 (Invited Expert)

6. University of California, Riverside, PERSIST Program, May 2021 (Invited Talk)

7. Advanced Material Future Preparedness Taskforce’s MATTER 2021 Forum, April 2021 (Invited Panelist)

8. New York University Spring Seminar, April 2021 (Invited Speaker) Title: The story behind CRISPR-chip, the first CRISPR-powered Transistor, from research bench to commercialization

9. Scismic and Loyola Marymount University’s Women in Life Sciences, March 2021 (Invited Panelist)

10. The Scientist, Webinar, March 2021 (Invited Panel Speaker) Title: From Tubes to Transistors to Biology Gated Transistors

11. Biosensors for Pandemics 2021, February 2021 (Invited Speaker) Title: Next Generation Graphene Transistors for Biological Threat

12. Women in Science and Engineering (WISE) National Conference, January 2021 (Invited Panel Speaker)

13. MNM, December 2020 (Invited Speaker) Title: Biology-gated Transistors for Multiomics Applications

14. Materials Research Society (MRS) Spring/Fall Meeting & Exhibit, December 2020 (Invited Speaker) Title: CRISPR-Powered Transistors—Harnessing Biology as Technology

15. University of California, Berkeley, November 2020 (Invited Guest Lecturer) Title: Using Biology-gated Transistors for Multiomics Applications

16. World CRISPR Day, Virtual, October 2020 (Invited Speaker) Title: An Automated Integrated Multiple Assay Technology utilizing CRISPR-based Transistors for CRISPR Quality Control Applications

17. Women in Biotech Lithuania, Lithuanian Association, October 2020 (Keynote Speaker)

18. Defense Threat Reduction Agency, Virtual, October 2020 (Invited Speaker) Title: Using Biology-gated Transistors for Multiomics Applications

19. CRISPR Medicine News, July 2020 (Virtual Talk) Title: The CRISPR-Chip can optimize your Cas, diagnose COVID19 and change our world

20. Synthego CRISPR Office Hours, May 2020, (Invited Speaker) Title: Fighting COVID-19 with CRISPR-Chip-Powered Diagnostics

21. Molecular Medicine Tri-Conference, San Francisco, CA, March 2020 (Session Chair) Title: CRISPR-Powered: CRISPR-Powered Transistors for DNA Biosensing

22. W.M. Keck Science Department (Claremont McKenna, Pitzer, and Scripps Colleges) Keck Seminar Series, 2020 (Invited Speaker) Title: CRISPR-Powered: CRISPR-Powered Transistors for DNA Biosensing

23. PMWC, Santa Clara, CA, January 2020 (Invited Panelist)

6 Kiana Aran Curriculum Vitae. June 2021 Title: How CRISPR Revolutionizes Genomic Medicine

24. California Institute of Technology, Pasadena, CA 2019 (Invited Talk) Title: CRISPR-Powered Transistors for DNA Biosensing

25. Point of Care Diagnostics, Global Health and Biosensors Conference 2019 (Invited Speaker) Title: CRISPR-Powered Transistors for DNA Biosensing

26. CRISPR Technologies Conference, Wurzburg Germany, 2019 (Invited Speaker) Title: CRISPR-Powered Transistors for DNA Biosensing

27. AGBT Precision Health Conference, San Diego, 2019 (Speaker and Poster Presentation) Title: Genome Sensor: The CRISP-Chip Technology Allowing you to Google Genomes

28. Genome Engineering Summit Hosted by Synthego, 2019 CRISPR-Chip: A CRISPR-Powered Graphene Based DNA Search Engine

29. Keck Graduate Institute Women’s Leadership Summit, 2019 (Invited Speaker)

30. LabRoots Molecular Diagnostics Virtual Conference, 2019 Title: CRISPR-Chip: Detection of Unamplified Target Genes via CRISPR/CAS9 immobilized on Graphene Biosensors

31. Nature Conference on In Vitro Diagnostics 2019 (Invited Speaker)

32. BioE Seminar Rising Stars UC Berkeley Bioengineering (Invited Speaker)

33. IEEE EMBS, 2018 (Invited Talk) Title: Graphene-based biosensors for research and diagnostic applications

34. International Drug Discovery Science and Technology (IDDST), 2018 (Invited Talk) Title: Recent Advances and Challenges in Non-invasive Oral Drug Delivery Platforms

35. Drug Delivery West, 2018 (Invited Talk), Title: Challenges in oral delivery of biologics using drug-device combinations

36. Materials Research Society (MRS), Boston, 2017 (Invited Talk and Invited Chair, Biosensors) Title: Applications of Graphene in Medicine

37. Seminar Series, 2017 (Invited Talk) Title: Point of Care Biosensors for Diagnostic Applications

38. University of California, Riverside, Department of Bioengineering, 2017 (Invited Talk) Title: Medical Devices for Oral Drug Delivery and Clinical Diagnostics

39. IDTechEX, Printed Sensors, 2016, (Invited Chair)

40. Berkeley Sensor and Actuator Center, (BSAC), 2016, (Podium Presentation) Title: Graphene-based Biosensors: From Functionalization to Sensing

41. University of Navarra, Spain: Center for Applied Medical Research (CIMA), 2016 (Invited Talk) Title: MEMS-based Devices for Oral Drug Delivery

42. University of Navarra, Spain: The School of Engineering (TECNUN), 2016 (Invited Talk) Title: Design and Construction of a Biosensor for Monitoring Oxidative Stress

7 Kiana Aran Curriculum Vitae. June 2021 43. Robert Bosch LLC, Research & Technology Center (Bosch, Palo Alto), 2015 (Invited Talk) Title: Early detection of drug induced liver toxicity utilizing a point of care biosensor

44. Biomedical Engineering Society Annual Meeting. San Antonio, (BMES), 2014 (Podium Presentation) Title: A Point of Care Digital Biosensor for Early Detection of Lipid Hydroperoxides for Early Prevention of Atherosclerosis

45. Biomedical Engineering Society Annual Meeting. San Antonio, (BMES), 2014 (Podium Presentation) Title: 3D Printed Pills for Oral Delivery of Proteins and Peptides.

46. The Eighteen International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS), 2014 (Poster Presentation) Title: Digital Biosensors based on Biologically Responsive Polymers

47. Velocity pharmaceutical development Corporation (Velocity, South San Francisco), 2014, (Invited Talk) Title: A new MEMs based platform for oral delivery of protein-based drugs

48. Berkeley Sensor and Actuator Center, (BSAC), 2014, (Podium Presentation) Title: A digital biosensor for early detection of circulating reactive oxygen metabolites

49. University of California, Irvine, Department of Pharmaceutical Sciences, 2012 (Invited Talk) Title: Blood separation in microfluidic devices

50. The 15th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS), 2014 (Poster Presentation) Title: Microfiltration Device for Continuous, Label-free Bacteria Separation from Whole Blood for Sepsis

51. The Seventh International Conference on Pediatric Mechanical Circulatory Support Systems and Pediatric Cardiopulmonary Perfusion, 2011 (Invited Talk) Title: Microfiltration Device for Continuous Intrinsic Separation of Blood Components during Mechanical Circulatory Support

52. The Sixth International Conference on Pediatric Mechanical Circulatory Support Systems and Pediatric Cardiopulmonary Perfusion, 2010 (Podium Presentation) Title: Differential Immune Activation During Simulated Cardiopulmonary Bypass Procedure Using Freshly Drawn and Week-Old Blood

53. The Thirteenth International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS), 2009 (Poster Presentation) Title: A two Compartment Microdialysis Microdevice for Continuous Protein Extraction from Whole blood

54. The Fourth Annual NOAA-CREST Symposium, (NOAA) 2006, (Poster Presentation). Title: Correlation between Fluorescence Height and Chlorophyll a Concatenation based on the Field Measurements and Satellite Data for Chesapeake Bay

CURRENT RESEARCH INTEREST:

1. Medical devices for diagnostics and drug delivery 2. Graphene-based biosensors for diagnostics, therapeutics and biomarker discovery. 3. Utilization of novel polymers and chemical linkers within semiconductor-based devices for biosensing applications. 4. Assembly, encapsulation and interconnection of semiconductor-based devices for biosensing applications. 5. Design and fabrication of miniaturized systems for sample enrichment for biosensing applications

8 Kiana Aran Curriculum Vitae. June 2021 6. Design and fabrication of noninvasive drug delivery systems for noninvasive delivery of biologics.

MENTORSHIP AND MANAGMENT EXPERIENCE

 2017-present PI/Mentor/Supervisor to students from Keck Graduate Institute, Harvey Mudd, Scripps, Claremont McKenna, Pitzer, and Pomona Colleges. Advisor for Team Masters Projects (TMP) in collaboration with corporate partners. Director for High School Summer STEM program at Keck Graduate Institute. PI to summer program stduents in Medical Device Development Bootcamp, Summer Undergraduate Research Experience, and High School Summer STEM Program. Supervisor to students for Independent Research Credits. Courses: Medical Devices, Advanced Medical Devices: Drug Delivery, Advanced Medical Devices: Biosensors

 2015-2016 Lecturer/Supervisor at UC Berkeley and Laney College for Biomedical Engineering Technology Program Designed and taught Introduction to Biomedical Engineering courses and labs. Managed all the project supplies for the lab. Supervising students in multiple labs: Conboy and Liepmann labs.

 2012-2016 Mentor/Supervisor at UC Berkeley. Designed projects, trained, mentored, and supervised 6 undergraduate and 3 PhD candidates and junior postdoctoral fellows. Coordinated meetings and managed the research supplies for the lab. Designed and refined the animal protocols for all the projects in the lab. Managed all the lab instruments and research supplies.

 2007-2012. Mentor/Tutor and Teaching Assistant at the School of Biomedical Engineering, Rutgers University. Trained and supervised 3 undergraduates and 1 master students, teaching assistant for Biomechanics and BioMEMs courses.

PROFESSIONAL MEMBERSHIPS:

 IEEE  Berkeley Sensor & Actuator Center  Biomedical Engineering Society  International Society for Pediatric Mechanical Cardiopulmonary Support (Founding Member)  ACS, American Chemical Society  SWE, Society of Women Engineer  EMBS, Engineering in Medicine & Biology Society

RESEARCH FUNDING:

Completed:  National Institute of Health-T32 Aran (PI) 01/01/2015-01/012017

Current:  National Science Foundation (NSF) Career Award 01/15/2021-01/31/2026  University of California, Berkeley/NIH-RO1-Aran (PI) 04/01/2018-03/31/2022 New Generation Blood Exchange Devices for Enhancing Tissue Regeneration and Health  University of California, Berkeley Sub Award (PI) 10/01/2017-10/01/2021 (Renewable) Developing microfluidic platforms for continuous blood exchange between old and young mice  Progenity, Inc (PI) 09/01/17-09/01/21 (Renewable) Developing Gastrointestinal Absorption Maps for Biological Therapeutics  Keck Graduate Institute (PI) (On Going) Institutional Start-up Funds

9 Kiana Aran Curriculum Vitae. June 2021  Cardea Bio Inc. (PI) 09/01/19-09/01/21 (Renewable) Developing Capturing Mechanisms for Graphene-based Biosensors  Nanosens Innovations Inc. (PI) 09/01/19-09/01/21 (Renewable) Developing Capturing Mechanisms for Graphene-based Biosensors

Grants Submitted:  NIH R01 CRISPR-powered transistors for amplification-free detection of viral RNA for differential diagnostics  NIH R01 CRISPR-based transistors for high throughput multiplexed monitoring of CRISPR-based editing efficiency for Sickle cells disease  DARPA DIGET BAA In collaboration with multiple institutions  NIH R01 An electronic biosensor for facile evaluation of gRNA designs in CRISPR/Cas9 -based sickle cell disease therapies  NIH R01 Understanding the age-specific effects of erythrocytes on the brain  NIH R01 Graphene-based biosensor for On-chip detection of Bio-orthogonally Labeled Proteins to Identify the Circulating Biomarkers of Aging during Heterochronic Parabiosis.  DOD CDMRP Label-free digital biosensor for rapid identification of bio-orthogonally tagged proteins

10 Kiana Aran Curriculum Vitae. June 2021