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2021 Equine Prohibited Substances List - BANNED SUBSTANCES . Prohibited Substances include any other substance with a similar chemical structure or similar biological effect(s). . Prohibited Substances that are identified as Specified Substances in the List below should not in any way be considered less important or less dangerous than other Prohibited Substances. Rather, they are simply substances which are more likely to have been ingested by Horses for a purpose other than the enhancement of sport performance, for example, through a contaminated food substance.

SUBSTANCE ACTIVITY

1- Anabolic 3β-Hydroxy-5α-androstan-17-one Anabolic 4-chlorometatandienone Anabolic 5α-Androst-2-ene-17one Anabolic 5α--3α, 17α-diol Anabolic 5α-Androstane-3α, 17β-diol Anabolic 5α-Androstane-3β, 17α-diol Anabolic 5α-Androstane-3β, 17β-diol Anabolic 5β-Androstane-3α, 17β-diol Anabolic 7α-Hydroxy-DHEA Anabolic 7β-Hydroxy-DHEA Anabolic 7-Keto-DHEA Anabolic 17-Alpha-Hydroxy MALES Anabolic 19-Norandrosterone Anabolic 19-Noretiocholanolone Anabolic 20-Hydroxyecdysone Anabolic Δ1- Anabolic Non-steroidal anti-inflammatory Acenocoumarol Anticoagulant Acetanilid / Pancreatic Acetophenetidin () Analgesic Acetylmorphine Adiphenine Stimulant

1 December 2020 - Lausanne, Switzerland 2021 Equine Prohibited Substances List - BANNED SUBSTANCES . Prohibited Substances include any other substance with a similar chemical structure or similar biological effect(s). . Prohibited Substances that are identified as Specified Substances in the List below should not in any way be considered less important or less dangerous than other Prohibited Substances. Rather, they are simply substances which are more likely to have been ingested by Horses for a purpose other than the enhancement of sport performance, for example, through a contaminated food substance. Haemostatic AICAR Anabolic Non-steroidal anti-inflammatory drug Alcuronium Alendronate Bisphosphonates Narcotic oxidase inhibitor (anti-hyperuricaemia)

Almotriptan 5-hydroxatryptamine (antimigraine) Alphadolone acetate Alphaprodine analgesic Anxiolytic Anxiolytic Beta blocker Althesin IV anaesthetic Althiazide Alverine Antispasmodic Ambenonium inhibition Ambucetamide Antispasmodic Stimulant Stimulant Vasoconstrictor Diuretic Aminoglutehthamide inhibitor Aminoheptane Vasopressor Aminomethylbenzoic Anti-fibrinolytic Aminopicoline synthase inhibitor Aminopromazine Antispasmodic Immunosuppressant Stimulant

1 December 2020 - Lausanne, Switzerland 2021 Equine Prohibited Substances List - BANNED SUBSTANCES . Prohibited Substances include any other substance with a similar chemical structure or similar biological effect(s). . Prohibited Substances that are identified as Specified Substances in the List below should not in any way be considered less important or less dangerous than other Prohibited Substances. Rather, they are simply substances which are more likely to have been ingested by Horses for a purpose other than the enhancement of sport performance, for example, through a contaminated food substance. Amisometradine Diuretic Antipsychotic Amitriptylline Antihypertensive Ammonium Chloride () Acidifying agent Ammonium Sulphate Nerve-blocking agent Ammonium Sulphide Nerve-blocking agent Amodiaquine Antimalarial Amopyroquine Antimalarial Tricyclic antidepressant Antipsychotic Stimulant Amphetaminil Stimulant Non-steroidal anti-inflammatory drug Vasodilator Amyl nitrate/nitrite treatment Local anaesthetic Anabolic Anabolic Selective Modulator Anabolic Anabolic Anabolic Androsterone Anabolic Anileridrine Opioid analgesic Central Nervous System stimulant Anisindione Anticoagulant Anisotropine Antipyrine Non-steroidal anti-inflammatory drug Apazone () Non-steroidal anti-inflammatory drug Apocodeine Opioid analgesic

1 December 2020 - Lausanne, Switzerland 2021 Equine Prohibited Substances List - BANNED SUBSTANCES . Prohibited Substances include any other substance with a similar chemical structure or similar biological effect(s). . Prohibited Substances that are identified as Specified Substances in the List below should not in any way be considered less important or less dangerous than other Prohibited Substances. Rather, they are simply substances which are more likely to have been ingested by Horses for a purpose other than the enhancement of sport performance, for example, through a contaminated food substance. Opioid analgesic Anti-arrhythmic Sedative Apronalide Sedative Stimulant Argon Hypoxia Inducible Factor (HIF) Activator Arsenic Stimulant/toxic Local anaesthetic Beta blocker Selective noradrenaline re-uptake inhibitor Atracurium Muscle relaxant Azacyclonal Antipsychotic Sedative Azapetine Vasodilator Azapropazone (Apazone) Non-steroidal anti-inflammatory drug Immunosuppressant Diuretic Antispasmodic Bronchodilator Bronchodilator Sedative Sedative Stimulant Anticholinergic Benapryzine Anticholinergic Benazepril Antihypertensive Bendroflumethazide Diuretic Non-steroidal anti-inflammatory drug Non-steroidal anti-inflammatory drug Benoxinate Local anaesthetic Antipsychotic Anxiolytic

1 December 2020 - Lausanne, Switzerland 2021 Equine Prohibited Substances List - BANNED SUBSTANCES . Prohibited Substances include any other substance with a similar chemical structure or similar biological effect(s). . Prohibited Substances that are identified as Specified Substances in the List below should not in any way be considered less important or less dangerous than other Prohibited Substances. Rather, they are simply substances which are more likely to have been ingested by Horses for a purpose other than the enhancement of sport performance, for example, through a contaminated food substance. Sedative Benzonatate Antitussive Benzoylecgonine Stimulant/ metabolite Stimulant Benzthiazide Diuretic Benztropine Anticholinergic Stimulant Betaprodine Opioid analgesic Beta blocker Antihypertensive Anticholinergic Biphenamine Non-steroidal anti-inflammatory drug Biriperone Antipsychotic Beta blocker Bronchodilator Anabolic Anabolic Anabolic. Threshold substance: 0.015 micrograms free and conjugated boldenone per millilitre in from male Horses (other than geldings).

Boldione Anabolic Anti-arrhythmic Occular antihypertensive Bromantan Stimulant Anxiolytic Non-steroidal anti-inflammatory drug Bromisovalum Sedative agonist Bromophenethylamine Psychedelic Antipsychotic Anxiolytic

1 December 2020 - Lausanne, Switzerland 2021 Equine Prohibited Substances List - BANNED SUBSTANCES . Prohibited Substances include any other substance with a similar chemical structure or similar biological effect(s). . Prohibited Substances that are identified as Specified Substances in the List below should not in any way be considered less important or less dangerous than other Prohibited Substances. Rather, they are simply substances which are more likely to have been ingested by Horses for a purpose other than the enhancement of sport performance, for example, through a contaminated food substance. Analgesic/antipyretic Non-steroidal anti-inflammatory drug Vasoactive agent Bufotenine (Specified Substance) Naturally occurring Diuretic Beta antagonist Bunolol Beta blocker (Nylidrin) Sympathomimetic Beta blocker Antidepressant Anxiolytic Sedative Local anaesthetic Sedative Nerve blocker Local anaesthetic Antipsychotic Butoctamide release stimulation Beta blocker Butoxycaine Local anaesthetic Analeptic Anabolic Anxiolytic Candesartan Antihypertensive Natural , synthetic Psychotropic (Specified Substance) cannabinoids and other cannabimimetics Diuretic Topical analgesic/irritant Anxiolytic Anticholinergic Beta blocker Parasympathomimetic Carbazochrome Haemostatic

1 December 2020 - Lausanne, Switzerland 2021 Equine Prohibited Substances List - BANNED SUBSTANCES . Prohibited Substances include any other substance with a similar chemical structure or similar biological effect(s). . Prohibited Substances that are identified as Specified Substances in the List below should not in any way be considered less important or less dangerous than other Prohibited Substances. Rather, they are simply substances which are more likely to have been ingested by Horses for a purpose other than the enhancement of sport performance, for example, through a contaminated food substance. Carbetapentane () Antitussive Carbidopa Di hydroxythenylalanine decarboxylase inhibitor Carbimazole Antihyperthyroidism Carbocysteine Mucoactive Sedative Bronchodilator Opioid analgesic Muscle relaxant Carphedon () Stimulant Carphenazine Antipsychotic Anxiolytic Beta blocker Carticaine Local anaesthetic Beta blocker (Norpseudoephedrine) Stimulant Non-steroidal anti-inflammatory drug Beta blocker Cephaeline Emetic betaine Sedative Sedative Chloralbutanol Topical analgesic Anxiolytic Diuretic Chlormethiazole Sedative Anxiolytic Sedative Chlorophenesin Muscle relaxant Chlorophenyl Psychoactive Local anaesthetic Chloroquine Antimalarial Antipruritic Stimulant

1 December 2020 - Lausanne, Switzerland 2021 Equine Prohibited Substances List - BANNED SUBSTANCES . Prohibited Substances include any other substance with a similar chemical structure or similar biological effect(s). . Prohibited Substances that are identified as Specified Substances in the List below should not in any way be considered less important or less dangerous than other Prohibited Substances. Rather, they are simply substances which are more likely to have been ingested by Horses for a purpose other than the enhancement of sport performance, for example, through a contaminated food substance. Sedative Antidiabetic Antipsychotic Chlorthalidone Diuretic Chlorthenoxazine Non-steroidal anti-inflammatory drug Muscle relaxant Cicloprofen Non-steroidal anti-inflammatory drug Cilazapril Antihypertensive Vasodilator Beta agonist Local anaesthetic Cinchophen Non-steroidal anti-inflammatory drug Antidepressant Clibucaine Local anaesthetic Clidinium Anticholinergic Anxiolytic Stimulant Antidepressant Clocortolone Clofenamid Carbonate anhydrase inhibitor Sedative Clomiphene Oestrogen (Clomiprimine) Antidepressant Clomiprimine (Clomipramine) Antidepressant Anxiolytic Non-steroidal anti-inflammatory drug Beta blocker Anxiolytic Clormecaine Local anaesthetic Anabolic Clothiapine Antidepressant

1 December 2020 - Lausanne, Switzerland 2021 Equine Prohibited Substances List - BANNED SUBSTANCES . Prohibited Substances include any other substance with a similar chemical structure or similar biological effect(s). . Prohibited Substances that are identified as Specified Substances in the List below should not in any way be considered less important or less dangerous than other Prohibited Substances. Rather, they are simply substances which are more likely to have been ingested by Horses for a purpose other than the enhancement of sport performance, for example, through a contaminated food substance. Anxiolytic Anxiolytic Antipsychotic Cocaine Stimulant/local anaethestic (Specified Substance) Rheumatic treatment/anti- Conorphone Opioid analgesic Coroxon Anticoagulant Cortivazol Corticosteroid metabolite Coumarin Anticoagulant Cropropamide Stimulant Crotehamide Stimulant Antipsychotic Vasodilator Sedative Muscle relaxant Cycloguanil Antimalarial Local anaesthetic Psychoactive Antimuscarinic Diuretic Cycrimine Anticholinergic Anabolic Dapsone Antileprotic Muscle relaxant Dehydrochloromethyltestosterone Anabolic Dehydrochlorotestosterone Anabolic Anxiolytic (Specified Substance) Rheumatic treatment/anti-cancer Anxiolytic Deoxycorticosterone Corticosteroid Peptide agonist

1 December 2020 - Lausanne, Switzerland 2021 Equine Prohibited Substances List - BANNED SUBSTANCES . Prohibited Substances include any other substance with a similar chemical structure or similar biological effect(s). . Prohibited Substances that are identified as Specified Substances in the List below should not in any way be considered less important or less dangerous than other Prohibited Substances. Rather, they are simply substances which are more likely to have been ingested by Horses for a purpose other than the enhancement of sport performance, for example, through a contaminated food substance. Antipsychotic Antidepressant Desonide Corticosteroid Desoximethasone (Desoxymethasone) Corticosteroid Desoxyephedrine Stimulant Desoxymethasone (Desoximethasone) Corticosteroid Anabolic Desoxyvinyl-testosterone Anabolic Antitussive Narcotic Opioid analgesic Antitussive Opioid analgesic Antiarthritic Diamorphine () Narcotic Diaveridine Folic acid antagonist Muscle relaxant Psychoactive Dibucaine Local anaesthetic Dichlorisone Corticosteroid Dichlorphenamide Carbonic anhydrase inhibitor Dicumarol Anticoagulant Diethylpropion Anorexic Opioid analgesic Psychedelic Diflorasone acetate Corticosteroid Diflucortolone Corticosteroid Analgesic Anti-arrhythmic Opioid analgesic Dihydrocodeinone Opioid analgesic

1 December 2020 - Lausanne, Switzerland 2021 Equine Prohibited Substances List - BANNED SUBSTANCES . Prohibited Substances include any other substance with a similar chemical structure or similar biological effect(s). . Prohibited Substances that are identified as Specified Substances in the List below should not in any way be considered less important or less dangerous than other Prohibited Substances. Rather, they are simply substances which are more likely to have been ingested by Horses for a purpose other than the enhancement of sport performance, for example, through a contaminated food substance. Opioid analgesic Diisopropylamine Vasodilator Dimefline Respiratory stimulant Dimethindene Antipruritic Dimethisoquin Local anaesthetic Stimulant Dimethyltryptamine Psychedelic Diphenadione Anticoagulant Opioid agonist Opioid analgesic Opioid analgesic Bronchodilator Antiplatelet Anti-arrhythmic Disulfiram Aldehyde dehydrohenase inhibitor Antipsychotic Cholinesterase inhibitor Beta 2 agonist Dothiepin Antidepressant Doxacurium Muscle relaxant Antidepressant Antispasmodic Dromostanolone Anabolic Antipsychotic Diuretic Anabolic Antidepressant Dyclonine Oral anaesthetic Dyphylline Muscle relaxant Ecgonine methyl Cocaine metabolite Efaproxiral Haemoglobin modifier relief

1 December 2020 - Lausanne, Switzerland 2021 Equine Prohibited Substances List - BANNED SUBSTANCES . Prohibited Substances include any other substance with a similar chemical structure or similar biological effect(s). . Prohibited Substances that are identified as Specified Substances in the List below should not in any way be considered less important or less dangerous than other Prohibited Substances. Rather, they are simply substances which are more likely to have been ingested by Horses for a purpose other than the enhancement of sport performance, for example, through a contaminated food substance. Sedative Emepronium Antispasmodic Anxiolytic Endorphins Endogenous Endogenous pain relief Stimulant Analgesic Epi- Anabolic Epiternbolone Anabolic Anabolic Diuretic Ergonovine (Specified Substance) Vasoconstrictor (Specified Substance) Plant alkaloid Erythrityl tetranitrate Blood vessel relaxant (EPO), recombinant EPO Erythropoiesis and synthetic analogues Beta blocker Anxiolytic Estranediol Anabolic. Threshold substance in male Horse (other than geldings): 0.045 microgram free and glucuroconjugated 5α--3β, 17α-diol per millilitre in urine when, at the screening stage, the free and glucuroconjugated 5αestrane-3β, 17α-diol exceeds the free and glucuroconjugated 5,10 estrene-3β,17α-diol in the urine Adrenergic Bronchodilator Stimulant Etanercept Tumor necrosis factor inhibition Ethacrynic acid Diuretic Ethamivan Respiratory stimulant Ethamsylate Haemostatic Ethaverine Vasodilator Sedative Ethiazide Diuretic

1 December 2020 - Lausanne, Switzerland 2021 Equine Prohibited Substances List - BANNED SUBSTANCES . Prohibited Substances include any other substance with a similar chemical structure or similar biological effect(s). . Prohibited Substances that are identified as Specified Substances in the List below should not in any way be considered less important or less dangerous than other Prohibited Substances. Rather, they are simply substances which are more likely to have been ingested by Horses for a purpose other than the enhancement of sport performance, for example, through a contaminated food substance. Sedative Oestrogen Opioid analgesic Ethopropazine Antimuscarinic Anti-epileptic Carbonic anhydrase inhibitor Anxiolytic Ethylamphetamine Stimulant Anabolic Ethylisobutrazine Sedative Opioid analgesic Ethylnorepinephrine Bronchodilator Local anaesthetic Anxiolytic Stimulant Anabolic Anxiolytic Non-steroidal anti-inflammatory drug Stimulant Sedative Non-steroidal anti-inflammatory drug Opioid analgesic Aromatase inhibitor Stimulant Febaramate Muscle relaxant Anticonvulsant Antihypertensive Non-steroidal anti-inflammatory drug Stimulant Fencamfamine Stimulant Stimulant

1 December 2020 - Lausanne, Switzerland 2021 Equine Prohibited Substances List - BANNED SUBSTANCES . Prohibited Substances include any other substance with a similar chemical structure or similar biological effect(s). . Prohibited Substances that are identified as Specified Substances in the List below should not in any way be considered less important or less dangerous than other Prohibited Substances. Rather, they are simply substances which are more likely to have been ingested by Horses for a purpose other than the enhancement of sport performance, for example, through a contaminated food substance. Non-steroidal anti-inflammatory drug Non-steroidal anti-inflammatory drug (Fenetylline, Phenethylline, Stimulant Phenetylline) Fenetylline (Fenethylline, Phenethylline, Stimulant Phenetylline) Stimulant Vasodilator Non-steroidal anti-inflammatory drug Psychoactive Fenpiprane Gastrointestinal disorders Stimulant Non-steroidal anti-inflammatory drug Opioid analgesic Pain relief Non-steroidal anti-inflammatory drug Antispasmodic Anti-arrhythmic Non-steroidal anti-inflammatory drug Flouroprednisolone (Fluprednisolone) Corticosteroid Fluandrenolide (Fluandrenolone, Corticosteroid Fludroxycortide) Fluandrenolone (Fluandrenolide, Corticosteroid Fludroxycortide) Sedative Anxiolytic Fludrocortisone (Fluorocortisone) Corticosteroid Fludroxycortide (Fluandrenolide, Corticosteroid Fluandrenolone) Non-steroidal anti-inflammatory drug Flumethazide Diuretic Antihypertensive Corticosteroid Anxiolytic

1 December 2020 - Lausanne, Switzerland 2021 Equine Prohibited Substances List - BANNED SUBSTANCES . Prohibited Substances include any other substance with a similar chemical structure or similar biological effect(s). . Prohibited Substances that are identified as Specified Substances in the List below should not in any way be considered less important or less dangerous than other Prohibited Substances. Rather, they are simply substances which are more likely to have been ingested by Horses for a purpose other than the enhancement of sport performance, for example, through a contaminated food substance. Fluocinolone Corticosteroid Fluocinolone acetonide Corticosteroid Fluocinonide Corticosteroid Fluocortolone Corticosteroid Fluopromazine () Antipsychotic Fluoresone Anti-epileptic Fluorocortisone (Fludrocortisone) Corticosteroid Corticosteroid Fluorophenethylamine Stimulant Fluoroprednisolone Corticosteroid Antidepressant Anabolic Flupenthixol Antidepressant Antipsychotic Analgesic Fluprednisolone (Flouroprednisolone) Corticosteroid Anxiolytic Non-steroidal anti-inflammatory drug Antipsychotic Anxiolytic Antidepressant Anabolic Aromatase inhibitor Fosinopril Antihypertensive Anticonvulsant Anabolic Furazadrol Anabolic Stimulant Alzheimer - alkaloid Gallamine Muscle relaxant Gamma amino (GABA) Amino acid Gamma-Butyrolactone (GBL) Sedative

1 December 2020 - Lausanne, Switzerland 2021 Equine Prohibited Substances List - BANNED SUBSTANCES . Prohibited Substances include any other substance with a similar chemical structure or similar biological effect(s). . Prohibited Substances that are identified as Specified Substances in the List below should not in any way be considered less important or less dangerous than other Prohibited Substances. Rather, they are simply substances which are more likely to have been ingested by Horses for a purpose other than the enhancement of sport performance, for example, through a contaminated food substance. Gamma-Hydroxybutyrate (GHB) Sedative Anxiolytic Anabolic Sedative Growth Factors Growth promotion Growth Hormone (GH) - or analogues Growth promotion Sedative Antihypertensive Antihypertensive Sympatholytic GW1516 Anabolic Haemaglobin analogues Oxygen transport Halcinonide Corticosteroid Halobetasol Corticosteroid Halodrol Anabolic Neuroleptic Psychoactive Stimulant Heroin (Diamorphine) Narcotic Hexafluorenium Muscle relaxant Sedative Antimuscarinic Local anaesthetic Anticholenergic Homophenazine Psychiatric drug Hydralazine Vasodilator; afterload reducer Opioid analgesic Diuretic Opioid analgesic Opioid analgesic Hydroxyamphetamine Stimulant

1 December 2020 - Lausanne, Switzerland 2021 Equine Prohibited Substances List - BANNED SUBSTANCES . Prohibited Substances include any other substance with a similar chemical structure or similar biological effect(s). . Prohibited Substances that are identified as Specified Substances in the List below should not in any way be considered less important or less dangerous than other Prohibited Substances. Rather, they are simply substances which are more likely to have been ingested by Horses for a purpose other than the enhancement of sport performance, for example, through a contaminated food substance. Hydroxyephedrine () Stimulant Hydroxygamma amino butyric acid (hydroxy-GABA) Hydroxytestosterone Anabolic ( isomer) Anticholenergic Ibandronate Bisphosphonates Psychoactive indole Anti-arrhythmic Vasodilator Antidepressant Diuretic Non-steroidal anti-inflammatory drug Antihypertensive Infliximab Therapeutic antibody Antidepressant Antidepressant Anxiolytic Irbesartan Antihypertensive Antitussive Antidepressant Isoetharine Beta 2 adrenergic receptor agonist Analgesic Isometheptane Stimulant Sympathomimetic (Isoprotorenol) Bronchodilator Anticholinergic Isoprotorenol (Isoprenaline) Bronchodilator Isopyrin (Ramifenazone) Pain relief Isosorbide dinitrate Vasodilator Non-steroidal anti-inflammatory drug blocker Non-steroidal anti-inflammatory drug Anxiolytic

1 December 2020 - Lausanne, Switzerland 2021 Equine Prohibited Substances List - BANNED SUBSTANCES . Prohibited Substances include any other substance with a similar chemical structure or similar biological effect(s). . Prohibited Substances that are identified as Specified Substances in the List below should not in any way be considered less important or less dangerous than other Prohibited Substances. Rather, they are simply substances which are more likely to have been ingested by Horses for a purpose other than the enhancement of sport performance, for example, through a contaminated food substance. Krypton Hypoxia Inducible Factor (HIF) Activator Beta blocker Anticonvulsant Anxiolytic Leptazole (Pentylenetetrazole) Stimulant Letosteine Mucolytic Aromatase inhibitor Beta blocker Levodopa Di hydroxythenylalanine substitute Opioid analgesic Boosts brain uptake of Opioid analgesic LGD-4033 Anabolic Anti-arrhythmic Mood stabiliser Respiratory stimulant Opioid analgesic Antidepressant Anxiolytic Anxiolytic Anxiolytic Non-steroidal anti-inflammatory drug Losartan Antihypertensive Antipsychotic Lucanthone Radiation sensitizer Non-steroidal anti-inflammatory drug Beta agonist Madol Anabolic Antidepressant Anorexic MDA (Methylenedioxyamphetamine) Stimulant

1 December 2020 - Lausanne, Switzerland 2021 Equine Prohibited Substances List - BANNED SUBSTANCES . Prohibited Substances include any other substance with a similar chemical structure or similar biological effect(s). . Prohibited Substances that are identified as Specified Substances in the List below should not in any way be considered less important or less dangerous than other Prohibited Substances. Rather, they are simply substances which are more likely to have been ingested by Horses for a purpose other than the enhancement of sport performance, for example, through a contaminated food substance. MDEA Stimulant (Methylenedioxyethylamphetamine) MDMA Stimulant (Methylenedioxymethamphetamine) Mono- oxidase inhibitor Antispasmodic Sedative Nicotine antagonist Stimulant Meconine (Specified Substance) Opioid Anxiolytic Medrysone Corticosteroid Non-steroidal anti-inflammatory drug Stimulant Stimulant Diuretic Meldonium Antiischaemia Antipsychotic N-methyl D-asparate Meparfynol Anxiolytic Mepazine Antipsychotic Muscle relaxant Meperidine () Opioid analgesic Muscle relaxant Stimulant Anticonvulsant Mephobarbital Sedative Beta blocker Meprednisone Corticosteroid (Meprobromate) Anxiolytic Meprobromate (Meprobamate) Anxiolytic Local anaesthetic Opioid analgesic

1 December 2020 - Lausanne, Switzerland 2021 Equine Prohibited Substances List - BANNED SUBSTANCES . Prohibited Substances include any other substance with a similar chemical structure or similar biological effect(s). . Prohibited Substances that are identified as Specified Substances in the List below should not in any way be considered less important or less dangerous than other Prohibited Substances. Rather, they are simply substances which are more likely to have been ingested by Horses for a purpose other than the enhancement of sport performance, for example, through a contaminated food substance. Diuretic Merbaphen Diuretic Mercaptomerin Diuretic Diuretic Mesalamine () Non-steroidal anti-inflammatory drug Mesalazine (Mesalamine) Non-steroidal anti-inflammatory drug Stimulant Neuroleptic Anabolic Anabolic Anxiolytic Metaproterenol Bronchodilator Stimulant Muscle relaxant Opioid analgesic Hypotensive Oestrogen Stimulant Methandienone Anabolic Anabolic Methandrostenolone Anabolic Antimuscarinic Sedative Sedative Anabolic Methazolamide Diuretic Psychoactive Methenolone Anabolic Methimazole Antihyperthyroidsim Methixene Antispasmodic Sedative Immunomodulator

1 December 2020 - Lausanne, Switzerland 2021 Equine Prohibited Substances List - BANNED SUBSTANCES . Prohibited Substances include any other substance with a similar chemical structure or similar biological effect(s). . Prohibited Substances that are identified as Specified Substances in the List below should not in any way be considered less important or less dangerous than other Prohibited Substances. Rather, they are simply substances which are more likely to have been ingested by Horses for a purpose other than the enhancement of sport performance, for example, through a contaminated food substance. Methotrimeprazine Antipsychotic Non-steroidal anti-inflammatory drug Methscopolamine (Methyl ) Methsuximide Anticonvulsant Diuretic Methyl Scopolamine (Methscopolamine) Muscarinic antagonist Methylaminorex Stimulant Anticholinergic Methylchlorthiazide (Methylclothiazide) Diuretic Methylclothiazide (Methylchlorthiazide) Diuretic Anabolic Methyldihydromorphinone Opioid analgesic Antihypertensive Methylenedioxyamphetamine (MDA) Stimulant Methylenedioxyethylamphetamine Stimulant (MDEA) Methylenedioxymethamphetamine Stimulant (MDMA) Methylephedrine Stimulant Methylergonovine Vasoconstriction Methylhexaneamine Stimulant Methylmethcathinone Psychoactive Methylnortestosterone Anabolic Stimulant Methylprylon () Sedative Methylpseudoephedrine Stimulant Anabolic Methyltrienolone Anabolic Methyprylon (Methylprylon) Sedative 5-hydroxytryptamine receptor antagonist Diuretic Beta blocker

1 December 2020 - Lausanne, Switzerland 2021 Equine Prohibited Substances List - BANNED SUBSTANCES . Prohibited Substances include any other substance with a similar chemical structure or similar biological effect(s). . Prohibited Substances that are identified as Specified Substances in the List below should not in any way be considered less important or less dangerous than other Prohibited Substances. Rather, they are simply substances which are more likely to have been ingested by Horses for a purpose other than the enhancement of sport performance, for example, through a contaminated food substance. Muscle relaxant Diuretic Beta blocker Metrenperone Antipyretic synthesis inhibitor Anxiolytic Anti-arrhythmic Psychoactive Antihypertensive Anabolic Vasopressor Phosphodiesterase 3 inhibitor Vasodilator Mirtazepine Antidepressant Mivacurium Muscle relaxant Modafanil Stimulant Non-steroidal anti-inflammatory drug Molidustat Hypoxia Inducible Factor (HIF) Activator Antipsychotic Corticosteroid Leucotriene receptor antagonist - treatment

Moperone Antipsychotic Beta blocker Morphedrine Stimulant Opioid analgesic Antipsychotic Moxaverine Phosphodiesterase inhibition (Specified Substance) Parasympathomimetic Myoinositol tripyrophosphate Pyrophosphate Non-steroidal anti-inflammatory drug Beta blocker

1 December 2020 - Lausanne, Switzerland 2021 Equine Prohibited Substances List - BANNED SUBSTANCES . Prohibited Substances include any other substance with a similar chemical structure or similar biological effect(s). . Prohibited Substances that are identified as Specified Substances in the List below should not in any way be considered less important or less dangerous than other Prohibited Substances. Rather, they are simply substances which are more likely to have been ingested by Horses for a purpose other than the enhancement of sport performance, for example, through a contaminated food substance. Anti-arrhythmic Naepaine Local anaesthetic Vasodilator Opioid analgesic Opioid receptor agonist and antagonist Opioid receptor antagonist (Nortestosterone) Anabolic Sympathomimetic 5-hydroxytryptamine agonist (migraine treatment)

Nebivolol Beta blocker Mast cell stabiliser Psychoactive Non opioid analgesic Neridronate Bisphosphonates Antidepressant Antihypertensive Nicotine Stimulant Nicoumalone Anticoagulant Anti-angina Beta blocker Non-steroidal anti-inflammatory drug Stimulant Non-steroidal anti-inflammatory drug Anxiolytic Antihypertensive Anxiolytic Dopamine re-uptake inhibitor Topical analgesic/irritant Norandrostenediol Anabolic Norandrostenedione Anabolic Norbolethone Anabolic Anabolic

1 December 2020 - Lausanne, Switzerland 2021 Equine Prohibited Substances List - BANNED SUBSTANCES . Prohibited Substances include any other substance with a similar chemical structure or similar biological effect(s). . Prohibited Substances that are identified as Specified Substances in the List below should not in any way be considered less important or less dangerous than other Prohibited Substances. Rather, they are simply substances which are more likely to have been ingested by Horses for a purpose other than the enhancement of sport performance, for example, through a contaminated food substance. Cocaine metabolite Nordiazepam Tranquiliser Anabolic Stimulant Stimulant Norfluoxetine Fluoxetine metabolite Normethandrolone Anabolic Norpseudoephedrine (Cathine) Stimulant Nortestosterone (Nandrolone) Anabolic Antidepressant Antitussive Nylidrin (Buphenine) Sympathomimetic Octadecafluoronaphthalene Artificial carriers in blood (Perfluorodecalin) Stimulant Antipsychotic Olmesartan Antihypertensive Olpadronate Bisphosphonates Olsalazine Gut anti-inflammatory Psychoactive Opromazine Bronchodilator (Specified Substance) Opioid analgesic Osterine Selective Modulator Anabolic Oxaflumazine Psychosedative Anabolic Non-steroidal anti-inflammatory drug Anxiolytic Anticonvulsant Oxethazaine Topical anaesthetic Oxilofrine (Hydroxyephedrine) Stimulant Oxolamine Antitussive

1 December 2020 - Lausanne, Switzerland 2021 Equine Prohibited Substances List - BANNED SUBSTANCES . Prohibited Substances include any other substance with a similar chemical structure or similar biological effect(s). . Prohibited Substances that are identified as Specified Substances in the List below should not in any way be considered less important or less dangerous than other Prohibited Substances. Rather, they are simply substances which are more likely to have been ingested by Horses for a purpose other than the enhancement of sport performance, for example, through a contaminated food substance. Beta blocker Oxybuprocaine Local anaesthetic Opioid analgesic Oxyguno Anabolic Anabolic Topical Anabolic Opioid analgesic Neuroleptic Antimuscarinic Oxyphenonium Antimuscarinic Antipsychotic Pamidronate Bisphosphonates Palmitoylethanolamid Analgesic Pancuronium Muscle relaxant Papaverine (Specified Substance) - muscle spasm treatment Anticonvulsant Anabolic Paramethasone Corticosteroid Mono-amine oxidase inhibitor Antidepressant Stimulant Beta blocker Antipsychotic Pentaerythritol Tetranitrate Vasodilator Narcotic Pentetrazol Stimulant Vasodilator Sedative Pentoxyverine (Carbetapentane) Antitussive Pentylenetetrazole (Leptazole) Stimulant

1 December 2020 - Lausanne, Switzerland 2021 Equine Prohibited Substances List - BANNED SUBSTANCES . Prohibited Substances include any other substance with a similar chemical structure or similar biological effect(s). . Prohibited Substances that are identified as Specified Substances in the List below should not in any way be considered less important or less dangerous than other Prohibited Substances. Rather, they are simply substances which are more likely to have been ingested by Horses for a purpose other than the enhancement of sport performance, for example, through a contaminated food substance. Perfluorocarbons Artificial gas carriers in blood Perfluorodecalin Artificial gas carriers in blood (Octadecafluoronaphthalene) Perfluorooctylbromide Artificial gas carriers in blood Perfluorotripropylamine Artificial gas carriers in blood (Pericyazine) Antipsychotic Pericyazine (Periciazine) Antipsychotic Perinodopril Antihypertensive Hypnotic Tranquiliser/ derivative Pethidine (Meperidine) Opioid analgesic Anticonvulsant Phenacetin (Acetophenetidin) Analgesic Tranquiliser Opioid analgesic Analgesic Analgesic Anaesthetic Stimulant Psychoactive Phenethylline (Fenethylline, Fenetylline, Stimulant Phenetylline) Phenetylline(Fenethylline, Fenetylline, Stimulant Phenethylline) Central Nervous System Phenindione Anticoagulant Stimulant Sedative Antihypertensive Phenprocoumon Anticoagulant Stimulant Muscle relaxant Anticonvulsant

1 December 2020 - Lausanne, Switzerland 2021 Equine Prohibited Substances List - BANNED SUBSTANCES . Prohibited Substances include any other substance with a similar chemical structure or similar biological effect(s). . Prohibited Substances that are identified as Specified Substances in the List below should not in any way be considered less important or less dangerous than other Prohibited Substances. Rather, they are simply substances which are more likely to have been ingested by Horses for a purpose other than the enhancement of sport performance, for example, through a contaminated food substance. Vasodilator Phenyliprazine Antidepressant Phenylpiracetam (Carphedon) Stimulant Stimulant Antitussive Stimulant Stimulant Opioid analgesic Antipsychotic Anxiolytic Beta blocker Pipamazine Anti-emetic/mild tranquiliser Antipsychotic Pipecuronium Muscle relaxant Pipenzolate Antimuscarinic Anxiolytic Piper Methysticum () Anti-psychotic Sedative Anticholinergic Anticholinergic Local anaesthetic Adrenergic blocker Antipsychotic Pipradol () Stimulant Pipradrol (Pipradol) Stimulant Antipsychotic Stimulant Diuretic Non-steroidal anti-inflammatory drug Antimigraine Diuretic Beta blocker

1 December 2020 - Lausanne, Switzerland 2021 Equine Prohibited Substances List - BANNED SUBSTANCES . Prohibited Substances include any other substance with a similar chemical structure or similar biological effect(s). . Prohibited Substances that are identified as Specified Substances in the List below should not in any way be considered less important or less dangerous than other Prohibited Substances. Rather, they are simply substances which are more likely to have been ingested by Horses for a purpose other than the enhancement of sport performance, for example, through a contaminated food substance. Anabolic Anxiolytic Vasodilator Muscle relaxant Anticonvulsant Diuretic Procarbazine Chemotherapy Beta adrenergic receptor agonist Antipsychotic Anticholinergic Cholecystokinin antagonist Proguanil Antimalarial Stimulant Anti-arrhythmic Anti-arrhythmic Sedative Anaesthetic Proparacaine () Local anaesthetic Tranquiliser Propionylpromazine Tranquiliser Opioid receptor agonist Local anaesthetic Propoxyphene Opioid analgesic Stimulant Non-steroidal anti-inflammatory drug Non-steroidal anti-inflammatory drug Anabolic Antipsychotic Sympathomimetic Stimulant antidepressant Sedative Proxymetacaine (Proparacaine) Local anaesthetic

1 December 2020 - Lausanne, Switzerland 2021 Equine Prohibited Substances List - BANNED SUBSTANCES . Prohibited Substances include any other substance with a similar chemical structure or similar biological effect(s). . Prohibited Substances that are identified as Specified Substances in the List below should not in any way be considered less important or less dangerous than other Prohibited Substances. Rather, they are simply substances which are more likely to have been ingested by Horses for a purpose other than the enhancement of sport performance, for example, through a contaminated food substance. Bronchodilator Stimulant Psychedelic Pyridostigmine Anticholinesterase Sedative Anti-psychotic Quinalbarbital (Secobarbitone) Sedative Anabolic Quinisocaine Topical anaesthetic Beta agonist RAD140 Anabolic Oestrogen receptor modulator Ramifenazone (Isopyrin) Pain relief Rauwolfia Tranquiliser Opioid analgesic Bronchodilator Tranquiliser Bronchodilator Risedronate Bisphosphonates Antipsychotic Tocolytic Non-steroidal anti-inflammatory drug Local anaesthetic Roxadustat Hypoxia Inducible Factor (HIF) Activator Non-steroidal anti-inflammatory drug SARM LGD-4033 Anabolic SARM YK-11 Anabolic SARM S-4 Anabolic Secobarbitone (Quinalbarbital) Sedative Stimulant Antidepressant Stimulant

1 December 2020 - Lausanne, Switzerland 2021 Equine Prohibited Substances List - BANNED SUBSTANCES . Prohibited Substances include any other substance with a similar chemical structure or similar biological effect(s). . Prohibited Substances that are identified as Specified Substances in the List below should not in any way be considered less important or less dangerous than other Prohibited Substances. Rather, they are simply substances which are more likely to have been ingested by Horses for a purpose other than the enhancement of sport performance, for example, through a contaminated food substance. Vasodilator (Specified Substance) Anti-arrhythmic Diuretic Anabolic Anabolic Muscular convulsions Anticonvulsant Opioid analgesic Antipsychotic Non-steroidal anti-inflammatory drug Antipsychotic Serotonin agonist - migraine treatment (Specified Substance) Stimulant Oestrogen receptor modulator Tranquiliser Pain relief Non-steroidal anti-inflammatory drug Terazocin () Alpha adrenergic blocker Terazosin (Terazocin) Alpha adrenergic blocker Aromatase inhibitor Testosterone Anabolic. Threshold substance: 0.02 micrograms free and conjugated testosterone per millilitre in urine from geldings, or 0.055 micrograms free and conjugated testosterone per millilitre in urine from fillies and mares (unless in foal). Testosterone in plasma: 1x10-4 µg free testosterone per millilitre in plasma from geldings, fillies and mares (unless in foal) (THG) Anabolic

Thebaine (Specified Substance) Opioid alkaloid THG (Tetrahydrogestrinone) Anabolic

1 December 2020 - Lausanne, Switzerland 2021 Equine Prohibited Substances List - BANNED SUBSTANCES . Prohibited Substances include any other substance with a similar chemical structure or similar biological effect(s). . Prohibited Substances that are identified as Specified Substances in the List below should not in any way be considered less important or less dangerous than other Prohibited Substances. Rather, they are simply substances which are more likely to have been ingested by Horses for a purpose other than the enhancement of sport performance, for example, through a contaminated food substance. Anti-emetic Antipsychotic Cataleptic Antipsychotic Thiothixene Antipsychotic Psychoactive Thymosin (snythetic fragments) Anabolic Non-steroidal anti-inflammatory drug Anabolic Local anaesthetic Antidepressant Non-steroidal anti-inflammatory drug Non-steroidal anti-inflammatory drug Vaptans Tolycaine Local anaesthetic Diuretic Oestrogen receptor modulator Analgesic Sympathomimetic Mono-amine oxidase inhibitor Antidepressant Trena Anabolic Anabolic Anabolic Diuretic Anxiolytic Triflumeprazine Phenothiazene Antipsychotic Trifluoromethylphenyl piperazine Psychoactive Antipsychotic Triflupromazine (Fluopromazine) Antipsychotic Trihexylphenidyl () inhibitor

1 December 2020 - Lausanne, Switzerland 2021 Equine Prohibited Substances List - BANNED SUBSTANCES . Prohibited Substances include any other substance with a similar chemical structure or similar biological effect(s). . Prohibited Substances that are identified as Specified Substances in the List below should not in any way be considered less important or less dangerous than other Prohibited Substances. Rather, they are simply substances which are more likely to have been ingested by Horses for a purpose other than the enhancement of sport performance, for example, through a contaminated food substance. Trihexyphenidyl (Trihexylphenidyl) Acetylcholine inhibitor Local anaesthetic Trimeprazine Antipruritic Angina treatment Antidepressant Tripamide Antihypertensive Stimulant Bronchodilator Anxiolytic Pain relief Sedative Anticonvulsant Vasodilator Antidepressant Venom – naturally derived and synthetic Anti-arrhythmic Antidepressant Warfarin Anticoagulant Diuretic Hypoxia Inducible Factor (HIF) Activator Adrenergic Oestrogen agonist Zicotinide Analgesic Beta agonist/repartitioning agent Zimeldine Antidepressant Zoledronate Bisphosphonates Hypnotic Non-steroidal anti-inflammatory drug Hypnotic Antipsychotic

1 December 2020 - Lausanne, Switzerland 2021 Equine Prohibited Substances List - BANNED SUBSTANCES . Prohibited Substances include any other substance with a similar chemical structure or similar biological effect(s). . Prohibited Substances that are identified as Specified Substances in the List below should not in any way be considered less important or less dangerous than other Prohibited Substances. Rather, they are simply substances which are more likely to have been ingested by Horses for a purpose other than the enhancement of sport performance, for example, through a contaminated food substance.

BANNED METHODS

1. Manipulation of Blood and Blood Components (i.e. Blood Doping, ozone haemotherapy)

• Withdrawal, manipulation and re-infusion of homologous, heterologous, or autologous, blood products or blood cells into the circulatory system with the exception of those performed for lifesaving purposes or the use of veterinary regenerative therapies for the treatment of musculoskeletal injury or disease.

2. Gene Doping

• Any form of genetic modification

1 December 2020 - Lausanne, Switzerland