COURSE DESCRIPTION VIRTUAL CONFERENCE Challenges in is a 3-day CME program sponsored by the Department of Medicine of the Icahn School of Medicine at Mount Sinai. The goal of this course is Featuring live interactive Q & A with faculty experts to offer providers of primary care services the newest pharmacologic and technologic breakthroughs, updates in clinical therapeutic guidelines, and highlights of recent advances in the practice of Internal Medicine. The intended audience for this course is Internists, Family Practitioners, Nurse Practitioners, Physician Assistants and their trainees.

Primary care is growing increasingly more difficult due to the complexity of the patient’s CHALLENGES medical condition coupled with advances in clinical management. This course is geared to help providers practice evidence-based medicine from today’s scientific literature. The goal from this format is to help the clinician to better manage their patients using IN INTERNAL MEDICINE the latest evidence-based practices.

All of the discussants incorporate recent medical literature in their talks. Importantly, many of the lectures chosen are from the current year’s Divisional and Departmental Grand Rounds. Wednesday, Thursday, Friday n  n New Approaches to n Oncology June 9-11, 2021 n Renal Development Common Problems n Endocrine Disease n Orthopaedics n New Therapeutic Live Virtual Conference Modalities 12 pm - 6 pm EST / 9 am - 3 pm PST WHO SHOULD ATTEND: EDUCATIONAL OBJECTIVES: n Primary Care At the conclusion of this activity, participants will be able to: Course Directors Physicians – Summarize recent updates, clinical studies, new Yousaf Ali, MD, FACR pharmacologic options and guidelines that impact John A. Andrilli, MD, FACP n Nurse Practitioners practice in general medicine and subspecialties. – Describe updates and advances in the treatment Christina M. Cruz, MD n Physician Assistants of Cancer, Hypertension and Renal Disease, Liver Douglas T. Dieterich, MD Disease, and Cardiology. David C. Thomas, MD, MHPE n Fellows & Residents – Summarize helpful pearls in the areas of Bias, Travel Medicine, Asthma, Anemia, Colorectal n Specialist Physicians Cancer and approach to lowering low-density Provided by lipoprotein cholesterol (LDL-C). Samuel Bronfman Department of Medicine Icahn School of Medicine at Mount Sinai – Discuss updates and advances in the treatment Mount Sinai Health System of Canceclinical reasoning and interpretation of tests for common problems in Endocrinology, Rheumatology, and Dermatology.

Online Registration: https://mssm.cloud-cme.com/cim GENERAL INFORMATION MOUNT SINAI HEALTH SYSTEM

COURSE DIRECTORS/PLANNING COMMITTEE Yousaf Ali, MD, FACR Douglas T. Dieterich, MD Associate Professor of Medicine Professor of Medicine Chief, Division of Rheumatology Director, Institute for Liver Medicine Mount Sinai West and Mount Sinai Morningside Mount Sinai Health System CHALLENGES John A. Andrilli, MD, FACP David C. Thomas, MD, MHPE Associate Professor of Medicine Professor of Medicine, Medical Education and IN INTERNAL MEDICINE Internal Medicine Residency Program Director Rehabilitation Medicine Mount Sinai West and Mount Sinai Morningside Vice Chair for Education Christina M. Cruz, MD Associate Dean for CME Assistant Professor of Medicine Mount Sinai Health System Internal Medicine Residency Live Virtual Conference Associate Program Director for Ambulatory Care Mount Sinai Beth Israel

ACCREDITATION FACULTY DISCLOSURE FACULTY The Icahn School of Medicine at Mount Sinai It is the policy of Icahn School of Medicine at Mount is accredited by the Accreditation Council for Sinai to ensure objectivity, balance, independence, Daniel S. Caplivski, MD James Marion, MD Continuing Medical Education to provide continuing trans­parency, and scientific rigor in all CME-sponsored Associate Professor of Medicine, Infectious Diseases Professor of Medicine, medical education for physicians. educational activities. All faculty participating in the Michelle S. Cespedes, MD, MS Bryan C. Markinson, DPM planning or implementation of a sponsored activity Associate Professor of Medicine, Infectious Diseases Assistant Professor of Orthopaedics and Pathology The Icahn School of Medicine at Mount Sinai designates are expected to disclose to the audience any relevant this internet live course for a maximum of 16.0 AMA Caroline Cromwell, MD Bahar Moghaddam, MD financial relationships and to assist in resolving any PRA Category 1 Credit(s)™. Physicians should claim Assistant Professor of Medicine, Hematology and Medical Assistant Professor of Medicine, Rheumatology conflict of interest that may arise from the relationship. only the credit commensurate Oncology Presenters must also make a meaningful disclosure Barbara Murphy, MD with the extent of their Alexis C. Colvin, MD Murray M. Rosenberg Professor of Medicine to the audience of their discussions of unlabeled or participation in the activity. Associate Professor of Orthopedics System Chair, Department of Medicine unapproved drugs or devices. This information will be Dean for Clinical Integration and Population Health Successful completion of this CME activity, which available as part of the course materials. Amreen Dinani, MD includes participation in the evaluation component, Assistant Professor of Medicine, Liver Diseases Satish Nagula, MD Associate Professor of Medicine, Gastroenterology enables the participant to earn up to 16.0 MOC points CANCELLATION POLICY Andrew S. Dunn, MD, MPH and Medical Knowledge MOC points in the American All refund and cancellation requests must be emailed Professor of Medicine, Hospital Medicine Mary O’Sullivan, MD Board of Internal Medicine’s (ABIM) Maintenance of to the CME office at [email protected] by June 1, 2021. Assistant Professor of Medicine, Pulmonary, Karim El Hachem, MD Critical Care and Sleep Medicine Certification (MOC) program. Cancellations after this date are not eligible for a Assistant Professor of Medicine, refund. An administrative fee of $50 will be deducted It is the CME activity provider’s responsibility to Bradford Parsons, MD from your refund. No refunds will be issued for Samira Farouk, MD Professor of Orthopedics submit participant completion information to ACCME Assistant Professor of Medicine, Nephrology for the purpose of granting ABIM MOC credit. registration fees that are equal to or less than $50. Charles A. Powell, MD Icilma V. Fergus, MD Professor of Medicine, Pulmonary, Critical Care and In order to obtain MOC credit, participants will be CONFERENCE INFORMATION Associate Professor of Medicine, Cardiology Sleep Medicine asked to complete a post-activity assessment online. Please contact the office of CME 212.731.7950 or Peter Goulden, MD As part of the assessment, learners will submit a email [email protected]. Register online at Sylvia Reyes, MD, MBS Senior Faculty of Medicine, Endocrinology, Diabetes and Assistant Professor of Surgery, Surgical Oncology reflective statement on intention to change practice https://mssm.cloud-cme.com/cim Bone Disease based on the knowledge gained from participation. Linda Rogers, MD Steven H. Itzkowitz, MD Learners will also be required to provide ABIM number Syllabus Associate Professor of Medicine, Pulmonary, Professor of Medicine and Oncological Sciences Critical Care and Sleep Medicine and month/date of birth (mm/dd). Registered participants may visit: Florian Krammer, PhD Joshua Safer, MD This information will be transmitted by the accredited Your computer: Professor of Microbiology provider to the ACCME Program and Activity https://mssm.cloud-cme.com “Sign In”, select Senior Faculty of Medicine, Endocrinology, Diabetes and Bone Disease Reporting System (PARS) by December 1, 2021. “My CME” then select “Syllabus” Anuradha Lala-Trindade, MD Assistant Professor of Medical, Cardiology Reshmi Srinath, MD VERIFICATION OF ATTENDANCE Your smartphone: Download & open the Assistant Professor of Medical, Population Health Science Assistant Professor of Medicine, Endocrinology, All professionals will be able to download, verification CloudCME App (first time user, if prompted, and Policy Diabetes and Bone Disease of attendance. use “MSSM” as the organization code) Mark G. Lebwohl, MD Joseph M. Truglio, MD, MPH SPECIAL NEEDS “Sign In”, select “Syllabus” Professor of Dermatology Assistant Professor of Medicine, Pediatrics and Medical Dean for Clinical Therapeutics Education Icahn School of Medicine at Mount Sinai is in full Registration compliance with provisions of the Americans Rosanne M. Leipzig, MD, PhD Includes electronic syllabus Che-Kai Tsao, MD with Disabilities Act (ADA) and is accessible for Professor of Geriatrics and Palliative Medicine Associate Professor of Medicine, Hematology and individuals with special needs. If you require special Online Registration Sean T. Liu, MD, PhD Medical Oncology accommodations contact The Page and William Black https://mssm.cloud-cme.com/cim Assistant Professor of Medicine, Infectious Diseases, Hospital Mariam Zakhary, DO Post-Graduate School at 212-731-7950. Medicine, Microbiology Assistant Professor of Rehabilitation Medicine WEDNESDAY, JUNE 9, 2021 THURSDAY, JUNE 10, 2021 FRIDAY, JUNE 11, 2021

11:55 am - 12:00 pm EST ORTHOPAEDICS FOR PCPs 11:55 am - 12:00 pm EST 2:45-3:15 11:55 am - 12:00 pm EST 2:45-3:15 Introduction and Welcome Introduction and Welcome Updates in HIV 2021 Introduction and Welcome Update on Breast Cancer 3:00-3:30 Screening Barbara Murphy, MD The Foot as a Mirror of Yousaf Ali, MD, FACR Michelle S. Cespedes, MD, MS Yousaf Ali, MD, FACR Murray M. Rosenberg Professor of Medicine Sylvia Reyes, MD, MBS Systemic Disease John A. Andrilli, MD, FACP 3:15-3:45 John A. Andrilli, MD, FACP System Chair, Department of Medicine Christina M. Cruz, MD Christina M. Cruz, MD Dean for Clinical Integration and Bryan C. Markinson, DPM Asthma Update 3:15-3:45 Population Health Douglas T. Dieterich, MD Douglas T. Dieterich, MD CRC Screening Update 3:30-4:00 Linda Rogers, MD Icahn School of Medicine at Mount Sinai David C. Thomas, MD, MHPE David C. Thomas, MD, MHPE Steven H. Itzkowitz, MD Common Upper Extremity 3:45-4:00 Orthopedics for the PCP Break 3:45-4:15 HELPFUL PEARLS CLINICAL REASONING FOR CARDIOLOGY Bradford O. Parsons, MD Update in Medical COMMON PROBLEMS Therapy for IBD 4:00-4:30 12:00-12:30 4:00-4:30 12:15 - 12:45 Anemia for the PCP James Marion, MD CHF: Management Back Pain Transgender Health 12:00-12:30 Caroline Cromwell, MD Anuradha Lala-Trindade, MD Mariam Zakhary, DO Joshua Safer, MD Interpretation of Normal & 4:15-4:30 Abnormal Rheum Tests Break 4:30-4:45 12:30-1:00 4:30-5:00 12:45 - 1:15 New Therapies for HBV/HCV Yousaf Ali, MD, FACR Peri-operative Management Break Anti-Racism in Medicine 4:30-5:00 of Anticoagulation Joseph M. Truglio, MD, MPH Douglas T. Dieterich, MD 12:30-1:00 Upper GI Disease for the Andrew S. Dunn, MD, MPH 5:00-5:30 Advances in Rheumatology Primary Care Physician NEW APPROACHES TO 1:00-1:30 for the PCP Travel Medicine for the NASH Satish Nagula, MD 1:15-1:45 YOUR PATIENTS Bahar Moghaddam, MD Women and Heart Disease Internist Amreen Dinani, MD Update 4:45-5:15 Daniel S. Caplivski, MD IMPROVING YOUR Common Hip and Knee Issues CHALLENGING SCENARIOS MANAGEMENT OF THE Icilma V. Fergus, MD for the PCP 1:30-2:00 IN ONCOLOGY PATIENT WITH ENDOCRINE 1:45-2:00 pm EST COVID-19 Vaccine Therapies Alexis C. Colvin, MD DISEASE Break Florian Krammer, PhD 1:00-1:30 5:15-5:45 Smoking Cessation 2:00-2:15 5:00-5:30 Geriatric Syndrome for the Mary O’Sullivan, MD Internist Break Updates in Medical RENAL DEVELOPMENTS Management of Obesity Rosanne M. Leipzig, MD, PhD 1:30-2:00 2:00-2:30 2:15-2:45 Lung Cancer Update Reshmi Srinath, MD HTN: New Developments COVID-19 Update Charles A. Powell, MD 5:30-6:00 Karim El Hachem, MD DERMATOLOGY Sean T. Liu, MD, PhD 2:00-2:15 Diabetes: Management 2:30-3:00 5:45-6:15 Break Peter Goulden, MD Hot Topics in Chronic Kidney The Dermatology Top 10 6:00 Disease Management Mark G. Lebwohl, MD 2:15-2:45 Samra Farouk, MD Prostate Cancer Update Closing Remarks/ Che-Kai Tsao, MD Adjournment

Agenda Subject to Change AGENDA