Polyclonal Antibody to UBE4A (N-Term)

AP11964PU-N OriGene Technologies Inc. OriGene EU

Acris Antibodies GmbH 9620 Medical Center Drive, Ste 200 Schillerstr. 5 Rockville, MD 20850 32052 Herford UNITED STATES GERMANY Phone: +1-888-267-4436 Phone: +49-5221-34606-0 Fax: +1-301-340-8606 Fax: +49-5221-34606-11 [email protected] [email protected]

Polyclonal Antibody to UBE4A (N-term) - Purified Alternate names: KIAA0126, Ubiquitin conjugation factor E4 A Catalog No.: AP11964PU-N Quantity: 0.1 mg Concentration: 0.25 mg/ml Background: Ubiquitination requires a ubiquitin-activating enzyme, a ubiquitin-conjugating enzyme, and usually a substrate-specific ubiquitin-protein ligase. Multiubiquitination needs a fourth factor, to bind to the ubiquitin moieties of preformed conjugates and catalyze ubiquitin chain assembly in conjunction with the first three proteins.1 Human protein KIAA0126, with a predicted 1,073 amino acid residues, is a member of the novel protein family defined by ubiquitination conjugation factor E4.2 In yeast, E4 activity is linked to cell survival under stress conditions, indicating that eucaryotes use E4-dependent proteolysis pathways for multiple cellular functions. Uniprot ID: Q14139 NCBI: 5874 GeneID: 9354 Host / Isotype: Rabbit / Ig Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human UBE4A. Format: State: Liquid Ig fraction Purification: Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS Buffer System: PBS with 0.09% (W/V) sodium azide Applications: ELISA 1:1,000. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user. Specificity: This antibody detects UBE4A at N-term. Species: Human. Other species not tested. Add. Information: Molecular weight: 123537 Da Storage: Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. General Readings: 1. Nagase, T., et al., DNA Res. 2(4):167-174 (1995).

For research and in vitro use only. Not for diagnostic or therapeutic work. OG/20130513 Material Safety Datasheets are available at www.acris-antibodies.com or on request. Acris Antibodies is now part of the OriGene family. Learn more at www.origene.com 1 / 1