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UKOSS Newsletter 52 UK Obstetric Surveillance System 52 NEWSLETTER 52 - January 2018 52 Anaphylaxis Study Published The results of the UKOSS anaphylaxis study have recently been published in BJOG (McCall SJ, et al. The incidence, characteristics, management and outcomes of anaphylaxis in pregnancy: a population-based descriptive study. BJOG2018; https://doi.org/10.1111/1471-0528.15041.) • The aim of this study was to describe the incidence, causative agents, management and associated outcomes of anaphylaxis in association with pregnancy. • 37 women with anaphylaxis associated with pregnancy were identified between October 2012 and September 2015, giving an estimated incidence of 1.6 (95% CI: 1.1–2.2) per 100 000 maternities. • Four cases occurred in women with known penicillin allergies: two received co-amoxiclav and two cephalosporins. • Twelve women had anaphylaxis following prophylactic use of antibiotics at the time of a caesarean delivery. Prophylactic use of antibiotics for Group B streptococcal infection accounted for anaphylaxis in one woman. • Two women died (5%), 14 (38%) women were admitted to intensive care and seven women (19%) had one or more additional severe maternal morbidities. • No infants died; however, in those infants whose mother had anaphylaxis before delivery (n=18) there were seven (41%) neonatal intensive care unit admissions, three preterm births and one baby was cooled for neonatal encephalopathy. • This study highlights the seriousness of the outcomes of this condition for the mother. The low incidence is reassuring given the large proportion of the pregnant population that receive prophylactic antibiotics during delivery. WHO GLOSS Study Update Thank you to all reporters who have reported cases and returned data collection forms for the WHO GLOSS study. 480 cases reported so far and still counting. If you haven’t returned your reports, please return them as soon as possible as the WHO want all data by the end of February. THIS MONTH This month: - SHIP and EpiduralChanges Haematoma to the UKOSS have team recently ended The newsletter goes digital - Meet a member of the UKOSS team Thanks to the following hospitals who have returned reports for September, October and November 2017: Aberdeen Maternity Hospital Queen’s Hospital - Romford, Essex North Manchester General Hospital Airedale General Hospital Queen’s Medical Centre Northampton General Hospital Altnagelvin Area Hospital Rosie Maternity Hospital Northwick Park Hospital Antrim Hospital Royal Albert Edward Infirmary Pilgrim Hospital Arrowe Park Hospital Royal Berkshire Hospital Pinderfields General Hospital Barnsley Hospital NHS Foundation Trust Royal Bolton Hospital Prince Charles Hospital Bedford Hospital Royal Cornwall Hospital Princess Royal Hospital - Telford Birmingham Women’s Hospital Royal Devon & Exeter Hospital Princess Royal Maternity Hospital Borders General Hospital Royal Free Hospital Queen Alexandra Hospital Bradford Royal Infirmary Royal Free London NHS Foundation Trust Royal Alexandra Hospital Bronglais Hospital Royal Glamorgan Hospital Royal Sussex County Hospital Broomfield Hospital Royal Gwent Hospital South West Acute Hospital Caithness General Hospital Royal Hampshire County Hospital Southmead Hospital Calderdale Royal Hospital Royal Jubilee Maternity Service St John’s Hospital Causeway Hospital Royal London Hospital St Mary’s Hospital - Manchester Chesterfield & North Derbyshire Royal Hospital Royal Oldham Hospital St Mary’s Hospital - Newport City Hospitals Sunderland NHS Trust Royal Surrey County Hospital St Michael’s Hospital Colchester General Hospital Royal Victoria Infirmary The Great Western Hospitals NHS Foundation Countess of Chester Hospital Russells Hall Hospital Trust Craigavon Area Hospital Scarborough Hospital University College Hospital Croydon University Hospital Scunthorpe General Hospital University Hospital Lewisham Cumberland Infirmary Simpson Centre for Reproductive Health Wishaw General Hospital Daisy Hill Hospital Singleton Hospital Worthing Hospital Darent Valley Hospital Southend University Hospital NHS FT Wythenshawe Hospital Darlington Memorial Hospital St Helier Hospital East Surrey Hospital Diana Princess of Wales Hospital St James’s University Hospital Kettering General Hospital Doncaster Royal Infirmary St Mary’s Hospital - London Lincoln County Hospital Dorset County Hospital St Peter’s Hospital Liverpool Women’s Hospital Dr Gray’s Hospital St Richard’s Hospital Manor Hospital - Walsall Dumfries & Galloway Royal Infirmary Stoke Mandeville Hospital North Middlesex University Hospital Epsom General Hospital Stoke Mandeville Hospital Princess Elizabeth Hospital Forth Valley Royal Hospital The Hillingdon Hospitals NHS Foundation Trust Queen Charlotte’s and Chelsea Hospital Frimley Park Hospital The Portland Hospital Queen Elizabeth Hospital - Gateshead Furness General Hospital The Tunbridge Wells Hospital Raigmore Hospital George Eliot Hospital Torbay Hospital Royal Lancaster Infirmary Good Hope Hospital Ulster Hospital Royal United Hospital Guy’s and St Thomas’ Hospital University Hospital of Coventry & Warwickshire Stepping Hill Hospital Harrogate District Hospital University Hospital of North Tees Tameside General Hospital Hinchingbrooke Hospital NHS Trust University Hospital of Wales The Jessop Wing Hull Royal Infirmary Victoria Hospital - Blackpool University Hospital of North Midlands - James Cook University Hospital Victoria Hospital - Kirkcaldy Stoke-on-Trent James Paget University Hospitals Trust Warrington and Halton Hospitals NHS FT Worcestershire Royal Hospital John Radcliffe Hospital Warwick Hospital Lancashire Women and Newborn Centre King’s College Hospital West Cumberland Hospital Macclesfield District General Hospital King’s Mill Hospital West Middlesex University Hospital Queen’s Hospital - Burton-on-Trent Kingston Hospital West Suffolk Hospital Rotherham District General Hospital Lancashire Teaching Hospitals West Wales General Hospital Salisbury District Hospital Leeds General Infirmary Western Isles Hospital South Tyneside NHS Foundation Trust Leicester Royal Infirmary Wexham Park Hospital Southern General Hospital Leighton Hospital Whipps Cross University Trust Hospital Southport & Ormskirk Hospital NHS Trust Lister Hospital Whiston Hospital St George’s Hospital Medway Maritime Hospital Whittington Hospital University Hospital of North Durham Milton Keynes Hospital NHS Foundation Trust William Harvey Hospital - East Kent Watford General Hospital Musgrove Park Hospital Wrexham Maelor Hospital Nevill Hall Hospital Yeovil Women’s Hospital New Cross Hospital York Hospital Newham General Hospital Ysbyty Gwynedd District General Hospital Ninewells Hospital & Medical School Ayrshire Maternity Unit Nobles Hospital Basildon Hospital Norfolk & Norwich University Hospital Bassetlaw District General Hospital North Devon District Hospital Birmingham City Hospital North Hampshire Hospital Birmingham Heartlands Hospital Northumbria Specialist Emergency Hospital Chelsea & Westminster Hospital Nottingham City Hospital Derby Hospitals NHS Foundation Trust Peterborough City Hospital Derriford Hospital Poole Hospital East Sussex Healthcare NHS Trust Princess Alexandra Hospital Glan Clwyd District General Hospital Princess Anne Hospital Gloucestershire Royal Hospital Princess of Wales Hospital Hereford County Hospital Princess Royal Hospital - Haywards Heath Homerton University Hospital Princess Royal University Hospital Ipswich Hospital Queen Elizabeth Hospital - Kings Lynn Jersey General Hospital Queen Elizabeth Hospital - Woolwich, London Leicester General Hospital Queen Elizabeth the Queen Mother Hospital Luton & Dunstable Hospital Returned all three reports. Returned two reports. Returned one report. No reports returned. Follow us @NPEU_UKOSS Recently Finished Studies: Epidural Haematoma and Abscess and SHIP The Epidural Haematoma and Abscess study and the SHIP study have now ended. Please can all UKOSS reporters check that they have reported all cases. Please ensure that all outstanding data collection forms are returned as soon as possible. If you have any queries, please do not hesitate to contact the UKOSS team at [email protected] Breast Cancer Study The breast cancer study is now in the final stages of data collection. Please ensure all outstanding case reports and forms are returned as soon as possible. Case report summary for current studies up until the end of September 2017 Actual number of Data collection forms Expected number of Disorder reported cases returned (%) confirmed cases Amniotic Fluid Embolism 262 250 (95) 155 Cirrhosis in Pregnancy 12 5 (42) 30 Epidural Haematoma or Abscess 26 23 (88) 8 High Neuraxial Block 20 7(35) 33 Low Maternal Plasma Fibrinogen 16 5(31) 30 Seasonal Influenza 130 88 (68) 59 SHiP 26 23 (88) 30 WHO GLOSS 480 72(15) N/A Chocolates this month go to Susanna Al-Samarrai from King’s Mill Hospital for prompt completion and return of data collection forms and Janet Cresswell from Chesterfield & Royal Derbyshire Hospital for prompt return of GLOSS data collections forms. This month: Read more online Changes to the UKOSS team To read this on your phone or to access our complete archive: Open the BARCODE READER APP* on yourThe phone newsletter and scan goes the digitalcode here *Search your app store for ‘qrcode’ Melanie O’Connor, UKOSS Programme Manager, interviews Jennie Duffin who recently joined the UKOSS team MO’C: What is your current role within the UKOSS team? JD: I am the Deputy Programme Manager for UKOSS. I work closely with Melanie (the Programme Manager)
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