Posted on Authorea 15 Jun 2020 | The copyright holder is the author/funder. All rights reserved. No reuse without permission. | https://doi.org/10.22541/au.159225357.75853734 | This a preprint and has not been peer reviewed. Data may be preliminary. i el rmdl a rayseicsg ntmoa oei u td group. study our in bone temporal in sign specific any (p=0,50). Keywords: or groups ear the middle between or difference cells no air findings were patients. imaging there 16 bone and included Temporal system and Conclusion: patients. grading CT the a chest of to any in in according findings observed compared no was were involvement had bone 2 temporal group obvious patients, No 26 included and findings CT chest imaging. bone temporal Results: in sign specific any Also cells. measures: outcome Main evaluated. were imaging tomography Participants: bone temporal and test PCR positive Settings: study Retrospective Design: group. study our in bone temporal Objective: the bone. in sign temporal specific the any affect or not ear ABSTRACT: middle bone does the SARS-CoV-2 temporal or obvious The cells air No system Conclusion: mastoid grading patients. in a (p=0,50). effusion 16 to CT groups of according included chest sign the compared and no specific were between was CT had findings difference There imaging chest 1 no bone in Group Temporal was bone findings temporal findings. there patients. no in the CT and sign of had chest any specific 2 their in any group to observed Also A was patients, according involvement cells. measures: groups 26 air two outcome included mastoid into Main and and divided ear findings imaging. were middle Patients bone the in temporal Results: effusion with imaging evaluate imaging. tomography patients to bone COVID-19 created temporal was positive our and system PCR of test grading database PCR 42 the positive Participants: Using a with Settings: evaluated. infection study were COVID-19 Retrospective with Design: patients COVID-19 hospital, in pandemic findings tertiary bone temporal investigate To Objective: Abstract 2020 15, June 4 3 2 1 Guner Hatice yuce COVID-19 INVOLMENT IN BONE TEMPORAL THE OF INVESTIGATION idrmByztUniversitesi Beyazit Medicine Yildirim of Faculty University Hospital Beyazit City Yildirim Ankara Health Hastanesi of Sehir Ministry Ankara Bakanligi Saglik TC Islamoglu ˙ ainswr iie notogop codn otercetC nig.Gop1hdspecific had 1 Group findings. CT chest their to according groups two into divided were Patients sn aaaeo u etaypnei optl ainswt OI-9ifcinwt a with infection COVID-19 with patients hospital, pandemic tertiary our of database Using oivsiaetmoa oefidnsi COVID-19 in findings bone temporal investigate To OI-9 eprlbn,SR-o-,msod ideear middle mastoid, SARS-CoV-2, bone, temporal COVID-19, h ASCV2de o ffc h eprlbn.Teewsn ino ffso nmastoid in effusion of sign no was There bone. temporal the effect not does SARS-CoV-2 The 2PRpstv OI-9ptet ihtmoa oeimaging. bone temporal with patients COVID-19 positive PCR 42 4 1 ueAyhan Muge , rdn ytmwscetdt vlaeeuini ideeradmsodair mastoid and ear middle in effusion evaluate to created was system Grading 2 aiBercin Sami , 3 1 yeKy Kalem Kaya Ayse , 4 icnKayaaslan Bircan , 4 and , Posted on Authorea 15 Jun 2020 | The copyright holder is the author/funder. All rights reserved. No reuse without permission. | https://doi.org/10.22541/au.159225357.75853734 | This a preprint and has not been peer reviewed. Data may be preliminary. .1 B,Ciao L.Frcmaio fgop1adgop2i em fgaigsoe ardsimple Paired a score, grading of terms significant. in Sciences statistically 2 considered Social Consideration group was for Ethical and 0.05 Package 1 < (Statistical group P program of used. software comparison was 21.0 For t-test version IL). Chicago, SPSS IBM, the v.21, using analyzed were was Data Groups COVID-19. of signs no analysis typical negative Statistical had had separately patients) (27 patients) ear 1 scores. (15 middle Group 2 grading right findings. group for was8. or (CT) and compared chest score left COVID-19 in total findings and for Maximum to signs effusion cells due radiological inflammation. evaluate groups mastoid two %100 to right into 2= used divided or COVID-19, patients and was left The besides inflammation system for partial infection Grading as 1= other study. applied inflammation, active the is no surgery, from score 0= ear excluded These media, are imagines. eyes. otitis vertigo in around chronic or fullness smoker of or loss, history headache hearing a like bone imaging hospitalization, with temporal during to patients CT has bone lead cranial The who which temporal or those including symptoms scans imaging of and axial infection, membrane selection CT evaluated. COVID-19 tympanic paranasal the active were normal scans, had to (CT) (CT) patients due tomography tomography All patients with computed computed scans. 789 patients temporal temporal The total had and Patients patients. through test 42 imaging. included of PCR were comprised positive subjects group a 42 study with The study. infection observational COVID-19 retrospective a was patients. This positive COVID-19 the of and METHODS: finding imaging AND radiological cells temporal MATERIAL any mastoid the there investigated effect Is the we virus of study effusion? the our or cells cochlea? Does media In hair or otitis ear. ear that cause middle on shown it or virus was Does mastoid SARS-CoV-2 it coronaviruses? in of other study effect like a unclear. ear about In is middle information mechanism no the seen. is But be directly There COVID-19. can can hearing in losses sensorineural injured They hearing cause result be viruses can mixed can loss. Generally or cochlea and damage hearing hearingloss. conductive ear to bilateral inner but leading cause or infection; loss and fungal unilateral responses or inflammatory detected acquired, bacterial stimulate secondary be can or structures, can congenital ear effusion inner cause and associated damage effusion ear can middle result infections the inflammation Viral of cell process air inflammatory mastoid an and tomography. is ear computed media by Middle poten- otitis as Acute effusion. implicated in media. an been involved have otitis with air viruses acute is mastoid respiratory of and mucosa as agents ear coronovirus Airway tial and middle virus tube, syncytial mucosa. eustachian respiratory lining contaminated. respiratory Rhinovirus, mucosa be by respiratory might covered nose the but the is if involved known but, is system not virus. system lungs cell is theSARS-CoV-2 of in it of air shortness settle but concentrations and mastoid generally COVID-19 high cough and Disease for Fever, reservoirs ear pneumonia. certain. be Middle of not to are result shown Health symptoms a been even World have as disease nasopharynx frequently the and observed worldwide. about is unknown the breath of COVID-19wasthe across lot 2019). spread a disease is outbreak Wuhan, virus There (corona in and COVID-19 2020. disease increased as March respiratory disease in had acute new byWHO anof this cases declaredpandemic named of of was cause (WHO) number the Organisation as The identified was China. coronavirus; novel a SARS-CoV-2; INTRODUCTION: 5,6,7 3,4 2 8,9,10,11 1,2 Posted on Authorea 15 Jun 2020 | The copyright holder is the author/funder. All rights reserved. No reuse without permission. | https://doi.org/10.22541/au.159225357.75853734 | This a preprint and has not been peer reviewed. Data may be preliminary. hthaigls nCVD1 sntbcueo h ffso ner ct ttso n nomn htcan that involment any or otitis acute ear, suggested in be effusion can the It findings findings. of CT bone because chest temporal without not or ear is with inner COVID-19 bone and temporal in tympano- ear on and loss effect middle test hearing no cells, hearing has that perform mastoid virus not the the did which that evaluating we found study, After we but patients. prospective patients. patients the to a all of the test design of all metric not membranes to tympanic could together the test we test examined hearing We contagious hearing of very and lack and tomography is groups bone COVID-19 study temporal the the performs of Because number patients. small and/or design, the otitis retrospective of investigated. were acute no were of study were signs our bone The There of temporal COVID-19. CT. Limitations CT. in in chest interestingly CT findings in temporal and temporal CT COVID-19 healthy the typical of findings investigate normal which and signs CT study typical effusion had first typical without the patients or No is All with study bone. Our grading ear. to temporal middle according in or groups involment two cells between specific mastoid difference air no in and found effusion ground-glass thickening, we no bilateral septal study or interlobular our unilateral enlargement, In like vascular CT without chest or disease. sign. in with the bronchogram signs of consolidation and spread radiological quarantine and the distancing, typical opacities preventing social has the hygiene, of pneumonia is hand points COVID-19 so there main COVID-19, But the for imaging. are treatment inner bone masks specific ear, temporal face no middle wearing by is effect detected there COVID-19. may be now of Virus may Untill imaging which infection. bone loss of temporal hearing route about cause important study and an no cells be radiological evidence. mastoid may and ear in or studies cavity more middle ear seen mastoid needs and SARS-CoV-2’s and be attention ear getting can about has Middle COVID-19 this unknown of pathogenesis and a loss coronaviruses hearing is Evaluating other There like cells. media radiological mastiod otitis in Effusion seen imaging. and cause infections. be tract might can ear effusion respiratory Virus This middle upper infections. involvement. and tract the respiratory media of upper otitis and findings acute examination media these otitis in acute of role in tube has Because seen eustachian coronaviruses often COVID-19. that evidence. ear, in known no involved Middle is is is COVID-19. It there which in but mucosa relation involved contaminated airway close is be by has mucosa might covered Nasopharynx Airway ear are nasopharynx. ear. cells and middle mastoid nose and and in cells concentrations mastoid high with in found virus of no SARS-CoV-2 any were in there observed and was system involvement grading 3). cavity DISCUSSION: our of (Table ear to symptoms (p=0,50) (p: middle according onset groups compared groups and and the were between 1) between cells chest (Table findings difference proportion air in diseases imaging female/male mastoid Temporal findings comorbid patients. obvious the no for the CT had groups No in chest 2 the 2). difference their between group (Table no patients, difference to disease were 26 no according There was included groups patients. There and two 0.636). 16 findings into CT included divided chest were and specific Patients CT had female. study. 1 were this Group (38.1%) to findings. 16 included and were deviation male scans computed (standard were CT temporal 45,61 was a cranial had age or and mean scans COVID-19 The axial for CT positive confirmed paranasal were scans, who (CT) obtained. patients tomography was hospitalized 42 consent of informed total and and A study Health the of about Ministry informed the were from patient RESULTS: taken All was approval commitee. ethical ethical subjects, local human the includes research this Because 6.13,14 18 ± 96;mnmx2–3yas.O h 2ptet,2 (61.9%) 26 patients, 42 the Of years). 20–83 min–max 19.60; 1,12,13 3 15,16,17 Posted on Authorea 15 Jun 2020 | The copyright holder is the author/funder. All rights reserved. No reuse without permission. | https://doi.org/10.22541/au.159225357.75853734 | This a preprint and has not been peer reviewed. Data may be preliminary. hr a omdl a rmsodivletas oeuinse nCVD1.Acrigt u findings our to According COVID-19. changes. in radiological seen References: bone effusion temporal no any also involment COVID-19. cause mastoid in doesn’t or loss SARS-CoV-2 ear hearing middle of no etiology was There the evaluate hearing to detailed useful populations, be larger will with CONCLUS evaluation studies Further ear findings. inner these and with cochlear CT tests, temporal via diagnosed be Uu ,Sv¸ .CetC etrso h oe ooaiu ies CVD1)[ulse online [published (COVID-19) disease coronavirus novel the of features CT Chest Sava¸s R. F, Ufuk 18. control for mask face of ¸Sim¸sek wearing S, community-wide 17. Yavuz of role J The Turk al. community. et in VW measures Chuang control SC, Wong and VC, Prevention Cheng COVID-19: 16. F. Aktas I, Hasanoglu R, Guner 15. 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Posted on Authorea 15 Jun 2020 | The copyright holder is the author/funder. All rights reserved. No reuse without permission. | https://doi.org/10.22541/au.159225357.75853734 | This a preprint and has not been peer reviewed. Data may be preliminary. the-temporal-bone-involment-in-covid-19 3.docx table file Hosted the-temporal-bone-involment-in-covid-19 2.docx table file Hosted the-temporal-bone-involment-in-covid-19 1.docx table file Hosted ha fpit 00My12]. May 2020 print, of ahead vial at available at available at available https://authorea.com/users/333418/articles/459637-investigation-of- https://authorea.com/users/333418/articles/459637-investigation-of- https://authorea.com/users/333418/articles/459637-investigation-of- ukJMdSci Med J Turk 001.96sg20-3.doi:10.3906/sag-2004-331. 2020;10.3906/sag-2004-331. . 5