Govind S et al / Int. J. of Pharmacy and Analytical Research Vol-7(2) 2018 [218-225]

ISSN:2320-2831

IJPAR |Vol.7 | Issue 2 | Apr - Jun -2018 Journal Home page: www.ijpar.com

Research article Open Access

MASS GAINER POWDER; Helps to increase muscle mass, reduce body fat increases strength & Keeping muscles healthy and optimising their repair to maximise performance Govind Shukla, Neha S.Giri, D. Sruthi Rao, C.J. Sampath Kumar Lactonova Nutripharm (P) Ltd, Makers of MASS GAINER POWDER 81/3, IDA Mallapur, Hyderabad, Telangana, India-500 076. *Corresponding Author: Govind Shukla

ABSTRACT Keeping muscles healthy and optimising their repair after training is extremely important in sport to maximise performance. For many sports, it is also desirable to increase muscle mass, reduce body fat overall and increase strength where necessary. This review summarises the current available scientific literature regarding the effect of MASS GAINER POWDER; Helps to increase muscle mass, reduce body fat increases strength & Keeping muscles healthy and optimising their repair to maximise performance. Keywords: MASS GAINER POWDER, Muscle mass, Strength

INTRODUCTION When this additional stress on the muscle is combined with recovery time and optimal , How to gain muscle mass? the muscle will repair, strengthen and ultimately Gaining lean body mass involves a combination grow in size. of strength training, which acts as a stimulus for muscle growth, and a balanced diet, which provides Progression the energy and nutrients to grow at the optimal rate. You must continue to increase the weight or for an athlete it is best to modify his body number of repetitions to increase your resistance composition outside of competition season. and continue gains from overloading your muscles. Training programme Goal Overload Your muscles need to bentrained specifically for the outcome you desire. If endurance gains are You need to load your muscles with your target, then lower weights with higher weights/resistance greater than they are used to. repetitions are important; for higher maximal

www.ijpar.com ~218~ Govind S et al / Int. J. of Pharmacy and Analytical Research Vol-7(2) 2018 [218-225] strength training, aim for fewer repetitions but a Eat and drink frequently greater weight load. Aim to eat every 2-3 hours. This will allow you

to increase your food and kJ intake without feeling HOW TO KEEP MUSCLES HEALTHY overly full. Easy snacks between meals include smoothies, milkshakes, cereal/muesli bars, low fat Positive energy balance to build muscle yoghurt, tuna on crackers, breakfast cereal and low This means having more kilojoules (kJ) each fat milk or sports bars. day than you would normally require; an extra Refuel as soon as possible after training. 2000-4000kJ is ideal.It is however important to remember that these kJs need to come from GOOD A carbohydrate and rich snack needs to quality food and drinks, and it’s not an opportunity be eaten ASAP after training to maximise muscle to eat junk food or overindulge in high fat, salt or repair and recovery. Alcohol should be completely sugary options. avoided at this time as it will compromise muscle recovery. Carbohydrate intake Be patient Ideally base all meals and snacks on carbohydrate rich foods. Also include plenty of Increases in body mass of 2-4 kg per month are fruit and vegetables each day. Having fruit juice or considered achievable but will depend on how you low fat milk with meals can help increase your respond individually to strength training. Muscle daily kJ intake. Consuming adequate carbohydrate gains will not happen overnight though, so be is extremely important to ensure that protein is not patient. There will be a limit to the increase in used to fuel a workout. muscle mass over time. Adequate protein intake How mass gainer powder helps to increase muscle mass Aim for between 1.2-1.8g protein per kg of body weight, depending on your training/stage of Everyday food is inadequate to provide you life. Include protein rich foods in all your meals with the nutrition you need to maximise muscle and snacks e.g. lean meat, skinless chicken, eggs, growth. MASS GAINER POWDER is quick and fish and milk products. For optimal muscle convenient way to include protein before or after recovery after a strength training workout it is ideal strength training workout. It is best to seek to have between 20-25g protein straight after, along individual advice from a sports nutritionist or with some carbohydrate. Despite the focus on dietitian when it comes to protein supplements or protein, having more than you need will NOT any other supplements for that matter. increase strength or size gains and is unnecessary.

Composition of mass gainer powder 2g Oat & wheat Sugars 20g added sugar Steviol glycosides 0.15gm Protein 9gm Whey protein concentrate Calcium 600mg Tri calcium phosphate Phosphorous 500mg Tri calcium phosphate 5mg Ferrous Bisglycinate Sodium 300mg Sodium sulphate Potassium 300mg Potassium phosphate 2mg Manganese sulphate Copper 1mg Copper Sulphate 20mcg Sodium Selenite

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Magnesium 300mg sulphate A 0.6mg Retinal palmitate 30mg Ascorbic acid 0.35mg Ergocalciferol 14.9mg DL Tocopherol Acetate Vitamin B1 1mg Thiamine Mononitrate Vitamin B2 1mg Riboflavin Vitamin B3 10mg Niacinamide Vitamin B5 6mg Pantothenic acid Vitamin B6 2mg Pyridoxine HCl Vitamin B9 130mcg Folic acid 100mg Zinc Sulphate Panex 0.01g L--L-tartrate 10mg L- Carnitine L-Tartate

Role of whey protein concentrate in mass whey protein more effective than other for gainer powder repairing exercise-related muscle damage and Whey and whey components offer several building bigger, stronger muscles. Its consumption benefits for individuals with physically active results in a higher peak amino acid concentration in lifestyles [1]. Whey protein is a rich source of the blood than other proteins [4]. Whey proteins are branched chain amino acids (BCAAs), containing rich in the amino acids, arginine and lysine, which the highest known levels of any natural food may increase the release of growth hormone, a source. BCAAs are important for athletes since stimulator of muscle growth. Whey protein cans unlike the other essential amino acids, they are showing an increase in lean muscle fiber metabolized directly into muscle tissue and these adaptations [5]. Milk protein is better than soy protein are the first ones used during periods of exercise for greater gains in lean mass and greater muscle and resistance training. Whey protein provides the hypertrophy. 20 g of whey protein casein switches net body with BCAAs to replenish decreased levels and amino acid balance to positive after ingestion. It start repairing and rebuilding lean muscle tissue. influences muscular power and strength and increase Essential amino acids and whey protein are equally intracellular glutathione. It increases net protein gain. effective in stimulating muscle protein synthesis in The rate of protein digestion affects protein gain elderly individuals [2]. These amino acids provide an differently during aging in humans. Whey protein is energy source during endurance exercise which digested faster than casein. Faster digestion gives rise allows athletes to train more intensively for longer to a quicker amino acid flood into muscle cells. Whey periods of time [3]. Moreover, whey protein is an protein is the preferred protein for net protein gain excellent source of the , leucine. [6]. Dietary protein and resistance training affect Leucine is important for athletes as it plays a key role muscle body composition in older persons. Adequate in promoting muscle protein synthesis and muscle intake of protein combats sarcopenia. Resistance growth. Research has shown that individuals who training helps older people gain muscle, hypertrophy exercise benefit from diets high in leucine and have muscle, and increase whole body fat-free mass. more lean muscle tissue and less body fat compared to Adequate intake of protein and resistant exercise individuals whose diet contains lower levels of synergistically can reduce sarcopenia [7]. leucine. Whey protein is easy to digest protein and is Weight management efficiently absorbed into the body. It is often referred Studies show that achieving and maintaining a to as a ―fast‖ protein for its ability to quickly provide healthy weight can add years to life and help nourishment to muscles . Indeed, its consumption has prevent weight related complications, including been shown to result in faster muscle protein diabetes, cancer and heart disease. Diet plays a key synthesis as compared to other proteins. This makes

www.ijpar.com ~220~ Govind S et al / Int. J. of Pharmacy and Analytical Research Vol-7(2) 2018 [218-225] role in any weight management program and in bone disorders such as osteoporosis and possibly an adding whey protein often helps make a positive important physiological regulator of bone growth difference. Whey protein is a good choice for [17]. Glycomacropeptide has shown inhibitory diabetics who need to carefully manage food activity to enamel demineralization and promotes intake. It has potential as an added component in tooth enamel remineralization. Some whey dietary plans and in functional foods aimed at components (e.g., proteose-peptones) may protect control of appetite and body weight and in the against tooth tissue demineralization, and other whey management of the metabolic consequences of components, because of their immunostimulatory excess body fat. It has potential as physiologically effects, may have favorable effects on dental plaque functional food component for persons with obesity [18]. and its co-morbidities (hypertension, type II diabetes, Role of in mass gainer powder hyper-and dislipidemia) [8]. It is the best protein for fat loss during energy restricted diets, when combined For the elite athlete’s performance, vitamins are with exercise [9]. It improves body composition and essential. In fact, an athlete’s performance will reduces waist circumference. The researchers found drop considerably if certain vitamins are deficient that individuals who consumed whey protein weighed in his or her diet. Vitamins are unique in that they are less, had less body fat [10]. Whey protein is the best absorbed directly into the blood. Because of this protein for fat loss during energy restricted diets. It factor, they are able to move freely throughout the influences on appetite and hunger controlling body, and once they reach the cell, they can circulate hormones [11]. A high-protein diet reduces energy inside its water-filled compartments. intake and adiposity and that whey protein is more Since vitamins are extremely mobile, they are effective than red meat in reducing body weight gain also easily excreted from the body. The kidney, and increasing insulin sensitivity [12]. In addition, whose function is to monitor the blood that flows whey protein helps control blood glucose levels and through it, detects excess amounts of water-soluble has been shown to be beneficial for weight vitamins and properly disposes of them. In cases of management, both of which are often a concern for extreme excess, which is usually due to improper type-II diabetics. The meal with α-lactalbumin supplementation, there will be certain side effects preserves lipid oxidation and rapidly delivers amino that may become severe. acids for use during exercise improved the efficiency The are the most crucial water- of exercise training to decrease adiposity [13]. soluble vitamins that aid in the overall performance of the athlete. While vitamins in general do not Bone health yield energy like the macronutrients, the B vitamins Milk contains several components effective for actually assist in the utilization of that energy. The bone health. Milk basic protein promotes bone B vitamins thiamine, riboflavin, niacin, pantothenic formation and suppresses bone resorption in acid, and biotin are all units of compounds called healthy adult men. Milk basic protein is in the coenzymes. Coenzymes are small organic whey protein fraction. 300 mg of milk basic protein molecules that are closely associated with certain increases serum osteocalcin concentrations. Milk enzymes, and that aid in their function. Coenzymes basic protein promotes bone formation and are so important that the enzymes cannot function at suppresses bone resorption [14]. The milk basic all without their presence. The other B vitamins protein of whey is the active protein that activates assists enzymes that metabolize amino acids, while osteoblast. The active component in the whey helps in the multiplication of cells. protein plays an important role in bone formation Role of minerals in mass gainer powder by activating osteoblasts [15]. LF is a potent regulator of bone cell activity and Minerals are the other group of micronutrients increases bone formation in vivo. It increases the body requires. They are in a completely osteoblast differentiation and forms new bone different class from the other micronutrients for formation. It also decreases bone breakdown [16]. several key reasons, including each ’s It has powerful anabolic, differentiating and anti- chemical makeup, their availability through apoptotic effects on osteoblasts, and inhibits absorption from food, the interactions that take osteoclastogenesis. It is a potential therapeutic target place between two or more minerals, and their roles

www.ijpar.com ~221~ Govind S et al / Int. J. of Pharmacy and Analytical Research Vol-7(2) 2018 [218-225] in the body. Since minerals are a dynamic factor in strength because it enhances the body’s own a person’s performance. creatine production. A 2010 study by Chinese Vitamins are carbon based and are therefore are researchers found that mice that were fed ginseng organic compounds. Anything that is carbon based for 15 days experienced less fatigue during forced can be easily destroyed by heat, radiation, and most swimming. The researchers discovered that one of significantly, time. Minerals, on the other hand, the main ways that ginseng blunted fatigue in the never change in chemical makeup. They never mice was by increasing levels of enzymes involved undergo a change to another chemical compound in creatine production. This allowed them to have such as we see in the conversion of retinol to more quick energy and burn fewer carbohydrates. retinoic acid. However, they can combine with Greater levels of the kind of quick energy creatine another compound for a specific function, such as promotes can lead to more strength in the gym, as the iron in hemoglobin and myoglobin serves to well as muscle growth. transport and store oxygen. In athletic circles, ginseng is best known for its The absorption and transportation processes of ability to boost muscle endurance. One study from minerals by the body are a lot like vitamins in the Germany reported that trained athletes sense that some minerals, like potassium, are easily taking Panax ginseng experienced significant absorbed, transported, and excreted by the kidneys, improvements in their aerobic capacity. A study and others are not. Calcium is much like a fat- from California State Polytechnic University soluble vitamin in the sense that it needs assistance reported that subjects taking Panax notoginseng for in the form of carriers and transporters for proper 30 days increased their exercise time to exhaustion utilization. Since minerals can behave like vitamins by more than seven minutes. Canadian researchers in terms of absorption, storage, and excretion, there reported that rats receiving ginseng for just four is the possibility that an excess of certain minerals days increased their exercise time to exhaustion can lead to toxicity. because ginseng causes the body to spare glucose The bioavailability of the particular minerals present and burn more fat for fuel. This not only explains in food can vary. Bioavailability refers to the amount why ginseng increases muscle endurance but also of the particular nutrient that is available for why it can aid fat loss. absorption by the body. Some foods contain Ginseng also may delay fatigue by directly compounds called binders that actually hold on to the affecting the brain. Korean researchers found that mineral and prevent it from being absorbed. For rats given ginseng before exercise showed example, the compound known as phytic acid increased time to exhaustion for treadmill running (phytates) in legumes, grains, split peas, and parsnips because of lower serotonin production from can act in this manner. In foods like spinach, rhubarb, tryptophan in the brain. Serotonin signals fatigue, plums, blueberries, nuts, and seeds, oxalates reduce which reduces muscle strength and endurance. By the amount of minerals available for absorption. inhibiting serotonin production, you can train Although all of these foods provide great health stronger for longer. benefits, the bioavailability of the minerals they Spanish researchers, on the other hand, contain will be low. To lessen this disadvantage, an discovered that rats given ginseng for 12 weeks athlete desiring adequate amounts of minerals would experienced higher mitochondria numbers and follow the diet-planning. greater blood-vessel density in their muscles. This means that ginseng may enhance endurance by Role of Panax ginseng in mass gainer powder getting more nutrients and oxygen from the blood Boosts Physical Performance into the muscles. With more mitochondria, muscles Several studies have reported that ginseng can are better equipped to convert those nutrients and help boost physical performance. Although most of oxygen into fuel. Italian scientists reported that these studies were concerned with muscle trained subjects taking ginseng for six weeks endurance, one study reported that male and female increased their aerobic performance through subjects taking 1 gram of Panax ginseng every day increased oxygen consumption. This may have for six weeks increased muscle strength in the been a result of greater blood-vessel density, as upper and lower body. Ginseng may increase reported in the Spanish study. Or it may be because of a boost in nitric-oxide levels, which ginseng has

www.ijpar.com ~222~ Govind S et al / Int. J. of Pharmacy and Analytical Research Vol-7(2) 2018 [218-225] been shown to provoke by increasing activity of the Role of L-carnitine in mass gainer powder enzyme that converts arginine into NO in the body. Athletic performance and L-Carnitine Having higher NO levels during workouts means that ginseng not only will increase your endurance Carbohydrates are the primary source of energy. but also will boost your muscle size and strength There’s a reason why athletes are recommended to gains, as research confirms. do carb loading few days before competition. Marathon runners typically eat pastas and grain a Aids muscle recovery week before the actual event to have sufficient fuel In addition to aiding workout performance, for miles and miles. Eating complex carbohydrates ginseng can aid muscle recovery after the workout gives you the necessary fuel that you can use is over, which also encourages greater gains in during intense activities. muscle mass. Spanish scientists found that rats that What carnitine does is to provide an additional were fed Panax ginseng after completing a bout of source of energy into the equation. It converts fats downhill running — exercise that for rats is the into energy in cellular level. By taking carnitine equivalent to doing negative reps and is known to from food and supplements, athletes can also rely cause muscle damage — had significantly less not only on their carbohydrates but also on their damage to their thigh muscles and reduced body fat as fuel. This gives you an additional boost inflammation. Korean researchers also reported that of energy in order to perform on your sport. male college students taking ginseng for one week Anti-catabolic effect experienced less thigh-muscle damage and inflammation after an intense uphill running test as One of the reasons carnitine is popular among compared to those receiving a placebo. This athletes is the fact that it has an anti-catabolic allowed the subjects taking ginseng to maintain effect. According to research, the amount of higher insulin sensitivity after the workout, which carnitine in a person’s system is related to the could further enhance recovery and muscle growth amount of glycogen found in the muscles. What because insulin is an anabolic hormone. Chinese muscle carnitine does is to prevent the use of researchers reported similar findings in male glycogen in the muscles. With this glycogen sparing college students following four weeks of ginseng effect, it becomes an anti-catabolic agent that athletes supplementation. could benefit from. Another group of Korean researchers found that Recovery eight weeks of Panax ginseng supplementation in men decreased exercise-induced oxidative damage Aside from the fact that it gives the athlete by increasing free-radical scavenging. This not additional source of energy especially during only helped prolong their exercise time to stressful situations, it has also been reported that L- exhaustion but also aided their ability to recover carnitine comes in handy in helping the body from the workout. Similar results also were recover. reported in animal studies. After an intensive exercise, expect a drop in Ginseng not only protects muscles from serum pH levels. It also follows that there’s an oxidative damage following aerobic exercise but increase in lactic acid concentration in the body. also appears to protect the muscles from What L-carnitine does is to prevent damage in the mechanical damage, like the kind that weightlifting cellular level especially when you are dealing with can produce. Brazilian researchers have reported in hypoxic conditions during strenuous physical several studies that ginseng supplementation activity. What carnitine does is to lessen the protects the muscle fibers from damage during amount of lactic acid in the body post exercise. eccentric exercise (negative-rep training). They It decreases the amount of the anaerobic discovered that ginseng better protects membrane enzyme called PFK which then reduce the rate of integrity and decreases the accompanying oxidative glycolysis. With reduced rate of glycolysis, there’s damage. This can result in better muscle recovery fewer pyruvate molecule present which can create and growth. lactate.

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SUMMARY & CONCLUSION Administration Keeping muscles healthy and optimising their Taken by oral route at any time with food. repair after training is extremely important in sport Precautions to maximise performance. For many sports, it is also desirable to increase muscle mass, reduce body Food Supplements must not be used as a fat overall and increase strength where necessary. substitute for a varied and balanced diet and a MASS GAINER POWDER helps to increase healthy lifestyle. This Product is not intended to muscle mass, reduce body fat increases strength & diagnose, treat, cure or prevent any diseases. Do Keeping muscles healthy and optimising their not exceed the recommended daily dose. repair to maximise performance. Warnings

If you are taking any prescribed medication or SUPPLEMENT FACTS has any medical conditions always consults doctor Presentation: POWDER or health care practitioner before taking this supplement. Usage Side Effects MASS GAINER POWDER helps to increase muscle mass, reduce body fat increases strength & Mild side effects like nausea, headache and Keeping muscles healthy and optimising their vomiting in some individuals have been reported. repair to maximise performance. Storage: Store in a cool, dry and dark place. Contra-indications FAQs Product is contra-indicated in persons with Is the whey protein concentrate in mass gainer free Known hypersensitivity to any component of the of hormones? product hypersensitivity to any component of the Yes. The dairy for our whey protein concentrate product. comes from cows not treated with hormones. If I'm sensitive to lactose or dairy, is whey Recommended usage protein concentrate in mass gainer is the best Once or twice a day along with portion protein source for me? controlled nutritious meals and exercise. One Even though whey protein is traditionally low in Serving (30g- 1 Scoop) per day. ―Do not exceed lactose, people who are lactose intolerant and/or the recommended daily dose‖. have dairy sensitivity should consider using our Vegan Protein or Aminos to avoid any digestive Directions for Use distress (gas and/or bloating). Take one level scoop (30g) with skimmed How does mass gainer taste? milkor water to make a cup of 200ml. Gently shake well in shaker or stir well until the powder is Mass gainer tastes great, but everyone is evenly dispersed and drink immediately. different when it comes to taste.

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