DOCSLIB.ORG

Abstractband

Total Page：16

File Type：pdf, Size：1020Kb

Download full-text PDF Read full-text
Abstractband 1 2 Table of Contents Table of Contents Table of Contents .......................................................................... 1 Welcome Address of the German Research Platform for Zoonoses .... 4 Welcome Note of the Federal Ministries ........................................... 6 Welcome Note of Public Health Representatives .............................. 8 Program ...................................................................................... 11 General Information ..................................................................... 24 Floor Plan .................................................................................... 28 Site Plan...................................................................................... 29 About the German Research Platform for Zoonoses ....................... 30 Oral Presentations ....................................................................... 32 Plenary Sessions .......................................................................... 33 Session 1: Epidemiology and modelling ......................................... 37 Session 2: Pathogen-cell interaction .............................................. 44 Session 3: Risikobewertung .......................................................... 51 Session 4: Antimicrobial use and resistance ................................... 55 Session 5: Public Health relevant zoonoses .................................... 62 Session 6: New and emerging zoonoses ........................................ 69 Session 7: Innate and adaptive immune response ......................... 78 Session 8: Novel methods, diagnostics, NGS and bioinformatics ..... 85 Session 9: One Health und neue Zoonosen ................................... 92 Poster Presentations .................................................................... 97 Poster Session Epidemiology and modelling ................................... 98 Poster Session Pathogen-cell interaction...................................... 109 Poster Session Antimicrobial use and resistance ........................... 119 Poster Session Novel methods, diagnostics and NGS .................... 127 Poster Session New and emerging zoonoses ................................ 138 Poster Session Free topics .......................................................... 158 List of Participants ..................................................................... 172 Personal notes ........................................................................... 198 3 Welcome Address of the German Research Platform for Zoonoses Welcome Address of the German Research Platform for Zoonoses Dear colleagues, We are delighted to welcome you to the National Symposium on Zoonoses Research 2015. The focus of this year’s conference is “Research meets Public Health.” Over the past year, the German Research Platform for Zoonoses has worked hard to close the gap between research and practical application, forging links between representatives from both sides. Against this background, we are very pleased that Ute Teichert (Akademie für öffentlichen Gesundheitsdienst Düsseldorf) and Jürgen Rissland (Fachausschuss Infektionsschutz im Bundesverband der Ärztinnen und Ärzte des öffentlichen Gesundheitsdienstes e.V. - BVÖGD) contributed to the planning of the symposium’s agenda and will moderate several sessions. Both Dr. Teichert and Dr. Rissland play an active role in public health services in Germany. This year’s program structure is intended to attract the attention of researchers and public health professionals alike (in human and in veterinary medicine). It will intensify exchange between these two stakeholder groups and encourage discourse among participants. To ensure the event is accessible to everyone, some segments will be held in English and others in German. Zoonoses and related research are key topics within public health services (including veterinary health services). And this year’s conference again offers an exciting and appealing program of keynotes and accompanying sessions. A particular highlight is the Public Health-Session on Thursday afternoon (to be held in German) that will address antibiotic resistance. Our Young Scientists Breakfast will take place on Friday morning. Early-stage researchers are invited to take advantage of this relaxed setting to talk with experienced colleagues about possible career paths and other topics. 4 Welcome Address of the German Research Platform for Zoonoses The conference is designed as a platform for exchanging up-to-date knowledge, meeting new partners and developing existing partnerships that span scientific disciplines and geographical boundaries. Let’s join forces and bring the One Health idea to life! We would like to take this opportunity to thank all those who have submitted abstracts, and prepared posters and presentations, some of whom have travelled a great distance to join us. All of you are making a positive contribution to the success of this conference. We hope you enjoy and benefit from the National Symposium on Zoonoses Research 2015. Stephan Ludwig Martin H. Groschup (Münster, Germany) (Isle of Riems, Germany) Sebastian C. Semler (Berlin, Germany) Directors of the German Research Platform for Zoonoses 5 Welcome Note of the Federal Ministries Welcome Note of the Federal Ministries For years, the scientific promotion of zoonoses control has been a priority of the federal government. For some time, we have been aware that a one-sided approach to human and animal health, food safety or the environment does not produce the comprehensive success in zoonoses control we are aiming for and which the citizens expect. Consequently, the motto of this year’s symposium is „Research meets Public Health“. According to the World Organization for Animal Health in Paris, about 60 to 70 % of all (new) diseases occurring in humans are caused by pathogens first recognized in animals. This alarming development has many reasons: • The close association of livestock and their keepers. • The increasing constriction of the natural habitat of wild animals causes an increasingly close contact between humans and animals - even in urban areas. • The arrival and spread of suitable live vectors for highly pathogenic and novel zoonotic pathogens, particularly exacerbated by climate change. • The vehement increase of international trade and tourism. • Change of climatic factors in the context of climate change. All together, enough reasons why zoonotic pathogens may colonize and multiply in animal and human populations and spread across continents within a day. As a result, the health of humans and animals is threatened. It also has a significant negative impact on society. In a highly developed country like ours, we must conquer these challenges. This is the responsibility of Public Health bodies, Public Veterinary authorities and Public Health services. Thus, it is imperative to put scientific results to practical use. To this end, the scientific clearing of unanswered questions, the development of efficient diagnostic and therapeutic methods, preventive measures and, finally, informing the public as well as surveillance of zoonotic pathogens are important steps. For an effective control and efficient political measures, it takes a comprehensive and interdisciplinary approach: 6 Welcome Note of the Federal Ministries “One health” – health cannot be divided - the responsibility for maintaining the health of humans and animals, however, is administratively divided and often also in science. This must be overcome. In order to achieve our goal according to the “One health” principle, health and veterinary authorities, agriculture, food industry, well informed consumers and science must work together. The scientists of national zoonoses research lay the foundation for this. Now, their scientific results must be put to practical use. Therefore, we wish all participants interesting discussions, new insights, creative ideas for future research initiatives and a successful conference! Dr. Joachim Klein Dr. Antina Ziegelmann Federal Ministry of Education Federal Ministry of Health and Research Dr. Ralf Rotheneder Federal Ministry of Food and Agriculture 7 Welcome Note of Public Health Representatives Welcome Note of Public Health Representatives Sehr geehrte Damen und Herren, liebe Kolleginnen und Kollegen, zum diesjährigen Nationalen Symposium für Zoonosenforschung heiße ich Sie als Vorsitzende des Bundesverbandes der Ärztinnen und Ärzte des Öffentlichen Gesundheitsdienstes gemeinsam mit meinem Kollegen, Herrn Dr. Jürgen Rissland, der Sprecher für den Fachausschuss Infektionsschutz im BVÖGD ist, herzlich willkommen. Wir erleben heute und auch morgen eine Besonderheit. „Research meets Public Health“. So lautet in diesem Jahr der Untertitel für diese Veranstaltung. Und man könnte einen Ihnen vielleicht noch vertrauten, ehemaligen Spitzenpolitiker zitieren, der 1989 gesagt hat: „es wächst zusammen, was zusammengehört!“. Das Zitat stammt von Willy Brand und bezog sich ursprünglich auf die beiden deutschen Staaten nach der Wiedervereinigung vor nun rund 26 Jahren. „Es wächst zusammen, was zusammengehört“ – diese Aussage gilt aber auch für das Thema Zoonosen und öffentliche Gesundheit. Fast 70 % der heute für den Menschen bedeutsamen Infektionskrankheiten sind ursprünglich zunächst beim Tier aufgetreten und dann auf den Menschen übergegangen. Darunter so bedeutsame wie das humane Immunschwächevirus oder auch lebensmittelbedingte Infektionen, aber in jüngerer Vergangenheit vor allem Coronaviren als
Load more

Recommended publications
  • A Data-Driven Agent-Based Approach
    medRxiv preprint doi: https://doi.org/10.1101/2020.09.04.20188680; this version posted January 6, 2021. The copyright holder for this preprint (which was not certified by peer review) is the author/funder, who has granted medRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY-NC-ND 4.0 International license . SAFE REOPENING STRATEGIES FOR EDUCATIONAL INSTITUTIONS DURING COVID-19: A DATA-DRIVEN AGENT-BASED APPROACH UJJAL K MUKHERJEE, SUBHONMESH BOSE, ANTON IVANOV, SEBASTIAN SOUYRIS, SRIDHAR SESHADRI, PADMAVATI SESHADRI, RONALD WATKINS, AND YUQIAN XU Abstract. Many educational institutions have partially or fully closed all operations to cope with the challenges of the ongoing COVID-19 pandemic. In this paper, we explore strategies that such institutions can adopt to conduct safe reopening and resume operations during the pandemic. The research is motivated by the University of Illinois at Urbana-Champaign's (UIUC's) SHIELD program, (https://www.uillinois.edu/shield), which is a set of policies and strategies, including rapid saliva-based COVID-19 screening, for ensuring safety of students, faculty and staff to conduct in-person operations, at least partially. Specifically, we study how rapid bulk testing, contact tracing and preventative measures such as mask wearing, sanitization, and enforcement of social distancing can allow institutions to manage the epidemic spread. Research Design. This work combines the power of analytical epidemic modeling, data analysis and agent-based simulations to derive policy insights. We develop an analytical model that takes into account the asymptomatic transmission of COVID-19, the effect of isolation via testing (both in bulk and through contact tracing) and the rate of contacts among people within and outside the institution.
    [Show full text]
  • International Security Forum Bonn 2020 Report
    INTERNATIONAL SECURITY FORUM BONN 2020 A TIME OUT OF JOINT – NEW REALITIES, NEW IDEAS 1-5 DECEMBER 2020 FULL REPORT RAPPORTEURS: CORNELIUS LILIE LUKAS PAUL SCHMELTER International Security Forum Bonn 2020 3 FOREWORD The International Security Forum Bonn 2020 facilitated Like no other event in the 21st century, the SARS- a high-level international dialogue on contemporary CoV-2-pandemic has put the international order, as topics of foreign and security policy. The goal of the well as the societies, economies, and policies of Forum was to foster exchange between experts and almost every country on earth to the test. It remains practitioners, to identify vital aspects of a successful to be seen whether those in positions of influence will European foreign and security policy, and to develop succeed in containing the pandemic and in respond- holistic strategic solutions for pressing problems. The ing successfully to its consequences. 2020 Forum focused on the challenges posed by the shifts in transatlantic relations, discussed the findings As hardly ever before, political, and economic decision- of the Task Force "The Future of Transatlantic Rela- makers depend on science – first on virologists, but tions", and evaluated the upcoming global geo-eco- also on other natural and social science expertise. nomic and geo-political rivalries which were reinforced Expertise and novel insights are key, particularly since by the SARS-CoV-2-pandemic. It was concluded by a any political or inaction is likely to have serious social, two-day workshop on strategic foresight. economic, and political consequences. From left to right: Prof. Dr. Wolfram Hilz, Prof.
    [Show full text]
  • Sequencing of SARS-Cov-2
    TECHNICAL NOTE Sequencing of SARS-CoV-2 23 December 2020 Introduction In January 2020, a previously unknown coronavirus strain was identified as the cause of a respiratory infection and death in humans [1]. The first viral genome was sequenced using high throughput sequencing (HTS) from a sample collected in Wuhan, China. This virus, belonging to the viral species Severe acute respiratory syndrome– related coronavirus, has been subsequently named SARS-CoV-2 and the associated disease coronavirus disease 2019 (COVID-19) [2]. Sequencing of (partial) genes and whole genomes (WGS) have been proven as powerful methods to investigate viral pathogen genomes, understand outbreak transmission dynamics and spill-over events and screen for mutations that potentially have an impact on transmissibility, pathogenicity, and/or countermeasures (e.g. diagnostics, antiviral drugs and vaccines). The results are key to informing outbreak control decisions in public health. Scope A standardised pipeline to characterise, name and report SARS-CoV-2 sequences has not been established yet, but many countries of the WHO European Region have been sequencing SARS-CoV-2 variants since the beginning of the pandemic and reporting the sequences to the Global Initiative on Sharing All Influenza Data (GISAID) or other publicly accessible databases [3]. Combining information of virus characteristics with clinical and epidemiological data is important. Genetic characterisation of SARS-CoV-2 is used to monitor viral evolution and to timely identify potential markers of increased transmissibility, severity of disease or altered antigenicity. Emerging hypotheses will need to be further investigated in ex vivo, in vitro or animal models. Sequence data will become increasingly important as SARS-CoV-2 vaccines and antivirals become available, in order to monitor the match of the circulating variants with the vaccine and the possible emergence of antiviral resistance.
    [Show full text]
  • THE CORONAVIRUS CZAR the COVID-19 Pandemic Has Made German Virologist Christian Drosten an Unlikely Cult Figure
    NEWS FEATURES Downloaded from http://science.sciencemag.org/ on May 13, 2020 THE CORONAVIRUS CZAR The COVID-19 pandemic has made German virologist Christian Drosten an unlikely cult figure By Kai Kupferschmidt, in Berlin PHOTO: VOLKER LANNERT VOLKER PHOTO: 462 1 MAY 2020 • VOL 368 ISSUE 6490 sciencemag.org SCIENCE Published by AAAS NEWS but now one of those pathogens was killing virus he has spent most of his life studying. patients in a hospital a few blocks away. “If this were influenza, for instance, I would And instead of teaching virology to a few not be doing this,” he says. hundred students, Drosten now addresses hundreds of thousands of anxious Germans. DROSTEN’S CORONAVIRUS CAREER effectively Twice a week around 10 a.m., he sets a blue began on Saturday, 15 March 2003, when a microphone on his desk, puts on head- 32-year-old doctor from Singapore named phones, and waits for a science journalist Leong Hoe Nam was taken off a plane in from German radio station NDR Info to call Frankfurt, Germany, and taken to the city’s him. For the next 40 minutes, he answers university clinic. Leong had treated patients questions about vaccines, respiratory drop- in Singapore before attending an infectious lets, school closures, or masks. The podcast, diseases course in New York City, and had de- simply titled Coronavirus Update, has made veloped symptoms consistent with an alarm- Drosten the face, or rather the voice, of the ing new respiratory disease that was rapidly pandemic in Germany. More than 1 million people regularly download what has become the country’s most popular podcast.
    [Show full text]
  • The COVID-19 Pandemic Has Made German Virologist Christian Drosten an Unlikely Cult Figure
    NEWS FEATURES Downloaded from http://science.sciencemag.org/ on May 1, 2020 THE CORONAVIRUS CZAR The COVID-19 pandemic has made German virologist Christian Drosten an unlikely cult figure By Kai Kupferschmidt, in Berlin PHOTO: VOLKER LANNERT VOLKER PHOTO: 462 1 MAY 2020 • VOL 368 ISSUE 6490 sciencemag.org SCIENCE Published by AAAS NEWS but now one of those pathogens was killing virus he has spent most of his life studying. patients in a hospital a few blocks away. “If this were influenza, for instance, I would And instead of teaching virology to a few not be doing this,” he says. hundred students, Drosten now addresses hundreds of thousands of anxious Germans. DROSTEN’S CORONAVIRUS CAREER effectively Twice a week around 10 a.m., he sets a blue began on Saturday, 15 March 2003, when a microphone on his desk, puts on head- 32-year-old doctor from Singapore named phones, and waits for a science journalist Leong Hoe Nam was taken off a plane in from German radio station NDR Info to call Frankfurt, Germany, and taken to the city’s him. For the next 40 minutes, he answers university clinic. Leong had treated patients questions about vaccines, respiratory drop- in Singapore before attending an infectious lets, school closures, or masks. The podcast, diseases course in New York City, and had de- simply titled Coronavirus Update, has made veloped symptoms consistent with an alarm- Drosten the face, or rather the voice, of the ing new respiratory disease that was rapidly pandemic in Germany. More than 1 million people regularly download what has become the country’s most popular podcast.
    [Show full text]
  • Science Denial” and a “Policy of Contagion”: Germany’S Leading Virologists Condemn Government’S Anti-Lockdown Policy
    افغانستان آزاد – آزاد افغانستان AA-AA چو کشور نباشـد تن من مبـــــــاد بدين بوم و بر زنده يک تن مــــباد ھمه سر به سر تن به کشتن دھيم از آن به که کشور به دشمن دھيم www.afgazad.com [email protected] زبانھای اروپائی European Languages Gregor Link 11.04.2021 “Science denial” and a “policy of contagion”: Germany’s leading virologists condemn government’s anti-lockdown policy Although the number of COVID-19 patients in German intensive care units has been rising exponentially for four weeks, the federal and state governments refuse to close schools and businesses to contain the pandemic. In recent weeks, medical and scientific experts have been insisting on the implementation of a “hard lockdown,” as the more infectious and deadly B.1.1.7 virus strain is spreading unhindered and is now responsible for over 90 percent of all new infections, according to the Robert Koch Institute (RKI). Virologist Christian Drosten [email protected] ١ www.afgazad.com “I think all virologists agree that we need a hard lockdown immediately in this critical phase of the third wave,” Oliver Keppler, a professor of virology at Ludwig Maximilian University in Munich, told the Tagesschau TV news on Tuesday. “Honestly, I ask myself: where is it? It should have been implemented by now. There is no alternative. And we need it now, and preferably uniformly throughout Germany.” The German government, however, is doing absolutely nothing to comply with this demand. Instead, the government plans to expand its vaccination programme as infection incidence figures rise, in what amounts to a recipe for the emergence of vaccine-resistant virus mutants, according to experts such as Max Planck researcher Viola Priesemann.
    [Show full text]