SLAMF6 Antibody Cat. No.: 30-592

SLAMF6 Antibody

Specifications

HOST SPECIES: Rabbit

SPECIES REACTIVITY: Human

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region IMMUNOGEN: of human SLAMF6.

TESTED APPLICATIONS: ELISA, WB

SLAMF6 antibody can be used for detection of SLAMF6 by ELISA at 1:62500. SLAMF6 APPLICATIONS: antibody can be used for detection of SLAMF6 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

POSITIVE CONTROL: 1) Cat. No. 1309 - Human Placenta Lysate

PREDICTED MOLECULAR 34 kDa WEIGHT:

Properties

PURIFICATION: Antibody is purified by peptide affinity chromatography method.

CLONALITY: Polyclonal

CONJUGATE: Unconjugated

PHYSICAL STATE: Liquid

October 1, 2021 1 https://www.prosci-inc.com/slamf6-antibody-30-592.html Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% BUFFER: sucrose.

CONCENTRATION: batch dependent

For short periods of storage (days) store at 4˚C. For longer periods of storage, store STORAGE CONDITIONS: SLAMF6 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.

Additional Info

OFFICIAL SYMBOL: SLAMF6

ALTERNATE NAMES: SLAMF6, KALI, KALIb, Ly108, MGC104953, NTB-A, NTBA, SF2000, CD352

ACCESSION NO.: NP_443163

PROTEIN GI NO.: 16418407

GENE ID: 114836

USER NOTE: Optimal dilutions for each application to be determined by the researcher.

Background and References

SLAMF6 is a type I transmembrane , belonging to the CD2 subfamily of the immunoglobulin superfamily. SLAMF6 is expressed on Natural killer (NK), T, and B lymphocytes. It undergoes tyrosine phosphorylation and associates with the Src homology 2 domain-containing protein (SH2D1A) as well as with SH2 domain-containing phosphatases (SHPs). It may function as a coreceptor in the process of NK cell activation. It can also mediate inhibitory signals in NK cells from X-linked lymphoproliferative patients. The protein encoded by this is a type I transmembrane protein, belonging BACKGROUND: to the CD2 subfamily of the immunoglobulin superfamily. This encoded protein is expressed on Natural killer (NK), T, and B lymphocytes. It undergoes tyrosine phosphorylation and associates with the Src homology 2 domain-containing protein (SH2D1A) as well as with SH2 domain-containing phosphatases (SHPs). It may function as a coreceptor in the process of NK cell activation. It can also mediate inhibitory signals in NK cells from X-linked lymphoproliferative patients. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.

REFERENCES: 1) Claus, M., (er) Front. Biosci. 13, 956-965 (2008).

ANTIBODIES FOR RESEARCH USE ONLY.

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