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Pharmacodynamics • Compared therapy are reported to be ex- with ferrous sulfate, Ferronord tremely rare with Ferronord-DLA. provides a more readily absorbed, Iron toxicity is likely to be encoun- fully utilized, and safely tolerated tered only with massive over- form of iron. The complex bond dosage. with amino acid protects the fer- rous iron from oxidation into in- Indications • Ferronord-DLA is OM bAY- LONG soluble and irritating compounds. indicated for the treatment of all :erronord:ol The amino acid component in- the common iron deficiency ane- C:11 leS creases absorption through the in- mias, including the hypochromic
rrof frootmont of iroft testinal mucosa, so that absorption anemia of pregnancy. 4.1kienty orowniat, of Ferronord is 5 times that of fer- rEit.TINSI El I AHIIIIATIY110.° / DO. rous sulfate. In the prolonged- Contraindications • There are no action form. the clinical advantages specific contraindications to the of Ferronord are enhanced because use of Ferronord-DLA in the pre- more iron is allowed to reach the scribed manner. small intestine, the site of optimal FERRONORD®-DLA CAPSULES absorption. During therapy with Dosage schedule • For adults the Ferronord-DLA, serum iron is ele- usual dose is one capsule each Chemistry • Ferronord is a brand vated within 3 hours, reticulocyte morning; in severe anemia a cap- of ferroglycine sulfate complex, an response is at a peak within 5 days, sule may be taken twice a day. equimolecular, chelated complex and hemoglobin levels are sharply Children receive the same dosage of ferrous sulfate and the amino increased within 3 weeks. Clinical in most cases. The capsules can be acid, glycine. The chelate bonding studies indicate that Ferronord- taken between meals. is such as to permit the ferrous DLA can be administered safely to iron to be released readily. In pregnant patients, those with gas- How • supplied • Ferronord-DLA Ferronord-DLA the pure hydrated trointestinal disorders, and in many capsules are available in bottles complex has been incorporated into cases those who have been intoler- of 30. prolonged-action granules formu- ant of other iron therapy. lated to provide 8 hours of thera- Manufacturer • Cooper, Tinsley peutic effect in cases of iron de- Toxicology • The side effects Laboratories, Inc., 229 Cleveland ficiency anemia. commonly encountered in iron Avenue, Harrison, New Jersey.