Human GPCR Expression List (n= 85) 2017/6/26 - No Official Symbol Official Full Name Aliases Gene ID ウイルスID A 1 ACRBP acrosin binding protein CT23, OY-TES-1, SP32 84519 V16C_101 2 ADORA2A A2aR, ADORA2, RDC8 135 V16C_102 3 ADORA2B ADORA2 136 V16C_103 4 AGTR1 angiotensin II receptor, type 1 AG2SB, AT1, AT1AR, AT1B, AT1BR, AT1R, AT2R1, HAT1R, AGTR1 185 V16C_104 5 AGTR2 angiotensin II receptor, type 2 AT2, ATGR2, MRX88 186 V16C_105 C 6 C3AR1 complement component 3a receptor 1 AZ3B, C3AR, HNFAG09 719 V16C_106 7 C5AR2 complement component 5a receptor 2 C5L2, GPF77, GPR77 27202 V16C_107 8 C5R1 complement component 5a receptor 1 C5A, C5AR, C5R1, CD88 728 V16C_108 9 CALCR CRT, CT-R, CTR, CTR1 799 V16C_109 10 CCKAR cholecystokinin A receptor CCK-A, CCK1-R, CCK1R, CCKRA 886 V16C_110 11 CCR1 chemokine (C-C motif) receptor 1 CD191, CKR-1, CKR1, CMKBR1, HM145, MIP1aR, SCYAR1 1230 V16C_111 12 CCR5 chemokine (C-C motif) receptor 5 CC-CKR-5, CCCKR5, CCR-5, CD195, CKR-5, CKR5, CMKBR5, 1234 V16C_112 13 CCR9 chemokine (C-C motif) receptor 9 CC-CKR-9, CDw199, GPR-9-6, GPR28 10803 V16C_113 14 CD97 CD97 molecule TM7LN1 976 V16C_114 15 CHRM1 cholinergic receptor, muscarinic 1 HM1, M1, M1R 1128 V16C_115 16 CX3CR1 chemokine (C-X3-C motif) receptor 1 CCRL1, CMKBRL1, CMKDR1, GPR13, GPRV28, V28 1524 V16C_116 C-C, C-C-CKR-1, CD128, CD181, CDw128a, CKR-1, CMKAR1, IL8R1, 17 CXCR1 chemokine (C-X-C motif) receptor 1 3577 V16C_117 IL8RA, IL8RBA 18 CXCR2 chemokine (C-X-C motif) receptor 2 CD182, CDw128b, CMKAR2, IL8R2, IL8RA, IL8RB 3579 V16C_118 19 CXCR6 chemokine (C-X-C motif) receptor 6 BONZO, CD186, STRL33, TYMSTR 10663 V16C_119 20 CYSLTR1 cysteinyl 1 CYSLT1, CYSLT1R, CYSLTR, HMTMF81 10800 V16C_120 D 21 DRD1 D1 DADRA, DRD1 1812 V16C_121 E 22 EDNRA type A ET-A, ETA, ETA-R, ETAR, ETRA, hET-AR 1909 V16C_122 RP11-318G21.1, ABCDS, ET-B, ET-BR, ETB, ETBR, ETRB, HSCR, 23 EDNRB endothelin receptor type B 1910 V16C_123 HSCR2, WS4A coagulation factor II (thrombin) F 24 F2RL2 PAR-3, PAR3 2151 V16C_124 receptor-like 2 25 FFAR3 3 FFA3R, GPR41 2865 V16C_125 26 FGFR1OP FGFR1 oncogene partner FOP 11116 V16C_126 27 FPR1 1 FMLP, FPR 2357 V16C_127 28 FPR2 formyl peptide receptor 2 ALXR, FMLP-R-II, FMLPXA, FPRH1, FPRH2, FPRL1, HM63, LXA4R, 2358 V16C_128 29 FZD4 class receptor 4 CD344, EVR1, FEVRS, Fz-4, Fz4, FzE4, GPCR, hFz4, FZD4 8322 V16C_129 30 FZD6 frizzled class receptor 6 FZ-6, FZ6, HFZ6, NDNC10 8323 V16C_130 31 FZD7 frizzled class receptor 7 FzE3 8324 V16C_131 G 32 GLP2R glucagon-like peptide 2 receptor 9340 V16C_132 33 GPBAR1 G protein-coupled bile acid receptor 1 BG37, GPCR19, GPR131, M-BAR, TGR5 151306 V16C_133

1 PRO3GPCR-201706(Ⅲ) Human GPCR Expression List (n= 85) 2017/6/26 - No Official Symbol Official Full Name Aliases Gene ID ウイルスID G protein-coupled estrogen receptor CEPR, CMKRL2, DRY12, FEG-1, GPCR-Br, GPER, GPR30, LERGU, 34 GPER1 2852 V16C_134 1 LERGU2, LyGPR, mER 35 GPR12 G protein-coupled receptor 12 GPCR12, GPCR21, PPP1R84 2835 V16C_135 36 GPR137B G protein-coupled receptor 137B RP5-985L19.1, TM7SF1 7107 V16C_136 37 GPR146 G protein-coupled receptor 146 PGR8 115330 V16C_137 38 GPR15 G protein-coupled receptor 15 BOB 2838 V16C_138 39 GPR155 G protein-coupled receptor 155 DEP.7, DEPDC3, PGR22 151556 V16C_139 40 GPR17 G protein-coupled receptor 17 2840 V16C_140 41 GPR171 G protein-coupled receptor 171 H963 29909 V16C_141 42 GPR173 G protein-coupled receptor 173 RP1-290F12.1, SREB3 54328 V16C_142 43 GPR18 G protein-coupled receptor 18 RP11-461N23.8 2841 V16C_143 44 GPR182 G protein-coupled receptor 182 7TMR, ADMR, AM-R, AMR, G10D, gamrh, hrhAMR 11318 V16C_144 45 GPR3 G protein-coupled receptor 3 ACCA 2827 V16C_145 46 GPR39 G protein-coupled receptor 39 2863 V16C_146 47 GPR55 G protein-coupled receptor 155 LPIR1 9290 V16C_147 48 GPR63 G protein-coupled receptor 63 PSP24(beta), PSP24B 81491 V16C_148 49 GPR82 G protein-coupled receptor 82 RP11-204C16.5 27197 V16C_149 50 GPR84 G protein-coupled receptor 84 EX33, GPCR4 53831 V16C_150 51 GPR85 G protein-coupled receptor 85 SREB, SREB2 54329 V16C_151 52 GRPR gastrin-releasing peptide receptor BB2 2925 V16C_152 H 53 HCAR1 hydroxycarboxylic acid receptor 1 FKSG80, GPR104, GPR81, HCA1, LACR1, TA-GPCR, TAGPCR 27198 V16C_153 54 HCAR2 hydroxycarboxylic acid receptor 2 GPR109A, HCA2, HM74a, HM74b, NIACR1, PUMAG, Puma-g 338442 V16C_154 55 HCAR3 hydroxycarboxylic acid receptor 3 GPR109B, HCA3, HM74, PUMAG, Puma-g 8843 V16C_155 56 HCRTR2 hypocretin (orexin) receptor 2 OX2R 3062 V16C_156 5-hydroxytryptamine (serotonin) 57 HTR1D 5-HT1D, HT1DAA, HTRL, RDC4, HTR1D 3352 V16C_157 receptor 1D, G protein-coupled 5-hydroxytryptamine (serotonin) 58 HTR2A RP11-147L20.2, 5-HT2A, HTR2 3356 V16C_158 receptor 2A, G protein-coupled 5-hydroxytryptamine (serotonin) 59 HTR2B 5-HT(2B), 5-HT2B 3357 V16C_159 receptor 2B leucine-rich repeat containing G L 60 LGR6 RP11-572A16.3, GPCR, VTS20631 59352 V16C_160 protein-coupled receptor 6 61 LPAR4 receptor 4 GPR23, LPA4, P2RY9, P2Y5-LIKE, P2Y9 2846 V16C_161 M 62 MC4R 4160 V16C_162 melanin-concentrating hormone 63 MCHR1 CTA-229A8.4, GPR24, MCH-1R, MCH1R, SLC-1, SLC1 2847 V16C_163 receptor 1 N 64 NMUR2 2 FM-4, FM4, NMU-R2, NMU2R, TGR-1, TGR1 56923 V16C_164

2 PRO3GPCR-201706(Ⅲ) Human GPCR Expression List (n= 85) 2017/6/26 - No Official Symbol Official Full Name Aliases Gene ID ウイルスID 65 NPY1R Y1 NPY1-R, NPYR 4886 V16C_165 O 66 OPRK1 , kappa 1 K-OR-1, KOR, KOR-1, OPRK 4986 V16C_166 , family 51, 67 OR51E2 hCG_2044604, OR51E3P, OR52A2, PSGR 81285 V16C_167 subfamily E, member 2 olfactory receptor, family 7, subfamily 68 OR7A5 HTPCR2 26659 V16C_168 A, member 5 oxoglutarate (alpha-ketoglutarate) 69 OXGR1 GPR80, GPR99, P2RY15, P2Y15, aKGR 27199 V16C_169 receptor 1 P2Y, G-protein P 70 P2RY1 P2Y1 5028 V16C_170 coupled, 1 purinergic receptor P2Y, G-protein 71 P2RY10 RP3-333E23.1, LYPSR2, P2Y10 27334 V16C_171 coupled, 10 purinergic receptor P2Y, G-protein 72 P2RY11 P2Y11 5032 V16C_172 coupled, 11 purinergic receptor P2Y, G-protein 73 P2RY14 BPR105, GPR105, P2Y14 9934 V16C_173 coupled, 14 pyrimidinergic receptor P2Y, G- 74 P2RY6 PP2891, P2Y6 5031 V16C_174 protein coupled, 6 75 PTAFR Platelet-activating factor receptor PAFR 5724 V16C_175 76 PTGDR prostaglandin D2 receptor (DP) AS1, ASRT1, DP, DP11, PTGDR 5729 V16C_176 R 77 RGR retinal G protein coupled receptor RP44 5995 V16C_177 S 78 S1PR1 sphingosine-1-phosphate receptor 1 CD363, CHEDG1, D1S3362, ECGF1, EDG-1, EDG1, S1P1 1901 V16C_178 79 S1PR3 sphingosine-1-phosphate receptor 3 EDG-3, EDG3, LPB3, S1P3 1903 V16C_179 80 S1PR4 sphingosine-1-phosphate receptor 4 EDG6, LPC1, S1P4, SLP4 8698 V16C_180 81 SSTR1 1 SRIF-2, SS-1-R, SS1-R, SS1R 6751 V16C_181 T 82 TMEM11 transmembrane protein 11 PM1, PMI, C17orf35 8834 V16C_182 vasoactive intestinal peptide receptor HVR1, II, PACAP-R-2, PACAP-R2, RDC1, V1RG, VAPC1, VIP-R-1, V 83 VIPR1 7433 V16C_183 1 VIPR, VIRG, VPAC1, VPAC1R, VPCAP1R vasoactive intestinal peptide receptor tcag7.561, C16DUPq36.3, DUP7q36.3, PACAP-R-3, PACAP-R3, VIP-R- 84 VIPR2 7434 V16C_184 2 2, VPAC2, VPAC2R, VPCAP2R X 85 XCR1 chemokine (C motif) receptor 1 CCXCR1, GPR5 2829 V16C_185

3 PRO3GPCR-201706(Ⅲ)