NeoBiotechnologies, Inc. 2 Union Square Union City, CA 94587 Tel: 510-376-5603 Email: [email protected] , [email protected] Website: www.NeoBiotechnologies.com

ASRGL1 (Asparaginase Like 1) Mouse Monoclonal Antibody [Clone CRASH/1289]

Catalog No Format Size Price (USD)

80150-MSM1-P0 Purified Ab with BSA and Azide at 200ug/ml 20 ug 199.00

80150-MSM1-P1 Purified Ab with BSA and Azide at 200ug/ml 100 ug 459.00

80150-MSM1-P1ABX Purified Ab WITHOUT BSA and Azide at 1.0mg/ml 100 ug 459.00

Human Entrez ID 80150 Immunogen Recombinant human ASRGL1 fragment

Human SwissProt Q7L266 Host / Ig Isotype Mouse / IgG1, kappa

Human Unigene 535326 Mol. Weight of Antigen 17-25kDa

Human Gene Symbol ASRGL1 Cellular Localization Cytoplasmic and Nuclear

Human 11q12.3 Species Reactivity Human. Location Positive Control HeLa cells. , Endometrium, Uterus or . Synonyms ALP1; ASGL1; Asparaginase like 1; ASRGL1; beta-aspartyl-peptidase; CRASH; isoaspartyl dipeptidase; isoaspartyl peptidase/L-asparaginase; L asparaginase; L asparagine amidohydrolase

Formalin-fixed, paraffin-embedded human Fallopian Tube stained with ASRGL1 Mouse Monoclonal Antibody (CRASH/1289).

Specificity & Comments Supplied As ASRGL1 (Asparaginase-like protein 1), also known as CRASH, is a 308 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. amino acid protein belonging to the Ntn-hydrolase family. Asparaginases Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available utilize asparagine as a substrate to produce aspartic acid and ammonia. WITHOUT BSA & azide at 1.0mg/ml. ASRGL1 has been identified as a autoantigenic protein that is present in the mid-piece of sperm after obstruction of the male reproductive tract. ASRGL1 Storage and Stability is expressed highly in testis, but is also expressed in brain, kidney and gastrointestinal tissues. High levels of ASRGL1 have also been identified in Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 ovarian, uterine and mammary tumors in comparison with normal tissues of to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS the same origin. required.

Known Applications & Suggested Dilutions Limitations This antibody is available for research use only and is not approved for use in diagnosis.

Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT)(Staining of formalin-fixed tissues is enhanced by heating tissue Warranty sections in 10mM Tris with 1mM EDTA, pH 9.0 for 45 min at 95°C There are no warranties, expressed or implied, which extend beyond this followed by cooling at RT for 20 minutes)Optimal dilution for a specific description. Company is not liable for any personal injury or economic application should be determined. loss resulting from this product.

Key References

1. Evtimova, V. et al. 2004. Int. J. Oncol. 24: 33-41.

NBT01289