CKMT2 Antibody Cat. No.: 62-636

CKMT2 Antibody

Specifications

HOST SPECIES: Rabbit

SPECIES REACTIVITY: Human

This CKMT2 antibody is generated from rabbits immunized with a KLH conjugated IMMUNOGEN: synthetic peptide between 391-419 amino acids from the C-terminal region of human CKMT2.

TESTED APPLICATIONS: WB

APPLICATIONS: For WB starting dilution is: 1:1000

PREDICTED MOLECULAR 48 kDa WEIGHT:

Properties

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by PURIFICATION: dialysis

CLONALITY: Polyclonal

ISOTYPE: Rabbit Ig

CONJUGATE: Unconjugated

September 27, 2021 1 https://www.prosci-inc.com/ckmt2-antibody-62-636.html PHYSICAL STATE: Liquid

BUFFER: Supplied in PBS with 0.09% (W/V) sodium azide.

CONCENTRATION: batch dependent

Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies STORAGE CONDITIONS: care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Additional Info

OFFICIAL SYMBOL: CKMT2

Creatine kinase S-type, mitochondrial, Basic-type mitochondrial kinase, Mib-CK, ALTERNATE NAMES: Sarcomeric mitochondrial , S-MtCK, CKMT2

ACCESSION NO.: P17540

PROTEIN GI NO.: 116242603

GENE ID: 1160

USER NOTE: Optimal dilutions for each application to be determined by the researcher.

Background and References

Mitochondrial creatine kinase (MtCK) is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate . Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic BACKGROUND: creatine kinase isoenzymes. Sarcomeric mitochondrial creatine kinase has 80% with the coding exons of ubiquitous mitochondrial creatine kinase. This contains sequences homologous to several motifs that are shared among some nuclear genes encoding mitochondrial proteins and thus may be essential for the coordinated activation of these genes during mitochondrial biogenesis.

ANTIBODIES FOR RESEARCH USE ONLY.

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September 27, 2021 2 https://www.prosci-inc.com/ckmt2-antibody-62-636.html