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Integrin Signaling Card

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Integrin Signaling Card Integrin Signaling in Shear Stress-induced Endothelial Cell Dysfunction Pathway PECAM-1 Src NADPH oxidase VE-cadherin NF-κB Rac Flk1 PI 3-kinase PAK PECAM-1 Src NADPH JNK Integrin α2β1 oxidase activation ? VE-cadherin ICAM-1 Rac IKK MKK4 VCAM-1 Flk1 PI 3-kinase Pro-inflammatory gene expression α5β1, αvβ3 PAK Permeability Basement Membrane ATHEROGENESIS (e.g. Collagen IV and Laminin) Transitional Matrix (e.g. Fibronectin and Fibrinogen) Discover more at abcam.com/integrin Produced in collaboration with Dr. A. Wayne Orr, LSU Health Sciences Center. Integrin Signaling in Shear Stress-induced Endothelial Cell Dysfunction Pathway Related antibodies Product highlights Antibody Clonality Applications Host Species Reactivity Product Code Integrin alpha 5 (ab6131) Clonality Applications Collagen IV P IHC-P, IHC-FoFr, IP, WB, ELISA, IHC-Fr Rb Hu, Ms, Rat, Cow ab6586 M Flow Cyt, ICC/IF, IP Fibrinogen P IHC-P, ELISA, ICC/IF, FuncS Rb Hu, Ms, Rb ab34269 Host Species cross reactivity Ms Hu Fibronectin M AP, ICC/IF, IHC-Fr, IHC-P, RIA, WB Ms Hu, Ms, Rat, Chk, Cow, Dog, Pig ab6328 FLk1 / VEGF Receptor 2 P IP, Flow Cyt, IHC-P, ICC/IF, IHC-Fr Rb Hu, Ms, Rat, Cow, Dog ab2349 ICAM1 M ELISA, Flow Cyt, IP, WB Ms Hu, Rat, Cow ab2213 IKK alpha + IKK beta P IHC - P, ELISA Rb Hu, Ms ab62481 Integrin beta 1 (ab52971) Integrin alpha 2 M IP, Flow Cyt, IHC-P, IHC-Fr Ms Hu ab10800 Clonality Applications P Flow Cyt, ICC/IF, IHC-Fr, IHC-P, IHC-P, WB Integrin alpha 2 + beta 1 M Flow Cyt, IP, WB, ELISA, ICC/IF, IHC-Fr Ms Hu ab30483 Host Species cross reactivity Integrin alpha 5 M Flow Cyt, ICC/IF, IP Ms Hu ab6131 Rb Hu, Ms, Rat Integrin alpha 5 + beta 1 M Flow Cyt, IP, Inhib, WB, IHC-Fr Rat Ms ab77981 Integrin alpha v M ELISA, Flow Cyt, ICC/IF, IHC-P, IP Ms Hu ab16821 Integrin alpha v + beta 3 M BL, IP, IHC-Fr Ms Hu ab78289 PAK1 (ab40795) Integrin beta 1 M Flow Cyt, ICC/IF, IHC-Fr, IHC-P, IHC-P, WB Rb Hu, Ms, Rat ab52971 Clonality Applications Integrin beta 3 M Flow Cyt, ICC/IF, IHC-Fr, IHC-P, IP, Inhib, WB Ms Hu ab7167 M ICC/IF, IHC-P, IP, WB JNK1+JNK2 (phospho T183+Y185) P IHC-P, WB, ICC/IF, IHC-Fr Rb Hu, Ms, Predicted: Many ab4821 Host Species cross reactivity JNK1+JNK2+JNK3 P WB, ELISA Rb Hu, Ms, Rat ab59227 Rb Hu, Ms, Rat Laminin P Dot, ICC/IF, IHC-FoFr, IHC-Fr, IHC-P, IP Rb Hu, Ms, Mamm, Amph, Dog, Pig, Rept ab11575 MKK4 / MEK4 (phospho S80) P IHC-P, WB, ELISA Rb Hu, Ms, Rat ab39403 NFkB P ChIP, EMSA, ICC/IF, IHC-Fr, IHC-P, IP, WB Rb Hu, Ms, Rat ab7970 Laminin (ab11575) PAK1 M ICC/IF, IHC-P, IP, WB Rb Hu, Ms, Rat ab40795 Clonality Applications PAK1+PAK2+PAK3 P IHC - P, ELISA Rb Hu, Ms, Rat ab59248 P Dot, ICC/IF, IHC-FoFr, IHC-Fr, IHC-P, IP Host Species cross reactivity PECAM1 / CD31 M IP, WB, ICC/IF Ms Hu, Ms, Rat ab24590 Rb Hu, Ms, Dog, Pig, Xl PECAM1 / CD31 (APC) M BL, Flow Cyt, IP, IHC-Fr Rat Ms ab25563 PI 3 Kinase p85 alpha M Flow Cyt, ICC/IF, IHC-P, IP, WB Rb Hu, Rat ab40755 Rac1 P IHC-P, WB, ICC/IF Rb Hu, Ms ab78139 Rac2 P IHC-P, WB, ELISA Gt Hu ab2244 Fibronectin (ab6328) Clonality Applications Src P IHC-P, WB, ELISA, ICC/IF Rb Hu, Ms, Rat ab47405 M AP, ICC/IF, IHC-Fr, IHC-P, RIA, WB Src (phospho Y529) M IP, WB, ICC/IF, Dot Rb Hu, Ms, Rat ab32078 080-09/09-PW Host Species cross reactivity VCAM1 (FITC) M Flow Cyt, ICC/IF, FuncS, IP Rat Ms ab24853 Ms Hu, Ms, Rat, Chk, Cow, Dog, Pig Flow Cyt, IHC-P, IHC-Fr, IP, Neut, WB, P, VE cadherin M ICC/IF Ms Hu, Ms ab7047 Discover more at abcam.com/integrin Copyright © 2013 Abcam. All Rights Reserved..
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