Nocturnal Enuresis Or Bedwetting
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Supporting Children with Autism with Bedwetting Difficulties
Supporting Children with Autism with Bedwetting Difficulties (Primary Nocturnal Enuresis) Bedwetting is described as involuntary wetting during sleep, and is a common occurrence in childhood. Ten per cent of 7 year olds are affected by bedwetting. Boys are affected more than girls, and there is often a family history. Bedwetting often improves with age. There is a higher incidence of bedwetting in children with Autism Spectrum Disorders (ASD). Bedwetting can occur as a result of one or more of the following reasons: 1. Bladder control has not yet matured 2. Sleeping deeply and not waking in response to a full bladder 3. Producing a lot of urine at night due to hormonal reasons 4. Overactive bladder (by day and by night) Recommendations Avoid any punishment for bedwetting. Anxiety or significant socialisation difficulties can affect bedwetting. Focus on these first before addressing bedwetting. Children with ASD often have sleep difficulties. Any approaches to help bedwetting should not affect sleep. Strategies Use social stories and visual schedules to support your child. Examples include; a schedule of their bedtime routine that may include two trips to the toilet (see below), and social stories about what to do if their bed is wet when they wake during the night or in the morning. Set realistic and appropriate targets, and reward your child for achieving them. Rewarding a dry night may be unachievable initially and may result in disappointment for your child. An example of an achievable target may be; putting a used pull up in the bin, or helping to change the sheets. Empty bladder at night-time as part of bedtime routine. -
Traditional Medicine and Ethnomedical Research
International Conference on TRADITIONAL MEDICINE AND ETHNOMEDICAL RESEARCH OCTOBER 24-25, 2019 ToKYO, JAPAN Theme: Healthy Life in Natures Lap Radisson Hotel Narita 286-0221 Chiba Tomisato-shi Nakaei 650-35 Tokyo, Japan @ICTM2019 TraditionalMedicine_EthnoMedicine_2019 ICTM https://traditional-medicine-conferences.magnusgroup.org/ EXHIBITOR 2019 ICTM 2019 BOOK OF ABSTRACTS International Conference on TRADITIONAL MEDICINE AND EtHNOMEDICAL RESEARCH Theme: Healthy Life in Natures Lap October 24-25, 2019 Tokyo, Japan INDEX Contents Pages Welcome Message 8 Keynote Speakers 10 About the Host 11 About Exhibitor 12 Keynote Session (Day 1) 13 Speaker Session (Day 1) 19 Keynote Session (Day 2) 37 Speaker Session ( Day 2) 43 Poster Presentations 66 Attendees Mailing List 74 ICTM 2019 Abuzar Ansari Amrita Sharma Annette Booiman Arturo Huerta-López Baohong Jiang Ewha Womens University Amrita’s Ayuryogavidya, a Mensendieckmoves, Comunidad Biocultural, A.C., Shanghai Institute of Materia Mokdong Hospital, Korea centre of excellence for well- Netherlands México Medica, China ness and holistic health, India Barend van Heerden Bernd-Michael Löffler Chanin Sillapachaiyaporn Charles Shang Chen Che-Yi Indian Board of Alternative Institute for Mitochondrial Chulalongkorn University, University Of Texas MD Ander- Taipei Medical University, Medicine, South Africa Medicine, Germany Thailand son Cancer Center, USA Taiwan Chihiro Sugita Dominique de Rocca Serra Fai Chan Fossion Jean G. R. Padmasiri Kyushu University of Health University of Corsica Deli Aroma LLC Group Investigation of dys-Au- University of the Visual and and Welfare, Japan France USA tonomy (GidA), Belgium Performing Arts, Sri Lanka Geoffrey W Abbott Hiroyoshi Tahata Irmgard Rose Parys James Teng Jia-Ming Chen University of California, Japanese Rolfing Association, Community Practice Dres. -
Current Current
CP_0406_Cases.final 3/17/06 2:57 PM Page 67 Current p SYCHIATRY CASES THAT TEST YOUR SKILLS Chronic enuresis has destroyed 12-year-old Jimmy’s emotional and social functioning. The challenge: restore his self-esteem by finding out why can’t he stop wetting his bed. The boy who longed for a ‘dry spell’ Tanvir Singh, MD Kristi Williams, MD Fellow, child® Dowdenpsychiatry ResidencyHealth training Media director, psychiatry Medical University of Ohio, Toledo CopyrightFor personal use only HISTORY ‘I CAN’T FACE MYSELF’ during regular checkups and refer to a psychia- immy, age 12, is referred to us by his pediatri- trist only if the child has an emotional problem J cian, who is concerned about his “frequent secondary to enuresis or a comorbid psychiatric nighttime accidents.” His parents report that he wets disorder. his bed 5 to 6 times weekly and has never stayed con- Once identified, enuresis requires a thorough sistently dry for more than a few days. assessment—including its emotional conse- The accidents occur only at night, his parents quences, which for Jimmy are significant. In its say. Numerous interventions have failed, including practice parameter for treating enuresis, the restricting fluids after dinner and awakening the boy American Academy of Child and Adolescent overnight to make him go to the bathroom. Psychiatry (AACAP)1 suggests that you: Jimmy, a sixth-grader, wonders if he will ever Take an extensive developmental and family stop wetting his bed. He refuses to go to summer history. Find out if the child was toilet trained and camp or stay overnight at a friend’s house, fearful started walking, talking, or running at an appro- that other kids will make fun of him after an acci- priate age. -
Hair Pulling Disorder)
THE IMPACT OF PULLING STYLES ON FAMILY FUNCTIONING AMONG ADOLESCENTS WITH TRICHOTILLOMANIA (HAIR PULLING DISORDER) A thesis submitted To Kent State University in partial Fulfillment of the requirements for the Degree of Master of Arts by Yolanda E. Murphy May, 2016 © Copyright All rights reserved Except for previously published materials Thesis written by Yolanda E. Murphy B.S., Howard University, 2013 M.A., Kent State University, 2016 Approved by Christopher Flessner, Ph.D. , Advisor Manfred van Dulmen, Ph.D., Acting Chair, Department of Psychological Sciences James L. Blank, Ph.D. , Interim Dean, College of Arts and Sciences TABLE OF CONTENTS LIST OF TABLES……………………………………………………………………………..iv INTRODUCTION……………………………………………………………………………..1 METHOD………………………………………………………………………………………6 RESULTS……………………………………………………………………………………...15 DISCUSSION…………………………………………………………………………….……20 REFERENCES…………………………………………………………………………….…..26 iii LIST OF TABLES Table 1. Demographic Characteristics of Adolescent HPD and Control Samples……………....7 Table 2. Demographic Characteristics of Parents (Mothers, Fathers) Present at Initial Intake Assessment………………………………………………….………………………….8 Table 3. Regression Summary for CRPBI Controls vs. Cases Analyses.…...………………......16 Table 4. Regression Summary for FES Controls vs. Cases Analyses.…...……………………...17 Table 5. Regression Summary for ATMCRC Pulling Style Analyses.….…………....…….…...18 Table 6. Characteristics of HPD Sample.…………………………………....…………………..18 iv Introduction Trichotillomania (hair pulling disorder, HPD) is characterized by the recurrent pulling out of one’s hair, resulting in hair loss. Although largely understudied in the pediatric population, HPD research suggests a substantial presence of this disorder amongst youths. The precise number of youth affected is unknown, however past research in adult populations indicates approximately 3.4% of adults to be affected by HPD, with a large portion of individuals exhibiting an adolescent onset (i.e. mean age of 13; Bruce, Barwick, & Wright, 2005; Christenson, Pyle, & Mitchell, 1991). -
42711 IPEG Programmaboekje
19 th Biennial Conference 19th Biennial Conference October 26th – 30th 2016 October 26 Nijmegen, the Netherlands th – 30 th 2016 Nijmegen, the Netherlands 2016 Nijmegen, 42711 IPEG programmaboekje omslag.indd 1 06-10-16 17:52 The “International Pharmaco-EEG Society, Association for Electrophysiological Brain Research in Preclinical and Clinical Pharmacology and Related Fields” (IPEG) is a non-profit organization, established in 1980 and composed of scientists and researchers actively involved in electrophysiological brain research in preclinical and clinical pharmacology, neurotoxicology and related areas of interest. my.thesis nl for the design of your Thesis & to show your Thesis 42711 IPEG programmaboekje omslag.indd 2 06-10-16 17:52 IPEG 2016 in Nijmegen | 1 Welcome to Nijmegen, dear attendants of the 19th IPEG meeting. Nijmegen, a 2000 year old city; Nijmegen, a Roman and a medieval city; Nijmegen, the home town of the first catholic university funded by the Faithfull to improve education of a suppressed part of the Netherlands; Nijmegen, the city that heavily suffered in WWII; Nijmegen, the home town of the Donders Institute. Nijmegen, as we hope and trust, your home town for the upcoming IPEG meeting. As you all know, electrophysiological brain research has a long tradition going back as far as 1875 when the first report on the animal electroencephalogram (EEG) was published by Caton. The often forgotten Polish physiologist Adolf Beck was also a EEG pioneer many years before Hans Berger’s initial reports. Beck recorded electrical potentials in several brain areas evoked by peripheral sensory stimuli. Using this technique, Beck localised various centres in the brain of several animal species and described desynchronization in electrical brain potentials. -
Functional Connectivity Changes in Cerebral Small
Schulz et al. BMC Medicine (2021) 19:103 https://doi.org/10.1186/s12916-021-01962-1 RESEARCH ARTICLE Open Access Functional connectivity changes in cerebral small vessel disease - a systematic review of the resting-state MRI literature Maximilian Schulz1, Caroline Malherbe1,2, Bastian Cheng1, Götz Thomalla1 and Eckhard Schlemm1* Abstract Background: Cerebral small vessel disease (CSVD) is a common neurological disease present in the ageing population that is associated with an increased risk of dementia and stroke. Damage to white matter tracts compromises the substrate for interneuronal connectivity. Analysing resting-state functional magnetic resonance imaging (fMRI) can reveal dysfunctional patterns of brain connectivity and contribute to explaining the pathophysiology of clinical phenotypes in CSVD. Materials and methods: This systematic review provides an overview of methods and results of recent resting- state functional MRI studies in patients with CSVD. Following the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) protocol, a systematic search of the literature was performed. Results: Of 493 studies that were screened, 44 reports were identified that investigated resting-state fMRI connectivity in the context of cerebral small vessel disease. The risk of bias and heterogeneity of results were moderate to high. Patterns associated with CSVD included disturbed connectivity within and between intrinsic brain networks, in particular the default mode, dorsal attention, frontoparietal control, and salience networks; decoupling of neuronal activity along an anterior–posterior axis; and increases in functional connectivity in the early stage of the disease. Conclusion: The recent literature provides further evidence for a functional disconnection model of cognitive impairment in CSVD. -
19Th Biennial IPEG Meeting Nijmegen, the Netherlands
Neuropsychiatric Electrophysiology 2016, 2(Suppl 1):8 DOI 10.1186/s40810-016-0021-4 MEETINGABSTRACTS Open Access 19th biennial IPEG Meeting Nijmegen, The Netherlands. 26-30 October 2016 Published: 29 November 2016 Training course measures. This will be illustrated by means of pertinent examples. These include elucidating the mechanisms of stimulant action re- A1 mediating deficient impulse control and the role of the cannabinoid Thalamocortical sleep oscillations system in human working memory, as well as drug effects on Igor Timofeev1,2 sensory gating and specific aspects of visual-spatial attention. Other 1Department of Psychiatry and Neuroscience, Université Laval, Québec, examples concern the added sensitivity of EEG and ERP measures, Canada; 2Centre de recherche de l’Institut universitaire en santé mentale relative to that of performance measures, in detecting effects of alco- de Québec (CRIUSMQ), Université Laval, Québec, Canada hol, and more generally in monitoring and predicting vigilance and Neuropsychiatric Electrophysiology 2016, 2(Suppl 1):A1 the ability to detect external signals in the immediate future. Rela- tions between brain signals and cognitive competences are revealed In waking and sleeping states, thalamocortical system generates a by either comparing different individuals, or moment-to-moment variety of oscillations ranging from 0.1 Hz to hundreds of Hz. Most of fluctuations within individuals, or differences in state (e.g., drug- them are present during NREM sleep, but slower activities prevail in induced) within individuals. this state of vigilance. Thalamocortical network is organized in a loop in which thalamocortical cells excite reticular thalamic and neocor- tical cells, reticular thalamic cells inhibit thalamocortical cells and A3 corticothalamic cells excite thalamocortical and reticular thalamic EEG and ERP as key techniques for functional brain alterations cells. -
Rehabilitation of Executive Dysfunction in Multiple Sclerosis: Cognitive, Behavioural and Neurophysiological Effects of Goal Management Training
Rehabilitation of Executive Dysfunction in Multiple Sclerosis: Cognitive, Behavioural and Neurophysiological Effects of Goal Management Training by Nadine Marie Richard A thesis submitted in conformity with the requirements for the degree of Doctor of Philosophy Department of Psychology University of Toronto © Copyright by Nadine Marie Richard 2013 Rehabilitation of Executive Dysfunction in Multiple Sclerosis: Cognitive, Behavioural and Neurophysiological Effects of Goal Management Training Nadine Marie Richard Doctor of Philosophy Department of Psychology University of Toronto 2013 Abstract Multiple sclerosis (MS) is a chronic, progressive central nervous system disease characterized by distributed white matter injury. Particularly prevalent in Canada, MS is a leading cause of disability with extended personal and societal costs given its early onset (on average between 20- 40 years of age). Deficits in executive functioning are common and detrimental to employment, daily functioning and quality of life, however their precise nature remains underspecified. Two studies were undertaken to: (1) describe the executive processes affected in MS, including neurophysiological correlates, and (2) explore, in a double-blind randomized controlled trial, patients’ response to an intervention for improving behavioural self-regulation. Study 1 described significant functional limitations and impairments in processing speed and executive control of attention, memory and working memory in MS patients, both relative to neurologically healthy controls and as a monotonic function of disease severity. Mean amplitudes for event- related potentials (ERPs) including the P3 and the error-related negativity and positivity (ERN, Pe) were linked to behavioural markers of attention control and performance monitoring. ERP amplitudes and ERP-behavioural associations appeared sensitive to the presence and severity of executive dysfunction related to disease progression. -
Secondary Enuresis & Body Dysmorphic Disorder in A
Psychiatria Danubina, 2010; Vol. 22, Suppl. 1, pp 53–55 Conference paper © Medicinska naklada - Zagreb, Croatia SECONDARY ENURESIS & BODY DYSMORPHIC DISORDER IN A CAUCASIAN MALE WITH CATATONIC SCHIZOPHRENIA: A case report Nuruz Zaman, Milind Karale & Mark Agius South Essex Partnership University Foundation NHS Trust, UK SUMMARY We describe a patient with Schizophrenia and secondary enuresis. The enuresis settled with resolution of his psychotic symptoms but later remerged after starting Clozapine. We explore the mechanisms of incontinence in Schizophrenia and those due to Clozapine. This case highlights the need to inquire about incontinence in patients with schizophrenia prior to prescribing clozapine. Key words: schizophrenia – enuresis – clozapine – incontinence - body dysmorphic disorder * * * * * Introduction Clozapine. This case highlights the need to inquire about incontinence in patients with schizophrenia prior Urinary incontinence in patients with schizophrenia to prescribing clozapine. can present with daytime urinary leakage, urge incontinence and bed wetting. The association between Case Report bedwetting and schizophrenia has been noted since the pre neuroleptic era when Kraeplin reported a group of Mr AP is a 21 year old man who was referred to an schizophrenic patients with resistant incontinence. child and adolescent outpatient clinic at the age of 17 Various mechanisms have been postulated for this with a six month history of not coping with training and association. The ventricular enlargement (hydrocepha- educational tasks. He had low mood, poor self esteem, lus), selective neuronal loss with gliosis, and dopamine occasional aggressive outbursts and certain compulsion dysregulation in schizophrenia may indicate a like repeatedly checking doors, windows and mirrors. neurological basis to the incontinence. These anatomical He walked with his hand over his nose and perceived lesions might interrupt the pathways of bladder control people to be laughing at his nose. -
Aripiprazole-Induced Diurnal and Nocturnal Enuresis in Down's Syndrome
ARIPIPRAZOLE-INDUCED DIURNAL AND NOCTURNAL ENURESIS IN DOWN’S SYNDROME STEFANO MARINI (1) 1 Il Cireneo Foundation for Autism Spectrum Disorder, Vasto, Italy. INTRODUCTION Aripiprazole is an atypical antipsychotic with unique pharmacological profile: partial agonist for dopamine D2 and serotonin 5-HT1A and antagonist for 5-HT2A receptors. Moreover, it also exhibits affinity for dopamine D4, serotonin 5-HT2C, and 5-HT7, alpha 1 adrenergic and histamine H1 receptors [1]. Compared with other atypical antipsychotics, aripiprazole is known to have fewer adverse effects, particularly QTc prolongation, weight gain, and dysregulation of glucose and lipid metabolism, sedation, and prolactin elevation. However, common side effects are represented by headache, tremor, akathisia, nausea, vomiting, constipation, somnolence, dyspepsia, and insomnia. In the clinical practice, aripiprazole is prescribed for psychosis, bipolar disorder, adjunctive treatment of major depressive disorder, Tourette’s syndrome, irritability, and behavioral problems associated with autism spectrum disorder. Past literature highlighted clozapine, risperidone, olanzapine, and quetiapine-induced enuresis. Aripiprazole-induced enuresis has been reported as a very rare adverse effect, but contrasting data has been found in different types of patients. In children, two studies reported an aripiprazole-induced enuresis [2,3], and two studies in adults used aripiprazole to treat enuresis caused by other treatments [4,5]. CASE PRESENTATION 20-years old female drug-naive outpatient affected by Down’s syndrome and mental retardation presented auditory hallucinations, irritability, anger bursts, self-harm and aggression towards others and an increase of stereotyped behaviors. In author’s knowledge, no psychopharmacology guidelines have been published yet for the treatment of psychiatric symptoms in patients affected by Down’s Syndrome. -
An Fmri Study Xiangyu Zheng1,7, Jiawei Sun2,7, Yating Lv3,4, Mengxing Wang5, Xiaoxia Du6, Xize Jia3,4* & Jun Ma1*
www.nature.com/scientificreports OPEN Frequency‑specifc alterations of the resting‑state BOLD signals in nocturnal enuresis: an fMRI Study Xiangyu Zheng1,7, Jiawei Sun2,7, Yating Lv3,4, Mengxing Wang5, Xiaoxia Du6, Xize Jia3,4* & Jun Ma1* Resting state functional magnetic resonance imaging studies of nocturnal enuresis have focused primarily on regional metrics in the blood oxygen level dependent (BOLD) signal ranging from 0.01 to 0.08 Hz. However, it remains unclear how local metrics show in sub‑frequency band. 129 children with nocturnal enuresis (NE) and 37 healthy controls were included in this study. The patients were diagnosed by the pediatricians in Shanghai Children’s Medical Center afliated to Shanghai Jiao Tong University School of Medicine, according to the criteria from International Children’s Continence Society (ICCS). Questionnaires were used to evaluate the symptoms of enuresis and completed by the participants. In this study, fALFF, ReHo and PerAF were calculated within fve diferent frequency bands: typical band (0.01–0.08 Hz), slow‑5 (0.01–0.027 Hz), slow‑4 (0.027–0.073 Hz), slow‑3 (0.073– 0.198 Hz), and slow‑2 (0.198–0.25 Hz). In the typical band, ReHo increased in the left insula and the right thalamus, while fALFF decreased in the right insula in children with NE. Besides, PerAF was increased in the right middle temporal gyrus in these children. The results regarding ReHo, fALFF and PerAF in the typical band was similar to those in slow‑5 band, respectively. A correlation was found between the PerAF value of the right middle temporal gyrus and scores of the urinary intention‑ related wakefulness. -
Treatment Options for Clozapine-Induced Enuresis: a Review of Clinical Effectiveness
TITLE: Treatment Options for Clozapine-Induced Enuresis: A Review of Clinical Effectiveness DATE: 27 September 2010 CONTEXT AND POLICY ISSUES: Clozapine is an atypical antipsychotic indicated in the management of treatment-resistant schizophrenia.1 Clozapine binds dopamine receptors as well as exerting potent anticholinergic, adrenolytic, antihistaminic, and antiserotoninergic activity.1 It has been shown to be efficacious in treating both the positive (e.g., hallucinations) and negative symptoms (e.g., social withdrawal) associated with schizophrenia. Patients treated with clozapine may experience adverse effects ranging in severity from relatively benign to serious and potentially life-threatening conditions such as seizures and agranulocytosis.1,2 One potential adverse effect is enuresis, or an inability to control urination, which can cause emotional stress and poor compliance among the affected patients.3 The true prevalence of clozapine-induced enuresis has yet to be determined as published estimates range from 0.23% to 44%.4,5 The reasons for this lack of consistency is are unclear and may be related to differences in dosage,6 ethnicity,7 and treatment setting.3 The mechanism for clozapine-induced enuresis has not been fully elucidated; however, a leading hypothesis involves blockade of the α-adrenergic receptors resulting in a decrease in internal bladder sphincter tone.7 A number of treatments are available for the management of enuresis including desmopressin,8 tricyclic antidepressants,9 anticholinergics,10 and alarms.11 However, there is currently no universally accepted approach to addressing clozapine-induced enuresis.2,6 This report reviews the safety and effectiveness of the various treatment strategies for clozapine- induced enuresis.