June 26, 2012 u vol. 109 u no. 26 u 10125–10606

Cover image: Pictured is the giant nudibranch, Dendronotus iris, with brightly colored spines and gills. This soft-bodied sea slug feeds on the burrowing anemone and sequesters toxins from its prey, which are then used as a defense. These animals are also capable of swimming to escape from predators. James M. Newcomb et al. review the evolution of swimming behaviors in shell-less mollusks at the behavioral and neuronal levels, as discussed at the Arthur M. Sackler Colloquium, “In the Light of Evolution VI: Brain and Behavior.” See the article by Newcomb et al. on pages 10669–10676 in supplement 1. Image courtesy of Charuni A. Gunaratne. From the Cover

10669 Evolution of swimming behaviors 10138 Fate of Indus Valley Civilization 10150 Profiling microbial colonies 10156 10158 Molecular basis of malaria 10160g 10293 Anthropoids in Africa

Contents QNAS 10127 QnAs with Peter M. Kareiva Prashant Nair THIS WEEK IN PNAS COMMENTARIES 10125 In This Issue 10128 A massively spectacular view of the chemical lives of microbes Matthew F. Traxler and Roberto Kolter LETTERS (ONLINE ONLY) See companion article on pages E1743 and 10150 10130 Molecular basis of severe malaria E1676 Sex may influence the mediating effect of honesty Kirk W. Deitsch and Chetan E. Chitnis in the relationship between serotonin and reaction See companion articles on pages E1772 and 10156; to unfairness E1782 and 10158; and E1791 and 10160 Zhibing Yang, Danmin Miao, Xufeng Liu, 10132 Evidence for an Asian origin of stem anthropoids and Xia Zhu Richard F. Kay E1677 Reply to Yang et al.: Gender is not a confounding See companion article on page 10293 factor of our result 10134 Extortion and cooperation in the Prisoner’s Dilemma Hidehiko Takahashi, Harumasa Takano, Takashi Ideno, Alexander J. Stewart and Joshua B. Plotkin Yuki Tamari, Kazuhisa Takemura, and Tetsuya Suhara See companion article on page 10409

E1678 Reply to van Hoorn: Converging lines of evidence Joseph Henrich, Robert Boyd, Richard McElreath, PNAS PLUS (AUTHOR SUMMARIES) Michael Gurven, Peter J. Richerson, Jean Ensminger, Michael Alvard, Abigail Barr, H. Clark Barrett, Alexander PHYSICAL SCIENCES Bolyanatz, Colin F. Camerer, Juan-Camilo Cardenas, Ernst Fehr, Herbert M. Gintis, Francisco Gil-White, APPLIED MATHEMATICS Edwins Laban Gwako, Natalie Henrich, Kim Hill, 10144 Conservation of complex knotting and slipknotting Carolyn Lesorogol, John Q. Patton, Frank W. Marlowe, patterns in proteins David P. Tracer, and John Ziker Joanna I. Sułkowska, Eric J. Rawdon, Kenneth C. Millett, Jose N. Onuchic, and Andrzej Stasiak Free online through the PNAS open access option. See full research article on page E1715 of www.pnas.org

PNAS u June 26, 2012 u vol. 109 u no. 26 u iii–ix Downloaded by guest on October 1, 2021 APPLIED PHYSICAL SCIENCES 10146 Asymmetrical roles of zinc fingers in dynamic 10136 Compressive fluorescence microscopy for biological DNA-scanning process by the inducible and hyperspectral imaging transcription factor Egr-1 Vincent Studer, Jérome Bobin, Makhlad Chahid, Hamed Levani Zandarashvili, Dana Vuzman, Alexandre Esadze, Shams Mousavi, Emmanuel Candes, and Maxime Dahan Yuki Takayama, Debashish Sahu, Yaakov Levy, See full research article on page E1679 of www.pnas.org and Junji Iwahara See full research article on page E1724 of www.pnas.org EARTH, ATMOSPHERIC, AND PLANETARY SCIENCES 10148 Structural basis of histidine kinase autophosphorylation 10138 Fluvial landscapes of the Harappan civilization deduced by integrating genomics, molecular dynamics, Liviu Giosan, Peter D. Clift, Mark G. Macklin, Dorian Q. and mutagenesis Fuller, Stefan Constantinescu, Julie A. Durcan, Thomas Angel E. Dago, Alexander Schug, Andrea Procaccini, Stevens, Geoff A. T. Duller, Ali R. Tabrez, Kavita James A. Hoch, Martin Weigt, and Hendrik Szurmant Gangal, Ronojoy Adhikari, Anwar Alizai, Florin Filip, See full research article on page E1733 of www.pnas.org Sam VanLaningham, and James P. M. Syvitski See full research article on page E1688 of www.pnas.org

10152 Warming accelerates decomposition of decades-old ECOLOGY carbon in forest soils Francesca M. Hopkins, Margaret S. Torn, 10150 Mass spectral molecular networking of living and Susan E. Trumbore microbial colonies See full research article on page E1753 of www.pnas.org Jeramie Watrous, Patrick Roach, Theodore Alexandrov, Brandi S. Heath, Jane Y. Yang, Roland D. Kersten, Menno van der Voort, Kit Pogliano, Harald Gross, ENVIRONMENTAL SCIENCES Jos M. Raaijmakers, Bradley S. Moore, Julia Laskin, 10154 Influence of cobalamin scarcity on diatom molecular Nuno Bandeira, and Pieter C. Dorrestein physiology and identification of a cobalamin See Commentary on page 10128 acquisition protein See full research article on page E1743 of www.pnas.org Erin M. Bertrand, Andrew E. Allen, Christopher L. Dupont, Trina M. Norden-Krichmar, Jing Bai, Ruben E. Valas, and Mak A. Saito ENVIRONMENTAL SCIENCES See full research article on page E1762 of www.pnas.org 10152 Warming accelerates decomposition of decades-old SOCIAL SCIENCES carbon in forest soils Francesca M. Hopkins, Margaret S. Torn, ENVIRONMENTAL SCIENCES and Susan E. Trumbore See full research article on page E1753 of www.pnas.org 10138 Fluvial landscapes of the Harappan civilization Liviu Giosan, Peter D. Clift, Mark G. Macklin, Dorian Q. Fuller, Stefan Constantinescu, Julie A. Durcan, Thomas 10154 Influence of cobalamin scarcity on diatom molecular Stevens, Geoff A. T. Duller, Ali R. Tabrez, Kavita physiology and identification of a cobalamin Gangal, Ronojoy Adhikari, Anwar Alizai, Florin Filip, acquisition protein Sam VanLaningham, and James P. M. Syvitski Erin M. Bertrand, Andrew E. Allen, Christopher L. Dupont, See full research article on page E1688 of www.pnas.org Trina M. Norden-Krichmar, Jing Bai, Ruben E. Valas, and Mak A. Saito BIOLOGICAL SCIENCES See full research article on page E1762 of www.pnas.org APPLIED BIOLOGICAL SCIENCES 10140 Nanoparticle-based therapy in an in vivo microRNA-155 MICROBIOLOGY (miR-155)-dependent mouse model of lymphoma Imran A. Babar, Christopher J. Cheng, Carmen J. Booth, 10156 A subset of group A-like var genes encodes the malaria Xianping Liang, Joanne B. Weidhaas, W. Mark Saltzman, parasite ligands for binding to human brain and Frank J. Slack endothelial cells See full research article on page E1695 of www.pnas.org Antoine Claessens, Yvonne Adams, Ashfaq Ghumra, Gabriella Lindergard, Caitlin C. Buchan, Cheryl Andisi, Peter C. Bull, Sachel Mok, Archna P. Gupta, Christian W. BIOCHEMISTRY Wang, Louise Turner, Mònica Arman, Ahmed Raza, 10142 Evolutionary selection of enzymatically synthesized Zbynek Bozdech, and J. Alexandra Rowe semiconductors from biomimetic mineralization vesicles See Commentary on page 10130 Lukmaan A. Bawazer, Michi Izumi, Dmitriy Kolodin, See full research article on page E1772 of www.pnas.org James R. Neilson, Birgit Schwenzer, and Daniel E. Morse See full research article on page E1705 of www.pnas.org 10158 A restricted subset of var genes mediates adherence of Plasmodium falciparum-infected erythrocytes to brain BIOPHYSICS AND COMPUTATIONAL BIOLOGY endothelial cells 10144 Conservation of complex knotting and slipknotting Marion Avril, Abhai K. Tripathi, Andrew J. Brazier, Cheryl patterns in proteins Andisi, Joel H. Janes, Vijaya L. Soma, David J. Sullivan, Jr., Joanna I. Sułkowska, Eric J. Rawdon, Kenneth C. Millett, Peter C. Bull, Monique F. Stins, and Joseph D. Smith Jose N. Onuchic, and Andrzej Stasiak See Commentary on page 10130 See full research article on page E1715 of www.pnas.org See full research article on page E1782 of www.pnas.org

iv u www.pnas.org Downloaded by guest on October 1, 2021 10160 Plasmodium falciparum erythrocyte membrane protein 10210 Reversible switching between superhydrophobic states 1 domain cassettes 8 and 13 are associated with on a hierarchically structured surface severe malaria in children Tuukka Verho, Juuso T. Korhonen, Lauri Sainiemi, Ville Thomas Lavstsen, Louise Turner, Fredy Saguti, Pamela Jokinen, Chris Bower, Kristian Franze, Sami Franssila, Magistrado, Thomas S. Rask, Jakob S. Jespersen, Piers Andrew, Olli Ikkala, and Robin H. A. Ras Christian W. Wang, Sanne S. Berger, Vito Baraka, Andrea M. Marquard, Andaine Seguin-Orlando, Eske Willerslev, M. Thomas P. Gilbert, John Lusingu, CHEMISTRY and Thor G. Theander 10214 Neural stem cell specific fluorescent chemical probe See Commentary on page 10130 binding to FABP7 See full research article on page E1791 of www.pnas.org Seong-Wook Yun, Cheryl Leong, Duanting Zhai, Yee Ling Tan, Linda Lim, Xuezhi Bi, Jae-Jung Lee, Han Jo Kim, SYSTEMS BIOLOGY Nam-Young Kang, Shin Hui Ng, Lawrence W. Stanton, 10162 New meta-analysis tools reveal common transcriptional and Young-Tae Chang regulatory basis for multiple determinants of behavior 10218 Direct chemical evidence for eumelanin pigment from Seth A. Ament, Charles A. Blatti, Cedric Alaux, Marsha M. the Jurassic period Wheeler, Amy L. Toth, Yves Le Conte, Greg J. Hunt, Ernesto Keely Glass, Shosuke Ito, Philip R. Wilby, Takayuki Sota, Guzmán-Novoa, Gloria DeGrandi-Hoffman, Jose Luis Atsushi Nakamura, C. Russell Bowers, Jakob Vinther, Uribe-Rubio, Gro V. Amdam, Robert E. Page, Jr., Sandra L. Suryendu Dutta, Roger Summons, Derek E. G. Briggs, Rodriguez-Zas, Gene E. Robinson, and Saurabh Sinha Kazumasa Wakamatsu, and John D. Simon See full research article on page E1801 of www.pnas.org

10224 Enhancing dissociative chemisorption of H2O on Cu(111) via vibrational excitation PERSPECTIVE Bin Jiang, Xuefeng Ren, Daiqian Xie, and Hua Guo 10228 Anions dramatically enhance proton transfer through 10164 Earthquake triggering and large-scale geologic storage aqueous interfaces of carbon dioxide Himanshu Mishra, Shinichi Enami, Robert J. Nielsen, Mark D. Zoback and Steven M. Gorelick Michael R. Hoffmann, William A. Goddard III, and Agustín J. Colussi

PHYSICAL SCIENCES 10233 Elemental nitrogen partitioning in dense interstellar clouds Julien Daranlot, Ugo Hincelin, Astrid Bergeat, Michel Costes, APPLIED MATHEMATICS Jean-Christophe Loison, Valentine Wakelam, 10169 Cloaked electromagnetic, acoustic, and quantum and Kevin M. Hickson fi ampli ers via transformation optics 10328 Hydrodynamic trapping of molecules in lipid bilayers Allan Greenleaf, Yaroslav Kurylev, Matti Lassas, Peter Jönsson, James McColl, Richard W. Clarke, Victor P. Ulf Leonhardt, and Gunther Uhlmann Ostanin, Bengt Jönsson, and David Klenerman APPLIED PHYSICAL SCIENCES 10175 Electron transfer-based combination therapy of cisplatin EARTH, ATMOSPHERIC, AND PLANETARY SCIENCES p with tetramethyl- -phenylenediamine for ovarian, 10239 Sound velocities of Fe and Fe-Si alloy in the cervical, and lung cancers Earth’score Ting Luo, Jianqing Yu, Jenny Nguyen, Chun-Rong Wang, Zhu Mao, Jung-Fu Lin, Jin Liu, Ahmet Alatas, Lili Gao, Robert G. Bristow, David A. Jaffray, Xiao Zhen Zhou, Jiyong Zhao, and Ho-Kwang Mao Kun Ping Lu, and Qing-Bin Lu 10181 Phase transitions in physiologic coupling Ronny P. Bartsch, Aicko Y. Schumann, Jan W. Kantelhardt, ENGINEERING Thomas Penzel, and Plamen Ch. Ivanov 10334 Independent regulation of tumor cell migration by matrix stiffness and confinement 10187 Analytical theory of polymer-network-mediated Amit Pathak and Sanjay Kumar interaction between colloidal particles Lorenzo Di Michele, Alessio Zaccone, and Erika Eiser 10193 Molecular simulations elucidate electric field actuation ENVIRONMENTAL SCIENCES in swollen liquid crystal elastomers 10403 Leaf fossil record suggests limited influence of  Gregor Skacej and Claudio Zannoni atmospheric CO2 on terrestrial productivity prior to angiosperm evolution 10199 Trimodal low-dose X-ray tomography C. Kevin Boyce and Maciej A. Zwieniecki I. Zanette, M. Bech, A. Rack, G. Le Duc, P. Tafforeau, C. David, J. Mohr, F. Pfeiffer, and T. Weitkamp 10205 Multiconfigurational nature of 5f orbitals in uranium and PHYSICS plutonium intermetallics 10245 Anomalous front broadening during spontaneous C. H. Booth, Yu Jiang, D. L. Wang, J. N. Mitchell, imbibition in a matrix with elongated pores P. H. Tobash, E. D. Bauer, M. A. Wall, P. G. Allen, Simon Gruener, Zeinab Sadjadi, Helen E. Hermes, Andriy V. D. Sokaras, D. Nordlund, T.-C. Weng, M. A. Torrez, Kityk, Klaus Knorr, Stefan U. Egelhaaf, Heiko Rieger, and J. L. Sarrao and Patrick Huber

PNAS u June 26, 2012 u vol. 109 u no. 26 u v Downloaded by guest on October 1, 2021 10564 Scale invariance in the dynamics of 10293 Late Middle Eocene primate from Myanmar and the spontaneous behavior initial anthropoid colonization of Africa Alex Proekt, Jayanth R. Banavar, Amos Maritan, Yaowalak Chaimanee, Olivier Chavasseau, K. Christopher and Donald W. Pfaff Beard, Aung Aung Kyaw, Aung Naing Soe, Chit Sein, Vincent Lazzari, Laurent Marivaux, Bernard Marandat, Myat Swe, Mana Rugbumrung, Thit Lwin, Xavier Valentin, SOCIAL SCIENCES Zin-Maung-Maung-Thein, and Jean-Jacques Jaeger See Commentary on page 10132 ANTHROPOLOGY APPLIED BIOLOGICAL SCIENCES 10251 Delayed paternal age of reproduction in humans is associated with longer telomeres across two 10298 Enhanced cellulose degradation by targeted integration generations of descendants of a cohesin-fused β-glucosidase into the Clostridium thermocellum Dan T. A. Eisenberg, M. Geoffrey Hayes, cellulosome and Christopher W. Kuzawa Gilad Gefen, Michael Anbar, Ely Morag, Raphael Lamed, and Edward A. Bayer ECONOMIC SCIENCES BIOCHEMISTRY 10257 Documenting the birth of a financial economy Tavneet Suri, William Jack, and Thomas M. Stoker 10304 Plant tropane alkaloid biosynthesis evolved independently in the Solanaceae and Erythroxylaceae Jan Jirschitzka, Gregor W. Schmidt, Michael Reichelt, ENVIRONMENTAL SCIENCES Bernd Schneider, Jonathan Gershenzon, 10287 Aboriginal hunting buffers climate-driven fire-size and John Charles D’Auria variability in Australia’s spinifex grasslands 10310 Arylsulfatase G inactivation causes loss of heparan Rebecca Bliege Bird, Brian F. Codding, Peter G. Kauhanen, sulfate 3-O-sulfatase activity and mucopolysaccharidosis and Douglas W. Bird in mice Björn Kowalewski, William C. Lamanna, Roger Lawrence, POLITICAL SCIENCES Markus Damme, Stijn Stroobants, Michael Padva, Ina Kalus, 10263 Geographic axes and the persistence of cultural diversity Marc-André Frese, Torben Lübke, Renate Lüllmann-Rauch, David D. Laitin, Joachim Moortgat, Rudi D’Hooge, Jeffrey D. Esko, and Thomas Dierks and Amanda Lea Robinson 10316 An IFN-γ–stimulated ATF6–C/EBP-β–signaling pathway critical for the expression of Death Associated Protein PSYCHOLOGICAL AND COGNITIVE SCIENCES Kinase 1 and induction of autophagy 10409 Iterated Prisoner’s Dilemma contains strategies Padmaja Gade, Girish Ramachandran, Uday B. Maachani, that dominate any evolutionary opponent Mark A. Rizzo, Tetsuya Okada, Ron Prywes, Alan S. Cross, William H. Press and Freeman J. Dyson Kazutoshi Mori, and Dhananjaya V. Kalvakolanu See Commentary on page 10134 10322 Roco kinase structures give insights into the mechanism of Parkinson disease-related leucine-rich-repeat kinase 2 mutations BIOLOGICAL SCIENCES Bernd K. Gilsbach, Franz Y. Ho, Ingrid R. Vetter, Peter J. M. van Haastert, Alfred Wittinghofer, and Arjan Kortholt AGRICULTURAL SCIENCES 10269 Neurokinin Bs and neurokinin B receptors in BIOPHYSICS AND COMPUTATIONAL BIOLOGY zebrafish-potential role in controlling fish reproduction 10175 Electron transfer-based combination therapy of cisplatin Jakob Biran, Ori Palevitch, Shifra Ben-Dor, with tetramethyl-p-phenylenediamine for ovarian, and Berta Levavi-Sivan cervical, and lung cancers 10275 Diverse genetic basis of field-evolved resistance to Ting Luo, Jianqing Yu, Jenny Nguyen, Chun-Rong Wang, Bt cotton in cotton bollworm from China Robert G. Bristow, David A. Jaffray, Xiao Zhen Zhou, Haonan Zhang, Wen Tian, Jing Zhao, Lin Jin, Jun Yang, Kun Ping Lu, and Qing-Bin Lu Chunhui Liu, Yihua Yang, Shuwen Wu, Kongming Wu, 10328 Hydrodynamic trapping of molecules in lipid bilayers Jinjie Cui, Bruce E. Tabashnik, and Yidong Wu Peter Jönsson, James McColl, Richard W. Clarke, Victor P. 10281 Presence of tannins in sorghum grains is conditioned by Ostanin, Bengt Jönsson, and David Klenerman different natural alleles of Tannin1 10334 Independent regulation of tumor cell migration by Yuye Wu, Xianran Li, Wenwen Xiang, Chengsong Zhu, matrix stiffness and confinement Zhongwei Lin, Yun Wu, Jiarui Li, Satchidanand Pandravada, Amit Pathak and Sanjay Kumar Dustan D. Ridder, Guihua Bai, Ming L. Wang, Harold N. Trick, Scott R. Bean, Mitchell R. Tuinstra, Tesfaye T. Tesso, 10340 Genomics-aided structure prediction and Jianming Yu Joanna I. Sułkowska, Faruck Morcos, Martin Weigt, Terence Hwa, and José N. Onuchic ANTHROPOLOGY 10346 Anomalous diffusion and dynamical correlation 10287 Aboriginal hunting buffers climate-driven fire-size between the side chains and the main chain variability in Australia’s spinifex grasslands of proteins in their native state Rebecca Bliege Bird, Brian F. Codding, Peter G. Kauhanen, Yoann Cote, Patrick Senet, Patrice Delarue, and Douglas W. Bird Gia G. Maisuradze, and Harold A. Scheraga

vi u www.pnas.org Downloaded by guest on October 1, 2021 10352 Mechanistic basis for low threshold mechanosensitivity 10403 Leaf fossil record suggests limited influence of + in voltage-dependent K channels atmospheric CO2 on terrestrial productivity Daniel Schmidt, Josefina del Mármol, prior to angiosperm evolution and Roderick MacKinnon C. Kevin Boyce and Maciej A. Zwieniecki

10358 Bridging the gaps in design methodologies by 10409 Iterated Prisoner’s Dilemma contains strategies evolutionary optimization of the stability and that dominate any evolutionary opponent proficiency of designed Kemp eliminase KE59 William H. Press and Freeman J. Dyson Olga Khersonsky, Gert Kiss, Daniela Röthlisberger, See Commentary on page 10134 Orly Dym, Shira Albeck, Kendall N. Houk, 10414 Evolutionary optimum for male sexual traits David Baker, and Dan S. Tawfik characterized using the multivariate – 10364 Impact of branching on the elasticity of actin networks Robertson Price Identity Thomas Pujol, Olivia du Roure, Marc Fermigier, Matthieu Delcourt, Mark W. Blows, J. David Aguirre, and Julien Heuvingh and Howard D. Rundle 10420 Dynamic epistasis for different alleles of the same gene Lin Xu, Brandon Barker, and Zhenglong Gu CELL BIOLOGY 10214 Neural stem cell specific fluorescent chemical probe 10426 Evolution of Fe/S cluster biogenesis in the anaerobic Blastocystis binding to FABP7 parasite Seong-Wook Yun, Cheryl Leong, Duanting Zhai, Yee Ling Anastasios D. Tsaousis, Sandrine Ollagnier de Choudens, Tan, Linda Lim, Xuezhi Bi, Jae-Jung Lee, Han Jo Kim, Eleni Gentekaki, Shaojun Long, Daniel Gaston, Alexandra Nam-Young Kang, Shin Hui Ng, Lawrence W. Stanton, Stechmann, Daniel Vinella, Béatrice Py, Marc Fontecave, š and Young-Tae Chang Frédéric Barras, Julius Luke , and Andrew J. Roger 10432 High natural prevalence of a fungal prion 10370 Cysteine desulfurase Nfs1 and Pim1 protease Alfons J. M. Debets, Henk J. P. Dalstra, Marijke Slakhorst, control levels of Isu, the Fe-S cluster Bertha Koopmanschap, Rolf F. Hoekstra, and Sven J. Saupe biogenesis scaffold Ji-Yoon Song, Jaroslaw Marszalek, and Elizabeth Anne Craig

10376 Anoctamin 1 (Tmem16A) Ca2+-activated chloride GENETICS channel stoichiometrically interacts with an 10438 Analysis of neural subtypes reveals selective ezrin–radixin–moesin network mitochondrial dysfunction in dopaminergic neurons Patricia Perez-Cornejo, Avanti Gokhale, Charity Duran, from parkin mutants Yuanyuan Cui, Qinghuan Xiao, H. Criss Hartzell, Jonathon L. Burman, Selina Yu, Angela C. Poole, and Victor Faundez Richard B. Decal, and Leo Pallanck 10382 Gadkin negatively regulates cell spreading and motility 10444 Repeat associated small RNAs vary among parents via sequestration of the actin-nucleating and following hybridization in maize ARP2/3 complex Wesley T. Barber, Wei Zhang, Hlaing Win, Kranthi K. Varala, Tanja Maritzen, Tobias Zech, Michael R. Schmidt, Eberhard Jane E. Dorweiler, Matthew E. Hudson, Krause, Laura M. Machesky, and Volker Haucke and Stephen P. Moose

10388 Perivascular-resident macrophage-like melanocytes in 10450 Cdc28 kinase activity regulates the basal transcription the inner ear are essential for the integrity of the machinery at a subset of genes intrastrial fluid–blood barrier Pierre Chymkowitch, Vegard Eldholm, Susanne Lorenz, Wenjing Zhang, Min Dai, Anders Fridberger, Ahmed Hassan, Christine Zimmermann, Jessica M. Lindvall, Magnar Bjørås, Jacqueline DeGagne, Lingling Neng, Fei Zhang, Wenxuan He, Leonardo A. Meza-Zepeda, and Jorrit M. Enserink Tianying Ren, Dennis Trune, Manfred Auer, and Xiaorui Shi IMMUNOLOGY 10456 CD45-deficient severe combined immunodeficiency ECOLOGY caused by uniparental disomy 10394 Biodiversity impacts ecosystem productivity as much as Joseph L. Roberts, Rebecca H. Buckley, Biao Luo, Jianming resources, disturbance, or herbivory Pei, Alla Lapidus, Suraj Peri, Qiong Wei, Jinwook Shin, David Tilman, Peter B. Reich, and Forest Isbell Roberta E. Parrott, Roland L. Dunbrack, Jr., Joseph R. Testa, Xiao-Ping Zhong, and David L. Wiest 10398 Rapidly growing tropical trees mobilize remarkable Lactobacillus amounts of nitrogen, in ways that differ surprisingly 10462 Abating colon cancer polyposis by acidophilus fi among species de cient in lipoteichoic acid Ann E. Russell and James W. Raich Khashayarsha Khazaie, Mojgan Zadeh, Mohammad W. Khan, Praveen Bere, Fotini Gounari, Kirsten Dennis, Nichole R. Blatner, Jennifer L. Owen, Todd R. Klaenhammer, EVOLUTION and Mansour Mohamadzadeh 10251 Delayed paternal age of reproduction in humans is 10468 Regulatory T cells use programmed death 1 ligands associated with longer telomeres across two to directly suppress autoreactive B cells in vivo generations of descendants Janine Gotot, Catherine Gottschalk, Sonny Leopold, Dan T. A. Eisenberg, M. Geoffrey Hayes, Percy A. Knolle, Hideo Yagita, Christian Kurts, and Christopher W. Kuzawa and Isis Ludwig-Portugall

PNAS u June 26, 2012 u vol. 109 u no. 26 u vii Downloaded by guest on October 1, 2021 10474 Opposing roles for RhoH GTPase during T-cell migration 10534 Expression of MALT1 oncogene in hematopoietic and activation stem/progenitor cells recapitulates the pathogenesis Christina M. Baker, William A. Comrie, Young-Min Hyun, of human lymphoma in mice Hung-Li Chung, Christine A. Fedorchuk, Kihong Lim, Carolina Vicente-Dueñas, Lorena Fontán, Ines Cord Brakebusch, James L. McGrath, Richard E. Waugh, Gonzalez-Herrero, Isabel Romero-Camarero, Victor Segura, Martin Meier-Schellersheim, and Minsoo Kim M. Angela Aznar, Esther Alonso-Escudero, Elena Campos-Sanchez, Lucía Ruiz-Roca, Marcos Barajas-Diego, 10480 NLRP3 inflammasome induces chemotactic immune Ainara Sagardoy, Jose I. Martinez-Ferrandis, Fernando cell migration to the CNS in experimental Abollo-Jimenez, Cristina Bertolo, Ivan Peñuelas, Francisco J. autoimmune encephalomyelitis Garcia-Criado, María B. García-Cenador, Thomas Tousseyn, Makoto Inoue, Kristi L. Williams, Michael D. Gunn, Xabier Agirre, Felipe Prosper, Federico Garcia-Bragado, and Mari L. Shinohara Ellen D. McPhail, Izidore S. Lossos, Ming-Qing Du, Teresa Flores, Jesus M. Hernandez-Rivas, Marcos Gonzalez, 10486 Presensitizing with a Toll-like receptor 3 ligand Antonio Salar, Beatriz Bellosillo, Eulogio Conde, Reiner impairs CD8 T-cell effector differentiation Siebert, Xavier Sagaert, Cesar Cobaleda, Isidro and IL-33 responsiveness Sanchez-Garcia, and Jose A. Martinez-Climent Soo Mun Ngoi, Marie-Clare St. Rose, Antoine M. Menoret, Dirk E. Smith, Michael G. Tovey, Adam J. Adler, and Anthony T. Vella MICROBIOLOGY

10492 Autocrine/paracrine TGF-β1 inhibits Langerhans 10540 Strategy for directing combinatorial genome Escherichia coli cell migration engineering in Aleh Bobr, Botond Z. Igyarto, Krystal M. Haley, Ming O. Li, Nicholas R. Sandoval, Jaoon Y. H. Kim, Tirzah Y. Glebes, Richard A. Flavell, and Daniel H. Kaplan Philippa J. Reeder, Hanna R. Aucoin, Joseph R. Warner, and Ryan T. Gill 10498 Revised mechanism of complement lectin-pathway 10546 Cleavage of a putative metal permease in Chlamydia activation revealing the role of serine protease trachomatis yields an iron-dependent MASP-1 as the exclusive activator of MASP-2 transcriptional repressor Dávid Héja, Andrea Kocsis, József Dobó, Katalin Christopher C. Thompson, Sophie S. Nicod, Denise S. Szilágyi, Róbert Szász, Péter Závodszky, Malcolm, Scott S. Grieshaber, and Rey A. Carabeo Gábor Pál, and Péter Gál 10552 PGRP-LB is a maternally transmitted immune milk protein that influences symbiosis and parasitism MEDICAL SCIENCES in tsetse’s offspring 10504 Hypoxia-inducible factor 1 transcriptional activity Jingwen Wang and Serap Aksoy in endothelial cells is required for acute phase 10558 Acetylation modulates cellular distribution and DNA cardioprotection induced by ischemic preconditioning sensing ability of interferon-inducible protein IFI16 Kakali Sarkar, Zheqing Cai, Rigu Gupta, Nirmal Parajuli, Tuo Li, Benjamin A. Diner, Jin Chen, and Ileana M. Cristea Karen Fox-Talbot, Medha S. Darshan, Frank J. Gonzalez, and Gregg L. Semenza NEUROSCIENCE 10510 Patched dependence receptor triggers apoptosis 10564 Scale invariance in the dynamics of through ubiquitination of caspase-9 spontaneous behavior Joanna Fombonne, Pierre-Antoine Bissey, Catherine Guix, Alex Proekt, Jayanth R. Banavar, Amos Maritan, Rémy Sadoul, Chantal Thibert, and Patrick Mehlen and Donald W. Pfaff 10516 A discrete population of squamocolumnar junction cells 10570 Mechanisms of white matter changes induced implicated in the pathogenesis of cervical cancer by meditation Michael Herfs, Yusuke Yamamoto, Anna Laury, Xia Wang, Yi-Yuan Tang, Qilin Lu, Ming Fan, Yihong Yang, Marisa R. Nucci, Margaret E. McLaughlin-Drubin, Karl and Michael I. Posner Münger, Sarah Feldman, Frank D. McKeon, Wa Xian, and Christopher P. Crum 10575 Memory stabilization with targeted reactivation during human slow-wave sleep 10522 Distinct DNA methylomes of newborns and centenarians Eelco V. van Dongen, Atsuko Takashima, Markus Barth, Holger Heyn, Ning Li, Humberto J. Ferreira, Sebastian Jascha Zapp, Lothar R. Schad, Ken A. Paller, Moran, David G. Pisano, Antonio Gomez, Javier Diez, and Guillén Fernández Jose V. Sanchez-Mut, Fernando Setien, F. Javier Carmona, Annibale A. Puca, Sergi Sayols, Miguel A. Pujana, 10581 Small molecule-induced cytosolic activation of protein Jordi Serra-Musach, Isabel Iglesias-Platas, Francesc kinase Akt rescues ischemia-elicited neuronal death Formiga, Agustin F. Fernandez, Mario F. Fraga, Hakryul Jo, Subhanjan Mondal, Dewar Tan, Eiichiro Nagata, Simon C. Heath, Alfonso Valencia, Ivo G. Gut, Shunya Takizawa, Alok K. Sharma, Qingming Hou, Kumaran Jun Wang, and Manel Esteller Shanmugasundaram, Amit Prasad, Joe K. Tung, Alexander O. Tejeda, Hengye Man, Alan C. Rigby, and Hongbo R. Luo 10528 Specific mitochondrial DNA mutation in mice regulates diabetes and lymphoma development Osamu Hashizume, Akinori Shimizu, Mutsumi Yokota, PHYSIOLOGY Atsuko Sugiyama, Kazuto Nakada, Hiroyuki Miyoshi, Makiko 10181 Phase transitions in physiologic coupling Itami, Miki Ohira, Hiroki Nagase, Keizo Takenaga, Ronny P. Bartsch, Aicko Y. Schumann, Jan W. Kantelhardt, and Jun-Ichi Hayashi Thomas Penzel, and Plamen Ch. Ivanov

viii u www.pnas.org Downloaded by guest on October 1, 2021 10587 Stress and aging induce distinct polyQ protein IMMUNOLOGY aggregation states 10605 Nucleotide oligomerization domain-containing proteins Lorenza E. Moronetti Mazzeo, Devin Dersh, Marco Boccitto, instruct T cell helper type 2 immunity through Robert G. Kalb, and Todd Lamitina stromal activation Joao G. Magalhaes, Stephen J. Rubino, Leonardo H. PLANT BIOLOGY Travassos, Lionel Le Bourhis, Wei Duan, Gernot Sellge, Karou Geddes, Colin Reardon, Matthias Lechmann, 10593 Reconstitution of abscisic acid activation of SLAC1 anion Leticia A. Carneiro, Thirumahal Selvanantham, Jorg H. Fritz, channel by CPK6 and OST1 kinases and branched ABI1 Betsy C. Taylor, David Artis, Tak Wah Mak, Michael R. PP2C phosphatase action Comeau, Michael Croft, Stephen E. Girardin, Benjamin Brandt, Dennis E. Brodsky, Shaowu Xue, Juntaro and Dana J. Philpott Negi, Koh Iba, Jaakko Kangasjärvi, Majid Ghassemian, Aaron B. Stephan, Honghong Hu, and Julian I. Schroeder PLANT BIOLOGY PSYCHOLOGICAL AND COGNITIVE SCIENCES 10606 Multiple organellar RNA editing factor (MORF) family 10599 Conscious updating is a rhythmic process proteins are required for RNA editing in mitochondria Ramakrishna Chakravarthi and Rufin VanRullen and plastids of plants Mizuki Takenaka, Anja Zehrmann, Daniil Verbitskiy, Matthias Kugelmann, Barbara Härtel, CORRECTIONS and Axel Brennicke

BIOPHYSICS AND COMPUTATIONAL BIOLOGY xi Subscription Form 10605 Structure, function and inhibition of the two- and three-domain 4Fe-4S IspG proteins Yi-Liang Liu, Francisco Guerra, Ke Wang, Weixue Wang, Supplement 1 Jikun Li, Cancan Huang, Wei Zhu, Kevin Houlihan, Zhi Li, Yong Zhang, Satish K. Nair, and Eric Oldfield ARTHUR M. SACKLER COLLOQUIUM OF THE NATIONAL ECOLOGY ACADEMY OF SCIENCES 10605 More closely related species are more ecologically similar in an experimental test 10607–10740 In the Light of Evolution VI: Jean H. Burns and Sharon Y. Strauss Brain and Behavior

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