Neurobiology of & Disorders: Genetic and MRI Advances Monday 9th July 2018, Leolin Price Lecture Theatre (one day symposium)

Session Time Topic Speaker Chair Prof. Angela Morgan 9:15 – 9:45am Diagnosis and treatment Childhood apraxia of Murdoch Children’s Research Institute speech/ Dr. Frederique Liegeois 9:45 – 10:15am MRI correlates Dr. Frederique Liegeois developmental verbal University College London dyspraxia Prof. Faraneh Vargha-Khadem 10:15 – 10:45am FOXP2 and early development University College London 10:45 – 11:15am Coffee break Using state-of-the-art genomics to study Prof. Simon Fisher 11:15 – 12:00pm developmental speech disorders. Max Planck Institute of Psycholinguistics Child Prof. Angela Morgan Prof. Kate Watkins 12.00 – 12:30pm MRI correlates of Oxford University Epilepsy- My child stopped speaking: genetic disorders Prof. Ingrid Scheffer 12:30 – 1:00pm A/Prof. Michael Hildebrand syndromes encompassing epilepsy and aphasia University of Melbourne 1:00 – 2:00pm Lunch break Prof. James Law 2:00 –2:30pm Diagnosis and treatment Newcastle University Childhood language Dr. Dianne Newbury 2:30 – 3:15pm Genetics of child language disorder Prof. Melanie Bahlo disorder Oxford-Brookes University Neural correlates of developmental language Dr. Saloni Krishnan 3:15 – 3:45pm disorders Oxford University Gene discovery in the speech and language A/Prof. Michael Hildebrand Gene discovery for 3:45 – 4:15pm clinic University of Melbourne speech & language Prof. Melanie Bahlo Prof. Ingrid Scheffer disorders – implications Bioinformatics in the speech and language 4:15 – 4:45pm Walter and Eliza Hall Institute of Medical for the clinic clinic Research Finding a cause for child speech and language disorders - what benefit for children and their Panel discussion 4:45 – 5:15pm families? Prof. Torsten Baldeweg Questions from the audience 5:15pm Drinks reception

Neurobiology of Speech & Language Disorders: Genetic and MRI Advances Monday 9th July 2018, Leolin Price Lecture Theatre (one day symposium)

KEYNOTE SPEAKERS Prof. Simon E. Fisher is a director of the Max Planck Institute for Psycholinguistics and Professor of Language and Genetics at the Donders Institute for Brain, Cognition and Behaviour, in Nijmegen, the Netherlands. Simon's research focuses on molecular mechanisms involved in human speech and language abilities. His work has an interdisciplinary perspective, integrating data from genetics/genomics, psychology, neuroscience, developmental biology and evolutionary anthropology.

Dr. Dianne Newbury is a molecular geneticist who studies genetic contributions to childhood neurodevelopmental disorders. Her investigations specifically focus around developmental language disorders and their relationship to other neurodevelopmental difficulties, such as dyslexia. Dianne has a lab at Oxford Brookes University and her research is currently funded by the Leverhulme Trust and the ESRC.

INVITED SPEAKERS Prof. Faraneh Vargha-Khadem is head of the Cognitive Neuroscience and Neuropsychiatry Section at the UCL Great Ormond Street Institute of Child Health, one of the world’s leading institutions in paediatric research. She heads UCL Centre for Developmental Cognitive Neuroscience (CDCN). She pioneered research into cognitive and MRI profiles of individuals with FOXP2 gene anomalies. Her work in the field of paediatrc , such as developmental amnesia, is also internationally recognised.

Prof. Kate Watkins is a Professor of Cognitive Neuroscience and Head of the Speech and Brain Research Group in the Department of Experimental Psychology at the . Her research interests are in the brain processes underlying speech and language and brain development.

Prof. James Law is Professor of Speech and Language Science at Newcastle University in the UK. He has been in receipt of research grant funding of in the order of £5.0m and has published over 200 peer reviewed and other publications. He was one of the Principal Investigators of the Department for Education funded Better Communication Research Programme and is now one of the Chief Investigators on the Australian NHMRC Centre for Excellence in Child Language. Dr. Saloni Krishnan is a Postdoctoral Research Fellow in the Speech and Brain Group at the University of Oxford. She is interested in how brain circuits for speech/language change over childhood and how they may be altered in developmental speech and language disorders.

Neurobiology of Speech & Language Disorders: Genetic and MRI Advances Monday 9th July 2018, Leolin Price Lecture Theatre (one day symposium)

CRE SPEECH AND LANGUAGE TEAM SPEAKERS Prof. Angela Morgan is a speech pathologist, NHMRC Practitioner Fellow and leads the Centre of Research Excellence in Speech and Language and the Speech and Language group at the Murdoch Children’s Research Institute in Melbourne, Australia. Her expertise is in speech and language phenotyping for genetic conditions.

Dr. Frederique Liegeois is a cognitive neuroscientist in the Cognitive Neuroscience and Neuropsychiatry Section at the UCL Great Ormond Street Institute of Child Health, one of the world’s leading institutions in paediatric research. Frederique is internationally renowned for her work on the neural bases of inherited and acquired communication disorders.

Prof. Ingrid Scheffer is a Laureate Professor in Paediatric Neurology, University of Melbourne and Senior Principal Research Fellow at the Florey Institute of Neuroscience. Ingrid is a paediatric neurologist and epileptologist and her collaborative research group was the first to discover a gene for epilepsy and subsequently, many of the genes known to be implicated. She was awarded the L’Oréal-UNESCO Women in Science Laureate for the Asia-Pacific region in 2012 and the Australian Prime Minister’s Prize for Science in 2014.

A/Prof. Michael Hildebrand is a molecular geneticist with a well-established track record in applying genetic and functional approaches to elucidate novel pathways involved in human disease. Michael’s focus for the past decade has been discovery and characterization of novel deafness, epilepsy and speech disorder genes.

Prof. Melanie Bahlo is a statistical geneticist/bioinformatician who develops and applies methods to discover the underlying genetic causes of diseases such as speech disorders. Her lab is based at the Walter and Eliza Hall Institute of Medical Research in Melbourne, Australia.