CDISC Controlled Terminology SDTM - 2012-03-23

CDISC NCI Submission Codelist Code Value Codelist Name CDISC Definition Extensible

C66767 ACN Action Taken with Study Action Taken with Study Treatment No Treatment

C66769 AESEV Severity/Intensity Scale A scale that defines the degree or state of disease existing in a patient as a result of the No for Adverse Events occurrence of an adverse event. (NCI)

C66780 AGESPAN Age Span Subgroups of populations based on age. (NCI) Yes

C66781 AGEU Age Unit Those units of time that are routinely used to express the age of a subject. No

C66786 COUNTRY Country A collective generic term that refers here to a wide variety of dependencies, areas of No special sovereignty, uninhabited islands, and other entities in addition to the traditional countries or independent states. (NCI)

C78731 DATEST Drug Accountability The name of the test for the drug accountability assessment. Yes Test Name

C78732 DATESTCD Drug Accountability The short name, or code, of the test for the drug accountability assessment. Yes Test Code

C66788 DICTNAM Dictionary Name A name given to a reference source that lists words and gives their meaning. (NCI) Yes

C99074 DIR Directionality CDISC terminology for anatomical location or specimen further detailing directionality. Yes

C66734 DOMAIN Domain Abbreviation A unique, 2-character domain code used in the regulatory submission process. The Yes domain abbreviation is used consistently throughout the submission, i.e. in the dataset name, as the value of the domain variable within the dataset, and as a prefix for most variable names in the dataset. (CDISC Glossary)

C74558 DSCAT Category for Classifications that describe and group pertinent events that occur throughout the conduct Yes Disposition Event of a clinical trial.

C90013 EGLEAD ECG Lead Terminology related to electrocardiogram lead names. Yes

C71151 EGMETHOD ECG Test Method Terminology codelist used with ECG Test Methods within CDISC. Yes

C71150 EGSTRESC ECG Result Terminology codelist used with ECG Findings and Abnormalities within CDISC. Yes

C71152 EGTEST ECG Test Name Terminology codelist used with ECG Test Names within CDISC. Yes

C71153 EGTESTCD ECG Test Code Terminology codelist used with ECG Tests within CDISC. Yes

C99079 EPOCH Epoch The name of the EPOCH. Yes

C66790 ETHNIC Ethnic Group A social group characterized by a distinctive social and cultural tradition maintained from Yes generation to generation, a common history and origin and a sense of identification with the group; members of the group have distinctive features in their way of life, shared experiences and often a common genetic heritage; these features may be reflected in their experience of health and disease. (NCI)

C78735 EVAL Evaluator The role that the individual or entity plays with respect to a specific situation or person. Yes

C71113 FREQ Frequency The terminology that includes terms pertaining to frequency within CDISC. Yes

C66726 FRM Pharmaceutical Dosage The form of the completed pharmaceutical product, e.g. tablet, capsule, injection, elixir, Yes Form suppository. Dosage form can have a significant effect on the onset, duration and intensity of the pharmacological action of a drug. A pharmaceutical dosage form controls the rate at which the drug is released into the biological fluids. This release rate affects its intrinsic absorption pattern and therefore, the bioavailability of the drug.

C66797 IECAT Category for A collection of criteria on which subjects are evaluated and that must be met by all study No Inclusion/Exclusion subjects. (NCI)

C99076 INTMODEL Intervention Model The trial design developed to compare treatment groups. Yes

C99078 INTTYPE Intervention Type The kind of product or procedure studied in a trial. No

C99073 LAT Laterality CDISC terminology for anatomical location or specimen further detailing the side(s) of Yes interest.

C67154 LBTEST Laboratory Test Name Terminology used for Laboratory Tests of the CDISC Standard Data Tabulation Model. Yes

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 1 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23

CDISC NCI Submission Codelist Code Value Codelist Name CDISC Definition Extensible

C65047 LBTESTCD Laboratory Test Code Terminology used for Laboratory Tests of the CDISC Standard Data Tabulation Model. Yes

C74456 LOC Anatomical Location Terminology codelist used for anatomical location within CDISC. Yes

C76348 MARISTAT Marital Status A demographic parameter indicating a person's current conjugal status. Yes

C96777 MEDEVAL Medical Evaluator The individual responsible for the medical assessment. Yes

C85492 METHOD Method Method is any technique or procedure (an action) that determines how an observation or Yes clinical finding was made.

C85491 MICROORG Microorganism Microorganisms, bacteria, fungi and other organisms. Yes

C85495 MSRESCAT Microbiology Used to categorize the result of a finding in a standard format. No Susceptibility Testing Result Category

C78738 NCF Never/Current/Former A classification of usage or experience that falls into three categories; never, current, or Yes Classification former.

C66727 NCOMPLT Completion/Reason for The status of the subject's completion of the study or a segment of the study, or the Yes Non-Completion reason the subject discontinued the study or segment of the study.

C66789 ND Not Done Indicates a task, process or examination that has either not been initiated or completed. No (NCI)

C88025 NEOPLASM Neoplasm Type The terminology that includes concepts relevant to benign or malignant tissue growth. Yes

C78736 NRIND Reference Range A description of the results relative to the normal or expected range of values. Yes Indicator

C66742 NY No Yes Response A term that is used to indicate a question with permissible values of yes/no/unknown/not No applicable.

C66768 OUT Outcome of Event A condition or event that is attributed to the adverse event and is the result or conclusion No of the adverse event. (NCI)

C95120 PHSPRP Physical Properties Test Terminology relevant to the test names that describe the physical characteristics of an Yes Name entity.

C95121 PHSPRPCD Physical Properties Test Terminology relevant to the test codes that describe the physical characteristics of an Yes Code entity.

C85493 PKPARM PK Parameters Parameters used to describe the time-concentration curve. Yes

C85839 PKPARMCD PK Parameters Code Parameter codes used to describe the time-concentration curve. Yes

C85494 PKUNIT PK Parameter Units of Units of measure needed for pharmacokinetic parameters. Yes Measure

C99075 PORTOT Portion/Totality Qualifier for anatomical location or specimen further detailing the portion or totality, Yes which means arrangement of, or apportioning of an entity.

C71148 POSITION Position Terminology codelist used with Body Position within CDISC. Yes

C74457 RACE Race Terminology codelist used to identify the race of an individual within the Clinical Data Yes Interchange Standards Consortium Study Data Tabulation Model.

C100130 RELSUB Relationship to Subject The relationship of a person to a study subject. Yes

C78737 RELTYPE Relationship Type The description of relationship types between a record or set of records. No

C66729 ROUTE Route of Administration The course by which a substance was administered in order to reach the site of action in Yes the body.

C96785 RSSTRESC Tumor Response Result The result of an assessment of tumor response to treatment or therapy. Yes

C96781 RSTEST Tumor Response Terminology relevant to the test names that describe an assessment of tumor response to Yes Assessment Test Name treatment or therapy.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 2 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23

CDISC NCI Submission Codelist Code Value Codelist Name CDISC Definition Extensible

C96782 RSTESTCD Tumor Response Terminology relevant to the test codes that describe an assessment of tumor response to Yes Assessment Test Code treatment or therapy.

C74559 SCCD Subject Characteristic A unique code representing each Subject Characteristic. Yes Code

C66731 SEX Sex The assemblage of physical properties or qualities by which male is distinguished from No female; the physical difference between male and female; the distinguishing peculiarity of male or female. (NCI)

C66732 SEXPOP Sex of Participants The specific sex, either male, female, or mixed of the subject group being studied. (NCI) No

C66733 SIZE Size The physical magnitude of something. (NCI) Yes

C76351 SKINCLAS Skin Classification A classification system used to categorize the sensitivity of a subject's skin to sunlight. Yes

C74561 SKINTYP Skin Type A distinctive characteristic of the skin marked by the amount of sebum secreted by Yes sebaceous glands.

C66783 SOC CDISC System Organ Terms at the highest level of the CDISC system organ class terminology. No Class

C78733 SPECCOND Specimen Condition The physical state or quality of a biological specimen. Yes

C78734 SPECTYPE Specimen Type The name and description of a biological specimen. Yes

C66728 STENRF Relation to Reference The relative relationship of a timepoint to a reference timepoint. No Period

C99077 STYPE Study Type Describes the role the study plays in determining the interventions a subject receives. No

C66735 TBLIND Trial Blinding Schema The name of a code list that contains terms to define the type of blinding for the trial. Yes (NCI)

C66785 TCNTRL Control Type Comparator against which the study treatment is evaluated (e.g., concurrent (placebo, no Yes treatment, dose-response, active), external (historical, published literature).

C66787 TDIGRP Diagnosis Group A grouping of individuals on the basis of a shared procedure or disease, or lack thereof Yes (e.g. healthy volunteers, type 2 diabetic subjects, subjects with renal cell cancer). Standardized naming systems are available that define the groups within which a subject should be placed. (NCI)

C66736 TINDTP Trial Indication Type The name of a code list that contains terms to define the type of trial, e.g. cure or Yes prevention. (NCI)

C66784 TOXGR Common Terminology A standard terminology developed to report adverse events occurring in cancer clinical No Criteria for Adverse trials. Common terminology criteria for adverse events (CTCAE) are used in study Events adverse event summaries and Investigational New Drug reports to the Food and Drug Administration. The CTCAE contain a grading scale for each adverse event term representing the severity of the event. (NCI)

C87162 TOXGR Common Terminology The version 4.0 standard terminology developed to report adverse events occurring in No Criteria for Adverse cancer clinical trials. Common terminology criteria for adverse events (CTCAE) are used Events V4.0 to study adverse event summaries and Investigational New Drug reports to the Food and Drug Administration. The CTCAE contain a grading scale for each adverse event term representing the severity of the event. (NCI)

C66737 TPHASE Trial Phase Clinical trials are broken into three or four phases: Phase I tests a new drug or treatment Yes for safety in a small group; Phase II expands the study to a larger group of people; Phase III expands the study to an even larger group of people to measure whether the treatment actually benefits patients, and whether its benefits exceed its risks; and Phase IV takes place after the drug or treatment has been licensed and marketed. (NCI)

C96778 TRTEST Oncology Tumor Terminology relevant to the test names that describe the measurement of a tumor. Yes Properties Test Name

C96779 TRTESTCD Oncology Tumor Terminology relevant to the test codes that describe the measurement of a tumor. Yes Properties Test Code

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 3 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23

CDISC NCI Submission Codelist Code Value Codelist Name CDISC Definition Extensible

C67152 TSPARM Trial Summary Individual characteristics of a clinical trial, e.g. description of trial design, trial blinding Yes Parameter Test Name schema, and primary objective of trial. (NCI)

C66738 TSPARMCD Trial Summary Individual characteristics of a clinical trial, e.g. description of trial design, trial blinding Yes Parameter Test Code schema, and primary objective of trial. (NCI)

C66739 TTYPE Trial Type The type of clinical trial performed e.g. efficacy, safety. (NCI) Yes

C96780 TUMIDENT Tumor Identification Terminology relevant to tumor identification results. Yes Results

C96783 TUTEST Tumor Identification Terminology relevant to the test names that describe tumor assessments for Yes Test Name identification purposes.

C96784 TUTESTCD Tumor Identification Terminology relevant to the test codes that describe tumor assessments for identification Yes Test Code purposes.

C71620 UNIT Unit Terminology codelist used for units within CDISC. Yes

C66770 VSRESU Units for Vital Signs The unit used to record and describe the result of a test investigating a vital sign. (NCI) Yes Results

C67153 VSTEST Vital Signs Test Name The name given to the test that analyzes a particular set of vital signs including Yes temperature, respiratory rate, heart beat (pulse), and blood pressure. (NCI)

C66741 VSTESTCD Vital Signs Test Code The name given to the test that analyzes a particular set of vital signs including Yes temperature, respiratory rate, heart beat (pulse), and blood pressure. (NCI)

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 4 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C66767 - ACN - Action Taken with Study Treatment Codelist extensible: No

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C49503 DOSE INCREASED An indication that a medication schedule was modified Dose Increased by addition; either by changing the frequency, strength or amount. (NCI)

C49504 DOSE NOT CHANGED An indication that a medication schedule was Dose Not Changed maintained. (NCI)

C49505 DOSE REDUCED An indication that a medication schedule was modified Dose Reduced by subtraction, either by changing the frequency, strength or amount. (NCI)

C49501 DRUG INTERRUPTED An indication that a medication schedule was modified Drug Interrupted by temporarily terminating a prescribed regimen of medication. (NCI)

C49502 DRUG WITHDRAWN An indication that a medication schedule was modified Drug Withdrawn through termination of a prescribed regimen of medication. (NCI)

C48660 NOT APPLICABLE NA; Not Determination of a value is not relevant in the current Not Applicable Applicable context. (NCI)

C17998 UNKNOWN U; Unknown Not known, not observed, not recorded, or refused. Unknown (NCI)

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 5 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C66769 - AESEV - Severity/Intensity Scale for Adverse Events Codelist extensible: No

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C41338 MILD Grade 1; 1 A type of adverse event that is usually transient and Mild Adverse Event may require only minimal treatment or therapeutic intervention. The event does not generally interfere with usual activities of daily living.

C41339 MODERATE Grade 2; 2 A type of adverse event that is usually alleviated with Moderate Adverse Event additional specific therapeutic intervention. The event interferes with usual activities of daily living, causing discomfort but poses no significant or permanent risk of harm to the research participant.

C41340 SEVERE Grade 3; 3 A type of adverse event that interrupts usual activities Severe Adverse Event of daily living, or significantly affects clinical status, or may require intensive therapeutic intervention.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 6 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C66780 - AGESPAN - Age Span Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C27954 ADOLESCENT (12-17 A juvenile between the onset of puberty and maturity; Adolescent YEARS) in the state of development between puberty and maturity. (NCI)

C49685 ADULT (18-65) A person from 18 years to 65 years of age. (NCI) Adult 18-65 Years Old

C49683 CHILDREN (2-11 YEARS) A person from 2 years to 11 years of age. (NCI) Children 2-11 Years Old

C16268 ELDERLY (> 65) An age group comprised by people 65 years of age and Elderly older. (NCI)

C49641 IN UTERO The period of time during which the embryo or fetus is In Utero present in the uterus of the female. Also describes the location of the embryo or fetus as being in the uterus in contrast to outside the uterus (ex utero). (NCI)

C49643 INFANT AND TODDLER (28 A person from 28 days to 23 months of age. (NCI) Infant And Toddler DAYS - 23 MONTHS)

C16731 NEWBORN (0-27 DAYS) An infant during the first month after birth. (NCI) Newborn

C49642 PRETERM NEWBORN An infant born prior to completion of the normal Preterm Newborn Infant INFANTS gestation period. (NCI)

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 7 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C66781 - AGEU - Age Unit Codelist extensible: No

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C25301 DAYS The time for Earth to make a complete rotation on its Day axis; ordinarily divided into twenty-four hours. This also refers to a specific day. (NCI)

C25529 HOURS Hour; hr A unit measure of time equal to 3,600 seconds or 60 Hour minutes. It is approximately 1/24 of a median day. (NCI)

C29846 MONTHS One of the 12 divisions of a year as determined by a Month calendar. It corresponds to the unit of time of approximately to one cycle of the moon's phases, about 30 days or 4 weeks. (NCI)

C29844 WEEKS Any period of seven consecutive days. (NCI) Week

C29848 YEARS The period of time that it takes for Earth to make a Year complete revolution around the sun, approximately 365 days; a specific one year period. (NCI)

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 8 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C66786 - COUNTRY - Country Codelist extensible: No

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C17884 ABW ARUBA Island in the Caribbean Sea, north of Venezuela. (NCI) Aruba

C16267 AFG AFGHANISTAN A country in Southern Asia, north and west of Pakistan, Afghanistan east of Iran. (NCI)

C16292 AGO ANGOLA A country in Southern Africa, bordering the South Angola Atlantic Ocean, between Namibia and Democratic Republic of the Congo. (NCI)

C20133 AIA ANGUILLA An island in the Caribbean Sea, east of Puerto Rico. Anguilla (NCI)

C44481 ALA ALAND An archipelago in the Baltic Sea at the entrance to the Aland Islands ISLANDS Gulf of Bothnia between Sweden and Finland. (NCI)

C16271 ALB ALBANIA A country in Southeastern Europe, bordering the Albania Adriatic Sea and Ionian Sea, between Greece and Serbia and Montenegro. (NCI)

C16289 AND ANDORRA A country in Southwestern Europe, between France and Andorra Spain. (NCI)

C16904 ANT NETHERLANDS A country in the Caribbean, comprising two island Netherlands Antilles ANTILLES groups in the Caribbean Sea - one includes Curacao and Bonaire north of Venezuela; the other is east of the Virgin Islands. (NCI)

C17232 ARE UNITED ARAB A country in the Middle East, bordering the Gulf of United Arab Emirates EMIRATES Oman and the Persian Gulf, between Oman and Saudi Arabia. (NCI)

C16305 ARG ARGENTINA A country in Southern South America, bordering the Argentina South Atlantic Ocean, between Chile and Uruguay. (NCI)

C16306 ARM ARMENIA A country in Southwestern Asia, east of Turkey. (NCI) Armenia

C17739 ASM AMERICAN A group of islands in the South Pacific Ocean, about American Samoa SAMOA half way between Hawaii and New Zealand. (NCI)

C18007 ATA ANTARCTICA The continent lying mostly south of the Antarctic Antarctica Circle. (NCI)

C20105 ATF FRENCH Islands in the southern Indian Ocean, south of Africa, French Southern Territories SOUTHERN about equidistant between Africa, Antarctica, and TERRITORIES Australia. (NCI)

C16303 ATG ANTIGUA AND Islands between the Caribbean Sea and the North Antigua and Barbuda BARBUDA Atlantic Ocean, east-southeast of Puerto Rico. (NCI)

C16311 AUS AUSTRALIA The continent between the Indian Ocean and the South Australia Pacific Ocean. (NCI)

C16312 AUT AUSTRIA A country in Central Europe, north of Italy and Austria Slovenia. (NCI)

C16316 AZE AZERBAIJAN A country in Southwestern Asia, bordering the Caspian Azerbaijan Sea, between Iran and Russia. (NCI)

C16371 BDI BURUNDI A country in Central Africa, east of Democratic Burundi Republic of the Congo. (NCI)

C16329 BEL BELGIUM A country in Western Europe, bordering the North Sea, Belgium between France and the Netherlands. (NCI)

C16333 BEN BENIN A country in Western Africa, bordering the North Benin REPUBLIC Atlantic Ocean, between Nigeria and Togo. (NCI)

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 9 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C66786 - COUNTRY - Country Codelist extensible: No

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C16369 BFA BURKINA FASO A country in Western Africa, north of Ghana. (NCI) Burkina Faso

C16323 BGD BANGLADESH A country in Southern Asia, bordering the Bay of Bangladesh Bengal, between Burma and India. (NCI)

C16368 BGR BULGARIA A country in Southeastern Europe, bordering the Black Bulgaria Sea, between Romania and Turkey. (NCI)

C16322 BHR BAHRAIN An archipelago in the Persian Gulf, east of Saudi Bahrain Arabia. (NCI)

C16321 BHS BAHAMAS A chain of islands in the North Atlantic Ocean, Bahamas southeast of Florida. (NCI)

C16361 BIH BOSNIA-HERZE A country in Southeastern Europe, bordering the Bosnia and Herzegovina GOVINA Adriatic Sea and Croatia. (NCI)

C83609 BLM SAINT An island in the Caribbean sea, between Saint Martin Saint Barthelemy BARTHELEMY and Saint Kitts and Nevis. (NCI)

C16372 BLR BELARUS A country in Eastern Europe, east of Poland. (NCI) Belarus

C16331 BLZ BELIZE A country in Central America, bordering the Caribbean Belize Sea, between Guatemala and Mexico. (NCI)

C16334 BMU BERMUDA A group of islands in the North Atlantic Ocean, east of Bermuda South Carolina. (NCI)

C16359 BOL BOLIVIA A country in Central South America, southwest of Bolivia Brazil. (NCI)

C16364 BRA BRAZIL A country in Eastern South America, bordering the Brazil Atlantic Ocean. (NCI)

C16324 BRB BARBADOS An island between the Caribbean Sea and the North Barbados Atlantic Ocean, northeast of Venezuela. (NCI)

C16367 BRN BRUNEI A country in Southeastern Asia, bordering the South Brunei Darussalam China Sea and Malaysia. (NCI)

C16336 BTN BHUTAN A country in Southern Asia, between China and India. Bhutan (NCI)

C20104 BVT BOUVET An island in the South Atlantic Ocean, south-southwest Bouvet Island ISLAND of the Cape of Good Hope (South Africa). (NCI)

C16363 BWA BOTSWANA A country in Southern Africa, north of South Africa. Botswana (NCI)

C16409 CAF CENTRAL A country in Central Africa, north of Democratic Central African Republic AFRICAN Republic of the Congo. (NCI) REPUBLIC

C16380 CAN CANADA A country in Northern North America, bordering the Canada North Atlantic Ocean on the east, North Pacific Ocean on the west, and the Arctic Ocean on the north, north of the conterminous US. (NCI)

C16445 CCK COCOS A group of islands in the Indian Ocean, south of Cocos (Keeling) Islands (KEELING) Indonesia, about halfway from Australia to Sri Lanka. ISLANDS (NCI)

C17181 CHE SWITZERLAND A country in Central Europe, east of France, north of Switzerland Italy. (NCI)

C16427 CHL CHILE A country in Southern South America, bordering the Chile South Atlantic Ocean and South Pacific Ocean, between Argentina and Peru. (NCI)

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 10 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C66786 - COUNTRY - Country Codelist extensible: No

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C16428 CHN CHINA A country in Eastern Asia, bordering the East China China Sea, Korea Bay, Yellow Sea, and South China Sea, between North Korea and Vietnam. (NCI)

C16762 CIV COTE D'IVOIRE A country in Western Africa, bordering the North Cote d'Ivoire Atlantic Ocean, between Ghana and Liberia. (NCI)

C16379 CMR CAMEROON A country in Western Africa, bordering the Bight of Cameroon Biafra, between Equatorial Guinea and Nigeria. (NCI)

C17266 COD DEMOCRATIC A country in Central Africa, northeast of Angola. Congo, the Democratic Republic of REPUBLIC OF (NCI) the THE CONGO

C16467 COG CONGO A country in Western Africa, bordering the South Congo Atlantic Ocean, between Angola and Gabon. (NCI)

C16469 COK COOK ISLANDS A group of islands in the South Pacific Ocean, about Cook Islands one-half of the way from Hawaii to New Zealand. (NCI)

C16449 COL COLOMBIA A country in Northern South America, bordering the Colombia Caribbean Sea, between Panama and Venezuela, and bordering the North Pacific Ocean, between Ecuador and Panama. (NCI)

C16458 COM COMOROS A group of islands in the Mozambique Channel, about Comoros two-thirds of the way between northern Madagascar and northern Mozambique. (NCI)

C16382 CPV CAPE VERDE A group of islands in the North Atlantic Ocean, west of Cape Verde Senegal. (NCI)

C16470 CRI COSTA RICA A country in Central America, bordering both the Costa Rica Caribbean Sea and the North Pacific Ocean, between Nicaragua and Panama. (NCI)

C16477 CUB CUBA An island between the Caribbean Sea and the North Cuba Atlantic Ocean, 150 km south of Key West, Florida. (NCI)

C44482 CXR CHRISTMAS An Australian-administered island in the eastern Indian Christmas Island ISLAND Ocean south of Java, Indonesia. (NCI)

C16391 CYM CAYMAN An island group in the Caribbean Sea, nearly one-half Cayman Islands ISLANDS of the way from Cuba to Honduras. (NCI)

C16480 CYP CYPRUS An island in the Mediterranean Sea, south of Turkey. Cyprus (NCI)

C17668 CZE CZECH A country in Central Europe, southeast of Germany. Czech Republic REPUBLIC (NCI)

C16636 DEU GERMANY A country in Central Europe, bordering the Baltic Sea Germany and the North Sea, between the Netherlands and Poland, south of Denmark. (NCI)

C16506 DJI DJIBOUTI A country in Eastern Africa, bordering the Gulf of Djibouti Aden and the Red Sea, between Eritrea and Somalia. (NCI)

C16519 DMA DOMINICA An island between the Caribbean Sea and the North Dominica Atlantic Ocean, about one-half of the way from Puerto Rico to Trinidad and Tobago. (NCI)

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 11 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C66786 - COUNTRY - Country Codelist extensible: No

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C16496 DNK DENMARK A country in Northern Europe, bordering the Baltic Denmark Sea and the North Sea, on a peninsula north of Germany (Jutland); also includes two major islands (Sjaelland and Fyn). (NCI)

C16520 DOM DOMINICAN A country comprising the eastern two-thirds of the Dominican Republic REPUBLIC island of Hispaniola, between the Caribbean Sea and the North Atlantic Ocean, east of Haiti. (NCI)

C16274 DZA ALGERIA A country in Northern Africa, bordering the Algeria Mediterranean Sea, between Morocco and Tunisia. (NCI)

C16528 ECU ECUADOR A country in Western South America, bordering the Ecuador Pacific Ocean at the Equator, between Colombia and Peru. (NCI)

C16530 EGY EGYPT A country in Northern Africa, bordering the Egypt Mediterranean Sea, between Libya and the Gaza Strip. (NCI)

C16558 ERI ERITREA A country in Eastern Africa, bordering the Red Sea, Eritrea between Djibouti and Sudan. (NCI)

C20113 ESH WESTERN A country in Northern Africa, bordering the North Western Sahara SAHARA Atlantic Ocean, between Mauritania and Morocco. (NCI)

C17152 ESP SPAIN A country in Southwestern Europe, bordering the Bay Spain of Biscay, Mediterranean Sea, North Atlantic Ocean, and Pyrenees Mountains, southwest of France. (NCI)

C16562 EST ESTONIA A country in Eastern Europe, bordering the Baltic Sea Estonia and Gulf of Finland, between Latvia and Russia. (NCI)

C16563 ETH ETHIOPIA A country in Eastern Africa, west of Somalia. (NCI) Ethiopia

C16584 FIN FINLAND A country in Northern Europe, bordering the Baltic Finland Sea, Gulf of Bothnia, and Gulf of Finland, between Sweden and Russia. (NCI)

C16582 FJI FIJI An island group in the South Pacific Ocean, about Fiji two-thirds of the way from Hawaii to New Zealand. (NCI)

C17954 FLK FALKLAND Islands in the South Atlantic Ocean, east of southern Falkland Islands (Malvinas) ISLANDS Argentina. (NCI)

C16592 FRA FRANCE A country in Western Europe, bordering the Bay of France Biscay and English Channel, between Belgium and Spain, southeast of the UK; bordering the Mediterranean Sea, between Italy and Spain. (NCI)

C16573 FRO FAROE An island group between the Norwegian Sea and the Faroe Islands ISLANDS North Atlantic Ocean, about one-half of the way from Iceland to Norway. (NCI)

C17881 FSM MICRONESIA, An island group in the North Pacific Ocean, about Micronesia, Federated States of FEDERATED three-quarters of the way from Hawaii to Indonesia. STATES OF (NCI)

C16596 GAB GABON A country in Western Africa, bordering the Atlantic Gabon Ocean at the Equator, between Republic of the Congo and Equatorial Guinea. (NCI)

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 12 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C66786 - COUNTRY - Country Codelist extensible: No

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C17233 GBR UNITED A country in Western Europe, comprising islands, United Kingdom KINGDOM including the northern one-sixth of the island of Ireland, between the North Atlantic Ocean and the North Sea, northwest of France. (NCI)

C16634 GEO GEORGIA A country in Southwestern Asia, bordering the Black Georgia Sea, between Turkey and Russia. (NCI)

C64375 GGY GUERNSEY The island of Guernsey and the other Channel Islands Guernsey represent the last remnants of the medieval Dukedom of Normandy, which held sway in both France and England. Guernsey is a British crown dependency, but is not part of the UK. (NCI)

C26330 GHA GHANA A country in Western Africa, bordering the Gulf of Ghana Guinea, between Cote d'Ivoire and Togo. (NCI)

C16638 GIB GIBRALTAR A dependency in Southwestern Europe, bordering the Gibraltar Strait of Gibraltar, on the southern coast of Spain. (NCI)

C16655 GIN GUINEA A country in Western Africa, bordering the North Guinea Atlantic Ocean, between Guinea-Bissau and Sierra Leone. (NCI)

C16651 GLP GUADELOUPE Islands in the eastern Caribbean Sea, southeast of Guadeloupe Puerto Rico. (NCI)

C16598 GMB GAMBIA A country in Western Africa, bordering the North Gambia Atlantic Ocean and Senegal. (NCI)

C16656 GNB GUINEA-BISSA A country in Western Africa, bordering the North Guinea-Bissau U Atlantic Ocean, between Guinea and Senegal. (NCI)

C16557 GNQ EQUATORIAL A country in Western Africa, bordering the Bight of Equatorial Guinea GUINEA Biafra, between Cameroon and Gabon; composed of a mainland portion and five inhabited islands. (NCI)

C16645 GRC GREECE A country in Southern Europe, bordering the Aegean Greece Sea, Ionian Sea, and the Mediterranean Sea, between Albania and Turkey. (NCI)

C16647 GRD GRENADA An island between the Caribbean Sea and Atlantic Grenada Ocean, north of Trinidad and Tobago. (NCI)

C16646 GRL GREENLAND An island between the Arctic Ocean and the North Greenland Atlantic Ocean, northeast of Canada. (NCI)

C16654 GTM GUATEMALA A country in Central America, bordering the Caribbean Guatemala Sea, between Honduras and Belize and bordering the North Pacific Ocean, between El Salvador and Mexico. (NCI)

C16593 GUF FRENCH A country in Northern South America, bordering the French Guiana GUIANA North Atlantic Ocean, between Brazil and Suriname. (NCI)

C16652 GUM GUAM Island in the North Pacific Ocean, about three-quarters Guam of the way from Hawaii to the Philippines. (NCI)

C16657 GUY GUYANA A country in Northern South America, bordering the Guyana North Atlantic Ocean, between Suriname and Venezuela. (NCI)

C16695 HKG HONG KONG A special administrative region of China, bordering the Hong Kong South China Sea and China. (NCI)

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 13 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C66786 - COUNTRY - Country Codelist extensible: No

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C20106 HMD HEARD ISLAND Islands in the Indian Ocean, about two-thirds of the way Heard Island and McDonald Islands AND from Madagascar to Antarctica. (NCI) MCDONALD ISLANDS

C16694 HND HONDURAS A country in Central America, bordering the Caribbean Honduras Sea, between Guatemala and Nicaragua and bordering the North Pacific Ocean, between El Salvador and Nicaragua. (NCI)

C16474 HRV CROATIA A country in Southeastern Europe, bordering the Croatia Adriatic Sea, between Bosnia and Herzegovina and Slovenia. (NCI)

C16660 HTI HAITI A country comprising the western one-third of the Haiti island of Hispaniola, between the Caribbean Sea and the North Atlantic Ocean, west of the Dominican Republic. (NCI)

C16699 HUN HUNGARY A country in Central Europe, northwest of Romania. Hungary (NCI)

C16728 IDN INDONESIA A country in Southeastern Asia, comprising the Indonesia archipelago between the Indian Ocean and the Pacific Ocean. (NCI)

C44480 IMN ISLE OF MAN An island in the Irish Sea, between Great Britain and Isle of Man Ireland. (NCI)

C16727 IND INDIA A country in Southern Asia, bordering the Arabian Sea India and the Bay of Bengal, between Burma and Pakistan. (NCI)

C16365 IOT BRITISH An archipelago in the Indian Ocean, about one-half the British Indian Ocean Territory INDIAN OCEAN way from Africa to Indonesia. (NCI) TERRITORY

C16757 IRL IRELAND A country in Western Europe, occupying five-sixths of Ireland the island of Ireland in the North Atlantic Ocean, west of Great Britain. (NCI)

C16755 IRN IRAN A country in the Middle East, bordering the Gulf of Iran, Islamic Republic of Oman, the Persian Gulf, and the Caspian Sea, between Iraq and Pakistan. (NCI)

C16756 IRQ IRAQ A country in the Middle East, bordering the Persian Iraq Gulf, between Iran and Kuwait. (NCI)

C16704 ISL ICELAND A country in Northern Europe, island between the Iceland Greenland Sea and the North Atlantic Ocean, northwest of the UK. (NCI)

C16760 ISR ISRAEL A country in the Middle East, bordering the Israel Mediterranean Sea, between Egypt and Lebanon. (NCI)

C16761 ITA ITALY A country in Southern Europe, occupying a peninsula Italy extending into the central Mediterranean Sea, northeast of Tunisia. (NCI)

C16763 JAM JAMAICA An island in the Caribbean Sea, south of Cuba. (NCI) Jamaica

C64374 JEY JERSEY Jersey and the other Channel Islands represent the last Jersey remnants of the medieval Dukedom of Normandy that held sway in both France and England. Jersey is a British crown dependency, but is not part of the UK. (NCI)

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 14 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C66786 - COUNTRY - Country Codelist extensible: No

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C16765 JOR JORDAN A country in the Middle East, northwest of Saudi Jordan Arabia. (NCI)

C16764 JPN JAPAN A country in Eastern Asia, occupying an island chain Japan between the North Pacific Ocean and the Sea of Japan, east of the Korean Peninsula. (NCI)

C20107 KAZ KAZAKHSTAN A country in Central Asia, northwest of China. (NCI) Kazakhstan

C16769 KEN KENYA A country in Eastern Africa, bordering the Indian Kenya Ocean, between Somalia and Tanzania. (NCI)

C16771 KGZ KYRGYZSTAN A country in Central Asia, west of China. (NCI) Kyrgyzstan

C16378 KHM CAMBODIA A country in Southeastern Asia, bordering the Gulf of Cambodia Thailand, between Thailand, Vietnam, and Laos. (NCI)

C16639 KIR KIRIBATI A group of 33 coral atolls in the Pacific Ocean, Kiribati straddling the equator; the capital Tarawa is about one-half of the way from Hawaii to Australia. (NCI)

C17885 KNA SAINT KITTS Islands in the Caribbean Sea, about one-third of the Saint Kitts and Nevis AND NEVIS way from Puerto Rico to Trinidad and Tobago. (NCI)

C16774 KOR SOUTH KOREA A country in Eastern Asia, occupying the southern half Korea, Republic of of the Korean Peninsula, bordering the Sea of Japan and the Yellow Sea. (NCI)

C16775 KWT KUWAIT A country in the Middle East, bordering the Persian Kuwait Gulf, between Iraq and Saudi Arabia. (NCI)

C16780 LAO LAO PEOPLE'S A country in Southeastern Asia, northeast of Thailand, Lao People's Democratic Republic DEMOCRATIC west of Vietnam. (NCI) REPUBLIC

C16784 LBN LEBANON A country in the Middle East, bordering the Lebanon Mediterranean Sea, between Israel and Syria. (NCI)

C16791 LBR LIBERIA A country in Western Africa, bordering the North Liberia Atlantic Ocean, between Cote d'Ivoire and Sierra Leone. (NCI)

C16793 LBY LIBYAN ARAB A country in Northern Africa, bordering the Libyan Arab Jamahiriya JAMAHIRIYA Mediterranean Sea, between Egypt and Tunisia. (NCI)

C17113 LCA SAINT LUCIA A country in the Caribbean, occupying an island Saint Lucia between the Caribbean Sea and North Atlantic Ocean, north of Trinidad and Tobago. (NCI)

C16794 LIE LIECHTENSTEI A country in Central Europe, between Austria and Liechtenstein N Switzerland. (NCI)

C17163 LKA SRI LANKA A country in Southern Asia, occupying an island in the Sri Lanka Indian Ocean, south of India. (NCI)

C16787 LSO LESOTHO A country in Southern Africa, an enclave of South Lesotho Africa. (NCI)

C16799 LTU LITHUANIA A country in Eastern Europe, bordering the Baltic Sea, Lithuania between Latvia and Russia. (NCI)

C16803 LUX LUXEMBOURG A country in Western Europe, between France, Luxembourg Belgium, and Germany. (NCI)

C16783 LVA LATVIA A country in Eastern Europe, bordering the Baltic Sea, Latvia between Estonia and Lithuania. (NCI)

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 15 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C66786 - COUNTRY - Country Codelist extensible: No

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C16807 MAC MACAO A country in Eastern Asia, bordering the South China Macao Sea and China. (NCI)

C83610 MAF SAINT MARTIN, An island in the Caribbean sea, between Anguilla and Saint Martin, French FRENCH Saint Barthelemy. (NCI)

C16878 MAR MOROCCO A country in Northern Africa, bordering the North Morocco Atlantic Ocean and the Mediterranean Sea, between Algeria and Western Sahara. (NCI)

C16874 MCO MONACO A country in Western Europe, bordering the Monaco Mediterranean Sea on the southern coast of France, near the border with Italy. (NCI)

C16871 MDA MOLDOVA, A country in Eastern Europe, northeast of Romania. Moldova, Republic of REPUBLIC OF (NCI)

C16808 MDG MADAGASCAR A country in Southern Africa, occupying an island in Madagascar the Indian Ocean, east of Mozambique. (NCI)

C16815 MDV MALDIVES A country in Southern Asia, occupying a group of Maldives atolls in the Indian Ocean, south-southwest of India. (NCI)

C16850 MEX MEXICO A country in Central America, bordering the Caribbean Mexico Sea and the Gulf of Mexico, between Belize and the US and bordering the North Pacific Ocean, between Guatemala and the US. (NCI)

C16822 MHL MARSHALL A group of atolls and reefs in the North Pacific Ocean, Marshall Islands ISLANDS about one-half of the way from Hawaii to Australia. (NCI)

C17654 MKD REPUBLIC OF A country in Southeastern Europe, north of Greece. Macedonia, the Former Yugoslav MACEDONIA (NCI) Republic of

C16816 MLI MALI A country in Western Africa, southwest of Algeria. Mali (NCI)

C16817 MLT MALTA A country in Southern Europe, occupying islands in the Malta Mediterranean Sea, south of Sicily (Italy). (NCI)

C16370 MMR MYANMAR A country in Southeastern Asia, bordering the Myanmar Andaman Sea and the Bay of Bengal, between Bangladesh and Thailand. (NCI)

C64378 MNE MONTENEGRO A republic in Southeastern Europe, bordering the Montenegro Adriatic Sea, between Albania and Bosnia and Herzegovina. Formerly part of Serbia and Montenegro (Federation Republic of Yugoslavia). (NCI)

C16875 MNG MONGOLIA A country in Northern Asia, between China and Russia. Mongolia (NCI)

C17882 MNP NORTHERN A country in the Pacific, comprising islands in the Northern Mariana Islands MARIANA North Pacific Ocean, about three-quarters of the way ISLANDS from Hawaii to the Philippines. (NCI)

C16882 MOZ MOZAMBIQUE A country in Southern Africa, bordering the Mozambique Mozambique Channel, between South Africa and Tanzania. (NCI)

C16826 MRT MAURITANIA A country in Northern Africa, bordering the North Mauritania Atlantic Ocean, between Senegal and Western Sahara. (NCI)

C16876 MSR MONTSERRAT A country in the Caribbean, occupying an island in the Montserrat Caribbean Sea, southeast of Puerto Rico. (NCI)

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 16 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C66786 - COUNTRY - Country Codelist extensible: No

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C16823 MTQ MARTINIQUE An island in the Caribbean Sea, north of Trinidad and Martinique Tobago. (NCI)

C16827 MUS MAURITIUS A country in Southern Africa, occupying an island in Mauritius the Indian Ocean, east of Madagascar. (NCI)

C16813 MWI MALAWI A country in Southern Africa, east of Zambia. (NCI) Malawi

C16814 MYS MALAYSIA A country in Southeastern Asia, occupying a peninsula Malaysia and the northern one-third of the island of Borneo, bordering Indonesia and the South China Sea, south of Vietnam. (NCI)

C16828 MYT MAYOTTE A country in Southern Africa, occupying an island in Mayotte the Mozambique Channel, about one-half of the way from northern Madagascar to northern Mozambique. (NCI)

C16891 NAM NAMIBIA A country in Southern Africa, bordering the South Namibia Atlantic Ocean, between Angola and South Africa. (NCI)

C16913 NCL NEW A country in the Pacific, comprised of islands in the New Caledonia CALEDONIA South Pacific Ocean, east of Australia. (NCI)

C16916 NER NIGER A country in Western Africa, southeast of Algeria. Niger (NCI)

C16919 NFK NORFOLK A country in the Pacific, occupying an island in the Norfolk Island ISLAND South Pacific Ocean, east of Australia. (NCI)

C16917 NGA NIGERIA A country in Western Africa, bordering the Gulf of Nigeria Guinea, between Benin and Cameroon. (NCI)

C16915 NIC NICARAGUA A country in Central America, bordering both the Nicaragua Caribbean Sea and the North Pacific Ocean, between Costa Rica and Honduras. (NCI)

C16918 NIU NIUE A country in the Pacific, occupying an island in the Niue South Pacific Ocean, east of Tonga. (NCI)

C16903 NLD NETHERLANDS A country in Western Europe, bordering the North Sea, Netherlands between Belgium and Germany. (NCI)

C16920 NOR NORWAY A country in Northern Europe, bordering the North Sea Norway and the North Atlantic Ocean, west of Sweden. (NCI)

C16901 NPL NEPAL A country in Southern Asia, between China and India. Nepal (NCI)

C16896 NRU NAURU A country in Oceania, occupying an island in the South Nauru Pacific Ocean, south of the Marshall Islands. (NCI)

C16914 NZL NEW ZEALAND A country in the Pacific, comprised of islands in the New Zealand South Pacific Ocean, southeast of Australia. (NCI)

C16933 OMN OMAN A country in the Middle East, bordering the Arabian Oman Sea, Gulf of Oman, and Persian Gulf, between Yemen and the United Arab Emirates. (NCI)

C16949 PAK PAKISTAN A country in Southern Asia, bordering the Arabian Sea, Pakistan between India on the east and Iran and Afghanistan on the west and China in the north. (NCI)

C16951 PAN PANAMA A country in Central America, bordering both the Panama Caribbean Sea and the North Pacific Ocean, between Colombia and Costa Rica. (NCI)

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 17 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C66786 - COUNTRY - Country Codelist extensible: No

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C16993 PCN PITCAIRN A country in the Pacific, comprised of islands in the Pitcairn South Pacific Ocean, about midway between Peru and New Zealand. (NCI)

C16972 PER PERU A country in Western South America, bordering the Peru South Pacific Ocean, between Chile and Ecuador. (NCI)

C16978 PHL PHILIPPINES A country in Southeastern Asia, comprised of an Philippines archipelago between the Philippine Sea and the South China Sea, east of Vietnam. (NCI)

C17733 PLW PALAU A country in the Pacific, comprising a group of islands Palau in the North Pacific Ocean, southeast of the Philippines. (NCI)

C16952 PNG PAPUA NEW A country in Southeastern Asia, comprising a group of Papua New Guinea GUINEA islands and including the eastern half of the island of New Guinea, between the Coral Sea and the South Pacific Ocean, east of Indonesia. (NCI)

C17002 POL POLAND A country in Central Europe, east of Germany. (NCI) Poland

C17043 PRI PUERTO RICO An island between the Caribbean Sea and the North Puerto Rico Atlantic Ocean, east of the Dominican Republic. (NCI)

C16773 PRK NORTH KOREA A country in Eastern Asia, occupying the northern half Korea, Democratic People's of the Korean Peninsula, bordering the Korea Bay and Republic of the Sea of Japan, between China and South Korea. (NCI)

C17006 PRT PORTUGAL A country in Southwestern Europe, bordering the Portugal North Atlantic Ocean, west of Spain. (NCI)

C16953 PRY PARAGUAY A country in Central South America, northeast of Paraguay Argentina. (NCI)

C20110 PSE PALESTINIAN A collective name for the West Bank and the Gaza Palestinian Territory, Occupied TERRITORY, Strip, two territories in Palestine. (NCI) OCCUPIED

C16594 PYF FRENCH An archipelago in the South Pacific Ocean, about French Polynesia POLYNESIA one-half of the way from South America to Australia. (NCI)

C17045 QAT QATAR A country in the Middle East, occupying a peninsula Qatar bordering the Persian Gulf and Saudi Arabia. (NCI)

C17095 REU REUNION A country in Southern Africa, occupying an island in Reunion the Indian Ocean, east of Madagascar. (NCI)

C17108 ROU ROMANIA A country in Southeastern Europe, bordering the Black Romania Sea, between Bulgaria and Ukraine. (NCI)

C17111 RUS RUSSIAN A country in Northern Asia (that part west of the Urals Russian Federation FEDERATION is sometimes included with Europe), bordering the Arctic Ocean, between Europe and the North Pacific Ocean. (NCI)

C17112 RWA RWANDA A country in Central Africa, east of Democratic Rwanda Republic of the Congo. (NCI)

C17117 SAU SAUDI ARABIA A country in the Middle East, bordering the Persian Saudi Arabia Gulf and the Red Sea, north of Yemen. (NCI)

C17170 SDN SUDAN A country in Northern Africa, bordering the Red Sea, Sudan between Egypt and Eritrea. (NCI)

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 18 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C66786 - COUNTRY - Country Codelist extensible: No

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C17121 SEN SENEGAL A country in Western Africa, bordering the North Senegal Atlantic Ocean, between Guinea-Bissau and Mauritania. (NCI)

C17134 SGP SINGAPORE A country in Southeastern Asia, comprised of islands Singapore between Malaysia and Indonesia. (NCI)

C20111 SGS SOUTH A group of islands in the South Atlantic Ocean, east of South Georgia and the South GEORGIA AND the tip of South America. (NCI) Sandwich Islands THE SOUTH SANDWICH ISLANDS

C17164 SHN SAINT HELENA Islands in the South Atlantic Ocean, about midway Saint Helena between South America and Africa. (NCI)

C17178 SJM SVALBARD Islands between the Arctic Ocean, Barents Sea, Svalbard and Jan Mayen AND JAN Greenland Sea, and Norwegian Sea, northeast of MAYEN Iceland and north of Norway. (NCI)

C17148 SLB SOLOMON A group of islands in the South Pacific Ocean, east of Solomon Islands ISLANDS Papua New Guinea. (NCI)

C17130 SLE SIERRA LEONE A country in Western Africa, bordering the North Sierra Leone Atlantic Ocean, between Guinea and Liberia. (NCI)

C16532 SLV EL SALVADOR A country in Central America, bordering the North El Salvador Pacific Ocean, between Guatemala and Honduras. (NCI)

C17115 SMR SAN MARINO A country in Southern Europe, an enclave in central San Marino Italy. (NCI)

C17149 SOM SOMALIA A country in Eastern Africa, bordering the Gulf of Somalia Aden and the Indian Ocean, east of Ethiopia. (NCI)

C17165 SPM SAINT PIERRE A country in Northern North America, comprised of Saint Pierre and Miquelon AND islands in the North Atlantic Ocean, south of MIQUELON Newfoundland (Canada). (NCI)

C64377 SRB SERBIA A republic in Southeastern Europe, bordering the Serbia Adriatic Sea, between Albania and Bosnia and Herzegovina. Formerly part of Serbia and Montenegro (Federation Republic of Yugoslavia). (NCI)

C17116 STP SAO TOME A country in Western Africa, comprised of islands in Sao Tome and Principe AND PRINCIPE the Gulf of Guinea, straddling the Equator, west of Gabon. (NCI)

C17175 SUR SURINAME A country in Northern South America, bordering the Suriname North Atlantic Ocean, between French Guiana and Guyana. (NCI)

C17669 SVK SLOVAKIA A country in Central Europe, south of Poland. (NCI) Slovakia

C17138 SVN SLOVENIA A country in Central Europe, bordering the Adriatic Slovenia Sea, between Austria and Croatia. (NCI)

C17180 SWE SWEDEN A country in Northern Europe, bordering the Baltic Sweden Sea, Gulf of Bothnia, Kattegat, and Skagerrak, between Finland and Norway. (NCI)

C17179 SWZ SWAZILAND A country in Southern Africa, between Mozambique Swaziland and South Africa. (NCI)

C17129 SYC SEYCHELLES A country in Eastern Africa, comprised of a group of Seychelles islands in the Indian Ocean, northeast of Madagascar. (NCI)

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 19 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C66786 - COUNTRY - Country Codelist extensible: No

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C17182 SYR SYRIAN ARAB A country in the Middle East, bordering the Syrian Arab Republic REPUBLIC Mediterranean Sea, between Lebanon and Turkey. (NCI)

C17224 TCA TURKS AND Two island groups in the North Atlantic Ocean, Turks and Caicos Islands CAICOS southeast of The Bahamas. (NCI) ISLANDS

C16412 TCD CHAD A country in Central Africa, south of Libya. (NCI) Chad

C17202 TGO TOGO A country in Western Africa, bordering the Bight of Togo Benin, between Benin and Ghana. (NCI)

C17192 THA THAILAND A country in Southeastern Asia, bordering the Thailand Andaman Sea and the Gulf of Thailand, southeast of Burma. (NCI)

C17183 TJK TAJIKISTAN A country in Central Asia, west of China. (NCI) Tajikistan

C17704 TKL TOKELAU A group of three atolls in the South Pacific Ocean, Tokelau about one-half of the way from Hawaii to New Zealand. (NCI)

C17223 TKM TURKMENISTA A country in Central Asia, bordering the Caspian Sea, Turkmenistan N between Iran and Kazakhstan. (NCI)

C17200 TLS TIMOR-LESTE A country in Southeastern Asia, northwest of Australia Timor-Leste in the Lesser Sunda Islands at the eastern end of the Indonesian archipelago. East Timor includes the eastern half of the island of Timor, the Oecussi (Ambeno) region on the northwest portion of the island of Timor, and the islands of Pulau Atauro and Pulau Jaco. (NCI)

C17205 TON TONGA An archipelago in the South Pacific Ocean, about Tonga two-thirds of the way from Hawaii to New Zealand. (NCI)

C17217 TTO TRINIDAD AND Islands between the Caribbean Sea and the North Trinidad and Tobago TOBAGO Atlantic Ocean, northeast of Venezuela. (NCI)

C17221 TUN TUNISIA A country in Northern Africa, bordering the Tunisia Mediterranean Sea, between Algeria and Libya. (NCI)

C17222 TUR TURKEY A country in southeastern Europe and southwestern Turkey Asia (that portion of Turkey west of the Bosporus is geographically part of Europe), bordering the Black Sea, between Bulgaria and Georgia, and bordering the Aegean Sea and the Mediterranean Sea, between Greece and Syria. (NCI)

C17225 TUV TUVALU An island group consisting of nine coral atolls in the Tuvalu South Pacific Ocean, about one-half of the way from Hawaii to Australia. (NCI)

C17184 TWN TAIWAN A group of islands bordering the East China Sea, Taiwan, Province of China Philippine Sea, South China Sea, and Taiwan Strait, north of the Philippines, off the southeastern coast of China. (NCI)

C17185 TZA TANZANIA, A country in Eastern Africa, bordering the Indian Tanzania, United Republic of UNITED Ocean, between Kenya and Mozambique. (NCI) REPUBLIC OF

C17228 UGA UGANDA A country in Eastern Africa, west of Kenya. (NCI) Uganda

C17229 UKR UKRAINE A country in Eastern Europe, bordering the Black Sea, Ukraine between Poland and Russia. (NCI)

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 20 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C66786 - COUNTRY - Country Codelist extensible: No

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C20112 UMI UNITED The U.S. Minor Outlying Islands consist of Baker United States Minor Outlying Islands STATES MINOR Island, Howland Island, Jarvis Island, Johnston Atoll, OUTLYING Kingman Reef, Midway Island, Navassa Island, Palmyra ISLANDS Atoll, and Wake Island (Wake Atoll). (NCI)

C17244 URY URUGUAY A country in Southern South America, bordering the Uruguay South Atlantic Ocean, between Argentina and Brazil. (NCI)

C17234 USA UNITED A country in North America, bordering both the North United States STATES Atlantic Ocean and the North Pacific Ocean, between Canada and Mexico. (NCI)

C17246 UZB UZBEKISTAN A country in Central Asia, north of Afghanistan. (NCI) Uzbekistan

C17249 VAT VATICAN CITY An enclave of Rome (Italy). (NCI) Holy See (Vatican City State) STATE

C17114 VCT SAINT A country in the Caribbean, comprised of islands in the Saint Vincent and the Grenadines VINCENT AND Caribbean Sea, north of Trinidad and Tobago. (NCI) THE GRENADINES

C17250 VEN VENEZUELA A country in Northern South America, bordering the Venezuela Caribbean Sea and the North Atlantic Ocean, between Colombia and Guyana. (NCI)

C17653 VGB VIRGIN Islands between the Caribbean Sea and the North Virgin Islands, British ISLANDS, Atlantic Ocean, east of Puerto Rico. (NCI) BRITISH

C17255 VIR VIRGIN Islands between the Caribbean Sea and the North Virgin Islands, U.S. ISLANDS, U.S. Atlantic Ocean, east of Puerto Rico. (NCI)

C17252 VNM VIETNAM A country in Southeastern Asia, bordering the Gulf of Viet Nam Thailand, Gulf of Tonkin, and South China Sea, alongside China, Laos, and Cambodia. (NCI)

C17247 VUT VANUATU A group of islands in the South Pacific Ocean, about Vanuatu three-quarters of the way from Hawaii to Australia. (NCI)

C17259 WLF WALLIS AND Islands in the South Pacific Ocean, about two-thirds of Wallis and Futuna FUTUNA the way from Hawaii to New Zealand. (NCI)

C17740 WSM SAMOA A group of islands in the South Pacific Ocean, about Samoa one-half of the way from Hawaii to New Zealand. (NCI)

C17264 YEM YEMEN A country in the Middle East, bordering the Arabian Yemen Sea, Gulf of Aden, and Red Sea, between Oman and Saudi Arabia. (NCI)

C17151 ZAF SOUTH AFRICA A country in Southern Africa, at the southern tip of the South Africa continent of Africa. (NCI)

C17267 ZMB ZAMBIA A country in Southern Africa, east of Angola. (NCI) Zambia

C17268 ZWE ZIMBABWE A country in Southern Africa, between South Africa Zimbabwe and Zambia. (NCI)

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 21 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C78731 - DATEST - Drug Accountability Test Name Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C78721 Dispensed Amount Dispensed The quantity of a product that has been dispensed. Dispensed Amount Amount (NCI)

C78722 Returned Amount Returned The quantity of a product that has been returned. (NCI) Returned Amount Amount

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 22 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C78732 - DATESTCD - Drug Accountability Test Code Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C78721 DISPAMT Dispensed The quantity of a product that has been dispensed. Dispensed Amount Amount (NCI)

C78722 RETAMT Returned The quantity of a product that has been returned. (NCI) Returned Amount Amount

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 23 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C66788 - DICTNAM - Dictionary Name Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C49471 COSTART Coding Symbols A terminology developed and used by the Food and Thesaurus of Adverse Reaction Term for a Thesaurus Drug Administration (FDA) for the coding, filing and Coding Symbols of Adverse retrieving of post marketing adverse reaction reports. Reaction Terms (NCI)

C49474 ICD International A system of categories to which morbid entries are International Classification of Classification of assigned according to established criteria. Included is Diseases Diseases the entire range of conditions in a manageable number of categories, grouped to facilitate mortality reporting. It is produced by the World Health Organization (from ICD-10, p1). The Clinical Modifications, produced by the United States Dept. of Health and Human Services, are larger extensions used for morbidity and general epidemiological purposes, primarily in the U.S. (MSH2005_2004_10_12)

C49476 LOINC Logical Published by The Regenstrief Institute, the Logical Logical Observation Identifiers Observation Observation Identifiers Names and Codes covers Names and Codes Identifiers clinical and clinical laboratory terminology. (NCI) Names and Codes

C43820 MedDRA Medical MedDRA is an international medical terminology MedDRA Dictionary for designed to support the classification, retrieval, Regulatory presentation, and communication of medical Activities information throughout the medical product regulatory cycle. MedDRA was developed under the auspices of the International Conference on Harmonisation of Technical Requirements for Registration of Pharmaceuticals for Human Use (ICH). The MedDRA Maintenance and Support Services Organization (MSSO) holds a contract with the International Federation of Pharmaceutical Manufacturers Associations (IFPMA) to maintain and support the implementation of the terminology. (NCI)

C53489 SNOMED Systematized A multiaxial, hierarchical classification system for Systematized Nomenclature of Nomenclature of diseases in man developed by the College of American Medicine Medicine Pathologists. (NCI)

C49468 WHOART World Health A terminology implemented by the World Health World Health Organization Adverse Organization Organization to describe adverse reactions to a Reaction Terminology Adverse prescribed medication or treatment regimen. (NCI) Reaction Terms

C49475 WHODD World Health A reference source of drugs and drug associated World Health Organization Drug Organization information maintained by the World Health Dictionary Drug Dictionary Organization. (NCI)

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 24 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C99074 - DIR - Directionality Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C25231 ANTERIOR Denoting the front portion of the body or a structure. Anterior

C25423 APICAL Relating to or located at the apex. Apical

C90067 BASAL Relating to or located at the lowest portion of a Basal structure.

C73851 CAUDAL Toward the tail in a body. Caudal

C25445 CENTRAL A point or area that is approximately central within Center some larger region or structure. (NCI)

C37936 CRANIAL Toward the head in a body. Cranial

C25240 DEEP Extending relatively far inward. (NCI) Deep

C25237 DISTAL Situated farthest from a point of reference. Distal

C45874 DORSAL Pertaining to the back or upper surface of the body. Dorsal

C90376 DORSOLATERAL Toward the back and side of a body. Dorsolateral

C90386 FORE Of or involving the front of a main body. (NCI) Fore

C90393 HIND Of or involving the back of a main body. (NCI) Hind

C25353 INFERIOR Pertaining to a point below a given reference point. Inferior

C37980 INNER Inside or closer to the inside of the body or object. Inner (NCI)

C73705 INTERMEDIATE Located between two points or extremes. Intermediate

C25309 LOWER The bottom one of two. (NCI) Lower

C25232 MEDIAL Toward the middle or in a limb toward the median Medial plane.

C38166 OUTER Being on or toward the outside of the body or object. Outer (NCI)

C25233 PERIPHERAL On or near an edge or constituting an outer boundary; Peripheral the outer area. (NCI)

C25622 POSTERIOR Denoting the back portion of the body or a structure. Posterior

C25236 PROXIMAL Situated nearest to a point of reference. Proximal

C94393 ROSTRAL Toward the muzzle in the head. Rostral

C25239 SUPERFICIAL Of or pertaining to the exterior surface. (NCI) Superficial

C25235 SUPERIOR Pertaining to a point above a given reference point. Superior

C25245 SURFACE The extended two-dimensional outer layer or area of a Surface three-dimensional object. (NCI)

C90069 TIP The pointed end of a structure. Tip

C25355 UPPER The top one of two. Upper

C45875 VENTRAL Pertaining to the front or lower surface of the body. Ventral

C98798 VENTROLATERAL Of or pertaining to the front and side of a main body. Ventrolateral (NCI)

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 25 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C66734 - DOMAIN - Domain Abbreviation Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C49563 AD Analysis Dataset Datasets used for statistical analysis and reporting by Analysis Dataset Domain the sponsor. These are submitted in addition to the data tabulation datasets.

C49562 AE Adverse Events Adverse events may be captured either as free text or a Adverse Event Domain pre-specified list of terms.

C49565 AU Autopsy Additional data about deaths, specific to findings from Autopsy Domain autopsies.

C95083 BG Body Weight Body weight gain is the actual difference between two Body Weight Gain Domain Gain body weight measurements for any given interval for a subject. This is most commonly shown as the difference between two consecutive body weight measurements.

C95084 BH Behavioral This domain captures behavioral testing measurements Behavioral Domain on individual subjects.

C49566 BM Bone Findings resulting from evaluations of bone mineral Bone Measurements Domain Measurements density.

C49567 BR Biopsy Findings resulting from biopsies. Biopsy Domain

C95085 BW Body Weight This domain captures body weights collected for Body Weight Domain subjects during the study and at the end of the study (terminal body weights).

C85441 CE Clinical Events A dataset used to capture clinical events of interest Clinical Events Domain that would not be classified as adverse events.

C95086 CL Clinical This domain captures clinical sign information Clinical Observation Domain Observation including ophthalmology, physical examination, and dermal examination collected in life while executing the study.

C49568 CM Concomitant Case report form (CRF) data that captures the Concomitant Medication Domain Meds Concomitant and Prior Medications/Therapies used by the subject. Examples are the Concomitant Medications/Therapies given on an as needed basis and the usual Background Medications/Therapies given for a condition.

C49569 CO Comments The Comments dataset accommodates two sources of Comment Domain comments: 1) those collected alongside other data on topical case report form (CRF) pages such as Adverse Events and 2) those collected on a separate page specifically dedicated to comments.

C49578 DA Drug Data regarding the accountability of study drug, such as Drug Accountability Domain Accountability information on the receipt, dispensing, return, and packaging.

C49570 DC Disease Data related to the characteristics of a specific disease Disease Characteristics Domain Characteristics state under study for a subject.

C95087 DD Death Diagnosis This domain captures the diagnosis of the cause of Death Diagnosis Domain death for a subject.

C49572 DM Demographics The Demographics domain includes a set of essential Demographics Domain standard variables that describe each subject in a clinical study. It is the parent domain for all other observations for human clinical subjects

C95088 DP Developmental This domain captures the outcome of developmental Developmental Milestone Domain Milestone milestone testing during a scheduled period of observation.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 26 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C66734 - DOMAIN - Domain Abbreviation Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C49576 DS Disposition A subject domain utilized for the submission of Disposition Domain information encompassing and representing data, vocabulary or records related to disposition. (NCI)

C49585 DV Protocol The intent of the domain is to capture protocol Protocol Deviations Domain Deviations violations and deviations during the course of the study and will store only those criteria violation by or deviated from by the subject and not a response to each violation or deviation.

C49625 EE Electroencephal Findings resulting from electroencephalogram (EEG) Electroencephalogram Domain ogram tests.

C49626 EG Electrocardiogra Findings related to the collection of ECG data, Electrocardiogram Domain m including position of the subject, method of evaluation, all cycle measurements and all findings from the ECG including an overall interpretation if collected or derived.

C49587 EX Exposure The Exposure domain model records the details of a Exposure Domain subject's exposure to protocol-specified study treatment. Study treatment may be any intervention that is prospectively defined as a test material within a study, and is typically but not always supplied to the subject.

C85442 FA Findings About A dataset used to capture the findings about an event or Findings About Events or Events or intervention that cannot be represented within an event Interventions Domain Interventions or intervention record or as a supplemental qualifier.

C95089 FE Fertility This domain captures test results relative to male and Fertility Domain female fertility.

C49588 FH Family History A subject domain utilized for the submission of Family History Domain information encompassing and representing data, vocabulary or records related to family history. (NCI)

C95090 FW Food And Water This domain captures food/water consumption of Food and Water Consumption animals in the study. The data in this domain is derived Domain data.

C95091 FX Fetal and This domain captures observations for fetal and pup Fetal and Neonatal Developmental Neonatal morphological examinations. Morphology Domain Developmental Morphology

C49589 HU Healthcare Healthcare resource utilization data such as subject Healthcare Resource Utilization Resource visits to physicians, hospitalizations, and nursing home Domain Utilization stays.

C95092 IC Implantation The Implantation Classification domain provides a Implantation Classification Domain Classification record for each implantation identified for the scheduled cesarean section component of a study.

C61536 IE Inclusion/ The intent of the domain model is to only collect those Inclusion Exclusion Domain Exclusion criteria that cause the subject to be in violation of the inclusion/exclusion criteria not a response to each criterion.

C49592 LB Laboratory Data Laboratory test findings including, but is not limited to Laboratory Data Domain hematology, clinical chemistry and urinalysis data. This domain does not include microbiology or pharmacokinetic data, which are stored in separate domains.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 27 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C66734 - DOMAIN - Domain Abbreviation Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C95093 LR Cesarean Section This domain captures litter based results in female Cesarean Section and Delivery Litter and Delivery animals for cesarean section and/or delivery Results Domain Litter Results components of a study, including litter survival during preweaning.

C95094 MA Macroscopic The gross pathology findings recorded at necropsy. Macroscopic Findings Domain Findings

C49602 MB Microbiology Microbiology specimen findings, including gram stain Microbiology Specimen Domain results, and organisms found.

C49603 MH Medical History The medical history dataset includes the subject's prior Medical History Domain history at the start of the trial. Examples of subject medical history information could include general medical history, gynecological history, and primary diagnosis.

C95095 MI Microscopic The histopathology findings and microscopic Microscopic Findings Domain Findings evaluations recorded.

C49604 ML Meal Data Information regarding the subject's meal consumption, Meal Data Domain such as fluid intake, amounts, form (solid or liquid state), frequency, etc., typically used for pharmacokinetic analysis.

C61531 MS Microbiology This includes microbiology susceptibility test results, Microbiology Susceptibility Domain Susceptibility plus results of any other organism-related tests.

C49605 OM Organ Findings from organ measurement evaluations. Organ Measurement Domain Measurements

C49606 PC Pharmacokinetic Concentrations of drugs/metabolites in fluids or Pharmacokinetic Concentration Concentration tissues as a function of time. Domain

C49608 PE Physical Exam Findings collected during a physical examination of Physical Exam Domain the subject. It has findings that are discovered that are related to body systems. Does not include vital signs measurements, which are stored in the vital signs domain.

C61529 PG Pharmacogenomi Pharmacogenomics findings that initially focus on Pharmacogenomics Domain cs genotype and gene expression data.

C95097 PM Palpable Masses This domain captures information of any palpable Palpable Masses Domain masses examined during the experimental phase.

C49607 PP Pharmacokinetic Pharmacokinetic parameters derived from Pharmacokinetic Parameters Domain Parameters pharmacokinetic concentration-time (PC) data.

C49609 QS Questionnaires Questionnaire data may include, but are not limited to Questionnaire Domain the following: subject reported outcomes, validated or non-validated questionnaires, and validated or non-validated diaries (i.e. data with a common topicality).

C49610 SC Subject The subject characteristics domain is for data not Subject Characteristics Domain Characteristics collected in other domains that is subject-related.

C49616 SE Subject Element The subject element table describes the actual order of Subject Element Domain elements followed by the subject, together with the start date/time and end date/time for each element.

C49611 SG Surgery Surgical information. Surgery Domain

C95099 SJ Subject Stages The Subject Stages domain captures subject level Subject Stages Domain non-treatment related blocks of time known as stages, such as Gestation, Lactation and Premating.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 28 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C66734 - DOMAIN - Domain Abbreviation Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C49612 SK Skin Test Findings from diagnostic skin tests. Skin Test Domain

C49613 SL Sleep Findings from diagnostic sleep tests Sleep Polysomnography Domain Polysomnograph (polysomnography). y Data

C49614 ST Stress (Exercise) Findings from exercise stress tests. Stress Exercise Test Data Domain Test Data

C49615 SU Substance Use The intent of the domain is to capture substance use Substance Use Domain information that may be used to assess the efficacy and/or safety of therapies that look to mitigate the effects of chronic substance use.

C49617 SV Subject Visits The subject visits table describes the actual start and Subject Visits Domain end data/time for each visit of each individual subject.

C49618 TA Trial Arms The trial arms table describes each planned arm in the Trial Arms Domain trial. An arm is described as an ordered sequence of elements.

C49619 TE Trial Elements The trial elements table describes the element code Trial Elements Domain that is unique for each element, the element description, and the rules for starting and ending an element.

C95100 TF Tumor Findings This domain captures the tumor findings of the Tumor Findings Domain nonclinical subject.

C49620 TI Trial The trial summary information domain is not subject Trial Inclusion and Exclusion Inclusion/ oriented. It contains one record for each of the Criteria Domain Exclusion inclusion and exclusion criteria for the trial. Criteria

C95101 TP Trial Paths The trial paths domain is not subject oriented. This Trial Paths Domain domain provides the complete planned non-treatment related sequences of stages for each path in a study.

C53483 TS Trial Summary The trial summary information domain is not subject Trial Summary Domain oriented. It contains one record for each trial summary characteristic.

C95102 TT Trial Stages The trial stages domain is not subject oriented. It Trial Stages Domain captures non-treatment related planned blocks of time known as stages, such as Gestation, Lactation and Premating.

C49621 TV Trial Visits The trial visits table describes the planned order and Trial Visits Domain number of visits in the study within each arm.

C95103 TX Trial Sets The trial stages domain is not subject oriented. It Trial Sets Domain contains one record for each trial set characteristic including experimental factors, treatment factors, inherent characteristics, or distinct sponsor designations.

C49622 VS Vital Signs Measurements including but not limited to blood Vital Signs Domain pressure, temperature, respiration, body surface area, BMI, height and weight.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 29 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C74558 - DSCAT - Category for Disposition Event Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C74590 DISPOSITION EVENT Disposition The group of incidents that occur during a clinical trial Protocol Disposition Event Event and describe whether a subject completed the study epoch or the reason this event did not occur. The subject's disposition is often described for each phase of the study.

C74589 OTHER EVENT Other Event Other important events that occur during a trial but are Protocol Event not driven by protocol requirements.

C74588 PROTOCOL MILESTONE Protocol Occurrences within some epochs that are initiated by a Protocol Milestone Milestone protocol-specified event. The most common protocol milestone is "Informed Consent Obtained" which usually documents the start of the study.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 30 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C90013 - EGLEAD - ECG Lead Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C90404 LEAD CM5 A bipolar EKG lead with the right thoracic limb Lead Site CM5 electrode placed on the manubrium and left thoracic limb electrode placed at the surface marking of the V5 position (just above the 5th interspace in the anterior axillary line). The left pelvic limb lead acts as a neutral and may be placed anywhere. The C refers to 'clavicle' where it is often placed. (NCI)

C90405 LEAD CV5RL A unipolar chest lead used mostly in large animals. Lead Site CV5RL Placed on the sixth ICS on the right side of the thorax along a line parallel to the level of the point of the humeralradial joint.

C90406 LEAD CV6LL V1 electrode (+) placed in the 6th intercostal space on Lead Site CV6LL the left side of the thorax along a line parallel to the level of the point of the humeralradial joint.

C90407 LEAD CV6LU V2 electrode (+) placed in the 6th intercostal space on Lead Site CV6LU the left side of the thorax along a line parallel to the level of the point of the shoulder. (NCI)

C90408 LEAD I A bipolar electrocardiogram limb lead which records Lead Site I the voltage between the negative electrode on the right thoracic limb and the positive electrode on the left thoracic limb. (NCI)

C90409 LEAD II A bipolar electrocardiogram limb lead which records Lead Site II the voltage between the negative electrode on the right thoracic limb and the positive electrode on the left pelvic limb. (NCI)

C90410 LEAD III A bipolar electrocardiogram limb lead which records Lead Site III the voltage between the negative electrode on the left thoracic limb and the positive electrode on the left pelvic limb. (NCI)

C90412 LEAD V1 A unipolar electrocardiogram lead site; the electrode Lead Site V1 is placed at the fourth intercostal space on the anterior chest wall (between ribs 4 and 5) to the right of the sternal border. In small animals, it is placed at the right fifth intercostal space near the sternum. (NCI)

C90413 LEAD V10 A unipolar chest lead at which the electrode is placed Lead Site V10 over the dorsal spinous process of 7th thoracic vertebra. (NCI)

C90414 LEAD V2 A unipolar electrocardiogram lead site; the electrode Lead Site V2 is placed on the anterior chest wall at the fourth intercostal space (between ribs 4 and 5) to the left of the sternal border. In small animals it corresponds to V2-V3 where it is placed at the 6th left intercostal space near the sternum. In large animals it is placed over the 6th rib at the level of the costochondral junction on the left side of the thorax.

C90415 LEAD V3 A unipolar electrocardiogram lead site; the electrode Lead Site V3 is placed on the anterior chest wall midway between leads V2 and V4. In large and small animals, it is placed over the dorsal spinous process of the 7th thoracic vertebra. (NCI)

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 31 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C90013 - EGLEAD - ECG Lead Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C90416 LEAD V4 A unipolar electrocardiogram lead site; the electrode Lead Site V4 is placed at the fifth intercostal space on the anterior chest wall (between ribs 5 and 6) at the left midclavicular line. In small animals it corresponds to V4-V6 where it is placed at the 6th left intercostal space near the costochondral junction. In large animals it is placed over the 6th rib at the level of a horizontal line drawn through the scapulohumeral articulation on the left side of the thorax. (NCI)

C90417 LEAD V5 A unipolar electrocardiogram lead site; the electrode Lead Site V5 is placed on the anterior chest wall level with lead V4 at the left anterior axillary line. In large animals it is placed on the sixth ICS on the right side of the thorax along a line parallel to the level of the point of the shoulder corresponding to the electrical center of the heart (central terminal). (NCI)

C90418 LEAD V6 A unipolar electrocardiogram lead site at which the Lead Site V6 electrode is placed on the anterior chest wall level with lead V5 at the left midaxillary line .

C90403 LEAD aV6 An augmented unipolar lead placed at the sixth Lead Site aV6 intercostal space on the midaxillary line. (NCI)

C90360 LEAD aVF An augmented unipolar electrocardiogram limb lead in Augmented Vector Foot which the positive (red) electrode is situated on the left pelvic limb and the negative electrode is a combination of the right thoracic limb (white) electrode and the left thoracic limb (black) electrode. Measures the electrical activity of the electrode on the left pelvic limb.

C90361 LEAD aVL An augmented unipolar electrocardiogram limb lead in Augmented Vector Left which the positive (black) electrode is situated on the left thoracic limb and the negative electrode is a combination of the right thoracic limb (white) electrode and the left pelvic limb (red) electrode. Measures the electrical activity of the electrode on the left thoracic limb. (NCI)

C90362 LEAD aVR An augmented unipolar electrocardiogram limb lead in Augmented Vector Right which the positive (white) electrode is situated on the right thoracic limb and the negative electrode is a combination of the left thoracic limb (black) electrode and the left pelvic limb (red) electrode. Measures the electrical activity of the electrode on the right thoracic limb. (NCI)

C90411 LEAD rV2 A unipolar precordial lead placed at the second Lead Site rV2 intercostal space to the left of the sternum. (NCI)

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 32 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C71151 - EGMETHOD - ECG Test Method Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C90349 10 LEAD STANDARD 10 Lead Standard An electrocardiogram lead placement on the subject 10 Lead Standard using a ten electrode lead set to synthesize standard 12 lead electrocardiograph data to elicit an electrical view of the heart.

C71125 12 LEAD 1 LEAD MISSING 12 Lead 1 Lead An electrocardiogram (ECG) lead placement whereby 12 Lead Placement 1 Lead Missing Missing 12 leadpoints are recorded but one standard lead position is missing therefore requiring a Mortara source consistency filter. (NCI)

C71116 12 LEAD CABRERA 12 Lead Cabrera An electrocardiogram (ECG) lead placement whereby 12 Lead Placement Cabrera the display of the 12 standard ECG leads is in an orderly sequence in a single horizontal display of: aVL, I, -aVR, II, aVF, III, V1 to V6. In the Cabrera display the limb lead aVR is inverted (-aVR) to obtain the same positive leftward orientation as the other 5 limbs. (NCI)

C71123 12 LEAD EASI DOWER 12 Lead EASI An electrocardiogram (ECG) lead placement whereby Lead Placement EASI Dower TRANSFORMATION Dower 4 chest electrodes and 1 reference electrode are used Transformation Transformation to allow for continuous monitoring at the clinical level. This placement creates a 12 lead ECG that allows the acquisition of simultaneous events in the frontal, horizontal and sagittal heart planes with the linear transformation of vectors. This system provides a three-dimensional portrayal of the heart and uses mathematical and fixed coefficients for each lead. (NCI)

C71103 12 LEAD MASON LIKAR 12 Lead Mason An electrocardiogram (ECG) lead placement whereby 12 Lead Placement Mason Likar Likar 12 leadpoints are recorded but the standard lead positions have been modified for ECG recording during exercise. Exercise stress testing requires moving the limb electrodes to more central positions on the thorax. The electrodes are placed in bony prominences close to the bases of the respective limbs in order to avoid skeletal muscle artifact, provide stability for recording electrodes and to record waveforms similar to the standard limb sites. (NCI)

C71110 12 LEAD MODIFIED 12 Lead An electrocardiogram (ECG) lead placement whereby 12 Lead Placement Mason Likar MASON LIKAR Modified Mason 12 leadpoints are recorded but the Mason Likar lead Modified Likar positions have been modified so that V1 to V6 on the chest are part of a single electrode pad. In addition, lead CM5 is substituted for lead aVR. (NCI)

C71114 12 LEAD NON-STANDARD 12 Lead An electrocardiogram (ECG) lead placement whereby 12 Lead Placement Non-Standard Non-Standard the limb leads are placed on the torso for easier and faster application in emergency situations. (NCI)

C71112 12 LEAD SINGLE PAD 12 Lead Single An electrocardiogram (ECG) lead placement whereby 12 Lead Placement Chest Pad 12 leadpoints are recorded but the standard lead positions have been modified so that all leads on the chest are part of a single electrode pad. (NCI)

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 33 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C71151 - EGMETHOD - ECG Test Method Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C71102 12 LEAD STANDARD 12 Lead Standard An electrocardiogram (ECG) lead placement whereby 12 Lead Placement Standard 12 leads are recorded, with each lead representing an electrical view of the heart. The six leads recorded in the frontal plane are derived from the placement of 3 electrodes (RA or Right Arm, LA, or Left Arm, and LL or Left Leg). These bipolar frontal leads form the basis of Einthoven's triangle, and are represented by leads I, II, and III. Three other derived (or augmented) bipolar frontal vectors are also recorded on a standard 12-lead EKG, aVR, aVF, and aVL. 6 unipolar leads, corresponding to V1 - V6 measure the electrical activity in the horizontal plane. The placement for the V leads is as follows: V1: right 4th intercostal space,V2: left 4th intercostal space, V3: halfway between V2 and V4, V4: left 5th intercostal space, mid-clavicular line, V5: horizontal to V4, anterior axillary line, V6: horizontal to V5, mid-axillary line. (NCI)

C71101 12 LEAD UNSPECIFIED 12 Lead An electrocardiogram (ECG) lead placement whereby 12 Lead Placement Unspecified Unspecified 12 leadpoints are recorded but the position of the leads is unspecified. (NCI)

C90350 6 LEAD STANDARD 6 Lead Standard An electrocardiogram lead placement on the subject 6 Lead Standard using a six electrode lead set with three standard leads and three augmented derived leads to elicit an electrical view of the heart.

C71121 BIPOLAR UNCORRECTED Bipolar An electrocardiogram (ECG) lead placement whereby Lead Placement Bipolar Uncorrected XYZ LEAD SYSTEM uncorrected XYZ the X+ lead is placed at the right mid-axillary line ate XYZ lead system the 4th intercostal space, X- at the left mid-axillary line at he 4th intercostal space, Y+ at the proximal left leg, Y- at the superior aspect of the manubrium, Z+ at the direct posterior to Z- and Z- at the 4th intercostal space at the left sternal margin. (NCI)

C71120 CUBE LEAD SYSTEM Cube lead system An electrocardiogram (ECG) lead placement that is a Lead Placement Cube type of uncorrected vectorcardiograph. This lead system is based on a rectangular body axis. It uses an extra number of electrodes to make it three-dimensional. (NCI)

C71118 FRANK LEAD SYSTEM Frank lead An electrocardiogram (ECG) lead placement for Lead Placement Frank system determining 3 orthogonal components X (right to left direction), Y (foot to head direction) and Z (back to front direction) of the heart. For this method a minimum of 4 electrodes are needed that represent the right arm, left arm, left leg and back. However, usually 7 electrodes are used to avoid dependence on the dipole location and facilitate interpretation. (NCI)

C71119 MCFEE-PARUNGAO LEAD McFee-Parungao An electrocardiogram (ECG) lead placement for Lead Placement McFee-Parungao SYSTEM lead system determining 3 orthogonal components X (back to front), Y (right to left) and Z (foot to head) of the heart. This system places the electrodes closer to the heart to achieve better orthogonality and a homogeneous lead field. (NCI)

C71122 PSEUDO-ORTHOGONAL Pseudo-orthogon An electrocardiogram (ECG) lead placement that Lead Placement Pseudo Orthogonal XYZ LEAD SYSTEM al XYZ lead allows monitoring and recording of cardiac electrical XYZ system activity. A V1-type lead is used whose positive electrode is localized in the 4th intercostal space, 2.5cm from the sternum. Its negative electrode is placed below the left clavicle. An addition of lead V5 and aVF can be made to facilitate interpretation. (NCI)

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 34 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C71151 - EGMETHOD - ECG Test Method Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C71128 STANDARD 12-LEAD AND Standard 12-lead An electrocardiogram (ECG) lead placement whereby 12 Lead Placement Standard And CC5-CM5-ML and 12 leadpoints are recorded but the standard lead CC5-CM5-ML CC5-CM5-ML positions have been modified so that the negative reference is at CM5 and the active electrode is at the left leg position. (NCI)

C71126 STANDARD 12-LEAD AND Standard 12-lead An electrocardiogram (ECG) lead placement whereby 12 Lead Placement Standard And CM5-CC5-CH5 and 12 leadpoints are recorded but the standard lead CC5-CM5-CH5 CM5-CC5-CH5 positions have been modified so that the bipolar lead groups place the negative of the reference electrode over the manubrium (CM5), the right scapula (CB5), V5R (CC5) or on the forehead (CH5) and the active electrode at V5. (NCI)

C71131 STANDARD 12-LEAD Standard 12-lead An electrocardiogram (ECG) lead placement whereby 12 Lead Placement Standard EXTENDED LEFT extended to the the standard lead placement is modified by having Extended Left left by V7, V8, leads V7, V8 and V9. (NCI) V9

C71130 STANDARD 12-LEAD Standard 12-lead An electrocardiogram (ECG) lead placement whereby 12 Lead Placement Standard EXTENDED RIGHT extended to the the rightward oriented V leads progress from V1R, Extended Right right by V5R, placed instead of the standard V2, to V6R. The V3 lead V4R, V3R in the standard placement is replaced by V4R. (NCI)

C71115 STANDARD LEADS FOR Standard leads Limb leads on the back (shoulder and on the hips). Lead Placement Bicycle BICYCLE EXERCISE for bicycle (NCI) exercise. Limb leads on the back (shoulder and on the hips)

C71117 STANDARD LEADS ONE Standard leads An electrocardiographic lead placement schema in Lead Placement Standard Intercostal INTERCOSTAL SPACE one intercostal which the V leads are placed one intercostal space Space Higher HIGHER space higher cephalad to the position they would have in the standard lead placement schema. (NCI)

C71092 VECTORCARDIOGRAPH Vectorcardiograp A recording of the electrical activity of the heart Vectorcardiograph Corrected CORRECTED h Corrected displayed in the form of a vector loop, corrected for anatomic inconsistencies. (NCI)

C71093 VECTORCARDIOGRAPH Vectorcardiograp A recording of the electrical activity of the heart Vectorcardiograph Uncorrected UNCORRECTED h Uncorrected displayed in the form of a vector loop, uncorrected for anatomic inconsistencies. (NCI)

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 35 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C71150 - EGSTRESC - ECG Result Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C62015 1ST DEGREE AV BLOCK 1st degree AV A delay in the time required for the conduction of an AV Block First Degree block electrical impulse through the atrioventricular (AV) node beyond 0.2 seconds; prolongation of the PR interval beyond 200 milliseconds. (NCI)

C71044 2:1 AV BLOCK 2:1 AV block A electrocardiographic finding of an electrical 2:1 Atrioventricular Block phenomenon in which the ratio of electrical impulse generated above the atrioventricular node to the number of impulses conducted through to the ventricles is 2:1. (NCI)

C62016 2ND DEGREE AV BLOCK 2nd degree AV Intermittent failure of atrial electrical impulse AV Block Second Degree block conduction through the atrioventricular (AV) node to the ventricles. (NCI)

C50501 3RD DEGREE AV BLOCK 3rd degree AV Complete failure of atrial electrical impulse AV Block Third Degree block conduction through the AV node to the ventricles. (NCI)

C62266 ACCELERATED Accelerated The term accelerated idioventricular rhythm describes Accelerated Idioventricular Rhythm IDIOVENTRICULAR idioventricular an ectopic ventricular rhythm with 3 or more RHYTHM rhythm consecutive ventricular premature beats with a rate faster than the normal ventricular intrinsic escape rate of 30 to 40 beats per minute, but slower than ventricular tachycardia. Accelerated idioventricular rhythm differs from ventricular tachycardia by additional features such as the onset with a long coupling interval and the end by a gradual decrease of the ventricular rate or increase of the sinus rate. (NCI)

C71065 ACUTE ANTERIOR WALL Acute Anterior Electrocardiographic finding showing a current of Acute Anterior Wall Myocardial MI Wall Myocardial injury in leads corresponding to the anatomic region of Infarction Infarction the anterior wall of the heart. (NCI)

C71066 ACUTE INFERIOR WALL MI Acute Inferior Electrocardiographic finding showing a current of Acute Inferior Wall Myocardial Wall Myocardial injury in leads corresponding to the anatomic region of Infarction Infarction the inferior wall of the heart. (NCI)

C71067 ACUTE LATERAL WALL MI Acute Lateral Electrocardiographic finding showing a current of Acute Lateral Wall Myocardial Wall Myocardial injury in leads corresponding to the anatomic region of Infarction Infarction the lateral wall of the heart. (NCI)

C71068 ACUTE POSTERIOR WALL Acute Posterior Electrocardiographic finding showing a current of Acute Posterior Wall Myocardial MI Wall Myocardial injury in leads corresponding to the anatomic region of Infarction Infarction the posterior wall of the heart. (NCI)

C71057 ADENOSINE-SENSITIVE Adenosine-sensit A condition that occurs as a result of cAMP-mediated Adenosine-Sensitive Ventricular VENTRICULAR ive ventricular triggered activity and typically originates from the Tachycardia TACHYCARDIA tachycardia right ventricular outflow tract (RVOT). This type of tachycardia occurs in patients with apparently normal hearts. (NCI)

C71069 ANTERIOR WALL Anterior Wall Electrocardiographic finding showing an injury in Anterior Wall Myocardial Infarction MYOCARDIAL Myocardial leads corresponding to the anatomic region of the INFARCTION Infarction anterior wall of the heart. (NCI)

C71039 ATRIAL ENLARGEMENT Atrial An electrocardiographic finding which comprises left, EKG Finding Atrial Enlargement Enlargement right or bilateral atrial enlargement. (NCI)

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 36 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C71150 - EGSTRESC - ECG Result Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C50466 ATRIAL FIBRILLATION Atrial fibrillation A supraventricular arrhythmia characterized by Atrial Fibrillation uncoordinated atrial myocardium activation due to multiple reentry circuits with consequent deterioration of atrial mechanical function. Instead of intermittently contracting, the atria quiver continuously in a chaotic pattern, causing a totally irregular, often tachycardia ventricular rate. On the ECG it is described by the replacement of consistent P waves by rapid oscillations or fibrillatory waves that vary in size, shape, and timing, associated with an irregular, frequently rapid ventricular response when atrioventricular conduction is intact. (NCI)

C51224 ATRIAL FLUTTER Atrial flutter An electrocardiographic finding of an organized Atrial Flutter rhythmic contraction of the atria which is generally at a rate of 200-300 beats per minute. (NCI)

C35481 ATRIAL TACHYCARDIA Atrial Any rapid heart rhythm originating in the atria. Atrial Atrial Tachycardia tachycardia fibrillation and atrial flutter are varieties of atrial tachycardia. Atrial tachycardia is an electrical circuit originating in the upper or atrial chambers. This electrical circuit or focus takes over and generates rapid impulses across the atrial chambers. These impulses are transmitted to the ventricular chambers resulting in a rapid rate. These arrhythmias may originate from a variety of places across the atria. They may exist as an isolated problem or be related to an ongoing structural problem within the heart. (NCI)

C71045 ATRIOVENTRICULAR Atrioventricular An electrocardiographic finding in which the electrical Atrioventricular Dissociation DISSOCIATION dissociation activity of the atria and ventricles are causally independent of one another. (NCI)

C83811 AV MOBITZ I AV Mobitz I Intermittent failure of atrial electrical impulse AV Mobitz I conduction through the atrioventricular (AV) node to the ventricles, characterized by a progressively lengthening PR interval prior to the block of an atrial impulse.

C83812 AV MOBITZ II AV Mobitz II Intermittent failure of atrial electrical impulse AV Mobitz II conduction through the atrioventricular (AV) node to the ventricles, characterized by a relatively constant PR interval prior to the block of an atrial impulse.

C35058 AV NODE RE-ENTRY AV node re-entry A supraventricular tachycardia due to reentry along a Atrioventricular Nodal Reentry circuit contained within the AV node. AVNRT is the Tachycardia most common form of supraventricular tachycardia and usually presents as a narrow QRS complex tachycardia at a rate between 150 and 250 beats per minute. (NCI)

C62261 AV RE-ENTRANT AV re-entrant A supraventricular tachycardia due to reentry along a Atrioventricular Reentrant TACHYCARDIA tachycardia circuit including a concealed AV nodal bypass tract. Tachycardia This tachycardia circuit proceeds in an antegrade fashion through the AV node and then is conducted retrograde through the bypass tract into the atria. (NCI)

C71046 BIFASCICULAR BLOCK Bifascicular An electrocardiographic finding comprising right Bifascicular Block block bundle branch block and left anterior fascicular block, or right bundle branch block and left posterior fascicular block. Defects occurring in two of the three divisions of the conduction system of the heart are considered bifascicular blocks. Technically left bundle branch block may be considered a bifascicular block. (NCI)

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 37 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C71150 - EGSTRESC - ECG Result Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C71054 BIGEMINY Bigeminy An electrocardiographic finding of a normal QRS Bigeminy followed by a premature ventricular contraction; a rhythmic pairing of normal and abnormal beats originating in the ventricles in a 1-1 ratio. (NCI)

C92228 BORDERLINE QTcB Borderline QTcB An electrocardiographic finding in which the QTcB is Borderline QTcB approximately 430-470 msec. There is variation among subpopulations.

C92229 BORDERLINE QTcF Borderline QTcF An electrocardiographic finding in which the QTcF is Borderline QTcF approximately 430-470 msec. There is variation among subpopulations.

C37920 BRADYCARDIA Bradycardia Non-sinus origin slow heart rate. Bradycardia

C71062 BUNDLE BRANCH Bundle branch An uncommon form of ventricular tachycardia (VT) Bundle Branch Re-Entrant REENTRANT reentrant incorporating both bundle branches into the reentry Ventricular Tachycardia TACHYCARDIA tachycardia circuit. Surface electrocardiogram (ECG) of sinus rhythm (SR) characteristically shows intraventricular conduction defects. Patients typically present with presyncope, syncope or sudden death because of VT with fast rates frequently above 200 beats per minute. The QRS morphology during VT is a typical bundle branch block pattern, usually left bundle branch block, and may be identical to that in SR. (NCI)

C62258 DELTA WAVE Delta wave An initial slurring (delta wave) of the QRS complex EKG Delta Wave due to the presence of an accessory pathway. This characteristic EKG pattern is typically seen in Wolff-Parkinson-White syndrome. (NCI)

C92230 EARLY R WAVE Early R Wave An electrocardiographic finding in which the amplitude Early R Wave Progression PROGRESSION Progression of the R wave is abnormally increased in the anterior precordial leads.

C62245 ECTOPIC ATRIAL RHYTHM Ectopic atrial A cardiac rhythm resulting from either an abnormal Ectopic Atrial Rhythm rhythm electrical focus in the atria or intra-atrial reentry. Atrial ectopic beats (AEB) refer to a contraction of the upper heart chamber which occurs before it would be expected. Atrial ectopic beats are also known as premature atrial beats, premature atrial complex (PAC), or atrial extrasystole. (NCI)

C71043 ECTOPIC Ectopic An electrocardiographic finding of a rhythm Ectopic Supraventricular Rhythm SUPRAVENTRICULAR supraventricular originating at a site other than the sinoatrial node, RHYTHM rhythm which is also above the atrioventricular node. (NCI)

C71042 ECTOPIC VENTRICULAR Ectopic A cardiac rhythm resulting from either an abnormal Ectopic Ventricular Rhythm RHYTHM ventricular electrical focus in the ventricle. Ventricular ectopic rhythm beats (VEB) refer to a contraction of the lower heart chamber which occurs before it would be expected. Ventricular ectopic beats are also known as premature ventricular beats, premature ventricular complex (PVC), or ventricular extrasystole. (NCI)

C71035 ELECTRICAL ALTERNANS Electrical An electrocardiographic finding in which there is an Electrical Alternans alternans alternating pattern of any of the waveform components. (NCI)

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 38 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C71150 - EGSTRESC - ECG Result Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C71061 FASCICULAR Fascicular A distinct subgroup of idiopathic ventricular Fascicular Tachycardia TACHYCARDIA tachycardia tachycardia (VT) that may be confused with either typical VT or supraventricular tachycardia (SVT). It is characterized by the absence of structural heart disease and classic electrocardiographic and electrophysiological features. It originates from the region of the posterior fascicle (or occasionally the anterior fascicle) of the left bundle branch and is partly propagated by the His-Purkinje network. It therefore produces QRS complexes of relatively short duration (0.11-0.14)s. (NCI)

C71063 IDIOPATHIC RIGHT Idiopathic right Idiopathic ventricular tachycardia (VT) is a type of Idiopathic Right Bundle Branch BUNDLE BRANCH BLOCK bundle branch ventricular tachycardia occurring unrelated to any Block VENTRICULAR block ventricular organic cardiac disease. The abnormality is probably TACHYCARDIA tachycardia congenital, be it a focus of abnormal automaticity or myocardial tissue that can sustain re-entry. The clinical presentation for idiopathic VT can be very much like a paroxysmal supraventricular tachycardia. That is, most patients are generally younger without overt cardiac disease and present with paroxysmal palpitations. Idiopathic ventricular tachycardia is not generally life-threatening. (NCI)

C62253 INAPPROPRIATE SINUS Inappropriate Inappropriate sinus tachycardia (IST) is a rare form of Inappropriate Sinus Tachycardia TACHYCARDIA sinus tachycardia supraventricular tachycardia involving the sinus node, in which a patient has an abnormally high heart rate, occurring both at rest and in response to stressors (such as physical activity). (NCI)

C71049 INCOMPLETE BUNDLE Incomplete An electrocardiographic finding of bundle branch Incomplete Bundle Branch Block BRANCH BLOCK bundle branch block which does not meet the criteria for a more block specific bundle branch block. (NCI)

C71047 INCOMPLETE LEFT Incomplete left An partial impairment of transmission of the cardiac Incomplete Left Bundle Branch BUNDLE BRANCH BLOCK bundle branch electrical impulse along the fibers of the left bundle Block block branch. (NCI)

C71048 INCOMPLETE RIGHT Incomplete right Various mechanisms may result in a pattern showing an Incomplete Right Bundle Branch BUNDLE BRANCH BLOCK bundle branch incomplete right bundle branch block (RBBB). These Block block include different degrees of conduction delay through the main trunk of the right bundle branch; increased conduction time through an elongated right bundle branch; diffuse Purkinje-myocardial delay due to right ventricular stretch or dilatation; surgical trauma or disease-related interruption of the major ramifications of the right branch (distal RBBB or right fascicular blocks); congenital variations of the distribution of the major ramifications resulting in a slight delay in the activation of the crista supraventricularis. (NCI)

C71070 INFERIOR WALL Inferior Wall Electrocardiographic finding showing an injury in Inferior Wall Myocardial Infarction MYOCARDIAL Myocardial leads corresponding to the anatomic region of the INFARCTION Infarction inferior wall of the heart. (NCI)

C71073 INTRAATRIAL Intraatrial A delay in impulse propagation through the atria. (NCI) Intra-Atrial Conduction Delay CONDUCTION DELAY Conduction Delay

C62271 INTRAVENTRICULAR Intraventricular A delay in transmission of cardiac electrical impulses Nonspecific Intraventricular CONDUCTION DELAY, conduction in the His-Purkinje system, diagnosed when the QRS is Conduction Delay NONSPECIFIC delay, modestly prolonged (< 120 msec) and the QRS pattern nonspecific and axis are not typical of a hemiblock. The conduction delay is considered to occur beyond the Purkinje's myocardial gates and arises from slow cell-to-cell conduction. The phenomenon is common in patients with acute MI. (NCI)

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 39 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C71150 - EGSTRESC - ECG Result Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C62248 ISORHYTHMIC Isorhythmic A type of atrioventricular dissociation characterized by Isorhythmic Atrioventricular DISSOCIATION dissociation atria and ventricles beating at similar rates, although Dissociation independently. (NCI)

C71030 J POINT ELEVATION J point elevation Elevation of the J point above the baseline; the J point J Point Elevation represents the end of ventricular depolarization and located at the terminus of the QRS complex. (NCI)

C71074 JUNCTIONAL Junctional An electrocardiographic finding in which the pacer of Junctional Bradycardia BRADYCARDIA bradycardia the heart is located in the AV junction, normally presenting with a narrow QRS complex at a rate less than 60 beats per minute. (NCI)

C71051 JUNCTIONAL RHYTHM Junctional An electrocardiographic finding in which the pacer of Junctional Rhythm rhythm the heart is located in the AV junction, normally presenting with a narrow QRS complex and a rate of 60-100 beats per minute. (NCI)

C35059 JUNCTIONAL Junctional An automatic tachycardia originating in the Junctional Tachycardia TACHYCARDIA tachycardia atrioventricular junction, typically arising in the conduction tissues surrounding the atrioventricular node. A junctional tachycardia tends to be a regular, narrow complex tachycardia and usually occurs during myocardial infarction, after heart surgery, or in digitalis intoxication. The rate may range from 140 to 250 beats per minute. (NCI)

C71075 LATERAL WALL Lateral Wall Electrocardiographic finding showing an injury in Lateral Wall Myocardial Infarction MYOCARDIAL Myocardial leads corresponding to the anatomic region of the INFARCTION Infarction lateral wall of the heart. (NCI)

C62267 LEFT ANTERIOR Left anterior An impairment of transmission of the cardiac Left Anterior Fascicular Block FASCICULAR BLOCK fascicular block electrical impulse along the fibers of the left anterior fascicle. In left anterior fascicular block (LAFB) the posteroinferior regions of the left ventricular endocardium are activated abnormally before the anterosuperior left ventricular area. After emerging from the posteroinferior division of the left bundle branch, the impulse first propagates in an inferior, rightward, and usually anterior direction for a short period of time. This orientation is responsible for the small Q waves in leads 1 and aVL and for the R waves in leads II, III, and aVF. (NCI)

C71040 LEFT ATRIAL P-mitrale An electrocardiographic finding suggesting underlying P-mitrale ENLARGEMENT hypertrophy or dilatation of the left atrium. Electrocardiographic criteria used for the diagnosis of left atrial abnormality may include a bifid p wave, a biphasic p wave and/or a p wave duration of greater than 0.12 seconds. (NCI)

C62269 LEFT BUNDLE BRANCH Left bundle An impairment of transmission of the cardiac Left Bundle Branch Block BLOCK branch block electrical impulse along the fibers of the left main bundle branch, or both the left anterior fascicle and left posterior fascicle. This conduction disturbance is characterized by wide (greater than 0.11s) QRS complexes. The diagnostic criteria consist of prolongation of the QRS complexes (over 0.11s) with neither a Q wave nor an S wave in lead V1 and in the properly placed V6. A wide R wave with a notch on its top (plateau) is seen in these leads. In hearts with an electrical (and anatomic) vertical position a small Q wave may be seen in AVL in the absence of MI. Right chest lead V1 may or may not show an initial R wave, but the latter should be present in lead V2. (NCI)

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 40 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C71150 - EGSTRESC - ECG Result Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C62268 LEFT POSTERIOR Left posterior An impairment of transmission of the cardiac Left Posterior Fascicular Block FASCICULAR BLOCK fascicular block electrical impulse along the fibers of the left posterior fascicle. In pure left posterior fascicular block (LPFB), the impulse emerges from the unblocked anterosuperior division, thus producing small q waves in leads II, III, and aVF. Thereafter, the impulse moves through the electrically predominant left ventricle in an inferior and rightward direction, thus explaining the S waves in leads I and aVL as well as the R waves in leads II, III, and aVF. (NCI)

C92231 LEFT VENTRICULAR Left Ventricular An electrocardiographic finding in which there is Left Ventricular Conduction Delay CONDUCTION DELAY Conduction evidence that electrical transmission through the left Delay ventricle is impaired.

C71076 LEFT VENTRICULAR Left Ventricular Electrocardiographic findings suggestive of a EKG Finding Left Ventricular HYPERTROPHY Hypertrophy hypertrophic left ventricle. (NCI) Hypertrophy

C71078 LOW QRS VOLTAGE Low QRS voltage An electrocardiographic finding of a QRS amplitude Low QRS Voltage less than or equal to 5mm in the limb leads or QRS amplitude less than or equal to 10mm in the precordial leads. (NCI)

C71050 MULTIFOCAL ATRIAL Multifocal atrial An electrocardiographic finding in which the electrical Multifocal Atrial Tachycardia TACHYCARDIA tachycardia axis of the p wave is variable and the rate is greater than 100 beats per minute. To meet criteria for multifocal atrial tachycardia, the p wave must exhibit three distinct morphologies on the rhythm strip. (NCI)

C71080 NON Q WAVE Non Q Wave A myocardial infarction in the absence of observable Q Non Q Wave Myocardial Infarction MYOCARDIAL Myocardial wave abnormalities in the ECG. (NCI) INFARCTION Infarction

C71031 NON-SPECIFIC ST-T Non-specific An electrocardiographic finding of changes in the ST Non-Specific ST-T Changes CHANGES ST-T changes segment and T wave that do not meet criteria for ischemia or infarction. (NCI)

C71053 NON-SUSTAINED Non-sustained An electrocardiographic finding of ventricular Non-Sustained Ventricular VENTRICULAR ventricular tachycardia less than 30 seconds in duration. (NCI) Tachycardia TACHYCARDIA tachycardia

C71032 NOTCHED T-WAVES Notched T-waves Any depression occurring in a positive t wave. (NCI) Notched T-Waves

C71064 OUTFLOW TRACT Outflow tract Right ventricular outflow tract tachycardia (RVOT) is Right Ventricular Outflow Tract VENTRICULAR ventricular the most common with a female predominance. It is Tachycardia TACHYCARDIA tachycardia often exercise induced or enhanced. The site of origin is the right ventricular outflow tract and hence the electrocardiographic appearance is that of left bundle branch block and inferior axis. The mechanism is thought to be abnormal automaticity that is sensitive to adenosine. (NCI)

C90430 P WAVE ABNORMALITY P Wave An electrocardiographic finding for the P wave that is P Wave Abnormality Abnormality atypical either for the shape, duration, amplitude, axis or polarity. Abnormality of the P wave signifies aberrant propagation of the electrical impulse through the atria. (NCI)

C90431 P WAVE NOTCHED P Wave Notched P waves with two peaks longer in duration than normal P Wave Notched and amplitude greater than normal. (NCI)

C92232 PACED ATRIAL AND Paced Atrial And An electrocardiographic finding in which both the Paced Atrial And Ventricular Rhythm VENTRICULAR RHYTHM Ventricular atrial and ventricular rhythm is controlled by an Rhythm electrical impulse from a mechanical cardiac pacemaker.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 41 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C71150 - EGSTRESC - ECG Result Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C92233 PACED ATRIAL RHYTHM Paced Atrial An electrocardiographic finding in which the atrial Paced Atrial Rhythm Rhythm rhythm is controlled by an electrical impulse from a mechanical cardiac pacemaker.

C88140 PACED RHYTHM Paced Rhythm; An electrocardiographic finding in which the cardiac Paced Rhythm Atrial and/or rhythm is controlled by an electrical impulse from a Ventricular mechanical cardiac pacemaker. Paced Rhythm

C92234 PACED VENTRICULAR Paced An electrocardiographic finding in which the Paced Ventricular Rhythm RHYTHM Ventricular ventricular rhythm is controlled by an electrical Rhythm impulse from a mechanical cardiac pacemaker.

C62250 PAROXYSMAL AV BLOCK Paroxysmal AV Sudden onset AV block, often associated with Paroxysmal Atrioventricular Block block preexisting conduction disorders. (NCI)

C34902 PAROXYSMAL Paroxysmal An episodic form of ventricular tachycardia, with Paroxysmal Ventricular Tachycardia VENTRICULAR Ventricular abrupt onset and termination. (NCI) TACHYCARDIA Tachycardia

C71033 POOR R WAVE Poor R Wave Lack of progression of R wave height across Poor R Wave Progression PROGRESSION Progression precordial leads. (NCI)

C71081 POSTERIOR WALL Posterior Wall Electrocardiographic finding showing an injury in Posterior Wall Myocardial MYOCARDIAL Myocardial leads corresponding to the anatomic region of the Infarction INFARCTION Infarction posterior wall of the heart. (NCI)

C62247 PR PROLONGATION PR prolongation A PR interval of more than 0.20 seconds in adults. Prolonged PR Interval (NCI)

C34940 PRE-EXCITATION Pre-excitation A condition characterized by the activation of the Pre-Excitation Syndrome whole or some part of the ventricle by the transmission of an atrial impulse along an accessory pathway rather than by way of the normal specific conduction system which includes a delay at the atrioventricular node. (NCI)

C62257 PREMATURE ATRIAL Premature atrial Ectopic impulses originating in the atria. (NCI) Atrial Premature Complex COMPLEXES complexes

C62256 PREMATURE PVC Ectopic impulses originating in the ventricles. (NCI) Ventricular Premature Complex VENTRICULAR COMPLEX

C71034 PROLONGED QT Prolonged QT A QT interval that is prolonged. The length of the QT Prolonged QT Interval interval varies with the heart rate. (NCI)

C71094 Q AXIS, LEFT AXIS Q Axis, Left axis Q axis from -30 to -90 degrees. (NCI) Q Axis Left Axis Deviation DEVIATION deviation

C71095 Q AXIS, RIGHT AXIS Q Axis, Right Q axis from +90 to +180 degrees. (NCI) Q Axis Right Axis Deviation DEVIATION axis deviation

C90440 QRS COMPLEX QRS Complex An electrocardiographic finding for the QRS complex QRS Complex Abnormality ABNORMALITY Abnormality that is atypical either for the shape, duration, amplitude, axis or polarity. (NCI)

C90441 QRS COMPLEX ABSENT QRS Complex A disturbance in the depolarization of the ventricular QRS Complex Absent Absent myocardium which leads to an absence of the QRS complex in the electrocardiogram tracing. (NCI)

C71096 QTCB PROLONGATION QTcB Corrected QT interval longer than 500 msec, in QTcB Prolongation Greater Than >500 MSEC prolongation accordance with Bazett's correction formula. (NCI) 500 msec >500 msec

C71097 QTCF PROLONGATION QTcF Corrected QT interval greater than 500 msec, in QTcF Prolongation Greater Than 500 >500 MSEC prolongation accordance with Fridericia's correction formula. (NCI) msec >500 msec

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 42 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C71150 - EGSTRESC - ECG Result Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C61395 R ON T PHENOMENON R on T An electrocardiographic finding phenomena in which R On T Phenomenon phenomenon the R wave occurs on top of the T wave; this can trigger ventricular fibrillation or ventricular tachycardia. (NCI)

C90443 R WAVE ABNORMALITY R Wave An abnormal R wave that is part of the QRS complex in R Wave Abnormality Abnormality an electrocardiographic recording, which occurs due to a disturbance in the depolarization mechanism of the ventricular myocardium. (NCI)

C90444 R WAVE NOTCHED R Wave Notched An R wave variant in which there is a small deflection R Wave Notched of the R wave, with changing polarity, within the QRS complex. (NCI)

C90450 RESPIRATORY SINUS Respiratory The inherent change of a subject's heart rate associated Respiratory Sinus Arrhythmia ARRHYTHMIA Sinus Arrhythmia with each excursion of breath, which can be traced in an electrocardiographic recording. (NCI)

C71041 RIGHT ATRIAL P-pulmonale An electrocardiographic finding suggesting underlying P-pulmonale ABNORMALITY hypertrophy or dilatation of the right atrium. Electrocardiographic criteria used for the diagnosis of right atrial abnormality may include a peaked p wave greater than 2.5 millimeters in amplitude in the inferior leads. (NCI)

C62270 RIGHT BUNDLE BRANCH Right Bundle An impairment of transmission of the cardiac Right Bundle Branch Block BLOCK Branch Block electrical impulse along the fibers of the right bundle branch. A "complete RBBB pattern" (with QRS duration > 0.11s) does not necessarily reflect the existence of a total conduction block in the right branch. This pattern only indicates that the entire or major parts of both ventricles are activated by the impulse emerging from the left branch. Thus, a significant degree of conduction delay ("high-grade" or "incomplete RBBB") can produce a similar pattern. (NCI)

C92235 RIGHT VENTRICULAR Right Ventricular An electrocardiographic finding in which there is Right Ventricular Conduction Delay CONDUCTION DELAY Conduction evidence that electrical transmission through the right Delay; Right ventricle is impaired. Ventricular Delay

C71077 RIGHT VENTRICULAR Right ventricular Electrocardiographic findings suggestive of an EKG Finding Right Ventricular HYPERTROPHY Hypertrophy enlarged right ventricle. (NCI) Hypertrophy

C92227 RSR PRIME RSR' An electrocardiographic finding in which there are two RSR' R waves, which are two deflections above the baseline resulting from a single ventricular depolarization. The first upward deflection in the complex is the R wave. The S is the first downward deflection. A second upward deflection is called the R-prime wave.

C90451 S WAVE ABNORMALITY S Wave An abnormal S wave that is part of the QRS complex in S Wave Abnormality Abnormality an electrocardiographic recording, which occurs due to a disturbance in the depolarization of the ventricular myocardium. (NCI)

C71082 SEPTAL MYOCARDIAL Septal Electrocardiographic findings suggesting an infarction Septal Myocardial Infarction INFARCTION myocardial in the anatomic location of the cardiac septum. (NCI) infarction

C62246 SHORT PR INTERVAL Short PR interval A PR interval of less than 0.12 seconds. (NCI) Short PR Interval

C62244 SICK SINUS SYNDROME Sick sinus A constellation of signs and symptoms which may Sick Sinus Syndrome syndrome include syncope, fatigue, dizziness, and alternating periods of bradycardia and atrial tachycardia, which is caused by sinoatrial node dysfunction. (NCI)

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 43 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C71150 - EGSTRESC - ECG Result Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C50553 SINOATRIAL EXIT BLOCK Sinoatrial exit A blockage of electrical conduction within the Sinoatrial Node Exit Block block sinoatrial node resulting in the failure of impulse transmission from the sinoatrial node. (NCI)

C62242 SINUS ARREST/PAUSE Sinus A failure of impulse formation in the sinus node. Sinus Sinus Arrest arrest/pause arrest is indistinguishable from third degree sinoatrial exit block on the standard ECG. (NCI)

C62239 SINUS ARRHYTHMIA Sinus arrhythmia Irregularity of the heartbeat due to a variation in the Sinus Arrhythmia sinus rhythm resulting in cyclic changes in the heart rate during breathing. This rhythm is most commonly seen with breathing due to fluctuations in parasympathetic vagal tone. During inspiration stretch receptors in the lungs stimulate the cardioinhibitory centers in the medulla via fibers in the vagus nerve. Irregularity of the heartbeat due to a variation in the sinus rhythm resulting in cyclic changes in the heart rate during breathing. This rhythm is most commonly seen with breathing due to fluctuations in parasympathetic vagal tone. During inspiration stretch receptors in the lungs stimulate the cardioinhibitory centers in the medulla via fibers in the vagus nerve. (NCI)

C26923 SINUS BRADYCARDIA Sinus bradycardia A heart rate of less than 60 beats per minute, with its Sinus Bradycardia origin in the sinus node. (NCI)

C62243 SINUS NODE Sinus node A derangement in the normal functioning of the Sinus Node Dysfunction DYSFUNCTION dysfunction sinoatrial node. Typically, SA node dysfunction is (BRADYCARDIA) (bradycardia) manifest as sinoatrial exit block or sinus arrest, but may present as an absolute or relative bradycardia in the presence of a stressor. It may be associated with bradycardia-tachycardia syndrome. (NCI)

C26889 SINUS TACHYCARDIA Sinus tachycardia A heart rate of more than 100 beats per minute, with Sinus Tachycardia its origin in the sinus node. (NCI)

C71027 ST DEPRESSION ST depression An electrocardiographic finding of ST segment ST Depression depression below the baseline, often described as up sloping, down sloping or horizontal. (NCI)

C71028 ST ELEVATION ST elevation An electrocardiographic finding of ST segment ST Elevation elevation above the baseline. (NCI)

C71029 ST ELEVATION ST elevation An electrocardiographic finding of ST changes ST Elevation Pericarditis PERICARDITIS pericarditis consistent with pericarditis. (NCI)

C71026 ST SEGMENT ST segment An electrocardiographic finding of the ST segment ST Segment Abnormality ABNORMALITY abnormality elevation or depression which is not indicative of ischemia or infarction. (NCI)

C35061 SUPRAVENTRICULAR Supraventricular A generic expression for any tachycardia that Supraventricular Tachycardia TACHYCARDIA tachycardia originates in the atria or the atrioventricular node. (NCI)

C71052 SUSTAINED VENTRICULAR Sustained An electrocardiographic finding of ventricular Sustained Ventricular Tachycardia TACHYCARDIA ventricular tachycardia greater than 30 seconds in duration. (NCI) tachycardia

C71083 T WAVE ABNORMALITY T wave An electrocardiographic finding of a T wave which T Wave Abnormality abnormality appears peaked, inverted, flattened or biphasic. (NCI)

C71085 T WAVE INVERSION T Wave Inversion An electrocardiographic finding of an inversion of the T Wave Inversion T wave from the expected axis. (NCI)

C71086 T WAVE PEAKED T wave peaked An electrocardiographic finding in which the T wave T Wave Peaked appears increased in amplitude and cresting at a point. (NCI)

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 44 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C71150 - EGSTRESC - ECG Result Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C71087 T WAVES BIPHASIC T waves biphasic An electrocardiographic finding in which the T wave is T Waves Biphasic asymmetric. (NCI)

C71088 T WAVES FLAT T waves flat An electrocardiographic finding in which the T wave T Waves Flat appears decreased in amplitude. (NCI)

C38029 TACHYCARDIA Tachycardia An abnormally rapid heartbeat, usually applied to a Tachycardia heart rate above 100 per minute.

C50779 TORSADES DE POINTES Torsades de An atypical rapid polymorphic ventricular tachycardia Torsades De Pointes pointes with a characteristic rotation of the QRS complex around the isoelectric baseline. In addition the QRS complex displays a periodic waxing and waning of amplitude on the electrogram. (NCI)

C71055 TRIGEMINY Trigeminy An electrocardiographic finding of normal QRS Trigeminy followed by a premature ventricular contraction; a rhythmic pairing of normal and abnormal beats originating from the ventricles in a 1-2 ratio. (NCI)

C71089 U WAVES U waves An electrocardiographic finding of a small hump U Waves following the T wave occurring during the final phase of Purkinje repolarization. (NCI)

C71059 VENTRICULAR Ventricular A condition characterized by a pattern of right bundle Brugada Syndrome ARRHYTHMIA arrhythmia branch block (RBBB) and ST-segment elevation within ASSOCIATED WITH associated with electrocardiogram (ECG) leads V1-V3 . This pattern BRUGADA SYNDROME Brugada emerges as a result of a defect in ion channel genes, syndrome resulting in abnormal electrophysiological activity in the right ventricle and a propensity to malignant tachyarrhythmias. (NCI)

C34786 VENTRICULAR Ventricular A ventricular arrhythmia characterized by syncopal Long QT Syndrome ARRHYTHMIA arrhythmia episodes and a long QT interval, sometimes leading to ASSOCIATED WITH LONG associated with sudden death due to paroxysmal ventricular arrhythmia. QT SYNDROME long QT This arrhythmia is associated with a prolongation of syndrome repolarization following depolarization of the cardiac ventricles. The prolongation of the Q-T interval combined with torsades de pointes manifests as several different forms; some may be acquired or congenital; some may lead to serious arrhythmia and sudden cardiac death. (NCI)

C71060 VENTRICULAR Ventricular Ventricular tachyarrhythmias occurring in association Short QT Syndrome ARRHYTHMIA arrhythmia with short QT syndrome. (NCI) ASSOCIATED WITH SHORT associated with QT SYNDROME short QT syndrome

C62259 VENTRICULAR COUPLET Ventricular Two sequential ventricular premature complexes. An Ventricular Couplet couplet otherwise normal finding, but possibly indicative of electrical heart disease particularly in comparison with a single ventricular premature complexes. (NCI)

C90483 VENTRICULAR ESCAPE Ventricular A compensatory ectopic beat that occurs in the Ventricular Escape Beat BEAT Escape Beat ventricle after a pause in the ventricular rhythm, which is due to an absence in electrical activity to the ventricles. (NCI)

C50799 VENTRICULAR Ventricular An arrhythmia characterized by an irregular pattern of Ventricular Fibrillation FIBRILLATION fibrillation high or low-amplitude waves that cannot be differentiated into QRS complexes or T waves. These electrocardiographic waves occur as a result of fibrillary contractions of the ventricular muscle due to rapid repetitive excitation of myocardial fibers without coordinated contraction of the ventricle. (NCI)

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 45 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C71150 - EGSTRESC - ECG Result Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C50800 VENTRICULAR FLUTTER Ventricular A ventricular tachyarrhythmia characterized by a high Ventricular Flutter flutter ventricular rate (180 and 250 beats per minute) with a regular rhythm. The electrocardiogram shows large oscillating sine wave-like complexes occurring as a result of QRS complexes and T waves being merged. The P wave is not visible. (NCI)

C71084 VENTRICULAR Ventricular Electrocardiographic findings suggestive of enlarged Ventricular Hypertrophy HYPERTROPHY Hypertrophy cardiac ventricles. (NCI)

C50802 VENTRICULAR Ventricular A tachycardia arising distal to bundle of His, with a Ventricular Tachycardia TACHYCARDIA tachycardia rate greater than 100 beats per minute. (NCI)

C71056 VENTRICULAR Ventricular Multiple, temporally related, episodes of ventricular Ventricular Tachycardia Storm TACHYCARDIA STORM tachycardia tachycardia or fibrillation, occurring three or more storm times in a 24 hour period. (NCI)

C62234 VENTRICULAR Ventricular A ventricular tachycardia in which the ventricular Monomorphic Ventricular TACHYCARDIA, tachycardia, activation sequence is constant. The morphology of the Tachycardia MONOMORPHIC monomorphic electrocardiographic waveform is unchanging and is referred to as monomorphic. (NCI)

C62236 VENTRICULAR Ventricular A ventricular tachycardia in which the ventricular Polymorphic Ventricular TACHYCARDIA, tachycardia, activation sequence is variable. The morphology of the Tachycardia POLYMORPHIC polymorphic electrocardiographic waveform is variable and is referred to as polymorphic. (NCI)

C71058 VERAPAMIL-SENSITIVE Verapamil-sensit A well-recognized condition that is believed to result Verapamil-Sensitive Ventricular VENTRICULAR ive ventricular from triggered activity. Despite its uniform response Tachycardia TACHYCARDIA tachycardia to verapamil, however, this uncommon form of ventricular tachycardia may not be as homogeneous a condition as first believed. (NCI)

C62240 WANDERING ATRIAL Wandering atrial A condition characterized by the site of origin of Wandering Atrial Pacemaker PACEMAKER pacemaker impulses, controlling the heart rate, changing within the atria, including the sinus node. Variations within P waves and PR intervals occur and an irregular rate of impulse formation is observed. (NCI)

C71090 WIDE QRS TACHYCARDIA Wide QRS An electrocardiographic finding of a QRS complex. Wide QRS Tachycardia tachycardia (NCI)

C35132 WOLFF-PARKINSON-WHIT Wolff-Parkinson A type of ventricular pre-excitation resulting from the Wolff-Parkinson-White Syndrome E SYNDROME -White syndrome activation of an accessory pathway known as the Bundle of Kent. This pathway presents an abnormal electrical communication from the atria to the ventricles. Wolff-Parkinson-White syndrome is characterized by a short PR interval and a long QRS interval with a delta wave. (NCI)

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 46 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C71152 - EGTEST - ECG Test Name Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C41255 Interpretation Interpretation An act or process of elucidation; explication, or Interpretation explanation of the meaning of the event or thing via the assignment of objects from the domain to the constants of a formal language, truth-values to the proposition symbols, truth-functions to the connectives, other functions to the function symbols, and extensions to the predicates, if any. The assignments are result of human logic application and are not native to the symbols of the formal language.

C62118 JTcB - Bazett's Correction JTcB - Bazett's A formula which takes into account the physiologic JTcB-Bazett's Correction Formula Formula Correction shortening of the JT interval which occurs as the heart Formula rate increases, permitting comparison of the JT interval across a range of rates. It is mathematically defined as: JTcB = JT/SqRootRR(seconds) and theoretically corrects the JT interval to that which would be observed at a heart rate of 1 cycle per second. (NCI)

C62119 JTcF - Fridericia's Correction JTcF - A formula which takes into account the physiologic JTcF-Fridericia's Correction Formula Fridericia's shortening of the JT interval which occurs as the heart Formula Correction rate increases, permitting comparison of the JT Formula interval across a range of rates. It is mathematically defined as: JTcF = JT/CubeRootRR(seconds) and theoretically corrects the JT interval to that which would be observed at a heart rate of 1 cycle per second. (NCI)

C62120 JTcLC - Linear Correction JTcLC - Linear A formula which takes into account the physiologic JTcLC-Linear Correction Formula Formula Correction shortening of the JT interval which occurs as the heart Formula rate increases, permitting comparison of the JT interval across a range of rates. The linear correction formula uses population-based data obtained and validated using a large cohort of subjects. Using this method, the corrected JT interval is independent of the ventricular rate. (NCI)

C100390 QRS Duration Ventricular QRS Duration The average (mean) duration (time) of the QRS EKG Mean QRS Duration Paced Ventricular interval, obtained from a set of measurements of the Ventricular Paced Paced QRS interval while the ventricle rhythm is controlled by an electrical impulse from a mechanical cardiac pacemaker. The QRS interval is defined as the time from the beginning of the QRS complex to the end of the QRS complex, representing the time it takes for the ventricles to depolarize.

C100391 QT Interval, Corrected QT Interval, The time interval between the start of the Q wave and Corrected QT Interval Corrected the end of the T wave in the cardiac cycle as corrected with a non-specified correction formula.

C62112 QTcB - Bazett's Correction QTcB - Bazett's A formula which takes into account the physiologic QTcB-Bazett's Correction Formula Formula Correction shortening of the QT interval which occurs as the heart Formula rate increases, permitting comparison of the QT interval across a range of rates. It is mathematically defined as: QTcB = QT/SqRootRR(seconds) and theoretically corrects the QT interval to that which would be observed at a heart rate of 1 cycle per second. (NCI)

C62113 QTcF - Fridericia's Correction QTcF - A formula which takes into account the physiologic QTcF-Fridericia's Correction Formula Fridericia's shortening of the QT interval which occurs as the heart Formula Correction rate increases, permitting comparison of the QT Formula interval across a range of rates. It is mathematically defined as: QTcF = QT/CubeRootRR(seconds) and theoretically corrects the QT interval to that which would be observed at a heart rate of 1 cycle per second. (NCI)

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 47 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C71152 - EGTEST - ECG Test Name Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C62114 QTcLC - Linear Correction QTcLC - Linear A formula which takes into account the physiologic QTcLC-Linear Correction Formula Formula Correction shortening of the QT interval which occurs as the heart Formula rate increases, permitting comparison of the QT interval across a range of rates. The linear correction formula uses population-based data obtained and validated using a large cohort of subjects. This method theoretically corrects the QT interval to that which would be observed at a heart rate of 1 cycle per second. (NCI)

C90442 QTcV - Van de Water's QTcV - Van de A mathematic formula defined as: QTcV Van de Water's Correction Correction Formula Water's QTcV = QT-0.087[(60/Heart Rate)-1](seconds). It Formula Correction permits comparison of the QT interval across a range Formula of rates, while accounting for the progressive shortening of the QT interval which occurs as the heart rate increases. (NCI)

C39779 Summary (Max) Heart Rate Summary (Max) The minimum time between successive cycles of Maximum Heart Rate Heart Rate contraction and subsequent relaxation of the heart, usually expressed as beats per minute, obtained from a set of measurements of the heart rate. (NCI)

C62117 Summary (Max) JT Interval Summary (Max) The maximum duration (time) of the JT interval, EKG Maximum JT Duration JT Interval obtained from a set of measurements of the JT interval. The JT interval is defined as the time from the J point (end of ventricular depolarization, the point at which the QRS meets the ST segment) to the end of the T wave (representing the end of ventricular repolarization). (NCI)

C62131 Summary (Max) PR Duration Summary (Max) The maximum duration (time) of the PR interval, EKG Maximum PR Duration PR Duration obtained from a set of measurements of the PR interval. The PR interval is defined as the time from the beginning of the P wave (representing the onset of atrial depolarization) to the beginning of the R wave (representing the onset of ventricular depolarization). In some cases, a Q wave will precede the R wave, in which case the PR interval is measured from the beginning of the P wave to the beginning of the Q wave. (NCI)

C62135 Summary (Max) QT Duration Summary (Max) The maximum duration (time) of the QT interval, EKG Maximum QT Duration QT Duration obtained from a set of measurements of the QT interval. The QT interval is defined as the time from the beginning of the QRS complex to the end of the T wave, representing the time it takes for the ventricles to depolarize and subsequently repolarize. In some cases, the Q wave will be absent, in which case the QT interval is measured from the beginning of the R wave to the end of the T wave. (NCI)

C62094 Summary (Max) RR Duration Summary (Max) The maximum duration (time) between successive EKG Maximum RR Duration RR Duration peaks of R waves in a particular set of RR intervals. (NCI)

C62163 Summary (Max) ST Summary (Max) The maximum depression (negative deflection from EKG Maximum ST Segment Depression ST Depression baseline, usually measured in mm) of the ST segment, Depression obtained from a set of measurements of the depression of the ST segment. (NCI)

C62157 Summary (Max) ST Deviation Summary (Max) The maximum deviation (distance from baseline, EKG Maximum ST Deviation ST Deviation positive or negative, usually measured in mm) of the ST segment, obtained from a set of measurements of the deviation of the ST segment. (NCI)

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 48 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C71152 - EGTEST - ECG Test Name Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C62160 Summary (Max) ST Elevation Summary (Max) The maximum elevation (positive deflection from EKG Maximum ST Segment ST Elevation baseline, usually measured in mm) of the ST segment, Elevation obtained from a set of measurements of the elevation of the ST segment. (NCI)

C62154 Summary (Max) Ventricular Summary (Max) The maximum time between successive cycles of Maximum Ventricular Heart Rate Rate Ventricular Rate contraction and subsequent relaxation of the ventricles, usually expressed as beats per minute, obtained from a set of measurements of the ventricular rate. (NCI)

C62095 Summary (Mean) Heart Rate Summary (Mean) The average (mean) number of cycles of contraction Mean Heart Rate Heart Rate and subsequent relaxation of the heart, usually expressed as beats per minute, obtained from a set of measurements of the heart rate. (NCI)

C62115 Summary (Mean) JT Interval Summary (Mean) The average (mean) duration (time) of the JT interval, EKG Mean JT Duration JT Interval obtained from a set of measurements of the JT interval. The JT interval is defined as the time from the J point (end of ventricular depolarization, the point at which the QRS meets the ST segment) to the end of the T wave (representing the end of ventricular repolarization). (NCI)

C62121 Summary (Mean) P Axis Summary (Mean) The mean (average) direction (range -180 degrees to EKG Mean P Axis P Axis 180 degrees) of the electrical potential generated by atrial depolarization in a particular plane (usually the frontal plane). (NCI)

C62123 Summary (Mean) P Wave Summary (Mean) The average (mean) duration (time) from the onset of EKG Mean P Wave Duration Duration P Wave Duration atrial depolarization to the completion of atrial depolarization (length of the P wave), obtained from a set of measurements of the time from beginning to end of atrial depolarization. (NCI)

C62124 Summary (Mean) P Wave Summary (Mean) The average (mean) height (usually measured in mm) EKG Mean P Wave Height Height P Wave Height of the maximum deflection from baseline of the P wave (representing atrial depolarization), obtained from a set of measurements of the P wave, from a single lead or set of leads. Typically this measurement is obtained by analysis of Lead II. (NCI)

C62086 Summary (Mean) PR Duration Summary (Mean) The average (mean) duration (time) of the PR interval, EKG Mean PR Duration PR Duration obtained from a set of measurements of the PR interval. The PR interval is defined as the time from the beginning of the P wave (representing the onset of atrial depolarization) to the beginning of the R wave (representing the onset of ventricular depolarization). In some cases, a Q wave will precede the R wave, in which case the PR interval is measured from the beginning of the P wave to the beginning of the Q wave. (NCI)

C62132 Summary (Mean) QRS Axis Summary (Mean) The mean (average) direction of the electrical Mean QRS Axis QRS Axis potential generated by ventricular depolarization. (NCI)

C62087 Summary (Mean) QRS Summary (Mean) The average (mean) duration (time) of the QRS EKG Mean QRS Duration Duration QRS Duration interval, obtained from a set of measurements of the QRS interval. The QRS interval is defined as the time from the beginning of the QRS complex to the end of the QRS complex, representing the time it takes for the ventricles to depolarize. (NCI)

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 49 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C71152 - EGTEST - ECG Test Name Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C62089 Summary (Mean) QT Duration Summary (Mean) The average (mean) duration (time) of the QT interval, EKG Mean QT Duration QT Duration obtained from a set of measurements of the QT interval. The QT interval is defined as the time from the beginning of the QRS complex to the end of the T wave, representing the time it takes for the ventricles to depolarize and subsequently repolarize. In some cases, the Q wave will be absent, in which case the QT interval is measured from the beginning of the R wave to the end of the T wave. (NCI)

C62136 Summary (Mean) R Wave Summary (Mean) The average (mean) amplitude (usually in mm) of the R EKG Mean R Wave Amplitude Amplitude R Wave wave, obtained from a set of measurements of the R Amplitude wave, in a particular lead or set of leads. (NCI)

C62144 Summary (Mean) R+S Summary (Mean) The average (mean) amplitude (usually in mm) of the EKG Mean R+S Amplitude Amplitude R+S Amplitude summation of the R and S waves, obtained from a set of measurements of the R and S waves, in a particular lead or set of leads. (NCI)

C62090 Summary (Mean) RR Duration Summary (Mean) The average (mean) duration (time) of the RR interval, EKG Mean RR Duration RR Duration obtained from a set of measurements of the RR interval. The RR interval is defined as the time between successive peaks of the R wave and can be used to measure the ventricular rate. (NCI)

C62137 Summary (Mean) S Wave Summary (Mean) The average (mean) amplitude (usually in mm) of the S EKG Mean S Wave Amplitude Amplitude S Wave wave, obtained from a set of measurements of the S Amplitude wave, in a particular lead or set of leads. (NCI)

C62161 Summary (Mean) ST Summary (Mean) The average (mean) depression (negative deflection EKG Mean ST Segment Depression Depression ST Depression from baseline, usually measured in mm) of the ST segment, obtained from a set of measurements of the depression of the ST segment. (NCI)

C62155 Summary (Mean) ST Summary (Mean) The average (mean) deviation (distance from baseline, EKG Mean ST Deviation Deviation ST Deviation positive or negative, usually measured in mm) of the ST segment, obtained from a set of measurements of the deviation of the ST segment. (NCI)

C62158 Summary (Mean) ST Elevation Summary (Mean) The average (mean) elevation (positive deflection from EKG Mean ST Segment Elevation ST Elevation baseline, usually measured in mm) of the ST segment, obtained from a set of measurements of the elevation of the ST segment. (NCI)

C62145 Summary (Mean) ST Segment Summary (Mean) The average (mean) duration (time) from the end of EKG Mean ST Segment Duration Duration ST Segment ventricular depolarization (end of QRS complex) to Duration the end of ventricular repolarization (end of the T wave). (NCI)

C62148 Summary (Mean) T Wave Area Summary (Mean) The average (mean) area under the curve of the EKG Mean T Wave Area T Wave Area deflection from baseline of the T wave (representing ventricular repolarization), obtained from a set of measurements of the T wave, from a single lead or set of leads. (NCI)

C62146 Summary (Mean) T Wave Axis Summary (Mean) The mean (average) direction of the electrical EKG Mean T Wave Axis T Wave Axis potential generated by ventricular repolarization. (NCI)

C62147 Summary (Mean) T Wave Summary (Mean) The average (mean) duration (time) from the onset of EKG Mean T Wave Duration Duration T Wave Duration ventricular repolarization to the completion of ventricular repolarization (length of the T wave), obtained from a set of measurements of the time from beginning to end of ventricular repolarization. (NCI)

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 50 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C71152 - EGTEST - ECG Test Name Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C62149 Summary (Mean) T Wave Summary (Mean) The average (mean) height (usually measured in mm) EKG Mean T Wave Height Height T Wave Height of the maximum deflection from baseline of the T wave (representing ventricular repolarization), obtained from a set of measurements of the T wave, from a single lead or set of leads. (NCI)

C62152 Summary (Mean) Ventricular Summary (Mean) The average (mean) number of cycles of contraction Mean Ventricular Heart Rate Rate Ventricular Rate and subsequent relaxation of the ventricles, usually expressed as beats per minute, obtained from a set of measurements of the ventricular rate. (NCI)

C62096 Summary (Min) Heart Rate Summary (Min) The maximum time between successive cycles of Minimum Heart Rate Heart Rate contraction and subsequent relaxation of the heart, usually expressed as beats per minute, obtained from a set of measurements of the heart rate. (NCI)

C62116 Summary (Min) JT Interval Summary (Min) The minimum duration (time) of the JT interval, EKG Minimum JT Duration JT Interval obtained from a set of measurements of the JT interval. The JT interval is defined as the time from the J point (end of ventricular depolarization, the point at which the QRS meets the ST segment) to the end of the T wave (representing the end of ventricular repolarization). (NCI)

C62125 Summary (Min) PR Duration Summary (Min) The minimum duration (time) of the PR interval, EKG Minimum PR Duration PR Duration obtained from a set of measurements of the PR interval. The PR interval is defined as the time from the beginning of the P wave (representing the onset of atrial depolarization) to the beginning of the R wave (representing the onset of ventricular depolarization). In some cases, a Q wave will precede the R wave, in which case the PR interval is measured from the beginning of the P wave to the beginning of the Q wave. (NCI)

C62133 Summary (Min) QT Duration Summary (Min) The minimum duration (time) of the QT interval, Minimum QT Duration QT Duration obtained from a set of measurements of the QT interval. The QT interval is defined as the time from the beginning of the QRS complex to the end of the T wave, representing the time it takes for the ventricles to depolarize and subsequently repolarize. In some cases, the Q wave will be absent, in which case the QT interval is measured from the beginning of the R wave to the end of the T wave. (NCI)

C62093 Summary (Min) RR Duration Summary (Min) The minimum duration (time) between successive EKG Minimum RR Duration RR Duration peaks of R waves in a particular set of RR intervals. (NCI)

C62162 Summary (Min) ST Summary (Min) The minimum depression (negative deflection from EKG Minimum ST Segment Depression ST Depression baseline, usually measured in mm) of the ST segment, Depression obtained from a set of measurements of the depression of the ST segment. (NCI)

C62156 Summary (Min) ST Deviation Summary (Min) The minimum deviation (distance from baseline, EKG Minimum ST Deviation ST Deviation positive or negative, usually measured in mm) of the ST segment, obtained from a set of measurements of the deviation of the ST segment. (NCI)

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 51 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C71152 - EGTEST - ECG Test Name Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C62159 Summary (Min) ST Elevation Summary (Min) The minimum elevation (positive deflection from EKG Minimum ST Segment ST Elevation baseline, usually measured in mm) of the ST segment, Elevation obtained from a set of measurements of the elevation of the ST segment. (NCI)

C62153 Summary (Min) Ventricular Summary (Min) The minimum time between successive cycles of Minimum Ventricular Heart Rate Rate Ventricular Rate contraction and subsequent relaxation of the ventricles, usually expressed as beats per minute, obtained from a set of measurements of the ventricular rate. (NCI)

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 52 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C71153 - EGTESTCD - ECG Test Code Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C39779 HRMAX Summary (Max) The minimum time between successive cycles of Maximum Heart Rate Heart Rate contraction and subsequent relaxation of the heart, usually expressed as beats per minute, obtained from a set of measurements of the heart rate. (NCI)

C62095 HRMEAN Summary (Mean) The average (mean) number of cycles of contraction Mean Heart Rate Heart Rate and subsequent relaxation of the heart, usually expressed as beats per minute, obtained from a set of measurements of the heart rate. (NCI)

C62096 HRMIN Summary (Min) The maximum time between successive cycles of Minimum Heart Rate Heart Rate contraction and subsequent relaxation of the heart, usually expressed as beats per minute, obtained from a set of measurements of the heart rate. (NCI)

C41255 INTP Interpretation An act or process of elucidation; explication, or Interpretation explanation of the meaning of the event or thing via the assignment of objects from the domain to the constants of a formal language, truth-values to the proposition symbols, truth-functions to the connectives, other functions to the function symbols, and extensions to the predicates, if any. The assignments are result of human logic application and are not native to the symbols of the formal language.

C62118 JTCB JTcB - Bazett's A formula which takes into account the physiologic JTcB-Bazett's Correction Formula Correction shortening of the JT interval which occurs as the heart Formula rate increases, permitting comparison of the JT interval across a range of rates. It is mathematically defined as: JTcB = JT/SqRootRR(seconds) and theoretically corrects the JT interval to that which would be observed at a heart rate of 1 cycle per second. (NCI)

C62119 JTCF JTcF - A formula which takes into account the physiologic JTcF-Fridericia's Correction Fridericia's shortening of the JT interval which occurs as the heart Formula Correction rate increases, permitting comparison of the JT Formula interval across a range of rates. It is mathematically defined as: JTcF = JT/CubeRootRR(seconds) and theoretically corrects the JT interval to that which would be observed at a heart rate of 1 cycle per second. (NCI)

C62120 JTCLC JTcLC - Linear A formula which takes into account the physiologic JTcLC-Linear Correction Formula Correction shortening of the JT interval which occurs as the heart Formula rate increases, permitting comparison of the JT interval across a range of rates. The linear correction formula uses population-based data obtained and validated using a large cohort of subjects. Using this method, the corrected JT interval is independent of the ventricular rate. (NCI)

C62117 JTMAX Summary (Max) The maximum duration (time) of the JT interval, EKG Maximum JT Duration JT Interval obtained from a set of measurements of the JT interval. The JT interval is defined as the time from the J point (end of ventricular depolarization, the point at which the QRS meets the ST segment) to the end of the T wave (representing the end of ventricular repolarization). (NCI)

C62115 JTMEAN Summary (Mean) The average (mean) duration (time) of the JT interval, EKG Mean JT Duration JT Interval obtained from a set of measurements of the JT interval. The JT interval is defined as the time from the J point (end of ventricular depolarization, the point at which the QRS meets the ST segment) to the end of the T wave (representing the end of ventricular repolarization). (NCI)

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 53 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C71153 - EGTESTCD - ECG Test Code Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C62116 JTMIN Summary (Min) The minimum duration (time) of the JT interval, EKG Minimum JT Duration JT Interval obtained from a set of measurements of the JT interval. The JT interval is defined as the time from the J point (end of ventricular depolarization, the point at which the QRS meets the ST segment) to the end of the T wave (representing the end of ventricular repolarization). (NCI)

C62121 PAXIS Summary (Mean) The mean (average) direction (range -180 degrees to EKG Mean P Axis P Axis 180 degrees) of the electrical potential generated by atrial depolarization in a particular plane (usually the frontal plane). (NCI)

C62131 PRMAX Summary (Max) The maximum duration (time) of the PR interval, EKG Maximum PR Duration PR Duration obtained from a set of measurements of the PR interval. The PR interval is defined as the time from the beginning of the P wave (representing the onset of atrial depolarization) to the beginning of the R wave (representing the onset of ventricular depolarization). In some cases, a Q wave will precede the R wave, in which case the PR interval is measured from the beginning of the P wave to the beginning of the Q wave. (NCI)

C62086 PRMEAN Summary (Mean) The average (mean) duration (time) of the PR interval, EKG Mean PR Duration PR Duration obtained from a set of measurements of the PR interval. The PR interval is defined as the time from the beginning of the P wave (representing the onset of atrial depolarization) to the beginning of the R wave (representing the onset of ventricular depolarization). In some cases, a Q wave will precede the R wave, in which case the PR interval is measured from the beginning of the P wave to the beginning of the Q wave. (NCI)

C62125 PRMIN Summary (Min) The minimum duration (time) of the PR interval, EKG Minimum PR Duration PR Duration obtained from a set of measurements of the PR interval. The PR interval is defined as the time from the beginning of the P wave (representing the onset of atrial depolarization) to the beginning of the R wave (representing the onset of ventricular depolarization). In some cases, a Q wave will precede the R wave, in which case the PR interval is measured from the beginning of the P wave to the beginning of the Q wave. (NCI)

C62123 PWAVEDUR Summary (Mean) The average (mean) duration (time) from the onset of EKG Mean P Wave Duration P Wave Duration atrial depolarization to the completion of atrial depolarization (length of the P wave), obtained from a set of measurements of the time from beginning to end of atrial depolarization. (NCI)

C62124 PWAVEHT Summary (Mean) The average (mean) height (usually measured in mm) EKG Mean P Wave Height P Wave Height of the maximum deflection from baseline of the P wave (representing atrial depolarization), obtained from a set of measurements of the P wave, from a single lead or set of leads. Typically this measurement is obtained by analysis of Lead II. (NCI)

C62132 QRSAXIS Summary (Mean) The mean (average) direction of the electrical Mean QRS Axis QRS Axis potential generated by ventricular depolarization. (NCI)

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 54 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C71153 - EGTESTCD - ECG Test Code Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C62087 QRSDUR Summary (Mean) The average (mean) duration (time) of the QRS EKG Mean QRS Duration QRS Duration interval, obtained from a set of measurements of the QRS interval. The QRS interval is defined as the time from the beginning of the QRS complex to the end of the QRS complex, representing the time it takes for the ventricles to depolarize. (NCI)

C100390 QRSDURVP QRS Duration The average (mean) duration (time) of the QRS EKG Mean QRS Duration Ventricular interval, obtained from a set of measurements of the Ventricular Paced Paced QRS interval while the ventricle rhythm is controlled by an electrical impulse from a mechanical cardiac pacemaker. The QRS interval is defined as the time from the beginning of the QRS complex to the end of the QRS complex, representing the time it takes for the ventricles to depolarize.

C100391 QTC QT Interval, The time interval between the start of the Q wave and Corrected QT Interval Corrected the end of the T wave in the cardiac cycle as corrected with a non-specified correction formula.

C62112 QTCB QTcB - Bazett's A formula which takes into account the physiologic QTcB-Bazett's Correction Formula Correction shortening of the QT interval which occurs as the heart Formula rate increases, permitting comparison of the QT interval across a range of rates. It is mathematically defined as: QTcB = QT/SqRootRR(seconds) and theoretically corrects the QT interval to that which would be observed at a heart rate of 1 cycle per second. (NCI)

C62113 QTCF QTcF - A formula which takes into account the physiologic QTcF-Fridericia's Correction Fridericia's shortening of the QT interval which occurs as the heart Formula Correction rate increases, permitting comparison of the QT Formula interval across a range of rates. It is mathematically defined as: QTcF = QT/CubeRootRR(seconds) and theoretically corrects the QT interval to that which would be observed at a heart rate of 1 cycle per second. (NCI)

C62114 QTCLC QTcLC - Linear A formula which takes into account the physiologic QTcLC-Linear Correction Formula Correction shortening of the QT interval which occurs as the heart Formula rate increases, permitting comparison of the QT interval across a range of rates. The linear correction formula uses population-based data obtained and validated using a large cohort of subjects. This method theoretically corrects the QT interval to that which would be observed at a heart rate of 1 cycle per second. (NCI)

C90442 QTCV QTcV - Van de A mathematic formula defined as: QTcV Van de Water's Correction Water's QTcV = QT-0.087[(60/Heart Rate)-1](seconds). It Formula Correction permits comparison of the QT interval across a range Formula of rates, while accounting for the progressive shortening of the QT interval which occurs as the heart rate increases. (NCI)

C62135 QTMAX Summary (Max) The maximum duration (time) of the QT interval, EKG Maximum QT Duration QT Duration obtained from a set of measurements of the QT interval. The QT interval is defined as the time from the beginning of the QRS complex to the end of the T wave, representing the time it takes for the ventricles to depolarize and subsequently repolarize. In some cases, the Q wave will be absent, in which case the QT interval is measured from the beginning of the R wave to the end of the T wave. (NCI)

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 55 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C71153 - EGTESTCD - ECG Test Code Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C62089 QTMEAN Summary (Mean) The average (mean) duration (time) of the QT interval, EKG Mean QT Duration QT Duration obtained from a set of measurements of the QT interval. The QT interval is defined as the time from the beginning of the QRS complex to the end of the T wave, representing the time it takes for the ventricles to depolarize and subsequently repolarize. In some cases, the Q wave will be absent, in which case the QT interval is measured from the beginning of the R wave to the end of the T wave. (NCI)

C62133 QTMIN Summary (Min) The minimum duration (time) of the QT interval, Minimum QT Duration QT Duration obtained from a set of measurements of the QT interval. The QT interval is defined as the time from the beginning of the QRS complex to the end of the T wave, representing the time it takes for the ventricles to depolarize and subsequently repolarize. In some cases, the Q wave will be absent, in which case the QT interval is measured from the beginning of the R wave to the end of the T wave. (NCI)

C62094 RRMAX Summary (Max) The maximum duration (time) between successive EKG Maximum RR Duration RR Duration peaks of R waves in a particular set of RR intervals. (NCI)

C62090 RRMEAN Summary (Mean) The average (mean) duration (time) of the RR interval, EKG Mean RR Duration RR Duration obtained from a set of measurements of the RR interval. The RR interval is defined as the time between successive peaks of the R wave and can be used to measure the ventricular rate. (NCI)

C62093 RRMIN Summary (Min) The minimum duration (time) between successive EKG Minimum RR Duration RR Duration peaks of R waves in a particular set of RR intervals. (NCI)

C62144 RSAMP Summary (Mean) The average (mean) amplitude (usually in mm) of the EKG Mean R+S Amplitude R+S Amplitude summation of the R and S waves, obtained from a set of measurements of the R and S waves, in a particular lead or set of leads. (NCI)

C62136 RWAVEAMP Summary (Mean) The average (mean) amplitude (usually in mm) of the R EKG Mean R Wave Amplitude R Wave wave, obtained from a set of measurements of the R Amplitude wave, in a particular lead or set of leads. (NCI)

C62163 STDPMAX Summary (Max) The maximum depression (negative deflection from EKG Maximum ST Segment ST Depression baseline, usually measured in mm) of the ST segment, Depression obtained from a set of measurements of the depression of the ST segment. (NCI)

C62161 STDPMEAN Summary (Mean) The average (mean) depression (negative deflection EKG Mean ST Segment Depression ST Depression from baseline, usually measured in mm) of the ST segment, obtained from a set of measurements of the depression of the ST segment. (NCI)

C62162 STDPMIN Summary (Min) The minimum depression (negative deflection from EKG Minimum ST Segment ST Depression baseline, usually measured in mm) of the ST segment, Depression obtained from a set of measurements of the depression of the ST segment. (NCI)

C62157 STDVMAX Summary (Max) The maximum deviation (distance from baseline, EKG Maximum ST Deviation ST Deviation positive or negative, usually measured in mm) of the ST segment, obtained from a set of measurements of the deviation of the ST segment. (NCI)

C62155 STDVMEAN Summary (Mean) The average (mean) deviation (distance from baseline, EKG Mean ST Deviation ST Deviation positive or negative, usually measured in mm) of the ST segment, obtained from a set of measurements of the deviation of the ST segment. (NCI)

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 56 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C71153 - EGTESTCD - ECG Test Code Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C62156 STDVMIN Summary (Min) The minimum deviation (distance from baseline, EKG Minimum ST Deviation ST Deviation positive or negative, usually measured in mm) of the ST segment, obtained from a set of measurements of the deviation of the ST segment. (NCI)

C62160 STELMAX Summary (Max) The maximum elevation (positive deflection from EKG Maximum ST Segment ST Elevation baseline, usually measured in mm) of the ST segment, Elevation obtained from a set of measurements of the elevation of the ST segment. (NCI)

C62158 STELMEAN Summary (Mean) The average (mean) elevation (positive deflection from EKG Mean ST Segment Elevation ST Elevation baseline, usually measured in mm) of the ST segment, obtained from a set of measurements of the elevation of the ST segment. (NCI)

C62159 STELMIN Summary (Min) The minimum elevation (positive deflection from EKG Minimum ST Segment ST Elevation baseline, usually measured in mm) of the ST segment, Elevation obtained from a set of measurements of the elevation of the ST segment. (NCI)

C62145 STSEGDUR Summary (Mean) The duration (time) of the ST segment, measured from EKG Mean ST Segment Duration ST Segment the J point at the end of the QRS complex to the Duration beginning of the T wave. (NCI)

C62137 SWAVEAMP Summary (Mean) The average (mean) amplitude (usually in mm) of the S EKG Mean S Wave Amplitude S Wave wave, obtained from a set of measurements of the S Amplitude wave, in a particular lead or set of leads. (NCI)

C62146 TAXIS Summary (Mean) The mean (average) direction of the electrical EKG Mean T Wave Axis T Wave Axis potential generated by ventricular repolarization. (NCI)

C62148 TWAVAREA Summary (Mean) The average (mean) area under the curve of the EKG Mean T Wave Area T Wave Area deflection from baseline of the T wave (representing ventricular repolarization), obtained from a set of measurements of the T wave, from a single lead or set of leads. (NCI)

C62147 TWAVEDUR Summary (Mean) The average (mean) duration (time) from the onset of EKG Mean T Wave Duration T Wave Duration ventricular repolarization to the completion of ventricular repolarization (length of the T wave), obtained from a set of measurements of the time from beginning to end of ventricular repolarization. (NCI)

C62149 TWAVEHT Summary (Mean) The average (mean) height (usually measured in mm) EKG Mean T Wave Height T Wave Height of the maximum deflection from baseline of the T wave (representing ventricular repolarization), obtained from a set of measurements of the T wave, from a single lead or set of leads. (NCI)

C62154 VRMAX Summary (Max) The maximum time between successive cycles of Maximum Ventricular Heart Rate Ventricular Rate contraction and subsequent relaxation of the ventricles, usually expressed as beats per minute, obtained from a set of measurements of the ventricular rate. (NCI)

C62152 VRMEAN Summary (Mean) The average (mean) number of cycles of contraction Mean Ventricular Heart Rate Ventricular Rate and subsequent relaxation of the ventricles, usually expressed as beats per minute, obtained from a set of measurements of the ventricular rate. (NCI)

C62153 VRMIN Summary (Min) The minimum time between successive cycles of Minimum Ventricular Heart Rate Ventricular Rate contraction and subsequent relaxation of the ventricles, usually expressed as beats per minute, obtained from a set of measurements of the ventricular rate. (NCI)

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 57 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C99079 - EPOCH - Epoch Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C99158 FOLLOW-UP A period in a clinical study during which information Clinical Study Follow-up about the health status of an individual is obtained after study procedures and treatments have concluded.

C98779 RUN-IN A period in a clinical study that occurs before the Run-in Period commencement of the primary clinical study investigation, during which subjects may be assessed for suitability in the clinical study, withdrawn from existing therapy, trained in study methodology or evaluated for any other protocol-specified reason.

C48262 SCREENING A period in a clinical study during which subjects are Trial Screening evaluated for participation in the study.

C49236 TREATMENT A period in a clinical study during which subjects Therapeutic Procedure receive therapeutic treatment.

C42872 WASHOUT A period of time during a clinical study when a Washout Period participant is taken off of a study drug or other medication in order to eliminate the effects of the treatment.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 58 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C66790 - ETHNIC - Ethnic Group Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C17459 HISPANIC OR LATINO A person of Mexican, Puerto Rican, Cuban, Central or Hispanic or Latino South American or other Spanish culture or origin, regardless of race. (NCI)

C41222 NOT HISPANIC OR LATINO A person not of Cuban, Mexican, Puerto Rican, South Not Hispanic or Latino or Central American, or other Spanish culture or origin, regardless of race. An arbitrary ethnic classification. (NCI)

C43234 NOT REPORTED Not reported Not provided or available. Not Stated

C17998 UNKNOWN U; Unknown Not known, not observed, not recorded, or refused. Unknown (NCI)

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 59 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C78735 - EVAL - Evaluator Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C78726 ADJUDICATION An external committee whose purpose is to evaluate Adjudication Committee COMMITTEE study data and decide whether a study endpoint or other criterion has been met. (NCI)

C17445 CAREGIVER Caregiver The primary person in charge of the care of a patient, Caregiver usually a family member or a designated health care professional. (NCI)

C42708 CHILD A son or a daughter. Child

C25465 CLINICAL RESEARCH Research A person who is employed by a study sponsor or by a Clinical Research Associate ASSOCIATE Associate contract research organization (CRO), operates independently from the clinical study site and functions as a monitor, and/or auditor, and/or a project director within a particular trial or institution. (NCI)

C51811 CLINICAL RESEARCH A person to whom a clinical investigator delegates Clinical Coordinator COORDINATOR routine administrative requirements of a protocol. The duties and responsibilities of a clinical research coordinator may vary across different infrastructures. Generally, the coordinator manages the subject's clinical trial participation and provides a vital linkage between the subject, the investigator, and the sponsor. (NCI)

C70793 CLINICAL STUDY Clinical Study An entity that is responsible for the initiation, Clinical Study Sponsor SPONSOR Sponsor; Study management, and/or financing of a clinical study. Sponsor, Sponsor

C53262 DOMESTIC PARTNER Domestic A person who is a member of an unmarried couple, Domestic Partnership Partner including same sex couples living together in longstanding relationships, that are registered or unregistered. (NCI)

C72884 FRIEND A person whom an individual knows, likes, and trusts. Friend (NCI)

C51828 GUARDIAN An individual who is authorized under applicable State Guardian or local law to consent on behalf of a child or incapable person to general medical care including participation in clinical research. (NCI)

C53287 HEALTH CARE A person qualified to be engaged in activity directed at Health Care Professional PROFESSIONAL preservation of mental and physical health by diseases prevention and treatment as a source of livelihood. (NCI)

C78720 INDEPENDENT ASSESSOR An individual qualified to perform an evaluation who is Independent Rater masked from a subject's data in order to minimize bias or maximize consistency and quality. (NCI)

C25936 INVESTIGATOR A person responsible for the conduct of the clinical Investigator trial at a trial site. If a trial is conducted by a team of individuals at the trial site, the investigator is the responsible leader of the team and may be called the principle investigator.

C42709 PARENT A mother or a father. Parent

C62649 SPOUSE Spouse A person's partner in marriage. (NCI) Spouse

C41189 STUDY SUBJECT An individual who is observed, analyzed, examined, Study Subject investigated, experimented upon, or/and treated in the course of a particular study.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 60 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C71113 - FREQ - Frequency Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C64526 1 TIME PER WEEK One Time Per One time per week. (NCI) Once Weekly Week

C98861 2 TIMES PER YEAR 2 Times Per Year Two times per year. (NCI) Two Times Yearly

C98859 3 TIMES PER MONTH 3 Times Per Three times per month. (NCI) Three Times Monthly Month

C98860 3 TIMES PER YEAR 3 Times Per Year Three times per year. (NCI) Three Times Yearly

C98852 4 TIMES PER MONTH 4 Times Per Four times per month. (NCI) Four Times Monthly Month

C98853 4 TIMES PER YEAR 4 Times Per Year Four times per year. (NCI) Four Times Yearly

C98849 5 TIMES PER DAY 5 Times Daily Five times per day. (NCI) Five Times Daily

C98850 5 TIMES PER MONTH 5 Times Per Five times per month. (NCI) Five Times Monthly Month

C85552 5 TIMES PER WEEK 5 Times Per Five times per week. (NCI) Five Times Weekly Week

C98851 5 TIMES PER YEAR 5 Times Per Year Five times per year. (NCI) Five Times Yearly

C98855 6 TIMES PER DAY 6 Times Daily Six times per day. (NCI) Six Times Daily

C98856 6 TIMES PER MONTH 6 Times Per Six times per month. (NCI) Six Times Monthly Month

C98857 6 TIMES PER WEEK 6 Times Per Six times per week. (NCI) Six Times Weekly Week

C98858 6 TIMES PER YEAR 6 Times Per Year Six times per year. (NCI) Six Times Yearly

C98854 7 TIMES PER WEEK 7 Times Per Seven times per week. (NCI) Seven Times Weekly Week

C64636 AD LIBITUM Ad Libitum As much as desired. As Much as Desired

C64496 BID BD; Twice per Two times per day, at unspecified times. (NCI) Twice Daily day

C71129 BIM Twice per month Twice per month. (NCI) Twice Per Month

C64497 BIS Twice per week Two times per week. (NCI) Twice Weekly

C53279 CONTINUOUS Continuous Remain in force or carry on without letup; keep or Continue maintain in unaltered condition; exist in time or space without stop or interruption. (NCI)

C71325 INTERMITTENT Intermittent Periodically stopping and starting. (NCI) Intermittent

C64954 OCCASIONAL Occasional Not occurring regularly or at short intervals. Infrequent

C64576 ONCE Once A one time intervention. (NCI) Once

C17649 OTHER Other Different than the one(s) previously specified or Other mentioned. (NCI)

C74924 PA Per Annum; Per A frequency rate of occurrences of something within a Per Year Year period of time equal to three hundred sixty-five days.

C64499 PRN As needed As needed. (NCI) As Necessary

C64500 Q10H Every 10 hours Every ten hours. (NCI) Every Ten Hours

C64501 Q11H Every 11 hours Every eleven hours. (NCI) Every Eleven Hours

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 61 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C71113 - FREQ - Frequency Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C64502 Q12H Every 12 hours Every twelve hours. (NCI) Every Twelve Hours

C64503 Q13H Every 13 hours Every thirteen hours. (NCI) Every Thirteen Hours

C64504 Q14H Every 14 hours Every fourteen hours. (NCI) Every Fourteen Hours

C64505 Q15H Every 15 hours Every fifteen hours. (NCI) Every Fifteen Hours

C64506 Q16H Every 16 hours Every sixteen hours. (NCI) Every Sixteen Hours

C64507 Q17H Every 17 hours Every seventeen hours. (NCI) Every Seventeen Hours

C64508 Q18H Every 18 hours Every eighteen hours. (NCI) Every Eighteen Hours

C64509 Q19H Every 19 hours Every nineteen hours. (NCI) Every Nineteen Hours

C64511 Q20H Every 20 hours Every twenty hours. (NCI) Every Twenty Hours

C64512 Q21H Every 21 hours Every twenty-one hours. (NCI) Every Twenty-One Hours

C64513 Q22H Every 22 hours Every twenty-two hours. (NCI) Every Twenty-Two Hours

C64514 Q23H Every 23 hours Every twenty-three hours. (NCI) Every Twenty-Three Hours

C64515 Q24H Every 24 hours Every twenty-four hours. (NCI) Every Twenty-Four Hours

C64516 Q2H Every 2 hours Every two hours. (NCI) Every Two Hours

C64536 Q2M Every two Every two months. (NCI) Every Two Months months

C71127 Q2S Every 2 weeks Every two weeks. (NCI) Every Two Weeks

C64533 Q3D Every 3 days Every three days. (NCI) Every Three Days

C64517 Q3H Every 3 hours Every three hours. (NCI) Every Three Hours

C64537 Q3M Every 3 months Every three months. (NCI) Every Three Months

C64535 Q3S Every 3 weeks Every three weeks. (NCI) Every Three Weeks

C64534 Q4D Every 4 days Every four days. (NCI) Every Four Days

C64518 Q4H Every 4 hours Every four hours. (NCI) Every Four Hours

C64538 Q4M Every 4 months Every four months. (NCI) Every Four Months

C64529 Q4S Every 4 weeks Every four weeks. (NCI) Every Four Weeks

C71124 Q5D Every 5 days Every five days. (NCI) Every Five Days

C64519 Q5H Every 5 hours Every five hours. (NCI) Every Five Hours

C64520 Q6H Every 6 hours Every six hours. (NCI) Every Six Hours

C89788 Q6S Every 6 Weeks Every six weeks. (NCI) Every Six Weeks

C64521 Q7H Every 7 hours Every seven hours. (NCI) Every Seven Hours

C64523 Q8H Every 8 hours Every eight hours. (NCI) Every Eight Hours

C64524 Q9H Every 9 hours Every nine hours. (NCI) Every Nine Hours

C25473 QD Daily Occurring or done each day. Daily

C64510 QH Every hour Every hour. (NCI) Every Hour

C64530 QID 4 times per day Four times per day. (NCI) Four Times Daily

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 62 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C71113 - FREQ - Frequency Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C64531 QIS 4 times per week Four times per week. (NCI) Four Times Weekly

C64498 QM Every Month Every month. (NCI) Monthly

C64525 QOD Every other day Every other day. (NCI) Every Other Day

C67069 QS Every week; Per Every week. (NCI) Weekly Week

C64527 TID 3 times per day Three times per day. (NCI) Three Times Daily

C64528 TIS Three times a Three times per week. (NCI) Three Times Weekly week

C17998 UNKNOWN U; Unknown Not known, not observed, not recorded, or refused. Unknown (NCI)

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 63 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C66726 - FRM - Pharmaceutical Dosage Form Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C42887 AEROSOL aer A product that is packaged under pressure and contains Aerosol Dosage Form therapeutically active ingredients that are released upon activation of an appropriate valve system; it is intended for topical application to the skin as well as local application into the nose (nasal aerosols), mouth (lingual aerosols), or lungs (inhalation aerosols). (FDA)

C42888 AEROSOL, FOAM A dosage form containing one or more active Aerosol Foam Dosage Form ingredients, surfactants, aqueous or non-aqueous liquids, and the propellants; if the propellant is in the internal (discontinuous) phase (i.e., of the oil-in-water type), a stable foam is discharged, and if the propellant is in the external (continuous) phase (i.e., of the water-in-oil type), a spray or a quick-breaking foam is discharged. (FDA)

C42960 AEROSOL, METERED A pressurized dosage form consisting of metered dose Metered Aerosol Dosage Form valves which allow for the delivery of a uniform quantity of spray upon each activation. (NCI)

C42971 AEROSOL, POWDER A product that is packaged under pressure and contains Powder Aerosol Dosage Form therapeutically active ingredients, in the form of a powder, that are released upon activation of an appropriate valve system. (NCI)

C42889 AEROSOL, SPRAY An aerosol product which utilizes a compressed gas as Aerosol Spray Dosage Form the propellant to provide the force necessary to expel the product as a wet spray; it is applicable to solutions of medicinal agents in aqueous solvents. (NCI)

C42892 BAR, CHEWABLE A solid dosage form usually in the form of a rectangle Chewable Bar Dosage Form that is meant to be chewed. (NCI)

C42890 BEAD A solid dosage form in the shape of a small ball. (NCI) Bead Dosage Form

C43451 BEAD, IMPLANT, A small sterile solid mass consisting of a highly Extended Release Bead Implant EXTENDED RELEASE purified drug intended for implantation in the body Dosage Form which would allow at least a reduction in dosing frequency as compared to that drug presented as a conventional dosage form. (NCI)

C42891 BLOCK Solid dosage form, usually in the shape of a square or Block Dosage Form rectangle. (NCI)

C97197 CAPLET A solid dosage form in which a tablet has been Caplet Dosage Form compacted into capsule shape.

C25158 CAPSULE cap A solid pharmaceutical dosage form that contains Capsule Dosage Form medicinal agent within either a hard or soft soluble container or shell, usually used for the oral administration of medicine. The shells are made of a suitable form of gelatin or other substance. (NCI)

C42895 CAPSULE, COATED A solid dosage form in which the drug is enclosed Coated Capsule Dosage Form within either a hard or soft soluble container or "shell" made from a suitable form of gelatin; additionally, the capsule is covered in a designated coating. (NCI)

C42896 CAPSULE, COATED A solid dosage form in which the drug is enclosed Coated Pellets in Capsule Dosage PELLETS within either a hard or soft soluble container or "shell" Form made from a suitable form of gelatin; the drug itself is in the form of granules to which varying amounts of coating have been applied. (NCI)

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 64 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C66726 - FRM - Pharmaceutical Dosage Form Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C42917 CAPSULE, COATED, A solid dosage form in which the drug is enclosed Extended Release Coated Capsule EXTENDED RELEASE within either a hard or soft soluble container or "shell" Dosage Form made from a suitable form of gelatin; additionally, the capsule is covered in a designated coating, and which releases a drug (or drugs) in such a manner to allow at least a reduction in dosing frequency as compared to that drug (or drugs) presented as a conventional dosage form. (NCI)

C42902 CAPSULE, DELAYED A solid dosage form in which the drug is enclosed Delayed Release Capsule Dosage RELEASE within either a hard or soft soluble container made Form from a suitable form of gelatin, and which releases a drug (or drugs) at a time other than promptly after administration. Enteric-coated articles are delayed release dosage forms. (NCI)

C42904 CAPSULE, DELAYED A solid dosage form in which the drug is enclosed Delayed Release Pellets in Capsule RELEASE PELLETS within either a hard or soft soluble container or "shell" Dosage Form made from a suitable form of gelatin; the drug itself is in the form of granules to which enteric coating has been applied, thus delaying release of the drug until its passage into the intestines. (NCI)

C42916 CAPSULE, EXTENDED A solid dosage form in which the drug is enclosed Extended Release Capsule Dosage RELEASE within either a hard or soft soluble container made Form from a suitable form of gelatin, and which releases a drug (or drugs) in such a manner to allow a reduction in dosing frequency as compared to that drug (or drugs) presented as a conventional dosage form. (NCI)

C42928 CAPSULE, FILM COATED, A solid dosage form in which the drug is enclosed Extended Release Film Coated EXTENDED RELEASE within either a hard or soft soluble container or "shell" Capsule Dosage Form made from a suitable form of gelatin; additionally, the capsule is covered in a designated film coating, and which releases a drug (or drugs) in such a manner to allow at least a reduction in dosing frequency as compared to that drug (or drugs) presented as a conventional dosage form. (NCI)

C42936 CAPSULE, GELATIN A solid dosage form in which the drug is enclosed Gelatin Coated Capsule Dosage COATED within either a hard or soft soluble container made Form from a suitable form of gelatin; through a banding process, the capsule is coated with additional layers of gelatin so as to form a complete seal. (NCI)

C42954 CAPSULE, LIQUID FILLED A solid dosage form in which the drug is enclosed Liquid Filled Capsule Dosage Form within a soluble, gelatin shell which is plasticized by the addition of a polyol, such as sorbitol or glycerin, and is therefore of a somewhat thicker consistency than that of a hard shell capsule; typically, the active ingredients are dissolved or suspended in a liquid vehicle. (NCI)

C45414 CEMENT A substance that serves to produce solid union between Cement Dosage Form two surfaces. (NCI)

C42678 CIGARETTE A narrow tube filled with material that is capable to Cigarette Dosage Form burn with release of therapeutically-active substance(s) during the process of smoking. Cigarette is a very efficient drug-delivery inhaler system for fast-acting substances.(FDA)

C60884 CLOTH A large piece of relatively flat, absorbent material that Cloth Dosage Form contains a drug. It is typically used for applying medication or for cleansing. (FDA)

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 65 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C66726 - FRM - Pharmaceutical Dosage Form Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C60891 CONCENTRATE A liquid preparation of increased strength and reduced Concentrate Dosage Form volume which is usually diluted prior to administration. (NCI)

C42900 CONE A solid dosage form bounded by a circular base and the Cone Dosage Form surface formed by line segments joining every point of the boundary of the base to a common vertex. A cone (usually containing antibiotics) is normally placed below the gingiva after a dental extraction. (NCI)

C42919 CORE, EXTENDED An ocular system placed in the eye from which the Extended Release Core Dosage RELEASE drug diffuses through a membrane at a constant rate Form over a specified period. (NCI)

C28944 CREAM A semisolid emulsion of either the oil-in-water or the Cream Dosage Form water-in-oil type, ordinarily intended for topical use. (NCI)

C60897 CREAM, AUGMENTED A cream dosage form that enhances drug delivery. Augmented Cream Dosage Form Augmentation does not refer to the strength of the drug in the dosage form. NOTE: CDER has decided to refrain from expanding the use of this dosage form due to difficulties in setting specific criteria that must be met to be considered augmented. (FDA)

C42901 CRYSTAL A naturally produced angular solid of definite form in Crystal Dosage Form which the ultimate units from which it is built up are systematically arranged; they are usually evenly spaced on a regular space lattice.

C45415 CULTURE The propagation of microorganisms or of living tissue Culture Dosage Form cells in special media conducive to their growth. (NCI)

C47890 DIAPHRAGM A device usually dome-shaped, worn during copulation Diaphragm Dosage Form over the cervical mouth for prevention of conception or infection. (NCI)

C43525 DISC A circular plate-like organ or structure. (FDA) Disc Dosage Form

C42679 DOUCHE A liquid preparation, intended for the irrigative Douche Dosage Form cleansing of the vagina, that is prepared from powders, liquid solutions, or liquid concentrates and contains one or more chemical substances dissolved in a suitable solvent or mutually miscible solvents. (NCI)

C42763 DRESSING The application of various materials for protecting a Dressing Dosage Form wound.(FDA)

C17423 DRUG DELIVERY SYSTEM Modern technology, distributed with or as a part of a Drug Delivery System drug product that allows for the uniform release or targeting of drugs to the body. (FDA)

C42912 ELIXIR A clear, pleasantly flavored, sweetened hydroalcoholic Elixir Dosage Form liquid containing dissolved medicinal agents; it is intended for oral use. (NCI)

C42913 EMULSION A dosage form consisting of a two-phase system Emulsion Dosage Form comprised of at least two immiscible liquids (1), one of which is dispersed as droplets (internal or dispersed phase) within the other liquid (external or continuous phase), generally stabilized with one or more emulsifying agents. Note 1: A liquid is pourable; it flows and conforms to its container at room temperature. It displays Newtonian or pseudoplastic flow behavior. Note 2: Emulsion is used as a dosage form term unless a more specific term is applicable, e.g. cream, lotion, ointment. (NCI)

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 66 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C66726 - FRM - Pharmaceutical Dosage Form Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C42915 ENEMA A rectal preparation for therapeutic, diagnostic, or Enema Dosage Form nutritive purposes. (NCI)

C42929 EXTRACT A concentrated preparation of vegetable or animal Extract Dosage Form drugs obtained by removal of the active constituents of the respective drugs with a suitable menstrua, evaporation of all or nearly all of the solvent, and adjustment of the residual masses or powders to the prescribed standards. (NCI)

C60926 FIBER, EXTENDED A slender and elongated solid thread-like substance Extended Release Fiber Dosage RELEASE that delivers drug in such a manner to allow a reduction Form in dosing frequency as compared to that drug (or drugs) presented as a conventional dosage form. (FDA)

C42932 FILM A thin layer or coating. (NCI) Film Dosage Form

C42920 FILM, EXTENDED RELEASE A drug delivery system in the form of a film that Extended Release Film Dosage Form releases the drug over an extended period in such a way as to maintain constant drug levels in the blood or target tissue. (NCI)

C42984 FILM, SOLUBLE A thin layer or coating which is susceptible to being Soluble Film Dosage Form dissolved when in contact with a liquid. (NCI)

C60927 FOR SOLUTION A product, usually a solid, intended for solution prior Dosage Form For Solution to administration. (FDA)

C60928 FOR SUSPENSION A product, usually a solid, intended for suspension Dosage Form For Suspension prior to administration. (FDA)

C60929 FOR SUSPENSION, A product, usually a solid, intended for suspension Extended Release Dosage Form For EXTENDED RELEASE prior to administration; once the suspension is Suspension administered, the drug will be released at a constant rate over a specified period. (FDA)

C42933 GAS Any elastic aeriform fluid in which the molecules are Gas Dosage Form separated from one another and have free paths. (NCI)

C42934 GEL A semisolid (1) dosage form that contains a gelling Gel Dosage Form agent to provide stiffness to a solution or a colloidal dispersion (2). A gel may contain suspended particles. Note 1: A semisolid is not pourable; it does not flow or conform to its container at room temperature. It does not flow at low shear stress and generally exhibits plastic flow behavior. Note 2: A colloidal dispersion is a system in which particles of colloidal dimension (i.e., typically between 1 nm and 1 micrometer) are distributed uniformly throughout a liquid. (NCI)

C42906 GEL, DENTIFRICE A combination of a dentifrice (formulation intended to Dentifrice Gel Dosage Form clean and/or polish the teeth, and which may contain certain additional agents), and a gel. It is used with a toothbrush for the purpose of cleaning and polishing the teeth. (NCI)

C60930 GEL, METERED A gel preparation, with metered dose valves, which Metered Gel Dosage Form allow for the delivery of a uniform quantity of gel upon each activation. (FDA)

C48193 GENERATOR An apparatus for the formation of vapor or gas from a Generator Dosage Form liquid or solid by heat or chemical action. The term GENERATOR also applies to radioactive columns from which radionuclides are provided. (NCI)

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 67 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C66726 - FRM - Pharmaceutical Dosage Form Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C42937 GLOBULE Also called pellets or pilules, are made of pure Globule Dosage Form sucrose, lactose, or other polysaccharides. They are formed into small globular masses of various sizes, and are medicated by placing them in a vial and adding the liquid drug attenuation in the proportion not less than one percent (v/w). After shaking, the medicated globules are dried at temperatures not to exceed 40 degrees Centigrade. (NCI)

C45416 GRAFT A slip of skin or of other tissue for implantation. Graft Dosage Form (NCI)

C42938 GRANULE A small particle or grain. (NCI) Granule Dosage Form

C42903 GRANULE, DELAYED A small medicinal particle or grain to which an enteric Delayed Release Granule Dosage RELEASE or other coating has been applied, thus delaying release Form of the drug until its passage into the intestines. (NCI)

C42909 GRANULE, EFFERVESCENT A small particle or grain containing a medicinal agent Effervescent Granule Dosage Form in a dry mixture usually composed of sodium bicarbonate, citric acid, and tartaric acid which, when in contact with water, has the capability to release gas, resulting in effervescence. (NCI)

C42939 GRANULE, FOR SOLUTION A small medicinal particle or grain made available in Granule For Solution Dosage Form its more stable dry form, to be reconstituted with solvent just before dispensing; the granules are so prepared to contain not only the medicinal agent, but the colorants, flavorants, and any other desired pharmaceutic ingredient. (NCI)

C42940 GRANULE, FOR A small medicinal particle or grain made available in Granule For Suspension Dosage SUSPENSION its more stable dry form, to be reconstituted with Form solvent just before dispensing to form a suspension; the granules are so prepared to contain not only the medicinal agent, but the colorants, flavorants, and any other desired pharmaceutic ingredient. (NCI)

C42921 GRANULE, FOR A small medicinal particle or grain made available in Extended Release Granule For SUSPENSION, EXTENDED its more stable dry form, to be reconstituted with Suspension Dosage Form RELEASE solvent just before dispensing to form a suspension; the extended release system achieves slow release of the drug over an extended period of time and maintains constant drug levels in the blood or target tissue. (NCI)

C42941 GUM A mucilaginous excretion from various plants. (NCI) Gum Dosage Form

C42894 GUM, CHEWING A sweetened and flavored insoluble plastic material of Chewing Gum Dosage Form various shapes which when chewed, releases a drug substance into the oral cavity. (NCI)

C42978 GUM, RESIN Natural mixture of gum and resin, usually obtained as Resin Gum Dosage Form exudations from plants. (NCI)

C42942 IMPLANT A material containing drug intended to be inserted Implant Dosage Form securely and deeply in a living site for growth, slow release, or formation of an organic union. (NCI)

C42944 INHALANT A special class of inhalations consisting of a drug or Inhalant Dosage Form combination of drugs, that by virtue of their high vapor pressure, can be carried by an air current into the nasal passage where they exert their effect; the container from which the inhalant generally is administered is known as an inhaler. (NCI)

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 68 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C66726 - FRM - Pharmaceutical Dosage Form Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C60931 INJECTABLE, LIPOSOMAL An injection, which either consists of or forms Liposomal Injection Dosage Form liposomes (a lipid bilayer vesicle usually composed of phospholipids which is used to encapsulate an active drug substance). (FDA)

C42946 INJECTION A sterile preparation intended for parenteral use; five Injectable Dosage Form distinct classes of injections exist as defined by the USP. (NCI)

C42914 INJECTION, EMULSION An emulsion consisting of a sterile, pyrogen-free Emulsion for Injection Dosage Form preparation intended to be administered parenterally.(FDA)

C42950 INJECTION, LIPID [definition pending](FDA) Injectable Lipid Complex Dosage COMPLEX Form

C42974 INJECTION, POWDER, FOR A sterile preparation intended for reconstitution to Powder For Injectable Solution SOLUTION form a solution for parenteral use. (NCI) Dosage Form

C42976 INJECTION, POWDER, FOR A sterile preparation intended for reconstitution to Powder For Injectable Suspension SUSPENSION form a suspension for parenteral use. (NCI) Dosage Form

C42977 INJECTION, POWDER, FOR A dried preparation intended for reconstitution to form Powder For Injectable Extended SUSPENSION, EXTENDED a suspension for parenteral use which has been Release Suspension Dosage Form RELEASE formulated in a manner to allow at least a reduction in dosing frequency as compared to that drug presented as a conventional dosage form (e.g., as a solution).(FDA)

C42959 INJECTION, POWDER, A sterile freeze dried preparation intended for Lyophilized Powder For Injectable LYOPHILIZED, FOR reconstitution for parenteral use which has been Liposomal Suspension Dosage Form LIPOSOMAL SUSPENSION formulated in a manner that would allow liposomes (a lipid bilayer vesicle usually composed of phospholipids which is used to encapsulate an active drug substance, either within a lipid bilayer or in an aqueous space) to be formed upon reconstitution. (NCI)

C42957 INJECTION, POWDER, A dosage form intended for the solution prepared by Lyophilized Powder For Injectable LYOPHILIZED, FOR lyophilization ('freeze drying'), a process which Solution Dosage Form SOLUTION involves the removal of water from products in the frozen state at extremely low pressures; this is intended for subsequent addition of liquid to create a solution that conforms in all respects to the requirements for Injections. (NCI)

C42958 INJECTION, POWDER, A liquid preparation, intended for parenteral use, that Lyophilized Powder For Injectable LYOPHILIZED, FOR contains solids suspended in a suitable fluid medium Suspension Dosage Form SUSPENSION and conforms in all respects to the requirements for Sterile Suspensions; the medicinal agents intended for the suspension are prepared by lyophilization ("freeze drying"), a process which involves the removal of water from products in the frozen state at extremely low pressures. (NCI)

C42956 INJECTION, POWDER, A sterile freeze dried preparation intended for Lyophilized Powder For Extended LYOPHILIZED, FOR reconstitution for parenteral use which has been Release Injectable Suspension SUSPENSION, EXTENDED formulated in a manner to allow at least a reduction in Dosage Form RELEASE dosing frequency as compared to that drug presented as a conventional dosage form (e.g., as a solution). (NCI)

C42945 INJECTION, SOLUTION A liquid preparation containing one or more drug Injectable Solution Dosage Form substances dissolved in a suitable solvent or mixture of mutually miscible solvents that is suitable for injection. (NCI)

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 69 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C66726 - FRM - Pharmaceutical Dosage Form Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C42899 INJECTION, SOLUTION, A sterile preparation for parenteral use which, upon the Concentrate for Injectable Solution CONCENTRATE addition of suitable solvents, yields a solution Dosage Form conforming in all respects to the requirements for Injections. (NCI)

C42995 INJECTION, SUSPENSION A liquid preparation, suitable for injection, which Injectable Suspension Dosage Form consists of solid particles dispersed throughout a liquid phase in which the particles are not soluble. It can also consist of an oil phase dispersed throughout an aqueous phase, or vice-versa. (NCI)

C42926 INJECTION, SUSPENSION, A sterile preparation intended for parenteral use which Injectable Extended Release EXTENDED RELEASE has been formulated in a manner to allow at least a Suspension Dosage Form reduction in dosing frequency as compared to that drug presented as a conventional dosage form (e.g., as a solution or a prompt drug-releasing, conventional solid dosage form). (NCI)

C42951 INJECTION, SUSPENSION, A liquid parenteral pharmaceutical dosage form Injectable Liposomal Suspension LIPOSOMAL structured as a multilamellar composition of Dosage Form concentric phospholipid spheres that encapsulate the drug (drug delivery systems) separated by layers of water. Drug release is facilitated and controlled by in vivo erosion of the liposomes. To further increase the in vivo circulation time, liposomes in some preparations are covalently derivatized with PEG to produce PEGylated or stealth liposomes. Covalent attachment of drugs to the outer surface of liposomes can potentially serve as a delayed-release product. (NCI)

C42988 INJECTION, SUSPENSION, A liquid preparation, suitable for injection, which Injectable Sonicated Suspension SONICATED consists of solid particles dispersed throughout a Dosage Form liquid phase in which the particles are not soluble. In addition, the product is sonicated while a gas is bubbled through the suspension, and this results in the formation of microspheres by the solid particles. (NCI)

C60933 INSERT A specially formulated and shaped non-encapsulated Insert Dosage Form solid preparation intended to be placed into a non-rectal orifice of the body, where drug is released, generally for localized effects. (FDA)

C42922 INSERT, EXTENDED A specially formulated and shaped solid preparation Extended Release Insert Dosage RELEASE (e.g., ring, tablet, or stick) intended to be placed in the Form vagina by special inserters, where the medication is released, generally for localized effects; the extended release preparation is designed to allow a reduction in dosing frequency. (NCI)

C47915 INTRAUTERINE DEVICE A device inserted and left in the uterus to prevent Intrauterine Device Dosage Form effective conception. (NCI)

C42947 IRRIGANT A sterile solution intended to bathe or flush open Irrigant Dosage Form wounds or body cavities; they're used topically, never parenterally. (NCI)

C42948 JELLY A class of gels--semisolid systems which consist of Jelly Dosage Form suspensions made up of either small inorganic particles or large organic molecules interpenetrated by a liquid--in which the structural coherent matrix contains a high portion of liquid, usually water. (NCI)

C47916 KIT A packaged collection of related material. (NCI) Kit Dosage Form

C45413 LINER, DENTAL A material applied to the inside of the dental cavity, for Dental Liner Dosage Form protection or insulation of the surface.(FDA)

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 70 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C66726 - FRM - Pharmaceutical Dosage Form Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C42949 LINIMENT A solution or mixture of various substances in oil, Liniment Dosage Form alcoholic solutions of soap, or emulsions intended for external application. (NCI)

C42952 LIPSTICK A waxy solid, usually colored cosmetic, in stick form Lipstick Dosage Form for the lips. (NCI)

C42953 LIQUID A dosage form consisting of a pure chemical in its Liquid Dosage Form liquid state. This dosage form term should not be applied to solutions. Note: A liquid is pourable; it flows and conforms to its container at room temperature. It displays Newtonian or pseudoplastic flow behavior.(FDA)

C60934 LIQUID, EXTENDED A liquid that delivers a drug in such a manner to allow a Extended Release Liquid Dosage RELEASE reduction in dosing frequency as compared to that drug Form (or drugs) presented as a conventional dosage form. (FDA)

C29167 LOTION An emulsion, liquid (1) dosage form. This dosage form Lotion Dosage Form is generally for external application to the skin (2). Note 1: A liquid is pourable; it flows and conforms to its container at room temperature. It displays Newtonian or pseudoplastic flow behavior. Note 2: Previously the definition of a lotion was: The term lotion has been used to categorize many topical suspensions, solutions, and emulsions intended for application to the skin. The current definition of a lotion is restricted to an emulsion. (FDA)

C60957 LOTION, AUGMENTED A lotion dosage form that enhances drug delivery. Augmented Lotion Dosage Form Augmentation does not refer to the strength of the drug in the dosage form. NOTE: CDER has decided to refrain from expanding the use of this dosage form due to difficulties in setting specific criteria that must be met to be considered augmented. (FDA)

C60958 LOTION/SHAMPOO A lotion dosage form which has a soap or detergent Lotion Shampoo Dosage Form that is usually used to clean the hair and scalp; it is often used as a vehicle for dermatologic agents. (FDA)

C42955 LOZENGE A solid preparation containing one or more Lozenge Dosage Form medicaments, usually in a flavored, sweetened base which is intended to dissolve or disintegrate slowly in the mouth. A lollipop is a lozenge on a stick.(FDA)

C29269 MOUTHWASH An aqueous solution which is most often used for its Mouthwash Dosage Form deodorant, refreshing, or antiseptic effect. (NCI)

C48624 NOT APPLICABLE The use of a dosage form term is not relevant or Dosage Form Not Applicable appropriate. (NCI)

C42965 OIL An unctuous, combustible substance which is liquid, or Oil Dosage Form easily liquefiable, on warming, and is soluble in ether but insoluble in water. Such substances, depending on their origin, are classified as animal, mineral, or vegetable oils. (NCI)

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 71 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C66726 - FRM - Pharmaceutical Dosage Form Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C42966 OINTMENT oint A suspension or emulsion, semisolid (1) dosage form, Ointment Dosage Form usually containing < 20% water and volatiles (2) and > 50% hydrocarbons, waxes, or polyols as the vehicle. This dosage form is generally for external application to the skin or mucous membranes. Note 1: A semisolid is not pourable; it does not flow or conform to its container at room temperature. It does not flow at low shear stress and generally exhibits plastic flow behavior. Note 2: Percent water and volatiles are measured by a loss on drying test in which the sample is heated at 105 degrees C until constant weight is achieved. (NCI)

C60984 OINTMENT, AUGMENTED An ointment dosage form that enhances drug delivery. Augmented Ointment Dosage Form Augmentation does not refer to the strength of the drug in the dosage form. NOTE: CDER has decided to refrain from expanding the use of this dosage form due to difficulties in setting specific criteria that must be met to be considered augmented. (FDA)

C47887 PACKING A material, usually covered by or impregnated with a Packing Dosage Form drug, that is inserted into a body cavity or between the tooth enamel and the gingival margin.(FDA)

C42967 PASTE A semisolid dosage form, containing a large Paste Dosage Form proportion (20 - 50%) of solids finely dispersed in a fatty vehicle. This dosage form is generally for external application to the skin or mucous membranes. Note: A semisolid is not pourable; it does not flow or conform to its container at room temperature. It does not flow at low shear stress and generally exhibits plastic flow behavior. (NCI)

C42907 PASTE, DENTIFRICE A paste formulation intended to clean and/or polish the Dentifrice Paste Dosage Form teeth, and which may contain certain additional agents. (NCI)

C60985 PASTILLE An aromatic preparation, often with a pleasing flavor, Pastille Dosage Form usually intended to dissolve in the mouth. (FDA)

C42968 PATCH A drug delivery system that often contains an adhesive Patch Dosage Form backing that is usually applied to an external site on the body. Its ingredients either passively diffuse from, or are actively transported from, some portion of the patch. Depending upon the patch, the ingredients are either delivered to the outer surface of the body or into the body. A patch is sometimes synonymous with the terms Extended Release Film and System. (NCI)

C42923 PATCH, EXTENDED A drug delivery system in the form of a patch that Extended Release Patch Dosage RELEASE releases the drug in such a manner that a reduction in Form dosing frequency compared to that drug presented as a conventional dosage form (e.g., a solution or a prompt drug-releasing, conventional solid dosage form). (NCI)

C42911 PATCH, EXTENDED A drug delivery system in the form of a patch which is Electrically Controlled Extended RELEASE, ELECTRICALLY controlled by an electric current that releases the drug Release Patch Dosage Form CONTROLLED in such a manner that a reduction in dosing frequency compared to that drug presented as a conventional dosage form (e.g., a solution or a prompt drug-releasing, conventional solid dosage form). (NCI)

C42969 PELLET A small sterile solid mass consisting of a highly Pellet Dosage Form purified drug (with or without excipients) made by the formation of granules, or by compression and molding. (NCI)

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 72 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C66726 - FRM - Pharmaceutical Dosage Form Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C42943 PELLET, IMPLANTABLE A small sterile solid mass consisting of a highly Implantable Pellet Dosage Form purified drug (with or without excipients) made by the formation of granules, or by compression and molding; they are intended for implantation in the body (usually subcutaneously) for the purpose of providing continuous release of the drug over long periods of time. (NCI)

C42918 PELLETS, COATED, A solid dosage form in which the drug itself is in the Extended Release Coated Pellets EXTENDED RELEASE form of granules to which varying amounts of coating Dosage Form have been applied, and which releases a drug (or drugs) in such a manner to allow a reduction in dosing frequency as compared to that drug (or drugs) presented as a conventional dosage form. (NCI)

C25394 PILL A dose of medicine in the form of a small pellet. Pill Dosage Form (NCI)

C42970 PLASTER Substance intended for external application made of Plaster Dosage Form such materials and of such consistency as to adhere to the skin and attach to a dressing; plasters are intended to afford protection and support and/or to furnish an occlusion and macerating action and to bring medication into close contact with the skin. (NCI)

C47913 POULTICE A soft, moist mass of meal, herbs, seed, etc., usually Poultice Dosage Form applied hot in cloth that consists of gruel-like consistency. (NCI)

C42972 POWDER An intimate mixture of dry, finely divided drugs and/or Powder Dosage Form chemicals that may be intended for internal or external use. (NCI)

C42908 POWDER, DENTIFRICE A powder formulation intended to clean and/or polish Dentifrice Powder Dosage Form the teeth, and which may contain certain additional agents. (NCI)

C42973 POWDER, FOR SOLUTION An intimate mixture of dry, finely divided drugs and/or Powder for Solution Dosage Form chemicals, which, upon the addition of suitable vehicles, yields a solution. (NCI)

C42975 POWDER, FOR An intimate mixture of dry, finely divided drugs and/or Powder for Suspension Dosage Form SUSPENSION chemicals, which, upon the addition of suitable vehicles, yields a suspension (a liquid preparation containing the solid particles dispersed in the liquid vehicle). (NCI)

C42961 POWDER, METERED A powder dosage form that is situated inside a Metered Powder Dosage Form container that has a mechanism to deliver a specified quantity. (NCI)

C60988 RING A small circular object with a vacant circular center Ring Dosage Form that is usually intended to be placed in the body by special inserters, where the medication is released, generally for localized effects. (FDA)

C42979 RINSE A liquid used to cleanse by flushing. (NCI) Rinse Dosage Form

C42980 SALVE A thick ointment or cerate (a fat or wax based Salve Dosage Form preparation with a consistency between an ointment and a plaster). (NCI)

C42981 SHAMPOO A liquid soap or detergent used to clean the hair and Shampoo Dosage Form scalp and is often used as a vehicle for dermatologic agents. (NCI)

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 73 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C66726 - FRM - Pharmaceutical Dosage Form Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C42982 SHAMPOO, SUSPENSION A liquid soap or detergent containing one or more Shampoo Suspension Dosage Form solid, insoluble substances dispersed in a liquid vehicle that is used to clean the hair and scalp and is often used as a vehicle for dermatologic agents. (NCI)

C42983 SOAP Any compound of one or more fatty acids, or their Soap Dosage Form equivalents, with an alkali; soap is detergent and is much employed in liniments, enemas, and in making pills. It is also a mild aperient, antacid and antiseptic. (NCI)

C42986 SOLUTION A clear, homogeneous liquid dosage form that contains Solution Dosage Form one or more chemical substances dissolved in a solvent or mixture of mutually miscible solvents. Note: A liquid is pourable; it flows and conforms to its container at room temperature. It displays Newtonian or pseudoplastic flow behavior. (NCI)

C42898 SOLUTION, CONCENTRATE A liquid preparation (i.e., a substance that flows readily Concentrate for Solution Dosage in its natural state) that contains a drug dissolved in a Form suitable solvent or mixture of mutually miscible solvents; the drug has been strengthened by the evaporation of its non-active parts. (NCI)

C42987 SOLUTION, FOR SLUSH A solution for the preparation of an iced saline slush, Solution For Slush Dosage Form which is administered by irrigation and used to induce regional hypothermia (in conditions such as certain open heart and kidney surgical procedures) by its direct application. (NCI)

C60994 SOLUTION, GEL A solution, which after usually being administered in a Gel Forming Drops Solution Dosage FORMING / DROPS drop-wise fashion, forms a gel. (FDA) Form

C42935 SOLUTION, GEL FORMING, A solution that forms a gel when it comes in contact Extended Release Gel Forming EXTENDED RELEASE with ocular fluid, and which allows at least a reduction Solution Dosage Form in dosing frequency. (FDA)

C60992 SOLUTION/ DROPS A solution which is usually administered in a Drops Solution Dosage Form drop-wise fashion. (FDA)

C47912 SPONGE A porous, interlacing, absorbent material that contains Sponge Dosage Form a drug. It is typically used for applying or introducing medication, or for cleansing. A sponge usually retains its shape.(FDA)

C42989 SPRAY A liquid minutely divided as by a jet of air or steam. Spray Dosage Form (NCI)

C42962 SPRAY, METERED A non-pressurized dosage form consisting of valves Metered Spray Dosage Form which allow the dispensing of a specified quantity of spray upon each activation. (NCI)

C42990 SPRAY, SUSPENSION A liquid preparation containing solid particles Spray Suspension Dosage Form dispersed in a liquid vehicle and in the form of coarse droplets or as finely divided solids to be applied locally, most usually to the nasal-pharyngeal tract, or topically to the skin. (NCI)

C42991 STICK A dosage form prepared in a relatively long and slender Stick Dosage Form often cylindrical form. (NCI)

C47914 STRIP A long narrow piece of material. Strip Dosage Form

C42993 SUPPOSITORY supp A solid body of various weights and shapes, adapted for Suppository Dosage Form introduction into the rectal, vaginal, or urethral orifice of the human body; they usually melt, soften, or dissolve at body temperature. (NCI)

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 74 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C66726 - FRM - Pharmaceutical Dosage Form Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C42924 SUPPOSITORY, EXTENDED A drug delivery system in the form of a suppository Extended Release Suppository RELEASE that allows at least a reduction in dosing frequency. Dosage Form (NCI)

C42994 SUSPENSION susp A liquid dosage form that contains solid particles Suspension Dosage Form dispersed in a liquid vehicle. Note: A liquid is pourable; it flows and conforms to its container at room temperature. It displays Newtonian or pseudoplastic flow behavior.(FDA)

C42925 SUSPENSION, EXTENDED A liquid preparation consisting of solid particles Extended Release Suspension RELEASE dispersed throughout a liquid phase in which the Dosage Form particles are not soluble; the suspension has been formulated in a manner to allow at least a reduction in dosing frequency as compared to that drug presented as a conventional dosage form (e.g., as a solution or a prompt drug-releasing, conventional solid dosage form). (NCI)

C60995 SUSPENSION/DROPS A suspension which is usually administered in a Drops Suspension Dosage Form dropwise fashion. (FDA)

C47889 SUTURE A strand or fiber used to hold wound edges in Suture Dosage Form apposition during healing. (NCI)

C47898 SWAB A small piece of relatively flat absorbent material that Swab Dosage Form contains a drug. A swab may also be attached to one end of a small stick. A swab is typically used for applying medication or for cleansing. (NCI)

C42996 SYRUP An oral solution containing high concentrations of Syrup Dosage Form sucrose or other sugars; the term has also been used to include any other liquid dosage form prepared in a sweet and viscid vehicle, including oral suspensions. (NCI)

C42998 TABLET tab A solid dosage form containing medicinal substances Tablet Dosage Form with or without suitable diluents. (NCI)

C42893 TABLET, CHEWABLE A solid dosage form containing medicinal substances Chewable Tablet Dosage Form with or without suitable diluents that is intended to be chewed, producing a pleasant tasting residue in the oral cavity that is easily swallowed and does not leave a bitter or unpleasant after-taste. (NCI)

C42897 TABLET, COATED A solid dosage form that contains medicinal Coated Tablet Dosage Form substances with or without suitable diluents and is covered with a designated coating. (NCI)

C60997 TABLET, COATED A solid dosage form containing a conglomerate of Tablet Coated Particles Dosage PARTICLES medicinal particles that have each been covered with a Form coating. (FDA)

C42905 TABLET, DELAYED A solid dosage form which releases a drug (or drugs) Delayed Release Tablet Dosage RELEASE at a time other than promptly after administration. Form Enteric-coated articles are delayed release dosage forms. (NCI)

C42997 TABLET, DELAYED A solid dosage form containing a conglomerate of Delayed Release Particles Tablet RELEASE PARTICLES medicinal particles that have been covered with a Dosage Form coating which releases a drug (or drugs) at a time other than promptly after administration. Enteric-coated articles are delayed release dosage forms. (NCI)

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 75 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C66726 - FRM - Pharmaceutical Dosage Form Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C42910 TABLET, EFFERVESCENT A solid dosage form containing mixtures of acids (e.g., Effervescent Tablet Dosage Form citric acid, tartaric acid) and sodium bicarbonate, which release carbon dioxide when dissolved in water; it is intended to be dissolved or dispersed in water before administration.(FDA)

C42927 TABLET, EXTENDED A solid dosage form containing a drug which allows at Extended Release Tablet Dosage RELEASE least a reduction in dosing frequency as compared to Form that drug presented in conventional dosage form. (NCI)

C42931 TABLET, FILM COATED A solid dosage form that contains medicinal Film Coated Tablet Dosage Form substances with or without suitable diluents and is coated with a thin layer of a water-insoluble or water-soluble polymer. (NCI)

C42930 TABLET, FILM COATED, A solid dosage form that contains medicinal Film Coated Extended Release EXTENDED RELEASE substances with or without suitable diluents and is Tablet Dosage Form coated with a thin layer of a water-insoluble or water-soluble polymer; the tablet is formulated in such manner as to make the contained medicament available over an extended period of time following ingestion. (NCI)

C61004 TABLET, FOR SOLUTION A tablet that forms a solution when placed in a liquid. Tablet For Solution Dosage Form (FDA)

C61005 TABLET, FOR SUSPENSION A tablet that forms a suspension when placed in a Tablet For Suspension Dosage Form liquid (formerly referred to as a Dispersible Tablet).

C42964 TABLET, MULTILAYER A solid dosage form containing medicinal substances Multilayered Tablet Dosage Form that have been compressed to form a multiple-layered tablet or a tablet-within-a-tablet, the inner tablet being the core and the outer portion being the shell. (NCI)

C42963 TABLET, MULTILAYER, A solid dosage form containing medicinal substances Multilayered Extended Release EXTENDED RELEASE that have been compressed to form a multiple-layered Tablet Dosage Form tablet or a tablet-within-a-tablet, the inner tablet being the core and the outer portion being the shell, which, additionally, is covered in a designated coating; the tablet is formulated in such manner as to allow at least a reduction in dosing frequency as compared to that drug presented as a conventional dosage form. (NCI)

C42999 TABLET, ORALLY A solid dosage form containing medicinal substances Orally Disintegrating Tablet Dosage DISINTEGRATING which disintegrates rapidly, usually within a matter of Form seconds, when placed upon the tongue. (NCI)

C61006 TABLET, ORALLY A solid dosage form containing medicinal substances Tablet Orally Disintegrating Delayed DISINTEGRATING, which disintegrates rapidly, usually within a matter of Release Dosage Form DELAYED RELEASE seconds, when placed upon the tongue, but which releases a drug (or drugs) at a time other than promptly after administration. (FDA)

C42985 TABLET, SOLUBLE A solid dosage form that contains medicinal Soluble Tablet Dosage Form substances with or without suitable diluents and possesses the ability to dissolve in fluids. (NCI)

C42992 TABLET, SUGAR COATED A solid dosage form that contains medicinal Sugar Coated Tablet Dosage Form substances with or without suitable diluents and is coated with a colored or an uncolored water-soluble sugar. (NCI)

C47892 TAMPON A plug made of cotton, sponge, or oakum variously Tampon Dosage Form used in surgery to plug the nose, vagina, etc., for the control of hemorrhage or the absorption of secretions. (NCI)

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 76 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C66726 - FRM - Pharmaceutical Dosage Form Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C47897 TAPE A narrow woven fabric, or a narrow extruded synthetic Tape Dosage Form (such as plastic), usually with an adhesive on one or both sides. (NCI)

C43000 TINCTURE An alcoholic or hydroalcoholic solution prepared from Tincture Dosage Form vegetable materials or from chemical substances. (NCI)

C43001 TROCHE A discoid-shaped solid containing the medicinal agent Troche Dosage Form in a suitably flavored base; troches are placed in the mouth where they slowly dissolve, liberating the active ingredients. (NCI)

C43002 UNASSIGNED A dosage form has yet to be assigned. (NCI) Unassigned Dosage Form

C43003 WAFER A thin slice of material containing a medicinal agent. Wafer Dosage Form (NCI)

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 77 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C66797 - IECAT - Category for Inclusion/Exclusion Codelist extensible: No

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C25370 EXCLUSION List of characteristics in a protocol, any one of which Exclusion Criteria may exclude a potential subject from participation in a study. (CDISC glossary)

C25532 INCLUSION The criteria in a protocol that prospective subjects Inclusion Criteria must meet to be eligible for participation in a study. NOTE: Exclusion and inclusion criteria define the study population. See also exclusion criteria. (CDISC glossary)

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 78 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C99076 - INTMODEL - Intervention Model Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C82637 CROSS-OVER Participants receive one of two or more alternative Crossover Study intervention(s) during the initial epoch of the study and receive other intervention(s) during the subsequent epoch(s) of the study.

C82638 FACTORIAL Two or more interventions, each alone and in Factorial Study combination, are evaluated in parallel against a control group.

C82639 PARALLEL Participants are assigned to one of two or more arms Parallel Study in parallel for the duration of the study.

C82640 SINGLE GROUP Single arm study. Single Group Study

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 79 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C99078 - INTTYPE - Intervention Type Codelist extensible: No

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C15184 BEHAVIORAL THERAPY A technique used to change subjects' behavior, for Behavioral Intervention example, psychotherapy, lifestyle counseling or hypnosis.

C307 BIOLOGIC A substance made from living organisms or things they Biological Agent produce, for example: virus, therapeutic serum, toxin, antitoxin, vaccine, blood, blood component or derivative, allergenic product, or analogous product.

C16830 DEVICE An instrument, apparatus, implement, machine, Medical Device contrivance, implant, in vitro reagent, or other similar or related article, including any component, part, or accessory, which is recognized in the official National Formulary, or the United States Pharmacopeia, or any supplement to them, intended for use in the diagnosis of disease or other conditions, or in the cure, mitigation, treatment, or prevention of disease, in man or other animals, or intended to affect the structure or any function of the body of man or other animals, and which does not achieve its primary intended purposes through chemical action within or on the body of man or other animals and which is not dependent upon being metabolized for the achievement of its primary intended purposes. (FDA)

C1505 DIETARY SUPPLEMENT Oral preparations containing dietary ingredient(s) Nutritional Supplement intended to supplement the diet. Dietary ingredients include vitamins, minerals, herbs, amino acids, extracts and metabolites.

C1909 DRUG An active natural, synthetic or semi-synthetic Pharmacologic Substance ingredient including endogenous body substance that is intended to furnish pharmacological activity or other direct effect in the diagnosis, cure, mitigation, treatment, or prevention of disease or to affect the structure or any function of the human body, but does not include intermediates used in the synthesis of such ingredient (21 CFR 314.3(b)).

C15238 GENETIC Application of genetic material into cells in order to Gene Therapy correct an inherited or acquired disease.

C17649 OTHER Different than the one(s) previously specified or Other mentioned. (NCI)

C98769 PROCEDURE A treatment procedure performed by manual and/or Physical Medical Procedure instrumental means, for example: surgery, lithotripsy, or external manipulation.

C15313 RADIATION Treatment of a disease by means of exposure of the Radiation Therapy target or the whole body to radiation.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 80 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C99073 - LAT - Laterality Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C13332 BILATERAL Affecting both sides of the body, or a pair of organs. Bilateral

C25307 CONTRALATERAL Having to do with the opposite side of the body, in Contralateral relation to a pre-existing reference point.

C25308 IPSILATERAL Having to do with the same side of the body, in relation Ipsilateral to a pre-existing reference point.

C25230 LATERAL Situated at or extending to the side. Lateral

C25229 LEFT Being or located on or directed toward the side of the Left body to the west when facing north.

C25228 RIGHT Being or located on or directed toward the side of the Right body to the east when facing north.

C28012 UNILATERAL Affecting one side of the body or one of a pair of Unilateral organs.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 81 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C67154 - LBTEST - Laboratory Test Name Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C92267 1, 25-Dihydroxyvitamin D 1, A measurement of the total active Vitamin D in a 1, 25-Dihydroxyvitamin D 25-Dihydroxyvit biological specimen. Measurement amin D; Active Vitamin D

C92268 25-Hydroxyvitamin D 25-Hydroxyvita A measurement of the total inactive Vitamin D in a 25-Hydroxyvitamin D Measurement min D; Inactive biological specimen. Vitamin D

C101017 3,4-Dihydroxyphenylglycol 3,4-Dihydroxyph A measurement of the catecholamine metabolite, 3,4-Dihydroxyphenylglycol enylglycol; 3.4 3,4-Dihydroxyphenylglycol in a biological specimen. Measurement Dihydroxyphenyl glycol

C79437 5 Prime Nucleotidase 5 Prime A measurement of the 5'-nucleotidase in a biological 5 Prime Nucleotidase Measurement Nucleotidase; specimen. 5'-Ribonucleotid e Phosphohydrolas e

C74876 6-Monoacetylmorphine 6-Monoacetylmo A measurement of the 6-monoacetylmorphine present 6-Monoacetylmorphine rphine in a biological specimen. Measurement

C96565 A Fetoprotein L3/A A Fetoprotein A relative measurement (ratio or percentage) of alpha Alpha Fetoprotein L3 to Total Alpha Fetoprotein L3/A Fetoprotein fetoprotein L3 to total alpha fetoprotein in a biological Fetoprotein Ratio Measurement specimen.

C98705 ADV Viral Load ADV Viral Load A measurement of the adenovirus viral load in a Adenovirus Viral Load Measurement biological specimen.

C74699 Acanthocytes Acanthocytes A measurement of the acanthocytes in a biological Acanthocyte Count specimen.

C74633 Acanthocytes/Erythrocytes Acanthocytes/ A relative measurement (ratio or percentage) of Acanthocyte to Erythrocyte Ratio Erythrocytes acanthocytes to all erythrocytes in a biological Measurement specimen.

C92247 Acetoacetic Acid Acetoacetic A measurement of the acetoacetic acid in a biological Acetoacetic Acid Measurement Acid; specimen. Acetoacetate

C74838 Acetylcholine Acetylcholine A measurement of the acetylcholine hormone in a Acetylcholine Measurement biological specimen.

C96559 Acetylcholine Receptor Acetylcholine A measurement of the acetylcholine receptor antibody Acetylcholine Receptor Antibody Antibody Receptor in a biological specimen. Measurement Antibody

C96560 Acetylcholinesterase Acetylcholineste A measurement of the acetylcholinesterase in a Acetylcholinesterase Measurement rase biological specimen.

C80163 Acid Phosphatase Acid A measurement of the acid phosphatase in a biological Acid Phosphatase Measurement Phosphatase specimen.

C74912 Acid Urate Crystals Acid Urate A measurement of the ammonium acid urate crystals Acid Urate Crystal Measurement Crystals present in a biological specimen.

C98862 Activated PTT/Standard Activated A relative measurement (ratio or percentage) of the Activated PTT/Standard Ratio PTT/Standard subject's partial thromboplastin time to a standard or Measurement control partial thromboplastin time.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 82 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C67154 - LBTEST - Laboratory Test Name Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C100421 Activated PTT/Standard PTT Activated A relative measurement (ratio or percentage) of the Activated PTT to Standard PTT Ratio PTT/Standard subject's activated partial thromboplastin time to a Measurement PTT; Activated standard or control partial thromboplastin time. Partial Thromboplastin Time/Standard Thromboplastin Time

C38462 Activated Partial Activated Partial A measurement of the length of time that it takes for Partial Thromboplastin Time Thromboplastin Time Thromboplastin clotting to occur when reagents are added to a plasma Time specimen. The test is partial due to the absence of tissue factor (Factor III) from the reaction mixture.

C100471 Activated Protein C Activated Protein A measurement of the resistance in the anticoagulation Activated Protein C Resistance Resistance C Resistance; response to activated protein C in a biological Measurement Factor V Leiden specimen. Screen

C92286 Acyl Coenzyme A Oxidase Acyl Coenzyme A measurement of the acyl coenzyme A oxidase in a Acyl Coenzyme A Oxidase A Oxidase; Fatty biological specimen. Measurement Acyl Coenzyme A Oxidase; Acyl CoA Oxidase

C74839 Adiponectin Adiponectin A measurement of the adiponectin hormone in a Adiponectin Measurement biological specimen.

C74780 Adrenocorticotropic Adrenocorticotr A measurement of the adrenocorticotropic hormone in Adrenocorticotropic Hormone Hormone opic Hormone a biological specimen. Measurement

C100430 Alanine Aminopeptidase Alanine A measurement of the alanine aminopeptidase in a Alanine Aminopeptidase Aminopeptidase biological specimen. Measurement

C64433 Alanine Aminotransferase Alanine A measurement of the alanine aminotransferase in a Alanine Aminotransferase Aminotransferas biological specimen. Measurement e; SGPT

C64431 Albumin Albumin; A measurement of the albumin protein in a biological Albumin Measurement Microalbumin specimen.

C74761 Albumin/Creatinine Albumin/ A relative measurement (ratio or percentage) of the Albumin To Creatinine Protein Ratio Creatinine; albumin to the creatinine in a biological specimen. Measurement Microalbumin/ Creatinine Ratio

C74894 Albumin/Globulin Albumin/ The ratio of albumin to globulin in a biological Albumin to Globulin Ratio Globulin specimen. Measurement

C74731 Aldolase Aldolase A measurement of the aldolase enzyme in a biological Aldolase Measurement specimen.

C74841 Aldosterone Aldosterone A measurement of the aldosterone hormone in a Aldosterone Measurement biological specimen.

C64432 Alkaline Phosphatase Alkaline A measurement of the alkaline phosphatase in a Alkaline Phosphatase Measurement Phosphatase biological specimen.

C79438 Alkaline Alkaline A relative measurement (ratio or percentage) of the Alkaline Phosphatase to Creatinine Phosphatase/Creatinine Phosphatase/ alkaline phosphatase to creatinine in a biological Ratio Measurement Creatinine specimen.

C74732 Alpha Fetoprotein Alpha A measurement of the alpha fetoprotein in a biological Alpha-fetoprotein Measurement Fetoprotein specimen.

C96562 Alpha Fetoprotein L1 Alpha A measurement of the alpha fetoprotein L1 in a Alpha Fetoprotein L1 Measurement Fetoprotein L1 biological specimen.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 83 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C67154 - LBTEST - Laboratory Test Name Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C96563 Alpha Fetoprotein L2 Alpha A measurement of the alpha fetoprotein L2 in a Alpha Fetoprotein L2 Measurement Fetoprotein L2 biological specimen.

C96564 Alpha Fetoprotein L3 Alpha A measurement of the alpha fetoprotein L3 in a Alpha Fetoprotein L3 Measurement Fetoprotein L3 biological specimen.

C79433 Alpha Alpha A measurement of the alpha form of glutathione Alpha Glutathione-S-Transferase Glutathione-S-Transferase Glutathione-S-Tr S-transferase in a biological specimen. Measurement ansferase

C100429 Alpha-1 Acid Glycoprotein Alpha-1 Acid A measurement of the alpha-1 acid glycoprotein in a Alpha-1 Acid Glycoprotein Glycoprotein biological specimen. Measurement

C80167 Alpha-1 Antitrypsin Alpha-1 A measurement of the alpha-1 antitrypsin in a Alpha-1 Antitrypsin Measurement Antitrypsin; biological specimen. Serum Trypsin Inhibitor

C92252 Alpha-1 Globulin Alpha-1 A measurement of the proteins contributing to the Alpha-1 Globulin Measurement Globulin; alpha 1 fraction in a biological specimen. A1-Globulin

C92253 Alpha-1 Globulin/Total Alpha-1 A relative measurement (ratio or percentage) of Alpha-1 Globulin to Total Protein Protein Globulin/Total alpha-1-fraction proteins to total proteins in a Ratio Measurement Protein biological specimen.

C100461 Alpha-1 Microglobulin Alpha-1 A measurement of the alpha-1 microglobulin in a Alpha-1 Microglobulin Measurement Microglobulin; biological specimen. Protein HC

C100462 Alpha-1 Alpha-1 A relative measurement (ratio or percentage) of the Alpha-1 Microglobulin to Creatinine Microglobulin/Creatinine Microglobulin/ alpha-1 microglobulin to creatinine in a biological Ratio Measurement Creatinine specimen.

C92254 Alpha-2 Globulin Alpha-2 A measurement of the proteins contributing to the Alpha-2 Globulin Measurement Globulin; alpha 2 fraction in a biological specimen. A2-Globulin

C92255 Alpha-2 Globulin/Total Alpha-2 A relative measurement (ratio or percentage) of Alpha-2 Globulin to Total Protein Protein Globulin/Total alpha-2-fraction proteins to total proteins in a Ratio Measurement Protein biological specimen.

C80168 Alpha-2 Macroglobulin Alpha-2 A measurement of the alpha-2 macroglobulin in a Alpha-2 Macroglobulin Macroglobulin biological specimen. Measurement

C74799 Ammonia Ammonia; NH3 A measurement of the ammonia in a biological Ammonia Measurement specimen.

C74758 Ammonium Biurate Crystals Ammonium A measurement of the ammonium biurate crystals Urine Ammonium Biurate Crystal Biurate Crystals present in a biological specimen. Measurement

C74759 Ammonium Oxalate Crystals Ammonium A measurement of the ammonium oxalate crystals Urine Ammonium Oxalate Crystal Oxalate Crystals present in a urine specimen. Measurement

C74665 Amorphous Crystals Amorphous A measurement of the amorphous (Note: phosphate or Amorphous Crystal Measurement Crystals urate, depending on pH) crystals present in a biological specimen.

C92243 Amorphous Phosphate Amorphous A measurement of the amorphous phosphate crystals Amorphous Phosphate Crystals Crystals Phosphate in a biological specimen. Measurement Crystals

C74666 Amorphous Sediment Amorphous A measurement of the amorphous sediment present in Amorphous Sediment Measurement Sediment; a biological specimen. Amorphous Debris

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 84 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C67154 - LBTEST - Laboratory Test Name Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C92244 Amorphous Urate Crystals Amorphous A measurement of the amorphous urate crystals in a Amorphous Urate Crystals Urate Crystals biological specimen. Measurement

C74687 Amphetamine Amphetamine A measurement of any amphetamine class drug present Amphetamine Drug Class in a biological specimen. Measurement

C64434 Amylase Amylase A measurement of the total enzyme amylase in a Amylase Measurement biological specimen.

C98767 Amylase, Pancreatic Amylase, A measurement of the pancreatic enzyme amylase in a Pancreatic Amylase Measurement Pancreatic biological specimen.

C98780 Amylase, Salivary Amylase, A measurement of the salivary enzyme amylase in a Salivary Amylase Measurement Salivary biological specimen.

C84809 Amyloid Beta 42 Amyloid Beta A measurement of the 42 amino acid amyloid beta Beta Amyloid 42 Measurement 42; Amyloid protein isoform in a biological specimen. Beta 42 Protein

C81998 Amyloid P Amyloid P A measurement of the total amyloid P in a biological Amyloid P Measurement specimen.

C81999 Amyloid, Beta Amyloid, Beta; A measurement of the total amyloid beta in a Beta Amyloid Measurement Beta Amyloid biological specimen.

C74842 Androstenediol Androstenediol A measurement of the androstenediol metabolite in a Androstenediol Metabolite biological specimen. Measurement

C74843 Androstenedione Androstenedione A measurement of the androstenedione hormone in a Androstenedione Measurement ; biological specimen. 4-Androstenedio ne

C80169 Angiotensin Converting Angiotensin A measurement of the angiotensin converting enzyme Angiotensin Converting Enzyme Enzyme Converting in a biological specimen. Measurement Enzyme

C74844 Angiotensin I Angiotensin I A measurement of the angiotensin I hormone in a Angiotensin I Measurement biological specimen.

C74845 Angiotensin II Angiotensin II A measurement of the angiotensin II hormone in a Angiotensin II Measurement biological specimen.

C74846 Angiotensinogen Angiotensinogen; A measurement of the angiotensinogen hormone in a Angiotensinogen Measurement Angiotensin biological specimen. Precursor

C74685 Anion Gap Anion Gap A computed estimate of the unmeasured anions (those Anion Gap Measurement other than the chloride and bicarbonate anions) in a biological specimen.

C74797 Anisocytes Anisocytes A measurement of the inequality in the size of the red Anisocyte Measurement blood cells in a whole blood specimen.

C81973 Anti-DNA Antibodies Anti-DNA A measurement of the anti-DNA antibodies in a Anti-DNA Antibody Measurement Antibodies; biological specimen. Anti-ds-DNA Antibodies

C74913 Anti-Double Stranded DNA Anti-Double A measurement of the anti-double stranded DNA Anti-Double Stranded DNA Stranded DNA antibody in a biological specimen. Measurement

C98706 Anti-Factor Xa Activity Anti-Factor Xa A measurement of the anti-activated Factor X in a Anti-Factor Xa Activity Activity biological specimen. This test is used to monitor low Measurement molecular weight or unfractionated heparin levels in a biological specimen.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 85 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C67154 - LBTEST - Laboratory Test Name Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C81976 Anti-Saccharomyces Anti-Saccharomy A measurement of the anti-Saccharomyces cerevisiae Anti-Saccharomyces cerevisiae cerevisiae Antibody ces cerevisiae antibody in a biological specimen. Antibody Measurement Antibody

C92269 Anti-Single Stranded DNA IgG Anti-Single A measurement of the anti-single stranded DNA IgG Anti-Single Stranded DNA IgG Stranded DNA antibody in a biological specimen. Measurement IgG

C74691 Antidepressants Antidepressants A measurement of any antidepressant class drug Antidepressant Measurement present in a biological specimen.

C74847 Antidiuretic Hormone Antidiuretic A measurement of the antidiuretic hormone in a Antidiuretic Hormone Measurement Hormone; biological specimen. Vasopressin

C81974 Antiglobulin Test, Direct Antiglobulin A measurement of the antibody or complement-coated Direct Antiglobulin Test Test, Direct; erythrocytes in a biological specimen in vivo. Direct Coombs Test

C81975 Antimitochondrial Antibodies Antimitochondri A measurement of the antimitochondrial antibodies in Antimitochondrial Antibody al Antibodies; a biological specimen. Measurement Mitochondrial Antibody

C74916 Antinuclear Antibodies Antinuclear A measurement of the antinuclear antibodies Antinuclear Antibody Measurement Antibodies (antibodies that attack the body's own tissue) in a biological specimen.

C81958 Antithrombin Antithrombin; A measurement of the antithrombin activity in a Antithrombin Measurement Antithrombin III; biological specimen. Antithrombin Activity; Antithrombin III Activity

C81977 Antithrombin Antigen Antithrombin A measurement of the antithrombin antigen in a Antithrombin Antigen Measurement Antigen; biological specimen. Antithrombin III Antigen

C74733 Apolipoprotein A1 Apolipoprotein A measurement of the apolipoprotein A1 in the high Apolipoprotein A1 Measurement A1 density lipoproteins of a biological specimen.

C82000 Apolipoprotein AII Apolipoprotein A measurement of the apolipoprotein AII in a Apolipoprotein AII Measurement AII biological specimen.

C74734 Apolipoprotein B Apolipoprotein B A measurement of the apolipoprotein B in the low Apolipoprotein B Measurement density lipoproteins of a biological specimen.

C100427 Apolipoprotein C2 Apolipoprotein A measurement of the apolipoprotein C2 in a Apolipoprotein C2 Measurement C2; biological specimen. Apolipoprotein CII

C82001 Apolipoprotein CIII Apolipoprotein A measurement of the apolipoprotein CIII in a Apolipoprotein CIII Measurement CIII biological specimen.

C82002 Apolipoprotein E Apolipoprotein E A measurement of the apolipoprotein E in a biological Apolipoprotein E Measurement specimen.

C92293 Apolipoprotein E4 Apolipoprotein A measurement of the apolipoprotein E4 in a Apolipoprotein E4 Measurement E4 biological specimen.

C82003 Apolipoprotein H Apolipoprotein A measurement of the apolipoprotein H in a biological Apolipoprotein H Measurement H specimen.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 86 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C67154 - LBTEST - Laboratory Test Name Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C100428 Apolipoprotein J Apolipoprotein J; A measurement of the apolipoprotein J in a biological Apolipoprotein J Measurement Clusterin specimen.

C64467 Aspartate Aminotransferase Aspartate A measurement of the aspartate aminotransferase in a Aspartate Aminotransferase Aminotransferas biological specimen. Measurement e; SGOT

C81978 Aspartate Aminotransferase Aspartate A measurement of the aspartate aminotransferase Aspartate Aminotransferase Antigen Antigen Aminotransferas antigen in a biological specimen. Measurement e Antigen; SGOT Antigen

C74886 Atrial Natriuretic Peptide Atrial Natriuretic A measurement of the atrial natriuretic peptide in a Atrial Natriuretic Peptide Peptide; biological specimen. Measurement Atriopeptin

C74657 Auer Rods Auer Rods A measurement of the Auer rods (elongated needle Auer Rod Measurement structures that are found in the cytoplasm of leukemic blasts and are formed by clumps of azurophilic granular material) in a biological specimen.

C98710 BKV Viral Load BKV Viral Load A measurement of the BK virus viral load in a BK Virus Viral Load Measurement biological specimen.

C74753 BUN/Creatinine BUN/Creatinine A relative measurement (ratio or percentage) (ratio) of Blood Urea Nitrogen To Creatinine the blood urea nitrogen (BUN) to the creatinine in a Ratio Measurement biological specimen.

C64469 Bacteria Bacteria A measurement of the bacteria in a biological Bacterial Count specimen.

C74762 Bacterial Casts Bacterial Casts A measurement of the bacterial casts present in a Bacterial Cast Measurement biological specimen.

C74688 Barbiturates Barbiturates A measurement of any barbiturate class drug present in Barbiturate Drug Class Measurement a biological specimen.

C96567 Basophilic Stippling Basophilic A measurement of the basophilic stippling in a Basophilic Stippling Measurement Stippling biological specimen.

C64470 Basophils Basophils A measurement of the basophils in a biological Total Basophil Count specimen.

C64471 Basophils/Leukocytes Basophils/ A relative measurement (ratio or percentage) of the Basophil To Leukocyte Ratio Leukocytes basophils to leukocytes in a biological specimen.

C98865 Basophils/Total Cells Basophils/Total A relative measurement (ratio or percentage) of the Basophil to Total CellRatio Cells basophils to total cells in a biological specimen (for Measurement example a bone marrow specimen).

C74692 Benzodiazepine Benzodiazepine A measurement of any benzodiazepine class drug Benzodiazepine Measurement present in a biological specimen.

C75350 Benzoylecgonine Benzoylecgonine A measurement of the benzoylecgonine in a biological Benzoylecgonine Measurement ; Cocaine specimen. Metabolite

C100472 Beta Carotene Beta Carotene; A measurement of the beta carotene in a biological Beta Carotene Measurement b-Carotene; Beta specimen. Carotin

C92256 Beta Globulin Beta Globulin A measurement of the proteins contributing to the beta Beta Globulin Measurement fraction in a biological specimen.

C92294 Beta Globulin/Total Protein Beta A relative measurement (ratio or percentage) of beta Beta Globulin to Total Protein Ratio Globulin/Total fraction proteins to total proteins in a biological Measurement Protein specimen.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 87 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C67154 - LBTEST - Laboratory Test Name Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C81979 Beta-2 Glycoprotein Antibody Beta-2 A measurement of the beta-2 glycoprotein antibody in Beta-2 Glycoprotein Antibody Glycoprotein a biological specimen. Measurement Antibody

C81980 Beta-2 Microglobulin Beta-2 A measurement of the beta-2 microglobulin in a Beta-2 Microglobulin Measurement Microglobulin biological specimen.

C96568 Beta-Hydroxybutyrate Beta-Hydroxybut A measurement of the total Beta-hydroxybutyrate in a Beta-Hydroxybutyrate Measurement yrate; biological specimen. B-Hydroxybutyra te; 3-Hydroxybutyra te

C100426 Beta-Trace Protein Beta-Trace A measurement of the beta-trace protein in a Beta-Trace Protein Measurement Protein biological specimen.

C74667 Bicarbonate Bicarbonate; A measurement of the bicarbonate in a biological Bicarbonate Measurement HCO3 specimen.

C74800 Bile Acid Bile Acid; Bile A measurement of the total bile acids in a biological Bile Acid Measurement Salts; Bile Acids; specimen. Bile Salt

C38037 Bilirubin Bilirubin; Total A measurement of the total bilirubin in a biological Total Bilirubin Measurement Bilirubin specimen.

C74668 Bilirubin Crystals Bilirubin A measurement of the bilirubin crystals present in a Bilirubin Crystal Measurement Crystals biological specimen.

C74700 Bite Cells Bite Cells A measurement of the bite cells (erythrocytes with the Bite Cell Count appearance of a bite having been removed, due to oxidative hemolysis) in a biological specimen .

C74634 Bite Cells/Erythrocytes Bite A relative measurement (ratio or percentage) of bite Bite Cell to Erythrocyte Ratio Cells/ cells (erythrocytes with the appearance of a bite having Measurement Erythrocytes been removed, due to oxidative hemolysis) to all erythrocytes in a biological specimen .

C74605 Blasts Blasts A measurement of the blast cells in a biological Blast Count specimen.

C64487 Blasts/Leukocytes Blasts/ A relative measurement (ratio or percentage) of the Blast To Leukocyte Ratio Leukocytes blasts to leukocytes in a biological specimen.

C61019 Blood Urea Nitrogen Blood Urea A measurement of the urea nitrogen in a blood Blood Urea Nitrogen Measurement Nitrogen specimen.

C92287 Bone Specific Alkaline Bone Specific A measurement of the bone specific alkaline Bone Specific Alkaline Phosphatase Phosphatase Alkaline phosphatase isoform in a biological specimen. Measurement Phosphatase

C74735 Brain Natriuretic Peptide Brain Natriuretic A measurement of the brain (B-type) natriuretic Brain Natriuretic Peptide Peptide; B-Type peptide in a biological specimen. Measurement Natriuretic Peptide

C82004 Brain-Derived Neurotrophic Brain-Derived A measurement of the brain-derived neurotrophic Brain-Derived Neurotrophic Factor Factor Neurotrophic factor in a biological specimen. Measurement Factor

C96588 Broad Casts Broad Casts A measurement of the broad casts in a biological Broad Casts Measurement specimen.

C74701 Burr Cells Burr Cells; A measurement of the Burr cells (erythrocytes Burr Cell Count Keratocytes characterized by the presence of small, blunt projections evenly distributed across the cell surface) in a biological specimen.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 88 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C67154 - LBTEST - Laboratory Test Name Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C64548 C Reactive Protein C Reactive A measurement of the C reactive protein in a C-Reactive Protein Measurement Protein biological specimen.

C74736 C-peptide C-peptide A measurement of the C (connecting) peptide of C-peptide Measurement insulin in a biological specimen.

C74606 CD19 CD19 A measurement of the CD19 B cells in a biological CD19 Expressing B Cell Count specimen.

C74635 CD19/Lymphocytes CD19/ A relative measurement (ratio or percentage) of CD19 CD19 B Cell to Lymphocyte Ratio Lymphocytes B cells to all lymphocytes in a biological specimen. Measurement

C74607 CD3 CD3 A measurement of the CD3 T cells in a biological CD3 Expressing T Cell Count specimen.

C74636 CD3/Lymphocytes CD3/ A relative measurement (ratio or percentage) of CD3 T CD3 T Cell to Lymphocyte Ratio Lymphocytes cells to all lymphocytes in a biological specimen. Measurement

C74608 CD4 CD4 A measurement of the CD4 T cells in a biological CD4 Expressing T Cell Count specimen.

C74637 CD4/CD8 CD4/CD8 A relative measurement (ratio or percentage) of CD4 T CD4 T Cell to CD8 T Cell Ratio cells to the CD8 T cells in a biological specimen. Measurement

C74638 CD4/Lymphocytes CD4/ A relative measurement (ratio or percentage) of CD4 T CD4 T Cell to Lymphocyte Ratio Lymphocytes cells to all lymphocytes in a biological specimen. Measurement

C82006 CD40 CD40 A measurement of the CD40 in a biological specimen. CD40 Measurement

C82007 CD40 Ligand CD40 Ligand A measurement of the CD40 ligand in a biological CD40 Ligand Measurement specimen.

C74609 CD8 CD8 A measurement of the CD8 T cells in a biological CD8 Expressing T Cell Count specimen.

C74639 CD8/Lymphocytes CD8/ A relative measurement (ratio or percentage) of CD8 T CD8 T Cell to Lymphocyte Ratio Lymphocytes cells to all lymphocytes in a biological specimen. Measurement

C98716 CMV Viral Load CMV Viral Load A measurement of the cytomegalovirus viral load in a Cytomegalovirus Viral Load biological specimen. Measurement

C74702 Cabot Rings Cabot Rings A measurement of the Cabot rings (red-purple staining, Cabot Ring Count threadlike, ring or figure 8 shaped filaments in an erythrocyte) in a biological specimen.

C74848 Calcitonin Calcitonin A measurement of the calcitonin hormone in a Calcitonin Measurement biological specimen.

C74849 Calcitriol Calcitriol A measurement of the calcitriol hormone in a Calcitriol Measurement biological specimen.

C64488 Calcium Calcium A measurement of the calcium in a biological Calcium Measurement specimen.

C74669 Calcium Carbonate Crystals Calcium A measurement of the calcium carbonate crystals Calcium Carbonate Crystal Carbonate present in a biological specimen. Measurement Crystals

C96589 Calcium Clearance Calcium A measurement of the volume of serum or plasma that Calcium Clearance Measurement Clearance would be cleared of calcium by excretion of urine for a specified unit of time (e.g. one minute).

C74670 Calcium Oxalate Crystals Calcium Oxalate A measurement of the calcium oxalate crystals present Calcium Oxalate Crystal Crystals in a biological specimen. Measurement

C74671 Calcium Phosphate Crystals Calcium A measurement of the calcium phosphate crystals Calcium Phosphate Crystal Phosphate present in a biological specimen. Measurement Crystals

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 89 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C67154 - LBTEST - Laboratory Test Name Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C96590 Calcium Sulphate Calcium Sulphate A measurement of the calcium sulphate in a biological Calcium Sulphate Measurement specimen.

C81948 Calcium, Ionized Calcium, Ionized A measurement of the ionized calcium in a biological Ionized Calcium Measurement specimen.

C79439 Calcium/Creatinine Calcium/ A relative measurement (ratio or percentage) of the Calcium to Creatinine Ratio Creatinine calcium to creatinine in a biological specimen. Measurement

C82005 Calprotectin Calprotectin A measurement of the calprotectin in a biological Calprotectin Measurement specimen.

C81981 Cancer Antigen 125 Cancer Antigen A measurement of the cancer antigen 125 in a Cancer Antigen 125 Measurement 125 biological specimen.

C81982 Cancer Antigen 19-9 Cancer Antigen A measurement of the cancer antigen 19-9 in a Cancer Antigen 19-9 Measurement 19-9 biological specimen.

C74689 Cannabinoids Cannabinoids A measurement of any cannabinoid class drug present Cannabinoid Drug Class in a biological specimen. Measurement

C101016 Carbohydrate-Deficient Carbohydrate-De A measurement of transferrin with a reduced number Carbohydrate-Deficient Transferrin Transferrin ficient of carbohydrate moieties in a biological specimen. Measurement Transferrin

C64545 Carbon Dioxide Carbon Dioxide A measurement of the carbon dioxide gas in a Carbon Dioxide Measurement biological specimen.

C96591 Carboxyhemoglobin Carboxyhemoglo A measurement of the carboxyhemoglobin in a Carboxyhemoglobin Measurement bin biological specimen.

C81983 Carcinoembryonic Antigen Carcinoembryoni A measurement of the carcinoembryonic antigen in a Carcinoembryonic Antigen c Antigen biological specimen. Measurement

C74682 Carnitine Carnitine A measurement of the total carnitine in a biological Total Carnitine Measurement specimen.

C92288 Carnitine Acetyl Transferase Carnitine Acetyl A measurement of the carnitine acetyl transferase in a Carnitine Acetyl Transferase Transferase biological specimen. Measurement

C74677 Carnitine, Free Carnitine, Free A measurement of the free carnitine in a biological Free Carnitine Measurement specimen.

C74763 Casts Casts A statement that indicates casts were looked for and Cast Present Or Absent not found in a biological specimen.

C74764 Cellular Casts Cellular Casts A measurement of the cellular (white blood cell, red Cellular Cast Measurement blood cell, epithelial and bacterial) casts present in a biological specimen.

C100432 Ceruloplasmin Ceruloplasmin; A measurement of ceruloplasmin in a biological Ceruloplasmin Measurement Caeruloplasmin specimen.

C100431 Chemokine (C-X-C Motif) Chemokine A measurement of the CXCR3, chemokine (C-X-C Chemokine Receptor CXCR3 Receptor 3 (C-X-C Motif) motif) receptor 3, in a biological specimen. Measurement Receptor 3; GPR9, CD183, CXCR3

C92432 Chlamydia pneumoniae IgA Chlamydia A measurement of the Chlamydia pneumoniae IgA Chlamydia pneumoniae IgA Antibody Antibody pneumoniae IgA antibody in a biological specimen. Measurement Antibody

C92433 Chlamydia pneumoniae IgM Chlamydia A measurement of the Chlamydia pneumoniae IgM in a Chlamydia pneumoniae IgM Antibody pneumoniae IgM biological specimen. Antibody Measurement Antibody

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 90 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C67154 - LBTEST - Laboratory Test Name Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C100464 Chlamydia trachomatis IgA Chlamydia A measurement of the Chlamydia trachomatis IgA Chlamydia trachomatis IgA Antibody Antibody trachomatis IgA antibody in a biological specimen. Measurement Antibody

C100466 Chlamydia trachomatis IgG Chlamydia A measurement of the Chlamydia trachomatis IgG Chlamydia trachomatis IgG Antibody Antibody trachomatis IgG antibody in a biological specimen. Measurement Antibody

C100465 Chlamydia trachomatis IgM Chlamydia A measurement of the Chlamydia trachomatis IgM Chlamydia trachomatis IgM Antibody Antibody trachomatis IgM antibody in a biological specimen. Measurement Antibody

C64495 Chloride Chloride A measurement of the chloride in a biological Chloride Measurement specimen.

C79440 Chloride/Creatinine Chloride/ A relative measurement (ratio or percentage) of the Chloride to Creatinine Ratio Creatinine chloride to creatinine in a biological specimen. Measurement

C74850 Cholecystokinin Cholecystokinin; A measurement of the cholecystokinin hormone in a Cholecystokinin Measurement Pancreozymin biological specimen.

C61032 Cholesterol Cholesterol; A measurement of the cholesterol in a biological Serum Total Cholesterol Total specimen. Measurement Cholesterol

C74672 Cholesterol Crystals Cholesterol A measurement of the cholesterol crystals present in a Cholesterol Crystal Measurement Crystals biological specimen.

C80171 Cholesterol/HDL-Cholesterol Cholesterol/ A relative measurement (ratio or percentage) of total Cholesterol to HDL-Cholesterol HDL-Cholestero cholesterol to high-density lipoprotein cholesterol Ratio Measurement l (HDL-C) in a biological specimen.

C92289 Cholinesterase Cholinesterase A measurement of the cholinesterase in a biological Cholinesterase Measurement specimen.

C64851 Choriogonadotropin Beta Choriogonadotro A measurement of the Choriogonadotropin Beta in a Choriogonadotropin Beta pin Beta; biological specimen. Measurement Pregnancy Test

C96592 Circulating Endothelial Cells Circulating A measurement of the circulating endothelial cells in a Circulating Endothelial Cell Count Endothelial Cells biological specimen.

C96593 Circulating Tumor Cells Circulating A measurement of the circulating tumor cells in a Circulating Tumor Cell Count Tumor Cells biological specimen.

C92248 Citrate Citrate A measurement of the citrate in a biological specimen. Citrate Measurement

C96594 Clarity Clarity A measurement of the transparency of a biological Clarity Measurement specimen.

C74690 Cocaine Cocaine A measurement of the cocaine present in a biological Cocaine Measurement specimen.

C74877 Codeine Codeine A measurement of the codeine present in a biological Codeine Measurement specimen.

C64546 Color Color A measurement of the color of a biological specimen. Color Assessment

C80172 Complement Bb Complement Bb A measurement of the complement Bb in a biological Complement Bb Measurement specimen.

C80173 Complement C1q Antibody Complement A measurement of the complement C1q antibody in a Complement C1q Antibody C1q Antibody biological specimen. Measurement

C80174 Complement C3 Complement C3 A measurement of the complement C3 in a biological Complement C3 Measurement specimen.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 91 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C67154 - LBTEST - Laboratory Test Name Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C80175 Complement C3a Complement A measurement of the complement C3a in a biological Complement C3a Measurement C3a; ASP, specimen. Complement C3 DesArg, Acetylation-stim ulating Protein

C80176 Complement C3b Complement A measurement of the complement C3b in a biological Complement C3b Measurement C3b specimen.

C80177 Complement C4 Complement C4 A measurement of the complement C4 in a biological Complement C4 Measurement specimen.

C80178 Complement C4a Complement C4a A measurement of the complement C4a in a biological Complement C4a Measurement specimen.

C80179 Complement C5a Complement C5a A measurement of the complement C5a in a biological Complement C5a Measurement specimen.

C100423 Complement CH50 Complement A measurement of the complement required to lyse 50 CH50 Measurement CH50; Total percent of red blood cells in a biological specimen. Hemolytic Complement; CH50

C80160 Complement Total Complement A measurement of the total complement in a Complement Measurement Total biological specimen.

C79434 Corticosterone Corticosterone A measurement of corticosterone in a biological Corticosterone Measurement specimen.

C74851 Corticotropin Releasing Corticotropin A measurement of the corticotropin releasing Corticotropin Releasing Hormone Hormone Releasing hormone in a biological specimen. Measurement Hormone; Corticotropin Releasing Factor

C74781 Cortisol Cortisol; Total A measurement of the cortisol in a biological Cortisol Measurement Cortisol specimen.

C88113 Cortisol, Free Cortisol, Free A measurement of the free, unbound cortisol in a Free Cortisol Measurement biological specimen.

C92249 Cotinine Cotinine A measurement of the cotinine in a biological Cotinine Measurement specimen.

C64489 Creatine Kinase Creatine Kinase A measurement of the total creatine kinase in a Creatine Kinase Measurement biological specimen.

C64490 Creatine Kinase BB Creatine Kinase A measurement of the homozygous B-type creatine Creatine Kinase BB Measurement BB kinase in a biological specimen.

C79466 Creatine Kinase BB/Total Creatine Kinase A relative measurement (ratio or percentage) of the Creatine Kinase BB to Total Creatine Creatine Kinase BB/Total BB-type creatine kinase to total creatine kinase in a Kinase Ratio Measurement Creatine Kinase biological specimen.

C64491 Creatine Kinase MB Creatine Kinase A measurement of the heterozygous MB-type creatine Creatine Kinase MB Measurement MB kinase in a biological specimen.

C79441 Creatine Kinase MB/Total Creatine Kinase A relative measurement (ratio or percentage) of the Creatine Kinase MB to Total Creatine Kinase MB/Total MB-type creatine kinase to total creatine kinase in a Creatine Kinase Ratio Measurement Creatine Kinase biological specimen.

C64494 Creatine Kinase MM Creatine Kinase A measurement of the homozygous M-type creatine Creatine Kinase MM Measurement MM kinase in a biological specimen.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 92 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C67154 - LBTEST - Laboratory Test Name Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C79442 Creatine Kinase MM/Total Creatine Kinase A relative measurement (ratio or percentage) of the Creatine Kinase MM to Total Creatine Kinase MM/Total MM-type creatine kinase to total creatine kinase in a Creatine Kinase Ratio Measurement Creatine Kinase biological specimen.

C64547 Creatinine Creatinine A measurement of the creatinine in a biological Creatinine Measurement specimen.

C25747 Creatinine Clearance Creatinine A measurement of the volume of serum or plasma that Creatinine Clearance Clearance would be cleared of creatinine by excretion of urine for a specified unit of time (e.g. one minute).

C74703 Crenated Cells Crenated Cells; A measurement of the Burr cells (erythrocytes Crenated Cell Measurement Echinocytes characterized by the presence of multiple small, sharp projections evenly distributed across the cell surface) in a biological specimen.

C74673 Crystals Crystals A statement that indicates crystals were looked for and Crystal Present Or Absent not found in a biological specimen.

C96595 Cyclic Citrullinated Peptide Cyclic A measurement of the cyclic citrullinated peptide Cyclic Citrullinated Peptide Antibody Citrullinated antibody in a biological specimen. Antibody Measurement Peptide Antibody

C92290 Cystatin C Cystatin C A measurement of the cystatin C in a biological Cystatin C Measurement specimen.

C74674 Cystine Crystals Cystine Crystals A measurement of the cystine crystals present in a Cystine Crystal Measurement biological specimen.

C96596 Cytomegalovirus IgG Cytomegalovirus A measurement of the cytomegalovirus IgG antibody Cytomegalovirus IgG Antibody Antibody IgG Antibody in a biological specimen. Measurement

C96597 Cytomegalovirus IgM Cytomegalovirus A measurement of the cytomegalovirus IgM antibody Cytomegalovirus IgM Antibody Antibody IgM Antibody in a biological specimen. Measurement

C82621 D-Dimer D-Dimer A measurement of the d-dimers in a biological D-Dimer Measurement specimen.

C100463 DNase-B Antibody DNase-B A measurement of Dnase-B antibody in a biological DNase-B Antibody Measurement Antibody; specimen. Anti-Dnase B

C100441 DTPA Clearance DTPA Clearance A measurement of the volume of serum or plasma that Diethylene Triamine Pentaacetic would be cleared of Diethylenetriamine pentaacetate Acid Clearance (DTPA) through its excretion for a specified unit of time.

C64801 Dacryocytes Dacryocytes; A measurement of dacryocytes in a biological Dacryocyte Analysis Tear Shaped specimen. Erythrocytes; Teardrop Cells

C74852 Dehydroepiandrosterone Dehydroepiandro A measurement of the dehydroepiandrosterone Dehydroepiandrosterone sterone; hormone in a biological specimen. Measurement Dehydroisoandro sterone

C96629 Dehydroepiandrosterone Dehydroepiandro A measurement of the sulfated Sulfated DHEA Measurement Sulfate sterone Sulfate; Dehydroepiandrosterone in a biological specimen. DHEA-S; sDHEA; DHEA Sulfate

C79443 Deoxypyridinoline Deoxypyridinoli A measurement of the deoxypyridinoline in a Deoxypyridinoline Measurement ne biological specimen.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 93 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C67154 - LBTEST - Laboratory Test Name Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C79444 Deoxypyridinoline/Creatinine Deoxypyridinoli A relative measurement (ratio or percentage) of the Deoxypyridinoline to Creatinine ne/Creatinine deoxypyridinoline to creatinine in a biological Ratio Measurement specimen.

C74878 Dihydrocodeine Dihydrocodeine A measurement of the dihydrocodeine present in a Dihydrocodeine Measurement biological specimen.

C74853 Dihydrotestosterone Dihydrotestoster A measurement of the dihydrotestosterone hormone in Dihydrotestosterone Measurement one; a biological specimen. Androstanalone

C96696 Dilute Russell's Viper Venom Dilute Russell's A measurement of the time it takes a plasma sample to Dilute Russell's Viper Venom Time Time Viper Venom clot after adding dilute Russell's viper venom. Measurement Time

C64481 Direct Bilirubin Direct Bilirubin A measurement of the conjugated or water-soluble Direct Bilirubin Measurement bilirubin in a biological specimen.

C74610 Dohle Bodies Dohle Bodies A measurement of the Dohle bodies (blue-gray, Dohle Body Measurement basophilic, leukocyte inclusions located in the peripheral cytoplasm of neutrophils) in a biological specimen.

C74854 Dopamine Dopamine A measurement of the dopamine hormone in a Dopamine Measurement biological specimen.

C98721 EBV Viral Load EBV Viral Load A measurement of the Epstein-Barr virus viral load in a Epstein-Barr Virus Viral Load biological specimen. Measurement

C100440 EDTA Clearance EDTA Clearance A measurement of the volume of serum or plasma that EDTA Clearance would be cleared of Ethylenediamine tetraacetic acid (EDTA) through its excretion for a specified unit of time.

C100422 Ecarin Clotting Time Ecarin Clotting A measurement of the activity of thrombin inhibitors Ecarin Clotting Time Measurement Time in a biological specimen based on the generation of meizothrombin.

C96598 Eccentrocytes Eccentrocytes A measurement of the eccentrocytes (erythrocytes in Eccentrocyte Count which the hemoglobin is localized to a particular portion of the cell, noticeable as localized staining) in a biological specimen.

C64549 Elliptocytes Elliptocytes; A measurement of the elliptically shaped erythrocytes Elliptocyte Count Ovalocytes in a biological specimen.

C82008 Endothelin-1 Endothelin-1 A measurement of the endothelin-1 in a biological Endothelin-1 Measurement specimen.

C84819 Eosinophilic Metamyelocytes Eosinophilic A measurement of the eosinphilic metamyelocytes in a Eosinophilic Metamyelocyte Count Metamyelocytes biological specimen.

C84821 Eosinophilic Myelocytes Eosinophilic A measurement of the eosinophilic myelocytes in a Eosinophilic Myelocyte Count Myelocytes biological specimen.

C64550 Eosinophils Eosinophils A measurement of the eosinophils in a biological Eosinophil Count specimen.

C64604 Eosinophils/Leukocytes Eosinophils/ A relative measurement (ratio or percentage) of the Eosinophil To Leukocyte Ratio Leukocytes eosinophils to leukocytes in a biological specimen.

C98720 Eosinophils/Total Cells Eosinophils/ A relative measurement (ratio or percentage) of the Eosinophils to Total Cell Ratio Total Cells eosinophils to total cells in a biological specimen (for Measurement example a bone marrow specimen).

C81952 Eotaxin-1 Eotaxin-1; A measurement of the eotaxin-1 in a biological Eotaxin-1 Measurement Chemokine specimen. Ligand 11

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 94 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C67154 - LBTEST - Laboratory Test Name Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C81953 Eotaxin-2 Eotaxin-2; A measurement of the eotaxin-2 in a biological Eotaxin-2 Measurement Chemokine specimen. Ligand 24

C81954 Eotaxin-3 Eotaxin-3; A measurement of the eotaxin-3 in a biological Eotaxin-3 Measurement Chemokine specimen. Ligand 26

C82009 Epidermal Growth Factor Epidermal A measurement of the epidermal growth factor in a Epidermal Growth Factor Growth Factor biological specimen. Measurement

C79445 Epinephrine Epinephrine; A measurement of the epinephrine hormone in a Epinephrine Measurement Adrenaline biological specimen.

C82010 Epith Neutrophil-Activating Epith A measurement of the epithelial neutrophil-activating Epithelial Neutrophil-Activating Peptide 78 Neutrophil-Activ peptide in a biological specimen. Peptide 78 Measurement ating Peptide 78

C74779 Epithelial Casts Epithelial Casts A measurement of the epithelial cell casts present in a Epithelial-Cast Measurement biological specimen.

C64605 Epithelial Cells Epithelial Cells A measurement of the epithelial cells in a biological Epithelial Cell Count specimen.

C96600 Epstein-Barr Capsid IgG Epstein-Barr A measurement of the Epstein-Barr capsid IgG Epstein-Barr Capsid IgG Antibody Antibody Capsid IgG antibody in a biological specimen. Measurement Antibody

C96601 Epstein-Barr Capsid IgM Epstein-Barr A measurement of the Epstein-Barr capsid IgM Epstein-Barr Capsid IgM Antibody Antibody Capsid IgM antibody in a biological specimen. Measurement Antibody

C96602 Epstein-Barr Early Antigen Epstein-Barr A measurement of the Epstein-Barr early antigen in a Epstein-Barr Early Antigen Early Antigen biological specimen. Measurement

C96603 Epstein-Barr Nuclear Epstein-Barr A measurement of the Epstein-Barr nuclear antibody in Epstein-Barr Nuclear Antibody Antibody Nuclear a biological specimen. Measurement Antibody

C96604 Epstein-Barr Nuclear Antigen Epstein-Barr A measurement of the Epstein-Barr nuclear antigen in Epstein-Barr Nuclear Antigen Nuclear Antigen a biological specimen. Measurement

C64798 Ery. Mean Corpuscular HGB Ery. Mean A quantitative measurement of the mean amount of Erythrocyte Mean Corpuscular Concentration Corpuscular hemoglobin per erythrocytes in a specified volume of Hemoglobin Concentration HGB a biological specimen. Concentration

C64797 Ery. Mean Corpuscular Ery. Mean A quantitative measurement of the mean amount of Erythrocyte Mean Corpuscular Hemoglobin Corpuscular hemoglobin per erythrocyte in a biological specimen. Hemoglobin Hemoglobin

C64799 Ery. Mean Corpuscular Ery. Mean A quantitative measurement of the mean volume of Erythrocyte Mean Corpuscular Volume Corpuscular erythrocytes in a biological specimen. Volume Volume

C92245 Erythrocyte Cell Clumps Erythrocyte Cell A measurement of red blood cell clumps in a Erythrocyte Cell Clumps Clumps; Red biological specimen. Measurement Blood Cell Clumps; RBC Clumps

C92296 Erythrocyte Cell Morphology Erythrocyte Cell An examination or assessment of the form and Erythrocyte Cell Morphology Morphology; structure of red blood cells. Red Blood Cell Morphology; RBC Morphology

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 95 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C67154 - LBTEST - Laboratory Test Name Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C96605 Erythrocyte Ghosts Erythrocyte A measurement of the erythrocyte ghosts Erythrocyte Ghost Count Ghosts; RBC (erythrocytes in which hemoglobin has been removed Ghosts through hemolysis) in a biological specimen.

C74611 Erythrocyte Sedimentation Erythrocyte The distance (e.g. millimeters) that red blood cells Erythrocyte Sedimentation Rate Rate Sedimentation settle in unclotted blood over a specified unit of time Measurement Rate; Biernacki (e.g. one hour). Reaction

C51946 Erythrocytes Erythrocytes; A measurement of the total erythrocytes in a Erythrocyte Count Red Blood Cells biological specimen.

C64800 Erythrocytes Distribution Erythrocytes A value derived from mean corpuscular volume and the Erythrocyte Distribution Width Width Distribution standard deviation of the red blood cell volume in a Measurement Width whole blood specimen.

C74855 Erythropoietin Erythropoietin; A measurement of the erythropoietin hormone in a Erythropoietin Measurement Hematopoietin biological specimen.

C74782 Estradiol Estradiol; A measurement of the estradiol in a biological Estradiol Measurement Oestradiol specimen.

C74856 Estriol Estriol; Oestriol A measurement of the estriol hormone in a biological Estriol Measurement specimen.

C81963 Estriol, Free Estriol, Free A measurement of the free estriol in a biological Free Estriol Measurement specimen.

C74857 Estrone Estrone; A measurement of the estrone hormone in a biological Estrone Measurement Oestrone specimen.

C74693 Ethanol Ethanol; Alcohol A measurement of the ethanol present in a biological Ethanol Measurement specimen.

C82011 Extracell Newly Ident RAGE Extracell Newly A measurement of the extracellular newly identified Extracell Newly Ident RAGE Bind Bind Protein Ident RAGE Bind RAGE (receptor for advanced glycation end products) Protein Measurement Protein; S100 binding protein in a biological specimen. Calcium Binding Protein A12

C92270 Extractable Nuclear Antigen Anti-ENA; A measurement of the extractable nuclear antigen Extractable Nuclear Antigen Antibody Extractable antibody in a biological specimen. Antibody Measurement Nuclear Antigen Antibody

C80180 F2-Isoprostane F2-Isoprostane A measurement of the F2-isoprostane in a biological F2 Isoprostane Measurement specimen.

C96626 Factor II Factor II; A measurement of the Factor II in a biological Prothrombin Measurement Prothrombin specimen.

C81959 Factor III Factor III; Tissue A measurement of the factor III in a biological Factor III Measurement Factor, CD142 specimen.

C98725 Factor IX Factor IX A measurement of the factor IX in a biological Factor IX Measurement specimen.

C98726 Factor V Factor V A measurement of the factor V in a biological Factor V Measurement specimen.

C81960 Factor VII Factor VII A measurement of the factor VII in a biological Factor VII Measurement specimen.

C81961 Factor VIII Factor VIII A measurement of the factor VIII in a biological Factor VIII Measurement specimen.

C98727 Factor X Factor X A measurement of the factor X in a biological Factor X Measurement specimen.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 96 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C67154 - LBTEST - Laboratory Test Name Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C96648 Fat Fat A measurement of the fat in a biological specimen. Fat Measurement

C81947 Fat Bodies, Oval Fat Bodies, Oval A measurement of the oval-shaped fat bodies, usually Oval Fat Body Measurement renal proximal tubular cells with lipid aggregates in the cytoplasm, in a biological specimen.

C98728 Fat Droplet Fat Droplet A measurement of the triglyceride aggregates within a Fat Droplet Measurement biological specimen.

C82012 Fatty Acid Binding Protein 1 Fatty Acid A measurement of the fatty acid binding protein 1 in a Fatty Acid Binding Protein 1 Binding Protein biological specimen. Measurement 1

C74766 Fatty Casts Fatty Casts A measurement of the fatty casts present in a Fatty Cast Measurement biological specimen.

C74737 Ferritin Ferritin A measurement of the ferritin in a biological Ferritin Measurement specimen.

C82013 Fibrin Degradation Products Fibrin A measurement of the fibrin degradation products in a Fibrin Degradation Products Degradation biological specimen. Measurement Products

C64606 Fibrinogen Fibrinogen A measurement of the fibrinogen in a biological Fibrinogen Measurement specimen.

C96650 Fibroblast Growth Factor 23 Fibroblast A measurement of the fibroblast growth factor 23 in a Fibroblast Growth Factor 23 Growth Factor biological specimen. Measurement 23; Phosphatonin

C82014 Fibroblast Growth Factor Fibroblast A measurement of the basic form of fibroblast growth Fibroblast Growth Factor Basic Basic Form Growth Factor factor in a biological specimen. Form Measurement Basic Form; FGF2

C74783 Follicle Stimulating Hormone Follicle A measurement of the follicle stimulating hormone Follicle Stimulating Hormone Stimulating (FSH) in a biological specimen. Measurement Hormone

C80200 Free Fatty Acid Free Fatty Acid; A measurement of the total non-esterified fatty acids Non-esterified Fatty Acids Non-Esterified in a biological specimen. Measurement Fatty Acid, Free

C80206 Free Fatty Acid, Saturated Free Fatty Acid, A measurement of the saturated non-esterified fatty Saturated Non-esterified Fatty Acids Saturated; acids in a biological specimen. Measurement Non-esterified Fatty Acid, Saturated

C80209 Free Fatty Acid, Unsaturated Free Fatty Acid, A measurement of the unsaturated non-esterified fatty Unsaturated Non-esterified Fatty Unsaturated; acids in a biological specimen. Acids Measurement Non-esterified Fatty Acid, Unsaturated

C100448 Free Glycerol Free Glycerol; A measurement of the amount of unbound glycerol in a Free Glycerol Measurement Free Glycerin biological specimen.

C74678 Fructosamine Fructosamine; A measurement of the fructosamine in a biological Fructosamine Measurement Glycated Serum specimen. Protein

C100450 GFR from B-2 Microglobulin GFR from B-2 A measurement of the glomerular filtration rate (GFR) Glomerular Filtration Rate from B-2 Adj for BSA Microglobulin based on the clearance of beta-2 microglobulin after Microglobulin Adjusted for BSA Adj for BSA adjusting it for the body surface area. Measurement

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 97 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C67154 - LBTEST - Laboratory Test Name Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C100449 GFR from Beta-Trace Protein GFR from A measurement of the glomerular filtration rate (GFR) Glomerular Filtration Rate from Adj for BSA Beta-Trace based on the clearance of beta-trace protein after Beta-Trace Protein Adjusted for BSA Protein Adj for adjusting it for the body surface area. Measurement BSA

C98735 GFR from Creatinine Adjusted GFR from An estimation of the glomerular filtration rate adjusted Glomerular Filtration Rate from for BSA Creatinine for body size based on creatinine. Creatinine Adjusted for BSA Adjusted for BSA

C98736 GFR from Cystatin C Adjusted GFR from An estimation of the glomerular filtration rate adjusted Glomerular Filtration Rate from for BSA Cystatin C for body size based on cystatin C. Cystatin C Adjusted for BSA Adjusted for BSA

C80182 Galanin Galanin A measurement of the galanin in a biological Galanin Measurement specimen.

C92257 Gamma Globulin Gamma Globulin A measurement of the proteins contributing to the Gamma Globulin Measurement gamma fraction in a biological specimen.

C92295 Gamma Globulin/Total Gamma A relative measurement (ratio or percentage) of Gamma Globulin to Total Protein Protein Globulin/Total gamma fraction proteins to total proteins in a Ratio Measurement Protein biological specimen.

C64847 Gamma Glutamyl Transferase Gamma Glutamyl A measurement of the gamma glutamyl transferase in a Gamma Glutamyl Transpeptidase Transferase biological specimen. Measurement

C79446 Gamma Glutamyl Gamma Glutamyl A relative measurement (ratio or percentage) of the Gamma Glutamyl Transferase to Transferase/Creatinine Transferase/ gamma glutamyl transferase to creatinine in a Creatinine Ratio Measurement Creatinine biological specimen.

C74858 Gastrin Gastrin A measurement of the gastrin hormone in a biological Gastrin Measurement specimen.

C96651 Giant Neutrophils Giant A measurement of the giant neutrophils in a biological Giant Neutrophil Count Neutrophils specimen.

C74728 Giant Platelets Giant Platelets A measurement of the giant (larger than 7um in Giant Platelet Count diameter) platelets in a biological specimen.

C74738 Globulin Globulin A measurement of the globulin protein in a biological Globulin Protein Measurement specimen.

C90505 Glomerular Filtration Rate Glomerular A kidney function test that measures the fluid volume Glomerular Filtration Rate Filtration Rate that is filtered from the kidney glomeruli to the Bowman's capsule per unit of time.

C98734 Glomerular Filtration Rate Glomerular A measurement of the glomerular filtration rate Glomerular Filtration Rate Adjusted Adj for BSA Filtration Rate adjusted for body size. for BSA Adj for BSA

C74859 Glucagon Glucagon A measurement of the glucagon hormone in a Glucagon Measurement biological specimen.

C80183 Glucagon-Like Peptide-1 Glucagon-Like A measurement of the total glucagon-like peptide-1 in Glucagon-like Peptide-1 Peptide-1; Total a biological specimen. Measurement Glucagon-Like Peptide-1

C80164 Glucagon-Like Peptide-1, Glucagon-Like A measurement of the active form of glucagon-like Active Glucagon-like Peptide-1 Active Form Peptide-1, Active peptide-1 in a biological specimen. Measurement Form

C41376 Glucose Glucose A measurement of the glucose in a biological Plasma Glucose Measurement specimen.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 98 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C67154 - LBTEST - Laboratory Test Name Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C96652 Glucose Clearance Glucose A measurement of the glucose clearance in a Glucose Clearance Measurement Clearance biological specimen.

C80184 Glucose-6-Phosphate Glucose-6-Phos A measurement of the glucose-6-phosphate Glucose-6-Phosphate Dehydrogenase phate dehydrogenase in a biological specimen. Dehydrogenase Measurement Dehydrogenase

C79447 Glucose/Creatinine Glucose/ A relative measurement (ratio or percentage) of the Glucose to Creatinine Ratio Creatinine glucose to creatinine in a biological specimen. Measurement

C80165 Glucuronidase, Alpha Glucuronidase, A measurement of the alpha glucuronidase in a Alpha Glucuronidase Measurement Alpha biological specimen.

C80170 Glucuronidase, Beta Glucuronidase, A measurement of the beta glucuronidase in a Beta Glucuronidase Measurement Beta biological specimen.

C74739 Glutamate Glutamate; A measurement of the glutamate in a biological Glutamate Measurement Glutamic Acid specimen.

C79448 Glutamate Dehydrogenase Glutamate A measurement of the glutamate dehydrogenase in a Glutamate Dehydrogenase Dehydrogenase biological specimen. Measurement

C82015 Glutamic Acid Decarboxylase Glutamic Acid A measurement of the glutamic acid decarboxylase 1 Glutamic Acid Decarboxylase 1 1 Decarboxylase 1; in a biological specimen. Measurement Glutamic Acid Decarboxylase 67

C82016 Glutamic Acid Decarboxylase Glutamic Acid A measurement of the glutamic acid decarboxylase 2 Glutamic Acid Decarboxylase 2 2 Decarboxylase 2; in a biological specimen. Measurement Glutamic Acid Decarboxylase 65

C82017 Glutamic Acid Decarboxylase Glutamic Acid A measurement of the glutamic acid decarboxylase 2 Glutamic Acid Decarboxylase 2 2 Antibody Decarboxylase 2 antibody in a biological specimen. Antibody Measurement Antibody; Glutamic Acid Decarboxylase 65 Antibody

C96653 Glutamic Acid Decarboxylase Glutamic Acid A measurement of the glutamic acid decarboxylase Glutamic Acid Decarboxylase Antibody Decarboxylase antibody in a biological specimen. Antibody Measurement Antibody; GAD Antibody

C80166 Glutathione S-Transferase, Glutathione A relative measurement (ratio or percentage) of the Alpha Glutathione-S-Transferase to Alpha/Creat S-Transferase, alpha glutathione-S-transferase to creatinine in a Creatinine Ratio Measurement Alpha/Creat biological specimen.

C80203 Glutathione S-Transferase, Pi Glutathione A measurement of the Pi glutathione-s-transferase in a Pi Glutathione S-Transferase S-Transferase, Pi biological specimen. Measurement

C80207 Glutathione S-Transferase, Glutathione A measurement of the theta glutathione-s-transferase Theta Glutathione S-Transferase Theta S-Transferase, in a biological specimen. Measurement Theta

C80185 Glutathione S-Transferase, Glutathione A measurement of the total glutathione-s-transferase Glutathione-S-Transferase Total S-Transferase, in a biological specimen. Measurement Total

C79435 Glutathione-S-Transferase/ Glutathione-S-Tr A relative measurement (ratio or percentage) of the Glutathione-S-Transferase to Creatinine ansferase/ glutathione S-transferase to creatinine in a biological Creatinine Ratio Measurement Creatinine specimen.

C80186 Gold Gold A measurement of the gold in a biological specimen. Gold Measurement

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 99 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C67154 - LBTEST - Laboratory Test Name Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C74860 Gonadotropin Releasing Gonadotropin A measurement of the gonadotropin releasing Gonadotropin Releasing Hormone Hormone Releasing hormone in a biological specimen. Measurement Hormone; Luteinising Hormone Releasing Hormone

C74768 Granular Casts Granular Casts A measurement of the granular (coarse and fine) casts Granular Cast Measurement present in a biological specimen.

C74765 Granular Coarse Casts Granular Coarse A measurement of the coarse granular casts present in Coarse Granular Cast Measurement Casts a biological specimen.

C74769 Granular Fine Casts Granular Fine A measurement of the fine granular casts present in a Granular Fine Cast Measurement Casts biological specimen.

C82018 Granulocyte Colony Granulocyte A measurement of the granulocyte colony stimulating Granulocyte Colony Stimulating Stimulating Factor Colony factor in a biological specimen. Factor Measurement Stimulating Factor

C82019 Granulocyte Macrophage Granulocyte A measurement of the granulocyte macrophage colony Granulocyte Macrophage Colony Colony Stm Factor Macrophage stimulating factor in a biological specimen. Stm Factor Measurement Colony Stm Factor

C96654 Granulocytes Granulocytes A measurement of the granulocytes in a biological Granulocyte Count specimen.

C98866 Granulocytes/Total Cells Granulocytes/ A relative measurement (ratio or percentage) of the Granulocyte to Total CellRatio Total Cells granulocytes to total cells in a biological specimen Measurement (for example a bone marrow specimen).

C74861 Growth Hormone Inhibiting Growth A measurement of the growth hormone inhibiting Growth Hormone Inhibiting Hormone Hormone hormone in a biological specimen. Hormone Measurement Inhibiting Hormone; Somatostatin

C74862 Growth Hormone Releasing Growth A measurement of the growth hormone releasing Growth Hormone Releasing Hormone Hormone hormone in a biological specimen. Hormone Measurement Releasing Hormone; Somatocrinin

C92541 HAV Viral Load HAV Viral Load A measurement of the hepatitis A viral load in a Hepatitis A Viral Load Measurement biological specimen.

C92542 HBV Viral Load HBV Viral Load A measurement of the hepatitis B viral load in a Hepatitis B Viral Load Measurement biological specimen.

C92543 HCV Viral Load HCV Viral Load A measurement of the hepatitis C viral load in a Hepatitis C Viral Load Measurement biological specimen.

C61041 HDL Cholesterol HDL Cholesterol A measurement of the high density lipoprotein Serum HDL Cholesterol cholesterol in a biological specimen. Measurement

C100425 HDL Cholesterol/LDL HDL A relative measurement (ratio or percentage) of the HDL Cholesterol to LDL Cholesterol Ratio Cholesterol/LDL amount of HDL cholesterol compared to LDL Cholesterol Ratio Measurement Cholesterol cholesterol in a biological specimen. Ratio

C80187 HDL-Cholesterol Subclass 2 HDL-Cholestero A measurement of the high-density lipoprotein (HDL) HDL-Cholesterol Subclass 2 l Subclass 2 cholesterol subclass 2 in a biological specimen. Measurement

C80188 HDL-Cholesterol Subclass 3 HDL-Cholestero A measurement of the high-density lipoprotein (HDL) HDL-Cholesterol Subclass 3 l Subclass 3 cholesterol subclass 3 in a biological specimen. Measurement

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 100 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C67154 - LBTEST - Laboratory Test Name Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C92544 HIV Viral Load HIV Viral Load A measurement of the HIV viral load in a biological HIV Viral Load Measurement specimen.

C74713 HIV-1 Antibody HIV-1 Antibody A measurement of the antibody reaction of a HIV-1 Antibody Measurement biological specimen to the HIV-1 virus.

C92263 HIV-1 Group M and O HIV-1 Group M A measurement of the HIV-1 group M and O nucleic HIV-1 Group M and O Nucleic Acid Nucleic Acid and O Nucleic acids in a biological specimen. Measurement Acid

C92264 HIV-1 Group O Antibody HIV-1 Group O A measurement of the HIV-1 group O antibody in a HIV-1 Group O Antibody Antibody biological specimen. Measurement

C92265 HIV-1 p24 Antigen HIV-1 p24 A measurement of the HIV-1 p24 antigen in a HIV-1 p24 Antigen Measurement Antigen biological specimen.

C74714 HIV-1/2 Antibody HIV-1/2 A measurement of the antibody reaction of a HIV-1 HIV-2 Antibody Measurement Antibody biological specimen to the either the HIV-1 or HIV-2 virus.

C74715 HIV-2 Antibody HIV-2 Antibody A measurement of the antibody reaction of a HIV-2 Antibody Measurement biological specimen to the HIV-2 virus.

C92266 HIV-2 Nucleic Acid HIV-2 Nucleic A measurement of the HIV-2 nucleic acids in a HIV-2 Nucleic Acid Measurement Acid biological specimen.

C100460 HLA-B27 Antigen HLA-B27 A measurement of the human leukocyte antigen B27 HLA-B27 Antigen Measurement Antigen; Human (HLA-B27) in a biological specimen. Leukocyte Antigen B27

C74604 Hairy Cells Hairy Cells A measurement of the hairy cells (b-cell lymphocytes Hairy Cell Count with hairy projections from the cytoplasm) in a biological specimen.

C74640 Hairy Cells/Lymphocytes Hairy A relative measurement (ratio or percentage) of the Hairy Cell to Lymphocyte Ratio Cells/ hairy cells (b-cell lymphocytes with hairy projections Measurement Lymphocytes from the cytoplasm) to all lymphocytes in a biological specimen .

C74740 Haptoglobin Haptoglobin A measurement of the haptoglobin protein in a Haptoglobin Protein Measurement biological specimen.

C74709 Heinz Bodies Heinz Bodies; A measurement of the Heinz bodies (small round Heinz-Ehrlich Body Measurement Heinz-Erhlich inclusions within the body of a red blood cell) in a Bodies biological specimen.

C74658 Helmet Cells Helmet Cells A measurement of the Helmet cells (specialized Helmet Cell Count Keratocytes with two projections on either end that are tapered and hornlike) in a biological specimen.

C64796 Hematocrit Hematocrit The percentage of a whole blood specimen that is Hematocrit composed of red blood cells (erythrocytes).

C64848 Hemoglobin Hemoglobin A measurement of the hemoglobin in a biological Hemoglobin Measurement specimen.

C92258 Hemoglobin A Hemoglobin A A measurement of the hemoglobin A in a biological Hemoglobin A Measurement specimen.

C64849 Hemoglobin A1C Hemoglobin A measurement of the glycosylated hemoglobin in a Glycosylated Hemoglobin A1C biological specimen. Measurement

C92259 Hemoglobin A2 Hemoglobin A2 A measurement of the hemoglobin A2 in a biological Hemoglobin A2 Measurement specimen.

C92260 Hemoglobin B Hemoglobin B A measurement of the hemoglobin B in a biological Hemoglobin B Measurement specimen.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 101 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C67154 - LBTEST - Laboratory Test Name Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C92261 Hemoglobin C Hemoglobin C A measurement of the hemoglobin C in a biological Hemoglobin C Measurement specimen.

C92262 Hemoglobin F Hemoglobin F; A measurement of the hemoglobin F in a biological Hemoglobin F Measurement Fetal specimen. Hemoglobin

C96659 Hemosiderin Hemosiderin A measurement of the hemosiderin complex in a - - - biological specimen.

C92534 Hepatitis A Virus Antibody Hepatitis A Virus A measurement of the antibody reaction of a Hepatitis A Antibody Measurement Antibody biological specimen to the Hepatitis A virus.

C92271 Hepatitis A Virus Antibody Hepatitis A Virus A measurement of hepatitis A virus antibody IgM in a Hepatitis A Virus Antibody IgM IgM Antibody IgM biological specimen. Measurement

C96660 Hepatitis B Virus Core Hepatitis B Virus A measurement of the hepatitis B virus core antibody Hepatitis B Virus Core Antibody Antibody Core Antibody in a biological specimen. Measurement

C96661 Hepatitis B Virus Core IgM Hepatitis B Virus A measurement of the hepatitis B virus core IgM Hepatitis B Virus Core IgM Antibody Antibody Core IgM antibody in a biological specimen. Measurement Antibody

C74711 Hepatitis B Virus Surface Anti-HBs; A measurement of the surface antibody reaction of a Hepatitis B Surface Antibody Antibody HBsAb; Hepatitis biological specimen to the Hepatitis B virus. Measurement B Virus Surface Antibody

C64850 Hepatitis B Virus Surface HBsAg; Hepatitis A measurement of the surface antigen reaction of a Hepatitis B Virus Surface Antigen Antigen B Virus Surface biological specimen to the Hepatitis B virus. Measurement Antigen

C96662 Hepatitis B Virus e Antibody Hepatitis B Virus A measurement of the hepatitis B e antibody in a Hepatitis B Virus e Antibody e Antibody biological specimen. Measurement

C96663 Hepatitis B Virus e Antigen Hepatitis B Virus A measurement of the hepatitis B e antigen in a Hepatitis B Virus e Antigen e Antigen biological specimen. Measurement

C92535 Hepatitis C Virus Antibody Hepatitis C Virus A measurement of the antibody reaction of a Hepatitis C Antibody Measurement Antibody biological specimen to the Hepatitis C virus.

C96664 Hepatitis D Virus Antibody Hepatitis D Virus A measurement of the hepatitis D virus antibody in a Hepatitis D Virus Antibody Antibody; biological specimen. Measurement Hepatitis Delta Antibody

C96665 Hepatitis E Virus IgM Hepatitis E Virus A measurement of the hepatitis E virus IgM antibody in Hepatitis E Virus IgM Antibody Antibody IgM Antibody a biological specimen. Measurement

C92272 Hepatitis G RNA Hepatitis G RNA A measurement of the Hepatitis G RNA in a biological Hepatitis G RNA Measurement specimen.

C96697 Herpes Simplex Virus 1 IgG Herpes Simplex A measurement of the herpes simplex virus 1 IgG Herpes Simplex Virus 1 IgG Antibody Virus 1 IgG antibody in a biological specimen. Antibody Measurement Antibody; HSV-1 IgG Antibody

C98738 Herpes Simplex Virus 1 IgM Herpes Simplex A measurement of the Herpes Simplex virus 1 IgM Herpes Simplex Virus 1 IgM Antibody Virus 1 IgM antibodies in a biological specimen. Antibody Measurement Antibody

C96698 Herpes Simplex Virus 1/2 IgG Herpes Simplex A measurement of the herpes simplex virus 1 and 2 Herpes Simplex Virus 1/2 IgG Antibody Virus 1/2 IgG IgG antibody in a biological specimen. Antibody Measurement Antibody; HSV-1/2 IgG Ab

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 102 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C67154 - LBTEST - Laboratory Test Name Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C96666 Herpes Simplex Virus 1/2 IgM Herpes Simplex A measurement of the herpes simplex virus 1 and 2 Herpes Simplex Virus 1/2 IgM Antibody Virus 1/2 IgM IgM antibody in a biological specimen. Antibody Measurement Antibody; HSV-1/2 IgM Ab

C96667 Herpes Simplex Virus 2 IgG Herpes Simplex A measurement of the herpes simplex virus 2 IgG Herpes Simplex Virus 2 IgG Antibody Virus 2 IgG antibody in a biological specimen. Antibody Measurement Antibody; HSV-2 IgG Antibody

C98739 Herpes Simplex Virus 2 IgM Herpes Simplex A measurement of the Herpes Simplex virus 2 IgM Herpes Simplex Virus 2 IgM Antibody Virus 2 IgM antibodies in a biological specimen. Antibody Measurement Antibody

C81984 Heterophile Antibodies Heterophile A measurement of the heterophile antibodies in a Heterophile Antibody Measurement Antibodies biological specimen.

C96668 Hexokinase Hexokinase A measurement of the hexokinase in a biological Hexokinase Measurement specimen.

C74754 Hippuric Acid Crystals Hippuric Acid A measurement of the hippuric acid crystals present in Hippuric Acid Crystal Measurement Crystals a biological specimen.

C80189 Histamine Histamine A measurement of the histamine in a biological Histamine Measurement specimen.

C74741 Homocysteine Homocysteine A measurement of the homocysteine amino acid in a Homocysteine Acid Measurement biological specimen.

C100447 Homostat Model Assess of Homostat Model An assessment of beta-cell function and insulin Homeostatic Model Assessment of Insulin Rstn Assess of Insulin resistance based on fasting blood glucose and insulin Insulin Resistance Rstn; concentrations. Homeostatic Model Assessment of Insulin Resistance

C74863 Homovanillic Acid Homovanillic A measurement of the homovanillic acid metabolite in Homovanillic Acid Measurement Acid a biological specimen.

C74704 Howell-Jolly Bodies Howell-Jolly A measurement of the Howell-Jolly bodies (spherical, Howell-Jolly Body Measurement Bodies blue-black condensed DNA inclusions within the body of a red blood cell that appear under Wright-stain) in a biological specimen.

C98740 Human Anti-Sheep IgE Human A measurement of the human anti-sheep IgE antibodies Human Anti-Sheep IgE Antibody Antibody Anti-Sheep IgE in a biological specimen. Measurement Antibody

C98741 Human Anti-Sheep IgG Human A measurement of the human anti-sheep IgG Human Anti-Sheep IgG Antibody Antibody Anti-Sheep IgG antibodies in a biological specimen. Measurement Antibody

C98742 Human Anti-Sheep IgM Human A measurement of the human anti-sheep IgM Human Anti-Sheep IgM Antibody Antibody Anti-Sheep IgM antibodies in a biological specimen. Measurement Antibody

C74770 Hyaline Casts Hyaline Casts A measurement of the hyaline casts present in a Hyaline Cast Measurement biological specimen.

C74879 Hydrocodone Hydrocodone A measurement of the hydrocodone present in a Hydrocodone Measurement biological specimen.

C74880 Hydromorphone Hydromorphone A measurement of the hydromorphone present in a Hydromorphone Measurement biological specimen.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 103 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C67154 - LBTEST - Laboratory Test Name Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C80190 Hydroxyproline Hydroxyproline A measurement of the total hydroxyproline in a Hydroxyproline Measurement biological specimen.

C96669 Hyperchromia Hyperchromia A measurement of the prevalence of the erthrocytes Hyperchromia Measurement with an elevated hemoglobin concentration.

C74612 Hypersegmented Cells Hypersegmented A measurement of the hypersegmented (more than five Hypersegmented Neutrophil Cells lobes) neutrophils in a biological specimen. Measurement

C64802 Hypochromia Hypochromia An observation which indicates that the hemoglobin Hypochromia concentration in a red blood cell specimen has fallen below a specified level.

C96670 Immature Basophils Immature A measurement of the immature basophils in a Immature Basophil Count Basophils biological specimen.

C96671 Immature Immature A relative measurement (ratio or percentage) of Immature Basophil to Leukocyte Basophils/Leukocytes Basophils/ immature basophils to total leukocytes in a biological Ratio Measurement Leukocytes specimen.

C96672 Immature Cells Immature Cells A measurement of the total immature cells in a blood Immature Cell Count specimen.

C96673 Immature Eosinophils Immature A measurement of the immature eosinophils in a Immature Eosinophil Count Eosinophils biological specimen.

C96674 Immature Immature A relative measurement (ratio or percentage) of Immature Eosinophil to Leukocyte Eosinophils/Leukocytes Eosinophils/ immature eosinophils to total leukocytes in a Ratio Measurement Leukocytes biological specimen.

C96675 Immature Granulocytes Immature A measurement of the total immature granulocytes in a Immature Granulocyte Count Granulocytes biological specimen.

C100445 Immature Immature A relative measurement (ratio or percentage) of the Immature Granulocytes to Granulocytes/Leukocytes Granulocytes/ immature granulocytes to leukocytes in a biological Leukocytes Ratio Measurement Leukocytes specimen (for example a bone marrow specimen).

C100444 Immature Lymphocytes Immature A measurement of the immature lymphocytes in a Immature Lymphocytes Lymphocytes biological specimen. Measurement

C100443 Immature Immature A relative measurement (ratio or percentage) of the Immature Lymphocytes to Lymphocytes/Leukocytes Lymphocytes/ immature lymphocytes to leukocytes in a biological Leukocytes Ratio Measurement Leukocytes specimen.

C96676 Immature Monocytes Immature A measurement of the immature monocytes in a Immature Monocyte Count Monocytes biological specimen.

C96677 Immature Immature A relative measurement (ratio or percentage) of Immature Monocyte to Leukocyte Monocytes/Leukocytes Monocytes/ immature monocytes to total leukocytes in a Ratio Measurement Leukocytes biological specimen.

C96678 Immature Neutrophils Immature A measurement of the total immature neutrophils in a Immature Neutrophil Count Neutrophils biological specimen.

C100442 Immature Immature A relative measurement (ratio or percentage) of the Immature Neutrophils to Leukocytes Neutrophils/Leukocytes Neutrophils/ immature neutrophils to leukocytes in a biological Ratio Measurement Leukocytes specimen.

C96679 Immature Plasma Cells Immature Plasma A measurement of the immature plasma cells in a Immature Plasma Cell Count Cells biological specimen.

C96680 Immature Plasma Immature Plasma A relative measurement (ratio or percentage) of Immature Plasma Cell to Cells/Lymphocytes Cells/ immature plasma cells to total lymphocytes in a Lymphocyte Ratio Measurement Lymphocytes biological specimen.

C81969 Immunoglobulin A Immunoglobulin A measurement of the Immunoglobulin A in a Immunoglobulin A Measurement A biological specimen.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 104 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C67154 - LBTEST - Laboratory Test Name Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C98745 Immunoglobulin D Immunoglobulin A measurement of the Immunoglobulin D in a Immunoglobulin D Measurement D biological specimen.

C81970 Immunoglobulin E Immunoglobulin A measurement of the Immunoglobulin E in a Immunoglobulin E Measurement E biological specimen.

C81971 Immunoglobulin G Immunoglobulin A measurement of the Immunoglobulin G in a Immunoglobulin G Measurement G biological specimen.

C81972 Immunoglobulin M Immunoglobulin A measurement of the Immunoglobulin M in a Immunoglobulin M Measurement M biological specimen.

C82044 Indican Indican A measurement of the indican present in a biological Indican Measurement specimen.

C64483 Indirect Bilirubin Indirect Bilirubin A measurement of the unconjugated or Indirect Bilirubin Measurement non-water-soluble bilirubin in a biological specimen.

C92273 Influenza A H1N1 Viral Load Influenza A A measurement of the Influenza A H1N1 viral load in a Influenza A H1N1 Viral Load H1N1 Viral Load biological specimen. Measurement

C92274 Influenza A Viral Load Influenza A Viral A measurement of the Influenza A viral load in a Influenza A Viral Load Measurement Load biological specimen.

C82020 Inhibin A Inhibin A A measurement of the inhibin A in a biological Inhibin A Measurement specimen.

C96681 Inhibin B Inhibin B A measurement of the inhibin B in a biological Inhibin B Measurement specimen.

C74788 Insulin Insulin A measurement of the insulin in a biological specimen. Insulin Measurement

C74864 Insulin-like Growth Factor-1 Insulin-like A measurement of the insulin-like growth factor-1 in a Insulin Like Growth Factor-1 Growth Factor-1 biological specimen. Measurement

C74865 Insulin-like Growth Factor-2 Insulin-like A measurement of the insulin-like growth factor-2 in a Insulin Like Growth Factor-2 Growth Factor-2 biological specimen. Measurement

C81994 Interferon Alpha Interferon Alpha A measurement of the interferon alpha in a biological Interferon Alpha Measurement specimen.

C81995 Interferon Beta Interferon Beta A measurement of the interferon beta in a biological Interferon Beta Measurement specimen.

C81996 Interferon Gamma Interferon A measurement of the interferon gamma in a Interferon Gamma Measurement Gamma biological specimen.

C74805 Interleukin 1 Interleukin 1 A measurement of the interleukin 1 in a biological Interleukin 1 Measurement specimen.

C74806 Interleukin 10 Interleukin 10 A measurement of the interleukin 10 in a biological Interleukin 10 Measurement specimen.

C74807 Interleukin 11 Interleukin 11 A measurement of the interleukin 11 in a biological Interleukin 11 Measurement specimen.

C74808 Interleukin 12 Interleukin 12 A measurement of the interleukin 12 in a biological Interleukin 12 Measurement specimen.

C74809 Interleukin 13 Interleukin 13 A measurement of the interleukin 13 in a biological Interleukin 13 Measurement specimen.

C74810 Interleukin 14 Interleukin 14 A measurement of the interleukin 14 in a biological Interleukin 14 Measurement specimen.

C74811 Interleukin 15 Interleukin 15 A measurement of the interleukin 15 in a biological Interleukin 15 Measurement specimen.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 105 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C67154 - LBTEST - Laboratory Test Name Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C74812 Interleukin 16 Interleukin 16 A measurement of the interleukin 16 in a biological Interleukin 16 Measurement specimen.

C74813 Interleukin 17 Interleukin 17 A measurement of the interleukin 17 in a biological Interleukin 17 Measurement specimen.

C74814 Interleukin 18 Interleukin 18 A measurement of the interleukin 18 in a biological Interleukin 18 Measurement specimen.

C74815 Interleukin 19 Interleukin 19 A measurement of the interleukin 19 in a biological Interleukin 19 Measurement specimen.

C74816 Interleukin 2 Interleukin 2 A measurement of the interleukin 2 in a biological Interleukin 2 Measurement specimen.

C74817 Interleukin 20 Interleukin 20 A measurement of the interleukin 20 in a biological Interleukin 20 Measurement specimen.

C74818 Interleukin 21 Interleukin 21 A measurement of the interleukin 21 in a biological Interleukin 21 Measurement specimen.

C74819 Interleukin 22 Interleukin 22 A measurement of the interleukin 22 in a biological Interleukin 22 Measurement specimen.

C74820 Interleukin 23 Interleukin 23 A measurement of the interleukin 23 in a biological Interleukin 23 Measurement specimen.

C74821 Interleukin 24 Interleukin 24 A measurement of the interleukin 24 in a biological Interleukin 24 Measurement specimen.

C74822 Interleukin 25 Interleukin 25 A measurement of the interleukin 25 in a biological Interleukin 25 Measurement specimen.

C74823 Interleukin 26 Interleukin 26 A measurement of the interleukin 26 in a biological Interleukin 26 Measurement specimen.

C74824 Interleukin 27 Interleukin 27 A measurement of the interleukin 27 in a biological Interleukin 27 Measurement specimen.

C74825 Interleukin 28 Interleukin 28 A measurement of the interleukin 28 in a biological Interleukin 28 Measurement specimen.

C74826 Interleukin 29 Interleukin 29 A measurement of the interleukin 29 in a biological Interleukin 29 Measurement specimen.

C74827 Interleukin 3 Interleukin 3 A measurement of the interleukin 3 in a biological Interleukin 3 Measurement specimen.

C74828 Interleukin 30 Interleukin 30 A measurement of the interleukin 30 in a biological Interleukin 30 Measurement specimen.

C74829 Interleukin 31 Interleukin 31 A measurement of the interleukin 31 in a biological Interleukin 31 Measurement specimen.

C74830 Interleukin 32 Interleukin 32 A measurement of the interleukin 32 in a biological Interleukin 32 Measurement specimen.

C74831 Interleukin 33 Interleukin 33 A measurement of the interleukin 33 in a biological Interleukin 33 Measurement specimen.

C74832 Interleukin 4 Interleukin 4 A measurement of the interleukin 4 in a biological Interleukin 4 Measurement specimen.

C74833 Interleukin 5 Interleukin 5 A measurement of the interleukin 5 in a biological Interleukin 5 Measurement specimen.

C74834 Interleukin 6 Interleukin 6 A measurement of the interleukin 6 in a biological Interleukin 6 Measurement specimen.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 106 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C67154 - LBTEST - Laboratory Test Name Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C74835 Interleukin 7 Interleukin 7 A measurement of the interleukin 7 in a biological Interleukin 7 Measurement specimen.

C74836 Interleukin 8 Interleukin 8 A measurement of the interleukin 8 in a biological Interleukin 8 Measurement specimen.

C74837 Interleukin 9 Interleukin 9 A measurement of the interleukin 9 in a biological Interleukin 9 Measurement specimen.

C98748 Inulin Clearance Inulin Clearance A measurement of the volume of serum or plasma that Inulin Clearance would be cleared of inulin by excretion of urine for a specified unit of time (e.g. one minute).

C100439 Iohexol Clearance Iohexol A measurement of the volume of serum or plasma that Iohexol Clearance Clearance would be cleared of Iohexol through excretion for a specified unit of time.

C98749 Iothalamate Clearance Iothalamate A measurement of the volume of serum or plasma that Iothalamate Clearance Clearance would be cleared of iothalamate by excretion of urine for a specified unit of time (e.g. one minute).

C98750 Iothalamate Clearance Iothalamate A measurement of the volume of serum or plasma that Iothalamate Clearance Adjusted for Adjusted for BSA Clearance would be cleared of iothalamate by excretion of urine BSA Adjusted for for a specified unit of time (e.g. one minute), adjusted BSA for body size.

C74679 Iron Iron; FE A measurement of the iron in a biological specimen. Iron Measurement

C81985 Islet Cell 512 Antibody Islet Cell 512 A measurement of the islet cell 512 antibody in a Islet Cell 512 Antibody Antibody biological specimen. Measurement

C81986 Islet Cell 512 Antigen Islet Cell 512 A measurement of the islet cell 512 antigen in a Islet Cell 512 Antigen Measurement Antigen biological specimen.

C81987 Islet Neogenesis Assoc Islet Neogenesis A measurement of the islet neogenesis associated Islet Neogenesis Associated Protein Protein Antibody Assoc Protein protein antibody in a biological specimen. Antibody Measurement Antibody

C100459 Jo-1 Antibody Jo-1 Antibody A measurement of the Jo-1 antibody in a biological Jo-1 Antibody Measurement specimen.

C98730 Kappa Light Chain, Free Kappa Light A measurement of the free kappa light chain in a Free Kappa Light Chain Chain, Free biological specimen. Measurement

C98731 Kappa Lt Chain,Free/Lambda Kappa Lt A relative measurement (ratio or percentage) of the Free Kappa Light Chain to Free Lt Chain,Free Chain,Free/ free kappa light chain to the free lambda light chain in Lambda Light Chain Ratio Lambda Lt a biological specimen. Measurement Chain,Free

C64854 Ketones Ketones A measurement of the ketones in a biological Ketone Measurement specimen.

C100433 Kidney Injury Molecule-1 Kidney Injury A measurement of the kidney injury molecule-1 Kidney Injury Molecule-1 Molecule-1; (Kim-1) in a biological specimen. Measurement KIM-1; Hepatitis A Virus Cellular Receptor 1

C96682 Kurloff Cells Kurloff Cells A measurement of the large secretory Kurloff Cells Measurement granule-containing immune cells in a biological specimen taken from members of certain genera of the Caviidae family.

C74887 LDH Isoenzyme 1 LDH Isoenzyme A measurement of the lactate dehydrogenase Lactate Dehydrogenase Isoenzyme 1 1 isoenzyme 1 in a biological specimen. Measurement

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 107 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C67154 - LBTEST - Laboratory Test Name Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C79451 LDH Isoenzyme 1/LDH LDH Isoenzyme A relative measurement (ratio or percentage) of the LDH Isoenzyme 1 to LDH Ratio 1/LDH lactate dehydrogenase isoenzyme 1 to total lactate Measurement dehydrogenase in a biological specimen.

C74888 LDH Isoenzyme 2 LDH Isoenzyme A measurement of the lactate dehydrogenase Lactate Dehydrogenase Isoenzyme 2 2 isoenzyme 2 in a biological specimen. Measurement

C79452 LDH Isoenzyme 2/LDH LDH Isoenzyme A relative measurement (ratio or percentage) of the LDH Isoenzyme 2 to LDH Ratio 2/LDH lactate dehydrogenase isoenzyme 2 to total lactate Measurement dehydrogenase in a biological specimen.

C74889 LDH Isoenzyme 3 LDH Isoenzyme A measurement of the lactate dehydrogenase Lactate Dehydrogenase Isoenzyme 3 3 isoenzyme 3 in a biological specimen. Measurement

C79453 LDH Isoenzyme 3/LDH LDH Isoenzyme A relative measurement (ratio or percentage) of the LDH Isoenzyme 3 to LDH Ratio 3/LDH lactate dehydrogenase isoenzyme 3 to total lactate Measurement dehydrogenase in a biological specimen.

C74890 LDH Isoenzyme 4 LDH Isoenzyme A measurement of the lactate dehydrogenase Lactate Dehydrogenase Isoenzyme 4 4 isoenzyme 4 in a biological specimen. Measurement

C79454 LDH Isoenzyme 4/LDH LDH Isoenzyme A relative measurement (ratio or percentage) of the LDH Isoenzyme 4 to LDH Ratio 4/LDH lactate dehydrogenase isoenzyme 4 to total lactate Measurement dehydrogenase in a biological specimen.

C74891 LDH Isoenzyme 5 LDH Isoenzyme A measurement of the lactate dehydrogenase Lactate Dehydrogenase Isoenzyme 5 5 isoenzyme 5 in a biological specimen. Measurement

C79455 LDH Isoenzyme 5/LDH LDH Isoenzyme A relative measurement (ratio or percentage) of the LDH Isoenzyme 5 to LDH Ratio 5/LDH lactate dehydrogenase isoenzyme 5 to total lactate Measurement dehydrogenase in a biological specimen.

C61042 LDL Cholesterol LDL Cholesterol A measurement of the low density lipoprotein Serum LDL Cholesterol cholesterol in a biological specimen. Measurement

C64855 Lactate Dehydrogenase Lactate A measurement of the lactate dehydrogenase in a Lactate Dehydrogenase Dehydrogenase biological specimen. Measurement

C79449 Lactate Lactate A relative measurement (ratio or percentage) of the Lactate Dehydrogenase to Creatinine Dehydrogenase/Creatinine Dehydrogenase/ lactate dehydrogenase to creatinine in a biological Ratio Measurement Creatinine specimen.

C79450 Lactic Acid Lactic Acid; A measurement of the lactic acid in a biological Lactic Acid Measurement 2-hydroxypropan specimen. oic acid; Lactate

C82021 Lactoferrin Lactoferrin; A measurement of the lactoferrin in a biological Lactoferrin Measurement Lactotransferrin specimen.

C98732 Lambda Light Chain, Free Lambda Light A measurement of the free lambda light chain in a Free Lambda Light Chain Chain, Free biological specimen. Measurement

C74729 Large Platelets Large Platelets A measurement of the large (between 4 um and 7um in Large Platelet Count diameter) platelets in a biological specimen.

C74659 Large Unstained Cells Large Unstained A measurement of the large, peroxidase-negative cells Large Unstained Cell Count Cells which cannot be further characterized (i.e. as large lymphocytes, virocytes, or stem cells) present in a biological specimen.

C79467 Large Unstained Large Unstained A relative measure (ratio or percentage) of the large Large Unstained Cells to Leukocytes Cells/Leukocytes Cells/ unstained cells to leukocytes in a biological specimen. Ratio Measurement Leukocytes

C92275 Legionella pneumophila Legionella A measurement of the Legionella pneumophila antigen Legionella pneumophila Antigen Antigen pneumophila in a biological specimen. Measurement Antigen

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 108 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C67154 - LBTEST - Laboratory Test Name Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C92276 Legionella pneumophila IgG Legionella A measurement of the Legionella pneumophila IgG Legionella pneumophila IgG Antibody pneumophila IgG antibody in a biological specimen. Antibody Measurement Antibody

C92277 Legionella pneumophila IgG Legionella A measurement of the Legionella pneumophila IgG and Legionella pneumophila IgG IgM IgM Antibody pneumophila IgG IgM in a biological specimen. Antibody Measurement IgM Antibody

C92278 Legionella pneumophila IgM Legionella A measurement of the Legionella pneumophila IgM Legionella pneumophila IgM Antibody pneumophila IgM antibody in a biological specimen. Antibody Measurement Antibody

C74866 Leptin Leptin A measurement of the leptin hormone in a biological Leptin Measurement specimen.

C74680 Leucine Crystals Leucine Crystals A measurement of the leucine crystals present in a Leucine Crystal Measurement biological specimen.

C74630 Leukemic Blasts Leukemic Blasts; A measurement of the leukemic blasts (lymphoblasts Leukemic Blast Count Leukemic that remain in an immature state even when outside the Lymphoblasts; bone marrow) in a biological specimen. Immunoblastic Lymphocytes

C74641 Leukemic Leukemic A relative measurement (ratio or percentage) of the Leukemic Blast to Lymphocyte Blasts/Lymphocytes Blasts/ leukemic blasts (immature lymphoblasts) to mature Ratio Measurement Lymphocytes lymphocytes in a biological specimen.

C92246 Leukocyte Cell Clumps Leukocyte Cell A measurement of white blood cell clumps in a Leukocyte Cell Clumps Clumps; White biological specimen. Measurement Blood Cell Clumps; WBC Clumps

C92297 Leukocyte Cell Morphology Leukocyte Cell An examination or assessment of the form and Leukocyte Cell Morphology Morphology; structure of white blood cells. White Blood Cell Morphology; WBC Morphology

C64856 Leukocyte Esterase Leukocyte A measurement of the enzyme which indicates the Leukocyte Esterase Measurement Esterase presence of white blood cells in a biological specimen.

C51948 Leukocytes Leukocytes; A measurement of the leukocytes in a biological Leukocyte Count White Blood specimen. Cells

C82022 Lipoprotein-a Lipoprotein-a A measurement of the lipoprotein-a in a biological Lipoprotein a Measurement specimen.

C96683 Liver Kidney Microsomal Liver Kidney A measurement of the liver kidney microsomal type 1 Liver Kidney Microsomal Type 1 Type 1 Antibody Microsomal antibody in a biological specimen. Antibody Measurement Type 1 Antibody; LKM-1

C100456 Liver Kidney Microsomal Liver Kidney A measurement of the liver kidney microsomal type 1 Liver Kidney Microsomal Type 1 Type 1 IgA Ab Microsomal IgA antibodies in a biological specimen. IgA Antibody Measurement Type 1 IgA Ab

C100454 Liver Kidney Microsomal Liver Kidney A measurement of the liver kidney microsomal type 1 Liver Kidney Microsomal Type 1 Type 1 IgG Ab Microsomal IgG antibodies in a biological specimen. IgG Antibody Measurement Type 1 IgG Ab

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 109 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C67154 - LBTEST - Laboratory Test Name Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C100455 Liver Kidney Microsomal Liver Kidney A measurement of the liver kidney microsomal type 1 Liver Kidney Microsomal Type 1 Type 1 IgM Ab Microsomal IgM antibodies in a biological specimen. IgM Antibody Measurement Type 1 IgM Ab

C74790 Luteinizing Hormone Luteinizing A measurement of the luteinizing hormone in a Luteinizing Hormone Measurement Hormone biological specimen.

C51949 Lymphocytes Lymphocytes A measurement of the lymphocytes in a biological Lymphocyte Count specimen.

C64818 Lymphocytes Atypical Lymphocytes A measurement of the atypical lymphocytes in a Atypical Lymphocyte Count Atypical biological specimen.

C64819 Lymphocytes Lymphocytes A relative measurement (ratio or percentage) of the Atypical Lymphocyte To Leukocyte Atypical/Leukocytes Atypical/ atypical lymphocytes to leukocytes in a biological Ratio Leukocytes specimen.

C64820 Lymphocytes/Leukocytes Lymphocytes/ A relative measurement (ratio or percentage) of the Lymphocyte To Leukocyte Ratio Leukocytes lymphocytes to leukocytes in a biological specimen.

C98751 Lymphocytes/Total Cells Lymphocytes/ A relative measurement (ratio or percentage) of the Lymphocyte to Total Cell Ratio Total Cells lymphocytes to total cells in a biological specimen Measurement (for example a bone marrow specimen).

C74613 Lymphoma Cells Lymphoma Cells A measurement of the malignant lymphocytes in a Lymphoma Cell Count biological specimen.

C74910 Lymphoma Lymphoma A relative measurement (ratio or percentage) of the Lymphoma Cell to Lymphocyte Cells/Lymphocytes Cells/ malignant lymphocytes to all lymphocytes in a Ratio Measurement Lymphocytes biological specimen.

C81955 Lymphotactin Lymphotactin; A measurement of the lymphotactin in a biological Lymphotactin Measurement Chemokine specimen. Ligand 1

C92241 M. tuberculosis IFN Gamma Mycobacterium A measurement of the amount of interferon gamma Mycobacterium tuberculosis Response tuberculosis IFN that is released when Mycobacterium tuberculosis Interferon Gamma Response Gamma antigen is incubated with a biological specimen, Response usually blood. Increased amounts of interferon gamma suggests a prior or existing M. tuberculosis infection.

C64821 Macrocytes Macrocytes A measurement of the macrocytes in a biological Macrocyte Count specimen.

C80191 Macrophage Colony Macrophage A measurement of the macrophage colony stimulating Macrophage Colony Stimulating Stimulating Factor Colony factor in a biological specimen. Factor Measurement Stimulating Factor

C82023 Macrophage Inflammatory Macrophage A measurement of the macrophage inflammatory Macrophage Inflammatory Protein 1 Protein 1 Alpha Inflammatory protein 1 alpha in a biological specimen. Alpha Measurement Protein 1 Alpha; Chemokine Ligand 3

C82024 Macrophage Inflammatory Macrophage A measurement of the macrophage inflammatory Macrophage Inflammatory Protein 1 Protein 1 Beta Inflammatory protein 1 beta in a biological specimen. Beta Measurement Protein 1 Beta; Chemokine Ligand 4

C81956 Macrophage-Derived Macrophage-Der A measurement of the macrophage-derived chemokine Macrophage-Derived Chemokine Chemokine ived Chemokine; in a biological specimen. Measurement Chemokine Ligand 22

C64840 Magnesium Magnesium A measurement of the magnesium in a biological Magnesium Measurement specimen.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 110 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C67154 - LBTEST - Laboratory Test Name Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C79456 Magnesium/Creatinine Magnesium/ A relative measurement (ratio or percentage) of the Magnesium to Creatinine Ratio Creatinine magnesium to creatinine in a biological specimen. Measurement

C74660 Malignant Cells, NOS Malignant Cells, A measurement of the malignant cells of all types in a Malignant Cell Count NOS biological specimen.

C74643 Malignant Cells, NOS/Blood Malignant Cells, A relative measurement (ratio or percentage) of the Malignant Cell to Blood Cell Ratio Cells NOS/Blood malignant cells of all types to all blood cells in a Measurement Cells biological specimen.

C80192 Matrix Metalloproteinase 1 Matrix A measurement of the matrix metalloproteinase 1 in a Matrix Metalloproteinase 1 Metalloproteinas biological specimen. Measurement e 1; Interstitial Collagenase

C80193 Matrix Metalloproteinase 2 Matrix A measurement of the matrix metalloproteinase 2 in a Matrix Metalloproteinase 2 Metalloproteinas biological specimen. Measurement e 2; Gelatinase A

C80194 Matrix Metalloproteinase 3 Matrix A measurement of the matrix metalloproteinase 3 in a Matrix Metalloproteinase 3 Metalloproteinas biological specimen. Measurement e 3; Stromelysin 1

C80195 Matrix Metalloproteinase 7 Matrix A measurement of the matrix metalloproteinase 7 in a Matrix Metalloproteinase 7 Metalloproteinas biological specimen. Measurement e 7; Matrilysin

C80196 Matrix Metalloproteinase 8 Matrix A measurement of the matrix metalloproteinase 8 in a Matrix Metalloproteinase 8 Metalloproteinas biological specimen. Measurement e 8; Neutrophil Collagenase

C80197 Matrix Metalloproteinase 9 Matrix A measurement of the matrix metalloproteinase 9 in a Matrix Metalloproteinase 9 Metalloproteinas biological specimen. Measurement e 9; Gelatinase B

C74661 Mature Plasma Cells Mature Plasma A measurement of the mature plasma cells Mature Plasma Cell Count Cells; (plasmacytes) in a biological specimen. Plasmacytes

C74911 Mature Plasma Mature Plasma A relative measurement (ratio or percentage) of the Mature Plasma Cell to Lymphocyte Cells/Lymphocytes Cells/ mature plasma cells (plasmacytes) to all lymphocytes Ratio Measurement Lymphocytes in a biological specimen.

C74614 May-Hegglin Anomaly May-Hegglin A measurement of the May-Hegglin anomaly in a May-Hegglin Anomaly Measurement Anomaly blood sample. This anomaly is characterized by large, misshapen platelets and the presence of Dohle bodies in leukocytes.

C96686 Mean Platelet Component Mean Platelet A measurement of the mean platelet component Mean Platelet Component Component (platelet activity) in a blood specimen. Measurement

C74730 Mean Platelet Volume Mean Platelet A measurement of the average size of the platelets Mean Platelet Volume Measurement Volume present in a blood sample.

C98752 Megakaryoblasts Megakaryoblasts A measurement of the megakaryoblasts in a biological Megakaryoblast Cell Count specimen.

C98753 Megakaryoblasts/Total Cells Megakaryoblasts A relative measurement (ratio or percentage) of the Megakaryoblast to Total Cell Ratio /Total Cells megakaryoblasts to total cells in a biological specimen Measurement (for example a bone marrow specimen).

C96688 Megakaryocytes Megakaryocytes A measurement of the megakaryocytes per unit of a Megakaryocyte Count biological specimen.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 111 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C67154 - LBTEST - Laboratory Test Name Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C98867 Megakaryocytes/Total Cells Megakaryocytes/ A relative measurement (ratio or percentage) of the Megakaryocyte to Total CellRatio Total Cells megakaryocytes to total cells in a biological specimen Measurement (for example a bone marrow specimen).

C74867 Melatonin Melatonin A measurement of the melatonin hormone in a Melatonin Measurement biological specimen.

C74615 Metamyelocytes Metamyelocytes A measurement of the metamyelocytes (small, Metamyelocyte Count myelocytic neutrophils with an indented nucleus) in a biological specimen.

C74645 Metamyelocytes/Leukocytes Metamyelocytes/ A relative measurement (ratio or percentage) of the Metamyelocyte to Leukocyte Ratio Leukocytes metamyelocytes (small, myelocytic neutrophils with Measurement an indented nucleus) to all leukocytes in a biological specimen.

C98754 Metamyelocytes/Total Cells Metamyelocytes/ A relative measurement (ratio or percentage ) of the Metamyelocyte to Total Cell Ratio Total Cells metamyelocytes (small, myelocytic neutrophils with Measurement an indented nucleus) to total cells in a biological specimen (for example a bone marrow specimen).

C74881 Methadone Methadone A measurement of the methadone present in a Methadone Measurement biological specimen.

C74882 Methaqualone Methaqualone A measurement of the methaqualone present in a Methaqualone Measurement biological specimen.

C96689 Methemoglobin Methemoglobin A measurement of the methemoglobin in a biological Methemoglobin Measurement specimen.

C96690 Methylmalonic Acid Methylmalonic A measurement of the methylmalonic acid in a Methylmalonic Acid Measurement Acid biological specimen.

C64822 Microcytes Microcytes A measurement of the microcytes in a biological Microcyte Count specimen.

C74771 Mixed Casts Mixed Casts A measurement of the mixed (the cast contains a Mixed Cast Count mixture of cell types) casts present in a biological specimen.

C74631 Monoblasts Monoblasts A measurement of the monoblast cells in a biological Monoblast Count specimen.

C74646 Monoblasts/Leukocytes Monoblasts/ A relative measurement (ratio or percentage) of the Monoblast to Leukocyte Ratio Leukocytes monoblasts to leukocytes in a biological specimen. Measurement

C92291 Monoclonal Protein Monoclonal A measurement of homogenous immunoglobulin Monoclonal Protein Measurement Immunoglobulin resulting from the proliferation of a single clone of Protein; plasma cells in a biological specimen. Paraprotein

C82025 Monocyte Chemotactic Monocyte A measurement of the monocyte chemotactic protein Monocyte Chemotactic Protein 1 Protein 1 Chemotactic 1 in a biological specimen. Measurement Protein 1

C64823 Monocytes Monocytes A measurement of the monocytes in a biological Monocyte Count specimen.

C64824 Monocytes/Leukocytes Monocytes/ A relative measurement (ratio or percentage) of the Monocyte To Leukocyte Ratio Leukocytes monocytes to leukocytes in a biological specimen.

C98872 Monocytes/Total Cells Monocytes/Total A relative measurement (ratio or percentage) of the Monocytes to Total Cells monocytes to total cells in a biological specimen (for CellRatioMeasurement example a bone marrow specimen).

C74681 Monosodium Urate Crystals Monosodium A measurement of the monosodium urate crystals Monosodium Urate Crystal Urate Crystals present in a biological specimen. Measurement

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 112 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C67154 - LBTEST - Laboratory Test Name Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C74883 Morphine Morphine A measurement of the morphine present in a biological Morphine Measurement specimen.

C79457 Mu Glutathione-S-Transferase Mu A measurement of the mu form of glutathione Mu Glutathione-S-Transferase Glutathione-S-Tr S-transferase in a biological specimen. Measurement ansferase

C79458 Mu Mu A relative measurement (ratio or percentage) of the Mu Glutathione-S-Transferase to Glutathione-S-Transferase/ Glutathione-S-Tr mu gamma glutamyl transpeptidase to creatinine in a Creatinine Ratio Measurement Creatinine ansferase/ biological specimen. Creatinine

C74721 Mucous Threads Mucous Threads A measurement of the mucous threads present in a Mucous Thread Measurement biological specimen.

C92279 Mycobacterium tuberculosis Mycobacterium A measurement of the Mycobacterium tuberculosis Mycobacterium tuberculosis Nucleic Nucleic Acid tuberculosis nucleic acid in a biological specimen. Acid Measurement Nucleic Acid

C74632 Myeloblasts Myeloblasts A measurement of the myeloblast cells in a biological Myeloblast Count specimen.

C64825 Myeloblasts/Leukocytes Myeloblasts/ A relative measure (ratio or percentage) of the Myeloblast To Leukocyte Ratio Leukocytes myeloblasts to leukocytes in a biological specimen.

C98761 Myeloblasts/Total Cells Myeloblasts/ A relative measurement (ratio or percentage) of the Myeloblast to Total Cell Ratio Total Cells myeloblasts to total cells in a biological specimen (for Measurement example a bone marrow specimen).

C74662 Myelocytes Myelocytes A measurement of the myelocytes in a biological Myelocyte Count specimen.

C64826 Myelocytes/Leukocytes Myelocytes/ A relative measurement (ratio or percentage) of the Myelocyte To Leukocyte Ratio Leukocytes myelocytes to leukocytes in a biological specimen.

C98868 Myelocytes/Total Cells Myelocytes/ A relative measurement (ratio or percentage) of the Myelocyte to Total CellRatio Total Cells myelocytes to total cells in a biological specimen (for Measurement example a bone marrow specimen).

C92242 Myeloid/Erythroid Ratio Myeloid/ A relative measurement (ratio or percentage) of Myeloid to Erythroid Ratio Erythroid Ratio myeloid progenitor cells to erythrocyte precursor Measurement cells in a biological specimen.

C80198 Myeloperoxidase Myeloperoxidase A measurement of the myeloperoxidase in a biological Myeloperoxidase Measurement specimen.

C92280 Myeloperoxidase Antibody Myeloperoxidase A measurement of the myeloperoxidase antibody in a Myeloperoxidase Antibody Antibody biological specimen. Measurement

C79436 Myoglobin Myoglobin A measurement of myoglobin in a biological Myoglobin Measurement specimen.

C79459 N-Acetyl Glucosamide N-Acetyl A measurement of N-acetyl glucosamide in a N-Acetyl Glucosamide Measurement Glucosamide; biological specimen. N-Acetyl Glucosamine

C79460 N-Acetyl N-Acetyl A relative measurement (ratio or percentage) of the N-Acetyl Glucosamide to Creatinine Glucosamide/Creatinine Glucosamide/ N-acetyl glucosamide to creatinine in a biological Ratio Measurement Creatinine specimen.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 113 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C67154 - LBTEST - Laboratory Test Name Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C96610 N-Terminal ProB-type N-Terminal A measurement of the N-terminal proB-type N-Terminal ProB-type Natriuretic Natriuretic Peptide ProB-type natriuretic peptide in a biological specimen. Peptide Measurement Natriuretic Peptide; NT proBNP II; N-terminal pro-Brain Natriuretic Peptide

C74743 N-telopeptide N-telopeptide A measurement of the N-telopeptide in a biological N-telopeptide Measurement specimen.

C98762 Natural Killer Cells Natural Killer A measurement of the total natural killer cells in a Natural Killer Cell Count Cells biological specimen.

C92298 Neisseria gonorrhoeae Neisseria Examination of a biological specimen to detect the Neisseria gonorrhoeae Screening Screening gonorrhoeae presence of Neisseria gonorrhoeae. Screening

C80199 Neopterin Neopterin A measurement of the neopterin in a biological Neopterin Measurement specimen.

C74892 Neuropeptide Y Neuropeptide Y A measurement of the neuropeptide Y in a biological Neuropeptide Y Measurement specimen.

C82026 Neutrophil Elastase Neutrophil A measurement of the neutrophil elastase in a Neutrophil Elastase Measurement Elastase biological specimen.

C82027 Neutrophil Elastase, Neutrophil A measurement of the polymorphonuclear neutrophil Polymorphonuclear Neutrophil Polymorphonuclear Elastase, elastase in a biological specimen. Elastase Measurement Polymorphonucl ear

C84822 Neutrophilic Metamyelocytes Neutrophilic A measurement of the neutrophilic metamyelocytes in Neutrophilic Metamyelocyte Count Metamyelocytes a biological specimen.

C84823 Neutrophilic Myelocytes Neutrophilic A measurement of the neutrophilic myelocytes in a Neutrophilic Myelocyte Count Myelocytes biological specimen.

C63321 Neutrophils Neutrophils A measurement of the neutrophils in a biological Absolute Neutrophil Count specimen.

C64830 Neutrophils Band Form Neutrophils Band A measurement of the banded neutrophils in a Neutrophil Band Form Count Form biological specimen.

C64831 Neutrophils Band Neutrophils Band A relative measurement (ratio or percentage) of the Neutrophil Band Form To Leukocyte Form/Leukocytes Form/ banded neutrophils to leukocytes in a biological Ratio Leukocytes specimen.

C81997 Neutrophils, Segmented Neutrophils, A measurement of the segmented neutrophils in a Segmented Neutrophil Count Segmented biological specimen.

C82045 Neutrophils, Neutrophils, A relative measurement (ratio or percentage) of Segmented Neutrophil to Leukocyte Segmented/Leukocytes Segmented/ segmented neutrophils to leukocytes in a biological Ratio Measurement Leukocytes specimen.

C64827 Neutrophils/Leukocytes Neutrophils/ A relative measurement (ratio or percentage) of the Neutrophil To Leukocyte Ratio Leukocytes neutrophils to leukocytes in a biological specimen.

C98763 Neutrophils/Total Cells Neutrophils/ A relative measurement (ratio or percentage) of the Neutrophil to Total Cell Ratio Total Cells neutrophils to total cells in a biological specimen (for Measurement example a bone marrow specimen).

C74899 Niacin Niacin; Vitamin A measurement of the niacin in a biological specimen. Vitamin B3 Measurement B3

C64810 Nitrite Nitrite A measurement of the nitrite in a urine specimen. Nitrite Measurement

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 114 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C67154 - LBTEST - Laboratory Test Name Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C84811 Non-Phosphorylated Tau Non-Phosphoryl A measurement of the non-phosphorylated Tau protein Nonphosphorylated Tau Protein Protein ated Tau Protein in a biological specimen. Measurement

C100434 Non-Prostatic Acid Non-Prostatic A measurement of the non-prostatic acid phosphatase Non-Prostatic Acid Phosphatase Phosphatase Acid in a biological specimen. Measurement Phosphatase

C74868 Norepinephrine Noradrenaline; A measurement of the norepinephrine hormone in a Noradrenaline Measurement Norepinephrine biological specimen.

C98764 Normoblasts/Total Cells Normoblasts/ A relative measurement (ratio or percentage) of the Normoblast to Total Cell Ratio Total Cells normoblasts to total cells in a biological specimen Measurement (for example a bone marrow specimen).

C74705 Nucleated Erythrocytes Nucleated A measurement of the nucleated erythrocytes (large, Nucleated Red Blood Cell Count Erythrocytes; immature nucleated erythrocytes) in a biological Nucleated Red specimen. Blood Cells

C74647 Nucleated Nucleated A relative measurement (ratio or percentage) of the Nucleated Red Blood Cell to Erythrocytes/Erythrocytes Erythrocytes/ nucleated erythrocytes (large, immature nucleated Erythrocyte Ratio Measurement Erythrocytes; erythrocytes) to all erythrocytes in a biological Nucleated Red specimen. Blood Cells/ Erythrocytes

C82046 Nucleated Nucleated A relative measurement (ratio or percentage) of Nucleated Erythrocyte to Leukocyte Erythrocytes/Leukocytes Erythrocytes/ nucleated erythrocytes to leukocytes in a biological Ratio Measurement Leukocytes specimen.

C74686 Occult Blood Occult Blood A measurement of the blood in body products such as a Occult Blood Measurement stool sample, not detectable on gross examination.

C74796 Opiate Opiate A measurement of any opiate class drug present in a Opiate Measurement biological specimen.

C74801 Osmolality Osmolality A measurement of the osmoles of solute per unit of Osmolality Measurement biological specimen.

C74802 Osmolarity Osmolarity A measurement of the osmoles of solute per liter of Osmolarity Measurement solution.

C74744 Osteocalcin Osteocalcin A measurement of the osteocalcin in a biological Osteocalcin Measurement specimen.

C100452 Ova and Parasite Ova and Parasite A measurement of the parasites and ova in a biological Ova and Parasite Measurement specimen.

C92250 Oxalate Oxalate; A measurement of the oxalate in a biological Oxalate Measurement Ethanedioate specimen.

C74884 Oxycodone Oxycodone; A measurement of the oxycodone present in a Oxycodone Measurement Oxycontin biological specimen.

C96614 Oxygen Capacity Oxygen Capacity A measurement of the maximum amount of oxygen Oxygen Capacity Measurement that can be combined chemically with hemoglobin in a volume of blood.

C68032 Oxygen Saturation Oxygen A measurement of the oxygen-hemoglobin saturation Oxygen Saturation Measurement Saturation of a volume of blood.

C96616 Oxyhemoglobin Oxyhemoglobin A measurement of the oxyhemoglobin in a biological Oxyhemoglobin Measurement specimen.

C74869 Oxytocin Oxytocin; A measurement of the oxytocin hormone in a Oxytocin Measurement Oxytoxin biological specimen.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 115 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C67154 - LBTEST - Laboratory Test Name Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C82028 Pancreatic Elastase 1 Pancreatic A measurement of the pancreatic elastase 1 in a Pancreatic Elastase Measurement Elastase 1 biological specimen.

C82029 Pancreatic Elastase 1, Pancreatic A measurement of the polymorphonuclear pancreatic Polymorphonuclear Pancreatic Polymorphonuclear Elastase 1, elastase 1 in a biological specimen. Elastase Measurement Polymorphonucl ear

C80201 Pancreatic Polypeptide Pancreatic A measurement of the pancreatic polypeptide in a Pancreatic Polypeptide Polypeptide biological specimen. Measurement

C74616 Pappenheimer Bodies Pappenheimer A measurement of the cells containing Pappenheimer Pappenheimer Body Count Bodies Bodies (violet or blue staining ferritin granules usually found along the periphery of the red blood cells) in a biological specimen.

C81964 Parathyroid Hormone, Parathyroid A measurement of the C-terminal fragment of C-Terminal Parathyroid Hormone C-Terminal Hormone, parathyroid hormone in a biological specimen. Measurement C-Terminal

C74784 Parathyroid Hormone, Parathyroid A measurement of the fragmented parathyroid Fragmented Parathyroid Hormone Fragmented Hormone, hormone in a biological specimen. Measurement Fragmented

C74789 Parathyroid Hormone, Intact Parathyroid A measurement of the intact parathyroid hormone in a Intact Parathyroid Hormone Hormone, Intact biological specimen. Measurement

C81965 Parathyroid Hormone, Parathyroid A measurement of the mid-molecule fragment of Mid-Molecule Parathyroid Hormone Mid-Molecule Hormone, parathyroid hormone in a biological specimen. Measurement Mid-Molecule

C81966 Parathyroid Hormone, Parathyroid A measurement of the N-terminal fragment of N-Terminal Parathyroid Hormone N-Terminal Hormone, parathyroid hormone in a biological specimen. Measurement N-Terminal

C82625 Partial Pressure Carbon Partial Pressure A measurement of the pressure of carbon dioxide in a Partial Pressure of Carbon Dioxide Dioxide Carbon Dioxide biological specimen. Measurement

C71251 Partial Pressure Oxygen Partial Pressure A measurement of the pressure of oxygen in a Partial Pressure of Oxygen Oxygen biological specimen. Measurement

C96617 Parvovirus B19 IgG Antibody Parvovirus B19 A measurement of the Parvovirus B19 IgG antibody in Parvovirus B19 IgG Antibody IgG Antibody a biological specimen. Measurement

C96618 Parvovirus B19 IgM Antibody Parvovirus B19 A measurement of the Parvovirus B19 IgM antibody in Parvovirus B19 IgM Antibody IgM Antibody a biological specimen. Measurement

C74617 Pelger Huet Anomaly Pelger Huet A measurement of the Pelger Huet Anomaly (nuclei of Pelger Huet Anomaly Measurement Anomaly neutrophils and eosinophils appear rod-like, spherical or dumbbell shaped) in a biological specimen.

C81988 Pemphigoid Antibodies Pemphigoid A measurement of the pemphigoid antibodies in a Pemphigoid Antibody Measurement Antibodies biological specimen.

C100122 Pepsinogen Pepsinogen A measurement of the pepsinogen in a biological Pepsinogen Measurement specimen.

C100469 Pepsinogen A Pepsinogen A; A measurement of the pepsinogen A in a biological Pepsinogen A Measurement PGA specimen.

C100470 Pepsinogen C Pepsinogen C; A measurement of the pepsinogen C in a biological Pepsinogen C Measurement PGC specimen.

C100467 Pepsinogen I Pepsinogen I; A measurement of the pepsinogen I in a biological Pepsinogen I Measurement PGI specimen.

C100468 Pepsinogen II Pepsinogen II; A measurement of the pepsinogen II in a biological Pepsinogen II Measurement PGII specimen.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 116 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C67154 - LBTEST - Laboratory Test Name Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C80202 Peptide YY Peptide YY; A measurement of the peptide YY in a biological Peptide YY Measurement Peptide Tyrosine specimen. Tyrosine

C74694 Phencyclidine Phencyclidine; A measurement of the phencyclidine present in a Phencyclidine Measurement Phenylcyclohexy biological specimen. lpiperidine

C74695 Phenothiazine Phenothiazine; A measurement of the phenothiazine present in a Phenothiazine Measurement Dibenzothiazine biological specimen.

C64857 Phosphate Phosphate; A measurement of the phosphate in a biological Phosphate Measurement Phosphorus; specimen. Inorganic Phosphate

C79461 Phosphate/Creatinine Phosphate/ A relative measurement (ratio or percentage) of the Phosphate to Creatinine Ratio Creatinine phosphate to creatinine in a biological specimen. Measurement

C96623 Phospholipid Phospholipid A measurement of the phospholipids in a biological Phospholipid Measurement specimen.

C84812 Phosphorylated Tau Protein Phosphorylated A measurement of the phosphorylated Tau protein in a Phosphorylated Tau Protein Tau Protein biological specimen. Measurement

C98869 Plasma Cells/Total Cells Plasma A relative measurement (ratio or percentage) of the Plasma Cell to Total CellRatio Cells/Total Cells mature plasma cells (plasmacytes) to total cells in a Measurement biological specimen (for example a bone marrow specimen).

C74618 Plasmacytoid Lymphocytes Plasmacytoid A measurement of the plasmacytoid lymphocytes Plasmacytoid Lymphocyte Count Lymphocytes; (lymphocytes with peripherally clumped chromatin and Plymphocytes often deep blue cytoplasm, and that appear similar to plasma cells) in a biological specimen.

C74648 Plasmacytoid Plasmacytoid A relative measurement (ratio or percentage) of the Plasmacytoid Lymphocyte to Lymphocytes/Lymphocytes Lymphocytes/ plasmacytoid lymphocytes (lymphocytes with Lymphocyte Ratio Measurement Lymphocytes peripherally clumped chromatin and often deep blue cytoplasm, and that appear similar to plasma cells) to all lymphocytes in a biological specimen.

C82030 Plasminogen Activator Plasminogen A measurement of the plasminogen activator Plasminogen Activator Inhibitor-1 Inhibitor-1 Activator inhibitor-1 in a biological specimen. Measurement Inhibitor-1

C81989 Plasminogen Activator Plasminogen A measurement of the plasminogen activator Plasminogen Activator Inhibitor-1 Inhibitor-1 AG Activator inhibitor-1 antigen in a biological specimen. Antigen Measurement Inhibitor-1 AG

C100453 Plasmodium Plasmodium Examination of a biological specimen to detect the Plasmodium Measurement presence of any protozoan belonging to the Plasmodium genus.

C96624 Platelet Clumps Platelet Clumps; A measurement of the platelet clumps in a biological Platelet Clumps Count PLT Clumps specimen.

C81962 Platelet Distribution Width Platelet A measurement of the range of platelet sizes in a Platelet Distribution Width Distribution biological specimen. Width

C100424 Platelet Hematocrit Platelet A relative measurement (ratio or percentage) of the Platelet Hematocrit Measurement Hematocrit; proportion of the volume of blood taken up by Thrombocytocrit platelets.

C51951 Platelets Platelets A measurement of the platelets in a biological Platelet Count specimen.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 117 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C67154 - LBTEST - Laboratory Test Name Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C79602 Poikilocytes Poikilocytes A measurement of the odd-shaped erythrocytes in a Poikilocyte Measurement whole blood specimen.

C74649 Poikilocytes/Erythrocytes Poikilocytes/ A relative measurement (ratio or percentage) of the Poikilocyte to Erythrocyte Ratio Erythrocytes poikilocytes, or irregularly shaped erythrocytes, to all Measurement erythrocytes in a biological specimen.

C64803 Polychromasia Polychromasia A measurement of the blue-staining characteristic of Polychromasia newly generated erythrocytes.

C64853 Potassium Potassium A measurement of the potassium in a biological Potassium Measurement specimen.

C79462 Potassium/Creatinine Potassium/ A relative measurement (ratio or percentage) of the Potassium to Creatinine Ratio Creatinine potassium to creatinine in a biological specimen. Measurement

C100435 Prealbumin Prealbumin A measurement of the prealbumin in a biological Prealbumin Measurement specimen.

C74619 Precursor Plasma Cells Precursor A measurement of the precursor (blast stage) plasma Precursor Plasma Cell Count Plasma Cells; cells (antibody secreting cells derived from B cells via Plasmablast antigen stimulation) in a biological specimen.

C74650 Precursor Plasma Precursor A relative measurement (ratio or percentage) of the Precursor Plasma Cell to Cells/Lymphocytes Plasma precursor (blast stage) plasma cells (antibody Lymphocyte Ratio Measurement Cells/ secreting cells derived from B cells via antigen Lymphocytes stimulation) to all lymphocytes in a biological specimen.

C82031 Pregnancy-Associated Plasma Pregnancy-Assoc A measurement of the pregnancy-associated plasma Pregnancy-Associated Plasma Protein-A iated Plasma protein-A in a biological specimen. Protein-A Measurement Protein-A

C82032 ProB-type Natriuretic Peptide ProB-type A measurement of the proB-type natriuretic peptide in ProB-Type Natriuretic Peptide Natriuretic a biological specimen. Measurement Peptide; proBNP; Pro-Brain Natriuretic Peptide

C96625 Procollagen 1 N-Terminal Procollagen 1 A measurement of the procollagen 1 N-terminal Procollagen 1 N-Terminal Propeptide N-Terminal propeptide in a biological specimen. Propeptide Measurement Propeptide; Amino-terminal propeptide of type 1 procollagen; P1NP Aminoterm Type 1

C82033 Procollagen Type I Carboxy Procollagen A measurement of the procollagen-1 carboxy-terminal Procollagen Type I Carboxy Term Peptide Type I Carboxy peptide in a biological specimen. Terminal Peptide Measurement Term Peptide

C100446 Proerythroblast Proerythroblast A measurement of the proerythroblasts in a biological Proerythroblast Measurement specimen.

C74791 Progesterone Progesterone A measurement of the progesterone hormone in a Progesterone Measurement biological specimen.

C81967 Proinsulin Proinsulin A measurement of the proinsulin in a biological Proinsulin Measurement specimen.

C74870 Prolactin Prolactin A measurement of the prolactin hormone in a Prolactin Measurement biological specimen.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 118 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C67154 - LBTEST - Laboratory Test Name Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C74620 Prolymphocytes Prolymphocytes A measurement of the prolymphocytes in a biological Prolymphocyte Count specimen.

C64829 Prolymphocytes/Leukocytes Prolymphocytes/ A relative measurement (ratio or percentage) of Prolymphocyte To Leukocyte Ratio Leukocytes prolymphocytes to leukocytes in a biological specimen.

C74651 Prolymphocytes/Lymphocytes Prolymphocytes/ A relative measurement (ratio or percentage) of the Prolymphocyte to Lymphocyte Ratio Lymphocytes prolymphocytes to all lymphocytes in a biological Measurement specimen.

C74621 Promonocytes Promonocytes A measurement of the promonocytes in a biological Promonocyte Count specimen.

C74652 Promonocytes/Leukocytes Promonocytes/ A relative measurement (ratio or percentage) of the Promonocyte to Lymphocyte Ratio Leukocytes promonocytes to all leukocytes in a biological Measurement specimen.

C74622 Promyelocytes Promyelocytes A measurement of the promyelocytes (immature Promyelocyte Count myelocytes) in a biological specimen.

C74653 Promyelocytes/Leukocytes Promyelocytes/ A relative measurement (ratio or percentage) of the Promyelocyte to Lymphocyte Ratio Leukocytes promyelocytes (immature myelocytes) to all Measurement leukocytes in a biological specimen.

C98773 Promyelocytes/Total Cells Promyelocytes/ A relative measurement (ratio or percentage) of the Promyelocyte to Total Cell Ratio Total Cells promyelocytes (immature myelocytes) to total cells in Measurement a biological specimen (for example a bone marrow specimen).

C98870 Pronormoblasts/Total Cells Pronormoblasts/ A relative measurement (ratio or percentage) of the Pronormoblast to Total CellRatio Total Cells pronormoblasts to total cells in a biological specimen Measurement (for example a bone marrow specimen).

C74885 Propoxyphene Propoxyphene A measurement of the propoxyphene present in a Propoxyphene Measurement biological specimen.

C17634 Prostate Specific Antigen Prostate Specific A measurement of the prostate specific antigen in a Prostate Specific Antigen Antigen biological specimen. Measurement

C80204 Prostatic Acid Phosphatase Prostatic Acid A measurement of the prostatic acid phosphatase in a Prostatic Acid Phosphatase Phosphatase biological specimen. Measurement

C64858 Protein Protein A measurement of a group of complex organic Total Protein Measurement macromolecules composed of one or more alpha-L-amino acid chains in a biological specimen.

C100436 Protein S Protein S A measurement of the protein S in a biological Protein S Measurement specimen.

C79463 Protein/Creatinine Protein/ A relative measurement (ratio or percentage) of the Protein to Creatinine Ratio Creatinine protein to creatinine in a biological specimen. Measurement

C92240 Protein/Osmolality Protein/ A relative measurement (ratio or percentage) of total Protein to Osmolality Ratio Osmolality; proteins to the osmolality of a biological specimen. Measurement Protein/ Osmolality Ratio

C98774 Prothrombin Activity Prothrombin A measurement of the biological activity of Prothrombin Activity Measurement Activity prothrombin in a biological specimen.

C82034 Prothrombin Fragments 1 + 2 Prothrombin A measurement of the prothrombin fragments 1 and 2 Prothrombin Fragments 1 and 2 Fragments 1 + 2 in a biological specimen. Measurement

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 119 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C67154 - LBTEST - Laboratory Test Name Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C64805 Prothrombin Intl. Normalized Prothrombin Intl. A ratio that represents the prothrombin time for a International Normalized Ratio of Ratio Normalized plasma specimen, divided by the result for a control Prothrombin Time Ratio plasma specimen, further standardized for the International Sensitivity Index of the tissue factor (thromboplastin) used in the test.

C62656 Prothrombin Time Prothrombin A blood clotting measurement that evaluates the Prothrombin Time Time extrinsic pathway of coagulation.

C74696 Pseudoephedrine Pseudoephedrine A measurement of the pseudoephedrine present in a Pseudoephedrine Measurement biological specimen.

C80211 Pyridinoline Pyridinoline A measurement of the pyridinoline in a biological Pyridinoline Measurement specimen.

C74772 RBC Casts RBC Casts A measurement of the red blood cell casts present in a Red Blood Cell Cast Measurement biological specimen.

C74716 Rapid Plasma Reagin Rapid Plasma A measurement of the antibodies produced by cellular Rapid Plasma Reagin Measurement Reagin damage caused by Treponema pallidum (syphilis) in a biological specimen.

C74629 Reactive Lymphocytes Reactive A measurement of the reactive lymphocytes Reactive Lymphocyte Count Lymphocytes (lymphocytes which have become large due to an Measurement antigen reaction) in a biological specimen.

C74654 Reactive Reactive A relative measurement (ratio or percentage) of the Reactive Lymphocyte to Lymphocytes/Lymphocytes Lymphocytes/ reactive lymphocytes (lymphocytes which have Lymphocyte Ratio Measurement Lymphocytes become large due to an antigen reaction) to all lymphocytes in a biological specimen.

C81957 Reg upon Act Normal T-cell Reg upon Act A measurement of the RANTES (regulated on Reg upon Act Normal T-cell Exprd Exprd Secrtd Normal T-cell activation, normally, T-cell expressed, and secreted) Secrtd Measurement Exprd Secrtd; chemokine in a biological specimen. Chemokine Ligand 5

C74893 Renin Renin; A measurement of the renin in a biological specimen. Renin Measurement Angiotensinogen ase

C96628 Reptilase Time Reptilase Time A measurement of the time it takes a plasma sample to Reptilase Time Measurement clot after adding the active enzyme reptilase.

C80205 Resistin Resistin A measurement of the resistin in a biological Resistin Measurement specimen.

C98776 Reticulocyte Hemoglobin Reticulocyte A measurement of the amount of hemoglobin in Reticulocyte Hemoglobin Hemoglobin reticulocytes. Measurement

C51947 Reticulocytes Reticulocytes A measurement of the reticulocytes in a biological Reticulocyte Count specimen.

C64828 Reticulocytes/Erythrocytes Reticulocytes/ A relative measurement (ratio or percentage) of Reticulocyte To Erythrocyte Ratio Erythrocytes reticulocytes to erythrocytes in a biological specimen.

C100437 Retinol Binding Protein Retinol Binding A measurement of the total retinol binding protein in a Retinol Binding Protein Protein biological specimen. Measurement

C74717 Rheumatoid Factor Rheumatoid A measurement of the rheumatoid factor antibody in a Rheumatoid Factor Measurement Factor biological specimen.

C74898 Riboflavin Riboflavin; A measurement of the riboflavin in a biological Vitamin B2 Measurement Vitamin B2 specimen.

C100457 Ribonucleoprotein Antibody Ribonucleoprote A measurement of the ribonucleoprotein antibody in a Ribonucleoprotein Antibody in Antibody; biological specimen. Measurement RNP Antibody

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 120 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C67154 - LBTEST - Laboratory Test Name Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C100419 Ringed Sideroblasts Ringed A measurement of the ringed sideroblasts (abnormal Ringed Sideroblast Measurement Sideroblasts nucleated erythroblasts with a large number of iron deposits in the perinuclear mitochondria, forming a ring around the nucleus) in a biological specimen.

C74624 Rouleaux Formation Rouleaux A measurement of the number of stacking red blood Rouleaux Formation Count Formation cells within a biological specimen.

C74698 Round Epithelial Cells Round Epithelial A measurement of the round epithelial cells present in Round Epithelial Cell Count Cells a biological specimen.

C74706 Schistocytes Schistocytes A measurement of the schistocytes (fragmented red Schistocyte Count blood cells) in a biological specimen.

C100458 Scl-70 Antibody Scl-70 Antibody; A measurement of the Scl-70 antibody in a biological Scl-70 Antibody Measurement Scleroderma-70 specimen. Antibody

C74871 Secretin Secretin A measurement of the secretin hormone in a Secretin Measurement biological specimen.

C74872 Serotonin Serotonin A measurement of the serotonin hormone in a Serotonin Measurement biological specimen.

C74745 Sex Hormone Binding Sex Hormone A measurement of the sex hormone binding (globulin) Sex Hormone Binding Protein Globulin Binding protein in a biological specimen. Measurement Globulin; Sex Hormone Binding Protein

C74625 Sezary Cells Sezary Cells A measurement of the Sezary cells (atypical Sezary Cell Count lymphocytes with cerebriform nuclei) in a biological specimen.

C74655 Sezary Cells/Lymphocytes Sezary A relative measurement (ratio or percentage of the Sezary Cell to Lymphocyte Ratio Cells/ Sezary cells (atypical lymphocytes with cerebriform Measurement Lymphocytes nuclei) to all lymphocytes in a biological specimen.

C74626 Sickle Cells Sickle Cells A measurement of the sickle cells (sickle shaped red Sickle Cell Count blood cells) in a biological specimen.

C74656 Sickle Cells/Erythrocytes Sickle A relative measurement (ratio or percentage) of the Sickle Cell to Erythrocyte Ratio Cells/ sickle cells (sickle shaped red blood cells) to all Measurement Erythrocytes erythrocytes in a biological specimen.

C100418 Sideroblast Sideroblast A measurement of the sideroblasts (nucleated Sideroblast Measurement erythroblasts with iron granules in the cytoplasm) in a biological specimen.

C92236 Sjogrens SS-A Antibody Ro Antibody; A measurement of the Sjogrens SS-A antibody in a Sjogren's SS-A Antibody Sjogrens SS-A biological specimen. Measurement Antibody

C92237 Sjogrens SS-B Antibody La Antibody; A measurement of the Sjogrens SS-B antibody in a Sjogren's SS-B Antibody Sjogrens SS-B biological specimen. Measurement Antibody

C92281 Smith Antibody Smith Antibody A measurement of the Smith antibody in a biological Smith Antibody Measurement specimen.

C74627 Smudge Cells Smudge Cells; A measurement of the smudge cells (the nuclear Smudge Cell Count Basket Cells remnant of a ruptured white blood cell) in a biological specimen.

C64809 Sodium Sodium A measurement of the sodium in a biological Sodium Measurement specimen.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 121 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C67154 - LBTEST - Laboratory Test Name Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C79464 Sodium/Creatinine Sodium/ A relative measurement (ratio or percentage) of the Sodium to Creatinine Ratio Creatinine sodium to creatinine in a biological specimen. Measurement

C100438 Soluble Transferrin Receptor Soluble A measurement of the soluble transferrin receptor in a Soluble Transferrin Receptor Transferrin biological specimen. Measurement Receptor

C92533 Soluble Vasc Cell Adhesion Soluble Vascular A measurement of the soluble vascular cell adhesion Soluble Vascular Cell Adhesion Molecule 1 Cell Adhesion molecule 1 in a biological specimen. Molecule 1 Molecule 1

C80360 Somatotrophin Somatotrophin; A measurement of the somatotrophin (growth) Somatotropin Measurement Growth hormone in a biological specimen. Hormone

C79465 Sorbitol Dehydrogenase Sorbitol A measurement of the sorbitol dehydrogenase in a Sorbitol Dehydrogenase Dehydrogenase biological specimen. Measurement

C64832 Specific Gravity Specific Gravity A ratio of the density of a fluid to the density of water. Specific Gravity

C25377 Specimen Appearance Specimen The outward or visible aspect of a specimen. Appearance Appearance

C74663 Spermatozoa Spermatozoa A measurement of the spermatozoa cells present in a Spermatozoa Cell Count biological specimen.

C74707 Spherocytes Spherocytes A measurement of the spherocytes (small, Spherocyte Count sphere-shaped red blood cells) in a biological specimen.

C74773 Squamous Epithelial Cells Squamous A measurement of the squamous epithelial cells Squamous Epithelial Cell Count Epithelial Cells present in a biological specimen.

C74774 Squamous Transitional Squamous A measurement of the squamous transitional epithelial Squamous Transitional Epithelial Epithelial Cells Transitional cells present in a biological specimen. Cell Count Epithelial Cells; Epithelial Cells

C81951 Starch Crystals Starch Crystals A measurement of the starch crystals in a biological Starch Crystal Measurement specimen.

C82035 Stem Cell Factor Stem Cell A measurement of the stem cell factor in a biological Stem Cell Factor Measurement Factor; KIT specimen. Ligand

C74708 Stomatocytes Stomatocytes A measurement of the stomatocytes (red blood cells Stomatocyte Count with an oval or rectangular area of central pallor, producing the appearance of a cell mouth) in a biological specimen.

C92282 Streptolysin O Antibody Streptolysin O A measurement of Streptolysin O Antibody in a Streptolysin O Antibody Antibody; biological specimen. Measurement Antistreptolysin O

C74755 Sulfa Crystals Sulfa Crystals A measurement of the sulfa crystals present in a Sulfa Crystal Measurement biological specimen.

C96636 Target Cells Leptocytes; A measurement of the target cells in a biological Target Cell Count Target Cells specimen.

C84810 Tau Protein Tau Protein; A measurement of the total Tau protein in a biological Tau Protein Measurement Total Tau Protein specimen.

C74793 Testosterone Testosterone; A measurement of the total (free and bound) Total Testosterone Measurement Total testosterone in a biological specimen. Testosterone

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 122 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C67154 - LBTEST - Laboratory Test Name Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C74785 Testosterone, Free Testosterone, A measurement of the free testosterone in a biological Free Testosterone Measurement Free specimen.

C74896 Thiamine Thiamine; A measurement of the thiamine in a biological Vitamin B1 Measurement Vitamin B1 specimen.

C80365 Thrombin Time Thrombin Time A measurement of the time it takes a plasma sample to Thrombin Time clot after adding the active enzyme thrombin. (NCI)

C74873 Thrombopoietin Thrombopoietin A measurement of the thrombopoietin hormone in a Thrombopoietin Measurement biological specimen.

C81990 Thyroid Antibodies Thyroid A measurement of the thyroid antibodies in a Thyroid Antibody Measurement Antibodies biological specimen.

C81991 Thyroid Antimicrosomal Thyroid A measurement of the thyroid antimicrosomal Thyroid Antimicrosomal Antibody Antibodies Antimicrosomal antibodies in a biological specimen. Measurement Antibodies

C81992 Thyroid Antithyroglobulin Thyroid A measurement of the thyroid antithyroglobulin Thyroid Antithyroglobulin Antibody Antibodies Antithyroglobuli antibodies in a biological specimen. Measurement n Antibodies

C96639 Thyroperoxidase Thyroperoxidase; A measurement of the thyroperoxidase in a biological Thyroperoxidase Measurement Thyroid specimen. Peroxidase

C96638 Thyroperoxidase Antibody Thyroperoxidase A measurement of the thyroperoxidase antibody in a Thyroperoxidase Antibody Antibody biological specimen. Measurement

C64813 Thyrotropin Thyrotropin A measurement of the thyrotropin in a biological Thyrotropin Measurement specimen.

C74874 Thyrotropin Releasing Thyrotropin A measurement of the thyrotropin releasing hormone Thyrotropin Releasing Hormone Hormone Releasing in a biological specimen. Measurement Hormone; Thyrotropin Releasing Factor

C74794 Thyroxine Thyroxine; Total A measurement of the total (free and bound) thyroxine Total Thyroxine Measurement T4 in a biological specimen.

C74746 Thyroxine Binding Globulin Thyroxine A measurement of the thyroxine binding globulin Thyroxine Binding Globulin Protein Binding Globulin protein in a biological specimen. Measurement

C74786 Thyroxine, Free Thyroxine, Free; A measurement of the free thyroxine in a biological Free Thyroxine Measurement Free T4 specimen.

C82036 Tissue Inhibitor of Tissue Inhibitor A measurement of the tissue inhibitor of Tissue Inhibitor of Metalloproteinase 1 of metalloproteinase 1 in a biological specimen. Metalloproteinase 1 Measurement Metalloproteinas e 1

C81993 Tissue Plasminogen Activator Tissue A measurement of the tissue plasminogen activator Tissue Plasminogen Activator Antigen Plasminogen antigen in a biological specimen. Antigen Measurement Activator Antigen

C74718 Total Iron Binding Capacity Total Iron A measurement of the amount of iron needed to fully Total Iron Binding Capacity Binding Capacity saturate the transferrin in a biological specimen.

C80208 Total Radical-Trap Antioxidant Total A measurement of the ability of the antioxidants in a Total Radical-Trap Antioxidant Potential Radical-Trap biological specimen to buffer free radicals in a Potential Measurement Antioxidant suspension. Potential

C96641 Toxic Granulation Toxic A measurement of the toxic granulation in neutrophilic Toxic Granulation Measurement Granulation blood cells.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 123 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C67154 - LBTEST - Laboratory Test Name Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C82037 Transferrin Transferrin A measurement of the transferrin in a biological Transferrin Measurement specimen.

C98792 Transferrin Saturation Transferrin A measurement of the iron bound to transferrin in a Transferrin Saturation Measurement Saturation biological specimen.

C92251 Transitional Epithelial Cells Transitional A measurement of the transitional epithelial cells Transitional Epithelial Cells Epithelial Cells present in a biological specimen. Measurement

C64807 Triacylglycerol Lipase Triacylglycerol A measurement of the pancreatic lipase in a biological Triacylglycerol Lipase Measurement Lipase specimen.

C92238 Trichomonas Trichomonas Examination of a biological specimen to detect the Trichomonas Screening presence of any protozoan belonging to the Trichomonas genus.

C100420 Tricyclic Antidepressants Tricyclic A measurement of tricyclic antidepressants in a Tricyclic Antidepressant Antidepressants biological specimen. Measurement

C64812 Triglycerides Triglycerides A measurement of the triglycerides in a biological Triglyceride Measurement specimen.

C74747 Triiodothyronine Triiodothyronine A measurement of the total (free and bound) Triiodothyronine Measurement ; Total T3 triiodothyronine in a biological specimen.

C74748 Triiodothyronine Uptake Triiodothyronine A measurement of the binding of triiodothyonine to Triiodothyronine Uptake Uptake thyroxine binding globulin protein in a biological Measurement specimen.

C74787 Triiodothyronine, Free Triiodothyronine A measurement of the free triiodothyronine in a Free Triiodothyronine Measurement , Free; Free T3 biological specimen.

C81968 Triiodothyronine, Reverse Triiodothyronine A measurement of the reverse triiodothyronine in a Reverse Triiodothyronine , Reverse biological specimen. Measurement

C74756 Triple Phosphate Crystals Triple Phosphate A measurement of the triple phosphate crystals present Triple Phosphate Crystal Crystals in a biological specimen. Measurement

C74749 Troponin I Troponin I A measurement of the actin binding troponin in a Troponin I Measurement biological specimen.

C74750 Troponin T Troponin T A measurement of the tropomyosin binding troponin in Troponin T Measurement a biological specimen.

C92292 Tryptase Tryptase A measurement of the tryptase in a biological Tryptase Measurement specimen.

C74775 Tubular Epithelial Cells Tubular A measurement of the tubular epithelial cells present Tubular Epithelial Cell Count Epithelial Cells; in a biological specimen. Renal Tubular Epithelial Cells

C74751 Tumor Necrosis Factor Tumor Necrosis A measurement of the total tumor necrosis factor Tumor Necrosis Factor Factor; Tumor (cachexin) cytokine in a biological specimen. Measurement Necrosis Factor alpha

C74723 Turbidity Turbidity A measurement of the opacity of a biological Turbidity Measurement specimen.

C82038 Type I Collagen Type I Collagen A measurement of the type I collagen C-telopeptides Type I Collagen C-Telopeptide C-Telopeptides C-Telopeptides; in a biological specimen. Measurement Type I Collagen X-linked C-telopeptide

C82039 Type I Collagen Type I Collagen A measurement of the type I collagen N-telopeptides Type I Collagen N-Telopeptide N-Telopeptides N-Telopeptides in a biological specimen. Measurement

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 124 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C67154 - LBTEST - Laboratory Test Name Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C92283 Type I Myeloblasts Type I A measurement of type I myeloblast cells per unit of a Type I Myeloblasts Measurement Myeloblasts biological specimen.

C82040 Type II Collagen Type II Collagen A measurement of the type II collagen C-telopeptides Type II Collagen C-Telopeptide C-Telopeptides C-Telopeptides in a biological specimen. Measurement

C82041 Type II Collagen Type II Collagen A measurement of the type II collagen N-telopeptides Type II Collagen N-Telopeptide N-Telopeptides N-Telopeptides in a biological specimen. Measurement

C92284 Type II Myeloblasts Type II A measurement of type II myeloblast cells per unit of a Type II Myeloblasts Measurement Myeloblasts biological specimen.

C92285 Type III Myeloblasts Type III A measurement of type III myeloblast cells per unit of Type III Myeloblasts Measurement Myeloblasts a biological specimen.

C74683 Tyrosine Crystals Tyrosine A measurement of the triple phosphate crystals present Tyrosine Crystal Measurement Crystals in a biological specimen.

C74776 Unclassified Casts Unclassified A measurement of the unclassifiable casts present in a Unclassified Cast Measurement Casts biological specimen.

C74757 Unclassified Crystals Unclassified A measurement of the unclassifiable crystals present Unclassified Crystal Measurement Crystals in a biological specimen.

C74719 Unsaturated Iron Binding Unsaturated Iron A measurement of the binding capacity of unsaturated Unsaturated Iron Binding Capacity Capacity Binding Capacity iron in a biological specimen. Measurement

C64814 Urate Urate; Uric Acid A measurement of the urate in a biological specimen. Urate Measurement

C64815 Urea Urea A measurement of the urea in a biological specimen. Urea Measurement

C96645 Urea/Creatinine Urea/Creatinine A relative measurement (ratio or percentage) of the Urea to Creatinine Ratio urea to creatinine in a biological specimen. Measurement

C74684 Uric Acid Crystals Uric Acid A measurement of the uric acid crystals present in a Uric Acid Crystal Measurement Crystals biological specimen.

C64816 Urobilinogen Urobilinogen A measurement of the urobilinogen in a biological Urobilinogen Measurement specimen.

C64806 VLDL Cholesterol VLDL A measurement of the very low density lipoprotein Serum VLDL Cholesterol Cholesterol cholesterol in a biological specimen. Measurement

C74628 Vacuolated Neutrophils Vacuolated A measurement of the neutrophils containing small Vacuolated Neutrophil Count Neutrophils vacuoles in a biological specimen.

C74875 Vanillyl Mandelic Acid Vanillyl A measurement of the vanillyl mandelic acid Vanillyl Mandelic Acid Mandelic Acid; metabolite in a biological specimen. Measurement Vanilmandelic Acid

C98795 Varicella Zoster Virus IgA Varicella Zoster A measurement of the Varicella Zoster virus IgA Varicella Zoster Virus IgA Antibody Antibody Virus IgA antibodies in a biological specimen. Measurement Antibody

C98796 Varicella Zoster Virus IgG Varicella Zoster A measurement of the Varicella Zoster virus IgG Varicella Zoster Virus IgG Antibody Antibody Virus IgG antibodies in a biological specimen. Measurement Antibody

C98797 Varicella Zoster Virus IgM Varicella Zoster A measurement of the Varicella Zoster virus IgM Varicella Zoster Virus IgM Antibody Antibody Virus IgM antibodies in a biological specimen. Measurement Antibody

C82042 Vascular Cell Adhesion Vascular Cell A measurement of the vascular cell adhesion molecule Vascular Cell Adhesion Molecule 1 Molecule 1 Adhesion 1 in a biological specimen. Measurement Molecule 1

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 125 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C67154 - LBTEST - Laboratory Test Name Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C92514 Vascular Endothelial Growth Vascular A measurement of the vascular endothelial growth Vascular Endohelial Growth Factor Factor Endothelial factor in a biological specimen. Measurement Growth Factor

C75912 Viscosity Viscosity The resistance of a liquid to sheer forces and flow. Viscosity (NCI)

C74895 Vitamin A Vitamin A; A measurement of the Vitamin A in a biological Vitamin A Measurement Retinol specimen.

C64817 Vitamin B12 Vitamin B12 A measurement of the Vitamin B12 in a serum Vitamin B12 Measurement specimen.

C74897 Vitamin B17 Vitamin B17; A measurement of the Vitamin B17 in a biological Vitamin B17 Measurement Amygdalin specimen.

C74900 Vitamin B5 Vitamin B5; A measurement of the Vitamin B5 in a biological Vitamin B5 Measurement Pantothenic Acid specimen.

C74901 Vitamin B6 Vitamin B6; A measurement of the Vitamin B6 in a biological Vitamin B6 Measurement Pyridoxine specimen.

C74902 Vitamin B7 Vitamin B7; A measurement of the Vitamin B7 in a biological Vitamin B7 Measurement Biotin specimen.

C74676 Vitamin B9 Folic Acid; A measurement of the folic acid in a biological Folic Acid Measurement Vitamin B9 specimen.

C74903 Vitamin C Vitamin C; A measurement of the Vitamin C in a biological Vitamin C Measurement Ascorbic Acid specimen.

C84818 Vitamin D Vitamin D; Total A measurement of the total Vitamin D in a biological Vitamin D Measurement Vitamin D specimen.

C74904 Vitamin D2 Vitamin D2; A measurement of the Vitamin D2 in a biological Vitamin D2 Measurement Ergocalciferol specimen.

C74905 Vitamin D3 Vitamin D3; A measurement of the Vitamin D3 in a biological Vitamin D3 Measurement Cholecalciferol specimen.

C74906 Vitamin E Vitamin E; A measurement of the Vitamin E in a biological Vitamin E Measurement Tocopherol specimen.

C74907 Vitamin K Vitamin K; A measurement of the Vitamin K in a biological Vitamin K Measurement Naphthoquinone specimen.

C74720 Volume Volume A measurement of the volume of a biological Volume Measurement specimen.

C74778 WBC Casts WBC Casts A measurement of the white blood cell casts present in White Blood Cell Cast Measurement a biological specimen.

C74777 Waxy Casts Waxy Casts A measurement of the waxy casts present in a Waxy Cell Cast Measurement biological specimen.

C74664 Yeast Cells Yeast Cells A measurement of the yeast cells present in a Yeast Cell Measurement biological specimen.

C92239 Yeast Hyphae Yeast Hyphae Examination of a biological specimen to detect the Yeast Hyphae Screening presence of any yeast cells that are in the long, filamentous and branching phase of growth.

C80210 Zinc Zinc A measurement of the zinc in a biological specimen. Zinc Measurement

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 126 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C67154 - LBTEST - Laboratory Test Name Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C45997 pH pH A measure of the acidity or alkalinity of a fluid on a pH scale of 0 to 14.

C98799 von Willebrand Factor von Willebrand A measurement of the von Willebrand factor in a von Willebrand Factor Measurement Factor biological specimen.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 127 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C65047 - LBTESTCD - Laboratory Test Code Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C100429 A1AGLP Alpha-1 Acid A measurement of the alpha-1 acid glycoprotein in a Alpha-1 Acid Glycoprotein Glycoprotein biological specimen. Measurement

C80167 A1ANTRYP Alpha-1 A measurement of the alpha-1 antitrypsin in a Alpha-1 Antitrypsin Measurement Antitrypsin; biological specimen. Serum Trypsin Inhibitor

C100462 A1MCREAT Alpha-1 A relative measurement (ratio or percentage) of the Alpha-1 Microglobulin to Creatinine Microglobulin/ alpha-1 microglobulin to creatinine in a biological Ratio Measurement Creatinine specimen.

C100461 A1MICG Alpha-1 A measurement of the alpha-1 microglobulin in a Alpha-1 Microglobulin Measurement Microglobulin; biological specimen. Protein HC

C80168 A2MACG Alpha-2 A measurement of the alpha-2 macroglobulin in a Alpha-2 Macroglobulin Macroglobulin biological specimen. Measurement

C100430 AAP Alanine A measurement of the alanine aminopeptidase in a Alanine Aminopeptidase Aminopeptidase biological specimen. Measurement

C74699 ACANT Acanthocytes A measurement of the acanthocytes in a biological Acanthocyte Count specimen.

C74633 ACANTRBC Acanthocytes/ A relative measurement (ratio or percentage) of Acanthocyte to Erythrocyte Ratio Erythrocytes acanthocytes to all erythrocytes in a biological Measurement specimen.

C80169 ACE Angiotensin A measurement of the angiotensin converting enzyme Angiotensin Converting Enzyme Converting in a biological specimen. Measurement Enzyme

C92247 ACETOAC Acetoacetic A measurement of the acetoacetic acid in a biological Acetoacetic Acid Measurement Acid; specimen. Acetoacetate

C74838 ACH Acetylcholine A measurement of the acetylcholine hormone in a Acetylcholine Measurement biological specimen.

C96560 ACHE Acetylcholineste A measurement of the acetylcholinesterase in a Acetylcholinesterase Measurement rase biological specimen.

C96559 ACHRAB Acetylcholine A measurement of the acetylcholine receptor antibody Acetylcholine Receptor Antibody Receptor in a biological specimen. Measurement Antibody

C80163 ACPHOS Acid A measurement of the acid phosphatase in a biological Acid Phosphatase Measurement Phosphatase specimen.

C74780 ACTH Adrenocorticotr A measurement of the adrenocorticotropic hormone in Adrenocorticotropic Hormone opic Hormone a biological specimen. Measurement

C92286 ACYLCAOX Acyl Coenzyme A measurement of the acyl coenzyme A oxidase in a Acyl Coenzyme A Oxidase A Oxidase; Fatty biological specimen. Measurement Acyl Coenzyme A Oxidase; Acyl CoA Oxidase

C74847 ADH Antidiuretic A measurement of the antidiuretic hormone in a Antidiuretic Hormone Measurement Hormone; biological specimen. Vasopressin

C74839 ADPNCTN Adiponectin A measurement of the adiponectin hormone in a Adiponectin Measurement biological specimen.

C74913 ADSDNA Anti-Double A measurement of the anti-double stranded DNA Anti-Double Stranded DNA Stranded DNA antibody in a biological specimen. Measurement

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 128 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C65047 - LBTESTCD - Laboratory Test Code Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C98705 ADVVLD ADV Viral Load A measurement of the adenovirus viral load in a Adenovirus Viral Load Measurement biological specimen.

C98706 AFACTXAA Anti-Factor Xa A measurement of the anti-activated Factor X in a Anti-Factor Xa Activity Activity biological specimen. This test is used to monitor low Measurement molecular weight or unfractionated heparin levels in a biological specimen.

C74732 AFP Alpha A measurement of the alpha fetoprotein in a biological Alpha-fetoprotein Measurement Fetoprotein specimen.

C96562 AFPL1 Alpha A measurement of the alpha fetoprotein L1 in a Alpha Fetoprotein L1 Measurement Fetoprotein L1 biological specimen.

C96563 AFPL2 Alpha A measurement of the alpha fetoprotein L2 in a Alpha Fetoprotein L2 Measurement Fetoprotein L2 biological specimen.

C96564 AFPL3 Alpha A measurement of the alpha fetoprotein L3 in a Alpha Fetoprotein L3 Measurement Fetoprotein L3 biological specimen.

C96565 AFPL3AFP A Fetoprotein A relative measurement (ratio or percentage) of alpha Alpha Fetoprotein L3 to Total Alpha L3/A Fetoprotein fetoprotein L3 to total alpha fetoprotein in a biological Fetoprotein Ratio Measurement specimen.

C64431 ALB Albumin; A measurement of the albumin protein in a biological Albumin Measurement Microalbumin specimen.

C74761 ALBCREAT Albumin/ A relative measurement (ratio or percentage) of the Albumin To Creatinine Protein Ratio Creatinine; albumin to the creatinine in a biological specimen. Measurement Microalbumin/ Creatinine Ratio

C74894 ALBGLOB Albumin/ The ratio of albumin to globulin in a biological Albumin to Globulin Ratio Globulin specimen. Measurement

C74731 ALDOLASE Aldolase A measurement of the aldolase enzyme in a biological Aldolase Measurement specimen.

C74841 ALDSTRN Aldosterone A measurement of the aldosterone hormone in a Aldosterone Measurement biological specimen.

C64432 ALP Alkaline A measurement of the alkaline phosphatase in a Alkaline Phosphatase Measurement Phosphatase biological specimen.

C92287 ALPBS Bone Specific A measurement of the bone specific alkaline Bone Specific Alkaline Phosphatase Alkaline phosphatase isoform in a biological specimen. Measurement Phosphatase

C79438 ALPCREAT Alkaline A relative measurement (ratio or percentage) of the Alkaline Phosphatase to Creatinine Phosphatase/ alkaline phosphatase to creatinine in a biological Ratio Measurement Creatinine specimen.

C64433 ALT Alanine A measurement of the alanine aminotransferase in a Alanine Aminotransferase Aminotransferas biological specimen. Measurement e; SGPT

C81975 AMA Antimitochondri A measurement of the antimitochondrial antibodies in Antimitochondrial Antibody al Antibodies; a biological specimen. Measurement Mitochondrial Antibody

C74799 AMMONIA Ammonia; NH3 A measurement of the ammonia in a biological Ammonia Measurement specimen.

C74666 AMORPHSD Amorphous A measurement of the amorphous sediment present in Amorphous Sediment Measurement Sediment; a biological specimen. Amorphous Debris

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 129 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C65047 - LBTESTCD - Laboratory Test Code Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C74687 AMPHET Amphetamine A measurement of any amphetamine class drug present Amphetamine Drug Class in a biological specimen. Measurement

C64434 AMYLASE Amylase A measurement of the total enzyme amylase in a Amylase Measurement biological specimen.

C98767 AMYLASEP Amylase, A measurement of the pancreatic enzyme amylase in a Pancreatic Amylase Measurement Pancreatic biological specimen.

C98780 AMYLASES Amylase, A measurement of the salivary enzyme amylase in a Salivary Amylase Measurement Salivary biological specimen.

C84809 AMYLB42 Amyloid Beta A measurement of the 42 amino acid amyloid beta Beta Amyloid 42 Measurement 42; Amyloid protein isoform in a biological specimen. Beta 42 Protein

C81999 AMYLOIDB Amyloid, Beta; A measurement of the total amyloid beta in a Beta Amyloid Measurement Beta Amyloid biological specimen.

C81998 AMYLOIDP Amyloid P A measurement of the total amyloid P in a biological Amyloid P Measurement specimen.

C74916 ANA Antinuclear A measurement of the antinuclear antibodies Antinuclear Antibody Measurement Antibodies (antibodies that attack the body's own tissue) in a biological specimen.

C74842 ANDSTNDL Androstenediol A measurement of the androstenediol metabolite in a Androstenediol Metabolite biological specimen. Measurement

C74843 ANDSTNDN Androstenedione A measurement of the androstenedione hormone in a Androstenedione Measurement ; biological specimen. 4-Androstenedio ne

C81974 ANGLOBDR Antiglobulin A measurement of the antibody or complement-coated Direct Antiglobulin Test Test, Direct; erythrocytes in a biological specimen in vivo. Direct Coombs Test

C74844 ANGTNS1 Angiotensin I A measurement of the angiotensin I hormone in a Angiotensin I Measurement biological specimen.

C74845 ANGTNS2 Angiotensin II A measurement of the angiotensin II hormone in a Angiotensin II Measurement biological specimen.

C74846 ANGTNSGN Angiotensinogen; A measurement of the angiotensinogen hormone in a Angiotensinogen Measurement Angiotensin biological specimen. Precursor

C74685 ANIONG Anion Gap A computed estimate of the unmeasured anions (those Anion Gap Measurement other than the chloride and bicarbonate anions) in a biological specimen.

C74797 ANISO Anisocytes A measurement of the inequality in the size of the red Anisocyte Measurement blood cells in a whole blood specimen.

C74886 ANP Atrial Natriuretic A measurement of the atrial natriuretic peptide in a Atrial Natriuretic Peptide Peptide; biological specimen. Measurement Atriopeptin

C81958 ANTHRM Antithrombin; A measurement of the antithrombin activity in a Antithrombin Measurement Antithrombin III; biological specimen. Antithrombin Activity; Antithrombin III Activity

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 130 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C65047 - LBTESTCD - Laboratory Test Code Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C81977 ANTHRMAG Antithrombin A measurement of the antithrombin antigen in a Antithrombin Antigen Measurement Antigen; biological specimen. Antithrombin III Antigen

C74691 ANTIDPRS Antidepressants A measurement of any antidepressant class drug Antidepressant Measurement present in a biological specimen.

C74733 APOA1 Apolipoprotein A measurement of the apolipoprotein A1 in the high Apolipoprotein A1 Measurement A1 density lipoproteins of a biological specimen.

C82000 APOA2 Apolipoprotein A measurement of the apolipoprotein AII in a Apolipoprotein AII Measurement AII biological specimen.

C74734 APOB Apolipoprotein B A measurement of the apolipoprotein B in the low Apolipoprotein B Measurement density lipoproteins of a biological specimen.

C100427 APOC2 Apolipoprotein A measurement of the apolipoprotein C2 in a Apolipoprotein C2 Measurement C2; biological specimen. Apolipoprotein CII

C82001 APOC3 Apolipoprotein A measurement of the apolipoprotein CIII in a Apolipoprotein CIII Measurement CIII biological specimen.

C82002 APOE Apolipoprotein E A measurement of the apolipoprotein E in a biological Apolipoprotein E Measurement specimen.

C92293 APOE4 Apolipoprotein A measurement of the apolipoprotein E4 in a Apolipoprotein E4 Measurement E4 biological specimen.

C82003 APOH Apolipoprotein A measurement of the apolipoprotein H in a biological Apolipoprotein H Measurement H specimen.

C100428 APOJ Apolipoprotein J; A measurement of the apolipoprotein J in a biological Apolipoprotein J Measurement Clusterin specimen.

C25377 APPEAR Specimen The outward or visible aspect of a specimen. Appearance Appearance

C100471 APROTCRS Activated Protein A measurement of the resistance in the anticoagulation Activated Protein C Resistance C Resistance; response to activated protein C in a biological Measurement Factor V Leiden specimen. Screen

C38462 APTT Activated Partial A measurement of the length of time that it takes for Partial Thromboplastin Time Thromboplastin clotting to occur when reagents are added to a plasma Time specimen. The test is partial due to the absence of tissue factor (Factor III) from the reaction mixture.

C100421 APTTSPTT Activated A relative measurement (ratio or percentage) of the Activated PTT to Standard PTT Ratio PTT/Standard subject's activated partial thromboplastin time to a Measurement PTT; Activated standard or control partial thromboplastin time. Partial Thromboplastin Time/Standard Thromboplastin Time

C98862 APTTSTND Activated A relative measurement (ratio or percentage) of the Activated PTT/Standard Ratio PTT/Standard subject's partial thromboplastin time to a standard or Measurement control partial thromboplastin time.

C81976 ASCAB Anti-Saccharomy A measurement of the anti-Saccharomyces cerevisiae Anti-Saccharomyces cerevisiae ces cerevisiae antibody in a biological specimen. Antibody Measurement Antibody

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 131 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C65047 - LBTESTCD - Laboratory Test Code Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C92269 ASSDNA Anti-Single A measurement of the anti-single stranded DNA IgG Anti-Single Stranded DNA IgG Stranded DNA antibody in a biological specimen. Measurement IgG

C64467 AST Aspartate A measurement of the aspartate aminotransferase in a Aspartate Aminotransferase Aminotransferas biological specimen. Measurement e; SGOT

C81978 ASTAG Aspartate A measurement of the aspartate aminotransferase Aspartate Aminotransferase Antigen Aminotransferas antigen in a biological specimen. Measurement e Antigen; SGOT Antigen

C74657 AUERRODS Auer Rods A measurement of the Auer rods (elongated needle Auer Rod Measurement structures that are found in the cytoplasm of leukemic blasts and are formed by clumps of azurophilic granular material) in a biological specimen.

C81979 B2GLYAB Beta-2 A measurement of the beta-2 glycoprotein antibody in Beta-2 Glycoprotein Antibody Glycoprotein a biological specimen. Measurement Antibody

C81980 B2MICG Beta-2 A measurement of the beta-2 microglobulin in a Beta-2 Microglobulin Measurement Microglobulin biological specimen.

C64469 BACT Bacteria A measurement of the bacteria in a biological Bacterial Count specimen.

C74688 BARB Barbiturates A measurement of any barbiturate class drug present in Barbiturate Drug Class Measurement a biological specimen.

C64470 BASO Basophils A measurement of the basophils in a biological Total Basophil Count specimen.

C98865 BASOCE Basophils/Total A relative measurement (ratio or percentage) of the Basophil to Total CellRatio Cells basophils to total cells in a biological specimen (for Measurement example a bone marrow specimen).

C96670 BASOIM Immature A measurement of the immature basophils in a Immature Basophil Count Basophils biological specimen.

C96671 BASOIMLE Immature A relative measurement (ratio or percentage) of Immature Basophil to Leukocyte Basophils/ immature basophils to total leukocytes in a biological Ratio Measurement Leukocytes specimen.

C64471 BASOLE Basophils/ A relative measurement (ratio or percentage) of the Basophil To Leukocyte Ratio Leukocytes basophils to leukocytes in a biological specimen.

C82004 BDNF Brain-Derived A measurement of the brain-derived neurotrophic Brain-Derived Neurotrophic Factor Neurotrophic factor in a biological specimen. Measurement Factor

C100472 BETACRTN Beta Carotene; A measurement of the beta carotene in a biological Beta Carotene Measurement b-Carotene; Beta specimen. Carotin

C96568 BHYXBTR Beta-Hydroxybut A measurement of the total Beta-hydroxybutyrate in a Beta-Hydroxybutyrate Measurement yrate; biological specimen. B-Hydroxybutyra te; 3-Hydroxybutyra te

C74667 BICARB Bicarbonate; A measurement of the bicarbonate in a biological Bicarbonate Measurement HCO3 specimen.

C64481 BILDIR Direct Bilirubin A measurement of the conjugated or water-soluble Direct Bilirubin Measurement bilirubin in a biological specimen.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 132 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C65047 - LBTESTCD - Laboratory Test Code Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C74800 BILEAC Bile Acid; Bile A measurement of the total bile acids in a biological Bile Acid Measurement Salts; Bile Acids; specimen. Bile Salt

C38037 BILI Bilirubin; Total A measurement of the total bilirubin in a biological Total Bilirubin Measurement Bilirubin specimen.

C64483 BILIND Indirect Bilirubin A measurement of the unconjugated or Indirect Bilirubin Measurement non-water-soluble bilirubin in a biological specimen.

C74700 BITECE Bite Cells A measurement of the bite cells (erythrocytes with the Bite Cell Count appearance of a bite having been removed, due to oxidative hemolysis) in a biological specimen .

C98710 BKVVLD BKV Viral Load A measurement of the BK virus viral load in a BK Virus Viral Load Measurement biological specimen.

C74605 BLAST Blasts A measurement of the blast cells in a biological Blast Count specimen.

C64487 BLASTLE Blasts/ A relative measurement (ratio or percentage) of the Blast To Leukocyte Ratio Leukocytes blasts to leukocytes in a biological specimen.

C74630 BLASTLM Leukemic Blasts; A measurement of the leukemic blasts (lymphoblasts Leukemic Blast Count Leukemic that remain in an immature state even when outside the Lymphoblasts; bone marrow) in a biological specimen. Immunoblastic Lymphocytes

C74641 BLSTLMLY Leukemic A relative measurement (ratio or percentage) of the Leukemic Blast to Lymphocyte Blasts/ leukemic blasts (immature lymphoblasts) to mature Ratio Measurement Lymphocytes lymphocytes in a biological specimen.

C98761 BLSTMBCE Myeloblasts/ A relative measurement (ratio or percentage) of the Myeloblast to Total Cell Ratio Total Cells myeloblasts to total cells in a biological specimen (for Measurement example a bone marrow specimen).

C98752 BLSTMGK Megakaryoblasts A measurement of the megakaryoblasts in a biological Megakaryoblast Cell Count specimen.

C98753 BLSTMKCE Megakaryoblasts A relative measurement (ratio or percentage) of the Megakaryoblast to Total Cell Ratio /Total Cells megakaryoblasts to total cells in a biological specimen Measurement (for example a bone marrow specimen).

C98764 BLSTNMCE Normoblasts/ A relative measurement (ratio or percentage) of the Normoblast to Total Cell Ratio Total Cells normoblasts to total cells in a biological specimen Measurement (for example a bone marrow specimen).

C98870 BLSTPNCE Pronormoblasts/ A relative measurement (ratio or percentage) of the Pronormoblast to Total CellRatio Total Cells pronormoblasts to total cells in a biological specimen Measurement (for example a bone marrow specimen).

C100419 BLSTRSID Ringed A measurement of the ringed sideroblasts (abnormal Ringed Sideroblast Measurement Sideroblasts nucleated erythroblasts with a large number of iron deposits in the perinuclear mitochondria, forming a ring around the nucleus) in a biological specimen.

C100418 BLSTSID Sideroblast A measurement of the sideroblasts (nucleated Sideroblast Measurement erythroblasts with iron granules in the cytoplasm) in a biological specimen.

C74735 BNP Brain Natriuretic A measurement of the brain (B-type) natriuretic Brain Natriuretic Peptide Peptide; B-Type peptide in a biological specimen. Measurement Natriuretic Peptide

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 133 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C65047 - LBTESTCD - Laboratory Test Code Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C82032 BNPPRO ProB-type A measurement of the proB-type natriuretic peptide in ProB-Type Natriuretic Peptide Natriuretic a biological specimen. Measurement Peptide; proBNP; Pro-Brain Natriuretic Peptide

C96610 BNPPRONT N-Terminal A measurement of the N-terminal proB-type N-Terminal ProB-type Natriuretic ProB-type natriuretic peptide in a biological specimen. Peptide Measurement Natriuretic Peptide; NT proBNP II; N-terminal pro-Brain Natriuretic Peptide

C74692 BNZDZPN Benzodiazepine A measurement of any benzodiazepine class drug Benzodiazepine Measurement present in a biological specimen.

C75350 BNZLCGN Benzoylecgonine A measurement of the benzoylecgonine in a biological Benzoylecgonine Measurement ; Cocaine specimen. Metabolite

C74634 BTECERBC Bite A relative measurement (ratio or percentage) of bite Bite Cell to Erythrocyte Ratio Cells/ cells (erythrocytes with the appearance of a bite having Measurement Erythrocytes been removed, due to oxidative hemolysis) to all erythrocytes in a biological specimen .

C100426 BTP Beta-Trace A measurement of the beta-trace protein in a Beta-Trace Protein Measurement Protein biological specimen.

C61019 BUN Blood Urea A measurement of the urea nitrogen in a blood Blood Urea Nitrogen Measurement Nitrogen specimen.

C74753 BUNCREAT BUN/Creatinine A relative measurement (ratio or percentage) (ratio) of Blood Urea Nitrogen To Creatinine the blood urea nitrogen (BUN) to the creatinine in a Ratio Measurement biological specimen.

C74701 BURRCE Burr Cells; A measurement of the Burr cells (erythrocytes Burr Cell Count Keratocytes characterized by the presence of small, blunt projections evenly distributed across the cell surface) in a biological specimen.

C80173 C1QAB Complement A measurement of the complement C1q antibody in a Complement C1q Antibody C1q Antibody biological specimen. Measurement

C80174 C3 Complement C3 A measurement of the complement C3 in a biological Complement C3 Measurement specimen.

C80175 C3A Complement A measurement of the complement C3a in a biological Complement C3a Measurement C3a; ASP, specimen. Complement C3 DesArg, Acetylation-stim ulating Protein

C80176 C3B Complement A measurement of the complement C3b in a biological Complement C3b Measurement C3b specimen.

C80177 C4 Complement C4 A measurement of the complement C4 in a biological Complement C4 Measurement specimen.

C80178 C4A Complement C4a A measurement of the complement C4a in a biological Complement C4a Measurement specimen.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 134 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C65047 - LBTESTCD - Laboratory Test Code Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C80179 C5A Complement C5a A measurement of the complement C5a in a biological Complement C5a Measurement specimen.

C64488 CA Calcium A measurement of the calcium in a biological Calcium Measurement specimen.

C81981 CA125AG Cancer Antigen A measurement of the cancer antigen 125 in a Cancer Antigen 125 Measurement 125 biological specimen.

C81982 CA19_9AG Cancer Antigen A measurement of the cancer antigen 19-9 in a Cancer Antigen 19-9 Measurement 19-9 biological specimen.

C74702 CABOT Cabot Rings A measurement of the Cabot rings (red-purple staining, Cabot Ring Count threadlike, ring or figure 8 shaped filaments in an erythrocyte) in a biological specimen.

C96589 CACLR Calcium A measurement of the volume of serum or plasma that Calcium Clearance Measurement Clearance would be cleared of calcium by excretion of urine for a specified unit of time (e.g. one minute).

C79439 CACREAT Calcium/ A relative measurement (ratio or percentage) of the Calcium to Creatinine Ratio Creatinine calcium to creatinine in a biological specimen. Measurement

C81948 CAION Calcium, Ionized A measurement of the ionized calcium in a biological Ionized Calcium Measurement specimen.

C82005 CALPRO Calprotectin A measurement of the calprotectin in a biological Calprotectin Measurement specimen.

C74689 CANNAB Cannabinoids A measurement of any cannabinoid class drug present Cannabinoid Drug Class in a biological specimen. Measurement

C96591 CARBXHGB Carboxyhemoglo A measurement of the carboxyhemoglobin in a Carboxyhemoglobin Measurement bin biological specimen.

C74682 CARNIT Carnitine A measurement of the total carnitine in a biological Total Carnitine Measurement specimen.

C92288 CARNITAT Carnitine Acetyl A measurement of the carnitine acetyl transferase in a Carnitine Acetyl Transferase Transferase biological specimen. Measurement

C74677 CARNITF Carnitine, Free A measurement of the free carnitine in a biological Free Carnitine Measurement specimen.

C74763 CASTS Casts A statement that indicates casts were looked for and Cast Present Or Absent not found in a biological specimen.

C96590 CASULPH Calcium Sulphate A measurement of the calcium sulphate in a biological Calcium Sulphate Measurement specimen.

C80172 CBB Complement Bb A measurement of the complement Bb in a biological Complement Bb Measurement specimen.

C74850 CCK Cholecystokinin; A measurement of the cholecystokinin hormone in a Cholecystokinin Measurement Pancreozymin biological specimen.

C96595 CCPAB Cyclic A measurement of the cyclic citrullinated peptide Cyclic Citrullinated Peptide Citrullinated antibody in a biological specimen. Antibody Measurement Peptide Antibody

C74606 CD19 CD19 A count of the CD19 B cells per unit of a biological CD19 Expressing B Cell Count specimen.

C74635 CD19LY CD19/ A relative measurement (ratio or percentage) of CD19 CD19 B Cell to Lymphocyte Ratio Lymphocytes B cells to all lymphocytes in a biological specimen. Measurement

C74607 CD3 CD3 A count of the CD3 T cells per unit of a biological CD3 Expressing T Cell Count specimen.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 135 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C65047 - LBTESTCD - Laboratory Test Code Codelist extensible: Yes

CDISC NCI CodeCDISC Submission Value SynonymCDISC DefinitionNCI Preferred Term

C74636 CD3LYCD3/ A relative measurement (ratio or percentage) of CD3 T CD3 T Cell to Lymphocyte Ratio Lymphocytes cells to all lymphocytes in a biological specimen. Measurement

C74608CD4CD4A count of the CD4 T cells per unit of a biological CD4 Expressing T Cell Count specimen.

C82006 CD40CD40A measurement of the CD40 in a biological specimen.CD40 Measurement

C82007 CD40LCD40 LigandA measurement of the CD40 ligand in a biological CD40 Ligand Measurement specimen.

C74637 CD4CD8CD4/CD8A relative measurement (ratio or percentage) of CD4 T CD4 T Cell to CD8 T Cell Ratio cells to the CD8 T cells in a biological specimen. Measurement

C74638CD4LYCD4/ A relative measurement (ratio or percentage) of CD4 T CD4 T Cell to Lymphocyte Ratio Lymphocytes cells to all lymphocytes in a biological specimen. Measurement

C74609CD8CD8A count of the CD8 T cells per unit of a biological CD8 Expressing T Cell Count specimen.

C74639 CD8LYCD8/ A relative measurement (ratio or percentage) of CD8 T CD8 T Cell to Lymphocyte Ratio Lymphocytes cells to all lymphocytes in a biological specimen. Measurement

C101016CDTCarbohydrate-De A measurement of transferrin with a reduced number Carbohydrate-Deficient Transferrin ficient of carbohydrate moieties in a biological specimen. Measurement Transferrin

C81983 CEACarcinoembryoni A measurement of the carcinoembryonic antigen in a Carcinoembryonic Antigen c Antigen biological specimen. Measurement

C96592CECCirculating A measurement of the circulating endothelial cells in a Circulating Endothelial Cell Count Endothelial Cells biological specimen.

C96672 CELLSIMImmature CellsA measurement of the total immature cells in a blood Immature Cell Count specimen.

C100423 CH50Complement A measurement of the complement required to lyse 50 CH50 Measurement CH50; Total percent of red blood cells in a biological specimen. Hemolytic Complement; CH50

C61032CHOLCholesterol; A measurement of the cholesterol in a biological Serum Total Cholesterol Total specimen. Measurement Cholesterol

C80171 CHOLHDLCholesterol/ A relative measurement (ratio or percentage) of total Cholesterol to HDL-Cholesterol HDL-Cholestero cholesterol to high-density lipoprotein cholesterol Ratio Measurement l (HDL-C) in a biological specimen.

C92289CHOLINESCholinesteraseA measurement of the cholinesterase in a biological Cholinesterase Measurement specimen.

C92248 CITRATECitrateA measurement of the citrate in a biological specimen.Citrate Measurement

C64489 CKCreatine KinaseA measurement of the total creatine kinase in a Creatine Kinase Measurement biological specimen.

C64490 CKBBCreatine Kinase A measurement of the homozygous B-type creatine Creatine Kinase BB Measurement BB kinase in a biological specimen.

C79466 CKBBCKCreatine Kinase A relative measurement (ratio or percentage) of the Creatine Kinase BB to Total Creatine BB/Total BB-type creatine kinase to total creatine kinase in a Kinase Ratio Measurement Creatine Kinase biological specimen.

C64491CKMBCreatine Kinase A measurement of the heterozygous MB-type creatine MB kinase in a biological specimen.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 136 of 431 -A> CDISC Controlled Terminology SDTM - 2012-03-23 C65047 - LBTESTCD - Laboratory Test Code Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C79441 CKMBCK Creatine Kinase A relative measurement (ratio or percentage) of the Creatine Kinase MB to Total MB/Total MB-type creatine kinase to total creatine kinase in a Creatine Kinase Ratio Measurement Creatine Kinase biological specimen.

C64494 CKMM Creatine Kinase A measurement of the homozygous M-type creatine Creatine Kinase MM Measurement MM kinase in a biological specimen.

C79442 CKMMCK Creatine Kinase A relative measurement (ratio or percentage) of the Creatine Kinase MM to Total MM/Total MM-type creatine kinase to total creatine kinase in a Creatine Kinase Ratio Measurement Creatine Kinase biological specimen.

C64495 CL Chloride A measurement of the chloride in a biological Chloride Measurement specimen.

C96594 CLARITY Clarity A measurement of the transparency of a biological Clarity Measurement specimen.

C79440 CLCREAT Chloride/ A relative measurement (ratio or percentage) of the Chloride to Creatinine Ratio Creatinine chloride to creatinine in a biological specimen. Measurement

C74848 CLCTONN Calcitonin A measurement of the calcitonin hormone in a Calcitonin Measurement biological specimen.

C74849 CLCTRIOL Calcitriol A measurement of the calcitriol hormone in a Calcitriol Measurement biological specimen.

C96596 CMVIGGAB Cytomegalovirus A measurement of the cytomegalovirus IgG antibody Cytomegalovirus IgG Antibody IgG Antibody in a biological specimen. Measurement

C96597 CMVIGMAB Cytomegalovirus A measurement of the cytomegalovirus IgM antibody Cytomegalovirus IgM Antibody IgM Antibody in a biological specimen. Measurement

C98716 CMVVLD CMV Viral Load A measurement of the cytomegalovirus viral load in a Cytomegalovirus Viral Load biological specimen. Measurement

C64545 CO2 Carbon Dioxide A measurement of the carbon dioxide gas in a Carbon Dioxide Measurement biological specimen.

C74690 COCAINE Cocaine A measurement of the cocaine present in a biological Cocaine Measurement specimen.

C74877 CODEINE Codeine A measurement of the codeine present in a biological Codeine Measurement specimen.

C64546 COLOR Color A measurement of the color of a biological specimen. Color Assessment

C88113 CORTFR Cortisol, Free A measurement of the free, unbound cortisol in a Free Cortisol Measurement biological specimen.

C74781 CORTISOL Cortisol; Total A measurement of the cortisol in a biological Cortisol Measurement Cortisol specimen.

C92249 COTININE Cotinine A measurement of the cotinine in a biological Cotinine Measurement specimen.

C74736 CPEPTIDE C-peptide A measurement of the C (connecting) peptide of C-peptide Measurement insulin in a biological specimen.

C92432 CPNIGAAB Chlamydia A measurement of the Chlamydia pneumoniae IgA Chlamydia pneumoniae IgA Antibody pneumoniae IgA antibody in a biological specimen. Measurement Antibody

C92433 CPNIGMAB Chlamydia A measurement of the Chlamydia pneumoniae IgM in a Chlamydia pneumoniae IgM pneumoniae IgM biological specimen. Antibody Measurement Antibody

C64547 CREAT Creatinine A measurement of the creatinine in a biological Creatinine Measurement specimen.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 137 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C65047 - LBTESTCD - Laboratory Test Code Codelist extensible: Yes

CDISC NCI CodeCDISC Submission Value SynonymCDISC DefinitionNCI Preferred Term

C25747 CREATCLRCreatinine A measurement of the volume of serum or plasma that Creatinine Clearance Clearance would be cleared of creatinine by excretion of urine for a specified unit of time (e.g. one minute).

C74703CRENCECrenated Cells; A measurement of the Burr cells (erythrocytes Crenated Cell Measurement Echinocytes characterized by the presence of multiple small, sharp projections evenly distributed across the cell surface) in a biological specimen.

C74851 CRHCorticotropin A measurement of the corticotropin releasing Corticotropin Releasing Hormone Releasing hormone in a biological specimen. Measurement Hormone; Corticotropin Releasing Factor

C100432 CRLPLSMNCeruloplasmin; A measurement of ceruloplasmin in a biological Ceruloplasmin Measurement Caeruloplasmin specimen.

C64548 CRPC Reactive A measurement of the C reactive protein in a C-Reactive Protein Measurement Protein biological specimen.

C79434 CRTRONECorticosteroneA measurement of corticosterone in a biological Corticosterone Measurement specimen.

C74673 CRYSTALSCrystalsA statement that indicates crystals were looked for and Crystal Present Or Absent not found in a biological specimen.

C74762 CSBACTBacterial CastsA measurement of the bacterial casts present in a Bacterial Cast Measurement biological specimen.

C96588 CSBROADBroad CastsA measurement of the broad casts in a biological Broad Casts Measurement specimen.

C74764 CSCELLCellular CastsA measurement of the cellular (white blood cell, red Cellular Cast Measurement blood cell, epithelial and bacterial) casts present in a biological specimen.

C74779CSEPIEpithelial CastsA measurement of the epithelial cell casts present in a Epithelial-Cast Measurement biological specimen.

C74766 CSFATFatty CastsA measurement of the fatty casts present in a Fatty Cast Measurement biological specimen.

C74768 CSGRANGranular CastsA measurement of the granular (coarse and fine) casts Granular Cast Measurement present in a biological specimen.

C74765 CSGRANCGranular Coarse A measurement of the coarse granular casts present in Coarse Granular Cast Measurement Casts a biological specimen.

C74769 CSGRANFGranular Fine A measurement of the fine granular casts present in a Granular Fine Cast Measurement Casts biological specimen.

C74770 CSHYALHyaline CastsA measurement of the hyaline casts present in a Hyaline Cast Measurement biological specimen.

C74771 CSMIXMixed CastsA measurement of the mixed (the cast contains a Mixed Cast Count mixture of cell types) casts present in a biological specimen.

C74772CSRBCRBC CastsA measurement of the red blood cell casts present in a Red Blood Cell Cast Measurement biological specimen.

C74776 CSUNCLAUnclassified A measurement of the unclassifiable casts present in a Unclassified Cast Measurement Casts biological specimen.

C74777 CSWAXWaxy CastsA measurement of the waxy casts present in a biological specimen.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 138 of 431 -A> CDISC Controlled Terminology SDTM - 2012-03-23 C65047 - LBTESTCD - Laboratory Test Code Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C74778 CSWBC WBC Casts A measurement of the white blood cell casts present in White Blood Cell Cast Measurement a biological specimen.

C96593 CTC Circulating A measurement of the circulating tumor cells in a Circulating Tumor Cell Count Tumor Cells biological specimen.

C80160 CTOT Complement A measurement of the total complement in a Complement Measurement Total biological specimen.

C100464 CTRIGAAB Chlamydia A measurement of the Chlamydia trachomatis IgA Chlamydia trachomatis IgA Antibody trachomatis IgA antibody in a biological specimen. Measurement Antibody

C100466 CTRIGGAB Chlamydia A measurement of the Chlamydia trachomatis IgG Chlamydia trachomatis IgG Antibody trachomatis IgG antibody in a biological specimen. Measurement Antibody

C100465 CTRIGMAB Chlamydia A measurement of the Chlamydia trachomatis IgM Chlamydia trachomatis IgM Antibody trachomatis IgM antibody in a biological specimen. Measurement Antibody

C82038 CTXI Type I Collagen A measurement of the type I collagen C-telopeptides Type I Collagen C-Telopeptide C-Telopeptides; in a biological specimen. Measurement Type I Collagen X-linked C-telopeptide

C82040 CTXII Type II Collagen A measurement of the type II collagen C-telopeptides Type II Collagen C-Telopeptide C-Telopeptides in a biological specimen. Measurement

C100431 CXCR3 Chemokine A measurement of the CXCR3, chemokine (C-X-C Chemokine Receptor CXCR3 (C-X-C Motif) motif) receptor 3, in a biological specimen. Measurement Receptor 3; GPR9, CD183, CXCR3

C74912 CYACIDU Acid Urate A measurement of the ammonium acid urate crystals Acid Urate Crystal Measurement Crystals present in a biological specimen.

C74758 CYAMMBIU Ammonium A measurement of the ammonium biurate crystals Urine Ammonium Biurate Crystal Biurate Crystals; present in a biological specimen. Measurement Ammonium Urate

C74759 CYAMMOX Ammonium A measurement of the ammonium oxalate crystals Urine Ammonium Oxalate Crystal Oxalate Crystals present in a urine specimen. Measurement

C74665 CYAMORPH Amorphous A measurement of the amorphous (Note: phosphate or Amorphous Crystal Measurement Crystals urate, depending on pH) crystals present in a biological specimen.

C92243 CYAMPPH Amorphous A measurement of the amorphous phosphate crystals Amorphous Phosphate Crystals Phosphate in a biological specimen. Measurement Crystals

C92244 CYAMPURT Amorphous A measurement of the amorphous urate crystals in a Amorphous Urate Crystals Urate Crystals biological specimen. Measurement

C74668 CYBILI Bilirubin A measurement of the bilirubin crystals present in a Bilirubin Crystal Measurement Crystals biological specimen.

C74669 CYCACAR Calcium A measurement of the calcium carbonate crystals Calcium Carbonate Crystal Carbonate present in a biological specimen. Measurement Crystals

C74670 CYCAOXA Calcium Oxalate A measurement of the calcium oxalate crystals present Calcium Oxalate Crystal Crystals in a biological specimen. Measurement

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 139 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C65047 - LBTESTCD - Laboratory Test Code Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C74671 CYCAPHOS Calcium A measurement of the calcium phosphate crystals Calcium Phosphate Crystal Phosphate present in a biological specimen. Measurement Crystals

C74672 CYCHOL Cholesterol A measurement of the cholesterol crystals present in a Cholesterol Crystal Measurement Crystals biological specimen.

C74674 CYCYSTIN Cystine Crystals A measurement of the cystine crystals present in a Cystine Crystal Measurement biological specimen.

C74754 CYHIPPAC Hippuric Acid A measurement of the hippuric acid crystals present in Hippuric Acid Crystal Measurement Crystals a biological specimen.

C74680 CYLEUC Leucine Crystals A measurement of the leucine crystals present in a Leucine Crystal Measurement biological specimen.

C74681 CYMSU Monosodium A measurement of the monosodium urate crystals Monosodium Urate Crystal Urate Crystals present in a biological specimen. Measurement

C81951 CYSTARCH Starch Crystals A measurement of the starch crystals in a biological Starch Crystal Measurement specimen.

C92290 CYSTATC Cystatin C A measurement of the cystatin C in a biological Cystatin C Measurement specimen.

C74755 CYSULFA Sulfa Crystals A measurement of the sulfa crystals present in a Sulfa Crystal Measurement biological specimen.

C74756 CYTRPHOS Triple Phosphate A measurement of the triple phosphate crystals present Triple Phosphate Crystal Crystals in a biological specimen. Measurement

C74683 CYTYRO Tyrosine A measurement of the triple phosphate crystals present Tyrosine Crystal Measurement Crystals in a biological specimen.

C74757 CYUNCLA Unclassified A measurement of the unclassifiable crystals present Unclassified Crystal Measurement Crystals in a biological specimen.

C74684 CYURIAC Uric Acid A measurement of the uric acid crystals present in a Uric Acid Crystal Measurement Crystals biological specimen.

C82621 DDIMER D-Dimer A measurement of the d-dimers in a biological D-Dimer Measurement specimen.

C74852 DHEA Dehydroepiandro A measurement of the dehydroepiandrosterone Dehydroepiandrosterone sterone; hormone in a biological specimen. Measurement Dehydroisoandro sterone

C96629 DHEAS Dehydroepiandro A measurement of the sulfated Sulfated DHEA Measurement sterone Sulfate; Dehydroepiandrosterone in a biological specimen. DHEA-S; sDHEA; DHEA Sulfate

C101017 DHPG 3,4-Dihydroxyph A measurement of the catecholamine metabolite, 3,4-Dihydroxyphenylglycol enylglycol; 3.4 3,4-Dihydroxyphenylglycol in a biological specimen. Measurement Dihydroxyphenyl glycol

C74853 DHT Dihydrotestoster A measurement of the dihydrotestosterone hormone in Dihydrotestosterone Measurement one; a biological specimen. Androstanalone

C74878 DIHYDCDN Dihydrocodeine A measurement of the dihydrocodeine present in a Dihydrocodeine Measurement biological specimen.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 140 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C65047 - LBTESTCD - Laboratory Test Code Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C81973 DNAAB Anti-DNA A measurement of the anti-DNA antibodies in a Anti-DNA Antibody Measurement Antibodies; biological specimen. Anti-ds-DNA Antibodies

C100463 DNASEBAB DNase-B A measurement of Dnase-B antibody in a biological DNase-B Antibody Measurement Antibody; specimen. Anti-Dnase B

C74610 DOHLE Dohle Bodies A measurement of the Dohle bodies (blue-gray, Dohle Body Measurement basophilic, leukocyte inclusions located in the peripheral cytoplasm of neutrophils) in a biological specimen.

C74854 DOPAMINE Dopamine A measurement of the dopamine hormone in a Dopamine Measurement biological specimen.

C79443 DPD Deoxypyridinoli A measurement of the deoxypyridinoline in a Deoxypyridinoline Measurement ne biological specimen.

C79444 DPDCREAT Deoxypyridinoli A relative measurement (ratio or percentage) of the Deoxypyridinoline to Creatinine ne/Creatinine deoxypyridinoline to creatinine in a biological Ratio Measurement specimen.

C96696 DRVVT Dilute Russell's A measurement of the time it takes a plasma sample to Dilute Russell's Viper Venom Time Viper Venom clot after adding dilute Russell's viper venom. Measurement Time

C100441 DTPACLR DTPA Clearance A measurement of the volume of serum or plasma that Diethylene Triamine Pentaacetic would be cleared of Diethylenetriamine pentaacetate Acid Clearance (DTPA) through its excretion for a specified unit of time.

C96600 EBCIGGAB Epstein-Barr A measurement of the Epstein-Barr capsid IgG Epstein-Barr Capsid IgG Antibody Capsid IgG antibody in a biological specimen. Measurement Antibody

C96601 EBCIGMAB Epstein-Barr A measurement of the Epstein-Barr capsid IgM Epstein-Barr Capsid IgM Antibody Capsid IgM antibody in a biological specimen. Measurement Antibody

C96602 EBEAG Epstein-Barr A measurement of the Epstein-Barr early antigen in a Epstein-Barr Early Antigen Early Antigen biological specimen. Measurement

C96603 EBNAB Epstein-Barr A measurement of the Epstein-Barr nuclear antibody in Epstein-Barr Nuclear Antibody Nuclear a biological specimen. Measurement Antibody

C96604 EBNAG Epstein-Barr A measurement of the Epstein-Barr nuclear antigen in Epstein-Barr Nuclear Antigen Nuclear Antigen a biological specimen. Measurement

C98721 EBVVLD EBV Viral Load A measurement of the Epstein-Barr virus viral load in a Epstein-Barr Virus Viral Load biological specimen. Measurement

C96598 ECCENTCY Eccentrocytes A measurement of the eccentrocytes (erythrocytes in Eccentrocyte Count which the hemoglobin is localized to a particular portion of the cell, noticeable as localized staining) in a biological specimen.

C100422 ECT Ecarin Clotting A measurement of the activity of thrombin inhibitors Ecarin Clotting Time Measurement Time in a biological specimen based on the generation of meizothrombin.

C100440 EDTACLR EDTA Clearance A measurement of the volume of serum or plasma that EDTA Clearance would be cleared of Ethylenediamine tetraacetic acid (EDTA) through its excretion for a specified unit of time.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 141 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C65047 - LBTESTCD - Laboratory Test Code Codelist extensible: Yes

CDISC NCI CodeCDISC Submission Value SynonymCDISC DefinitionNCI Preferred Term

C82009 EGFEpidermal A measurement of the epidermal growth factor in a Epidermal Growth Factor Growth Factor biological specimen. Measurement

C82028ELA1Pancreatic A measurement of the pancreatic elastase 1 in a Pancreatic Elastase Measurement Elastase 1 biological specimen.

C82029 ELA1PMNPancreatic A measurement of the polymorphonuclear pancreatic Polymorphonuclear Pancreatic Elastase 1, elastase 1 in a biological specimen. Elastase Measurement Polymorphonucl ear

C82026ELA2Neutrophil A measurement of the neutrophil elastase in a Neutrophil Elastase Measurement Elastase biological specimen.

C82027 ELA2PMNNeutrophil A measurement of the polymorphonuclear neutrophil Polymorphonuclear Neutrophil Elastase, elastase in a biological specimen. Elastase Measurement Polymorphonucl ear

C64549ELLIPCYElliptocytes; A measurement of the elliptically shaped erythrocytes Elliptocyte Count Ovalocytes in a biological specimen.

C82010 ENA78Epith A measurement of the epithelial neutrophil-activating Epithelial Neutrophil-Activating Neutrophil-Activ peptide in a biological specimen. Peptide 78 Measurement ating Peptide 78

C92270 ENAABAnti-ENA; A measurement of the extractable nuclear antigen Extractable Nuclear Antigen Extractable antibody in a biological specimen. Antibody Measurement Nuclear Antigen Antibody

C82008ENDOTH1Endothelin-1A measurement of the endothelin-1 in a biological Endothelin-1 Measurement specimen.

C82011 ENRAGEExtracell Newly A measurement of the extracellular newly identified Extracell Newly Ident RAGE Bind Ident RAGE Bind RAGE (receptor for advanced glycation end products) Protein Measurement Protein; S100 binding protein in a biological specimen. Calcium Binding Protein A12

C64550EOSEosinophilsA measurement of the eosinophils in a biological Eosinophil Count specimen.

C98720 EOSCEEosinophils/ A relative measurement (ratio or percentage) of the Eosinophils to Total Cell Ratio Total Cells eosinophils to total cells in a biological specimen (for Measurement example a bone marrow specimen).

C96673 EOSIMImmature A measurement of the immature eosinophils in a Immature Eosinophil Count Eosinophils biological specimen.

C96674 EOSIMLEImmature A relative measurement (ratio or percentage) of Immature Eosinophil to Leukocyte Eosinophils/ immature eosinophils to total leukocytes in a Ratio Measurement Leukocytes biological specimen.

C64604EOSLEEosinophils/ A relative measurement (ratio or percentage) of the Eosinophil To Leukocyte Ratio Leukocytes eosinophils to leukocytes in a biological specimen.

C84819 EOSMMEosinophilic A measurement of the eosinphilic metamyelocytes in a Eosinophilic Metamyelocyte Count Metamyelocytes biological specimen.

C84821 EOSMYLEosinophilic A measurement of the eosinophilic myelocytes in a Eosinophilic Myelocyte Count Myelocytes biological specimen.

C81952 EOTAXIN1Eotaxin-1; A measurement of the eotaxin-1 in a biological Eotaxin-1 Measurement Chemokine specimen. Ligand 11

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 142 of 431 -A> CDISC Controlled Terminology SDTM - 2012-03-23 C65047 - LBTESTCD - Laboratory Test Code Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C81953 EOTAXIN2 Eotaxin-2; A measurement of the eotaxin-2 in a biological Eotaxin-2 Measurement Chemokine specimen. Ligand 24

C81954 EOTAXIN3 Eotaxin-3; A measurement of the eotaxin-3 in a biological Eotaxin-3 Measurement Chemokine specimen. Ligand 26

C64605 EPIC Epithelial Cells A measurement of the epithelial cells in a biological Epithelial Cell Count specimen.

C79445 EPIN Epinephrine; A measurement of the epinephrine hormone in a Epinephrine Measurement Adrenaline biological specimen.

C74698 EPIROCE Round Epithelial A measurement of the round epithelial cells present in Round Epithelial Cell Count Cells a biological specimen.

C74773 EPISQCE Squamous A measurement of the squamous epithelial cells Squamous Epithelial Cell Count Epithelial Cells present in a biological specimen.

C74774 EPISQTCE Squamous A measurement of the squamous transitional epithelial Squamous Transitional Epithelial Transitional cells present in a biological specimen. Cell Count Epithelial Cells; Epithelial Cells

C92251 EPITCE Transitional A measurement of the transitional epithelial cells Transitional Epithelial Cells Epithelial Cells present in a biological specimen. Measurement

C74775 EPITUCE Tubular A measurement of the tubular epithelial cells present Tubular Epithelial Cell Count Epithelial Cells; in a biological specimen. Renal Tubular Epithelial Cells

C74855 EPO Erythropoietin; A measurement of the erythropoietin hormone in a Erythropoietin Measurement Hematopoietin biological specimen.

C74611 ESR Erythrocyte The distance (e.g. millimeters) that red blood cells Erythrocyte Sedimentation Rate Sedimentation settle in unclotted blood over a specified unit of time Measurement Rate; Biernacki (e.g. one hour). Reaction

C74782 ESTRDIOL Estradiol; A measurement of the estradiol in a biological Estradiol Measurement Oestradiol specimen.

C74856 ESTRIOL Estriol; Oestriol A measurement of the estriol hormone in a biological Estriol Measurement specimen.

C81963 ESTRIOLF Estriol, Free A measurement of the free estriol in a biological Free Estriol Measurement specimen.

C74857 ESTRONE Estrone; A measurement of the estrone hormone in a biological Estrone Measurement Oestrone specimen.

C74693 ETHANOL Ethanol; Alcohol A measurement of the ethanol present in a biological Ethanol Measurement specimen.

C82012 FABP1 Fatty Acid A measurement of the fatty acid binding protein 1 in a Fatty Acid Binding Protein 1 Binding Protein biological specimen. Measurement 1

C96626 FACTII Factor II; A measurement of the Factor II in a biological Prothrombin Measurement Prothrombin specimen.

C81959 FACTIII Factor III; Tissue A measurement of the factor III in a biological Factor III Measurement Factor, CD142 specimen.

C98725 FACTIX Factor IX A measurement of the factor IX in a biological Factor IX Measurement specimen.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 143 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C65047 - LBTESTCD - Laboratory Test Code Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C98726 FACTV Factor V A measurement of the factor V in a biological Factor V Measurement specimen.

C81960 FACTVII Factor VII A measurement of the factor VII in a biological Factor VII Measurement specimen.

C81961 FACTVIII Factor VIII A measurement of the factor VIII in a biological Factor VIII Measurement specimen.

C98799 FACTVW von Willebrand A measurement of the von Willebrand factor in a von Willebrand Factor Measurement Factor biological specimen.

C98727 FACTX Factor X A measurement of the factor X in a biological Factor X Measurement specimen.

C96648 FAT Fat A measurement of the fat in a biological specimen. Fat Measurement

C80200 FATACFR Free Fatty Acid; A measurement of the total non-esterified fatty acids Non-esterified Fatty Acids Non-Esterified in a biological specimen. Measurement Fatty Acid, Free

C80206 FATACFRS Free Fatty Acid, A measurement of the saturated non-esterified fatty Saturated Non-esterified Fatty Acids Saturated; acids in a biological specimen. Measurement Non-esterified Fatty Acid, Saturated

C80209 FATACFRU Free Fatty Acid, A measurement of the unsaturated non-esterified fatty Unsaturated Non-esterified Fatty Unsaturated; acids in a biological specimen. Acids Measurement Non-esterified Fatty Acid, Unsaturated

C81947 FATBODOV Fat Bodies, Oval A measurement of the oval-shaped fat bodies, usually Oval Fat Body Measurement renal proximal tubular cells with lipid aggregates in the cytoplasm, in a biological specimen.

C98728 FATDROP Fat Droplet A measurement of the triglyceride aggregates within a Fat Droplet Measurement biological specimen.

C82013 FDP Fibrin A measurement of the fibrin degradation products in a Fibrin Degradation Products Degradation biological specimen. Measurement Products

C74737 FERRITIN Ferritin A measurement of the ferritin in a biological Ferritin Measurement specimen.

C96650 FGF23 Fibroblast A measurement of the fibroblast growth factor 23 in a Fibroblast Growth Factor 23 Growth Factor biological specimen. Measurement 23; Phosphatonin

C82014 FGFBF Fibroblast A measurement of the basic form of fibroblast growth Fibroblast Growth Factor Basic Growth Factor factor in a biological specimen. Form Measurement Basic Form; FGF2

C64606 FIBRINO Fibrinogen A measurement of the fibrinogen in a biological Fibrinogen Measurement specimen.

C74678 FRUCT Fructosamine; A measurement of the fructosamine in a biological Fructosamine Measurement Glycated Serum specimen. Protein

C74783 FSH Follicle A measurement of the follicle stimulating hormone Follicle Stimulating Hormone Stimulating (FSH) in a biological specimen. Measurement Hormone

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 144 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C65047 - LBTESTCD - Laboratory Test Code Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C80184 G6PD Glucose-6-Phos A measurement of the glucose-6-phosphate Glucose-6-Phosphate phate dehydrogenase in a biological specimen. Dehydrogenase Measurement Dehydrogenase

C82015 GAD1 Glutamic Acid A measurement of the glutamic acid decarboxylase 1 Glutamic Acid Decarboxylase 1 Decarboxylase 1; in a biological specimen. Measurement Glutamic Acid Decarboxylase 67

C82016 GAD2 Glutamic Acid A measurement of the glutamic acid decarboxylase 2 Glutamic Acid Decarboxylase 2 Decarboxylase 2; in a biological specimen. Measurement Glutamic Acid Decarboxylase 65

C82017 GAD2AB Glutamic Acid A measurement of the glutamic acid decarboxylase 2 Glutamic Acid Decarboxylase 2 Decarboxylase 2 antibody in a biological specimen. Antibody Measurement Antibody; Glutamic Acid Decarboxylase 65 Antibody

C96653 GADAB Glutamic Acid A measurement of the glutamic acid decarboxylase Glutamic Acid Decarboxylase Decarboxylase antibody in a biological specimen. Antibody Measurement Antibody; GAD Antibody

C80182 GALANIN Galanin A measurement of the galanin in a biological Galanin Measurement specimen.

C74858 GASTRIN Gastrin A measurement of the gastrin hormone in a biological Gastrin Measurement specimen.

C82018 GCSF Granulocyte A measurement of the granulocyte colony stimulating Granulocyte Colony Stimulating Colony factor in a biological specimen. Factor Measurement Stimulating Factor

C90505 GFR Glomerular A kidney function test that measures the fluid volume Glomerular Filtration Rate Filtration Rate that is filtered from the kidney glomeruli to the Bowman's capsule per unit of time.

C98734 GFRBSA Glomerular A measurement of the glomerular filtration rate Glomerular Filtration Rate Adjusted Filtration Rate adjusted for body size. for BSA Adj for BSA

C100450 GFRBSB2M GFR from B-2 A measurement of the glomerular filtration rate (GFR) Glomerular Filtration Rate from B-2 Microglobulin based on the clearance of beta-2 microglobulin after Microglobulin Adjusted for BSA Adj for BSA adjusting it for the body surface area. Measurement

C100449 GFRBSBTP GFR from A measurement of the glomerular filtration rate (GFR) Glomerular Filtration Rate from Beta-Trace based on the clearance of beta-trace protein after Beta-Trace Protein Adjusted for BSA Protein Adj for adjusting it for the body surface area. Measurement BSA

C98735 GFRBSCRT GFR from An estimation of the glomerular filtration rate adjusted Glomerular Filtration Rate from Creatinine for body size based on creatinine. Creatinine Adjusted for BSA Adjusted for BSA

C98736 GFRBSCYC GFR from An estimation of the glomerular filtration rate adjusted Glomerular Filtration Rate from Cystatin C for body size based on cystatin C. Cystatin C Adjusted for BSA Adjusted for BSA

C64847 GGT Gamma Glutamyl A measurement of the gamma glutamyl transferase in a Gamma Glutamyl Transpeptidase Transferase biological specimen. Measurement

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 145 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C65047 - LBTESTCD - Laboratory Test Code Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C79446 GGTCREAT Gamma Glutamyl A relative measurement (ratio or percentage) of the Gamma Glutamyl Transferase to Transferase/ gamma glutamyl transferase to creatinine in a Creatinine Ratio Measurement Creatinine biological specimen.

C79448 GLDH Glutamate A measurement of the glutamate dehydrogenase in a Glutamate Dehydrogenase Dehydrogenase biological specimen. Measurement

C92252 GLOBA1 Alpha-1 A measurement of the proteins contributing to the Alpha-1 Globulin Measurement Globulin; alpha 1 fraction in a biological specimen. A1-Globulin

C92253 GLOBA1PT Alpha-1 A relative measurement (ratio or percentage) of Alpha-1 Globulin to Total Protein Globulin/Total alpha-1-fraction proteins to total proteins in a Ratio Measurement Protein biological specimen.

C92254 GLOBA2 Alpha-2 A measurement of the proteins contributing to the Alpha-2 Globulin Measurement Globulin; alpha 2 fraction in a biological specimen. A2-Globulin

C92255 GLOBA2PT Alpha-2 A relative measurement (ratio or percentage) of Alpha-2 Globulin to Total Protein Globulin/Total alpha-2-fraction proteins to total proteins in a Ratio Measurement Protein biological specimen.

C92256 GLOBB Beta Globulin A measurement of the proteins contributing to the beta Beta Globulin Measurement fraction in a biological specimen.

C92294 GLOBBPT Beta A relative measurement (ratio or percentage) of beta Beta Globulin to Total Protein Ratio Globulin/Total fraction proteins to total proteins in a biological Measurement Protein specimen.

C92257 GLOBG Gamma Globulin A measurement of the proteins contributing to the Gamma Globulin Measurement gamma fraction in a biological specimen.

C92295 GLOBGPT Gamma A relative measurement (ratio or percentage) of Gamma Globulin to Total Protein Globulin/Total gamma fraction proteins to total proteins in a Ratio Measurement Protein biological specimen.

C74738 GLOBUL Globulin A measurement of the globulin protein in a biological Globulin Protein Measurement specimen.

C80183 GLP1 Glucagon-Like A measurement of the total glucagon-like peptide-1 in Glucagon-like Peptide-1 Peptide-1; Total a biological specimen. Measurement Glucagon-Like Peptide-1

C80164 GLP1AC Glucagon-Like A measurement of the active form of glucagon-like Active Glucagon-like Peptide-1 Peptide-1, Active peptide-1 in a biological specimen. Measurement Form

C41376 GLUC Glucose A measurement of the glucose in a biological Plasma Glucose Measurement specimen.

C74859 GLUCAGON Glucagon A measurement of the glucagon hormone in a Glucagon Measurement biological specimen.

C96652 GLUCCLR Glucose A measurement of the glucose clearance in a Glucose Clearance Measurement Clearance biological specimen.

C79447 GLUCCRT Glucose/ A relative measurement (ratio or percentage) of the Glucose to Creatinine Ratio Creatinine glucose to creatinine in a biological specimen. Measurement

C74739 GLUTAM Glutamate; A measurement of the glutamate in a biological Glutamate Measurement Glutamic Acid specimen.

C100448 GLYCRLFR Free Glycerol; A measurement of the amount of unbound glycerol in a Free Glycerol Measurement Free Glycerin biological specimen.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 146 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C65047 - LBTESTCD - Laboratory Test Code Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C82019 GMCSF Granulocyte A measurement of the granulocyte macrophage colony Granulocyte Macrophage Colony Macrophage stimulating factor in a biological specimen. Stm Factor Measurement Colony Stm Factor

C74860 GNRH Gonadotropin A measurement of the gonadotropin releasing Gonadotropin Releasing Hormone Releasing hormone in a biological specimen. Measurement Hormone; Luteinising Hormone Releasing Hormone

C80186 GOLD Gold A measurement of the gold in a biological specimen. Gold Measurement

C96654 GRAN Granulocytes A measurement of the granulocytes in a biological Granulocyte Count specimen.

C98866 GRANCE Granulocytes/ A relative measurement (ratio or percentage) of the Granulocyte to Total CellRatio Total Cells granulocytes to total cells in a biological specimen Measurement (for example a bone marrow specimen).

C96675 GRANIM Immature A measurement of the total immature granulocytes in a Immature Granulocyte Count Granulocytes biological specimen.

C100445 GRANIMLE Immature A relative measurement (ratio or percentage) of the Immature Granulocytes to Granulocytes/ immature granulocytes to leukocytes in a biological Leukocytes Ratio Measurement Leukocytes specimen (for example a bone marrow specimen).

C74861 GRWHIH Growth A measurement of the growth hormone inhibiting Growth Hormone Inhibiting Hormone hormone in a biological specimen. Hormone Measurement Inhibiting Hormone; Somatostatin

C74862 GRWHRH Growth A measurement of the growth hormone releasing Growth Hormone Releasing Hormone hormone in a biological specimen. Hormone Measurement Releasing Hormone; Somatocrinin

C80185 GST Glutathione A measurement of the total glutathione-s-transferase Glutathione-S-Transferase S-Transferase, in a biological specimen. Measurement Total

C79433 GSTAL Alpha A measurement of the alpha form of glutathione Alpha Glutathione-S-Transferase Glutathione-S-Tr S-transferase in a biological specimen. Measurement ansferase

C80166 GSTALCRT Glutathione A relative measurement (ratio or percentage) of the Alpha Glutathione-S-Transferase to S-Transferase, alpha glutathione-S-transferase to creatinine in a Creatinine Ratio Measurement Alpha/Creat biological specimen.

C79435 GSTCREAT Glutathione-S-Tr A relative measurement (ratio or percentage) of the Glutathione-S-Transferase to ansferase/ glutathione S-transferase to creatinine in a biological Creatinine Ratio Measurement Creatinine specimen.

C79457 GSTMU Mu A measurement of the mu form of glutathione Mu Glutathione-S-Transferase Glutathione-S-Tr S-transferase in a biological specimen. Measurement ansferase

C79458 GSTMUCRT Mu A relative measurement (ratio or percentage) of the Mu Glutathione-S-Transferase to Glutathione-S-Tr mu gamma glutamyl transpeptidase to creatinine in a Creatinine Ratio Measurement ansferase/ biological specimen. Creatinine

C80203 GSTPI Glutathione A measurement of the Pi glutathione-s-transferase in a Pi Glutathione S-Transferase S-Transferase, Pi biological specimen. Measurement

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 147 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C65047 - LBTESTCD - Laboratory Test Code Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C80207 GSTTH Glutathione A measurement of the theta glutathione-s-transferase Theta Glutathione S-Transferase S-Transferase, in a biological specimen. Measurement Theta

C80165 GUSA Glucuronidase, A measurement of the alpha glucuronidase in a Alpha Glucuronidase Measurement Alpha biological specimen.

C80170 GUSB Glucuronidase, A measurement of the beta glucuronidase in a Beta Glucuronidase Measurement Beta biological specimen.

C92534 HAAB Hepatitis A Virus A measurement of the antibody reaction of a Hepatitis A Antibody Measurement Antibody biological specimen to the Hepatitis A virus.

C92271 HAABIGM Hepatitis A Virus A measurement of hepatitis A virus antibody IgM in a Hepatitis A Virus Antibody IgM Antibody IgM biological specimen. Measurement

C74604 HAIRYCE Hairy Cells A measurement of the hairy cells (b-cell lymphocytes Hairy Cell Count with hairy projections from the cytoplasm) in a biological specimen.

C74740 HAPTOG Haptoglobin A measurement of the haptoglobin protein in a Haptoglobin Protein Measurement biological specimen.

C98740 HASIGEAB Human A measurement of the human anti-sheep IgE antibodies Human Anti-Sheep IgE Antibody Anti-Sheep IgE in a biological specimen. Measurement Antibody

C98741 HASIGGAB Human A measurement of the human anti-sheep IgG Human Anti-Sheep IgG Antibody Anti-Sheep IgG antibodies in a biological specimen. Measurement Antibody

C98742 HASIGMAB Human A measurement of the human anti-sheep IgM Human Anti-Sheep IgM Antibody Anti-Sheep IgM antibodies in a biological specimen. Measurement Antibody

C92541 HAVVLD HAV Viral Load A measurement of the hepatitis A viral load in a Hepatitis A Viral Load Measurement biological specimen.

C64849 HBA1C Hemoglobin A measurement of the glycosylated hemoglobin in a Glycosylated Hemoglobin A1C biological specimen. Measurement

C96660 HBCAB Hepatitis B Virus A measurement of the hepatitis B virus core antibody Hepatitis B Virus Core Antibody Core Antibody in a biological specimen. Measurement

C96661 HBCIGMAB Hepatitis B Virus A measurement of the hepatitis B virus core IgM Hepatitis B Virus Core IgM Antibody Core IgM antibody in a biological specimen. Measurement Antibody

C96662 HBEAB Hepatitis B Virus A measurement of the hepatitis B e antibody in a Hepatitis B Virus e Antibody e Antibody biological specimen. Measurement

C96663 HBEAG Hepatitis B Virus A measurement of the hepatitis B e antigen in a Hepatitis B Virus e Antigen e Antigen biological specimen. Measurement

C74711 HBSAB Anti-HBs; A measurement of the surface antibody reaction of a Hepatitis B Surface Antibody HBsAb; Hepatitis biological specimen to the Hepatitis B virus. Measurement B Virus Surface Antibody

C64850 HBSAG HBsAg; Hepatitis A measurement of the surface antigen reaction of a Hepatitis B Virus Surface Antigen B Virus Surface biological specimen to the Hepatitis B virus. Measurement Antigen

C92542 HBVVLD HBV Viral Load A measurement of the hepatitis B viral load in a Hepatitis B Viral Load Measurement biological specimen.

C92535 HCAB Hepatitis C Virus A measurement of the antibody reaction of a Hepatitis C Antibody Measurement Antibody biological specimen to the Hepatitis C virus.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 148 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C65047 - LBTESTCD - Laboratory Test Code Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C64851 HCG Choriogonadotro A measurement of the Choriogonadotropin Beta in a Choriogonadotropin Beta pin Beta; biological specimen. Measurement Pregnancy Test

C64796 HCT Hematocrit The percentage of a whole blood specimen that is Hematocrit composed of red blood cells (erythrocytes).

C92543 HCVVLD HCV Viral Load A measurement of the hepatitis C viral load in a Hepatitis C Viral Load Measurement biological specimen.

C96664 HDAB Hepatitis D Virus A measurement of the hepatitis D virus antibody in a Hepatitis D Virus Antibody Antibody; biological specimen. Measurement Hepatitis Delta Antibody

C61041 HDL HDL Cholesterol A measurement of the high density lipoprotein Serum HDL Cholesterol cholesterol in a biological specimen. Measurement

C80187 HDL2 HDL-Cholestero A measurement of the high-density lipoprotein (HDL) HDL-Cholesterol Subclass 2 l Subclass 2 cholesterol subclass 2 in a biological specimen. Measurement

C80188 HDL3 HDL-Cholestero A measurement of the high-density lipoprotein (HDL) HDL-Cholesterol Subclass 3 l Subclass 3 cholesterol subclass 3 in a biological specimen. Measurement

C100425 HDLCLDLC HDL A relative measurement (ratio or percentage) of the HDL Cholesterol to LDL Cholesterol/LDL amount of HDL cholesterol compared to LDL Cholesterol Ratio Measurement Cholesterol cholesterol in a biological specimen. Ratio

C96665 HEIGMAB Hepatitis E Virus A measurement of the hepatitis E virus IgM antibody in Hepatitis E Virus IgM Antibody IgM Antibody a biological specimen. Measurement

C74709 HEINZ Heinz Bodies; A measurement of the Heinz bodies (small round Heinz-Ehrlich Body Measurement Heinz-Erhlich inclusions within the body of a red blood cell) in a Bodies biological specimen.

C74658 HELMETCE Helmet Cells A measurement of the Helmet cells (specialized Helmet Cell Count Keratocytes with two projections on either end that are tapered and hornlike) in a biological specimen.

C96668 HEXK Hexokinase A measurement of the hexokinase in a biological Hexokinase Measurement specimen.

C64848 HGB Hemoglobin A measurement of the hemoglobin in a biological Hemoglobin Measurement specimen.

C92258 HGBA Hemoglobin A A measurement of the hemoglobin A in a biological Hemoglobin A Measurement specimen.

C92259 HGBA2 Hemoglobin A2 A measurement of the hemoglobin A2 in a biological Hemoglobin A2 Measurement specimen.

C92260 HGBB Hemoglobin B A measurement of the hemoglobin B in a biological Hemoglobin B Measurement specimen.

C92261 HGBC Hemoglobin C A measurement of the hemoglobin C in a biological Hemoglobin C Measurement specimen.

C92262 HGBF Hemoglobin F; A measurement of the hemoglobin F in a biological Hemoglobin F Measurement Fetal specimen. Hemoglobin

C96689 HGBMET Methemoglobin A measurement of the methemoglobin in a biological Methemoglobin Measurement specimen.

C96616 HGBOXY Oxyhemoglobin A measurement of the oxyhemoglobin in a biological Oxyhemoglobin Measurement specimen.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 149 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C65047 - LBTESTCD - Laboratory Test Code Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C92272 HGRNA Hepatitis G RNA A measurement of the Hepatitis G RNA in a biological Hepatitis G RNA Measurement specimen.

C80189 HISTAMIN Histamine A measurement of the histamine in a biological Histamine Measurement specimen.

C74714 HIV12AB HIV-1/2 A measurement of the antibody reaction of a HIV-1 HIV-2 Antibody Measurement Antibody biological specimen to the either the HIV-1 or HIV-2 virus.

C74713 HIV1AB HIV-1 Antibody A measurement of the antibody reaction of a HIV-1 Antibody Measurement biological specimen to the HIV-1 virus.

C74715 HIV2AB HIV-2 Antibody A measurement of the antibody reaction of a HIV-2 Antibody Measurement biological specimen to the HIV-2 virus.

C92266 HIV2NUAC HIV-2 Nucleic A measurement of the HIV-2 nucleic acids in a HIV-2 Nucleic Acid Measurement Acid biological specimen.

C92265 HIVI24AG HIV-1 p24 A measurement of the HIV-1 p24 antigen in a HIV-1 p24 Antigen Measurement Antigen biological specimen.

C92263 HIVIMONA HIV-1 Group M A measurement of the HIV-1 group M and O nucleic HIV-1 Group M and O Nucleic Acid and O Nucleic acids in a biological specimen. Measurement Acid

C92264 HIVIOAB HIV-1 Group O A measurement of the HIV-1 group O antibody in a HIV-1 Group O Antibody Antibody biological specimen. Measurement

C92544 HIVVLD HIV Viral Load A measurement of the HIV viral load in a biological HIV Viral Load Measurement specimen.

C100460 HLAB27AG HLA-B27 A measurement of the human leukocyte antigen B27 HLA-B27 Antigen Measurement Antigen; Human (HLA-B27) in a biological specimen. Leukocyte Antigen B27

C96659 HMOSIDRN Hemosiderin A measurement of the hemosiderin complex in a - - - biological specimen.

C100447 HOMAIR Homostat Model An assessment of beta-cell function and insulin Homeostatic Model Assessment of Assess of Insulin resistance based on fasting blood glucose and insulin Insulin Resistance Rstn; concentrations. Homeostatic Model Assessment of Insulin Resistance

C74741 HOMOCY Homocysteine A measurement of the homocysteine amino acid in a Homocysteine Acid Measurement biological specimen.

C74704 HOWJOL Howell-Jolly A measurement of the Howell-Jolly bodies (spherical, Howell-Jolly Body Measurement Bodies blue-black condensed DNA inclusions within the body of a red blood cell that appear under Wright-stain) in a biological specimen.

C64802 HPOCROM Hypochromia An observation which indicates that the hemoglobin Hypochromia concentration in a red blood cell specimen has fallen below a specified level.

C74640 HRYCELY Hairy A relative measurement (ratio or percentage) of the Hairy Cell to Lymphocyte Ratio Cells/ hairy cells (b-cell lymphocytes with hairy projections Measurement Lymphocytes from the cytoplasm) to all lymphocytes in a biological specimen .

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 150 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C65047 - LBTESTCD - Laboratory Test Code Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C96698 HS12GGAB Herpes Simplex A measurement of the herpes simplex virus 1 and 2 Herpes Simplex Virus 1/2 IgG Virus 1/2 IgG IgG antibody in a biological specimen. Antibody Measurement Antibody; HSV-1/2 IgG Ab

C96666 HS12GMAB Herpes Simplex A measurement of the herpes simplex virus 1 and 2 Herpes Simplex Virus 1/2 IgM Virus 1/2 IgM IgM antibody in a biological specimen. Antibody Measurement Antibody; HSV-1/2 IgM Ab

C96697 HS1IGGAB Herpes Simplex A measurement of the herpes simplex virus 1 IgG Herpes Simplex Virus 1 IgG Virus 1 IgG antibody in a biological specimen. Antibody Measurement Antibody; HSV-1 IgG Antibody

C98738 HS1IGMAB Herpes Simplex A measurement of the Herpes Simplex virus 1 IgM Herpes Simplex Virus 1 IgM Virus 1 IgM antibodies in a biological specimen. Antibody Measurement Antibody

C96667 HS2IGGAB Herpes Simplex A measurement of the herpes simplex virus 2 IgG Herpes Simplex Virus 2 IgG Virus 2 IgG antibody in a biological specimen. Antibody Measurement Antibody; HSV-2 IgG Antibody

C98739 HS2IGMAB Herpes Simplex A measurement of the Herpes Simplex virus 2 IgM Herpes Simplex Virus 2 IgM Virus 2 IgM antibodies in a biological specimen. Antibody Measurement Antibody

C81984 HTPHAB Heterophile A measurement of the heterophile antibodies in a Heterophile Antibody Measurement Antibodies biological specimen.

C74863 HVA Homovanillic A measurement of the homovanillic acid metabolite in Homovanillic Acid Measurement Acid a biological specimen.

C74879 HYDCDN Hydrocodone A measurement of the hydrocodone present in a Hydrocodone Measurement biological specimen.

C74880 HYDMRPHN Hydromorphone A measurement of the hydromorphone present in a Hydromorphone Measurement biological specimen.

C96669 HYPERCHR Hyperchromia A measurement of the prevalence of the erthrocytes Hyperchromia Measurement with an elevated hemoglobin concentration.

C80190 HYPRLN Hydroxyproline A measurement of the total hydroxyproline in a Hydroxyproline Measurement biological specimen.

C74612 HYPSEGCE Hypersegmented A measurement of the hypersegmented (more than five Hypersegmented Neutrophil Cells lobes) neutrophils in a biological specimen. Measurement

C92273 IAH1N1VL Influenza A A measurement of the Influenza A H1N1 viral load in a Influenza A H1N1 Viral Load H1N1 Viral Load biological specimen. Measurement

C74718 IBCT Total Iron A measurement of the amount of iron needed to fully Total Iron Binding Capacity Binding Capacity saturate the transferrin in a biological specimen.

C74719 IBCU Unsaturated Iron A measurement of the binding capacity of unsaturated Unsaturated Iron Binding Capacity Binding Capacity iron in a biological specimen. Measurement

C81985 IC512AB Islet Cell 512 A measurement of the islet cell 512 antibody in a Islet Cell 512 Antibody Antibody biological specimen. Measurement

C81986 IC512AG Islet Cell 512 A measurement of the islet cell 512 antigen in a Islet Cell 512 Antigen Measurement Antigen biological specimen.

C81994 IFNA Interferon Alpha A measurement of the interferon alpha in a biological Interferon Alpha Measurement specimen.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 151 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C65047 - LBTESTCD - Laboratory Test Code Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C81995 IFNB Interferon Beta A measurement of the interferon beta in a biological Interferon Beta Measurement specimen.

C81996 IFNG Interferon A measurement of the interferon gamma in a Interferon Gamma Measurement Gamma biological specimen.

C81969 IGA Immunoglobulin A measurement of the Immunoglobulin A in a Immunoglobulin A Measurement A biological specimen.

C98745 IGD Immunoglobulin A measurement of the Immunoglobulin D in a Immunoglobulin D Measurement D biological specimen.

C81970 IGE Immunoglobulin A measurement of the Immunoglobulin E in a Immunoglobulin E Measurement E biological specimen.

C74864 IGF1 Insulin-like A measurement of the insulin-like growth factor-1 in a Insulin Like Growth Factor-1 Growth Factor-1 biological specimen. Measurement

C74865 IGF2 Insulin-like A measurement of the insulin-like growth factor-2 in a Insulin Like Growth Factor-2 Growth Factor-2 biological specimen. Measurement

C81971 IGG Immunoglobulin A measurement of the Immunoglobulin G in a Immunoglobulin G Measurement G biological specimen.

C81972 IGM Immunoglobulin A measurement of the Immunoglobulin M in a Immunoglobulin M Measurement M biological specimen.

C82044 INDICAN Indican A measurement of the indican present in a biological Indican Measurement specimen.

C92274 INFAVLD Influenza A Viral A measurement of the Influenza A viral load in a Influenza A Viral Load Measurement Load biological specimen.

C81987 INGAPAB Islet Neogenesis A measurement of the islet neogenesis associated Islet Neogenesis Associated Protein Assoc Protein protein antibody in a biological specimen. Antibody Measurement Antibody

C82020 INHIBINA Inhibin A A measurement of the inhibin A in a biological Inhibin A Measurement specimen.

C96681 INHIBINB Inhibin B A measurement of the inhibin B in a biological Inhibin B Measurement specimen.

C98748 INLCLR Inulin Clearance A measurement of the volume of serum or plasma that Inulin Clearance would be cleared of inulin by excretion of urine for a specified unit of time (e.g. one minute).

C64805 INR Prothrombin Intl. A ratio that represents the prothrombin time for a International Normalized Ratio of Normalized plasma specimen, divided by the result for a control Prothrombin Time Ratio plasma specimen, further standardized for the International Sensitivity Index of the tissue factor (thromboplastin) used in the test.

C74788 INSULIN Insulin A measurement of the insulin in a biological specimen. Insulin Measurement

C74805 INTLK1 Interleukin 1 A measurement of the interleukin 1 in a biological Interleukin 1 Measurement specimen.

C74806 INTLK10 Interleukin 10 A measurement of the interleukin 10 in a biological Interleukin 10 Measurement specimen.

C74807 INTLK11 Interleukin 11 A measurement of the interleukin 11 in a biological Interleukin 11 Measurement specimen.

C74808 INTLK12 Interleukin 12 A measurement of the interleukin 12 in a biological Interleukin 12 Measurement specimen.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 152 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C65047 - LBTESTCD - Laboratory Test Code Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C74809 INTLK13 Interleukin 13 A measurement of the interleukin 13 in a biological Interleukin 13 Measurement specimen.

C74810 INTLK14 Interleukin 14 A measurement of the interleukin 14 in a biological Interleukin 14 Measurement specimen.

C74811 INTLK15 Interleukin 15 A measurement of the interleukin 15 in a biological Interleukin 15 Measurement specimen.

C74812 INTLK16 Interleukin 16 A measurement of the interleukin 16 in a biological Interleukin 16 Measurement specimen.

C74813 INTLK17 Interleukin 17 A measurement of the interleukin 17 in a biological Interleukin 17 Measurement specimen.

C74814 INTLK18 Interleukin 18 A measurement of the interleukin 18 in a biological Interleukin 18 Measurement specimen.

C74815 INTLK19 Interleukin 19 A measurement of the interleukin 19 in a biological Interleukin 19 Measurement specimen.

C74816 INTLK2 Interleukin 2 A measurement of the interleukin 2 in a biological Interleukin 2 Measurement specimen.

C74817 INTLK20 Interleukin 20 A measurement of the interleukin 20 in a biological Interleukin 20 Measurement specimen.

C74818 INTLK21 Interleukin 21 A measurement of the interleukin 21 in a biological Interleukin 21 Measurement specimen.

C74819 INTLK22 Interleukin 22 A measurement of the interleukin 22 in a biological Interleukin 22 Measurement specimen.

C74820 INTLK23 Interleukin 23 A measurement of the interleukin 23 in a biological Interleukin 23 Measurement specimen.

C74821 INTLK24 Interleukin 24 A measurement of the interleukin 24 in a biological Interleukin 24 Measurement specimen.

C74822 INTLK25 Interleukin 25 A measurement of the interleukin 25 in a biological Interleukin 25 Measurement specimen.

C74823 INTLK26 Interleukin 26 A measurement of the interleukin 26 in a biological Interleukin 26 Measurement specimen.

C74824 INTLK27 Interleukin 27 A measurement of the interleukin 27 in a biological Interleukin 27 Measurement specimen.

C74825 INTLK28 Interleukin 28 A measurement of the interleukin 28 in a biological Interleukin 28 Measurement specimen.

C74826 INTLK29 Interleukin 29 A measurement of the interleukin 29 in a biological Interleukin 29 Measurement specimen.

C74827 INTLK3 Interleukin 3 A measurement of the interleukin 3 in a biological Interleukin 3 Measurement specimen.

C74828 INTLK30 Interleukin 30 A measurement of the interleukin 30 in a biological Interleukin 30 Measurement specimen.

C74829 INTLK31 Interleukin 31 A measurement of the interleukin 31 in a biological Interleukin 31 Measurement specimen.

C74830 INTLK32 Interleukin 32 A measurement of the interleukin 32 in a biological Interleukin 32 Measurement specimen.

C74831 INTLK33 Interleukin 33 A measurement of the interleukin 33 in a biological Interleukin 33 Measurement specimen.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 153 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C65047 - LBTESTCD - Laboratory Test Code Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C74832 INTLK4 Interleukin 4 A measurement of the interleukin 4 in a biological Interleukin 4 Measurement specimen.

C74833 INTLK5 Interleukin 5 A measurement of the interleukin 5 in a biological Interleukin 5 Measurement specimen.

C74834 INTLK6 Interleukin 6 A measurement of the interleukin 6 in a biological Interleukin 6 Measurement specimen.

C74835 INTLK7 Interleukin 7 A measurement of the interleukin 7 in a biological Interleukin 7 Measurement specimen.

C74836 INTLK8 Interleukin 8 A measurement of the interleukin 8 in a biological Interleukin 8 Measurement specimen.

C74837 INTLK9 Interleukin 9 A measurement of the interleukin 9 in a biological Interleukin 9 Measurement specimen.

C100439 IOHEXCLR Iohexol A measurement of the volume of serum or plasma that Iohexol Clearance Clearance would be cleared of Iohexol through excretion for a specified unit of time.

C98749 IOTCLR Iothalamate A measurement of the volume of serum or plasma that Iothalamate Clearance Clearance would be cleared of iothalamate by excretion of urine for a specified unit of time (e.g. one minute).

C98750 IOTCLRBS Iothalamate A measurement of the volume of serum or plasma that Iothalamate Clearance Adjusted for Clearance would be cleared of iothalamate by excretion of urine BSA Adjusted for for a specified unit of time (e.g. one minute), adjusted BSA for body size.

C74679 IRON Iron; FE A measurement of the iron in a biological specimen. Iron Measurement

C80180 ISOPRF2 F2-Isoprostane A measurement of the F2-isoprostane in a biological F2 Isoprostane Measurement specimen.

C100459 JO1AB Jo-1 Antibody A measurement of the Jo-1 antibody in a biological Jo-1 Antibody Measurement specimen.

C64853 K Potassium A measurement of the potassium in a biological Potassium Measurement specimen.

C79462 KCREAT Potassium/ A relative measurement (ratio or percentage) of the Potassium to Creatinine Ratio Creatinine potassium to creatinine in a biological specimen. Measurement

C64854 KETONES Ketones A measurement of the ketones in a biological Ketone Measurement specimen.

C100433 KIM1 Kidney Injury A measurement of the kidney injury molecule-1 Kidney Injury Molecule-1 Molecule-1; (Kim-1) in a biological specimen. Measurement KIM-1; Hepatitis A Virus Cellular Receptor 1

C98730 KLCFR Kappa Light A measurement of the free kappa light chain in a Free Kappa Light Chain Chain, Free biological specimen. Measurement

C98731 KLCLLCFR Kappa Lt A relative measurement (ratio or percentage) of the Free Kappa Light Chain to Free Chain,Free/ free kappa light chain to the free lambda light chain in Lambda Light Chain Ratio Lambda Lt a biological specimen. Measurement Chain,Free

C96688 KRCYMG Megakaryocytes A measurement of the megakaryocytes per unit of a Megakaryocyte Count biological specimen.

C98867 KRCYMGCE Megakaryocytes/ A relative measurement (ratio or percentage) of the Megakaryocyte to Total CellRatio Total Cells megakaryocytes to total cells in a biological specimen Measurement (for example a bone marrow specimen).

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 154 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C65047 - LBTESTCD - Laboratory Test Code Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C96682 KURLOFCE Kurloff Cells A measurement of the large secretory Kurloff Cells Measurement granule-containing immune cells in a biological specimen taken from members of certain genera of the Caviidae family.

C79450 LACTICAC Lactic Acid; A measurement of the lactic acid in a biological Lactic Acid Measurement 2-hydroxypropan specimen. oic acid; Lactate

C64855 LDH Lactate A measurement of the lactate dehydrogenase in a Lactate Dehydrogenase Dehydrogenase biological specimen. Measurement

C74887 LDH1 LDH Isoenzyme A measurement of the lactate dehydrogenase Lactate Dehydrogenase Isoenzyme 1 1 isoenzyme 1 in a biological specimen. Measurement

C79451 LDH1LDH LDH Isoenzyme A relative measurement (ratio or percentage) of the LDH Isoenzyme 1 to LDH Ratio 1/LDH lactate dehydrogenase isoenzyme 1 to total lactate Measurement dehydrogenase in a biological specimen.

C74888 LDH2 LDH Isoenzyme A measurement of the lactate dehydrogenase Lactate Dehydrogenase Isoenzyme 2 2 isoenzyme 2 in a biological specimen. Measurement

C79452 LDH2LDH LDH Isoenzyme A relative measurement (ratio or percentage) of the LDH Isoenzyme 2 to LDH Ratio 2/LDH lactate dehydrogenase isoenzyme 2 to total lactate Measurement dehydrogenase in a biological specimen.

C74889 LDH3 LDH Isoenzyme A measurement of the lactate dehydrogenase Lactate Dehydrogenase Isoenzyme 3 3 isoenzyme 3 in a biological specimen. Measurement

C79453 LDH3LDH LDH Isoenzyme A relative measurement (ratio or percentage) of the LDH Isoenzyme 3 to LDH Ratio 3/LDH lactate dehydrogenase isoenzyme 3 to total lactate Measurement dehydrogenase in a biological specimen.

C74890 LDH4 LDH Isoenzyme A measurement of the lactate dehydrogenase Lactate Dehydrogenase Isoenzyme 4 4 isoenzyme 4 in a biological specimen. Measurement

C79454 LDH4LDH LDH Isoenzyme A relative measurement (ratio or percentage) of the LDH Isoenzyme 4 to LDH Ratio 4/LDH lactate dehydrogenase isoenzyme 4 to total lactate Measurement dehydrogenase in a biological specimen.

C74891 LDH5 LDH Isoenzyme A measurement of the lactate dehydrogenase Lactate Dehydrogenase Isoenzyme 5 5 isoenzyme 5 in a biological specimen. Measurement

C79455 LDH5LDH LDH Isoenzyme A relative measurement (ratio or percentage) of the LDH Isoenzyme 5 to LDH Ratio 5/LDH lactate dehydrogenase isoenzyme 5 to total lactate Measurement dehydrogenase in a biological specimen.

C79449 LDHCREAT Lactate A relative measurement (ratio or percentage) of the Lactate Dehydrogenase to Creatinine Dehydrogenase/ lactate dehydrogenase to creatinine in a biological Ratio Measurement Creatinine specimen.

C61042 LDL LDL Cholesterol A measurement of the low density lipoprotein Serum LDL Cholesterol cholesterol in a biological specimen. Measurement

C74866 LEPTIN Leptin A measurement of the leptin hormone in a biological Leptin Measurement specimen.

C64856 LEUKASE Leukocyte A measurement of the enzyme which indicates the Leukocyte Esterase Measurement Esterase presence of white blood cells in a biological specimen.

C79467 LGLUCLE Large Unstained A relative measure (ratio or percentage) of the large Large Unstained Cells to Leukocytes Cells/ unstained cells to leukocytes in a biological specimen. Ratio Measurement Leukocytes

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 155 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C65047 - LBTESTCD - Laboratory Test Code Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C74659 LGUNSCE Large Unstained A measurement of the large, peroxidase-negative cells Large Unstained Cell Count Cells which cannot be further characterized (i.e. as large lymphocytes, virocytes, or stem cells) present in a biological specimen.

C74790 LH Luteinizing A measurement of the luteinizing hormone in a Luteinizing Hormone Measurement Hormone biological specimen.

C64807 LIPASE Triacylglycerol A measurement of the pancreatic lipase in a biological Triacylglycerol Lipase Measurement Lipase specimen.

C96683 LKM1AB Liver Kidney A measurement of the liver kidney microsomal type 1 Liver Kidney Microsomal Type 1 Microsomal antibody in a biological specimen. Antibody Measurement Type 1 Antibody; LKM-1

C100456 LKM1IAAB Liver Kidney A measurement of the liver kidney microsomal type 1 Liver Kidney Microsomal Type 1 Microsomal IgA antibodies in a biological specimen. IgA Antibody Measurement Type 1 IgA Ab

C100454 LKM1IGAB Liver Kidney A measurement of the liver kidney microsomal type 1 Liver Kidney Microsomal Type 1 Microsomal IgG antibodies in a biological specimen. IgG Antibody Measurement Type 1 IgG Ab

C100455 LKM1IMAB Liver Kidney A measurement of the liver kidney microsomal type 1 Liver Kidney Microsomal Type 1 Microsomal IgM antibodies in a biological specimen. IgM Antibody Measurement Type 1 IgM Ab

C98732 LLCFR Lambda Light A measurement of the free lambda light chain in a Free Lambda Light Chain Chain, Free biological specimen. Measurement

C82022 LPA Lipoprotein-a A measurement of the lipoprotein-a in a biological Lipoprotein a Measurement specimen.

C92275 LPNAG Legionella A measurement of the Legionella pneumophila antigen Legionella pneumophila Antigen pneumophila in a biological specimen. Measurement Antigen

C92277 LPNGMAB Legionella A measurement of the Legionella pneumophila IgG and Legionella pneumophila IgG IgM pneumophila IgG IgM in a biological specimen. Antibody Measurement IgM Antibody

C92276 LPNIGGAB Legionella A measurement of the Legionella pneumophila IgG Legionella pneumophila IgG pneumophila IgG antibody in a biological specimen. Antibody Measurement Antibody

C92278 LPNIGMAB Legionella A measurement of the Legionella pneumophila IgM Legionella pneumophila IgM pneumophila IgM antibody in a biological specimen. Antibody Measurement Antibody

C82021 LTF Lactoferrin; A measurement of the lactoferrin in a biological Lactoferrin Measurement Lactotransferrin specimen.

C51949 LYM Lymphocytes A measurement of the lymphocytes in a biological Lymphocyte Count specimen.

C64818 LYMAT Lymphocytes A measurement of the atypical lymphocytes in a Atypical Lymphocyte Count Atypical biological specimen.

C64819 LYMATLE Lymphocytes A relative measurement (ratio or percentage) of the Atypical Lymphocyte To Leukocyte Atypical/ atypical lymphocytes to leukocytes in a biological Ratio Leukocytes specimen.

C98751 LYMCE Lymphocytes/ A relative measurement (ratio or percentage) of the Lymphocyte to Total Cell Ratio Total Cells lymphocytes to total cells in a biological specimen Measurement (for example a bone marrow specimen).

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 156 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C65047 - LBTESTCD - Laboratory Test Code Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C100444 LYMIM Immature A measurement of the immature lymphocytes in a Immature Lymphocytes Lymphocytes biological specimen. Measurement

C100443 LYMIMLE Immature A relative measurement (ratio or percentage) of the Immature Lymphocytes to Lymphocytes/ immature lymphocytes to leukocytes in a biological Leukocytes Ratio Measurement Leukocytes specimen.

C64820 LYMLE Lymphocytes/ A relative measurement (ratio or percentage) of the Lymphocyte To Leukocyte Ratio Leukocytes lymphocytes to leukocytes in a biological specimen.

C74613 LYMMCE Lymphoma Cells A measurement of the malignant lymphocytes in a Lymphoma Cell Count biological specimen.

C74910 LYMMCELY Lymphoma A relative measurement (ratio or percentage) of the Lymphoma Cell to Lymphocyte Cells/ malignant lymphocytes to all lymphocytes in a Ratio Measurement Lymphocytes biological specimen.

C81955 LYMPHOTC Lymphotactin; A measurement of the lymphotactin in a biological Lymphotactin Measurement Chemokine specimen. Ligand 1

C74618 LYMPL Plasmacytoid A measurement of the plasmacytoid lymphocytes Plasmacytoid Lymphocyte Count Lymphocytes; (lymphocytes with peripherally clumped chromatin and Plymphocytes often deep blue cytoplasm, and that appear similar to plasma cells) in a biological specimen.

C74648 LYMPLLY Plasmacytoid A relative measurement (ratio or percentage) of the Plasmacytoid Lymphocyte to Lymphocytes/ plasmacytoid lymphocytes (lymphocytes with Lymphocyte Ratio Measurement Lymphocytes peripherally clumped chromatin and often deep blue cytoplasm, and that appear similar to plasma cells) to all lymphocytes in a biological specimen.

C74629 LYMRCT Reactive A measurement of the reactive lymphocytes Reactive Lymphocyte Count Lymphocytes (lymphocytes which have become large due to an Measurement antigen reaction) in a biological specimen.

C74654 LYMRCTLY Reactive A relative measurement (ratio or percentage) of the Reactive Lymphocyte to Lymphocytes/ reactive lymphocytes (lymphocytes which have Lymphocyte Ratio Measurement Lymphocytes become large due to an antigen reaction) to all lymphocytes in a biological specimen.

C64821 MACROCY Macrocytes A measurement of the macrocytes in a biological Macrocyte Count specimen.

C74614 MAYHEG May-Hegglin A measurement of the May-Hegglin anomaly in a May-Hegglin Anomaly Measurement Anomaly blood sample. This anomaly is characterized by large, misshapen platelets and the presence of Dohle bodies in leukocytes.

C64797 MCH Ery. Mean A quantitative measurement of the mean amount of Erythrocyte Mean Corpuscular Corpuscular hemoglobin per erythrocyte in a biological specimen. Hemoglobin Hemoglobin

C64798 MCHC Ery. Mean A quantitative measurement of the mean amount of Erythrocyte Mean Corpuscular Corpuscular hemoglobin per erythrocytes in a specified volume of Hemoglobin Concentration HGB a biological specimen. Concentration

C82025 MCP1 Monocyte A measurement of the monocyte chemotactic protein Monocyte Chemotactic Protein 1 Chemotactic 1 in a biological specimen. Measurement Protein 1

C92291 MCPROT Monoclonal A measurement of homogenous immunoglobulin Monoclonal Protein Measurement Immunoglobulin resulting from the proliferation of a single clone of Protein; plasma cells in a biological specimen. Paraprotein

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 157 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C65047 - LBTESTCD - Laboratory Test Code Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C80191 MCSF Macrophage A measurement of the macrophage colony stimulating Macrophage Colony Stimulating Colony factor in a biological specimen. Factor Measurement Stimulating Factor

C64799 MCV Ery. Mean A quantitative measurement of the mean volume of Erythrocyte Mean Corpuscular Corpuscular erythrocytes in a biological specimen. Volume Volume

C81956 MDC Macrophage-Der A measurement of the macrophage-derived chemokine Macrophage-Derived Chemokine ived Chemokine; in a biological specimen. Measurement Chemokine Ligand 22

C74615 METAMY Metamyelocytes A measurement of the metamyelocytes (small, Metamyelocyte Count myelocytic neutrophils with an indented nucleus) in a biological specimen.

C98754 METAMYCE Metamyelocytes/ A relative measurement (ratio or percentage ) of the Metamyelocyte to Total Cell Ratio Total Cells metamyelocytes (small, myelocytic neutrophils with Measurement an indented nucleus) to total cells in a biological specimen (for example a bone marrow specimen).

C74645 METAMYLE Metamyelocytes/ A relative measurement (ratio or percentage) of the Metamyelocyte to Leukocyte Ratio Leukocytes metamyelocytes (small, myelocytic neutrophils with Measurement an indented nucleus) to all leukocytes in a biological specimen.

C74881 METHDN Methadone A measurement of the methadone present in a Methadone Measurement biological specimen.

C74882 METHQLDN Methaqualone A measurement of the methaqualone present in a Methaqualone Measurement biological specimen.

C64840 MG Magnesium A measurement of the magnesium in a biological Magnesium Measurement specimen.

C79436 MGB Myoglobin A measurement of myoglobin in a biological Myoglobin Measurement specimen.

C79456 MGCREAT Magnesium/ A relative measurement (ratio or percentage) of the Magnesium to Creatinine Ratio Creatinine magnesium to creatinine in a biological specimen. Measurement

C64822 MICROCY Microcytes A measurement of the microcytes in a biological Microcyte Count specimen.

C82023 MIP1A Macrophage A measurement of the macrophage inflammatory Macrophage Inflammatory Protein 1 Inflammatory protein 1 alpha in a biological specimen. Alpha Measurement Protein 1 Alpha; Chemokine Ligand 3

C82024 MIP1B Macrophage A measurement of the macrophage inflammatory Macrophage Inflammatory Protein 1 Inflammatory protein 1 beta in a biological specimen. Beta Measurement Protein 1 Beta; Chemokine Ligand 4

C74867 MLATONIN Melatonin A measurement of the melatonin hormone in a Melatonin Measurement biological specimen.

C74660 MLIGCE Malignant Cells, A measurement of the malignant cells of all types in a Malignant Cell Count NOS biological specimen.

C74643 MLIGCEBC Malignant Cells, A relative measurement (ratio or percentage) of the Malignant Cell to Blood Cell Ratio NOS/Blood malignant cells of all types to all blood cells in a Measurement Cells biological specimen.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 158 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C65047 - LBTESTCD - Laboratory Test Code Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C96690 MMA Methylmalonic A measurement of the methylmalonic acid in a Methylmalonic Acid Measurement Acid biological specimen.

C80192 MMP1 Matrix A measurement of the matrix metalloproteinase 1 in a Matrix Metalloproteinase 1 Metalloproteinas biological specimen. Measurement e 1; Interstitial Collagenase

C80193 MMP2 Matrix A measurement of the matrix metalloproteinase 2 in a Matrix Metalloproteinase 2 Metalloproteinas biological specimen. Measurement e 2; Gelatinase A

C80194 MMP3 Matrix A measurement of the matrix metalloproteinase 3 in a Matrix Metalloproteinase 3 Metalloproteinas biological specimen. Measurement e 3; Stromelysin 1

C80195 MMP7 Matrix A measurement of the matrix metalloproteinase 7 in a Matrix Metalloproteinase 7 Metalloproteinas biological specimen. Measurement e 7; Matrilysin

C80196 MMP8 Matrix A measurement of the matrix metalloproteinase 8 in a Matrix Metalloproteinase 8 Metalloproteinas biological specimen. Measurement e 8; Neutrophil Collagenase

C80197 MMP9 Matrix A measurement of the matrix metalloproteinase 9 in a Matrix Metalloproteinase 9 Metalloproteinas biological specimen. Measurement e 9; Gelatinase B

C64823 MONO Monocytes A measurement of the monocytes in a biological Monocyte Count specimen.

C74631 MONOBL Monoblasts A measurement of the monoblast cells in a biological Monoblast Count specimen.

C74646 MONOBLLE Monoblasts/ A relative measurement (ratio or percentage) of the Monoblast to Leukocyte Ratio Leukocytes monoblasts to leukocytes in a biological specimen. Measurement

C98872 MONOCE Monocytes/Total A relative measurement (ratio or percentage) of the Monocytes to Total Cells monocytes to total cells in a biological specimen (for CellRatioMeasurement example a bone marrow specimen).

C96676 MONOIM Immature A measurement of the immature monocytes in a Immature Monocyte Count Monocytes biological specimen.

C96677 MONOIMLE Immature A relative measurement (ratio or percentage) of Immature Monocyte to Leukocyte Monocytes/ immature monocytes to total leukocytes in a Ratio Measurement Leukocytes biological specimen.

C64824 MONOLE Monocytes/ A relative measurement (ratio or percentage) of the Monocyte To Leukocyte Ratio Leukocytes monocytes to leukocytes in a biological specimen.

C74883 MORPHINE Morphine A measurement of the morphine present in a biological Morphine Measurement specimen.

C96686 MPC Mean Platelet A measurement of the mean platelet component Mean Platelet Component Component (platelet activity) in a blood specimen. Measurement

C80198 MPO Myeloperoxidase A measurement of the myeloperoxidase in a biological Myeloperoxidase Measurement specimen.

C92280 MPOAB Myeloperoxidase A measurement of the myeloperoxidase antibody in a Myeloperoxidase Antibody Antibody biological specimen. Measurement

C74730 MPV Mean Platelet A measurement of the average size of the platelets Mean Platelet Volume Measurement Volume present in a blood sample.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 159 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C65047 - LBTESTCD - Laboratory Test Code Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C74721 MUCTHR Mucous Threads A measurement of the mucous threads present in a Mucous Thread Measurement biological specimen.

C74632 MYBLA Myeloblasts A measurement of the myeloblast cells in a biological Myeloblast Count specimen.

C64825 MYBLALE Myeloblasts/ A relative measure (ratio or percentage) of the Myeloblast To Leukocyte Ratio Leukocytes myeloblasts to leukocytes in a biological specimen.

C92283 MYBLAT1 Type I A measurement of type I myeloblast cells per unit of a Type I Myeloblasts Measurement Myeloblasts biological specimen.

C92284 MYBLAT2 Type II A measurement of type II myeloblast cells per unit of a Type II Myeloblasts Measurement Myeloblasts biological specimen.

C92285 MYBLAT3 Type III A measurement of type III myeloblast cells per unit of Type III Myeloblasts Measurement Myeloblasts a biological specimen.

C74662 MYCY Myelocytes A measurement of the myelocytes in a biological Myelocyte Count specimen.

C98868 MYCYCE Myelocytes/ A relative measurement (ratio or percentage) of the Myelocyte to Total CellRatio Total Cells myelocytes to total cells in a biological specimen (for Measurement example a bone marrow specimen).

C64826 MYCYLE Myelocytes/ A relative measurement (ratio or percentage) of the Myelocyte To Leukocyte Ratio Leukocytes myelocytes to leukocytes in a biological specimen.

C92242 MYPCERPC Myeloid/ A relative measurement (ratio or percentage) of Myeloid to Erythroid Ratio Erythroid Ratio myeloid progenitor cells to erythrocyte precursor Measurement cells in a biological specimen.

C92241 MYTBGIR Mycobacterium A measurement of the amount of interferon gamma Mycobacterium tuberculosis tuberculosis IFN that is released when Mycobacterium tuberculosis Interferon Gamma Response Gamma antigen is incubated with a biological specimen, Response usually blood. Increased amounts of interferon gamma suggests a prior or existing M. tuberculosis infection.

C92279 MYTBNUAC Mycobacterium A measurement of the Mycobacterium tuberculosis Mycobacterium tuberculosis Nucleic tuberculosis nucleic acid in a biological specimen. Acid Measurement Nucleic Acid

C79464 NACREAT Sodium/ A relative measurement (ratio or percentage) of the Sodium to Creatinine Ratio Creatinine sodium to creatinine in a biological specimen. Measurement

C79459 NAG N-Acetyl A measurement of N-acetyl glucosamide in a N-Acetyl Glucosamide Measurement Glucosamide; biological specimen. N-Acetyl Glucosamine

C79460 NAGCREAT N-Acetyl A relative measurement (ratio or percentage) of the N-Acetyl Glucosamide to Creatinine Glucosamide/ N-acetyl glucosamide to creatinine in a biological Ratio Measurement Creatinine specimen.

C79437 NCTD5P 5 Prime A measurement of the 5'-nucleotidase in a biological 5 Prime Nucleotidase Measurement Nucleotidase; specimen. 5'-Ribonucleotid e Phosphohydrolas e

C80199 NEOPTERN Neopterin A measurement of the neopterin in a biological Neopterin Measurement specimen.

C63321 NEUT Neutrophils A measurement of the neutrophils in a biological Absolute Neutrophil Count specimen.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 160 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C65047 - LBTESTCD - Laboratory Test Code Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C64830 NEUTB Neutrophils Band A measurement of the banded neutrophils in a Neutrophil Band Form Count Form biological specimen.

C64831 NEUTBLE Neutrophils Band A relative measurement (ratio or percentage) of the Neutrophil Band Form To Leukocyte Form/ banded neutrophils to leukocytes in a biological Ratio Leukocytes specimen.

C98763 NEUTCE Neutrophils/ A relative measurement (ratio or percentage) of the Neutrophil to Total Cell Ratio Total Cells neutrophils to total cells in a biological specimen (for Measurement example a bone marrow specimen).

C96651 NEUTGT Giant A measurement of the giant neutrophils in a biological Giant Neutrophil Count Neutrophils specimen.

C96678 NEUTIM Immature A measurement of the total immature neutrophils in a Immature Neutrophil Count Neutrophils biological specimen.

C100442 NEUTIMLE Immature A relative measurement (ratio or percentage) of the Immature Neutrophils to Leukocytes Neutrophils/ immature neutrophils to leukocytes in a biological Ratio Measurement Leukocytes specimen.

C64827 NEUTLE Neutrophils/ A relative measurement (ratio or percentage) of the Neutrophil To Leukocyte Ratio Leukocytes neutrophils to leukocytes in a biological specimen.

C84822 NEUTMM Neutrophilic A measurement of the neutrophilic metamyelocytes in Neutrophilic Metamyelocyte Count Metamyelocytes a biological specimen.

C84823 NEUTMY Neutrophilic A measurement of the neutrophilic myelocytes in a Neutrophilic Myelocyte Count Myelocytes biological specimen.

C81997 NEUTSG Neutrophils, A measurement of the segmented neutrophils in a Segmented Neutrophil Count Segmented biological specimen.

C82045 NEUTSGLE Neutrophils, A relative measurement (ratio or percentage) of Segmented Neutrophil to Leukocyte Segmented/ segmented neutrophils to leukocytes in a biological Ratio Measurement Leukocytes specimen.

C74628 NEUTVAC Vacuolated A measurement of the neutrophils containing small Vacuolated Neutrophil Count Neutrophils vacuoles in a biological specimen.

C92298 NGON Neisseria Examination of a biological specimen to detect the Neisseria gonorrhoeae Screening gonorrhoeae presence of Neisseria gonorrhoeae. Screening

C64810 NITRITE Nitrite A measurement of the nitrite in a urine specimen. Nitrite Measurement

C98762 NKCE Natural Killer A measurement of the total natural killer cells in a Natural Killer Cell Count Cells biological specimen.

C74868 NOREPIN Noradrenaline; A measurement of the norepinephrine hormone in a Noradrenaline Measurement Norepinephrine biological specimen.

C100434 NPAP Non-Prostatic A measurement of the non-prostatic acid phosphatase Non-Prostatic Acid Phosphatase Acid in a biological specimen. Measurement Phosphatase

C74892 NPY Neuropeptide Y A measurement of the neuropeptide Y in a biological Neuropeptide Y Measurement specimen.

C74743 NTELOP N-telopeptide A measurement of the N-telopeptide in a biological N-telopeptide Measurement specimen.

C82039 NTXI Type I Collagen A measurement of the type I collagen N-telopeptides Type I Collagen N-Telopeptide N-Telopeptides in a biological specimen. Measurement

C82041 NTXII Type II Collagen A measurement of the type II collagen N-telopeptides Type II Collagen N-Telopeptide N-Telopeptides in a biological specimen. Measurement

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 161 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C65047 - LBTESTCD - Laboratory Test Code Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C74686 OCCBLD Occult Blood A measurement of the blood in body products such as a Occult Blood Measurement stool sample, not detectable on gross examination.

C74796 OPIATE Opiate A measurement of any opiate class drug present in a Opiate Measurement biological specimen.

C74801 OSMLTY Osmolality A measurement of the osmoles of solute per unit of Osmolality Measurement biological specimen.

C74802 OSMRTY Osmolarity A measurement of the osmoles of solute per liter of Osmolarity Measurement solution.

C74744 OSTEOC Osteocalcin A measurement of the osteocalcin in a biological Osteocalcin Measurement specimen.

C100452 OVAPARS Ova and Parasite A measurement of the parasites and ova in a biological Ova and Parasite Measurement specimen.

C92250 OXALATE Oxalate; A measurement of the oxalate in a biological Oxalate Measurement Ethanedioate specimen.

C96614 OXYCAP Oxygen Capacity A measurement of the maximum amount of oxygen Oxygen Capacity Measurement that can be combined chemically with hemoglobin in a volume of blood.

C74884 OXYCDN Oxycodone; A measurement of the oxycodone present in a Oxycodone Measurement Oxycontin biological specimen.

C68032 OXYSAT Oxygen A measurement of the oxygen-hemoglobin saturation Oxygen Saturation Measurement Saturation of a volume of blood.

C74869 OXYTOCIN Oxytocin; A measurement of the oxytocin hormone in a Oxytocin Measurement Oxytoxin biological specimen.

C96625 P1NP Procollagen 1 A measurement of the procollagen 1 N-terminal Procollagen 1 N-Terminal N-Terminal propeptide in a biological specimen. Propeptide Measurement Propeptide; Amino-terminal propeptide of type 1 procollagen; P1NP Aminoterm Type 1

C82030 PAI1 Plasminogen A measurement of the plasminogen activator Plasminogen Activator Inhibitor-1 Activator inhibitor-1 in a biological specimen. Measurement Inhibitor-1

C81989 PAI1AG Plasminogen A measurement of the plasminogen activator Plasminogen Activator Inhibitor-1 Activator inhibitor-1 antigen in a biological specimen. Antigen Measurement Inhibitor-1 AG

C80204 PAP Prostatic Acid A measurement of the prostatic acid phosphatase in a Prostatic Acid Phosphatase Phosphatase biological specimen. Measurement

C82031 PAPPA Pregnancy-Assoc A measurement of the pregnancy-associated plasma Pregnancy-Associated Plasma iated Plasma protein-A in a biological specimen. Protein-A Measurement Protein-A

C74616 PAPPEN Pappenheimer A measurement of the cells containing Pappenheimer Pappenheimer Body Count Bodies Bodies (violet or blue staining ferritin granules usually found along the periphery of the red blood cells) in a biological specimen.

C96617 PB19GGAB Parvovirus B19 A measurement of the Parvovirus B19 IgG antibody in Parvovirus B19 IgG Antibody IgG Antibody a biological specimen. Measurement

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 162 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C65047 - LBTESTCD - Laboratory Test Code Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C96618 PB19GMAB Parvovirus B19 A measurement of the Parvovirus B19 IgM antibody in Parvovirus B19 IgM Antibody IgM Antibody a biological specimen. Measurement

C82625 PCO2 Partial Pressure A measurement of the pressure of carbon dioxide in a Partial Pressure of Carbon Dioxide Carbon Dioxide biological specimen. Measurement

C74694 PCP Phencyclidine; A measurement of the phencyclidine present in a Phencyclidine Measurement Phenylcyclohexy biological specimen. lpiperidine

C81962 PDW Platelet A measurement of the range of platelet sizes in a Platelet Distribution Width Distribution biological specimen. Width

C74617 PELGERH Pelger Huet A measurement of the Pelger Huet Anomaly (nuclei of Pelger Huet Anomaly Measurement Anomaly neutrophils and eosinophils appear rod-like, spherical or dumbbell shaped) in a biological specimen.

C81988 PEMAB Pemphigoid A measurement of the pemphigoid antibodies in a Pemphigoid Antibody Measurement Antibodies biological specimen.

C100122 PEPSNG Pepsinogen A measurement of the pepsinogen in a biological Pepsinogen Measurement specimen.

C100469 PEPSNGA Pepsinogen A; A measurement of the pepsinogen A in a biological Pepsinogen A Measurement PGA specimen.

C100470 PEPSNGC Pepsinogen C; A measurement of the pepsinogen C in a biological Pepsinogen C Measurement PGC specimen.

C100467 PEPSNGI Pepsinogen I; A measurement of the pepsinogen I in a biological Pepsinogen I Measurement PGI specimen.

C100468 PEPSNGII Pepsinogen II; A measurement of the pepsinogen II in a biological Pepsinogen II Measurement PGII specimen.

C100446 PERTHRBL Proerythroblast A measurement of the proerythroblasts in a biological Proerythroblast Measurement specimen.

C45997 PH pH A measure of the acidity or alkalinity of a fluid on a pH scale of 0 to 14.

C74695 PHENTHZ Phenothiazine; A measurement of the phenothiazine present in a Phenothiazine Measurement Dibenzothiazine biological specimen.

C64857 PHOS Phosphate; A measurement of the phosphate in a biological Phosphate Measurement Phosphorus; specimen. Inorganic Phosphate

C79461 PHOSCRT Phosphate/ A relative measurement (ratio or percentage) of the Phosphate to Creatinine Ratio Creatinine phosphate to creatinine in a biological specimen. Measurement

C96623 PHOSLPD Phospholipid A measurement of the phospholipids in a biological Phospholipid Measurement specimen.

C82033 PICP Procollagen A measurement of the procollagen-1 carboxy-terminal Procollagen Type I Carboxy Type I Carboxy peptide in a biological specimen. Terminal Peptide Measurement Term Peptide

C51951 PLAT Platelets A measurement of the platelets in a biological Platelet Count specimen.

C96624 PLATCLMP Platelet Clumps; A measurement of the platelet clumps in a biological Platelet Clumps Count PLT Clumps specimen.

C74728 PLATGNT Giant Platelets A measurement of the giant (larger than 7um in Giant Platelet Count diameter) platelets in a biological specimen.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 163 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C65047 - LBTESTCD - Laboratory Test Code Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C100424 PLATHCT Platelet A relative measurement (ratio or percentage) of the Platelet Hematocrit Measurement Hematocrit; proportion of the volume of blood taken up by Thrombocytocrit platelets.

C74729 PLATLRG Large Platelets A measurement of the large (between 4 um and 7um in Large Platelet Count diameter) platelets in a biological specimen.

C96679 PLSIMCE Immature Plasma A measurement of the immature plasma cells in a Immature Plasma Cell Count Cells biological specimen.

C96680 PLSIMCLY Immature Plasma A relative measurement (ratio or percentage) of Immature Plasma Cell to Cells/ immature plasma cells to total lymphocytes in a Lymphocyte Ratio Measurement Lymphocytes biological specimen.

C74661 PLSMCE Mature Plasma A measurement of the mature plasma cells Mature Plasma Cell Count Cells; (plasmacytes) in a biological specimen. Plasmacytes

C98869 PLSMCECE Plasma A relative measurement (ratio or percentage) of the Plasma Cell to Total CellRatio Cells/Total Cells mature plasma cells (plasmacytes) to total cells in a Measurement biological specimen (for example a bone marrow specimen).

C74911 PLSMCELY Mature Plasma A relative measurement (ratio or percentage) of the Mature Plasma Cell to Lymphocyte Cells/ mature plasma cells (plasmacytes) to all lymphocytes Ratio Measurement Lymphocytes in a biological specimen.

C100453 PLSMDM Plasmodium Examination of a biological specimen to detect the Plasmodium Measurement presence of any protozoan belonging to the Plasmodium genus.

C74619 PLSPCE Precursor A measurement of the precursor (blast stage) plasma Precursor Plasma Cell Count Plasma Cells; cells (antibody secreting cells derived from B cells via Plasmablast antigen stimulation) in a biological specimen.

C74650 PLSPCELY Precursor A relative measurement (ratio or percentage) of the Precursor Plasma Cell to Plasma precursor (blast stage) plasma cells (antibody Lymphocyte Ratio Measurement Cells/ secreting cells derived from B cells via antigen Lymphocytes stimulation) to all lymphocytes in a biological specimen.

C80201 PNCTPP Pancreatic A measurement of the pancreatic polypeptide in a Pancreatic Polypeptide Polypeptide biological specimen. Measurement

C71251 PO2 Partial Pressure A measurement of the pressure of oxygen in a Partial Pressure of Oxygen Oxygen biological specimen. Measurement

C79602 POIKILO Poikilocytes A measurement of the odd-shaped erythrocytes in a Poikilocyte Measurement whole blood specimen.

C74649 POIKRBC Poikilocytes/ A relative measurement (ratio or percentage) of the Poikilocyte to Erythrocyte Ratio Erythrocytes poikilocytes, or irregularly shaped erythrocytes, to all Measurement erythrocytes in a biological specimen.

C64803 POLYCHR Polychromasia A measurement of the blue-staining characteristic of Polychromasia newly generated erythrocytes.

C100435 PREALB Prealbumin A measurement of the prealbumin in a biological Prealbumin Measurement specimen.

C64829 PRLYMLE Prolymphocytes/ A relative measurement (ratio or percentage) of Prolymphocyte To Leukocyte Ratio Leukocytes prolymphocytes to leukocytes in a biological specimen.

C74791 PROGEST Progesterone A measurement of the progesterone hormone in a Progesterone Measurement biological specimen.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 164 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C65047 - LBTESTCD - Laboratory Test Code Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C81967 PROINSUL Proinsulin A measurement of the proinsulin in a biological Proinsulin Measurement specimen.

C74870 PROLCTN Prolactin A measurement of the prolactin hormone in a Prolactin Measurement biological specimen.

C74620 PROLYM Prolymphocytes A measurement of the prolymphocytes in a biological Prolymphocyte Count specimen.

C74651 PROLYMLY Prolymphocytes/ A relative measurement (ratio or percentage) of the Prolymphocyte to Lymphocyte Ratio Lymphocytes prolymphocytes to all lymphocytes in a biological Measurement specimen.

C74652 PROMONLE Promonocytes/ A relative measurement (ratio or percentage) of the Promonocyte to Lymphocyte Ratio Leukocytes promonocytes to all leukocytes in a biological Measurement specimen.

C74621 PROMONO Promonocytes A measurement of the promonocytes in a biological Promonocyte Count specimen.

C74622 PROMY Promyelocytes A measurement of the promyelocytes (immature Promyelocyte Count myelocytes) in a biological specimen.

C98773 PROMYCE Promyelocytes/ A relative measurement (ratio or percentage) of the Promyelocyte to Total Cell Ratio Total Cells promyelocytes (immature myelocytes) to total cells in Measurement a biological specimen (for example a bone marrow specimen).

C74653 PROMYLE Promyelocytes/ A relative measurement (ratio or percentage) of the Promyelocyte to Lymphocyte Ratio Leukocytes promyelocytes (immature myelocytes) to all Measurement leukocytes in a biological specimen.

C74885 PROPOX Propoxyphene A measurement of the propoxyphene present in a Propoxyphene Measurement biological specimen.

C64858 PROT Protein A measurement of a group of complex organic Total Protein Measurement macromolecules composed of one or more alpha-L-amino acid chains in a biological specimen.

C79463 PROTCRT Protein/ A relative measurement (ratio or percentage) of the Protein to Creatinine Ratio Creatinine protein to creatinine in a biological specimen. Measurement

C92240 PROTOSML Protein/ A relative measurement (ratio or percentage) of total Protein to Osmolality Ratio Osmolality; proteins to the osmolality of a biological specimen. Measurement Protein/ Osmolality Ratio

C100436 PROTS Protein S A measurement of the protein S in a biological Protein S Measurement specimen.

C17634 PSA Prostate Specific A measurement of the prostate specific antigen in a Prostate Specific Antigen Antigen biological specimen. Measurement

C74696 PSDEPHD Pseudoephedrine A measurement of the pseudoephedrine present in a Pseudoephedrine Measurement biological specimen.

C62656 PT Prothrombin A blood clotting measurement that evaluates the Prothrombin Time Time extrinsic pathway of coagulation.

C98774 PTA Prothrombin A measurement of the biological activity of Prothrombin Activity Measurement Activity prothrombin in a biological specimen.

C82034 PTF1_2 Prothrombin A measurement of the prothrombin fragments 1 and 2 Prothrombin Fragments 1 and 2 Fragments 1 + 2 in a biological specimen. Measurement

C81964 PTHCT Parathyroid A measurement of the C-terminal fragment of C-Terminal Parathyroid Hormone Hormone, parathyroid hormone in a biological specimen. Measurement C-Terminal

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 165 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C65047 - LBTESTCD - Laboratory Test Code Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C74784 PTHFG Parathyroid A measurement of the fragmented parathyroid Fragmented Parathyroid Hormone Hormone, hormone in a biological specimen. Measurement Fragmented

C74789 PTHI Parathyroid A measurement of the intact parathyroid hormone in a Intact Parathyroid Hormone Hormone, Intact biological specimen. Measurement

C81965 PTHMM Parathyroid A measurement of the mid-molecule fragment of Mid-Molecule Parathyroid Hormone Hormone, parathyroid hormone in a biological specimen. Measurement Mid-Molecule

C81966 PTHNT Parathyroid A measurement of the N-terminal fragment of N-Terminal Parathyroid Hormone Hormone, parathyroid hormone in a biological specimen. Measurement N-Terminal

C80211 PYRIDNLN Pyridinoline A measurement of the pyridinoline in a biological Pyridinoline Measurement specimen.

C80202 PYY Peptide YY; A measurement of the peptide YY in a biological Peptide YY Measurement Peptide Tyrosine specimen. Tyrosine

C81957 RANTES Reg upon Act A measurement of the RANTES (regulated on Reg upon Act Normal T-cell Exprd Normal T-cell activation, normally, T-cell expressed, and secreted) Secrtd Measurement Exprd Secrtd; chemokine in a biological specimen. Chemokine Ligand 5

C51946 RBC Erythrocytes; A measurement of the total erythrocytes in a Erythrocyte Count Red Blood Cells biological specimen.

C92245 RBCCLMP Erythrocyte Cell A measurement of red blood cell clumps in a Erythrocyte Cell Clumps Clumps; Red biological specimen. Measurement Blood Cell Clumps; RBC Clumps

C96605 RBCGHOST Erythrocyte A measurement of the erythrocyte ghosts Erythrocyte Ghost Count Ghosts; RBC (erythrocytes in which hemoglobin has been removed Ghosts through hemolysis) in a biological specimen.

C92296 RBCMORPH Erythrocyte Cell An examination or assessment of the form and Erythrocyte Cell Morphology Morphology; structure of red blood cells. Red Blood Cell Morphology; RBC Morphology

C74705 RBCNUC Nucleated A measurement of the nucleated erythrocytes (large, Nucleated Red Blood Cell Count Erythrocytes; immature nucleated erythrocytes) in a biological Nucleated Red specimen. Blood Cells

C82046 RBCNUCLE Nucleated A relative measurement (ratio or percentage) of Nucleated Erythrocyte to Leukocyte Erythrocytes/ nucleated erythrocytes to leukocytes in a biological Ratio Measurement Leukocytes specimen.

C74647 RBCNURBC Nucleated A relative measurement (ratio or percentage) of the Nucleated Red Blood Cell to Erythrocytes/ nucleated erythrocytes (large, immature nucleated Erythrocyte Ratio Measurement Erythrocytes; erythrocytes) to all erythrocytes in a biological Nucleated Red specimen. Blood Cells/ Erythrocytes

C100437 RBP Retinol Binding A measurement of the total retinol binding protein in a Retinol Binding Protein Protein biological specimen. Measurement

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 166 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C65047 - LBTESTCD - Laboratory Test Code Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C64800 RDW Erythrocytes A value derived from mean corpuscular volume and the Erythrocyte Distribution Width Distribution standard deviation of the red blood cell volume in a Measurement Width whole blood specimen.

C74893 RENIN Renin; A measurement of the renin in a biological specimen. Renin Measurement Angiotensinogen ase

C80205 RESISTIN Resistin A measurement of the resistin in a biological Resistin Measurement specimen.

C51947 RETI Reticulocytes A measurement of the reticulocytes in a biological Reticulocyte Count specimen.

C98776 RETIHGB Reticulocyte A measurement of the amount of hemoglobin in Reticulocyte Hemoglobin Hemoglobin reticulocytes. Measurement

C64828 RETIRBC Reticulocytes/ A relative measurement (ratio or percentage) of Reticulocyte To Erythrocyte Ratio Erythrocytes reticulocytes to erythrocytes in a biological specimen.

C74717 RF Rheumatoid A measurement of the rheumatoid factor antibody in a Rheumatoid Factor Measurement Factor biological specimen.

C100457 RNPAB Ribonucleoprote A measurement of the ribonucleoprotein antibody in a Ribonucleoprotein Antibody in Antibody; biological specimen. Measurement RNP Antibody

C74624 ROULEAUX Rouleaux A measurement of the number of stacking red blood Rouleaux Formation Count Formation cells within a biological specimen.

C74716 RPR Rapid Plasma A measurement of the antibodies produced by cellular Rapid Plasma Reagin Measurement Reagin damage caused by Treponema pallidum (syphilis) in a biological specimen.

C96628 RPTLTIME Reptilase Time A measurement of the time it takes a plasma sample to Reptilase Time Measurement clot after adding the active enzyme reptilase.

C81968 RT3 Triiodothyronine A measurement of the reverse triiodothyronine in a Reverse Triiodothyronine , Reverse biological specimen. Measurement

C82035 SCF Stem Cell A measurement of the stem cell factor in a biological Stem Cell Factor Measurement Factor; KIT specimen. Ligand

C74706 SCHISTO Schistocytes A measurement of the schistocytes (fragmented red Schistocyte Count blood cells) in a biological specimen.

C74656 SCKCERBC Sickle A relative measurement (ratio or percentage) of the Sickle Cell to Erythrocyte Ratio Cells/ sickle cells (sickle shaped red blood cells) to all Measurement Erythrocytes erythrocytes in a biological specimen.

C74626 SCKLCE Sickle Cells A measurement of the sickle cells (sickle shaped red Sickle Cell Count blood cells) in a biological specimen.

C100458 SCL70AB Scl-70 Antibody; A measurement of the Scl-70 antibody in a biological Scl-70 Antibody Measurement Scleroderma-70 specimen. Antibody

C79465 SDH Sorbitol A measurement of the sorbitol dehydrogenase in a Sorbitol Dehydrogenase Dehydrogenase biological specimen. Measurement

C74871 SECRETIN Secretin A measurement of the secretin hormone in a Secretin Measurement biological specimen.

C74625 SEZCE Sezary Cells A measurement of the Sezary cells (atypical Sezary Cell Count lymphocytes with cerebriform nuclei) in a biological specimen.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 167 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C65047 - LBTESTCD - Laboratory Test Code Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C74655 SEZCELY Sezary A relative measurement (ratio or percentage of the Sezary Cell to Lymphocyte Ratio Cells/ Sezary cells (atypical lymphocytes with cerebriform Measurement Lymphocytes nuclei) to all lymphocytes in a biological specimen.

C74745 SHBG Sex Hormone A measurement of the sex hormone binding (globulin) Sex Hormone Binding Protein Binding protein in a biological specimen. Measurement Globulin; Sex Hormone Binding Protein

C74876 SIXMAM 6-Monoacetylmo A measurement of the 6-monoacetylmorphine present 6-Monoacetylmorphine rphine in a biological specimen. Measurement

C92236 SJSSAAB Ro Antibody; A measurement of the Sjogrens SS-A antibody in a Sjogren's SS-A Antibody Sjogrens SS-A biological specimen. Measurement Antibody

C92237 SJSSBAB La Antibody; A measurement of the Sjogrens SS-B antibody in a Sjogren's SS-B Antibody Sjogrens SS-B biological specimen. Measurement Antibody

C100438 SLTFRNRC Soluble A measurement of the soluble transferrin receptor in a Soluble Transferrin Receptor Transferrin biological specimen. Measurement Receptor

C74627 SMDGCE Smudge Cells; A measurement of the smudge cells (the nuclear Smudge Cell Count Basket Cells remnant of a ruptured white blood cell) in a biological specimen.

C92281 SMTHAB Smith Antibody A measurement of the Smith antibody in a biological Smith Antibody Measurement specimen.

C64809 SODIUM Sodium A measurement of the sodium in a biological Sodium Measurement specimen.

C80360 SOMATRO Somatotrophin; A measurement of the somatotrophin (growth) Somatotropin Measurement Growth hormone in a biological specimen. Hormone

C74663 SPERM Spermatozoa A measurement of the spermatozoa cells present in a Spermatozoa Cell Count biological specimen.

C64832 SPGRAV Specific Gravity A ratio of the density of a fluid to the density of water. Specific Gravity

C74707 SPHERO Spherocytes A measurement of the spherocytes (small, Spherocyte Count sphere-shaped red blood cells) in a biological specimen.

C74872 SRTONIN Serotonin A measurement of the serotonin hormone in a Serotonin Measurement biological specimen.

C96567 STIPBASO Basophilic A measurement of the basophilic stippling in a Basophilic Stippling Measurement Stippling biological specimen.

C74708 STOMCY Stomatocytes A measurement of the stomatocytes (red blood cells Stomatocyte Count with an oval or rectangular area of central pallor, producing the appearance of a cell mouth) in a biological specimen.

C92282 STRPLOAB Streptolysin O A measurement of Streptolysin O Antibody in a Streptolysin O Antibody Antibody; biological specimen. Measurement Antistreptolysin O

C92533 SVCAM1 Soluble Vascular A measurement of the soluble vascular cell adhesion Soluble Vascular Cell Adhesion Cell Adhesion molecule 1 in a biological specimen. Molecule 1 Molecule 1

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 168 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C65047 - LBTESTCD - Laboratory Test Code Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C74747 T3 Triiodothyronine A measurement of the total (free and bound) Triiodothyronine Measurement ; Total T3 triiodothyronine in a biological specimen.

C74787 T3FR Triiodothyronine A measurement of the free triiodothyronine in a Free Triiodothyronine Measurement , Free; Free T3 biological specimen.

C74748 T3UP Triiodothyronine A measurement of the binding of triiodothyonine to Triiodothyronine Uptake Uptake thyroxine binding globulin protein in a biological Measurement specimen.

C74794 T4 Thyroxine; Total A measurement of the total (free and bound) thyroxine Total Thyroxine Measurement T4 in a biological specimen.

C74786 T4FR Thyroxine, Free; A measurement of the free thyroxine in a biological Free Thyroxine Measurement Free T4 specimen.

C74746 TBG Thyroxine A measurement of the thyroxine binding globulin Thyroxine Binding Globulin Protein Binding Globulin protein in a biological specimen. Measurement

C64801 TEARDCY Dacryocytes; A measurement of dacryocytes in a biological Dacryocyte Analysis Tear Shaped specimen. Erythrocytes; Teardrop Cells

C74793 TESTOS Testosterone; A measurement of the total (free and bound) Total Testosterone Measurement Total testosterone in a biological specimen. Testosterone

C74785 TESTOSFR Testosterone, A measurement of the free testosterone in a biological Free Testosterone Measurement Free specimen.

C82037 TFERRIN Transferrin A measurement of the transferrin in a biological Transferrin Measurement specimen.

C98792 TFRRNSAT Transferrin A measurement of the iron bound to transferrin in a Transferrin Saturation Measurement Saturation biological specimen.

C74873 THRMPTN Thrombopoietin A measurement of the thrombopoietin hormone in a Thrombopoietin Measurement biological specimen.

C81990 THYAB Thyroid A measurement of the thyroid antibodies in a Thyroid Antibody Measurement Antibodies biological specimen.

C81991 THYAMAB Thyroid A measurement of the thyroid antimicrosomal Thyroid Antimicrosomal Antibody Antimicrosomal antibodies in a biological specimen. Measurement Antibodies

C81992 THYATAB Thyroid A measurement of the thyroid antithyroglobulin Thyroid Antithyroglobulin Antibody Antithyroglobuli antibodies in a biological specimen. Measurement n Antibodies

C96639 THYPXD Thyroperoxidase; A measurement of the thyroperoxidase in a biological Thyroperoxidase Measurement Thyroid specimen. Peroxidase

C96638 THYPXDAB Thyroperoxidase A measurement of the thyroperoxidase antibody in a Thyroperoxidase Antibody Antibody biological specimen. Measurement

C82036 TIMP1 Tissue Inhibitor A measurement of the tissue inhibitor of Tissue Inhibitor of of metalloproteinase 1 in a biological specimen. Metalloproteinase 1 Measurement Metalloproteinas e 1

C74751 TNF Tumor Necrosis A measurement of the total tumor necrosis factor Tumor Necrosis Factor Factor; Tumor (cachexin) cytokine in a biological specimen. Measurement Necrosis Factor alpha

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 169 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C65047 - LBTESTCD - Laboratory Test Code Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C96641 TOXGRAN Toxic A measurement of the toxic granulation in neutrophilic Toxic Granulation Measurement Granulation blood cells.

C81993 TPAAG Tissue A measurement of the tissue plasminogen activator Tissue Plasminogen Activator Plasminogen antigen in a biological specimen. Antigen Measurement Activator Antigen

C84811 TPRONP Non-Phosphoryl A measurement of the non-phosphorylated Tau protein Nonphosphorylated Tau Protein ated Tau Protein in a biological specimen. Measurement

C84810 TPROT Tau Protein; A measurement of the total Tau protein in a biological Tau Protein Measurement Total Tau Protein specimen.

C84812 TPROTP Phosphorylated A measurement of the phosphorylated Tau protein in a Phosphorylated Tau Protein Tau Protein biological specimen. Measurement

C80208 TRAP Total A measurement of the ability of the antioxidants in a Total Radical-Trap Antioxidant Radical-Trap biological specimen to buffer free radicals in a Potential Measurement Antioxidant suspension. Potential

C100420 TRCYANDP Tricyclic A measurement of tricyclic antidepressants in a Tricyclic Antidepressant Antidepressants biological specimen. Measurement

C96636 TRGTCE Leptocytes; A measurement of the target cells in a biological Target Cell Count Target Cells specimen.

C74874 TRH Thyrotropin A measurement of the thyrotropin releasing hormone Thyrotropin Releasing Hormone Releasing in a biological specimen. Measurement Hormone; Thyrotropin Releasing Factor

C92238 TRICH Trichomonas Examination of a biological specimen to detect the Trichomonas Screening presence of any protozoan belonging to the Trichomonas genus.

C64812 TRIG Triglycerides A measurement of the triglycerides in a biological Triglyceride Measurement specimen.

C74749 TROPONI Troponin I A measurement of the actin binding troponin in a Troponin I Measurement biological specimen.

C74750 TROPONT Troponin T A measurement of the tropomyosin binding troponin in Troponin T Measurement a biological specimen.

C92292 TRYPTASE Tryptase A measurement of the tryptase in a biological Tryptase Measurement specimen.

C64813 TSH Thyrotropin A measurement of the thyrotropin in a biological Thyrotropin Measurement specimen.

C80365 TT Thrombin Time A measurement of the time it takes a plasma sample to Thrombin Time clot after adding the active enzyme thrombin. (NCI)

C74723 TURB Turbidity A measurement of the opacity of a biological Turbidity Measurement specimen.

C64814 URATE Urate; Uric Acid A measurement of the urate in a biological specimen. Urate Measurement

C64815 UREA Urea A measurement of the urea in a biological specimen. Urea Measurement

C96645 UREACRT Urea/Creatinine A relative measurement (ratio or percentage) of the Urea to Creatinine Ratio urea to creatinine in a biological specimen. Measurement

C64816 UROBIL Urobilinogen A measurement of the urobilinogen in a biological Urobilinogen Measurement specimen.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 170 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C65047 - LBTESTCD - Laboratory Test Code Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C82042 VCAM1 Vascular Cell A measurement of the vascular cell adhesion molecule Vascular Cell Adhesion Molecule 1 Adhesion 1 in a biological specimen. Measurement Molecule 1

C92514 VEGF Vascular A measurement of the vascular endothelial growth Vascular Endohelial Growth Factor Endothelial factor in a biological specimen. Measurement Growth Factor

C75912 VISC Viscosity The resistance of a liquid to sheer forces and flow. Viscosity (NCI)

C74895 VITA Vitamin A; A measurement of the Vitamin A in a biological Vitamin A Measurement Retinol specimen.

C74896 VITB1 Thiamine; A measurement of the thiamine in a biological Vitamin B1 Measurement Vitamin B1 specimen.

C64817 VITB12 Vitamin B12 A measurement of the Vitamin B12 in a serum Vitamin B12 Measurement specimen.

C74897 VITB17 Vitamin B17; A measurement of the Vitamin B17 in a biological Vitamin B17 Measurement Amygdalin specimen.

C74898 VITB2 Riboflavin; A measurement of the riboflavin in a biological Vitamin B2 Measurement Vitamin B2 specimen.

C74899 VITB3 Niacin; Vitamin A measurement of the niacin in a biological specimen. Vitamin B3 Measurement B3

C74900 VITB5 Vitamin B5; A measurement of the Vitamin B5 in a biological Vitamin B5 Measurement Pantothenic Acid specimen.

C74901 VITB6 Vitamin B6; A measurement of the Vitamin B6 in a biological Vitamin B6 Measurement Pyridoxine specimen.

C74902 VITB7 Vitamin B7; A measurement of the Vitamin B7 in a biological Vitamin B7 Measurement Biotin specimen.

C74676 VITB9 Folic Acid; A measurement of the folic acid in a biological Folic Acid Measurement Vitamin B9 specimen.

C74903 VITC Vitamin C; A measurement of the Vitamin C in a biological Vitamin C Measurement Ascorbic Acid specimen.

C84818 VITD Vitamin D; Total A measurement of the total Vitamin D in a biological Vitamin D Measurement Vitamin D specimen.

C74904 VITD2 Vitamin D2; A measurement of the Vitamin D2 in a biological Vitamin D2 Measurement Ergocalciferol specimen.

C74905 VITD3 Vitamin D3; A measurement of the Vitamin D3 in a biological Vitamin D3 Measurement Cholecalciferol specimen.

C92267 VITDAT 1, A measurement of the total active Vitamin D in a 1, 25-Dihydroxyvitamin D 25-Dihydroxyvit biological specimen. Measurement amin D; Active Vitamin D

C92268 VITDIT 25-Hydroxyvita A measurement of the total inactive Vitamin D in a 25-Hydroxyvitamin D Measurement min D; Inactive biological specimen. Vitamin D

C74906 VITE Vitamin E; A measurement of the Vitamin E in a biological Vitamin E Measurement Tocopherol specimen.

C74907 VITK Vitamin K; A measurement of the Vitamin K in a biological Vitamin K Measurement Naphthoquinone specimen.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 171 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C65047 - LBTESTCD - Laboratory Test Code Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C64806 VLDL VLDL A measurement of the very low density lipoprotein Serum VLDL Cholesterol Cholesterol cholesterol in a biological specimen. Measurement

C74875 VMA Vanillyl A measurement of the vanillyl mandelic acid Vanillyl Mandelic Acid Mandelic Acid; metabolite in a biological specimen. Measurement Vanilmandelic Acid

C74720 VOLUME Volume A measurement of the volume of a biological Volume Measurement specimen.

C98795 VZVIGAAB Varicella Zoster A measurement of the Varicella Zoster virus IgA Varicella Zoster Virus IgA Antibody Virus IgA antibodies in a biological specimen. Measurement Antibody

C98796 VZVIGGAB Varicella Zoster A measurement of the Varicella Zoster virus IgG Varicella Zoster Virus IgG Antibody Virus IgG antibodies in a biological specimen. Measurement Antibody

C98797 VZVIGMAB Varicella Zoster A measurement of the Varicella Zoster virus IgM Varicella Zoster Virus IgM Antibody Virus IgM antibodies in a biological specimen. Measurement Antibody

C51948 WBC Leukocytes; A measurement of the leukocytes in a biological Leukocyte Count White Blood specimen. Cells

C92246 WBCCLMP Leukocyte Cell A measurement of white blood cell clumps in a Leukocyte Cell Clumps Clumps; White biological specimen. Measurement Blood Cell Clumps; WBC Clumps

C92297 WBCMORPH Leukocyte Cell An examination or assessment of the form and Leukocyte Cell Morphology Morphology; structure of white blood cells. White Blood Cell Morphology; WBC Morphology

C74664 YEAST Yeast Cells A measurement of the yeast cells present in a Yeast Cell Measurement biological specimen.

C92239 YEASTHYP Yeast Hyphae Examination of a biological specimen to detect the Yeast Hyphae Screening presence of any yeast cells that are in the long, filamentous and branching phase of growth.

C80210 ZINC Zinc A measurement of the zinc in a biological specimen. Zinc Measurement

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 172 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C74456 - LOC - Anatomical Location Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C12664 ABDOMINAL CAVITY Abdomen; The portion of the body that lies between the thorax Abdominal Cavity Abdominal and the pelvis. (NCI) Cavity

C52758 ABDOMINAL SKIN Abdominal Skin The skin or integument surrounding the abdomen. Abdominal Skin (NCI)

C32042 ACETABULUM Acetabulum Two cup shaped areas, one each on the lateral side of Acetabulum the lower pelvis that house the head of the femur to form the ball and socket joint of the hip. (NCI)

C32047 ACROMIOCLAVICULAR Acromioclavicul The junction of the upper distal end of the scapula to Acromioclavicular Joint JOINT ar Joint the distal edge of the collarbone, also known as the acromion and the clavicle. (NCI)

C32048 ACROMION Acromion The upper distal process of the scapula. (NCI) Acromion

C12666 ADRENAL GLAND Adrenal Gland Suprarenal gland. A flattened, roughly triangular body Adrenal Gland resting upon the upper end of each kidney; it is one of the ductless glands furnishing internal secretions (epinephrine and norepinephrine from the medulla and steroid hormones from the cortex). (NCI)

C15609 ANASTOMOSIS Anastomosis A natural or surgically-induced connection between Anastomosis tubular structures in the body. (NCI)

C32078 ANKLE JOINT Ankle Joint; A gliding joint between the distal ends of the tibia and Ankle Joint Ankle fibula and the proximal end of the talus. (NCI)

C12259 ANTRUM PYLORI Antrum Pylori The initial part of the pyloric canal of the stomach. Antrum Pylori This site contains endocrine cells that produce gastrin and somatostatin. (NCI)

C43362 ANUS Anus The lower opening of the digestive tract, lying in the Anus cleft between the buttocks, through which fecal matter is extruded. (NCI)

C12669 AORTA Aorta The major arterial trunk that carries oxygenated blood Aorta from the left ventricle into the ascending aorta behind the heart, the aortic arch, through the thorax as the descending aorta and through the abdomen as the abdominal aorta; it bifurcates into the left and right common iliac arteries. (NCI)

C32123 AORTIC ARCH Aortic Arch The curved section of the aorta between the ascending Aortic Arch and the descending tracts. The brachiocephalic, left common carotid and left subclavian arteries branch from the aorta at this section. (NCI)

C83470 APPENDICEAL TIP The distal end of the appendix. (NCI) Appendiceal Tip

C12380 APPENDIX Appendix Small tissue projection existing as a cecal Appendix diverticulum with a questionable history of vestigial versus specialized organ. (NCI)

C32141 ARM Arm The portion of the upper extremity between the Arm shoulder and the elbow. For clinical purposes this term is also used to refer to the whole superior limb. (NCI)

C52754 ARM SKIN Arm Skin The skin or integument covering the arm. (NCI) Arm Skin

C12372 ARTERY Artery A blood vessel that carries blood away from the heart. Artery (NCI)

C12674 AXILLA Axilla The underside concavity where the arm and the Axilla shoulder are joined. (NCI)

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 173 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C74456 - LOC - Anatomical Location Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C12904 AXILLARY LYMPH NODE Axillary Lymph One of approximately 20-30 lymph nodes in chain Axillary Lymph Node Node formation that traverse the concavity of the underarm to the clavicle. (NCI)

C13062 BACK Back The dorsal area between the base of the neck and the Back sacrum. (NCI)

C12447 BASAL GANGLIA Basal Ganglia Clusters of neurons comprising the globus pallidus, Basal Ganglia putamen, caudate, nucleus accumbens, substantia nigra and subthalamic nucleus. They are involved with high level aspects of inhibitory motor activity in coordination with the excitation commands issued from the cerebellum. (NCI)

C32197 BASILIC VEIN Basilic Vein One of the moderately large superficial veins of the Basilic Vein forearm that transports blood from the hand and the medial aspect of the forearm to the axillary vein. (NCI)

C12678 BILIARY TRACT Biliary Tract The duct system that transports bile from its Biliary Tract origination by hepatocytes in the liver to the small intestine. It is comprised of the common bile duct that connects the liver and gall bladder to the small intestine and the cystic duct that connects the gall bladder to the common bile duct. (NCI)

C12414 BLADDER Bladder The distensible sac-like organ that functions as a Bladder reservoir of urine, collecting from the kidneys and eliminating via the urethra. (NCI)

C12332 BLADDER, DOME Dome of the The upper, convex surface of the bladder. (NCI) Dome of the Bladder Bladder

C48939 BLADDER, FUNDUS Fundus of the The portion of the bladder that is formed by the Bladder Fundus Bladder posterior wall and is located opposite to the bladder opening. (NCI)

C12336 BLADDER, NECK Neck of the The inferior portion of the urinary bladder which is Bladder Neck Bladder formed as the walls of the bladder converge and become contiguous with the proximal urethra. (NCI)

C12331 BLADDER, TRIGONE Trigone of the The triangular area in the bladder mucosa that is Bladder Trigone Bladder formed by the two ureteral orifices and the urethral orifice. (NCI)

C12434 BLOOD Blood A liquid tissue; its major function is to transport Blood oxygen throughout the body. It also supplies the tissues with nutrients, removes waste products, and contains various components of the immune system defending the body against infection. Several hormones also travel in the blood. (NCI)

C12679 BLOOD VESSEL Blood Vessel A tubular structure through which the blood circulates Blood Vessel in the body. Blood vessels constitute a network composed of arteries, arterioles, capillaries, venules, and veins. (NCI)

C13041 BODY Body The entire physical structure of an organism. It is Body composed of anatomic systems, regions, cavities, and spaces. (NCI)

C12258 BODY OF STOMACH Body of Stomach The main section of the digestive tube that connects Body of Stomach the esophagus to the small intestine. The body proper excludes the upper and lower sections of the fundus and pyloric portion respectively. (NCI)

C12366 BONE Bone Connective tissue that forms the skeletal components Bone of the body. (NCI)

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 174 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C74456 - LOC - Anatomical Location Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C12431 BONE MARROW Bone Marrow The tissue occupying the spaces of bone. It consists of Bone Marrow blood vessel sinuses and a network of hematopoietic cells which give rise to the red cells, white cells, and megakaryocytes. (NCI)

C12681 BRACHIAL ARTERY Brachial Artery An artery originating at the axillary artery and Brachial Artery branching into the radial and ulnar arteries. (NCI)

C12682 BRACHIAL PLEXUS Brachial Plexus A nerve network originating from C5 to T1 that Brachial Plexus supplies cutaneous and muscular innervation to the arm and hand. (NCI)

C12439 BRAIN Brain; Nervous An organ composed of grey and white matter Brain System, Brain containing billions of neurons that is the center for intelligence and reasoning. It is protected by the bony cranium. (NCI)

C12441 BRAIN STEM Brain Stem The part of the brain that connects the cerebral Brain Stem hemispheres with the spinal cord. It consists of the mesencephalon, pons, and medulla oblongata. (NCI)

C12356 BRAIN VENTRICLE Brain Ventricle The four connected cavities (hollow spaces) centrally Brain Ventricle located within the brain that connect posteriorly with the central canal of the spinal cord. (NCI)

C12971 BREAST Breast One of two hemispheric projections of variable size Breast situated in the subcutaneous layer over the pectoralis major muscle on either side of the chest. (NCI)

C12683 BRONCHUS Bronchi; Tubular structure in continuation with the trachea, Bronchus Bronchus serving as air passage. It terminates in the lung (terminal bronchiole). (NCI)

C89806 BUTTOCK Buttock Either of the fleshy mounds in the rear pelvic area of Buttock the human body formed by the gluteal muscles.

C32239 C1 VERTEBRA C1 Vertebra The first of the seven cervical vertebrae. (NCI) C1 Vertebra

C32240 C2 VERTEBRA C2 Vertebra The second of the seven cervical vertebrae. (NCI) C2 Vertebra

C32241 C3 VERTEBRA C3 Vertebra The third of the seven cervical vertebrae. (NCI) C3 Vertebra

C32242 C4 VERTEBRA C4 Vertebra The fourth of the seven cervical vertebrae. (NCI) C4 Vertebra

C32243 C5 VERTEBRA C5 Vertebra The fifth of the seven cervical vertebrae. (NCI) C5 Vertebra

C32244 C6 VERTEBRA C6 Vertebra The sixth of the seven cervical vertebrae. (NCI) C6 Vertebra

C32245 C7 VERTEBRA C7 Vertebra The seventh of the seven cervical vertebrae. (NCI) C7 Vertebra

C32252 CALCARINE SULCUS A cerebral fissure that originates near the occipital Calcarine Sulcus lobe and terminates below the corpus callosum. (NCI)

C32258 CANINE TOOTH Canine Tooth A single-cusped (pointed) and usually single-rooted Canine Tooth tooth located between the incisors and premolars. (NCI)

C12856 CAPITATE BONE Capitate Bone The largest of eight carpal bones, located in the center Capitate Bone of the hand. (NCI)

C12371 CARDIAC MUSCLE TISSUE Myocardium The striated muscle tissue of the heart enveloped by Myocardium the epicardium and the endocardium. (NCI)

C12687 CAROTID ARTERY Carotid Artery One of two arteries that supply oxygenated blood to Carotid Artery the head and neck; the left common carotid branches from the aorta and the right common carotid from the innominate (brachiocephalic artery). (NCI)

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 175 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C74456 - LOC - Anatomical Location Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C12381 CECUM Cecal; Cecum A blind pouch-like commencement of the colon in the Cecum right lower quadrant of the abdomen at the end of the small intestine and the start of the large intestine. (NCI)

C65166 CELIAC LYMPH NODE Celiac Lymph A lymph node at the base of the celiac artery. (NCI) Celiac Lymph Node Node

C32286 CEPHALIC VEIN Cephalic Vein; One of five superficial veins of the upper extremity, Cephalic Vein Vena Cephalica beginning at the radial aspect of the wrist area, wrapping around the forearm and emptying into the axillary vein. (NCI)

C12445 CEREBELLUM The portion of the brain located at the base of the skull Cerebellum that is responsible for balance, equilibrium and movement. (NCI)

C12443 CEREBRAL CORTEX Cerebral Cortex The outer layer of the cerebrum composed of neurons Cortex and unmyelinated nerve fibers. It is responsible for memory, attention, consciousness and other higher levels of mental function.

C98712 CEREBRAL SUBCORTEX Cerebral The layer located below the cerebral cortex that Cerebral Subcortex Subcortex includes the forebrain, midbrain and hindbrain. (NCI)

C12351 CEREBRUM Cerebral One half of the cerebrum, the part of the brain that Cerebral Hemisphere Hemisphere controls muscle functions and also controls speech, thought, emotions, reading, writing, and learning. The right hemisphere controls the muscles on the left side of the body, and the left hemisphere controls the muscles on the right side of the body. (NCI)

C32298 CERVICAL LYMPH NODE Cervical Lymph Any of the lymph nodes located in the neck. (NCI) Cervical Lymph Node Node

C12693 CERVICAL VERTEBRA Cervical Any one of the seven vertebrae that start with C1, Cervical Vertebra Vertebra connecting the skull to the spine, and ends with C7, which joins the cervical with the thoracic spine. (NCI)

C12311 CERVIX UTERI Cervix Uteri; The lower part of the uterus occupying the region Cervix Uteri Uterine Cervix between the isthmus of the uterus and the vagina. It is divided into supravaginal and vaginal portions. (NCI)

C25389 CHEST Chest The anterior side of the thorax from the neck to the Chest abdomen. The shape of the chest is often regarded as potential insight into a disease process, as in the case of barrel chest and respiratory dysfunction. (NCI)

C62484 CHEST WALL Chest Wall The total system of structures outside the lungs that Chest Wall move as a part of breathing; it includes all structures from the skin to the parietal pleura. (NCI)

C12694 CHOROID PLEXUS Choroid Plexus Blood vessels forming villous structures in the third, Choroid Plexus fourth, and lateral ventricles of the brain. (NCI)

C12695 CLAVICLE Clavicle One of a pair of bones linking the scapula and the Clavicle sternum. The clavicle is part of the pectoral girdle. (NCI)

C32334 COCCYGEAL VERTEBRA Coccygeal Four vertebral segments positioned at the base of the Coccygeal Vertebra Vertebra spine that are fused. (NCI)

C12696 COCCYX Coccyx A small bone located at the bottom of the spine. The Coccyx coccyx is a result of 3-5 fused rudimentary vertebrae. (NCI)

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 176 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C74456 - LOC - Anatomical Location Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C12382 COLON Colon The part of the large intestine measured from the Colon cecum to the rectum consisting of ascending, transverse, descending and sigmoid portions. The purpose of the colon is to remove water from digested food prior to excretion. (NCI)

C12265 COLON, ASCENDING Ascending Colon The first part of the colon (large intestine) that starts Ascending Colon in the right lower quadrant of the abdomen and ends at the transverse colon in the right upper quadrant of the abdomen. (NCI)

C12268 COLON, DESCENDING Descending The fourth portion of the large intestine (colon) that Descending Colon Colon communicates with the transverse colon in the left-upper quadrant of the abdomen and the rectum below. (NCI)

C33929 COLON, LEFT Left Colon The portion of the large intestine that includes the Left Colon descending and sigmoid colon. (NCI)

C12383 COLON, RIGHT Right Colon The proximal segment of the large intestine that is Right Colon located in the right side of the abdominal cavity. It includes the cecum (with the attached appendix) and the ascending colon. (NCI)

C12384 COLON, SIGMOID Sigmoid Colon The portion of the colon that connects to the Sigmoid Colon descending colon above and the rectum below. (NCI)

C12385 COLON, TRANSVERSE Transverse Colon The third division of the colon (large intestine). It Transverse Colon communicates with the ascending colon in the upper right-hand quadrant of the abdomen and the descending colon in the upper left-hand quadrant. (NCI)

C12341 CONJUNCTIVA Conjunctiva A thin, transparent tissue divided into the palpebral Conjunctiva conjunctiva (covering the inner side of the eye lid) and the bulbar conjunctiva (covering the eyeball). (NCI)

C12342 CORNEA Cornea A dome-shaped, transparent, avascular tissue covering Cornea the front of the eye. It is composed of five layers: squamous epithelium, Bowman's membrane, stroma, Descemet's membrane, and endothelium. Refraction of light contributing to eye's focusing ability is its characteristic function. It contains unmyelinated nerve endings which are responsible for the high sensitivity of the tissue. (NCI)

C12843 CORONARY ARTERY Coronary Artery A principal artery that originates in the aorta. It Coronary Artery supplies blood to the muscular tissue of the heart. (NCI)

C32089 CORONARY ARTERY, Anterior A left coronary artery branch that descends on the Anterior Descending Coronary ANTERIOR DESCENDING Descending anterior portion of the heart through the anterior Artery Coronary Artery interventricular groove. (NCI)

C12872 CORONARY ARTERY, LEFT Left Coronary A coronary artery that arises from the aorta and Left Coronary Artery Artery bifurcates into the left anterior descending artery and the left circumflex artery. (NCI)

C12875 CORONARY ARTERY, Right Coronary A coronary artery that originates above the right Right Coronary Artery RIGHT Artery coronary cusp and supplies blood predominantly to the right side of the heart. (NCI)

C26465 CORPUS LUTEUM Corpus Luteum A group of cells that remain of the Graafian follicle Corpus Luteum following ovulation. This structure is composed of endocrine tissue and produces progesterone. This is needed to prepare the uterine lining for implantation by the fertilized egg. (NCI)

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 177 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C74456 - LOC - Anatomical Location Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C32391 COSTAL CARTILAGE Costal Cartilage The cartilage positioned between the anterior end of Costal Cartilage the rib and the sternum. Its elasticity allows the ribcage to expand while breathing. (NCI)

C32414 CUBOID BONE Cuboid Bone A bone on the lateral side of the tarsus between the Cuboid Bone calcaneus and the fourth and fifth metatarsal bones. (NCI)

C32478 DORSALIS PEDIS ARTERY Dorsalis Pedis An artery of the dorsal surface of the foot, originating Dorsalis Pedis Artery Artery from the anterior tibial artery of the lower leg. The following arterial branches originate from the dorsalis pedis artery: the arcuate artery of the foot and deep plantar artery. (NCI)

C12263 DUODENUM A jointed tube 25-30 cm long that connects the Duodenum stomach to the jejunum. (NCI)

C12394 EAR Ear A sense organ needed for the detection of sound and Ear for establishing balance. The outer ear consists of the auricle, the ear canal as well as the tympanic membrane. The middle ear is made up of an air-filled cavity behind the tympanic membrane that contains the ossicles (malleus, incus and stapes). The inner ear is made up of the cochlea needed for hearing and the vestibular apparatus required for balance. (NCI)

C12499 EAR, INNER Cochlea; Internal The portion of the ear located within the temporal Internal Ear Ear; Labyrinth bone that is involved in both hearing and balance and includes the semicircular canals, vestibule, and cochlea. (from American Heritage Dictionary online)

C12292 EAR, OUTER Auricle; External The external part of the ear. (NCI) External Ear Ear

C32497 ELBOW JOINT Elbow Joint A type of hinge joint located between the forearm and Elbow Joint upper arm. (NCI)

C13004 ENDOCARDIUM The layer of endothelial cells and connective tissue Endocardium lining the chambers of the heart. (NCI)

C32514 ENDOMETRIAL CAVITY Endometrial A space inside the uterus lined by a layer of mucus Endometrial Cavity Cavity membranes called the endometrium. (NCI)

C13164 EPICARDIUM The outer membranous connective tissue layer of the Epicardium heart tissue. (NCI)

C69300 EPICONDYLE Epicondyle A bone prominence to which ligaments and tendons of Epicondyle the joints are attached. (NCI)

C12328 EPIDIDYMIS A crescent-like structure located in the upper and Epididymis posterior surfaces of the testis. It consists of the efferent ductules and the duct of the epididymis. It facilitates the maturation of sperm that is produced in the testis. (NCI)

C12709 EPIGLOTTIS Epiglottis A small cartilagenous flap-like valve that closes over Epiglottis the larynx during swallowing to prevent food entering the lungs. (NCI)

C12389 ESOPHAGUS Esophagus The portion of the digestive canal between the pharynx Esophagus and stomach. It is about 25 cm long and consists of three parts: the cervical part, from the cricoid cartilage to the thoracic inlet; thoracic part, from thoracic inlet to the diaphragm; and abdominal part, below the diaphragm to the cardiac opening of the stomach. (NCI)

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 178 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C74456 - LOC - Anatomical Location Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C12252 ESOPHAGUS, ABDOMINAL Abdominal Clinical esophageal segment composed of smooth Abdominal Esophagus Esophagus muscle. It corresponds to the inferior part of the lower third topographic segment of the esophagus. (NCI)

C12250 ESOPHAGUS, CERVICAL Cervical Clinical esophageal segment composed of skeletal Cervical Esophagus Esophagus muscle. It corresponds to the superior part of the upper third topographic segment of the esophagus. (NCI)

C12255 ESOPHAGUS, LOWER Lower Third of The lower one third of the esophagus in which the Lower Third of the Esophagus THIRD the Esophagus muscle layer is composed of muscle cells predominantly of the smooth type. (NCI)

C12254 ESOPHAGUS, MIDDLE Middle Third of The middle one third of the esophagus in which the Middle Third of the Esophagus THIRD the Esophagus muscle layer is composed of muscle cells of the striated and smooth types.

C12251 ESOPHAGUS, THORACIC Thoracic Clinical esophageal segment composed of smooth Thoracic Esophagus Esophagus muscle. It includes the middle third topographic segment, as well as parts of the upper and lower thirds. (NCI)

C12253 ESOPHAGUS, UPPER Upper Third of The upper one third of esophagus in which the muscle Upper Third of the Esophagus THIRD the Esophagus layer is composed of muscle cells of the striated type. (NCI)

C12711 ETHMOID BONE Ethmoid Bone A light and spongy bone that is cubical in shape. This Ethmoid Bone bone is positioned at the anterior part of the cranium, sitting between the two orbits, at the roof of the nose. It consists of four parts: a horizontal or cribriform plate; a perpendicular plate; and two lateral masses or labyrinths. (NCI)

C12276 ETHMOID SINUS Ethmoid Sinus A sinus of the meatuses of the nasal cavity. (NCI) Ethmoid Sinus

C32573 EXTRAHEPATIC BILE DUCT The portion of the biliary tract outside the liver; the Extrahepatic Bile Duct common hepatic duct joins the cystic duct to form the common bile duct. (NCI)

C12401 EYE Eye; Eyeball The organ of sight or vision. (NCI) Eye

C32576 EYELASH Anyone of the short hairs that grow on the edge of the Eyelash eyelid. (NCI)

C12713 EYELID Eyelid; Palpebra A thin membrane of skin with the purpose of covering Eyelid and protecting an eye. (NCI)

C13071 FACE Face; Facial The anterior portion of the head extending from the Face forehead to the chin and ear to ear. The facial structures contain the eyes, nose and mouth, cheeks and jaws. (NCI)

C32577 FACET JOINT Facet Joint A synovial joint between two adjacent vertebrae. The Facet Joint facet joint links the articular process of one vertebra and the inferior articular process of the adjacent vertebra. (NCI)

C63706 FACIAL BONE Facial Bone Any bone that contributes to the facial structures, Facial Bone except those bones that are part of the braincase. (NCI)

C12403 FALLOPIAN TUBE Fallopian Tube One of a pair of tubes that extend from the uterus to Fallopian Tube each of the ovaries. Following ovulation the egg travels down the fallopian tube to the uterus where fertilization may or may not occur. (NCI)

C61600 FEMALE GENITALIA Female Genitalia Female internal and external organs of reproduction. Female Genitalia

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 179 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C74456 - LOC - Anatomical Location Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C12715 FEMORAL ARTERY Femoral Artery An artery that starts within the inguinal region and Femoral Artery extends to the lower extremities. (NCI)

C61563 FEMORAL NECK Femoral Neck The short, constricted portion of the thigh bone Femoral Neck between the femur head and the trochanter. (NCI)

C12716 FEMORAL VEIN Femoral Vein A vein that starts within the inguinal region and extends Femoral Vein to the lower extremities. (NCI)

C12717 FEMUR Bone, Femoral; The upper leg bone positioned between the pelvis and Femur Femur the knee. (NCI)

C12718 FIBULA Fibula The small, lateral calf bone extending from the knee to Fibula the ankle. (NCI)

C32608 FINGER Finger Any of the digits of the hand. (NCI) Finger

C32609 FINGERNAIL Fingernail The nail at the end of a finger. (NCI) Fingernail

C32622 FOOT Feet; Foot The structure found below the ankle joint required for Foot locomotion. (NCI)

C52772 FOOT PHALANX Foot Phalanx A bone of the foot. (NCI) Foot Phalanx

C32628 FOREARM Forearm The structure on the upper limb, between the elbow and Forearm the wrist. (NCI)

C40185 FOREBRAIN The largest part of the brain composed of the cerebral Forebrain hemispheres, thalamus, hypothalamus, and the limbic system. (NCI)

C89803 FOREHEAD Forehead The part of the face between the eyebrows and the Forehead normal hairline.

C12352 FRONTAL LOBE Frontal Lobe The part of the brain located anterior to the parietal Frontal Lobe lobes at the front of each cerebral hemisphere. (NCI)

C12277 FRONTAL SINUS Frontal Sinus The paired, mucosal lined air spaces located above the Frontal Sinus orbit and communicating with the nasal passages. (NCI)

C12257 FUNDUS OF THE STOMACH Fundus of the The portion of the stomach that lies above the cardiac Fundus of the Stomach Stomach notch. It allows for the accumulation of gases produced by chemical digestion. (NCI)

C12377 GALLBLADDER Gallbladder A pear-shaped organ located under the liver that stores Gallbladder and concentrates bile secreted by the liver. From the gallbladder the bile is delivered through the bile ducts into the intestine thereby aiding the digestion of fat-containing foods. (NCI)

C12719 GANGLION Ganglia; A cluster of nervous tissue principally composed of Ganglion Ganglion; Neural neuronal cell bodies external to the central nervous Ganglion system (CNS). (NCI)

C13307 GASTRIC Gastric Relating to the stomach. (NCI) Gastric

C12256 GASTRIC CARDIA Gastric Cardia The area around the esophagogastric mucosal junction Gastric Cardia where the esophageal mucosa transitions into the gastric mucosa. (NCI)

C32668 GASTROESOPHAGEAL Gastroesophagea The anatomical location where the esophagus joins to Gastroesophageal Junction JUNCTION l Junction the stomach. (NCI)

C12378 GASTROINTESTINAL Gastrointestinal The system that includes the esophagus, stomach, Gastrointestinal System SYSTEM System small and large intestine, anus, liver, biliary tract, and pancreas. (NCI)

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 180 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C74456 - LOC - Anatomical Location Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C34082 GASTROINTESTINAL Gastrointestinal The upper gastrointestinal (GI) tract is comprised of Gastrointestinal Tract TRACT Tract mouth, pharynx, esophagus and stomach while the lower GI tract consists of intestines and anus. The primary function of the GI tract is to ingest, digest, absorb and ultimately excrete food stuff. (NCI)

C33010 GASTROINTESTINAL Lower The lower part of the gastrointestinal tract that Lower Gastrointestinal Tract TRACT, LOWER Gastrointestinal includes the jejunum and ileum of the small intestine Tract and the large intestine. (NCI)

C33837 GASTROINTESTINAL Upper The upper part of the gastrointestinal tract that Upper Gastrointestinal Tract TRACT, UPPER Gastrointestinal includes the esophagus, stomach, and duodenum. (NCI) Tract

C32677 GINGIVA Gingiva; Gum The soft tissue surrounding the neck of individual teeth Gingiva as well as covering the alveolar bone. The tissue is fibrous and continuous with the periodontal ligament and mucosal covering. (NCI)

C32682 GLENOID FOSSA Glenoid Fossa The trough in the head of the scapula that receives the Glenoid Fossa head of the humerus to form the shoulder joint. (NCI)

C12724 GLOTTIS Glottis The space in which the vocal cords are located. (NCI) Glottis

C32698 GREAT TROCHANTER Great Trochanter A large, irregular, quadrilateral area of bone found at Great Trochanter the neck of the femur. (NCI)

C12262 GREATER CURVATURE OF Greater The lateral and inferior border of the stomach. Greater Curvature of the Stomach THE STOMACH Curvature of the Attached to it is the greater omentum. (NCI) Stomach

C32705 HAIR Hair The filamentous outgrowth of the epidermis. (NCI) Hair

C32706 HAIR BULB The lower segment of the hair that circles the dermal Hair Bulb papilla and the hair matrix. (NCI)

C13317 HAIR FOLLICLE A tube-like invagination of the epidermis from which Hair Follicle the hair shaft develops and into which the sebaceous glands open; the follicle is lined by a cellular inner and outer root sheath of epidermal origin and is invested with a fibrous sheath derived from the dermis. (NCI)

C32711 HAIR ROOT The portion of the hair that is enclosed within the hair Hair Root follicle. (NCI)

C33543 HAIR SHAFT Shaft of the Hair The segment of the hair that projects above the skin Shaft of the Hair surface. (NCI)

C12860 HAMATE BONE Hamate Bone The medial bone in the distal row of carpal bones. Hamate Bone (NCI)

C32712 HAND Hand The distal portion of the upper extremity. It consists of Hand the carpus, metacarpus, and digits. (NCI)

C52771 HAND PHALANX Hand Phalanx A bone of the hand. (NCI) Hand Phalanx

C12230 HARD PALATE Hard Palate The bony anterior part of the roof of the mouth Hard Palate separating the nose from the mouth. (NCI)

C12419 HEAD Head The anterior and superior part of a human or animal Head bearing the mouth, the brain and sensory organs.

C32720 HEAD OF THE HUMERUS Head of the The upper rounded part of the humerus that fits into the Head of the Humerus Humerus glenoid cavity of the scapula. (NCI)

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 181 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C74456 - LOC - Anatomical Location Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C12727 HEART Cardiac; Heart A hollow muscular organ which receives the blood Heart from the veins and propels it into the arteries. It is divided by a musculomembranous septum into two halves -- right or venous and left or arterial -- each of which consists of a receiving chamber (atrium) and an ejecting chamber (ventricle). (NCI)

C32126 HEART, APEX Apex of the The most outer superficial part of the heart which is Apex of the Heart Heart situated on the left 5th intercostal space. (NCI)

C12728 HEART, ATRIUM Cardiac Atrium The paired upper chambers of the heart. The left atrium Cardiac Atrium receives oxygenated blood from the pulmonary vein and pumps blood into the left ventricle. The right atrium receives venous deoxygenated blood from the entire body via the superior and inferior vena cavae and pumps blood into the right ventricle. (NCI)

C48589 HEART, BASE Base of the Heart The superior portion of the heart located opposite to Base of the Heart the apical portion. It is formed mainly by the left atrium. (NCI)

C12871 HEART, LEFT VENTRICLE Left Ventricle The left lower chamber of the heart that receives blood Left Ventricle from the left atrium and pumps it through the aorta to the body. (NCI)

C12870 HEART, RIGHT VENTRICLE Right Ventricle The lower chamber of the heart located in the right Right Ventricle side. It receives blood from the right atrium that is no longer oxygenated and it pumps it to the pulmonary artery. (NCI)

C49485 HEART, SEPTUM Cardiac Septum The tissue in the heart that separates the two atria Heart Septum (atrial septum) and the two ventricles (ventricular septum). (NCI)

C12730 HEART, VENTRICLE Cardiac The lower right and left chambers of the heart. The Cardiac Ventricle Ventricle right pumps venous blood into the lungs and the left pumps oxygenated blood into the systemic arterial circulation. (MeSH)

C13308 HEPATIC Hepatic Pertaining to, affecting, or associated with the liver. Hepatic (NCI)

C25724 HILAR Hilar Refers to the area associated with the hilum. (NCI) Hilar

C64193 HIP Hip The lateral prominence of the pelvis from the waist to Hip the thigh. (NCI)

C32742 HIP JOINT Coxofemoral A ball-and-socket joint between the head of the femur Hip Joint Joint; Hip Joint and the acetabulum. (NCI)

C12444 HIPPOCAMPUS Hippocampus A curved gray matter structure of the temporal lobe Hippocampus lying on the floor of the lateral ventricle of the brain. (NCI)

C12731 HUMERUS Bone, Humeral; The upper arm bone between the shoulder and elbow. Humerus Humerus (NCI)

C32752 HYOID BONE Hyoid Bone A U-shaped bone supporting the tongue. This bone is Hyoid Bone located at the base of the tongue and is suspended from the tips of the styloid processes of the temporal bones by the stylohyoid ligaments. (NCI)

C12246 HYPOPHARYNX Hypopharynx The lower part of the pharynx that connects to the Hypopharynx esophagus. (NCI)

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 182 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C74456 - LOC - Anatomical Location Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C12458 HYPOTHALAMUS Hypothalamus The supervisory center in the brain, rich in ganglia, Hypothalamus nerve fibers, and synaptic connections. It is composed of several sections called nuclei, each of which controls a specific function.

C12387 ILEUM Ileum The final section of the small intestine. (NCI) Ileum

C33757 ILEUM, TERMINAL Terminal Ileum The most distal section of the ileum that is continuous Terminal Ileum with the cecum. (NCI)

C32761 ILIAC LYMPH NODE Iliac Lymph One of the three lymph nodes of the pelvis: the Iliac Lymph Node Node superior gluteal, interior gluteal or sacral. (NCI)

C32765 ILIUM Ilium The broad, dorsal, upper, and widest of the three Ilium principal bones composing either half of the pelvis. (NCI)

C32769 INCISOR Incisor One of the teeth in front of the canines in either jaw Incisor designed for cutting or gnawing. (NCI)

C32770 INCUS Incus One of the three bones comprising the middle ear. This Incus anvil-shaped bone is positioned between the malleus and the stapes. (NCI)

C63705 INFRACLAVICULAR Infraclavicular A lymph node located in the area below the clavicle. Infraclavicular Lymph Node LYMPH NODE Lymph Node (NCI)

C32801 INGUINAL LYMPH NODE Inguinal Lymph A superficial or deep lymph node located in the Inguinal Lymph Node Node inguinal area. (NCI)

C12726 INGUINAL REGION Inguinal Region The lower region of the anterior abdominal wall Inguinal Region located laterally to the pubic region. (NCI)

C32868 INTERPHALANGEAL JOINT Interphalangeal The hinge synovial joints between the phalanges of the Interphalangeal Joint of the Hand OF THE HAND Joint of the Hand fingers. (NCI)

C12736 INTESTINE Intestine The portion of the gastrointestinal tract between the Intestine stomach and the anus. It includes the small intestine and large intestine. (NCI)

C12677 INTRAHEPATIC BILE DUCT The bile ducts that pass through and drain bile from the Intrahepatic Bile Duct liver. (NCI)

C32884 ISCHIUM Ischium The most posterior and ventral bone making up the Ischium pelvis. (NCI)

C32888 JAW JOINT Jaw Joint The joint between the head of the lower mandible and Jaw Joint the temporal bone. (NCI)

C12388 JEJUNUM Jejunum The portion of the small intestine that extends from Jejunum the duodenum to the ileum. (NCI)

C13044 JOINT Articulation; The connection point between two bones or skeletal Joint Joint elements. The joint may be fixed or movable. (NCI)

C12415 KIDNEY Kidney One of the two bean-shaped organs located on each Kidney side of the spine in the retroperitoneum. The right kidney is located below the liver and the left kidney below the diaphragm. The kidneys filter and secret the metabolic products and minerals from the blood, thus maintaining the homeostasis. On the superior pole of each kidney there is an adrenal gland. Each kidney and adrenal gland is surrounded by fat. (NCI)

C12739 KIDNEY, CORTEX Renal Cortex The outer zone of the KIDNEY, beneath the capsule, Renal Cortex consisting of KIDNEY GLOMERULUS; KIDNEY TUBULES, DISTAL; and KIDNEY TUBULES, PROXIMAL. (MSH2001)

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 183 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C74456 - LOC - Anatomical Location Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C32740 KIDNEY, HILUM Hilar Area of the The concave area of the kidney through which the renal Hilar Area of the Kidney Kidney artery enters and the renal vein and ureter exit the organ. (NCI)

C93180 KIDNEY, LOWER LOBE Lower Lobe of The lobe of the kidney located in the lowest portion of Lower Lobe of Kidney the Kidney the kidney. (NCI)

C12740 KIDNEY, MEDULLA Renal Medulla The internal portion of the kidney, consisting of Renal Medulla striated conical masses, the renal pyramids, whose bases are adjacent to the cortex and whose apices form prominent papillae projecting into the lumen of the minor calyces. (MSH2001)

C93179 KIDNEY, UPPER LOBE Upper Lobe of The lobe of the kidney located in the uppermost region Upper Lobe of Kidney the Kidney of the kidney. (NCI)

C32898 KNEE JOINT Knee Joint; A joint connecting the lower part of the femur with the Knee Joint Tibiofemoral upper part of the tibia. The lower part of the femur and Joint the upper part of the tibia are attached to each other by ligaments. Other structures of the knee joint include the upper part of the fibula, located below and parallel to the tibia, and the patella which moves as the knee bends. (NCI)

C32899 L1 VERTEBRA L1 Vertebra The first lumbar vertebra counting from the top down. L1 Vertebra (NCI)

C32900 L2 VERTEBRA L2 Vertebra The second lumbar vertebra counting from the top L2 Vertebra down. (NCI)

C32901 L3 VERTEBRA L3 Vertebra The third lumbar vertebra counting from the top down. L3 Vertebra (NCI)

C32902 L4 VERTEBRA L4 Vertebra The fourth lumbar vertebra counting from the top L4 Vertebra down. (NCI)

C32903 L5 VERTEBRA L5 Vertebra The fifth lumbar vertebra counting from the top down. L5 Vertebra (NCI)

C32906 LACRIMAL BONE Lacrimal Bone A small rectangular thin plate forming part of the Lacrimal Bone medial orbit wall. It is located posterior to the frontal process of the maxilla and articulates with the inferior nasal concha, ethmoid, frontal, and maxillary bones. (NCI)

C12379 LARGE INTESTINE Large Intestine A muscular tube that extends from the end of the small Large Intestine intestine to the anus. (NCI)

C12420 LARYNX Larynx The cartilaginous structure of the respiratory tract Larynx between the pharynx and the trachea. It contains elastic vocal cords required for sound production. (NCI)

C32974 LEG Leg One of the two lower extremities in humans used for Leg locomotion and support. (NCI)

C52749 LEG SKIN Leg Skin The skin or integument surrounding the leg. (NCI) Leg Skin

C12743 LENS Crystalline Lens; A biconvex transparent structure of the eye through Lens Lens; Lens Of which light is focused on the retina. The lens sits Eye; Ocular Lens behind the iris and is supported by the zonule, which connects it to the ciliary body. The lens is an avascular structure. (NCI)

C32982 LESSER TROCHANTER A cone-shaped projection in the shaft of the femur in Lesser Trochanter which the iliopsoas muscle is attached. (NCI)

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 184 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C74456 - LOC - Anatomical Location Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C13046 LIGAMENT Ligament Band of fibrous tissue connecting bone to bone or Ligament cartilage to bone thereby supporting or strengthening a joint. (NCI)

C12429 LIMB Limb A body region referring to an upper or lower Limb extremity. (NCI)

C12742 LIMB, LOWER Lower Extremity The limb that is composed of the hip, thigh, leg and Lower Extremity foot. (NCI)

C12671 LIMB, UPPER Upper Extremity The region of the body that includes the arm, the Upper Extremity forearm, and hand. (NCI)

C12220 LIP Lip Fleshy fold which surrounds the opening of the mouth. Lip (NCI)

C12222 LIP, LOWER External Lower The external surface of the lower lip. (NCI) External Lower Lip Lip

C12221 LIP, UPPER External Upper The external surface of the upper lip. (NCI) External Upper Lip Lip

C12392 LIVER Liver A triangular-shaped organ located under the diaphragm Liver in the right hypochondrium. It is the largest internal organ of the body, weighting up to 2 kg. Metabolism and bile secretion are its main functions. It is composed of cells which have the ability to regenerate. (NCI)

C32996 LIVER FISSURE Liver Fissure A groove on the surface of the liver. Liver Fissure

C12744 LUMBAR VERTEBRA Lumbar Vertebra One of the five bones situated between the thoracic Lumbar Vertebra vertebrae and the sacrum in the lower part of the spine. (NCI)

C12786 LUNATE BONE Lunate Bone The bone in the proximal row of carpal bones that lies Lunate Bone between the scaphoid and triquetral bones. (NCI)

C12468 LUNG Lung One of a pair of viscera occupying the pulmonary Lung cavities of the thorax, the organs of respiration in which aeration of the blood takes place. As a rule, the right lung is slightly larger than the left and is divided into three lobes (an upper, a middle, and a lower or basal), while the left has two lobes (an upper and a lower or basal). Each lung is irregularly conical in shape, presenting a blunt upper extremity (the apex), a concave base following the curve of the diaphragm, an outer convex surface (costal surface), an inner or mediastinal surface (mediastinal surface), a thin and sharp anterior border, and a thick and rounded posterior border. (NCI)

C49282 LUNG, HILUM Hilar Area of the The wedge-shaped area at the central portion of the Hilar Area of the Lung Lung lung through which the bronchi, vessels and nerves enter or exit the organ. (NCI)

C32967 LUNG, LEFT Left Lung The 2-lobed lung located on the left side of the body. Left Lung (NCI)

C33020 LUNG, LEFT LOWER LOBE Lower Lobe of The larger lobe of the left lung, situated below and Lower Lobe of the Left Lung the Left Lung behind the oblique fissure. (NCI)

C33021 LUNG, LEFT UPPER LOBE Upper Lobe of The smaller lobe of the left lung, situated above and in Upper Lobe of the Left Lung the Left Lung front the oblique fissure, which includes the apex. (NCI)

C33483 LUNG, RIGHT Right Lung The 3-lobed lung located on the right side of the body. Right Lung (NCI)

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 185 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C74456 - LOC - Anatomical Location Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C33022 LUNG, RIGHT LOWER Lower Lobe of The lobe of the right lung situated below the oblique Lower Lobe of the Right Lung LOBE the Right Lung fissure. (NCI)

C12286 LUNG, RIGHT MIDDLE Middle Lobe of The smallest lobe of the right lung, situated above the Middle Lobe of the Right Lung LOBE the Right Lung oblique fissure and below the horizontal fissure. (NCI)

C33023 LUNG, RIGHT UPPER LOBE Upper Lobe of The lobe of the right lung, situated above the horizontal Upper Lobe of the Right Lung the Right Lung fissure, which includes the apex. (NCI)

C12745 LYMPH NODE Lymph Node A bean-shaped organ surrounded by a connective tissue Lymph Node capsule. It is part of the lymphatic system and is found through out the body. It is composed predominantly of lymphocytes and its main function is immune protection. (NCI)

C33031 LYMPH NODE HILUM Lymph Node The concave side of the lymph node. (NCI) Lymph Node Hilum Hilum

C32968 MAIN BRONCHUS, LEFT Left Main One of the two main bronchi. It is narrower but longer Left Main Bronchus Bronchus than the right main bronchus and connects to the left lung. (NCI)

C33486 MAIN BRONCHUS, RIGHT Right Main One of the two main bronchi. It is wider but shorter Right Main Bronchus Bronchus than the left main bronchus and connects to the right lung. (NCI)

C61599 MALE GENITALIA Male Genitalia Male internal and external organs of reproduction. Male Genitalia

C33051 MALLEUS Malleus A hammer-shaped bone, part of three interconnected Malleus small bones located in the middle ear. It is attached to the inner surface of the tympanic membrane and its function is to transmit sound vibrations. (NCI)

C12290 MANDIBLE Bone, The lower jaw bone holding the lower teeth. (NCI) Mandible Mandibular; Mandible; Inferior Maxillary Bone; Jaw

C12503 MASTOID PROCESS Mastoid Process A honeycombed section of bone located near the base Mastoid Process of the skull, protruding behind the outer ear. It is connected to the middle ear. (NCI)

C26470 MAXILLA Maxilla The upper jawbone in vertebrates: it is fused to the Maxilla cranium. (NCI)

C12275 MAXILLARY SINUS Maxillary Sinus A pyramidal-shaped, thin-walled, air-filled cavity Maxillary Sinus located in the maxilla. It is lined by mucus membrane and periosteum (mucoperiosteum) which contains cilia. It is adjacent to the nasal cavity and communicates with the middle meatus of the nose. It is the largest paranasal sinus and is composed of three recesses: alveolar, zygomatic, and infraorbital. (NCI)

C33073 MEDIASTINAL LYMPH Mediastinal A lymph node located in the mediastinum. Mediastinal Mediastinal Lymph Node NODE Lymph Node lymph nodes are arranged in three groups, one on the lateral, another on the medial, and a third on the anterior aspect of the vessels; the third group is, however, sometimes absent. (NCI)

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 186 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C74456 - LOC - Anatomical Location Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C12748 MEDIASTINUM Mediastinum A group of organs surrounded by loose connective Mediastinum tissue, separating the two pleural sacs, between the sternum anteriorly and the vertebral column posteriorly as well as from the thoracic inlet superiorly to the diaphragm inferiorly. The mediastinum contains the heart and pericardium, the bases of the great vessels, the trachea and bronchi, esophagus, thymus, lymph nodes, thoracic duct, phrenic and vagus nerves, and other structures and tissues. (NCI)

C32098 MEDIASTINUM, ANTERIOR Anterior The area between the lungs; it contains the thymus, Anterior Mediastinum Mediastinum some lymph nodes, and vessels and branches of the internal thoracic artery. (NCI)

C33123 MEDIASTINUM, MIDDLE Middle The broadest part of the lower portion of the Middle Mediastinum Mediastinum mediastinum. It contains the heart and the great vessels. (NCI)

C33368 MEDIASTINUM, Posterior The part of the lower portion of the mediastinum that Posterior Mediastinum POSTERIOR Mediastinum is located behind the pericardium. (NCI)

C33684 MEDIASTINUM, SUPERIOR Superior The part of the mediastinum that is located between the Superior Mediastinum Mediastinum upper part of the sternum in the front and the upper thoracic vertebrae in the back. (NCI)

C12442 MEDULLA OBLONGATA Medulla The lower portion of the brainstem located between Medulla Oblongata Oblongata the pons and brainstem. This structure contains several descending and ascending tracts, lower cranial nerve nuclei, a significant proportion of the reticular system of the brainstem and other structures. (NCI)

C12752 METATARSAL BONE Metatarsal Bone A bone belonging to the middle part of the foot located Metatarsal Bone between toes and ankle. There are 5 metatarsal bones and they are numbered from the medial side. (NCI)

C33108 METATARSOPHALANGEAL Metatarsophalan A spheroid joint located between the heads of the Metatarsophalangeal Joint JOINT geal Joint metatarsal bone and the base of the proximal phalanx of the toe. (NCI)

C12510 MIDBRAIN Mesencephalon; The uppermost portion of the brainstem located Mesencephalon Midbrain between the pons and the diencephalon. The midbrain contains the cerebral peduncles, oculomotor, trochlear and red nuclei, substantia nigra and various other nuclei and tracts. (NCI)

C12274 MIDDLE EAR Middle Ear The part of the ear including the eardrum and ossicles. Middle Ear The middle ear leads to the inner ear. (NCI)

C13166 MUCOSA Mucosa Mucous membrane. (NCI) Mucosa

C12435 MUSCLE TISSUE Muscle Tissue Tissue responsible for the body movements and the Muscle Tissue shape and size changes of interna organs. Muscle tissue is composed of specialized contractile cells. There are two types of muscle tissue recognized: striated and smooth muscle. The striated muscle tissue is further subdivided into skeletal, visceral striated, and cardiac muscle. (NCI)

C91405 MUSCLE TISSUE, DISTAL Distal Muscle A muscle located away from the trunk of the body. Distal Muscle (NCI)

C91404 MUSCLE TISSUE, Proximal Muscle A muscle located close to the trunk of the body. (NCI) Proximal Muscle PROXIMAL

C12314 MYOMETRIUM Myometrium The smooth muscle lining the uterus. (NCI) Myometrium

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 187 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C74456 - LOC - Anatomical Location Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C33156 NAIL Nail The cutaneous plate on the dorsal surface of the distal Nail end of a finger or toe. (NCI)

C33157 NASAL BONE Nasal Bone One of two small oblong bones placed side by side at Nasal Bone the middle and upper part of the face. (NCI)

C12424 NASAL CAVITY Nasal Cavity The proximal portion of the respiratory passages on Nasal Cavity either side of the nasal septum lying between the floor of the cranium and the roof of the mouth and extending from the face to the pharynx. The nasal cavity is lined with ciliated mucosa, extending from the nares to the pharynx. (NCI)

C33160 NASAL SEPTUM Nasal Septum The thin wall between the two nasal cavities. (NCI) Nasal Septum

C12423 NASOPHARYNX Nasopharynx The part of the pharynx in the back of the throat, at and Nasopharynx above the soft palate. The nasopharynx is continuous with the nasal passages. (NCI)

C33162 NAVICULAR BONE Navicular Bone An oval-shaped bone of the tarsus found on the medial Navicular Bone side of the foot. (NCI)

C13063 NECK Neck The region that connects the head to the rest of the Neck body. (NCI)

C12299 NIPPLE Nipple The pigmented protuberance on the surface of the Nipple breast through which milk is drawn from the breast. (NCI)

C12756 NOSE Nose A structure of special sense serving as an organ of the Nose sense of smell and as an entrance to the respiratory tract. (NCI)

C33178 NOSTRIL Nostril One of the two channels of the nose, from the point Nostril where they divide to the external opening. (NCI)

C12355 OCCIPITAL LOBE The posterior part of the cerebral hemisphere. (MeSH) Occipital Lobe

C33200 OLECRANON Olecranon A prominence at the proximal end of the ulna. It forms Olecranon the tip of the elbow. (NCI)

C28401 OLFACTORY BULB Olfactory Bulb Anatomical structure located in the vertebral forebrain Olfactory Bulb that receives neural input regarding odors that have been detected by cells within the nasal cavity. The axons of olfactory receptor cells extend into the olfactory bulb. (NCI)

C33205 OLFACTORY MUCOSA Olfactory The part of the nasal mucosa composed of Olfactory Mucosa Mucosa neuroepithelial tissue and mucus-producing Bowman's glands. The mucus moistens the epithelium and helps dissolve odor-containing gases. (NCI)

C12761 OPTIC NERVE Optic Nerve The second cranial nerve. (NCI) Optic Nerve

C12421 ORAL CAVITY Oral Cavity The cavity located at the upper end of the alimentary Oral Cavity canal, behind the teeth and gums that is bounded on the outside by the lips, above by the hard and soft palates and below by the tongue. (NCI)

C12347 ORBIT Eye Socket; The bony cavity of the skull which contains the eye, Orbit Ocular Orbit; anterior portion of the optic nerve, ocular muscles and Orbit; Orbital ocular adnexa. Seven bones contribute to the structure Cavity of the orbit: the frontal, maxillary, zygomatic, sphenoid, lacrimal, ethmoid, and palatine bones. (NCI)

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 188 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C74456 - LOC - Anatomical Location Codelist extensible: Yes

CDISC NCI CodeCDISC Submission Value SynonymCDISC DefinitionNCI Preferred Term

C12404 OVARYOvaryOne of the paired female reproductive glands Ovary containing the ova or germ cells; the ovary's stroma is a vascular connective tissue containing numbers of ovarian follicles enclosing the ova. (NCI)

C52745 PALATINE BONEPalatine BoneAn irregularly shaped bone positioned at the back part Palatine Bone of the nasal cavity between the maxilla and the pterygoid process of the sphenoid. It forms the posterior part of the hard palate and the lateral wall of the nasal fossa and helps to form the floor of the orbit as well as several adjoining parts. (NCI)

C12393 PANCREASPancreasAn organ behind the lower part of the stomach that is Pancreas the shape of a fish and about the size of a hand. It is a compound gland composed of both exocrine and endocrine tissues. The endocrine pancreas makes insulin so that the body can use glucose (sugar) for energy. The exocrine pancreas makes enzymes that help the body digest food. Spread all over the pancreas are areas called the Islets of Langerhans. The cells in these areas each have a special purpose. The alpha cells make glucagon, which raises the level of glucose in the blood; the beta cells make insulin; the delta cells make somatostatin. There are also PP cells and D1 cells, about which little is known. (NCI)

C12270PANCREAS, BODYBody of the The part of the pancreas from the point where it Body of the Pancreas Pancreas crosses the portal vein to the point where it enters the lienorenal ligament. (NCI)

C32509PANCREAS, ENDOCRINEEndocrine The pancreatic tissue that contains the islets of Endocrine Pancreas Pancreas Langerhans. It is responsible for the production and secretions of the pancreatic hormones. (NCI)

C32546PANCREAS, EXOCRINEExocrine An enzyme producing region of the pancreatic tissue Exocrine Pancreas Pancreas containing the pancreatic acini and exocrine intralobular ducts which collectively secrete the digestive enzymes into the main pancreatic duct to drain into the duodenal part of the small intestine. (NCI)

C12269 PANCREAS, HEADHead of the That portion of the pancreas lying in the concavity of Head of the Pancreas Pancreas the duodenum. (NCI)

C12271 PANCREAS, TAILTail of the The left extremity of the pancreas within the lienorenal Tail of the Pancreas Pancreas ligament. (NCI)

C12320 PARAMETRIUMParametriumThe subserous connective tissue of the pelvic floor of Parametrium the supracervical portion of the uterus. The parametrium extends laterally between the layers of the broad ligament. (NCI)

C12763 PARANASAL SINUSAccessory An air-filled cavity adjacent to the nasal cavity lined by Paranasal Sinus Sinuses; Nasal a mucous membrane and located in the bones of the Cavity; Nasal skull. There are four paranasal sinuses on each side of Sinuses; the face: ethmoid, frontal, maxillary, and sphenoid Paranasal Sinus sinus. (NCI)

C12765 PARATHYROID GLANDOne of two small paired endocrine glands, superior and Parathyroid Gland inferior, usually found embedded in the connective tissue capsule on the posterior surface of the thyroid gland; these glands secrete parathyroid hormone that regulates the metabolism of calcium and phosphorus. The parenchyma is composed of chief and oxyphilic cells arranged in anastomosing cords. (NCI)

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 189 of 431 -A> CDISC Controlled Terminology SDTM - 2012-03-23 C74456 - LOC - Anatomical Location Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C12354 PARIETAL LOBE Parietal Lobe One of the lobes of the cerebral hemisphere located Parietal Lobe superiorly to the occipital lobe and posteriorly to the frontal lobe. Cognition and visuospatial processing are its main function. (NCI)

C12427 PAROTID GLAND Parotid Gland The largest of the three paired salivary glands, located Parotid Gland in front of the ear. (NCI)

C33278 PAROTID GLAND LYMPH Parotid Gland A lymph node located close to, on, or within the Parotid Gland Lymph Node NODE Lymph Node parotid gland. (NCI)

C33282 PATELLA Patella A small flat triangular bone in front of the knee that Patella articulates with the femur and protects the knee joint. (NCI)

C33287 PELVIC BONE Pelvic Bone; The caudal portion of the trunk, bounded anteriorly and Pelvic Bone Pelvis laterally by the two hip bones incorporating the socket portion of the hip joint for each leg. Posteriorly it is bounded by the sacrum and coccyx. (NCI)

C12363 PELVIC LYMPH NODE Pelvic Lymph Any lymph node within the pelvic region. (NCI) Pelvic Lymph Node Node

C12767 PELVIS Pelvic Cavity; The bony, basin-shaped structure formed by the Pelvis Pelvis hipbones and the base of the backbone supporting the lower limbs in humans. (NCI)

C12409 PENIS Penis The male organ of urination and copulation. (NCI) Penis

C13005 PERICARDIUM Pericardium A conical membranous sac filled with serous fluid in Pericardium which the heart as well as the roots of the aorta and other large blood vessels are contained. (NCI)

C33301 PERINEUM Perineum The area located between the anus and vulva in females, Perineum and anus and scrotum in males. (NCI)

C12768 PERIPHERAL NERVE Peripheral Nerve Any nerve outside the brain or spinal cord that Peripheral Nerve connects with peripheral receptors or effectors. (NCI)

C12770 PERITONEUM Peritoneum The tissue that lines the wall of the abdominal cavity, Peritoneum intestine, and mesentery. It consists of the parietal peritoneum that covers the inside of the abdominal wall and the visceral peritoneum that covers the surface of the intestine and mesentery. (NCI)

C33318 PHARYNGEAL TONSIL Pharyngeal A fold of lymphatic tissue covered by ciliated Pharyngeal Tonsil Tonsil epithelium at the very back of the nose, in the roof of the nasopharynx. (NCI)

C12425 PHARYNX Pharynx A hollow tube that starts posterior to the mouth and Pharynx nasal cavity and ends superior to the trachea and esophagus. (NCI)

C12855 PISIFORM BONE Pisiform Bone The medial bone of the proximal row of carpal bones. Pisiform Bone (NCI)

C12399 PITUITARY GLAND Hypophysis Pea-sized endocrine gland located at the base of the Pituitary Gland Cerebri; brain in the pituitary fossa. It produces and secretes Hypophysis hormones such as oxytocin and vasopressin, to regulate the activities of the hypothalamus. (NCI)

C12840 PLEURAL CAVITY Pleural Cavity The cavity lined by the pleura, located in the thorax and Pleural Cavity contains heart and lungs. (NCI)

C33343 PORTAL VEIN Hepatic Portal A short thick trunk vein that transports blood Portal Vein Vein; Portal Vein containing the absorbed products of digestion from the intestine directly to the liver. (NCI)

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 190 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C74456 - LOC - Anatomical Location Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C12410 PROSTATE GLAND Prostate Gland The walnut shaped accessory sex gland of the male Prostate Gland reproductive system. It is located in the pelvis just below the bladder, surrounding the prostatic part of the urethra. The prostate gland secretes a fluid which is part of the semen. (NCI)

C13092 PROSTATE GLAND, Lateral Lobe of The prostate gland lobe that is located on the lateral Lateral Lobe of the Prostate LATERAL LOBE the Prostate side of the organ. (NCI)

C13094 PROSTATE GLAND, Middle Lobe of The upper, smaller part of the prostate between the Middle Lobe of the Prostate MIDDLE LOBE the Prostate ejaculatory ducts and the urethra. (NCI)

C13093 PROSTATE GLAND, Posterior Lobe The prostate gland lobe that is located on the posterior Posterior Lobe of the Prostate POSTERIOR LOBE of the Prostate side of the organ. (NCI)

C12452 PUTAMEN Putamen The largest and most lateral of the basal ganglia lying Putamen between the lateral medullary lamina of the globus pallidus and the external capsule. It is part of the neostriatum and forms part of the lentiform nucleus along with the globus pallidus. (MeSH)

C33433 PYLORIC SPHINCTER Pyloric The muscular structure at the distal portion of the Pyloric Sphincter Sphincter stomach, opening into the duodenum. (NCI)

C12838 RADIAL ARTERY Radial Artery The branch of the brachial artery that passes down the Radial Artery forearm. (NCI)

C12777 RADIUS Radius; Radius The long bone of the forearm that extends from the Radius Bone Bone lateral aspect of the elbow to the thumb-side of the wrist. (NCI)

C12390 RECTUM The terminal portion of the gastrointestinal tract, Rectum extending from the rectosigmoid junction to the anal canal. (NCI)

C49018 REGIONAL LYMPH NODE Regional Lymph A lymph node that drains lymph from a region of Regional Lymph Node Node interest. (NCI)

C12343 RETINA Retina A light-sensitive membrane that lines the back wall of Retina the eyeball. The retina is continuous with the optic nerve and this way transmits optical images to the brain. (NCI)

C12782 RIB Rib Any one of the paired bones, 12 on either side, Rib extending from the thoracic vertebrae toward the median line on the ventral aspect of the trunk. The long curved bones which form the rib cage. Generally, ribs 1 to 7 are connected to the sternum' by their costal cartilages and are called true ribs, whereas ribs 8 to 12 are termed false ribs. (NCI)

C52770 RIB 1 Rib 1 The first rib counting from the top of the rib cage Rib 1 down. (NCI)

C52769 RIB 10 Rib 10 The tenth rib counting from the top of the rib cage Rib 10 down. (NCI)

C52768 RIB 11 Rib 11 The eleventh rib counting from the top of the rib cage Rib 11 down. (NCI)

C52767 RIB 12 Rib 12 The twelfth rib counting from the top of the rib cage Rib 12 down. (NCI)

C52766 RIB 2 Rib 2 The second rib counting from the top of the rib cage Rib 2 down. (NCI)

C52765 RIB 3 Rib 3 The third rib counting from the top of the rib cage Rib 3 down. (NCI)

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 191 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C74456 - LOC - Anatomical Location Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C52764 RIB 4 Rib 4 The fourth rib counting from the top of the rib cage Rib 4 down. (NCI)

C52763 RIB 5 Rib 5 The fifth rib counting from the top of the rib cage Rib 5 down. (NCI)

C52762 RIB 6 Rib 6 The sixth rib counting from the top of the rib cage Rib 6 down. (NCI)

C52761 RIB 7 Rib 7 The seventh rib counting from the top of the rib cage Rib 7 down. (NCI)

C52760 RIB 8 Rib 8 The eighth rib counting from the top of the rib cage Rib 8 down. (NCI)

C52759 RIB 9 Rib 9 The ninth rib counting from the top of the rib cage Rib 9 down. (NCI)

C12853 SACRAL VERTEBRA Sacral Vertebra One of the usually five fused vertebrae forming the Sacral Vertebra triangular bone just below the lumbar vertebrae. (NCI)

C33507 SACROILIAC JOINT Sacroiliac Joint The joint located between the sacrum and the ilium. Sacroiliac Joint (NCI)

C33508 SACRUM Sacrum The triangular bone, made up of 5 fused bones of the Sacrum spine, located in the lower area of the spine between the fifth lumbar vertebra and the coccyx. (NCI)

C12854 SCAPHOID BONE Scaphoid Bone A nut-shaped bone of the wrist located in the radial site Scaphoid Bone of the hand. It is one of the eight carpal bones. (NCI)

C12783 SCAPULA Scapula; The flat triangle-shaped bone that connects the Scapula Shoulder Blade humerus with the clavicle in the back of the shoulder. (NCI)

C52810 SCIATIC NERVE Sciatic Nerve The longest single nerve that is formed by the merging Sciatic Nerve of the ventral rami of the L4, L5, and S1 in the pelvis and passes down the lower limb where it divides into the common peroneal and tibial nerves. (NCI)

C12784 SCLERA The white, opaque, fibrous, outer tunic of the eyeball, Sclera covering it entirely excepting the segment covered anteriorly by the cornea. It is essentially avascular but contains apertures for vessels, lymphatics, and nerves. It receives the tendons of insertion of the extraocular muscles and at the corneoscleral junction contains the canal of Schlemm. (From Cline et al., Dictionary of Visual Science, 4th ed)

C12785 SCROTUM Scrotum The musculocutaneous pouch that encloses the Scrotum testicles. (NCI)

C12787 SEMINAL VESICLE Seminal Sacs One of the two paired glands in the male genitourinary Seminal Vesicle system, posterior to the bladder and superior to the prostate gland, that produces fructose-rich seminal fluid which is a component of semen. These glands join the ipsilateral ductus deferens to form the ejaculatory duct. (NCI)

C25203 SHOULDER Shoulder The region of the body between the neck and the upper Shoulder arm. (NCI)

C33548 SHOULDER JOINT Shoulder Joint A ball-and-socket joint at the upper end of the Shoulder Joint humerus, located at the junction of humerus and scapula. (NCI)

C33556 SINUS Sinus A recess, cavity, or channel. (NCI) Sinus

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 192 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C74456 - LOC - Anatomical Location Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C13050 SKELETAL MUSCLE Skeletal Muscle Striated muscles that are under voluntary control of the Skeletal Muscle Tissue TISSUE Tissue organism. They are connected at either or both ends to a bone and are utilized for locomotion and other movements. (NCI)

C12470 SKIN Integument; Skin An organ that constitutes the external surface of the Skin body. It consists of the epidermis, dermis, and skin appendages. (NCI)

C12295 SKIN OF THE TRUNK Skin of the Trunk The skin or integument surrounding the trunk of the Skin of the Trunk body. (NCI)

C12789 SKULL Bone, Cranial; The bones that form the head, made up of the bones of Skull Cranium; Skull the braincase and face. (NCI)

C12386 SMALL INTESTINE Small Intestine The section of the intestines between the pylorus and Small Intestine cecum. The small intestine is approximately 20 feet long and consists of the duodenum, the jejunum, and the ileum. Its main function is to absorb nutrients from food as the food is transported to the large intestine. (NCI)

C12437 SMOOTH MUSCLE TISSUE Involuntary muscle tissue of the internal organs. It is Smooth Muscle Tissue composed of elongated muscle cells or fibers that are not arranged in a striated pattern and form layers of muscle tissue. The smooth muscle cells contain a contractile apparatus composed of thin and thick filaments and a cytoskeleton composed of intermediate filaments. (NCI)

C12231 SOFT PALATE A movable fold suspended from the posterior border Soft Palate of the hard palate. (MeSH)

C12471 SOFT TISSUE Soft Tissue Refers to muscle, fat, fibrous tissue, blood vessels or Soft Tissue other supporting tissue of the body.

C12432 SPLEEN Spleen An organ that is part of the hematopoietic and immune Spleen systems. It is composed of the white pulp and the red pulp and is surrounded by a capsule. It is located in the left hypochondriac region. Its functions include lymphocyte production, blood cell storage, and blood cell destruction. (NCI)

C33601 SPLEEN, HILUM Splenic Hilum The area of the spleen through which the vessels and Splenic Hilum nerves enter or exit the organ. (NCI)

C52730 STERNAL MANUBRIUM Sternal The upper segment of the sternum, quadrangular in Sternal Manubrium Manubrium shape, as well as wider superiorly and narrower inferiorly. The sternal manubrium articulates with the clavicle and first two ribs. (NCI)

C33615 STERNOCLAVICULAR Sternoclavicular The synovial juncture between the medial end of the Sternoclavicular Joint JOINT Joint clavicle and the anterior segment of the sternum. (NCI)

C12793 STERNUM Sterna; Sternum The long, flat bone connecting with the cartilages of Sternum the first seven ribs and the clavicle. (NCI)

C12391 STOMACH Stomach An organ located under the diaphragm, between the Stomach liver and the spleen as well as between the esophagus and the small intestine. The stomach is the primary organ of food digestion. (NCI)

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 193 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C74456 - LOC - Anatomical Location Codelist extensible: Yes

CDISC NCI CodeCDISC Submission Value SynonymCDISC DefinitionNCI Preferred Term

C12436 STRIATED MUSCLE TISSUEStriated muscles are appendicular and axial muscles Striated Muscle Tissue typically connected at either or both ends to the bony skeleton of the body. Striated muscle fibers contain a highly organized, contractile cytoskeletal apparatus with a striated microscopic appearance; muscle contraction is typically under voluntary control. (NCI)

C12280 SUBGLOTTISSubglottisThe area of the larynx below the vocal cords down to Subglottis the trachea. (NCI)

C12453 SUBSTANTIA NIGRASubstantia NigraA large cell mass extending forward, over the dorsal Substantia Nigra surface of the crus cerebri, from the rostral border of the pons into the subthalamic region. It is composed of a dorsal stratum of closely spaced pigmented cells, the pars compacta, and a larger ventral region of widely scattered cells, the pars reticulata. The pars compacta includes numerous cells that project forward to the striatum (caudate nucleus and putamen) and contain dopamine, which acts as the primary neurotransmitter at the synaptic endings. Other, apparently non-dopaminergic cells project to portions of the ventral nucleus of thalamus, the superior colliculus and reticular formation. The nigrostriatal projection is reciprocated by a striatonigral fiber system with multiple neurotransmitters, chief among which is gamma-aminobutyric acid (GABA). The substantia nigra is involved in the metabolic disturbances associated with Parkinson's disease and Huntington's disease. (NCI)

C12903SUPRACLAVICULAR Supraclavicular A lymph node which is located above the clavicle. Supraclavicular Lymph Node LYMPH NODE Lymph Node (NCI)

C33718 SYNOVIAL FLUIDSynovial Fluid; A viscid fluid secreted by the synovial membrane, Synovial Fluid Synovia serving as a lubricant. (NCI)

C33720 T1 VERTEBRAT1 VertebraThe first thoracic vertebra counting from the top down. T1 Vertebra (NCI)

C33721 T10 VERTEBRAT10 VertebraThe tenth thoracic vertebra counting from the top T10 Vertebra down. (NCI)

C33722 T11 VERTEBRAT11 VertebraThe eleventh thoracic vertebra counting from the top T11 Vertebra down. (NCI)

C33723 T12 VERTEBRAT12 VertebraThe twelfth thoracic vertebra counting from the top T12 Vertebra down. (NCI)

C33724 T2 VERTEBRAT2 VertebraThe second thoracic vertebra counting from the top T2 Vertebra down. (NCI)

C33725 T3 VERTEBRAT3 VertebraThe third thoracic vertebra counting from the top T3 Vertebra down. (NCI)

C33726 T4 VERTEBRAT4 VertebraThe fourth thoracic vertebra counting from the top T4 Vertebra down. (NCI)

C33727 T5 VERTEBRAT5 VertebraThe fifth thoracic vertebra counting from the top down. T5 Vertebra (NCI)

C33728 T6 VERTEBRAT6 VertebraThe sixth thoracic vertebra counting from the top T6 Vertebra down. (NCI)

C33729 T7 VERTEBRAT7 VertebraThe seventh thoracic vertebra counting from the top T7 Vertebra down. (NCI)

C33730 T8 VERTEBRAT8 VertebraThe eighth thoracic vertebra counting from the top down. (NCI)

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 194 of 431 -A> CDISC Controlled Terminology SDTM - 2012-03-23 C74456 - LOC - Anatomical Location Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C33731 T9 VERTEBRA T9 Vertebra The ninth thoracic vertebra counting from the top T9 Vertebra down. (NCI)

C52799 TALUS Talus The bone of the foot that connects with the tibia and Talus fibula to form the ankle joint. (NCI)

C12796 TARSUS BONE Bone, Tarsal; Any one of the seven bones forming the instep of the Tarsal Bone Tarsus Bone; foot. (NCI) Tarsus

C12797 TEMPORAL BONE Temporal Bone A large irregular bone situated at the base and side of Temporal Bone the skull, connected with the mandible via the temporomandibular joint. The temporal bone consists of the squamous, tympanic and petrous parts. The petrous portion of the temporal bone contains the vestibulocochlear organ of the inner ear. (NCI)

C12353 TEMPORAL LOBE Lower lateral part of the cerebral hemisphere. Temporal Lobe (MSH2001)

C12412 TESTIS Testicle; Testis Either of the paired male reproductive glands that Testis produce the male germ cells and the male hormones. (NCI)

C12459 THALAMUS Thalamus An ovoid mass composed predominantly of gray Thalamus substance and associated laminae of white substance. The thalamus is divided into anterior, medial, and lateral parts. The function of the thalamus is to relay sensory impulses and cerebellar and basal ganglia projections to the cerebral cortex. The thalamus is positioned within the posterior part of the diencephalon forming most of each lateral wall of the third ventricle. (NCI)

C33763 THIGH Thigh A part of the lower limb, located between hip and knee. Thigh (NCI)

C12905 THORACIC CAVITY Thoracic Cavity The cavity in the vertebrate body enclosed by the ribs Thoracic Cavity between the diaphragm and the neck and containing the lungs and heart. (NCI)

C12798 THORACIC VERTEBRA Thoracic One of 12 vertebrae in the human vertebral column. Thoracic Vertebra Vertebra The thoracic vertebrae are situated between the seventh cervical vertebra down to the first lumbar vertebra. (NCI)

C12799 THORAX Thorax The division of the body lying between the neck and Thorax the abdomen. (NCI)

C54272 THROAT Throat The narrow passage from the mouth to the cavity at the Throat back of the mouth. (NCI)

C12433 THYMUS GLAND Thymus Gland A bi-lobed organ surrounded by a connective tissue Thymus Gland capsule. It is located in the upper anterior portion of the chest, behind the sternum. It is composed predominantly of lymphocytes and fewer epithelial cells. Connective tissue septa separate the lobes into lobules. The lobules contain an outer portion (cortical zone) which is rich in lymphocytes and an inner portion (medullary zone) which is rich in epithelial cells. It is an organ essential for the development of the immune system. Its function is the maturation of the progenitor lymphoid cells to thymocytes and subsequently to mature T-cells. It reaches its greatest weight at puberty and subsequently begins to involute. (NCI)

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 195 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C74456 - LOC - Anatomical Location Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C12400 THYROID GLAND Thyroid Gland An endocrine gland located at the base of the neck that Thyroid Gland produces and secretes thyroxine and other hormones. Thyroxine is important for metabolic control. (NCI)

C32887 THYROID GLAND ISTHMUS The narrow, central portion of the thyroid gland that Thyroid Gland Isthmus crosses the trachea anteriorly and connects the two lobes of the gland. (NCI)

C32973 THYROID GLAND, LEFT Left Thyroid The cone-like lobe of the thyroid gland that is located Left Thyroid Gland Lobe LOBE Gland Lobe in the left side of the trachea. (NCI)

C33491 THYROID GLAND, RIGHT Right Thyroid The cone-like lobe of the thyroid gland that is located Right Thyroid Gland Lobe LOBE Gland Lobe in the right side of the trachea. (NCI)

C12800 TIBIA Tibia A bone located between the femur and the tarsus, being Tibia part of the lower leg. (NCI)

C33788 TOE Toe One of the terminal digits of the foot. (NCI) Toe

C33790 TOENAIL Toenail A thin, horny translucent plate covering the end of each Toenail toe. (NCI)

C12422 TONGUE Tongue The muscular organ located in the floor of the mouth Tongue and serving as the principal organ of taste and modification of the voice in speech. (NCI)

C12802 TONSIL Tonsil The two organs situated in the throat on either side of Tonsil the narrow passage from the mouth to the pharynx. They are composed of lymphoid tissues. (NCI)

C66864 TOOTH CANAL Tooth Canal The anatomic space in the root of a tooth that contains Tooth Canal nerves, blood vessels, and connective tissue. (NCI)

C12428 TRACHEA Trachea; The fibrocartilaginous, mucous-lined tube passing Trachea Windpipe from the larynx to the bronchi. (NCI)

C12857 TRAPEZIAL BONE Trapezial Bone A carpal bone on the thumb side of the hand that Trapezial Bone articulates with the 1st and 2nd metacarpals. (NCI)

C33809 TRAPEZIUS MUSCLE Trapezius One of a pair of flat, large, triangular muscles that Trapezius Muscle Muscle extend from the external occipital protuberance and the medial third of the superior nuchal line of the occipital bone to the middle of the back. The trapezius muscle is involved in moving the shoulder and arm. (NCI)

C12859 TRAPEZOID BONE Trapezoid Bone A carpal bone located between the trapezium and Trapezoid Bone capitate bones. (NCI)

C12858 TRIANGULAR BONE Triangular Bone A carpal bone located between the lunate and pisiform Triangular Bone bones. (NCI)

C33814 TROCHANTER Trochanter A bony protrusion on the femoral bone to which Trochanter muscles are attached. (NCI)

C12808 TROCHLEAR NERVE Trochlear Nerve The cranial nerve that controls the superior oblique Trochlear Nerve muscle of the eye. (NCI)

C33816 TRUNK Trunk The body excluding the head and neck and limbs. (NCI) Trunk

C33820 TUNICA INTIMA Tunica Intima The inner most layer of the blood vessel wall. The Tunica Intima consistency of the intima will vary depending on the type of blood vessel, but will always have an endothelial layer with a basal lamina. It may contain collagen and elastic fibers. (NCI)

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 196 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C74456 - LOC - Anatomical Location Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C12502 TYMPANIC MEMBRANE Tympanic A thin membrane that separates the external auditory Tympanic Membrane Membrane canal from the middle ear. The movement of the tympanic membrane in response to air pressure changes in the external ear facilitates the transmission of sound energy by causing vibration of the ossicular chain. (NCI)

C12809 ULNA Ulna Bone One of the bones that comprise the forearm. The Ulna largest aspect articulates with the humerus at the elbow joint and the smallest portion of the ulna articulates with the carpal bones in the wrist. (NCI)

C62432 UNCINATE PROCESS OF Uncinate A portion of the pancreas that extends behind the Uncinate Process of Pancreas PANCREAS Process of superior mesenteric artery and superior mesenteric Pancreas vein. (NCI)

C12416 URETER Ureter The thick-walled tube that carries urine from each Ureter kidney to the bladder. (NCI)

C12417 URETHRA Urethra The tube carrying urine from the bladder to outside of Urethra the body. (NCI)

C61125 URETHRA, ANTERIOR Anterior Portion The portion of the urethra that extends from the Anterior Portion of the Urethra of the Urethra meatus to the membranous urethra. (NCI)

C61123 URETHRA, PENILE Penile Portion of The portion of the urethra that spans the corpus Penile Portion of the Urethra the Urethra spongiosum. (NCI)

C61126 URETHRA, POSTERIOR Posterior The portion of the urethra that is located on the Posterior Portion of the Urethra Portion of the posterior aspect of the urogenital diaphragm. (NCI) Urethra

C13101 URETHRA, PROSTATIC Prostatic Urethra That part of the male urethra that passes through the Prostatic Urethra prostate gland. (NCI)

C12413 URINARY SYSTEM Urinary System The organs involved in the creation and excretion of Urinary System urine. (NCI)

C12405 UTERUS Uterus; Womb A hollow, thick-walled, muscular organ located within Uterus the pelvic cavity of a woman. Within the uterus the fertilized egg implants and the fetus develops during pregnancy. (NCI)

C12811 UVEA Uvea The pigmented layer of the eyeball between the tough, Uvea white outer coat of the eye and the retina. (NCI)

C12407 VAGINA Vagina The female genital canal, extending from the uterus to Vagina the vulva. (NCI)

C12813 VAS DEFERENS Duct carrying spermatozoa. (NCI) Vas Deferens

C12814 VEIN Vein A blood vessel that carries blood towards the heart. Vein

C12817 VENA CAVA Vena Cava A large vein which returns blood from the head, neck Vena Cava and extremities to the heart. (NCI)

C12998 VERTEBRAL COLUMN Vertebral A series of bones, muscles, tendons, and other tissues Vertebral Column Column reaching from the base of the skull to the tailbone. The vertebral column forms the axis of the skeleton and encloses as well as protects the spinal cord and the fluid surrounding the spinal cord. (NCI)

C12822 VOCAL CORD Vocal Cord A pair of small bands of muscle that stretch from the Vocal Cord thyroid cartilage in front to the arytenoid cartilage in back of the larynx. The vocal cords help prevent food entering the lungs and produce sound through vibration. (NCI)

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 197 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C74456 - LOC - Anatomical Location Codelist extensible: Yes

CDISC NCI CodeCDISC Submission Value SynonymCDISC DefinitionNCI Preferred Term

C33888 VOMERVomerA thin, paired or unpaired, trapezoidal bone of the skull Vomer located in the floor of the nasal cavity. The vomer forms the posterior and inferior parts of the nasal septum. (NCI)

C12408 VULVAExternal The external, visible part of the female genitalia Vulva Genitalia; Vulva surrounding the urethral and vaginal opening. The vulva includes the clitoris and inner as well as outer labia. (NCI)

C64192 WAISTWaistThe abdominal circumference at the navel. (NCI)Waist

C33894 WRIST JOINTWrist JointA joint between the distal end of the radius and the Wrist Joint proximal row of carpal bones. (NCI)

C33895

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 198 of 431 -A> CDISC Controlled Terminology SDTM - 2012-03-23 C76348 - MARISTAT - Marital Status Codelist extensible: Yes

CDISC NCI CodeCDISC Submission Value SynonymCDISC DefinitionNCI Preferred Term

C76240 ANNULLEDMarriage contract has been declared null and to not Annulled have existed. (HL7)

C51776 DIVORCEDMarriage contract has been declared dissolved and Divorced inactive. (HL7)

C53262 DOMESTIC PARTNERDomestic Person declares that a domestic partnership Domestic Partnership Partner relationship exists. (HL7)

C76241 INTERLOCUTORYTemporary order issued during the course of litigation. Interlocutory Marital Status (HL7)

C51777 LEGALLY SEPARATEDA person living apart from his/her spouse by legal Separated arrangement. (HL7)

C51773 MARRIEDA current marriage contract is active. (HL7)Married

C51774 NEVER MARRIEDNo marriage contract has ever been entered. (HL7)Never Married

C76242 POLYGAMOUSMore than 1 current spouse. (HL7)Polygamous

C51775

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 199 of 431 -A> CDISC Controlled Terminology SDTM - 2012-03-23 C96777 - MEDEVAL - Medical Evaluator Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C96561 ADJUDICATOR An individual that presides over and arbitrates between Adjudicator individuals or organizations.

C17721 NEUROLOGIST A physician who specializes in diagnosing and treating Neurologist diseases and disorders of the nervous system.

C96692 NEUROLOGIST 1 A neurologist performing the assessment that is given Neurologist 1 the designation of one.

C96606 NEUROLOGIST 2 A neurologist performing the assessment that is given Neurologist 2 the designation of two.

C17821 ONCOLOGIST A physician who specializes in diagnosing and treating Oncologist cancer. (NCI)

C96611 ONCOLOGIST 1 An oncologist performing the assessment that is given Oncologist 1 the designation of one.

C96612 ONCOLOGIST 2 An oncologist performing the assessment that is given Oncologist 2 the designation of two.

C17824 RADIOLOGIST A physician who specializes in the diagnostic and/or Radiologist therapeutic uses of radiation. (NCI)

C94530 RADIOLOGIST 1 A radiologist performing the assessment that is given Radiologist 1 the designation of one.

C94531 RADIOLOGIST 2 A radiologist performing the assessment that is given Radiologist 2 the designation of two.

C28747 READER An individual who takes non-quantifiable data and Reader provides quantifiable assessments for that data.

C94532 READER 1 A reader performing the assessment that is given the Reader 1 designation of one.

C94533 READER 2 A reader performing the assessment that is given the Reader 2 designation of two.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 200 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C85492 - METHOD - Method Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C23015 ACID FAST STAIN A microscopy staining method used to examine a Acid Fast Bacillae Staining Method specimen for the presence of acid-fast microorganisms, specifically mycobacteria.

C85554 ACRIDINE ORANGE STAIN A microscopy staining method that utilizes acridine Acridine Orange Staining Method orange, a fluorescent cationic dye that is selective for nucleic acids, to determine the presence of viable cells or microorganisms in a sample. Acridine orange interacts with RNA and DNA and the lysosomal compartment of cells.

C85555 AGAR DILUTION A method to determine microbial susceptibility to Agar Dilution Method antibiotics in which test bacteria is inoculated onto agar plates with serial dilutions of know quantities of antibiotics. The minimum inhibitory concentration of antibiotic is assessed.

C92304 ALCIAN BLUE AND A microscopy staining method that utilizes periodic Alcian Blue and Periodic Acid Schiff PERIODIC ACID SCHIFF acid, an oxoacid of iodine, Schiff reagent, the reaction Staining Method STAIN product of fuchsine and sodium bisulfite, and Alcian blue, a water soluble copper phthalocyanine dye. This staining method is used to differentially stain glycoproteins.

C92299 ALCIAN BLUE STAIN A microscopy staining method that utilizes alcian blue, Alcian Blue Staining Method a cationic, water soluble copper-containing phthalocyanine dye to determine the presence of acid mucopolysaccharides and glycosaminoglycans.

C16805 ANGIOGRAM An X-ray representation of blood vessels made after Lymphangiogram the injection of a radiopaque substance.

C85557 ANTIBIOTIC AGAR SCREEN A method used to detect organisms that have Antibiotic Agar Screening Method resistance to a single concentration of antibiotics in an agar matrix.

C85558 ANTIMICROBIAL A method to determine the microbial susceptibility to Antimicrobial Combination Testing COMBINATION TESTING two or more antibiotics. Numerical result translated Method into indifference, antagonism, synergism, or additive.

C85574 ATOMIC ABSORPTION A spectrometric method that determines the type and Atomic Absorption Spectroscopy SPECTROMETRY concentration of metal elements in a sample, based upon the principle that each elemental metal absorbs a particular wavelength of ultraviolet light when exposed to heat.

C38036 AUDIOMETRY Testing conducted utilizing a manual or Audiometric Test microprocessor audiometer to test for hearing loss.

C85573 AUSCULTATION Listening with a device, such as a stethoscope, to Auscultation anatomical locations that produce audible sounds like the heart, lungs and abdomen.

C85576 BETA LACTAMASE A test that detects beta lactamase produced by Beta Lactamase Screening Method Staphylococcus species, Haemophilus species, Moraxella catarrhalis, and Neisseria gonorrhoeae.

C85577 CALCOFLUOR WHITE A microscopy staining method that utilizes calcofluor, Calcofluor White Staining Method STAIN a fluorescent dye that preferentially stains chitin and cellulose on the cell walls of fungi, parasites, and some cysts of the Pneumocystis genus.

C85578 CELLULOSE TAPE A microbiological technique for specimen collection Cellulose Tape Method and mounting for microscopic examination that utilizes a cellulose-based adhesive ribbon.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 201 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C85492 - METHOD - Method Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C16431 CHROMATOGRAPHY A technique for the separation of complex mixtures Chromatography that relies on the differential affinities of substances for a gas or liquid mobile medium and for a stationary adsorbing medium through which they pass.

C40960 CISH Chromogenic in A laboratory procedure that combines the Chromogenic in situ Hybridization Situ sequence-specific detection aspects of FISH with the Hybridization simple detection methods of immunohistochemistry. Briefly, sequence-specific probes are hybridized to cells fixed on slides and the sequestered probe is visualized by a peroxidase reaction. It has the advantage of being a less costly assay that does not require fluorescence microscopy with results that are stable over time.

C17204 CT SCAN Computed A series of detailed pictures of areas inside the body; Computed Tomography Tomography; CT the pictures are created by a computer linked to an x-ray machine.

C85837 DARK FIELD MICROSCOPY A microscopic technique in which the light that does Dark Field Microscopy not come into contact with the structure or details of interest is subtracted from the ocular image. This yields an image in which the structure or details are alight while the areas where the structures or details are absent are dark.

C85595 DISK DIFFUSION A method to determine microbial susceptibility to Disk Diffusion Method antibiotics in which filter paper disks containing known concentrations of antibiotics are placed on the agar surface that has been previously inoculated with the bacteria of interest. Microbial susceptibility is assessed by measuring the area around the disk that is free of microbial growth.

C48789 DXA SCAN A technique for scanning bone and measuring bone Dual X-ray Absorptiometry mineral density (BMD).

C17455 EIA Enzyme Any of several immunoassay methods that use an Enzyme Immunoassay Immunoassay enzyme covalently linked to an antigen or antibody as a label; the most common types are enzyme-linked immunosorbent assay (ELISA) and enzyme-multiplied immunoassay technique (EMIT).

C16536 ELECTROPHORESIS The motion of charged particles in a colloid under the Electrophoresis influence of an electric field; particles with a positive charge go to the cathode and negative to the anode.

C16553 ELISA Enzyme-linked An immunoassay for detecting and measuring antigens ELISA Immunosorbent or antibodies in a solution; the solution is run over a Assay surface to which immobilized antibodies specific to the substance have been attached, and if the substance is present, it will bind to the antibody layer, and its presence is verified and visualized with an application of antibodies that have been tagged in some way.

C16546 ENDOSCOPY An examination of the body using an endoscope. Endoscopic Procedure

C85596 EPSILOMETER A method to determine microbial susceptibility to Epsilometry antibiotics in which a plastic strip impregnated with the antibiotic of interest is placed on an agar plate that has been inoculated with bacteria. The antibiotic diffuses from the strip producing a concentration gradient of drug on the agar. The point at which the elliptical shaped area of growth inhibition meets the strip is the minimum inhibitory concentration of the drug of interest.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 202 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C85492 - METHOD - Method Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C17563 FISH Fluorescence in A physical mapping approach that uses fluorescent tags Fluorescence in situ Hybridization Situ to detect hybridization of probes within metaphase Hybridization chromosomes or less condensed somatic interphase chromatin. This technique can be used for identification of chromosomal abnormalities and for gene mapping.

C17370 FLUORESCENT A bioassay in which fluorescent-coupled antibodies or Fluorescent Antibody Procedure IMMUNOASSAY antigens are used to quantify or qualify a biological response to a stimulus.

C16856 FLUORESCENT Microscopy of specimens stained with fluorescent dye Fluorescence Microscopy MICROSCOPY (usually fluorescein isothiocyanate) or of naturally fluorescent materials, which emit light when exposed to ultraviolet or blue light.

C85598 GIEMSA STAIN A microscopy staining method that utilizes Giemsa, a Giemsa Staining Method mixture of ethylene blue and eosin, which forms purplish-black crystals when dried. This stain preferentially binds to the phosphate groups of DNA and aggregates at areas with an increase in adenine-thymine binding, thus leading to chromosomal staining patterns that lend themselves to g-banding analysis. Additionally Giemsa can be used as a differential stain to determine microbial cell adherence to human cells as well as in the diagnosis of malaria, spirochete, and protozoal infections.

C85599 GRADIENT DIFFUSION A method to determine microbial susceptibility to Gradient Diffusion Method antibiotics in which an agar plate, which has a concentration gradient of the drug within the agar, is streaked with the microorganism of interest. Microbial susceptibility as well as minimum inhibitory concentration of antibiotic is assessed.

C23014 GRAM STAIN A microscopy staining method for staining and Gram Staining Method identifying bacteria, based on the differential retention of a crystal violet-iodine complex within the cell membrane. Gram-positive organisms will appear blue-black or purple while Gram-negative organisms will appear red.

C23011 HEMATOXYLIN AND H&E Stain A microscopy staining method that utilizes two Hematoxylin and Eosin Staining EOSIN STAIN separate dyes, one staining the nucleus and the other Method staining the cytoplasm and connective tissue. Hematoxylin is a dark purplish dye that stains the chromatin (nuclear material) within the nucleus. Eosin is an orangish-pink to red dye that stains the cytoplasmic material including connective tissue and collagen.

C85556 HIGH LEVEL A method to determine microbial susceptibility to high Aminoglycoside Screening Method AMINOGLYCOSIDE concentrations of aminoglycoside antibiotics. SCREEN

C16434 HPLC High Frequently referred to simply as HPLC, this form of High Performance Liquid Performance column chromatography is used frequently in Chromatography Liquid biochemistry. The analyte is forced through a column Chromatography by liquid at high pressure, which decreases the time the separated components remain on the stationary phase. Less time on the column then translates to narrower peaks in the resulting chromatogram and thence to better selectivity and sensitivity.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 203 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C85492 - METHOD - Method Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C18475 HPLC/MS High An analytical technique wherein high performance Liquid Chromatography Mass Performance liquid chromatography is coupled to mass Spectrometry Liquid spectrometry in order to separate, identify, and Chromatography/ quantify substances in a sample. Mass Spectrometry

C23020 IHC Immunohistoche Immunohistochemical staining techniques allow for Immunohistochemistry Staining mistry the visualization of antigens via the sequential Method application of a specific antibody to the antigen (primary antibody), a secondary antibody to the primary antibody and an enzyme complex with a chromogenic substrate. The enzymatic activation of the chromogen results in a visible reaction product at the antigen site. The specimen may then be counterstained and coverslipped. Results are interpreted using a light microscope and aid in the differential diagnosis of pathophysiological processes, which may or may not be associated with a particular antigen.

C85642 INDIA INK STAIN A microscopy staining method that utilizes India Ink, a India Ink Staining Method water soluble carbon-based black ink, to determine the presence of microorganisms that are surrounded by a gelatinous capsule. This is a negative staining method in which background is stained in black and the microbes and microscopic structures of interest remain white.

C85643 INFRARED A spectrometric method that determines the type and Infrared Spectrometry SPECTROMETRY concentration of elements or chemicals in a sample, based upon the principle that the atoms in a sample will vibrate or rotate at a specific frequency when exposed to infrared light.

C85649 IODINE STAIN A microscopy staining method that utilizes Iodine, an Iodine Staining Method element belonging to the halogen group, which specifically stains polysaccharides such as cellulose, chitin, glycogen, and starch a blue color.

C85650 IRON HEMATOXYLIN A microscopy staining method that utilizes a mixture Iron Hematoxylin Staining Method STAIN of iron and hematoxylin to visualize intracellular structures in a microscopic sample. In this dye system, iron acts as a mordant to hematoxylin rendering it insoluble, thereby allowing irreversible blue-black colored dyeing to the cell nucleus.

C85651 KINYOUN STAIN A microscopy acid fast staining method that utilizes Kinyoun Staining Method kinyoun carbol fuchsin, a dye containing basic fuchsin in solution with ethyl alcohol and aqueous phenol. This acid fast staining technique does not require heating during the primary staining step involving the carbol fuchsin.

C92301 LEAD CITRATE STAIN A microscopy staining method that utilizes lead Lead Citrate Staining Method citrate, a mixture of lead nitrate and sodium citrate, and has applications for electron microscopy staining.

C17995 LIGHT MICROSCOPY Light microscopy is a technique for producing visible Light Microscopy images of structures or details which are too small to be otherwise seen by the human eye. It involves passing light transmitted through or reflected from the subject through a series of lenses to be detected directly by the eye, imaged on a photographic plate, or captured digitally.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 204 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C85492 - METHOD - Method Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C92300 LUXOL FAST BLUE AND A microscopy staining method that utilizes luxol fast Luxol Fast Blue and Cresyl Violet CRESYL VIOLET STAIN blue, an alcohol soluble copper phthalocyanine dye, Staining Method and cresyl violet, an organic compound that is commonly used as a counter stain, to determine the presence of myelin as well as helicobacter and campylobacter bacterial species.

C85697 MACRO BROTH DILUTION A method to determine the minimum inhibitory Macro Broth Dilution Method concentration (MIC) of antibiotics in which growth media is pipetted into a test tube. Each tube contains a known concentration of drug and is inoculated with a known quantity of bacteria. The tubes are incubated for a specified period of time and each is assessed for bacterial cell growth. The drug concentration in the first tube showing no growth is known as the MIC for that antibiotic.

C16818 MAMMOGRAPHY A type of radiography used specifically to examine Mammography breast tissue. The procedure utilizes a low-dose of x-rays or radiation to generate an image.

C17156 MASS SPECTROMETRY An analytical technique wherein ions are separate Mass Spectrometry according to their ratio of charge to mass. From the mass spectrum produced, the atomic weight of the particle can be deduced.

C85701 MICRO BROTH DILUTION A method to determine the minimum inhibitory Micro Broth Dilution Method concentration (MIC) of antibiotics in which growth media is pipetted into a multi-well plate. Each well contains a known concentration of drug which is inoculated with a known quantity of bacteria. The plate is incubated for a specified period of time and each well is assessed for bacterial cell growth. The drug concentration in the first well showing no growth is known as the MIC for that antibiotic.

C85702 MICROBIAL Any technique in which a sample is condensed in order Microbial Concentration Method CONCENTRATION to afford greater sensitivity for the detection of microorganisms.

C85736 MODIFIED ACID FAST A microscopy staining method, that does not utilize Modified Acid Fast Staining Method STAIN heat in the slide preparation, used to examine a specimen for the presence of acid-fast microorganisms, specifically nocardia.

C16809 MRI Magnetic Imaging that uses radiofrequency waves and a strong Magnetic Resonance Imaging Resonance magnetic field rather than x-rays to provide amazingly Imaging clear and detailed pictures of internal organs and tissues. The technique is valuable for the diagnosis of many pathologic conditions, including cancer, heart and vascular disease, stroke, and joint and musculoskeletal disorders.

C25598 OBSERVATION Watching something and taking note of what happens. Observation

C85776 OPTICAL DENSITY A quantification of the amount of light that is absorbed Optical Density Measurement MEASUREMENT by or transmitted through a substance.

C16950 PALPATION A method of feeling with the hands during a physical Palpation examination. The health care provider touches and feels the patient's body to examine the size, consistency, texture, location and tenderness of an organ or body part.

C94528 PANENDOSCOPY An endoscopic examination of the pharynx, larynx, Panendoscopy trachea and esophagus.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 205 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C85492 - METHOD - Method Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C62298 PERCUSSION A diagnostic test performed on a tooth by tapping on Dental Percussion the crown with a dental instrument.

C23019 PERIODIC ACID SCHIFF A microscopy staining method that utilizes Schiff's Periodic Acid Schiff Staining STAIN reagent, a solution composed of pararosanilin treated Method with sulfurous acid, which selectively reacts with and stains aldehydes pink to determine the presence of glycogen, mucin, mucoprotein, glycoprotein, as well as fungi. Periodic Acid Schiff staining is useful for outlining tissue structures such as basement membranes, capsules and blood vessels.

C17007 PET/CT SCAN An imaging technique that utilizes positron emission Positron Emission Tomography tomography and computed tomography in a single machine.

C16857 PHASE CONTRAST A microscopic technique in which the amplitude shift Phase-Contrast Microscopy MICROSCOPY that occurs when light passes through a specimen highlights structures or details within the specimen.

C94527 PHOTOGRAPHY The process by which an image is acquired by Photography recording light emissions.

C17057 RIA Radioimmunoass Radioimmunoassay (RIA) is an immunological Radioimmunoassay ay technique, which quantitatively determines antigen and antibody concentrations, using a radioactively labeled substance (radioligand), either directly or indirectly.

C85801 RYAN BLUE STAIN A microscopy staining method that utilizes a modified Ryan Blue Staining Method trichrome stain to determine the presence of microspordial, sporulating species. This staining technique substitutes aniline blue for the fast green counterstain of the original trichrome staining method and decreased levels of phosphotungstic acid in the reagent.

C16855 SCANNING ELECTRON An electron microscopy imaging technique that is Scanning Electron Microscopy MICROSCOPY utilized to examine structural components of a sample by passing electrons through a specimen that has been coated with a heavy metal.

C62667 SCINTIGRAPHY An imaging technique that uses a small dose of a Radionuclide Imaging radioactive chemical (isotope) called a tracer that can detect sites of cancer growth, trauma, infection or degenerative disorders. The tracer, which is either injected into a vein or swallowed, travels through the bloodstream to the target organ, and emits gamma rays, which are detected by a gamma camera and analyzed by a computer to form an image of the target organ. (NCI)

C75583 SLIT LAMP Examination of the anterior segment of the eye using a Slit-lamp Examination medical instrument called a slit lamp.

C20645 SPIRAL CT Spiral Computed A method of examining body organs by scanning them Spiral CT Tomography with X rays and using a computer to construct a series of cross-sectional scans along a single axis.

C85819 THICK SMEAR A blood smear technique used to make a thick blood Thick Smear Technique smear on a microscope slide which is generally used to look for blood parasites such as those causing malaria.

C85820 THIN SMEAR A blood smear technique used to make a thin blood Thin Smear Technique smear on a microscope slide which is generally used to look for blood parasites such as those causing malaria.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 206 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C85492 - METHOD - Method Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C92302 TOLUIDINE BLUE STAIN A microscopy staining method that utilizes toluidine Toluidine Blue Staining Method blue, a solution composed of tolonium chloride, to determine the presence of mast cells, lignin, proteoglycans and glycosaminoglycans.

C15350 TOTAL BODY IRRADIATION A therapeutic procedure that involves the irradiation of Total-Body Irradiation the whole body with ionizing or non-ionizing radiation. (NCI)

C96640 TOTAL BODY A diagnostic radiologic test that involves the Total Body Radiography RADIOGRAPHY examination of the entire body in a single procedure.

C18216 TRANSMISSION ELECTRON An electron microscopy imaging technique that is Transmission Electron Microscopy MICROSCOPY utilized to examine structural components of a sample by passing electrons through the specimen.

C23012 TRICHROME STAIN A microscopy staining method that utilizes two or Trichrome Staining Method more colored, acidic dyes of contrasting colors. Masson trichrome is a mixture of three dyes including aniline blue, Beibrich scarlet and Weigert's iron hematoxylin. Other related, modified trichrome staining methods include Lillie's trichrome, Gomori's trichrome and Mallory's trichrome.

C17230 ULTRASOUND A technique in which high-frequency sound waves are Ultrasound Imaging bounced off internal organs and the echo pattern is converted into a 2 dimensional picture of the structures beneath the transducer.

C92303 URANYL ACETATE STAIN A microscopy staining method that utilizes uranyl Uranyl Acetate Staining Method acetate, a water insoluble yellow crystalline solid, which is used as a negative stain in electron microscopy.

C85828 WEBER GREEN STAIN A microscopy staining method that utilizes a modified Weber Green Staining Method trichrome stain to determine the presence of microspordial, sporulating species. The staining method utilizes chromotrope 2R, a red acidic dye, the counterstain fast green, and phosphotungstic acid.

C85829 WRIGHT STAIN A microscopy staining method that utilizes the Wright Staining Method Romanowsky stains, eosin and methylene blue, solubilized in methanol. In this staining protocol, methanol is also utilized as a fixative agent prior to staining.

C23041 WRIGHT-GIEMSA STAIN A microscopy staining method that is a combination of Wright-Giemsa Staining Method the Wright and Giemsa staining protocols and utilizes the Romanowsky stains, which are mixtures of eosin and thiazine dyes such as methylene blue. It produces darker blue and magenta shades than the giemsa stain alone, which may provide better contrast in microscopy.

C85830 X-RAY FLUORESCENCE A spectrometric method that determines the type and X-Ray Fluorescence Spectrometry SPECTROMETRY concentration of elements or chemicals in a sample, based upon the principle that each element emits fluorescent light of a particular wavelength when exposed to an X-ray.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 207 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C85492 - METHOD - Method Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C38101 XRAY Radiography A radiographic procedure using the emission of x-rays Radiography to form an image of the structure penetrated by the radiation.

C85831 ZIEHL NEELSEN ACID FAST A microscopy acid fast staining method that utilizes Ziehl Neelsen Acid Fast Staining STAIN Ziehl-Neelsen carbol fuchsin, acid alcohol and Method methylene blue, to determine the presence of acid fast microorganisms. This acid fast staining technique requires heating during the primary staining step involving the carbol fuchsin.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 208 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C85491 - MICROORG - Microorganism Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C86077 ABIOTROPHIA Any bacteria that is not assigned to the species level Abiotrophia but can be assigned to the Abiotrophia genus level.

C86078 ABIOTROPHIA DEFECTIVA Any bacterial organism that can be assigned to the Abiotrophia defectiva species Abiotrophia defectiva.

C86079 ACHROMOBACTER Any bacteria that is not assigned to the species level Achromobacter but can be assigned to the Achromobacter genus level.

C86080 ACHROMOBACTER ALCALIGENES Any bacterial organism that can be assigned to the Achromobacter denitrificans DENITRIFICANS DENITRIFICAN species Achromobacter denitrificans. S

C86081 ACHROMOBACTER Any bacterial organism that can be assigned to the Achromobacter piechaudii PIECHAUDII species Achromobacter piechaudii.

C86082 ACHROMOBACTER ALCALIGENES Any bacterial organism that can be assigned to the Achromobacter xylosoxidans XYLOSOXIDANS XYLOSOXIDAN species Achromobacter xylosoxidans. S

C86083 ACIDAMINOCOCCUS Any bacteria that is not assigned to the species level Acidaminococcus but can be assigned to the Acidaminococcus genus level.

C86084 ACIDAMINOCOCCUS Any bacterial organism that can be assigned to the Acidaminococcus fermentans FERMENTANS species Acidaminococcus fermentans.

C86085 ACIDOVORAX Any bacteria that is not assigned to the species level Acidovorax but can be assigned to the Acidovorax genus level.

C86086 ACIDOVORAX Any bacterial organism that can be assigned to the Acidovorax delafieldii DELAFIELDII species Acidovorax delafieldii.

C86087 ACIDOVORAX FACILIS Any bacterial organism that can be assigned to the Acidovorax facilis species Acidovorax facilis.

C86088 ACIDOVORAX TEMPERANS Any bacterial organism that can be assigned to the Acidovorax temperans species Acidovorax temperans.

C76200 ACINETOBACTER Any bacteria that is not assigned to the species level Acinetobacter but can be assigned to the Acinetobacter genus level.

C86089 ACINETOBACTER ACINETOBACT Any bacterial organism that can be assigned to the Acinetobacter anitratus ANITRATUS ER species Acinetobacter anitratus. BAUMANNII; ACINETOBACT ER CALCOACETIC US SUBSP. ANITRATUS

C86090 ACINETOBACTER Any bacterial organism that can be assigned to the Acinetobacter calcoaceticus CALCOACETICUS species Acinetobacter calcoaceticus.

C86091 ACINETOBACTER A non-taxonomic grouping of bacteria assigned to the Acinetobacter CALCOACETICUS-BAUMA Acinetobacter genus that include the A. calcoaceticus calcoaceticus/baumannii Complex NNII COMPLEX and A. baumannii species.

C86092 ACINETOBACTER Any bacterial organism that can be assigned to the Acinetobacter haemolyticus HAEMOLYTICUS species Acinetobacter haemolyticus.

C86093 ACINETOBACTER Any bacterial organism that can be assigned to the Acinetobacter johnsonii JOHNSONII species Acinetobacter johnsonii.

C86094 ACINETOBACTER JUNII Any bacterial organism that can be assigned to the Acinetobacter junii species Acinetobacter junii.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 209 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C85491 - MICROORG - Microorganism Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C86095 ACINETOBACTER LWOFFII ACINETOBACT Any bacterial organism that can be assigned to the Acinetobacter lwoffii ER species Acinetobacter lwoffii. CALCOACETIC US SUBSP. LWOFFII

C86096 ACINETOBACTER Any bacterial organism that can be assigned to the Acinetobacter radioresistens RADIORESISTENS species Acinetobacter radioresistens.

C86097 ACTINOBACILLUS Any bacteria that is not assigned to the species level Actinobacillus but can be assigned to the Actinobacillus genus level.

C86098 ACTINOBACILLUS CDC GROUP Any bacterial organism that can be assigned to the Actinobacillus ACTINOMYCETEMCOMITA HB-3 species Actinobacillus actinomycetemcomitans. actinomycetemcomitans NS

C86099 ACTINOBACILLUS EQUULI Any bacterial organism that can be assigned to the Actinobacillus equuli species Actinobacillus equuli.

C86100 ACTINOBACILLUS Any bacterial organism that can be assigned to the Actinobacillus ligniersii LIGNIERSII species Actinobacillus ligniersii.

C86101 ACTINOBACILLUS HAEMOPHILUS Any bacterial organism that can be assigned to the Actinobacillus pleuropneumoniae PLEUROPNEUMONIAE PLEUROPNEU species Actinobacillus pleuropneumoniae. MONIAE

C86102 ACTINOBACILLUS SUIS Any bacterial organism that can be assigned to the Actinobacillus suis species Actinobacillus suis.

C86103 ACTINOBACILLUS UREAE PASTEURELLA Any bacterial organism that can be assigned to the Actinobacillus ureae UREAE species Actinobacillus ureae.

C86104 ACTINOMADURA Any bacteria that is not assigned to the species level Actinomadura but can be assigned to the Actinomadura genus level.

C86105 ACTINOMADURA Any bacterial organism that can be assigned to the Actinomadura madurae MADURAE species Actinomadura madurae.

C86106 ACTINOMADURA Any bacterial organism that can be assigned to the Actinomadura pelletieri PELLETIERI species Actinomadura pelletieri.

C76201 ACTINOMYCES Any bacteria that is not assigned to the species level Actinomyces but can be assigned to the Actinomyces genus level.

C86107 ACTINOMYCES BOVIS PROACTINOMY Any bacterial organism that can be assigned to the Actinomyces bovis CES BOVIS; species Actinomyces bovis. SPHAEROTILU S BOVIS; CLADOTHRIX BOVIS; STREPTOTHRIX BOVIS; NOCARDIA BOVIS; ACTINOCLADO THRIX BOVIS; OOSPORA BOVIS; SARCOMYCES BOVIS; DISCOMYCES BOVIS

C86108 ACTINOMYCES ISRAELII Any bacterial organism that can be assigned to the Actinomyces israelii species Actinomyces israelii.

C86109 ACTINOMYCES MEYERII Any bacterial organism that can be assigned to the Actinomyces meyerii species Actinomyces meyerii.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 210 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C85491 - MICROORG - Microorganism Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C86110 ACTINOMYCES Any bacterial organism that can be assigned to the Actinomyces naseslundii NAESLUNDII species Actinomyces naseslundii.

C86111 ACTINOMYCES NEUII Any bacterial organism that can be assigned to the Actinomyces neuii species Actinomyces neuii.

C86112 ACTINOMYCES Any bacterial organism that can be assigned to the Actinomyces odontolyticus ODONTOLYTICUS species Actinomyces odontolyticus.

C86113 ACTINOMYCES RADINGAE Any bacterial organism that can be assigned to the Actinomyces radingae species Actinomyces radingae.

C86114 ACTINOMYCES Any bacterial organism that can be assigned to the Actinomyces turicensis TURICENSIS species Actinomyces turicensis.

C86115 ACTINOMYCES VISCOSUS Any bacterial organism that can be assigned to the Actinomyces viscosus species Actinomyces viscosus.

C86116 AEROBIC AEROBIC Any rod-shaped bacteria with an oxygen-based Aerobic Gram Negative Bacillus GRAM-NEGATIVE GRAM-NEGATI metabolism and has a cell wall that contains low levels BACILLUS VE ROD of peptidoglycan and stains pink with the Gram staining technique.

C86117 AEROBIC Any spherical-shaped bacteria with an oxygen-based Aerobic Gram Negative Coccus GRAM-NEGATIVE COCCUS metabolism and a cell wall that contains low levels of peptidoglycan and stains pink with the Gram staining technique.

C86118 AEROBIC GRAM-POSITIVE AEROBIC Any rod-shaped bacteria with an oxygen-based Aerobic Gram Positive Bacillus BACILLUS GRAM-POSITIV metabolism and has a peptidoglycan-rich cell wall that E ROD stains dark purple with the Gram staining technique.

C86119 AEROBIC GRAM-POSITIVE Any spherical-shaped bacteria with an oxygen-based Aerobic Gram Positive Coccus COCCUS metabolism and a peptidoglycan-rich cell wall that stains dark purple with the Gram staining technique.

C86120 AEROBIC Any bacteria assigned to the genus Streptococcus that Aerobic Streptococcus STREPTOCOCCUS requires oxygen to grow or respirate.

C86121 AEROCOCCUS GAFFKYA Any bacteria that is not assigned to the species level Aerococcus SPECIES but can be assigned to the Aerococcus genus level.

C86122 AEROCOCCUS URINAE Any bacterial organism that can be assigned to the Aerococcus urinae species Aerococcus urinae.

C86123 AEROCOCCUS VIRIDANS Any bacterial organism that can be assigned to the Aerococcus viridans species Aerococcus viridans.

C86124 AEROMONAS Any bacteria that is not assigned to the species level Aeromonas but can be assigned to the Aeromonas genus level.

C86125 AEROMONAS AEROMONAS Any bacterial organism that can be assigned to the Aeromonas hydrophila HYDROPHILA HYDROPHILA species Aeromonas hydrophila. GROUP

C86126 AEROMONAS JANDAEI Any bacterial organism that can be assigned to the Aeromonas jandaei species Aeromonas jandaei.

C86127 AEROMONAS PUNCTATA AEROMONAS Any bacterial organism that can be assigned to the Aeromonas punctata CAVIAE species Aeromonas punctata.

C86128 AEROMONAS Any bacterial organism that can be assigned to the Aeromonas salmonicida SALMONICIDA species Aeromonas salmonicida.

C86129 AEROMONAS SCHUBERTII Any bacterial organism that can be assigned to the Aeromonas schubertii species Aeromonas schubertii.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 211 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C85491 - MICROORG - Microorganism Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C86130 AEROMONAS SOBRIA Any bacterial organism that can be assigned to the Aeromonas sobria species Aeromonas sobria.

C86131 AEROMONAS VERONII Any bacterial organism that can be assigned to the Aeromonas veronii species Aeromonas veronii.

C86132 AGGREGATIBACTER Any bacteria that is not assigned to the species level Aggregatibacter but can be assigned to the Aggregatibacter genus level.

C86133 AGGREGATIBACTER HAEMOPHILUS Any bacterial organism that can be assigned to the Aggregatibacter ACTINOMYCETEMCOMITA ACTINOMYCET species Aggregatibacter actinomycetemcomitans. actinomycetemcomitans NS EMCOMITANS

C86134 AGGREGATIBACTER CDC GROUP Any bacterial organism that can be assigned to the Aggregatibacter aphrophilus APHROPHILUS HB-2; species Aggregatibacter aphrophilus. HAEMOPHILUS PARAPHROPHI LUS; BETA-LACTAM ASE NEGATIVE HAEMOPHILUS PARAPHROPHI LUS; HAEMOPHILUS APHROPHILUS

C86135 AGGREGATIBACTER HAEMOPHILUS Any bacterial organism that can be assigned to the Aggregatibacter segnis SEGNIS SEGNIS species Aggregatibacter segnis.

C86011 AGROBACTERIUM Any bacteria that is not assigned to the species level Agrobacterium but can be assigned to the Agrobacterium genus level.

C86137 AGROBACTERIUM Any bacterial organism that can be assigned to the Agrobacterium radiobacter RADIOBACTER species Agrobacterium radiobacter.

C86138 AGROBACTERIUM CDC GROUP Any bacterial organism that can be assigned to the Agrobacterium tumefaciens TUMEFACIENS VD-3; species Agrobacterium tumefaciens. RHIZOBIUM RADIOBACTER

C86012 ALCALIGENES Any bacteria that is not assigned to the species level Alcaligenes but can be assigned to the Alcaligenes genus level.

C86140 ALCALIGENES FAECALIS ALCALIGENES Any bacterial organism that can be assigned to the Alcaligenes faecalis ODORANS species Alcaligenes faecalis.

C86871 ALISTIPES PUTREDINIS BACTEROIDES Any bacterial organism that can be assigned to the Alistipes putredinis PUTREDINIS species Alistipes putredinis.

C86142 ANAEROBIC ANAEROBIC Any rod-shaped bacteria that does not require oxygen Anaerobic Gram Negative Bacillus GRAM-NEGATIVE GRAM-NEGATI to grow or respirate and has a cell wall that contains BACILLUS VE ROD low levels of peptidoglycan and stains pink with the Gram staining technique.

C86143 ANAEROBIC Any spherical-shaped bacteria that does not require Anaerobic Gram Negative Coccus GRAM-NEGATIVE COCCUS oxygen to grow or respirate and has a cell wall that contains low levels of peptidoglycan and stains pink with the Gram staining technique.

C86144 ANAEROBIC ANAEROBIC Any rod-shaped bacteria that does not require oxygen Anaerobic Gram Positive Bacillus GRAM-POSITIVE BACILLUS GRAM-POSITIV to grow or respirate and has a peptidoglycan-rich cell E ROD wall that stains dark purple with the Gram staining technique.

C86145 ANAEROBIC Any spherical-shaped bacteria that does not require Anaerobic Gram Positive Coccus GRAM-POSITIVE COCCUS oxygen to grow or respirate and has a peptidoglycan-rich cell wall that stains dark purple with the Gram staining technique.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 212 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C85491 - MICROORG - Microorganism Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C86146 ANAEROBIC Any bacteria assigned to the genus Streptococcus that Anaerobic Streptococcus STREPTOCOCCUS does not require oxygen to grow or respirate.

C86872 ANAEROCOCCUS Any bacteria that is not assigned to the species level Anaerococcus but can be assigned to the Anaerococcus genus level.

C86874 ANAEROCOCCUS PEPTOSTREPT Any bacterial organism that can be assigned to the Anaerococcus hydrogenalis HYDROGENALIS OCOCCUS species Anaerococcus hydrogenalis. HYDROGENALI S

C86875 ANAEROCOCCUS Any bacterial organism that can be assigned to the Anaerococcus prevotii PREVOTII species Anaerococcus prevotii.

C86876 ANAEROCOCCUS GAFFKYA Any bacterial organism that can be assigned to the Anaerococcus tetradius TETRADIUS ANAEROBIA; species Anaerococcus tetradius. PEPTOSTREPT OTOCCUS TETRADIUS

C86877 ANAEROCOCCUS Any bacterial organism that can be assigned to the Anaerococcus vaginalis VAGINALIS species Anaerococcus vaginalis.

C86147 ARCANOBACTERIUM Any bacteria that is not assigned to the species level Arcanobacterium but can be assigned to the Arcanobacterium genus level.

C86148 ARCANOBACTERIUM Any bacterial organism that can be assigned to the Arcanobacterium bernardiae BERNARDIAE species Arcanobacterium bernardiae.

C86149 ARCANOBACTERIUM CORYNEBACTE Any bacterial organism that can be assigned to the Arcanobacterium haemolyticum HAEMOLYTICUM RIUM species Arcanobacterium haemolyticum. HAEMOLYTICU M; CORYNEBACTE RIUM HAEMOLYTICU S

C86150 ARCANOBACTERIUM ACTINOMYCES Any bacterial organism that can be assigned to the Arcanobacterium pyogenes PYOGENES PYOGENES; species Arcanobacterium pyogenes. CORYNEBACTE RIUM PYOGENES

C86152 ARCOBACTER Any bacteria that is not assigned to the species level Arcobacter but can be assigned to the Arcobacter genus level.

C86153 ARCOBACTER BUTZLERI CAMPYLOBAC Any bacterial organism that can be assigned to the Arcobacter butzleri TER BUTZLERI species Arcobacter butzleri.

C86154 ARCOBACTER CAMPYLOBAC Any bacterial organism that can be assigned to the Arcobacter cryaerophilus CRYAEROPHILUS TER species Arcobacter cryaerophilus. CRYAEROPHIL US

C86155 ARTHROBACTER Any bacteria that is not assigned to the species level Arthrobacter but can be assigned to the Arthrobacter genus level.

C86156 ATOPOBIUM MINUTUM LACTOBACILL Any bacterial organism that can be assigned to the Atopobium minutum US MINUTIS; species Atopobium minutum. LACTOBACILL US MINUTUS

C86157 ATOPOBIUM PARVULUM STREPTOCOCC Any bacterial organism that can be assigned to the Atopobium parvulum US PARVULUS species Atopobium parvulum.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 213 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C85491 - MICROORG - Microorganism Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C86158 AVIBACTERIUM HAEMOPHILUS Any bacterial organism that can be assigned to the Avibacterium paragallinarum PARAGALLINARUM PARAGALLINA species Avibacterium paragallinarum. RUM

C76202 BACILLUS Any bacteria that is not assigned to the species level Bacillus but can be assigned to the Bacillus genus level.

C86159 BACILLUS ALVEI Any bacterial organism that can be assigned to the Bacillus alvei species Bacillus alvei.

C86160 BACILLUS ANTHRACIS Any bacterial organism that can be assigned to the Bacillus anthracis species Bacillus anthracis.

C86161 BACILLUS CEREUS Any bacterial organism that can be assigned to the Bacillus cereus species Bacillus cereus.

C86162 BACILLUS LENTUS Any bacterial organism that can be assigned to the Bacillus lentus species Bacillus lentus.

C86163 BACILLUS LICHENIFORMIS Any bacterial organism that can be assigned to the Bacillus licheniformis species Bacillus licheniformis.

C86164 BACILLUS MEGATERIUM Any bacterial organism that can be assigned to the Bacillus megaterium species Bacillus megaterium.

C86165 BACILLUS MYCOIDES Any bacterial organism that can be assigned to the Bacillus mycoides species Bacillus mycoides.

C86166 BACILLUS POLYMYXA Any bacterial organism that can be assigned to the Bacillus polymyxa species Bacillus polymyxa.

C86167 BACILLUS SUBTILIS Any bacterial organism that can be assigned to the Bacillus subtilis species Bacillus subtilis.

C14187 BACTERIA BACTERIUM; Any organism assigned to the kingdom Bacteria. Bacteria EUBACTERIA

C76204 BACTEROIDES Any bacteria that is not assigned to the species level Bacteroides but can be assigned to the Bacteroides genus level.

C86168 BACTEROIDES CACCAE BACTEROIDES Any bacterial organism that can be assigned to the Bacteroides caccae FRAGILIS species Bacteroides caccae. GROUP 3452A

C86169 BACTEROIDES Any bacterial organism that can be assigned to the Bacteroides capillosus CAPILLOSUS species Bacteroides capillosus.

C86170 BACTEROIDES Any bacterial organism that can be assigned to the Bacteroides cellulosolvens CELLULOSOLVENS species Bacteroides cellulosolvens.

C86171 BACTEROIDES EGGERTHII Any bacterial organism that can be assigned to the Bacteroides eggerthii species Bacteroides eggerthii.

C86172 BACTEROIDES FRAGILIS Any bacterial organism that can be assigned to the Bacteroides fragilis species Bacteroides fragilis.

C86173 BACTEROIDES FRAGILIS A bacteria that belongs to the Fragilis group of the Bacteroides fragilis Group GROUP genus Bacteroides.

C86174 BACTEROIDES NORDII Any bacterial organism that can be assigned to the Bacteroides nordii species Bacteroides nordii.

C86175 BACTEROIDES OVATUS Any bacterial organism that can be assigned to the Bacteroides ovatus species Bacteroides ovatus.

C86176 BACTEROIDES Any bacterial organism that can be assigned to the Bacteroides splanchnicus SPLANCHNICUS species Bacteroides splanchnicus.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 214 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C85491 - MICROORG - Microorganism Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C86177 BACTEROIDES STERCORIS BACTEROIDES Any bacterial organism that can be assigned to the Bacteroides stercoris FRAGILIS species Bacteroides stercoris. SUBSP. A

C86178 BACTEROIDES TECTUS BACTEROIDES Any bacterial organism that can be assigned to the Bacteroides tectus TECTUM species Bacteroides tectus.

C86179 BACTEROIDES Any bacterial organism that can be assigned to the Bacteroides thetaiotamicron THETAIOTAMICRON species Bacteroides thetaiotamicron.

C86180 BACTEROIDES UNIFORMIS Any bacterial organism that can be assigned to the Bacteroides uniformis species Bacteroides uniformis.

C86181 BACTEROIDES BACTEROIDES Any bacterial organism that can be assigned to the Bacteroides ureolyticus UREOLYTICUS CORRODENS species Bacteroides ureolyticus.

C86182 BACTEROIDES VULGATUS Any bacterial organism that can be assigned to the Bacteroides vulgatus species Bacteroides vulgatus.

C86184 BARTONELLA Any bacteria that is not assigned to the species level Bartonella but can be assigned to the Bartonella genus level.

C86185 BARTONELLA ROCHALIMAEA Any bacterial organism that can be assigned to the Bartonella elizabethae ELIZABETHAE ELIZABETHAE species Bartonella elizabethae.

C86186 BARTONELLA HENSELAE ROCHALIMAEA Any bacterial organism that can be assigned to the Bartonella henselae HENSELAE species Bartonella henselae.

C86187 BARTONELLA QUINTANA ROCHALIMAEA Any bacterial organism that can be assigned to the Bartonella quintana QUINTANA species Bartonella quintana.

C86188 BERGEYELLA Any bacteria that is not assigned to the species level Bergeyella but can be assigned to the Bergeyella genus level.

C86189 BERGEYELLA WEEKSELLA Any bacterial organism that can be assigned to the Bergeyella zoohelcum ZOOHELCUM ZOOHELCUM species Bergeyella zoohelcum.

C86191 BETA STREPTOCOCCUS, A non-taxonomic grouping of beta-hemolytic species Beta Streptococcus Group C GROUP C within the Streptococcus genus that are assigned to the C group.

C86192 BETA STREPTOCOCCUS, A non-taxonomic grouping of beta-hemolytic species Beta Streptococcus Group F GROUP F within the Streptococcus genus that are assigned to the F group.

C86193 BETA STREPTOCOCCUS, A non-taxonomic grouping of beta-hemolytic species Beta Streptococcus Group G GROUP G within the Streptococcus genus that are assigned to the G group.

C86194 BIFIDOBACTERIUM Any bacteria that is not assigned to the species level Bifidobacterium but can be assigned to the Bifidobacterium genus level.

C86195 BIFIDOBACTERIUM Any bacterial organism that can be assigned to the Bifidobacterium adolescentis ADOLESCENTIS species Bifidobacterium adolescentis.

C86196 BIFIDOBACTERIUM Any bacterial organism that can be assigned to the Bifidobacterium angulatum ANGULATUM species Bifidobacterium angulatum.

C86197 BIFIDOBACTERIUM Any bacterial organism that can be assigned to the Bifidobacterium bifidum BIFIDUM species Bifidobacterium bifidum.

C86198 BIFIDOBACTERIUM BIFIDOBACTER Any bacterial organism that can be assigned to the Bifidobacterium dentium DENTIUM IUM species Bifidobacterium dentium. APPENDICITIS

C86199 BIFIDOBACTERIUM Any bacterial organism that can be assigned to the Bifidobacterium longum LONGUM species Bifidobacterium longum.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 215 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C85491 - MICROORG - Microorganism Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C86200 BILOPHILA Any bacteria that is not assigned to the species level Bilophila but can be assigned to the Bilophila genus level.

C86201 BILOPHILA Any bacterial organism that can be assigned to the Bilophila wadsworthia WADSWORTHIA species Bilophila wadsworthia.

C86202 BORDETELLA Any bacteria that is not assigned to the species level Bordetella but can be assigned to the Bordetella genus level.

C86203 BORDETELLA AVIUM Any bacterial organism that can be assigned to the Bordetella avium species Bordetella avium.

C86204 BORDETELLA BORDETELLA Any bacterial organism that can be assigned to the Bordetella bronchiseptica BRONCHISEPTICA BRONCHICANI species Bordetella bronchiseptica. S

C86205 BORDETELLA Any bacterial organism that can be assigned to the Bordetella parapertussis PARAPERTUSSIS species Bordetella parapertussis.

C76205 BORDETELLA PERTUSSIS Any bacterial organism that can be assigned to the Bordetella pertussis species Bordetella pertussis.

C86206 BORRELIA Any bacteria that is not assigned to the species level Borrelia but can be assigned to the Borrelia genus level.

C76208 BORRELIA BURGDORFERI Any bacterial organism that can be assigned to the Borrelia burgdorferi species Borrelia burgdorferi.

C86207 BREVIBACILLUS Any bacteria that is not assigned to the species level Brevibacillus but can be assigned to the Brevibacillus genus level.

C86208 BREVIBACILLUS Any bacterial organism that can be assigned to the Brevibacillus laterosporus LATEROSPORUS species Brevibacillus laterosporus.

C86209 BREVIBACTERIUM Any bacteria that is not assigned to the species level Brevibacterium but can be assigned to the Brevibacterium genus level.

C86210 BREVIBACTERIUM CASEI Any bacterial organism that can be assigned to the Brevibacterium casei species Brevibacterium casei.

C86211 BREVIBACTERIUM Any bacterial organism that can be assigned to the Brevibacterium epidermidis EPIDERMIDIS species Brevibacterium epidermidis.

C86212 BREVUNDIMONAS Any bacteria that is not assigned to the species level Brevundimonas but can be assigned to the Brevundimonas genus level.

C86213 BREVUNDIMONAS PSEUDOMONA Any bacterial organism that can be assigned to the Brevundimonas diminuta DIMINUTA S DIMINUTA species Brevundimonas diminuta.

C86214 BREVUNDIMONAS PSEUDOMONA Any bacterial organism that can be assigned to the Brevundimonas vesicularis VESICULARIS S VESICULARIS species Brevundimonas vesicularis.

C86215 BRUCELLA Any bacteria that is not assigned to the species level Brucella but can be assigned to the Brucella genus level.

C86216 BRUCELLA ABORTUS Any bacterial organism that can be assigned to the Brucella abortus species Brucella abortus.

C86217 BRUCELLA CANIS Any bacterial organism that can be assigned to the Brucella canis species Brucella canis.

C86218 BRUCELLA MELITENSIS Any bacterial organism that can be assigned to the Brucella melitensis species Brucella melitensis.

C86219 BRUCELLA SUIS Any bacterial organism that can be assigned to the Brucella suis species Brucella suis.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 216 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C85491 - MICROORG - Microorganism Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C86220 BUDVICIA Any bacteria that is not assigned to the species level Budvicia but can be assigned to the Budvicia genus level.

C86221 BUDVICIA AQUATICA Any bacterial organism that can be assigned to the Budvicia aquatica species Budvicia aquatica.

C86222 BURKHOLDERIA Any bacteria that is not assigned to the species level Burkholderia but can be assigned to the Burkholderia genus level.

C86223 BURKHOLDERIA Any bacterial organism that can be assigned to the Burkholderia cenocepacia CENOCEPACIA species Burkholderia cenocepacia.

C76376 BURKHOLDERIA CEPACIA PSEUDOMONA Any bacterial organism that can be assigned to the Burkholderia cepacia S CEPACIA; species Burkholderia cepacia. CDC GROUP EO-1

C86224 BURKHOLDERIA CEPACIA A non-taxonomic grouping of bacteria assigned to and Burkholderia cepacia Complex COMPLEX including at least nine related species from the Burkholderia genus.

C86225 BURKHOLDERIA PSEUDOMONA Any bacterial organism that can be assigned to the Burkholderia gladioli GLADIOLI S GLADIOLI species Burkholderia gladioli.

C86226 BURKHOLDERIA MALLEI ACTINOBACILL Any bacterial organism that can be assigned to the Burkholderia mallei US MALLEI species Burkholderia mallei.

C86227 BURKHOLDERIA PSEUDOMONA Any bacterial organism that can be assigned to the Burkholderia pseudomallei PSEUDOMALLEI S species Burkholderia pseudomallei. PSEUDOMALL EI; BURKHOLDERI A PSEUDOMALL E

C86228 BUTTIAUXELLA Any bacteria that is not assigned to the species level Buttiauxella but can be assigned to the Buttiauxella genus level.

C86229 BUTTIAUXELLA AGRESTIS Any bacterial organism that can be assigned to the Buttiauxella agrestis species Buttiauxella agrestis.

C76211 CAMPYLOBACTER Any bacteria that is not assigned to the species level Campylobacter but can be assigned to the Campylobacter genus level.

C86230 CAMPYLOBACTER COLI Any bacterial organism that can be assigned to the Campylobacter coli species Campylobacter coli.

C86231 CAMPYLOBACTER CDC GROUP Any bacterial organism that can be assigned to the Campylobacter concisus CONCISUS EF-22 species Campylobacter concisus.

C86232 CAMPYLOBACTER WOLINELLA Any bacterial organism that can be assigned to the Campylobacter curvus CURVUS CURVA species Campylobacter curvus.

C86233 CAMPYLOBACTER FETUS VIBRIO FETUS Any bacterial organism that can be assigned to the Campylobacter fetus species Campylobacter fetus.

C86234 CAMPYLOBACTER BACTEROIDES Any bacterial organism that can be assigned to the Campylobacter gracilis GRACILIS GRACILIS species Campylobacter gracilis.

C86235 CAMPYLOBACTER JEJUNI Any bacterial organism that can be assigned to the Campylobacter jejuni species Campylobacter jejuni.

C86236 CAMPYLOBACTER LARI CAMPYLOBAC Any bacterial organism that can be assigned to the Campylobacter lari TER LARIDIS species Campylobacter lari.

C86237 CAMPYLOBACTER RECTUS WOLINELLA Any bacterial organism that can be assigned to the Campylobacter rectus RECTA species Campylobacter rectus.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 217 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C85491 - MICROORG - Microorganism Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C86238 CAMPYLOBACTER Any bacterial organism that can be assigned to the Campylobacter upsaliensis UPSALIENSIS species Campylobacter upsaliensis.

C76269 CAPNOCYTOPHAGA Any bacteria that is not assigned to the species level Capnocytophaga but can be assigned to the Capnocytophaga genus level.

C86239 CAPNOCYTOPHAGA CDC GROUP Any bacterial organism that can be assigned to the Capnocytophaga canimorsus CANIMORSUS DF-2 species Capnocytophaga canimorsus.

C86240 CAPNOCYTOPHAGA Any bacterial organism that can be assigned to the Capnocytophaga gingivalis GINGIVALIS species Capnocytophaga gingivalis.

C86241 CAPNOCYTOPHAGA Any bacterial organism that can be assigned to the Capnocytophaga ochracea OCHRACEA species Capnocytophaga ochracea.

C86242 CAPNOCYTOPHAGA Any bacterial organism that can be assigned to the Capnocytophaga sputigena SPUTIGENA species Capnocytophaga sputigena.

C86243 CARDIOBACTERIUM Any bacteria that is not assigned to the species level Cardiobacterium but can be assigned to the Cardiobacterium genus level.

C86244 CARDIOBACTERIUM CDC GROUP Any bacterial organism that can be assigned to the Cardiobacterium hominis HOMINIS IID species Cardiobacterium hominis.

C86245 CEDECEA Any bacteria that is not assigned to the species level Cedecea but can be assigned to the Cedecea genus level.

C86246 CEDECEA DAVISAE CDC ENTERIC Any bacterial organism that can be assigned to the Cedecea davisae GROUP 15 species Cedecea davisae.

C86247 CEDECEA LAPAGEI Any bacterial organism that can be assigned to the Cedecea lapagei species Cedecea lapagei.

C86248 CEDECEA NETERI CEDECEA Any bacterial organism that can be assigned to the Cedecea neteri SPECIES 4 species Cedecea neteri.

C86249 CELLULOMONAS Any bacteria that is not assigned to the species level Cellulomonas but can be assigned to the Cellulomonas genus level.

C86250 CELLULOMONAS HOMINIS Any bacterial organism that can be assigned to the Cellulomonas hominis species Cellulomonas hominis.

C86251 CELLULOSIMICROBIUM Any bacteria that is not assigned to the species level Cellulosimicrobium but can be assigned to the Cellulosimicrobium genus level.

C86252 CELLULOSIMICROBIUM OERSKOVIA Any bacterial organism that can be assigned to the Cellulosimicrobium cellulans CELLULANS XANTHINEOLY species Cellulosimicrobium cellulans. TICA; ARTHROBACTE R LUTEUS; CELLULOMON AS CELLULANS; NOCARDIA CELLULANS

C76271 CHLAMYDIA Any bacteria that is not assigned to the species level Chlamydia but can be assigned to the Chlamydia genus level.

C86253 CHLAMYDIA Any bacterial organism that can be assigned to the Chlamydia trachomatis TRACHOMATIS species Chlamydia trachomatis.

C86254 CHLAMYDOPHILA Any bacteria that is not assigned to the species level Chlamydophila but can be assigned to the Chlamydophila genus level.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 218 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C85491 - MICROORG - Microorganism Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C76272 CHLAMYDOPHILA CHLAMYDIA Any bacterial organism that can be assigned to the Chlamydophila pneumoniae PNEUMONIAE PNEUMONIAE species Chlamydophila pneumoniae.

C86255 CHLAMYDOPHILA CHLAMYDIA Any bacterial organism that can be assigned to the Chlamydophila psittaci PSITTACI PSITTACI species Chlamydophila psittaci.

C86256 CHROMOBACTERIUM Any bacteria that is not assigned to the species level Chromobacterium but can be assigned to the Chromobacterium genus level.

C86257 CHROMOBACTERIUM Any bacterial organism that can be assigned to the Chromobacterium violaceum VIOLACEUM species Chromobacterium violaceum.

C86258 CHRYSEOBACTERIUM Any bacteria that is not assigned to the species level Chryseobacterium but can be assigned to the Chryseobacterium genus level.

C86259 CHRYSEOBACTERIUM FLAVOBACTER Any bacterial organism that can be assigned to the Chryseobacterium gleum GLEUM IUM GLEUM species Chryseobacterium gleum.

C86260 CHRYSEOBACTERIUM FLAVOBACTER Any bacterial organism that can be assigned to the Chryseobacterium indologenes INDOLOGENES IUM species Chryseobacterium indologenes. INDOLOGENES

C86261 CHRYSEOMONAS Any bacteria that is not assigned to the species level Chryseomonas but can be assigned to the Chryseomonas genus level.

C76273 CITROBACTER Any bacteria that is not assigned to the species level Citrobacter but can be assigned to the Citrobacter genus level.

C86262 CITROBACTER LEVINEA Any bacterial organism that can be assigned to the Citrobacter amalonaticus AMALONATICUS AMALONATICA species Citrobacter amalonaticus.

C86263 CITROBACTER BRAAKII Any bacterial organism that can be assigned to the Citrobacter braakii species Citrobacter braakii.

C86264 CITROBACTER FARMERI CITROBACTER Any bacterial organism that can be assigned to the Citrobacter farmeri AMALONATICU species Citrobacter farmeri. S BIOGROUP 1

C86265 CITROBACTER FREUNDII COLOBACTRU Any bacterial organism that can be assigned to the Citrobacter freundii M FREUNDII species Citrobacter freundii.

C86266 CITROBACTER FREUNDII A non-taxonomic grouping of bacteria assigned to and Citrobacter freundii Complex COMPLEX including eight related species from the Citrobacter genus.

C86267 CITROBACTER KOSERI CITROBACTER Any bacterial organism that can be assigned to the Citrobacter koseri DIVERSUS species Citrobacter koseri.

C86268 CITROBACTER YOUNGAE Any bacterial organism that can be assigned to the Citrobacter youngae species Citrobacter youngae.

C76275 CLOSTRIDIUM Any bacteria that is not assigned to the species level Clostridium but can be assigned to the Clostridium genus level.

C86269 CLOSTRIDIUM Any bacterial organism that can be assigned to the Clostridium acetobutylicum ACETOBUTYLICUM species Clostridium acetobutylicum.

C86270 CLOSTRIDIUM BARATII CLOSTRIDIUM Any bacterial organism that can be assigned to the Clostridium baratii BARATI species Clostridium baratii.

C86271 CLOSTRIDIUM Any bacterial organism that can be assigned to the Clostridium beijerinckii BEIJERINCKII species Clostridium beijerinckii.

C86272 CLOSTRIDIUM Any bacterial organism that can be assigned to the Clostridium bifermentans BIFERMENTANS species Clostridium bifermentans.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 219 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C85491 - MICROORG - Microorganism Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C86273 CLOSTRIDIUM CLOSTRIDIUM Any bacterial organism that can be assigned to the Clostridium butyricum BUTYRICUM PSEUDOTETAN species Clostridium butyricum. ICUM

C86274 CLOSTRIDIUM CADAVERIS Any bacterial organism that can be assigned to the Clostridium cadaveris species Clostridium cadaveris.

C86275 CLOSTRIDIUM CELATUM Any bacterial organism that can be assigned to the Clostridium celatum species Clostridium celatum.

C86276 CLOSTRIDIUM CLOSTRIDIUM Any bacterial organism that can be assigned to the Clostridium clostridioforme CLOSTRIDIOFORME CLOSTRIDIIFO species Clostridium clostridioforme. RME

C86277 CLOSTRIDIUM Any bacterial organism that can be assigned to the Clostridium cochlearium COCHLEARIUM species Clostridium cochlearium.

C86278 CLOSTRIDIUM Any bacterial organism that can be assigned to the Clostridium cocleatum COCLEATUM species Clostridium cocleatum.

C76276 CLOSTRIDIUM DIFFICILE CLOSTRIDIUM Any bacterial organism that can be assigned to the Clostridium difficile DIFFICILIS species Clostridium difficile.

C86279 CLOSTRIDIUM FALLAX CLOSTRIDIUM Any bacterial organism that can be assigned to the Clostridium fallax PSEUDOFALLA species Clostridium fallax. X

C86280 CLOSTRIDIUM Any bacterial organism that can be assigned to the Clostridium glycolicum GLYCOLICUM species Clostridium glycolicum.

C86281 CLOSTRIDIUM Any bacterial organism that can be assigned to the Clostridium haemolyticum HAEMOLYTICUM species Clostridium haemolyticum.

C86282 CLOSTRIDIUM Any bacterial organism that can be assigned to the Clostridium histolyticum HISTOLYTICUM species Clostridium histolyticum.

C86283 CLOSTRIDIUM INNOCUUM Any bacterial organism that can be assigned to the Clostridium innocuum species Clostridium innocuum.

C86284 CLOSTRIDIUM LIMOSUM CLOSTRIDIUM Any bacterial organism that can be assigned to the Clostridium limosum SPECIES CDC species Clostridium limosum. GROUP P-1

C86285 CLOSTRIDIUM NOVYI Any bacterial organism that can be assigned to the Clostridium novyi species Clostridium novyi.

C86286 CLOSTRIDIUM Any bacterial organism that can be assigned to the Clostridium oceanicum OCEANICUM species Clostridium oceanicum.

C86287 CLOSTRIDIUM Any bacterial organism that can be assigned to the Clostridium paraputrificum PARAPUTRIFICUM species Clostridium paraputrificum.

C86288 CLOSTRIDIUM CLOSTRIDIUM Any bacterial organism that can be assigned to the Clostridium perfringens PERFRINGENS WELCHII species Clostridium perfringens.

C86289 CLOSTRIDIUM CLOSTRIDIUM Any bacterial organism that can be assigned to the Clostridium putrificum PUTRIFICUM LENTOPUTRES species Clostridium putrificum. CENS

C86290 CLOSTRIDIUM RAMOSUM ACTINOMYCES Any bacterial organism that can be assigned to the Clostridium ramosum RAMOSUS species Clostridium ramosum.

C86291 CLOSTRIDIUM RECTUM Any bacterial organism that can be assigned to the Clostridium rectum species Clostridium rectum.

C86292 CLOSTRIDIUM SEPTICUM Any bacterial organism that can be assigned to the Clostridium septicum species Clostridium septicum.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 220 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C85491 - MICROORG - Microorganism Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C86293 CLOSTRIDIUM SORDELLII Any bacterial organism that can be assigned to the Clostridium sordellii species Clostridium sordellii.

C86294 CLOSTRIDIUM Any bacterial organism that can be assigned to the Clostridium sporogenes SPOROGENES species Clostridium sporogenes.

C86295 CLOSTRIDIUM Any bacterial organism that can be assigned to the Clostridium subterminale SUBTERMINALE species Clostridium subterminale.

C86296 CLOSTRIDIUM BACTEROIDES Any bacterial organism that can be assigned to the Clostridium symbiosum SYMBIOSUM SYMBIOSUS species Clostridium symbiosum.

C86297 CLOSTRIDIUM TERTIUM Any bacterial organism that can be assigned to the Clostridium tertium species Clostridium tertium.

C86298 CLOSTRIDIUM TETANI Any bacterial organism that can be assigned to the Clostridium tetani species Clostridium tetani.

C86299 CLOSTRIDIUM Any bacterial organism that can be assigned to the Clostridium tyrobutyricum TYROBUTYRICUM species Clostridium tyrobutyricum.

C62584 COAGULASE NEGATIVE Any bacteria assigned to the genus Staphylococcus that Coagulase-Negative Staphylococcus STAPHYLOCOCCUS does not express the enzyme coagulase.

C62585 COAGULASE POSITIVE Any bacteria assigned to the genus Staphylococcus that Coagulase-Positive Staphylococcus STAPHYLOCOCCUS expresses the enzyme coagulase.

C86300 COLLINSELLA Any bacteria that is not assigned to the species level Collinsella but can be assigned to the Collinsella genus level.

C86301 COLLINSELLA EUBACTERIUM Any bacterial organism that can be assigned to the Collinsella aerofaciens AEROFACIENS AEROFACIENS species Collinsella aerofaciens.

C86302 COLLINSELLA Any bacterial organism that can be assigned to the Collinsella intestinalis INTESTINALIS species Collinsella intestinalis.

C86303 COMAMONAS Any bacteria that is not assigned to the species level Comamonas but can be assigned to the Comamonas genus level.

C86304 COMAMONAS TERRIGENA CDC GROUP Any bacterial organism that can be assigned to the Comamonas terrigena EF-19 species Comamonas terrigena.

C86305 COMAMONAS PSEUDOMONA Any bacterial organism that can be assigned to the Comamonas testosteroni TESTOSTERONI S species Comamonas testosteroni. TESTOSTERONI

C76308 CORYNEBACTERIUM Any bacteria that is not assigned to the species level Corynebacterium but can be assigned to the Corynebacterium genus level.

C86306 CORYNEBACTERIUM CORYNEBACTE Any bacterial organism that can be assigned to the Corynebacterium accolens ACCOLENS RIUM GROUP species Corynebacterium accolens. G-1

C86307 CORYNEBACTERIUM CORYNEBACTE Any bacterial organism that can be assigned to the Corynebacterium afermentans AFERMENTANS RIUM ANF-1 species Corynebacterium afermentans.

C86308 CORYNEBACTERIUM Any bacterial organism that can be assigned to the Corynebacterium amycolatum AMYCOLATUM species Corynebacterium amycolatum.

C86309 CORYNEBACTERIUM Any bacterial organism that can be assigned to the Corynebacterium argentoratense ARGENTORATENSE species Corynebacterium argentoratense.

C86310 CORYNEBACTERIUM Any bacterial organism that can be assigned to the Corynebacterium auris AURIS species Corynebacterium auris.

C86311 CORYNEBACTERIUM Any bacterial organism that can be assigned to the Corynebacterium bovis BOVIS species Corynebacterium bovis.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 221 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C85491 - MICROORG - Microorganism Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C86312 CORYNEBACTERIUM Any bacterial organism that can be assigned to the Corynebacterium diphtheriae DIPHTHERIAE species Corynebacterium diphtheriae.

C86313 CORYNEBACTERIUM Any bacterial organism that can be assigned to the Corynebacterium genitalium GENITALIUM species Corynebacterium genitalium.

C86955 CORYNEBACTERIUM Any bacterial organism that can be assigned to the Corynebacterium glucuronolyticum GLUCURONOLYTICUM species Corynebacterium glucuronolyticum.

C76307 CORYNEBACTERIUM CDC GROUP Any bacterial organism that can be assigned to the Corynebacterium jeikeium JEIKEIUM JK; species Corynebacterium jeikeium. CORYNEBACTE RIUM GROUP JK

C86314 CORYNEBACTERIUM Any bacterial organism that can be assigned to the Corynebacterium kutscheri KUTSCHERI species Corynebacterium kutscheri.

C86315 CORYNEBACTERIUM Any bacterial organism that can be assigned to the Corynebacterium macginleyi MACGINLEYI species Corynebacterium macginleyi.

C86316 CORYNEBACTERIUM BACTERIONEM Any bacterial organism that can be assigned to the Corynebacterium matruchotii MATRUCHOTII A species Corynebacterium matruchotii. MATRUCHOTII

C86317 CORYNEBACTERIUM Any bacterial organism that can be assigned to the Corynebacterium minutissimum MINUTISSIMUM species Corynebacterium minutissimum.

C86318 CORYNEBACTERIUM Any bacterial organism that can be assigned to the Corynebacterium pilosum PILOSUM species Corynebacterium pilosum.

C86319 CORYNEBACTERIUM Any bacterial organism that can be assigned to the Corynebacterium propinquum PROPINQUUM species Corynebacterium propinquum.

C86320 CORYNEBACTERIUM CORYNEBACTE Any bacterial organism that can be assigned to the Corynebacterium PSEUDODIPHTHERITICUM RIUM species Corynebacterium pseudodiphtheriticum. pseudodiphtheriticum HOFMANNII

C86321 CORYNEBACTERIUM Any bacterial organism that can be assigned to the Corynebacterium pseudotuberculosis PSEUDOTUBERCULOSIS species Corynebacterium pseudotuberculosis.

C86322 CORYNEBACTERIUM Any bacterial organism that can be assigned to the Corynebacterium renale RENALE species Corynebacterium renale.

C86323 CORYNEBACTERIUM Any bacterial organism that can be assigned to the Corynebacterium striatum STRIATUM species Corynebacterium striatum.

C86324 CORYNEBACTERIUM Any bacterial organism that can be assigned to the Corynebacterium ulcerans ULCERANS species Corynebacterium ulcerans.

C86325 CORYNEBACTERIUM CDC GROUP Any bacterial organism that can be assigned to the Corynebacterium urealyticum UREALYTICUM D2; species Corynebacterium urealyticum. CORYNEBACTE RIUM GROUP D-2

C86326 CORYNEBACTERIUM Any bacterial organism that can be assigned to the Corynebacterium xerosis XEROSIS species Corynebacterium xerosis.

C86327 CORYNEFORM CORYNEFORM Any bacteria whose shape is similar to those bacteria Coryneform Gram Positive Bacillus GRAM-POSITIVE BACILLUS GRAM-POSITIV assigned to the Corynebacterium genus and have a cell E ROD wall that contains low levels of peptidoglycan and stains pink with the Gram staining technique.

C76309 COXIELLA Any bacteria that is not assigned to the species level Coxiella but can be assigned to the Coxiella genus level.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 222 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C85491 - MICROORG - Microorganism Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C86328 COXIELLA BURNETII Any bacterial organism that can be assigned to the Coxiella burnetii species Coxiella burnetii.

C86329 CRONOBACTER ENTEROBACTE Any bacterial organism that can be assigned to the Cronobacter sakazakii SAKAZAKII R SAKAZAKII species Cronobacter sakazakii.

C86330 CUPRIAVIDUS Any bacteria that is not assigned to the species level Cupriavidus but can be assigned to the Cupriavidus genus level.

C86331 CUPRIAVIDUS PAUCULUS CDC GROUP Any bacterial organism that can be assigned to the Cupriavidus pauculus IVC-2; species Cupriavidus pauculus. WAUTERSIA PAUCULA; RALSTONIA PAUCULA

C86332 DELFTIA Any bacteria that is not assigned to the species level Delftia but can be assigned to the Delftia genus level.

C86333 DELFTIA ACIDOVORANS COMAMONAS Any bacterial organism that can be assigned to the Delftia acidovorans ACIDOVORANS species Delftia acidovorans. ; PSEUDOMONA S ACIDOVORANS

C86334 DERMABACTER Any bacteria that is not assigned to the species level Dermabacter but can be assigned to the Dermabacter genus level.

C86335 DERMABACTER HOMINIS Any bacterial organism that can be assigned to the Dermabacter hominis species Dermabacter hominis.

C86336 DERMACOCCUS MICROCOCCU Any bacterial organism that can be assigned to the Dermacoccus nishinomiyaensis NISHINOMIYAENSIS S species Dermacoccus nishinomiyaensis. NISHINOMIYAE NSIS

C86337 DERMATOPHILUS Any bacteria that is not assigned to the species level Dermatophilus but can be assigned to the Dermatophilus genus level.

C86338 DERMATOPHILUS Any bacterial organism that can be assigned to the Dermatophilus congolensis CONGOLENSIS species Dermatophilus congolensis.

C86339 DESULFOVIBRIO DESULFOMON Any bacteria that is not assigned to the species level Desulfovibrio AS SPECIES but can be assigned to the Desulfovibrio genus level.

C86340 DESULFOVIBRIO Any bacterial organism that can be assigned to the Desulfovibrio desulfuricans DESULFURICANS species Desulfovibrio desulfuricans.

C86341 DESULFOVIBRIO Any bacterial organism that can be assigned to the Desulfovibrio fairfieldensis FAIRFIELDENSIS species Desulfovibrio fairfieldensis.

C86342 DESULFOVIBRIO PIGER DESULFOMON Any bacterial organism that can be assigned to the Desulfovibrio piger AS PIGRA species Desulfovibrio piger.

C86343 DIPHTHEROID BACILLUS Any of a number of rod-shaped bacteria that resemble Diptheroid Bacillus Corynebacterium diphtheriae, either in morphology or etiology.

C86344 EDWARDSIELLA Any bacteria that is not assigned to the species level Edwardsiella but can be assigned to the Edwardsiella genus level.

C86345 EDWARDSIELLA Any bacterial organism that can be assigned to the Edwardsiella hoshinae HOSHINAE species Edwardsiella hoshinae.

C86346 EDWARDSIELLA ICTALURI Any bacterial organism that can be assigned to the Edwardsiella ictaluri species Edwardsiella ictaluri.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 223 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C85491 - MICROORG - Microorganism Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C86347 EDWARDSIELLA TARDA Any bacterial organism that can be assigned to the Edwardsiella tarda species Edwardsiella tarda.

C86348 EGGERTHELLA Any bacteria that is not assigned to the species level Eggerthella but can be assigned to the Eggerthella genus level.

C86349 EGGERTHELLA LENTA EUBACTERIUM Any bacterial organism that can be assigned to the Eggerthella lenta LENTUM species Eggerthella lenta.

C86350 EIKENELLA Any bacteria that is not assigned to the species level Eikenella but can be assigned to the Eikenella genus level.

C86351 EIKENELLA CORRODENS CDC GROUP Any bacterial organism that can be assigned to the Eikenella corrodens HB-1 species Eikenella corrodens.

C86352 ELIZABETHKINGIA Any bacteria that is not assigned to the species level Elizabethkingia but can be assigned to the Elizabethkingia genus level.

C86353 ELIZABETHKINGIA CHRYSEOBACT Any bacterial organism that can be assigned to the Elizabethkingia meningoceptica MENINGOCEPTICA ERIUM species Elizabethkingia meningoceptica. MENINGOSEPT ICUM; FLAVOBACTER IUM MENINGOSEPT ICUM

C86354 EMPEDOBACTER Any bacteria that is not assigned to the species level Empedobacter but can be assigned to the Empedobacter genus level.

C86355 EMPEDOBACTER BREVIS FLAVOBACTER Any bacterial organism that can be assigned to the Empedobacter brevis IUM BREVE species Empedobacter brevis.

C76310 ENTEROBACTER Any bacteria that is not assigned to the species level Enterobacter but can be assigned to the Enterobacter genus level.

C86356 ENTEROBACTER AEROBACTER Any bacterial organism that can be assigned to the Enterobacter aerogenes AEROGENES AEROGENES species Enterobacter aerogenes.

C86357 ENTEROBACTER ENTEROBACTE Any bacterial organism that can be assigned to the Enterobacter amnigenus AMNIGENUS R AMNIGENUS species Enterobacter amnigenus. I

C86358 ENTEROBACTER CDC ENTERIC Any bacterial organism that can be assigned to the Enterobacter asburiae ASBURIAE GROUP 17 species Enterobacter asburiae.

C86359 ENTEROBACTER CDC ENTERIC Any bacterial organism that can be assigned to the Enterobacter cancerogenus CANCEROGENUS GROUP 19; species Enterobacter cancerogenus. ENTEROBACTE R TAYLORAE

C86360 ENTEROBACTER CLOACAE ENTEROBACTE Any bacterial organism that can be assigned to the Enterobacter cloacae R CLOACAE species Enterobacter cloacae. STRAIN 1

C86361 ENTEROBACTER Any bacterial organism that can be assigned to the Enterobacter gergoviae GERGOVIAE species Enterobacter gergoviae.

C86362 ENTEROBACTER CDC ENTERIC Any bacterial organism that can be assigned to the Enterobacter hormaechei HORMAECHEI GROUP 75 species Enterobacter hormaechei.

C86363 ENTEROBACTER Any bacterial organism that can be assigned to the Enterobacter taylorae TAYLORAE species Enterobacter taylorae.

C76311 ENTEROCOCCUS PRESUMPTIVE Any bacteria that is not assigned to the species level Enterococcus ENTEROCOCC but can be assigned to the Enterococcus genus level. US

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 224 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C85491 - MICROORG - Microorganism Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C86364 ENTEROCOCCUS AVIUM STREPTOCOCC Any bacterial organism that can be assigned to the Enterococcus avium US AVIUM species Enterococcus avium.

C86365 ENTEROCOCCUS Any bacterial organism that can be assigned to the Enterococcus casseliflavus CASSELIFLAVUS species Enterococcus casseliflavus.

C86366 ENTEROCOCCUS DISPAR Any bacterial organism that can be assigned to the Enterococcus dispar species Enterococcus dispar.

C86367 ENTEROCOCCUS DURANS STREPTOCOCC Any bacterial organism that can be assigned to the Enterococcus durans US DURANS species Enterococcus durans.

C86368 ENTEROCOCCUS STREPTOCOCC Any bacterial organism that can be assigned to the Enterococcus faecalis FAECALIS US FAECALIS species Enterococcus faecalis.

C86369 ENTEROCOCCUS FAECIUM STREPTOCOCC Any bacterial organism that can be assigned to the Enterococcus faecium US FAECIUM species Enterococcus faecium.

C86370 ENTEROCOCCUS Any bacterial organism that can be assigned to the Enterococcus gallinarum GALLINARUM species Enterococcus gallinarum.

C86371 ENTEROCOCCUS HIRAE Any bacterial organism that can be assigned to the Enterococcus hirae species Enterococcus hirae.

C86372 ENTEROCOCCUS Any bacterial organism that can be assigned to the Enterococcus malodoratus MALODORATUS species Enterococcus malodoratus.

C86373 ENTEROCOCCUS MUNDTII Any bacterial organism that can be assigned to the Enterococcus mundtii species Enterococcus mundtii.

C86374 ENTEROCOCCUS Any bacterial organism that can be assigned to the Enterococcus pseudoavium PSEUDOAVIUM species Enterococcus pseudoavium.

C86375 ENTEROCOCCUS Any bacterial organism that can be assigned to the Enterococcus raffinosus RAFFINOSUS species Enterococcus raffinosus.

C86376 ERYSIPELOTHRIX ERYSIPELOTH Any bacteria that is not assigned to the species level Erysipelothrix RIX INSIDIOSA but can be assigned to the Erysipelothrix genus level.

C86377 ERYSIPELOTHRIX Any bacterial organism that can be assigned to the Erysipelothrix rhusiopathiae RHUSIOPATHIAE species Erysipelothrix rhusiopathiae.

C77208 ESCHERICHIA Any bacteria that is not assigned to the species level Escherichia but can be assigned to the Escherichia genus level.

C86378 ESCHERICHIA ALBERTII Any bacterial organism that can be assigned to the Escherichia albertii species Escherichia albertii.

C86379 ESCHERICHIA BLATTAE Any bacterial organism that can be assigned to the Escherichia blattae species Escherichia blattae.

C14206 ESCHERICHIA COLI E. COLI Any bacterial organism that can be assigned to the Escherichia coli species Escherichia coli.

C86881 ESCHERICHIA COLI O111 Any bacterial organism that can be assigned to the Escherichia coli strain O111 species Escherichia coli and strain O111.

C86882 ESCHERICHIA COLI O157 Any bacterial organism that can be assigned to the Escherichia coli strain O157 (NOT H7) species Escherichia coli and strain O157.

C86883 ESCHERICHIA COLI Any bacterial organism that can be assigned to the Escherichia coli strain O157:H7 O157:H7 species Escherichia coli and strain O157:H7.

C86884 ESCHERICHIA COLI O26 Any bacterial organism that can be assigned to the Escherichia coli strain O26 species Escherichia coli and strain O26.

C86380 ESCHERICHIA FERGUSONII CDC ENTERIC Any bacterial organism that can be assigned to the Escherichia fergusonii GROUP 10 species Escherichia fergusonii.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 225 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C85491 - MICROORG - Microorganism Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C86381 ESCHERICHIA HERMANNII CDC ENTERIC Any bacterial organism that can be assigned to the Escherichia hermannii GROUP 11 species Escherichia hermannii.

C86382 ESCHERICHIA VULNERIS CDC ENTERIC Any bacterial organism that can be assigned to the Escherichia vulneris GROUP 1 species Escherichia vulneris.

C86383 EUBACTERIUM Any bacteria that is not assigned to the species level Eubacterium but can be assigned to the Eubacterium genus level.

C86384 EUBACTERIUM Any bacterial organism that can be assigned to the Eubacterium adactolyticum ADACTOLYTICUM species Eubacterium adactolyticum.

C86385 EUBACTERIUM Any bacterial organism that can be assigned to the Eubacterium contortum CONTORTUM species Eubacterium contortum.

C86386 EUBACTERIUM LIMOSUM Any bacterial organism that can be assigned to the Eubacterium limosum species Eubacterium limosum.

C86387 EUBACTERIUM NODATUM Any bacterial organism that can be assigned to the Eubacterium nodatum species Eubacterium nodatum.

C86388 EUBACTERIUM RECTALE Any bacterial organism that can be assigned to the Eubacterium rectale species Eubacterium rectale.

C86389 EUBACTERIUM Any bacterial organism that can be assigned to the Eubacterium ventriosum VENTRIOSUM species Eubacterium ventriosum.

C86390 EWINGELLA Any bacteria that is not assigned to the species level Ewingella but can be assigned to the Ewingella genus level.

C86391 EWINGELLA AMERICANA CDC ENTERIC Any bacterial organism that can be assigned to the Ewingella americana GROUP 40 species Ewingella americana.

C86885 EXIGUOBACTERIUM Any bacteria that is not assigned to the species level Exiguobacterium but can be assigned to the Exiguobacterium genus level.

C86886 EXIGUOBACTERIUM BREVIBACTERI Any bacterial organism that can be assigned to the Exiguobacterium acetylicum ACETYLICUM UM species Exiguobacterium acetylicum. ACETYLICUM

C86392 FACKLAMIA Any bacteria that is not assigned to the species level Facklamia but can be assigned to the Facklamia genus level.

C86393 FAECALIBACTERIUM Any bacteria that is not assigned to the species level Faecalibacterium but can be assigned to the Faecalibacterium genus level.

C86394 FAECALIBACTERIUM FUSOBACTERI Any bacterial organism that can be assigned to the Faecalibacterium prausnitzii PRAUSNITZII UM species Faecalibacterium prausnitzii. PRAUSNITZII

C86395 FERMENTATIVE FERMENTATIV Any rod-shaped, anaerobic bacteria that can convert Fermentative Gram Negative GRAM-NEGATIVE E carbohydrates into acids and alcohols and has a cell Bacillus BACILLUS GRAM-NEGATI wall contains low levels of peptidoglycan and stains VE ROD pink with the Gram staining technique.

C86887 FINEGOLDIA Any bacteria that is not assigned to the species level Finegoldia but can be assigned to the Finegoldia genus level.

C86888 FINEGOLDIA MAGNA PEPTOSTREPT Any bacterial organism that can be assigned to the Finegoldia magna OCOCCUS species Finegoldia magna. MAGNUS

C76320 FLAVOBACTERIUM Any bacteria that is not assigned to the species level Flavobacterium but can be assigned to the Flavobacterium genus level.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 226 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C85491 - MICROORG - Microorganism Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C86396 FRANCISELLA Any bacteria that is not assigned to the species level Francisella but can be assigned to the Francisella genus level.

C86397 FRANCISELLA PASTEURELLA Any bacterial organism that can be assigned to the Francisella tularensis TULARENSIS TULARENSIS species Francisella tularensis.

C76323 FUSOBACTERIUM Any bacteria that is not assigned to the species level Fusobacterium but can be assigned to the Fusobacterium genus level.

C86398 FUSOBACTERIUM Any bacterial organism that can be assigned to the Fusobacterium gonidiaformans GONIDIAFORMANS species Fusobacterium gonidiaformans.

C86399 FUSOBACTERIUM Any bacterial organism that can be assigned to the Fusobacterium mortiferum MORTIFERUM species Fusobacterium mortiferum.

C86400 FUSOBACTERIUM Any bacterial organism that can be assigned to the Fusobacterium necrogenes NECROGENES species Fusobacterium necrogenes.

C86401 FUSOBACTERIUM Any bacterial organism that can be assigned to the Fusobacterium necrophorum NECROPHORUM species Fusobacterium necrophorum.

C86404 FUSOBACTERIUM Any bacterial organism that can be assigned to the Fusobacterium nucleatum NUCLEATUM species Fusobacterium nucleatum.

C86405 FUSOBACTERIUM RUSSII Any bacterial organism that can be assigned to the Fusobacterium russii species Fusobacterium russii.

C86406 FUSOBACTERIUM Any bacterial organism that can be assigned to the Fusobacterium ulcerans ULCERANS species Fusobacterium ulcerans.

C86407 FUSOBACTERIUM VARIUM FUSOBACTERI Any bacterial organism that can be assigned to the Fusobacterium varium UM species Fusobacterium varium. PSEUDONECR OPHORUM; FUSOBACTERI UM NECROPHORU M BIOVAR C

C86409 GARDNERELLA Any bacteria that is not assigned to the species level Gardnerella but can be assigned to the Gardnerella genus level.

C86410 GARDNERELLA CORYNEBACTE Any bacterial organism that can be assigned to the Gardnerella vaginalis VAGINALIS RIUM species Gardnerella vaginalis. VAGINALIS

C86889 GEMELLA Any bacteria that is not assigned to the species level Gemella but can be assigned to the Gemella genus level.

C86890 GEMELLA BERGERI Any bacterial organism that can be assigned to the Gemella bergeri species Gemella bergeri.

C86891 GEMELLA HAEMOLYSANS NEISSERIA Any bacterial organism that can be assigned to the Gemella haemolysans HAEMOLYSAN species Gemella haemolysans. S

C86892 GEMELLA MORBILLORUM STREPTOCOCC Any bacterial organism that can be assigned to the Gemella morbillorum US species Gemella morbillorum. MORBILLORU M

C86893 GEMELLA SANGUINIS Any bacterial organism that can be assigned to the Gemella sanguinis species Gemella sanguinis.

C86411 GLOBICATELLA Any bacteria that is not assigned to the species level Globicatella but can be assigned to the Globicatella genus level.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 227 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C85491 - MICROORG - Microorganism Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C86412 GLOBICATELLA GLOBICATELL Any bacterial organism that can be assigned to the Globicatella sanguinis SANGUINIS A SANGUIS species Globicatella sanguinis.

C86413 GLOBICATELLA Any bacterial organism that can be assigned to the Globicatella sulfidifaciens SULFIDIFACIENS species Globicatella sulfidifaciens.

C86414 GORDONIA Any bacteria that is not assigned to the species level Gordonia but can be assigned to the Gordonia genus level.

C86415 GORDONIA AICHIENSIS TSUKAMUREL Any bacterial organism that can be assigned to the Gordonia aichiensis LA AICHIENSIS; species Gordonia aichiensis. GORDONA AICHIENSIS

C86416 GORDONIA BRONCHIALIS RHODOCOCCU Any bacterial organism that can be assigned to the Gordonia bronchialis S species Gordonia bronchialis. BRONCHIALIS; GORDONA BRONCHIALIS

C86417 GORDONIA RHODOCOCCU Any bacterial organism that can be assigned to the Gordonia rubripertincta RUBRIPERTINCTA S species Gordonia rubripertincta. RUBRIPERTINC TA; GORDONA RUBROPERTIN CTA

C86418 GORDONIA SPUTI GORDONA Any bacterial organism that can be assigned to the Gordonia sputi SPUTI species Gordonia sputi.

C86419 GORDONIA TERRAE RHODOCOCCU Any bacterial organism that can be assigned to the Gordonia terrae S TERRAE; species Gordonia terrae. GORDONA TERRAE

C86420 GRACILIBACILLUS Any bacteria that is not assigned to the species level Gracilibacillus but can be assigned to the Gracilibacillus genus level.

C86421 GRAM-NEGATIVE Any rod-shaped bacteria that contains low levels of Gram Negative Bacillus BACILLUS peptidoglycan in its cell wall and stains pink with the Gram staining technique.

C86422 GRAM-NEGATIVE COCCUS Any spherical-shaped bacteria that contains low levels Gram Negative Coccus of peptidoglycan in its cell wall and stains pink with the Gram staining technique.

C62589 GRAM-POSITIVE BACILLUS Any rod-shaped bacteria that has a peptidoglycan-rich Gram-Positive Rod cell wall that stains dark purple with the Gram staining technique.

C86424 GRAM-POSITIVE COCCUS Any spherical-shaped bacteria that has a Gram Positive Coccus peptidoglycan-rich cell wall that stains dark purple with the Gram staining technique.

C86425 GRANULICATELLA Any bacteria that is not assigned to the species level Granulicatella but can be assigned to the Granulicatella genus level.

C86426 GRANULICATELLA ABIOTROPHIA Any bacterial organism that can be assigned to the Granulicatella adiacens ADIACENS ADJACENS; species Granulicatella adiacens. STREPTOCOCC US ADJACENS

C86427 GRIMONTIA HOLLISAE VIBRIO Any bacterial organism that can be assigned to the Grimontia hollisae HOLLISAE species Grimontia hollisae.

C76324 HAEMOPHILUS Any bacteria that is not assigned to the species level Haemophilus but can be assigned to the Haemophilus genus level.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 228 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C85491 - MICROORG - Microorganism Codelist extensible: Yes

CDISC NCI CodeCDISC Submission Value SynonymCDISC DefinitionNCI Preferred Term

C86428 HAEMOPHILUS Any bacterial organism that can be assigned to the Haemophilus aegyptius AEGYPTIUS species Haemophilus aegyptius.

C86429 HAEMOPHILUS Any bacterial organism that can be assigned to the Haemophilus haemoglobinophilus HAEMOGLOBINOPHILUS species Haemophilus haemoglobinophilus.

C86430 HAEMOPHILUS Any bacterial organism that can be assigned to the Haemophilus haemolyticus HAEMOLYTICUS species Haemophilus haemolyticus.

C86431 HAEMOPHILUS H-FLUAny bacterial organism that can be assigned to the Haemophilus influenzae INFLUENZAE species Haemophilus influenzae.

C86432 HAEMOPHILUS Any bacterial organism that can be assigned to the Haemophilus parahaemolyticus PARAHAEMOLYTICUS species Haemophilus parahaemolyticus.

C86433 HAEMOPHILUS HEMOPHILUS Any bacterial organism that can be assigned to the Haemophilus parainfluenzae PARAINFLUENZAE PARAINFLUEN species Haemophilus parainfluenzae. ZAE

C86434HAFNIAAny bacteria that is not assigned to the species level Hafnia but can be assigned to the Hafnia genus level.

C86435 HAFNIA ALVEIENTEROBACTE Any bacterial organism that can be assigned to the Hafnia alvei R ALVEI species Hafnia alvei.

C86436 HALOBACILLUSAny bacteria that is not assigned to the species level Halobacillus but can be assigned to the Halobacillus genus level.

C86873 HELCOCOCCUSAny bacteria that is not assigned to the species level Helcococcus but can be assigned to the Helcococcus genus level.

C86878 HELCOCOCCUS KUNZIIAny bacterial organism that can be assigned to the Helcococcus kunzii species Helcococcus kunzii.

C86879 HELCOCOCCUS Any bacterial organism that can be assigned to the Helcococcus pyogenes PYOGENES species Helcococcus pyogenes.

C86880 HELCOCOCCUS Any bacterial organism that can be assigned to the Helcococcus sueciensis SUECIENSIS species Helcococcus sueciensis.

C14296 HELICOBACTERAny bacteria that is not assigned to the species level Helicobacter but can be assigned to the Helicobacter genus level.

C86437 HELICOBACTER CINAEDICAMPYLOBAC Any bacterial organism that can be assigned to the Helicobacter cinaedi TER CINAEDI species Helicobacter cinaedi.

C14330 HELICOBACTER FELISH. FELISAny bacterial organism that can be assigned to the Helicobacter felis species Helicobacter felis.

C86438 HELICOBACTER CAMPYLOBAC Any bacterial organism that can be assigned to the Helicobacter fennelliae FENNELLIAE TER species Helicobacter fennelliae. FENNELLIAE

C86439HELICOBACTER CAMPYLOBAC Any bacterial organism that can be assigned to the Helicobacter mustelae MUSTELAE TER species Helicobacter mustelae. MUSTELAE

C14289HELICOBACTER PYLORIH. PYLORI; Any bacterial organism that can be assigned to the Helicobacter pylori CAMPYLOBAC species Helicobacter pylori. TER PYLORI

C86440HELICOBACTER RAPPINIFLEXISPIRA Any bacterial organism that can be assigned to the Helicobacter rappini RAPPINI species Helicobacter rappini.

C86441 HISTOPHILUS SOMNIHAEMOPHILUS Any bacterial organism that can be assigned to the SOMNUS species Histophilus somni.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 229 of 431 -A> CDISC Controlled Terminology SDTM - 2012-03-23 C85491 - MICROORG - Microorganism Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C86442 HOLDEMANIA Any bacteria that is not assigned to the species level Holdemania but can be assigned to the Holdemania genus level.

C86443 HOLDEMANIA FILIFORMIS Any bacterial organism that can be assigned to the Holdemania filiformis species Holdemania filiformis.

C86444 INQUILINUS Any bacteria that is not assigned to the species level Inquilinus but can be assigned to the Inquilinus genus level.

C86445 INQUILINUS LIMOSUS Any bacterial organism that can be assigned to the Inquilinus limosus species Inquilinus limosus.

C86446 JEOTGALIBACILLUS Any bacteria that is not assigned to the species level Jeotgalibacillus but can be assigned to the Jeotgalibacillus genus level.

C86447 JOHNSONELLA Any bacteria that is not assigned to the species level Johnsonella but can be assigned to the Johnsonella genus level.

C86448 JOHNSONELLA IGNAVA Any bacterial organism that can be assigned to the Johnsonella ignava species Johnsonella ignava.

C86449 KINGELLA Any bacteria that is not assigned to the species level Kingella but can be assigned to the Kingella genus level.

C86450 KINGELLA DENITRIFICANS CDC GROUP Any bacterial organism that can be assigned to the Kingella denitrificans TM-1 species Kingella denitrificans.

C86451 KINGELLA KINGAE MORAXELLA Any bacterial organism that can be assigned to the Kingella kingae KINGAE species Kingella kingae.

C86452 KINGELLA ORALIS Any bacterial organism that can be assigned to the Kingella oralis species Kingella oralis.

C86453 KINGELLA POTUS Any bacterial organism that can be assigned to the Kingella potus species Kingella potus.

C28165 KLEBSIELLA Any bacteria that is not assigned to the species level Klebsiella but can be assigned to the Klebsiella genus level.

C86454 KLEBSIELLA Any bacterial organism that can be assigned to the Klebsiella granulomatis GRANULOMATIS species Klebsiella granulomatis.

C86455 KLEBSIELLA OXYTOCA K. OXYTOCA Any bacterial organism that can be assigned to the Klebsiella oxytoca species Klebsiella oxytoca.

C86456 KLEBSIELLA OZAENAE KLEBSIELLA Any bacterial organism that can be assigned to the Klebsiella ozaenae PNEUMONIAE species Klebsiella ozaenae. SUBSP. OZAENAE

C86457 KLEBSIELLA K. Any bacterial organism that can be assigned to the Klebsiella pneumoniae PNEUMONIAE PNEUMONIAE species Klebsiella pneumoniae.

C86458 KLEBSIELLA KLEBSIELLA Any bacterial organism that can be assigned to the Klebsiella rhinoscleromatis RHINOSCLEROMATIS PNEUMONIAE species Klebsiella rhinoscleromatis. SUBSP. RHINOSCLERO MATIS

C86459 KLEBSIELLA Any bacterial organism that can be assigned to the Klebsiella singaporensis SINGAPORENSIS species Klebsiella singaporensis.

C86460 KLEBSIELLA VARIICOLA Any bacterial organism that can be assigned to the Klebsiella variicola species Klebsiella variicola.

C86461 KLUYVERA Any bacteria that is not assigned to the species level Kluyvera but can be assigned to the Kluyvera genus level.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 230 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C85491 - MICROORG - Microorganism Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C86462 KLUYVERA ASCORBATA CDC ENTERIC Any bacterial organism that can be assigned to the Kluyvera ascorbata GROUP 8 species Kluyvera ascorbata.

C86463 KLUYVERA Any bacterial organism that can be assigned to the Kluyvera cryocrescens CRYOCRESCENS species Kluyvera cryocrescens.

C86464 KLUYVERA GEORGIANA Any bacterial organism that can be assigned to the Kluyvera georgiana species Kluyvera georgiana.

C86465 KLUYVERA INTERMEDIA ENTEROBACTE Any bacterial organism that can be assigned to the Kluyvera intermedia R species Kluyvera intermedia. INTERMEDIUM ; ENTEROBACTE R INTERMEDIUS; KLUYVERA COCHLEAE

C86466 KNOELLIA Any bacteria that is not assigned to the species level Knoellia but can be assigned to the Knoellia genus level.

C86467 KOCURIA Any bacteria that is not assigned to the species level Kocuria but can be assigned to the Kocuria genus level.

C86468 KOCURIA KRISTINAE MICROCOCCU Any bacterial organism that can be assigned to the Kocuria kristinae S KRISTINAE species Kocuria kristinae.

C86469 KOCURIA ROSEA Any bacterial organism that can be assigned to the Kocuria rosea species Kocuria rosea.

C86470 KOCURIA VARIANS Any bacterial organism that can be assigned to the Kocuria varians species Kocuria varians.

C86471 KURTHIA Any bacteria that is not assigned to the species level Kurthia but can be assigned to the Kurthia genus level.

C86472 KYTOCOCCUS Any bacteria that is not assigned to the species level Kytococcus but can be assigned to the Kytococcus genus level.

C86473 KYTOCOCCUS Any bacterial organism that can be assigned to the Kytococcus sedentarius SEDENTARIUS species Kytococcus sedentarius.

C76352 LACTOBACILLUS Any bacteria that is not assigned to the species level Lactobacillus but can be assigned to the Lactobacillus genus level.

C86474 LACTOBACILLUS Any bacterial organism that can be assigned to the Lactobacillus acidophilus ACIDOPHILUS species Lactobacillus acidophilus.

C86475 LACTOBACILLUS BREVIS Any bacterial organism that can be assigned to the Lactobacillus brevis species Lactobacillus brevis.

C86476 LACTOBACILLUS CASEI Any bacterial organism that can be assigned to the Lactobacillus casei species Lactobacillus casei.

C86477 LACTOBACILLUS LACTOBACILL Any bacterial organism that can be assigned to the Lactobacillus catenaformis CATENAFORMIS US species Lactobacillus catenaformis. CATENAFORM E

C86478 LACTOBACILLUS Any bacterial organism that can be assigned to the Lactobacillus fermentum FERMENTUM species Lactobacillus fermentum.

C86479 LACTOBACILLUS Any bacterial organism that can be assigned to the Lactobacillus gallinarum GALLINARUM species Lactobacillus gallinarum.

C86480 LACTOBACILLUS JENSENII Any bacterial organism that can be assigned to the Lactobacillus jensenii species Lactobacillus jensenii.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 231 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C85491 - MICROORG - Microorganism Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C86481 LACTOBACILLUS Any bacterial organism that can be assigned to the Lactobacillus johnsonii JOHNSONII species Lactobacillus johnsonii.

C86482 LACTOBACILLUS Any bacterial organism that can be assigned to the Lactobacillus salivarius SALIVARIUS species Lactobacillus salivarius.

C86483 LACTOCOCCUS DOEDERLEIN Any bacteria that is not assigned to the species level Lactococcus BACILLUS but can be assigned to the Lactococcus genus level.

C86484 LACTOCOCCUS GARVIEAE Any bacterial organism that can be assigned to the Lactococcus garvieae species Lactococcus garvieae.

C86485 LACTOCOCCUS LACTIS Any bacterial organism that can be assigned to the Lactococcus lactis species Lactococcus lactis.

C86486 LECLERCIA Any bacteria that is not assigned to the species level Leclercia but can be assigned to the Leclercia genus level.

C86487 LECLERCIA CDC ENTERIC Any bacterial organism that can be assigned to the Leclercia adecarboxylata ADECARBOXYLATA GROUP 41 species Leclercia adecarboxylata.

C76353 LEGIONELLA Any bacteria that is not assigned to the species level Legionella but can be assigned to the Legionella genus level.

C86488 LEGIONELLA Any bacterial organism that can be assigned to the Legionella longbeachae LONGBEACHAE species Legionella longbeachae.

C86489 LEGIONELLA Any bacterial organism that can be assigned to the Legionella pneumophila PNEUMOPHILA species Legionella pneumophila.

C86490 LEIFSONIA Any bacteria that is not assigned to the species level Leifsonia but can be assigned to the Leifsonia genus level.

C86491 LEIFSONIA AQUATICA CORYNEBACTE Any bacterial organism that can be assigned to the Leifsonia aquatica RIUM species Leifsonia aquatica. AQUATICUM

C86492 LEMINORELLA Any bacteria that is not assigned to the species level Leminorella but can be assigned to the Leminorella genus level.

C86493 LEMINORELLA GRIMONTII CDC ENTERIC Any bacterial organism that can be assigned to the Leminorella grimontii GROUP 57 species Leminorella grimontii.

C86494 LEMINORELLA RICHARDII Any bacterial organism that can be assigned to the Leminorella richardii species Leminorella richardii.

C76355 LEPTOSPIRA Any bacteria that is not assigned to the species level Leptospira but can be assigned to the Leptospira genus level.

C76357 LEUCONOSTOC Any bacteria that is not assigned to the species level Leuconostoc but can be assigned to the Leuconostoc genus level.

C86495 LEUCONOSTOC CITREUM Any bacterial organism that can be assigned to the Leuconostoc citreum species Leuconostoc citreum.

C86496 LEUCONOSTOC LACTIS Any bacterial organism that can be assigned to the Leuconostoc lactis species Leuconostoc lactis.

C86497 LEUCONOSTOC Any bacterial organism that can be assigned to the Leuconostoc mesenteroides MESENTEROIDES species Leuconostoc mesenteroides.

C86498 LEUCONOSTOC Any bacterial organism that can be assigned to the Leuconostoc pseudomesenteroides PSEUDOMESENTEROIDES species Leuconostoc pseudomesenteroides.

C76359 LISTERIA Any bacteria that is not assigned to the species level Listeria but can be assigned to the Listeria genus level.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 232 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C85491 - MICROORG - Microorganism Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C86499 LISTERIA GRAYI Any bacterial organism that can be assigned to the Listeria grayi species Listeria grayi.

C86500 LISTERIA INNOCUA Any bacterial organism that can be assigned to the Listeria innocua species Listeria innocua.

C86501 LISTERIA IVANOVII LISTERIA Any bacterial organism that can be assigned to the Listeria ivanovii MONOCYTOGE species Listeria ivanovii. NES SEROVAR 5

C86502 LISTERIA Any bacterial organism that can be assigned to the Listeria monocytogenes MONOCYTOGENES species Listeria monocytogenes.

C86503 LISTERIA SEELIGERI Any bacterial organism that can be assigned to the Listeria seeligeri species Listeria seeligeri.

C86504 LISTERIA WELSHIMERI Any bacterial organism that can be assigned to the Listeria welshimeri species Listeria welshimeri.

C86505 MACROCOCCUS Any bacteria that is not assigned to the species level Macrococcus but can be assigned to the Macrococcus genus level.

C86506 MACROCOCCUS STAPHYLOCOC Any bacterial organism that can be assigned to the Macrococcus caseolyticus CASEOLYTICUS CUS species Macrococcus caseolyticus. CASEOLYTICU S

C86507 MANNHEIMIA Any bacteria that is not assigned to the species level Mannheimia but can be assigned to the Mannheimia genus level.

C86508 MANNHEIMIA PASTEURELLA Any bacterial organism that can be assigned to the Mannheimia haemolytica HAEMOLYTICA HAEMOLYTICA species Mannheimia haemolytica.

C86895 MEGASPHAERA Any bacteria that is not assigned to the species level Megasphaera but can be assigned to the Megasphaera genus level.

C86896 MEGASPHAERA ELSDENII PEPTOSTREPT Any bacterial organism that can be assigned to the Megasphaera elsdenii OCOCCUS species Megasphaera elsdenii. ELSDENII

C76361 METHYLOBACTERIUM Any bacteria that is not assigned to the species level Methylobacterium but can be assigned to the Methylobacterium genus level.

C86510 METHYLOBACTERIUM PSEUDOMONA Any bacterial organism that can be assigned to the Methylobacterium mesophilicum MESOPHILICUM S species Methylobacterium mesophilicum. MESOPHILICA

C85511 MICROBACTERIUM CDC Any bacteria that is not assigned to the species level Microbacterium CORYNEFORM but can be assigned to the Microbacterium genus level. GROUP A-4, A-5

C86512 MICROBACTERIUM Any bacterial organism that can be assigned to the Microbacterium paraoxydans PARAOXYDANS species Microbacterium paraoxydans.

C77086 MICROCOCCUS Any bacteria that is not assigned to the species level Micrococcus but can be assigned to the Micrococcus genus level.

C86513 MICROCOCCUS LUTEUS SARCINA Any bacterial organism that can be assigned to the Micrococcus luteus LUTEA species Micrococcus luteus.

C86514 MICROCOCCUS LYLAE Any bacterial organism that can be assigned to the Micrococcus lylae species Micrococcus lylae.

C86515 MITSUOKELLA Any bacteria that is not assigned to the species level Mitsuokella but can be assigned to the Mitsuokella genus level.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 233 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C85491 - MICROORG - Microorganism Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C86516 MITSUOKELLA Any bacterial organism that can be assigned to the Mitsuokella multacida MULTACIDA species Mitsuokella multacida.

C86517 MOBILUNCUS Any bacteria that is not assigned to the species level Mobiluncus but can be assigned to the Mobiluncus genus level.

C86518 MOBILUNCUS CURTISII Any bacterial organism that can be assigned to the Mobiluncus curtisii species Mobiluncus curtisii.

C86519 MOBILUNCUS MULIERIS Any bacterial organism that can be assigned to the Mobiluncus mulieris species Mobiluncus mulieris.

C86520 MOELLERELLA Any bacteria that is not assigned to the species level Moellerella but can be assigned to the Moellerella genus level.

C86521 MOELLERELLA CDC ENTERIC Any bacterial organism that can be assigned to the Moellerella wisconsensis WISCONSENSIS GROUP 46 species Moellerella wisconsensis.

C86898 MOGIBACTERIUM Any bacteria that is not assigned to the species level Mogibacterium but can be assigned to the Mogibacterium genus level.

C86899 MOGIBACTERIUM EUBACTERIUM Any bacterial organism that can be assigned to the Mogibacterium timidum TIMIDUM TIMIDUM species Mogibacterium timidum.

C86009 MORAXELLA BRANHAMELL Any bacteria that is not assigned to the species level Moraxella A SPECIES but can be assigned to the Moraxella genus level.

C86523 MORAXELLA ATLANTAE CDC GROUP Any bacterial organism that can be assigned to the Moraxella atlantae M-3 species Moraxella atlantae.

C86524 MORAXELLA BOVIS Any bacterial organism that can be assigned to the Moraxella bovis species Moraxella bovis.

C86525 MORAXELLA CANIS Any bacterial organism that can be assigned to the Moraxella canis species Moraxella canis.

C76210 MORAXELLA BRANHAMELL Any bacterial organism that can be assigned to the Moraxella catarrhalis CATARRHALIS A species Moraxella catarrhalis. CATARRHALIS

C86526 MORAXELLA LACUNATA MORAXELLA Any bacterial organism that can be assigned to the Moraxella lacunata LIQUEFACIENS species Moraxella lacunata.

C86527 MORAXELLA LINCOLNII Any bacterial organism that can be assigned to the Moraxella lincolnii species Moraxella lincolnii.

C86528 MORAXELLA Any bacterial organism that can be assigned to the Moraxella nonliquefaciens NONLIQUEFACIENS species Moraxella nonliquefaciens.

C86529 MORAXELLA OBLONGA Any bacterial organism that can be assigned to the Moraxella oblonga species Moraxella oblonga.

C86530 MORAXELLA OSLOENSIS Any bacterial organism that can be assigned to the Moraxella osloensis species Moraxella osloensis.

C86531 MORGANELLA Any bacteria that is not assigned to the species level Morganella but can be assigned to the Morganella genus level.

C86015 MORGANELLA MORGANII PROTEUS Any bacterial organism that can be assigned to the Morganella morganii MORGANII species Morganella morganii.

C76369 MYCOBACTERIUM Any bacteria that is not assigned to the species level Mycobacterium but can be assigned to the Mycobacterium genus level.

C86533 MYCOBACTERIUM MYCOBACTERI Any bacterial organism that can be assigned to the Mycobacterium abscessus ABSCESSUS UM CHELONAE species Mycobacterium abscessus. SUBSP. ABSCESSUS

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 234 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C85491 - MICROORG - Microorganism Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C85544 MYCOBACTERIUM Any bacterial organism that can be assigned to the Mycobacterium africanum AFRICANUM species Mycobacterium africanum.

C86535 MYCOBACTERIUM AVIUM Any bacterial organism that can be assigned to the Mycobacterium avium species Mycobacterium avium.

C76368 MYCOBACTERIUM AVIUM A non-taxonomic grouping of bacteria assigned to and Mycobacterium avium complex COMPLEX including at least three related subspecies from the Mycobacterium avium species.

C86536 MYCOBACTERIUM MYCOBACTERI Any bacterial organism that can be assigned to the Mycobacterium chelonae CHELONAE UM CHELONAE species Mycobacterium chelonae. SUBSP. CHELONAE

C86537 MYCOBACTERIUM Any bacterial organism that can be assigned to the Mycobacterium flavescens FLAVESCENS species Mycobacterium flavescens.

C86538 MYCOBACTERIUM Any bacterial organism that can be assigned to the Mycobacterium fortuitum FORTUITUM species Mycobacterium fortuitum.

C86539 MYCOBACTERIUM A non-taxonomic grouping of bacteria assigned to and Mycobacterium fortuitum Complex FORTUITUM COMPLEX including related species from the Mycobacterium genus.

C86540 MYCOBACTERIUM GASTRI Any bacterial organism that can be assigned to the Mycobacterium gastri species Mycobacterium gastri.

C86541 MYCOBACTERIUM MYCOBACTERI Any bacterial organism that can be assigned to the Mycobacterium gordonae GORDONAE UM AQUAE species Mycobacterium gordonae.

C86542 MYCOBACTERIUM Any bacterial organism that can be assigned to the Mycobacterium haemophilum HAEMOPHILUM species Mycobacterium haemophilum.

C91843 MYCOBACTERIUM Any bacterial organism that can be assigned to the Mycobacterium intracellulare INTRACELLULARE species Mycobacterium intracellulare.

C85543 MYCOBACTERIUM Any bacterial organism that can be assigned to the Mycobacterium kansasii KANSASII species Mycobacterium kansasii.

C86544 MYCOBACTERIUM Any bacterial organism that can be assigned to the Mycobacterium leprae LEPRAE species Mycobacterium leprae.

C86545 MYCOBACTERIUM MYCOBACTERI Any bacterial organism that can be assigned to the Mycobacterium marinum MARINUM UM BALNEI species Mycobacterium marinum.

C86546 MYCOBACTERIUM Any bacterial organism that can be assigned to the Mycobacterium peregrinum PEREGRINUM species Mycobacterium peregrinum.

C86547 MYCOBACTERIUM Any bacterial organism that can be assigned to the Mycobacterium scrofulaceum SCROFULACEUM species Mycobacterium scrofulaceum.

C86548 MYCOBACTERIUM SIMIAE MYCOBACTERI Any bacterial organism that can be assigned to the Mycobacterium simiae UM HABANA species Mycobacterium simiae.

C86590 MYCOBACTERIUM Any bacterial organism that can be assigned to the Mycobacterium smegmatis SMEGMATIS species Mycobacterium smegmatis.

C86591 MYCOBACTERIUM Any bacterial organism that can be assigned to the Mycobacterium szulgai SZULGAI species Mycobacterium szulgai.

C86592 MYCOBACTERIUM Any bacterial organism that can be assigned to the Mycobacterium terrae TERRAE species Mycobacterium terrae.

C86593 MYCOBACTERIUM Any bacterial organism that can be assigned to the Mycobacterium thermoresistibile THERMORESISTIBILE species Mycobacterium thermoresistibile.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 235 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C85491 - MICROORG - Microorganism Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C76370 MYCOBACTERIUM Any bacterial organism that can be assigned to the Mycobacterium tuberculosis TUBERCULOSIS species Mycobacterium tuberculosis.

C86594 MYCOBACTERIUM A non-taxonomic grouping of bacteria assigned to and Mycobacterium tuberculosis TUBERCULOSIS COMPLEX including related species from the Mycobacterium Complex genus.

C86595 MYCOBACTERIUM MYCOBACTERI Any bacterial organism that can be assigned to the Mycobacterium ulcerans ULCERANS UM BURULI species Mycobacterium ulcerans.

C73540 MYCOPLASMA Any bacteria that is not assigned to the species level Mycoplasma but can be assigned to the Mycoplasma genus level.

C86597 MYCOPLASMA HOMINIS Any bacterial organism that can be assigned to the Mycoplasma hominis species Mycoplasma hominis.

C86598 MYCOPLASMA ORALE Any bacterial organism that can be assigned to the Mycoplasma orale species Mycoplasma orale.

C86599 MYCOPLASMA Any bacterial organism that can be assigned to the Mycoplasma pneumoniae PNEUMONIAE species Mycoplasma pneumoniae.

C86953 MYROIDES Any bacteria that is not assigned to the species level Myroides but can be assigned to the Myroides genus level.

C86954 MYROIDES ODORATUS FLAVOBACTER Any bacterial organism that can be assigned to the Myroides odoratus IUM species Myroides odoratus. ODORATUM

C76371 NEISSERIA Any bacteria that is not assigned to the species level Neisseria but can be assigned to the Neisseria genus level.

C86600 NEISSERIA CANIS Any bacterial organism that can be assigned to the Neisseria canis species Neisseria canis.

C86601 NEISSERIA CINEREA MICROCOCCU Any bacterial organism that can be assigned to the Neisseria cinerea S CINEREUS species Neisseria cinerea.

C86602 NEISSERIA FLAVESCENS Any bacterial organism that can be assigned to the Neisseria flavescens species Neisseria flavescens.

C86603 NEISSERIA Any bacterial organism that can be assigned to the Neisseria gonorrhoeae GONORRHOEAE species Neisseria gonorrhoeae.

C86604 NEISSERIA LACTAMICA Any bacterial organism that can be assigned to the Neisseria lactamica species Neisseria lactamica.

C86605 NEISSERIA MENINGITIDIS BETA-LACTAM Any bacterial organism that can be assigned to the Neisseria meningitidis ASE NEGATIVE species Neisseria meningitidis. NEISSERIA MENINGITIDIS

C86606 NEISSERIA MUCOSA Any bacterial organism that can be assigned to the Neisseria mucosa species Neisseria mucosa.

C86607 NEISSERIA Any bacterial organism that can be assigned to the Neisseria polysaccharea POLYSACCHAREA species Neisseria polysaccharea.

C86608 NEISSERIA SICCA Any bacterial organism that can be assigned to the Neisseria sicca species Neisseria sicca.

C86609 NEISSERIA SUBFLAVA Any bacterial organism that can be assigned to the Neisseria subflava species Neisseria subflava.

C86610 NEISSERIA WEAVERII CDC GROUP Any bacterial organism that can be assigned to the Neisseria weaverii M-5 species Neisseria weaverii.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 236 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C85491 - MICROORG - Microorganism Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C76372 NOCARDIA Any bacteria that is not assigned to the species level Nocardia but can be assigned to the Nocardia genus level.

C86611 NOCARDIA ASTEROIDES Any bacterial organism that can be assigned to the Nocardia asteroides species Nocardia asteroides.

C86612 NOCARDIA ASTEROIDES A non-taxonomic grouping of bacteria assigned to and Nocardia asteroides Complex COMPLEX including at least four related species from the Nocardia genus.

C86613 NOCARDIA BRASILIENSIS Any bacterial organism that can be assigned to the Nocardia brasiliensis species Nocardia brasiliensis.

C86614 NOCARDIA DASSONVILLEI Any bacterial organism that can be assigned to the Nocardia dassonvillei species Nocardia dassonvillei.

C86615 NOCARDIA FARCINICA Any bacterial organism that can be assigned to the Nocardia farcinica species Nocardia farcinica.

C86616 NOCARDIA NOVA Any bacterial organism that can be assigned to the Nocardia nova species Nocardia nova.

C86617 NOCARDIA NOCARDIA Any bacterial organism that can be assigned to the Nocardia otitidiscaviarum OTITIDISCAVIARUM CAVIAE species Nocardia otitidiscaviarum.

C86618 NON-FERMENTATIVE NON-FERMENT Any rod-shaped, anaerobic bacteria that cannot convert Non-Fermentative Gram Negative GRAM-NEGATIVE ATIVE carbohydrates into acids and alcohols and has a cell Bacillus BACILLUS GRAM-NEGATI wall that contains low levels of peptidoglycan and VE ROD stains pink with the Gram staining technique.

C86619 OCHROBACTRUM Any bacteria that is not assigned to the species level Ochrobactrum but can be assigned to the Ochrobactrum genus level.

C86620 OCHROBACTRUM ACHROMOBAC Any bacterial organism that can be assigned to the Ochrobactrum anthropi ANTHROPI TER SUBSP. species Ochrobactrum anthropi. BIOTYPE 1

C86621 OCHROBACTRUM Any bacterial organism that can be assigned to the Ochrobactrum intermedium INTERMEDIUM species Ochrobactrum intermedium.

C86622 OERSKOVIA Any bacteria that is not assigned to the species level Oerskovia but can be assigned to the Oerskovia genus level.

C86623 OERSKOVIA TURBATA Any bacterial organism that can be assigned to the Oerskovia turbata species Oerskovia turbata.

C86624 OLIGELLA Any bacteria that is not assigned to the species level Oligella but can be assigned to the Oligella genus level.

C86625 OLIGELLA UREOLYTICA CDC GROUP Any bacterial organism that can be assigned to the Oligella ureolytica IVE species Oligella ureolytica.

C86626 OLIGELLA URETHRALIS CDC GROUP Any bacterial organism that can be assigned to the Oligella urethralis M-4 species Oligella urethralis.

C86627 OLSENELLA Any bacteria that is not assigned to the species level Olsenella but can be assigned to the Olsenella genus level.

C86628 OLSENELLA ULI LACTOBACILL Any bacterial organism that can be assigned to the Olsenella uli US ULI species Olsenella uli.

C86629 PANDORAEA Any bacteria that is not assigned to the species level Pandoraea but can be assigned to the Pandoraea genus level.

C86630 PANDORAEA PNOMENUSA Any bacterial organism that can be assigned to the Pandoraea pnomenusa species Pandoraea pnomenusa.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 237 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C85491 - MICROORG - Microorganism Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C86631 PANTOEA Any bacteria that is not assigned to the species level Pantoea but can be assigned to the Pantoea genus level.

C86632 PANTOEA AGGLOMERANS ENTEROBACTE Any bacterial organism that can be assigned to the Pantoea agglomerans R species Pantoea agglomerans. AGGLOMERAN S

C86633 PARABACTEROIDES Any bacteria that is not assigned to the species level Parabacteroides but can be assigned to the Parabacteroides genus level.

C86634 PARABACTEROIDES BACTEROIDES Any bacterial organism that can be assigned to the Parabacteroides distasonis DISTASONIS DISTASONIS species Parabacteroides distasonis.

C86635 PARABACTEROIDES BACTEROIDES Any bacterial organism that can be assigned to the Parabacteroides merdae MERDAE MERDAE; species Parabacteroides merdae. BACTEROIDES FRAGILIS T4-1

C86900 PARVIMONAS Any bacteria that is not assigned to the species level Parvimonas but can be assigned to the Parvimonas genus level.

C86901 PARVIMONAS MICRA PEPTOSTREPT Any bacterial organism that can be assigned to the Parvimonas micra OCOCCUS species Parvimonas micra. MICROS; MICROMONAS MICROS

C86636 PASTEURELLA Any bacteria that is not assigned to the species level Pasteurella but can be assigned to the Pasteurella genus level.

C86637 PASTEURELLA Any bacterial organism that can be assigned to the Pasteurella aerogenes AEROGENES species Pasteurella aerogenes.

C86638 PASTEURELLA BETTYAE CDC GROUP Any bacterial organism that can be assigned to the Pasteurella bettyae HB-5 species Pasteurella bettyae.

C86639 PASTEURELLA CANIS PASTEURELLA Any bacterial organism that can be assigned to the Pasteurella canis MULTOCIDA species Pasteurella canis. BIOTYPE 6

C76373 PASTEURELLA PASTEURELLA Any bacterial organism that can be assigned to the Pasteurella multocida MULTOCIDA SEPTICA species Pasteurella multocida.

C86640 PASTEURELLA Any bacterial organism that can be assigned to the Pasteurella pneumotropica PNEUMOTROPICA species Pasteurella pneumotropica.

C86641 PEDIOCOCCUS Any bacteria that is not assigned to the species level Pediococcus but can be assigned to the Pediococcus genus level.

C86642 PEPTOCOCCUS Any bacteria that is not assigned to the species level Peptococcus but can be assigned to the Peptococcus genus level.

C86643 PEPTOCOCCUS NIGER MICROCOCCU Any bacterial organism that can be assigned to the Peptococcus niger S NIGER species Peptococcus niger.

C86902 PEPTONIPHILUS Any bacteria that is not assigned to the species level Peptoniphilus but can be assigned to the Peptoniphilus genus level.

C86903 PEPTONIPHILUS PEPTOCOCCUS Any bacterial organism that can be assigned to the Peptoniphilus asaccharolyticus ASACCHAROLYTICUS ASACCHAROL species Peptoniphilus asaccharolyticus. YTICUS; PEPTOSTREPT OCOCCUS ASACCHAROL YTICUS

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 238 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C85491 - MICROORG - Microorganism Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C86904 PEPTONIPHILUS PEPTOSTREPT Any bacterial organism that can be assigned to the Peptoniphilus indolicus INDOLICUS OCOCCUS species Peptoniphilus indolicus. INDOLICUS

C86644 PEPTOSTREPTOCOCCUS Any bacteria that is not assigned to the species level Peptostreptococcus but can be assigned to the Peptostreptococcus genus level.

C86645 PEPTOSTREPTOCOCCUS Any bacterial organism that can be assigned to the Peptostreptococcus anaerobius ANAEROBIUS species Peptostreptococcus anaerobius.

C86646 PHOTOBACTERIUM Any bacteria that is not assigned to the species level Photobacterium but can be assigned to the Photobacterium genus level.

C86647 PHOTOBACTERIUM VIBRIO Any bacterial organism that can be assigned to the Photobacterium damselae DAMSELAE DAMSELA; species Photobacterium damselae. CDC GROUP EF-5, PHOTOBACTER IUM DAMSELAE SUBSP. DAMSELAE

C86648 PHOTORHABDUS Any bacteria that is not assigned to the species level Photorhabdus but can be assigned to the Photorhabdus genus level.

C86649 PHOTORHABDUS Any bacterial organism that can be assigned to the Photorhabdus luminescens LUMINESCENS species Photorhabdus luminescens.

C86650 PLANOCOCCUS Any bacteria that is not assigned to the species level Planococcus but can be assigned to the Planococcus genus level.

C86651 PLESIOMONAS Any bacteria that is not assigned to the species level Plesiomonas but can be assigned to the Plesiomonas genus level.

C86652 PLESIOMONAS AEROMONAS Any bacterial organism that can be assigned to the Plesiomonas shigelloides SHIGELLOIDES SHIGELLOIDES species Plesiomonas shigelloides.

C86653 PORPHYROMONAS Any bacteria that is not assigned to the species level Porphyromonas but can be assigned to the Porphyromonas genus level.

C86654 PORPHYROMONAS BACTEROIDES Any bacterial organism that can be assigned to the Porphyromonas asaccharolytica ASACCHAROLYTICA ASACCHAROL species Porphyromonas asaccharolytica. YTICUS

C86655 PORPHYROMONAS Any bacterial organism that can be assigned to the Porphyromonas catoniae CATONIAE species Porphyromonas catoniae.

C86656 PORPHYROMONAS BACTEROIDES Any bacterial organism that can be assigned to the Porphyromonas endodontalis ENDODONTALIS ENDODONTALI species Porphyromonas endodontalis. S

C86657 PORPHYROMONAS BACTEROIDES Any bacterial organism that can be assigned to the Porphyromonas gingivalis GINGIVALIS GINGIVALIS species Porphyromonas gingivalis.

C86658 PORPHYROMONAS LEVII BACTEROIDES Any bacterial organism that can be assigned to the Porphyromonas levii LEVII; species Porphyromonas levii. BACTEROIDES MELANINOGE NICUS SUBSP. LEVII

C86659 PORPHYROMONAS Any bacterial organism that can be assigned to the Porphyromonas somerae SOMERAE species Porphyromonas somerae.

C86660 PREVOTELLA Any bacteria that is not assigned to the species level Prevotella but can be assigned to the Prevotella genus level.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 239 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C85491 - MICROORG - Microorganism Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C86661 PREVOTELLA BIVIA BACTEROIDES Any bacterial organism that can be assigned to the Prevotella bivia BIVIA species Prevotella bivia.

C86662 PREVOTELLA BREVIS BACTEROIDES Any bacterial organism that can be assigned to the Prevotella brevis RUMINICOLA species Prevotella brevis. SUBSP. BREVUS; BACTEROIDES RUMINICOLA SUBSP. BREVIS

C86663 PREVOTELLA BUCCAE BACTEROIDES Any bacterial organism that can be assigned to the Prevotella buccae BUCCAE species Prevotella buccae.

C86664 PREVOTELLA BUCCALIS Any bacterial organism that can be assigned to the Prevotella buccalis species Prevotella buccalis.

C86665 PREVOTELLA CORPORIS Any bacterial organism that can be assigned to the Prevotella corporis species Prevotella corporis.

C86666 PREVOTELLA DENTALIS Any bacterial organism that can be assigned to the Prevotella dentalis species Prevotella dentalis.

C86667 PREVOTELLA DENTICOLA BACTEROIDES Any bacterial organism that can be assigned to the Prevotella denticola DENTICOLA species Prevotella denticola.

C86668 PREVOTELLA DISIENS BACTEROIDES Any bacterial organism that can be assigned to the Prevotella disiens DISIENS species Prevotella disiens.

C86669 PREVOTELLA BACTEROIDES Any bacterial organism that can be assigned to the Prevotella heparinolytica HEPARINOLYTICA HEPARINOLYTI species Prevotella heparinolytica. CUS

C86670 PREVOTELLA INTERMEDIA BACTEROIDES Any bacterial organism that can be assigned to the Prevotella intermedia INTERMEDIA species Prevotella intermedia.

C86671 PREVOTELLA A non-taxonomic grouping of bacteria assigned to the Prevotella intermedia/nigrescens INTERMEDIA/NIGRESCENS Prevotella genus that include the P. intermedia and P. Group GROUP nigrescens species.

C86672 PREVOTELLA LOESCHEII Any bacterial organism that can be assigned to the Prevotella loescheii species Prevotella loescheii.

C86673 PREVOTELLA BACTEROIDES Any bacterial organism that can be assigned to the Prevotella melaninogenica MELANINOGENICA MELANINOGE species Prevotella melaninogenica. NICUS

C86674 PREVOTELLA NIGRESCENS Any bacterial organism that can be assigned to the Prevotella nigrescens species Prevotella nigrescens.

C86675 PREVOTELLA ORALIS BACTEROIDES Any bacterial organism that can be assigned to the Prevotella oralis ORALIS species Prevotella oralis.

C86676 PREVOTELLA ORIS BACTEROIDES Any bacterial organism that can be assigned to the Prevotella oris ORIS species Prevotella oris.

C86677 PREVOTELLA BACTEROIDES Any bacterial organism that can be assigned to the Prevotella ruminicola RUMINICOLA RUMINICOLA species Prevotella ruminicola.

C86678 PREVOTELLA TANNERAE Any bacterial organism that can be assigned to the Prevotella tannerae species Prevotella tannerae.

C86679 PREVOTELLA VERORALIS Any bacterial organism that can be assigned to the Prevotella veroralis species Prevotella veroralis.

C86013 PROPIONIBACTERIUM Any bacteria that is not assigned to the species level Propionibacterium but can be assigned to the Propionibacterium genus level.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 240 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C85491 - MICROORG - Microorganism Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C14378 PROPIONIBACTERIUM BACILLUS Any bacterial organism that can be assigned to the Propionibacterium acnes ACNES ACNES; species Propionibacterium acnes. CORYNEBACTE RIUM ACNES; CORYNEBACTE RIUM PARVUM; C. PARVUM; CPARV

C86681 PROPIONIBACTERIUM Any bacterial organism that can be assigned to the Propionibacterium avidum AVIDUM species Propionibacterium avidum.

C86682 PROPIONIBACTERIUM CORYNEBACTE Any bacterial organism that can be assigned to the Propionibacterium granulosum GRANULOSUM RIUM species Propionibacterium granulosum. GRANULOSUM

C86683 PROPIONIBACTERIUM ACTINOMYCES Any bacterial organism that can be assigned to the Propionibacterium propionicum PROPIONICUM PROPIONICUS species Propionibacterium propionicum.

C76374 PROTEUS Any bacteria that is not assigned to the species level Proteus but can be assigned to the Proteus genus level.

C86684 PROTEUS HAUSERI Any bacterial organism that can be assigned to the Proteus hauseri species Proteus hauseri.

C84582 PROTEUS INCONSTANS PROVIDENCIA Any bacterial organism that can be assigned to the Proteus inconstans INCONSTANS species Proteus inconstans.

C86019 PROTEUS MIRABILIS Any bacterial organism that can be assigned to the Proteus mirabilis species Proteus mirabilis.

C86687 PROTEUS MYXOFACIENS Any bacterial organism that can be assigned to the Proteus myxofaciens species Proteus myxofaciens.

C86688 PROTEUS PENNERI INDOLE Any bacterial organism that can be assigned to the Proteus penneri NEGATIVE species Proteus penneri. PROTEUS VULGARIS

C85250 PROTEUS VULGARIS Any bacterial organism that can be assigned to the Proteus vulgaris species Proteus vulgaris.

C86690 PROVIDENCIA Any bacteria that is not assigned to the species level Providencia but can be assigned to the Providencia genus level.

C86691 PROVIDENCIA Any bacterial organism that can be assigned to the Providencia alcalifaciens ALCALIFACIENS species Providencia alcalifaciens.

C86692 PROVIDENCIA Any bacterial organism that can be assigned to the Providencia heimbachae HEIMBACHAE species Providencia heimbachae.

C86693 PROVIDENCIA RETTGERI Any bacterial organism that can be assigned to the Providencia rettgeri species Providencia rettgeri.

C86694 PROVIDENCIA PROVIDENCIA Any bacterial organism that can be assigned to the Providencia rustigianii RUSTIGIANII ALCALIFACIEN species Providencia rustigianii. S BIOGROUP 3

C86695 PROVIDENCIA STUARTII Any bacterial organism that can be assigned to the Providencia stuartii species Providencia stuartii.

C76375 PSEUDOMONAS Any bacteria that is not assigned to the species level Pseudomonas but can be assigned to the Pseudomonas genus level.

C86696 PSEUDOMONAS Any bacterial organism that can be assigned to the Pseudomonas aeruginosa AERUGINOSA species Pseudomonas aeruginosa.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 241 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C85491 - MICROORG - Microorganism Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C86697 PSEUDOMONAS Any bacterial organism that can be assigned to the Pseudomonas alcaligenes ALCALIGENES species Pseudomonas alcaligenes.

C86699 PSEUDOMONAS Any bacterial organism that can be assigned to the Pseudomonas chlororaphis CHLORORAPHIS species Pseudomonas chlororaphis.

C86962 PSEUDOMONAS A non-taxonomic grouping of bacteria assigned to the Pseudomonas fluorescens/putida FLUORESCENS/PUTIDA Pseudomonas genus that include the P. fluorescens and Group GROUP P. putida species.

C86701 PSEUDOMONAS LUTEOLA CHRYSEOMON Any bacterial organism that can be assigned to the Pseudomonas luteola AS LUTEOLA species Pseudomonas luteola.

C86702 PSEUDOMONAS CDC GROUP Any bacterial organism that can be assigned to the Pseudomonas mendocina MENDOCINA VB-2 species Pseudomonas mendocina.

C86703 PSEUDOMONAS MOSSELII Any bacterial organism that can be assigned to the Pseudomonas mosselii species Pseudomonas mosselii.

C76319 PSEUDOMONAS FLAVIMONAS Any bacterial organism that can be assigned to the Pseudomonas oryzihabitans ORYZIHABITANS ORYZIHABITA species Pseudomonas oryzihabitans. NS

C86704 PSEUDOMONAS PSEUDOMONA Any bacterial organism that can be assigned to the Pseudomonas pseudoalcaligenes PSEUDOALCALIGENES S species Pseudomonas pseudoalcaligenes. ALCALIGENES BIOTYPE B

C86705 PSEUDOMONAS PUTIDA Any bacterial organism that can be assigned to the Pseudomonas putida species Pseudomonas putida.

C86706 PSEUDOMONAS STUTZERI PSEUDOMONA Any bacterial organism that can be assigned to the Pseudomonas stutzeri S GROUP VB-1 species Pseudomonas stutzeri.

C86707 PSYCHROBACTER Any bacteria that is not assigned to the species level Psychrobacter but can be assigned to the Psychrobacter genus level.

C86708 PSYCHROBACTER Any bacterial organism that can be assigned to the Psychrobacter immobilis IMMOBILIS species Psychrobacter immobilis.

C86709 PSYCHROBACTER MORAXELLA Any bacterial organism that can be assigned to the Psychrobacter phenylpyruvicus PHENYLPYRUVICUS PHENYLPYRU species Psychrobacter phenylpyruvicus. VICA; CDC GROUP M-2

C86710 RAHNELLA Any bacteria that is not assigned to the species level Rahnella but can be assigned to the Rahnella genus level.

C86711 RAHNELLA AQUATILIS Any bacterial organism that can be assigned to the Rahnella aquatilis species Rahnella aquatilis.

C86712 RALSTONIA Any bacteria that is not assigned to the species level Ralstonia but can be assigned to the Ralstonia genus level.

C86713 RALSTONIA PICKETTII BURKHOLDERI Any bacterial organism that can be assigned to the Ralstonia pickettii A PICKETTII; species Ralstonia pickettii. PSEUDOMONA S PICKETTII

C86714 RAOULTELLA Any bacteria that is not assigned to the species level Raoultella but can be assigned to the Raoultella genus level.

C86715 RAOULTELLA KLEBSIELLA Any bacterial organism that can be assigned to the Raoultella ornithinolytica ORNITHINOLYTICA ORNITHINOLY species Raoultella ornithinolytica. TICA

C86716 RAOULTELLA Any bacterial organism that can be assigned to the Raoultella planticola PLANTICOLA species Raoultella planticola.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 242 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C85491 - MICROORG - Microorganism Codelist extensible: Yes

CDISC NCI CodeCDISC Submission Value SynonymCDISC DefinitionNCI Preferred Term

C86717 RAOULTELLA TERRIGENAKLEBSIELLA Any bacterial organism that can be assigned to the Raoultella terrigena TERRIGENA species Raoultella terrigena.

C86718 RHIZOBIUMAny bacteria that is not assigned to the species level Rhizobium but can be assigned to the Rhizobium genus level.

C76378 RHODOCOCCUSAny bacteria that is not assigned to the species level Rhodococcus but can be assigned to the Rhodococcus genus level.

C86719 RHODOCOCCUS EQUICORYNEBACTE Any bacterial organism that can be assigned to the Rhodococcus equi RIUM EQUI species Rhodococcus equi.

C76379 RICKETTSIAAny bacteria that is not assigned to the species level Rickettsia but can be assigned to the Rickettsia genus level.

C86720 RICKETTSIA AFRICAEAny bacterial organism that can be assigned to the Rickettsia africae species Rickettsia africae.

C86721 RICKETTSIA FELISAny bacterial organism that can be assigned to the Rickettsia felis species Rickettsia felis.

C86722 RICKETTSIA JAPONICAAny bacterial organism that can be assigned to the Rickettsia japonica species Rickettsia japonica.

C86723 RICKETTSIA PROWAZEKIIAny bacterial organism that can be assigned to the Rickettsia prowazekii species Rickettsia prowazekii.

C86724 RICKETTSIA RICKETTSIIAny bacterial organism that can be assigned to the Rickettsia rickettsii species Rickettsia rickettsii.

C86725 RICKETTSIA TYPHIAny bacterial organism that can be assigned to the Rickettsia typhi species Rickettsia typhi.

C86726 ROSEOMONASAny bacteria that is not assigned to the species level Roseomonas but can be assigned to the Roseomonas genus level.

C86727 ROTHIAAny bacteria that is not assigned to the species level Rothia but can be assigned to the Rothia genus level.

C86728 ROTHIA DENTOCARIOSANOCARDIA Any bacterial organism that can be assigned to the Rothia dentocariosa DENTOCARIOS species Rothia dentocariosa. A

C76382ROTHIA MUCILAGINOSASTOMATOCOC Any bacterial organism that can be assigned to the Rothia mucilaginosa CUS species Rothia mucilaginosa. MUCILAGINOS US

C86729 RUMINOCOCCUSAny bacteria that is not assigned to the species level Ruminococcus but can be assigned to the Ruminococcus genus level.

C86730 RUMINOCOCCUS PEPTOSTREPT Any bacterial organism that can be assigned to the Ruminococcus productus PRODUCTUS OCOCCUS species Ruminococcus productus. PRODUCTUS

C76380SALMONELLASALMONELLA Any bacteria that is not assigned to the species level Salmonella SEROGROUP D but can be assigned to the Salmonella genus level. (NOT S. TYPHI)

C91842SALMONELLA BONGORIAny bacterial organism that can be assigned to the Salmonella bongori species Salmonella bongori.

C86731 SALMONELLA ENTERICAAny bacterial organism that can be assigned to the Salmonella enterica species Salmonella enterica.

C86910 SALMONELLA ENTERICA Any bacterial organism that can be assigned to the SUBSP. ARIZONAE species Salmonella enterica subspecies arizonae.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 243 of 431 -A> CDISC Controlled Terminology SDTM - 2012-03-23 C85491 - MICROORG - Microorganism Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C91844 SALMONELLA ENTERICA Any bacterial organism that can be assigned to the Salmonella enterica subsp diarizonae SUBSP. DIARIZONAE species Salmonella enterica subspecies diarizonae.

C86913 SALMONELLA ENTERICA Any bacterial organism that can be assigned to the Salmonella enterica subsp enterica SUBSP. ENTERICA species Salmonella enterica subspecies enterica.

C91845 SALMONELLA ENTERICA Any bacterial organism that can be assigned to the Salmonella enterica subsp houtenae SUBSP. HOUTENAE species Salmonella enterica subspecies houtenae.

C91846 SALMONELLA ENTERICA Any bacterial organism that can be assigned to the Salmonella enterica subsp indica SUBSP. INDICA species Salmonella enterica subspecies indica.

C91847 SALMONELLA ENTERICA Any bacterial organism that can be assigned to the Salmonella enterica subsp salamae SUBSP. SALAMAE species Salmonella enterica subspecies salamae.

C86915 SALMONELLA SEROTYPE Any bacterial organism that can be assigned to the Salmonella Serotype Choleraesuis CHOLERAESUIS genus Salmonella with serotype Choleraesuis.

C86918 SALMONELLA SEROTYPE Any bacterial organism that can be assigned to the Salmonella Serotype Dublin DUBLIN genus Salmonella with serotype Dublin.

C86919 SALMONELLA SEROTYPE Any bacterial organism that can be assigned to the Salmonella Serotype Enteritidis ENTERITIDIS genus Salmonella with serotype Enteritidis.

C86921 SALMONELLA SEROTYPE Any bacterial organism that can be assigned to the Salmonella Serotype Newport NEWPORT genus Salmonella with serotype Newport.

C86922 SALMONELLA SEROTYPE Any bacterial organism that can be assigned to the Salmonella Serotype Paratyphi A PARATYPHI A genus Salmonella with serotype Paratyphi A.

C86924 SALMONELLA SEROTYPE Any bacterial organism that can be assigned to the Salmonella Serotype Paratyphi B PARATYPHI B genus Salmonella with serotype Paratyphi B.

C86925 SALMONELLA SEROTYPE Any bacterial organism that can be assigned to the Salmonella Serotype Paratyphi C PARATYPHI C genus Salmonella with serotype Paratyphi C.

C86926 SALMONELLA SEROTYPE Any bacterial organism that can be assigned to the Salmonella Serotype Typhi TYPHI genus Salmonella with serotype Typhi.

C86927 SALMONELLA SEROTYPE Any bacterial organism that can be assigned to the Salmonella Serotype Typhimurium TYPHIMURIUM genus Salmonella with serotype Typhimurium.

C86732 SELENOMONAS Any bacteria that is not assigned to the species level Selenomonas but can be assigned to the Selenomonas genus level.

C86733 SELENOMONAS NOXIA Any bacterial organism that can be assigned to the Selenomonas noxia species Selenomonas noxia.

C86734 SELENOMONAS Any bacterial organism that can be assigned to the Selenomonas sputigena SPUTIGENA species Selenomonas sputigena.

C86010 SERRATIA SERRATIA Any bacteria that is not assigned to the species level Serratia but can be assigned to the Serratia genus level.

C86736 SERRATIA FICARIA Any bacterial organism that can be assigned to the Serratia ficaria species Serratia ficaria.

C86737 SERRATIA FONTICOLA Any bacterial organism that can be assigned to the Serratia fonticola species Serratia fonticola.

C86738 SERRATIA LIQUEFACIENS ENTEROBACTE Any bacterial organism that can be assigned to the Serratia liquefaciens R species Serratia liquefaciens. LIQUEFACIENS

C14272 SERRATIA MARCESCENS S. Any bacterial organism that can be assigned to the Serratia marcescens MARCESCENS species Serratia marcescens.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 244 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C85491 - MICROORG - Microorganism Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C86739 SERRATIA ODORIFERA Any bacterial organism that can be assigned to the Serratia odorifera species Serratia odorifera.

C86740 SERRATIA PLYMUTHICA Any bacterial organism that can be assigned to the Serratia plymuthica species Serratia plymuthica.

C86741 SERRATIA RUBIDAEA SERRATIA Any bacterial organism that can be assigned to the Serratia rubidaea MARINORUBR species Serratia rubidaea. A

C86742 SHEWANELLA Any bacteria that is not assigned to the species level Shewanella but can be assigned to the Shewanella genus level.

C86743 SHEWANELLA ALTEROMONA Any bacterial organism that can be assigned to the Shewanella putrefaciens PUTREFACIENS S species Shewanella putrefaciens. PUTREFACIENS ; PSEUDOMONA S PUTREFACIENS

C76381 SHIGELLA Any bacteria that is not assigned to the species level Shigella but can be assigned to the Shigella genus level.

C86744 SHIGELLA BOYDII SHIGELLA Any bacterial organism that can be assigned to the Shigella boydii BIOGROUP C species Shigella boydii.

C86745 SHIGELLA DYSENTERIAE SHIGELLA Any bacterial organism that can be assigned to the Shigella dysenteriae BIOGROUP A species Shigella dysenteriae.

C86746 SHIGELLA FLEXNERI SHIGELLA Any bacterial organism that can be assigned to the Shigella flexneri BIOGROUP B species Shigella flexneri.

C86747 SHIGELLA SONNEI SHIGELLA Any bacterial organism that can be assigned to the Shigella sonnei BIOGROUP D species Shigella sonnei.

C86957 SPHINGOBACTERIUM Any bacteria that is not assigned to the species level Sphingobacterium but can be assigned to the Sphingobacterium genus level.

C86958 SPHINGOBACTERIUM FLAVOBACTER Any bacterial organism that can be assigned to the Sphingobacterium mizutaii MIZUTAII IUM MIZUTAE species Sphingobacterium mizutaii.

C86959 SPHINGOBACTERIUM CDC GROUP Any bacterial organism that can be assigned to the Sphingobacterium multivorum MULTIVORUM IIK-2 species Sphingobacterium multivorum.

C86960 SPHINGOBACTERIUM CDC GROUP Any bacterial organism that can be assigned to the Sphingobacterium spiritivorum SPIRITIVORUM IIK-3 species Sphingobacterium spiritivorum.

C86961 SPHINGOBACTERIUM FLAVOBACTER Any bacterial organism that can be assigned to the Sphingobacterium thalpophilum THALPOPHILUM IUM species Sphingobacterium thalpophilum. THALPOPHILU M

C86748 SPHINGOMONAS Any bacteria that is not assigned to the species level Sphingomonas but can be assigned to the Sphingomonas genus level.

C86749 SPHINGOMONAS CDC GROUP Any bacterial organism that can be assigned to the Sphingomonas paucimobilis PAUCIMOBILIS IIK-1; species Sphingomonas paucimobilis. PSEUDOMONA S PAUCIMOBILIS

C62583 STAPHYLOCOCCUS Any bacteria that is not assigned to the species level Staphylococcus but can be assigned to the Staphylococcus genus level.

C86750 STAPHYLOCOCCUS Any bacterial organism that can be assigned to the Staphylococcus arlettae ARLETTAE species Staphylococcus arlettae.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 245 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C85491 - MICROORG - Microorganism Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C50921 STAPHYLOCOCCUS STAPH. Any bacterial organism that can be assigned to the Staphylococcus aureus AUREUS AUREUS species Staphylococcus aureus.

C86751 STAPHYLOCOCCUS Any bacterial organism that can be assigned to the Staphylococcus auricularis AURICULARIS species Staphylococcus auricularis.

C86752 STAPHYLOCOCCUS Any bacterial organism that can be assigned to the Staphylococcus capitis CAPITIS species Staphylococcus capitis.

C86753 STAPHYLOCOCCUS Any bacterial organism that can be assigned to the Staphylococcus caprae CAPRAE species Staphylococcus caprae.

C86754 STAPHYLOCOCCUS Any bacterial organism that can be assigned to the Staphylococcus carnosus CARNOSUS species Staphylococcus carnosus.

C86755 STAPHYLOCOCCUS Any bacterial organism that can be assigned to the Staphylococcus chromogenes CHROMOGENES species Staphylococcus chromogenes.

C86756 STAPHYLOCOCCUS Any bacterial organism that can be assigned to the Staphylococcus cohnii COHNII species Staphylococcus cohnii.

C86757 STAPHYLOCOCCUS STAPHYLOCOC Any bacterial organism that can be assigned to the Staphylococcus epidermidis EPIDERMIDIS CUS ALBUS species Staphylococcus epidermidis.

C86758 STAPHYLOCOCCUS Any bacterial organism that can be assigned to the Staphylococcus equorum EQUORUM species Staphylococcus equorum.

C86759 STAPHYLOCOCCUS FELIS Any bacterial organism that can be assigned to the Staphylococcus felis species Staphylococcus felis.

C86760 STAPHYLOCOCCUS Any bacterial organism that can be assigned to the Staphylococcus gallinarum GALLINARUM species Staphylococcus gallinarum.

C86761 STAPHYLOCOCCUS STAPH. Any bacterial organism that can be assigned to the Staphylococcus haemolyticus HAEMOLYTICUS HAEMOLYTICU species Staphylococcus haemolyticus. S

C86762 STAPHYLOCOCCUS COAGULASE Any bacterial organism that can be assigned to the Staphylococcus hominis HOMINIS NEGATIVE species Staphylococcus hominis. STAPHYLOCOC CUS HOMINIS

C86763 STAPHYLOCOCCUS Any bacterial organism that can be assigned to the Staphylococcus hyicus HYICUS species Staphylococcus hyicus.

C86764 STAPHYLOCOCCUS Any bacterial organism that can be assigned to the Staphylococcus intermedius INTERMEDIUS species Staphylococcus intermedius.

C86765 STAPHYLOCOCCUS Any bacterial organism that can be assigned to the Staphylococcus kloosii KLOOSII species Staphylococcus kloosii.

C86766 STAPHYLOCOCCUS Any bacterial organism that can be assigned to the Staphylococcus lentus LENTUS species Staphylococcus lentus.

C86767 STAPHYLOCOCCUS Any bacterial organism that can be assigned to the Staphylococcus lugdunensis LUGDUNENSIS species Staphylococcus lugdunensis.

C86768 STAPHYLOCOCCUS Any bacterial organism that can be assigned to the Staphylococcus pasteuri PASTEURI species Staphylococcus pasteuri.

C86769 STAPHYLOCOCCUS PEPTOCOCCUS Any bacterial organism that can be assigned to the Staphylococcus saccharolyticus SACCHAROLYTICUS SACCHAROLYT species Staphylococcus saccharolyticus. ICUS

C86770 STAPHYLOCOCCUS MICROCOCCU Any bacterial organism that can be assigned to the Staphylococcus saprophyticus SAPROPHYTICUS S SUBGROUP 3 species Staphylococcus saprophyticus.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 246 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C85491 - MICROORG - Microorganism Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C86771 STAPHYLOCOCCUS Any bacterial organism that can be assigned to the Staphylococcus schleiferi SCHLEIFERI species Staphylococcus schleiferi.

C86772 STAPHYLOCOCCUS SCIURI Any bacterial organism that can be assigned to the Staphylococcus sciuri species Staphylococcus sciuri.

C86773 STAPHYLOCOCCUS Any bacterial organism that can be assigned to the Staphylococcus simulans SIMULANS species Staphylococcus simulans.

C86774 STAPHYLOCOCCUS Any bacterial organism that can be assigned to the Staphylococcus warneri WARNERI species Staphylococcus warneri.

C86775 STAPHYLOCOCCUS Any bacterial organism that can be assigned to the Staphylococcus xylosus XYLOSUS species Staphylococcus xylosus.

C86776 STENOTROPHOMONAS STENOTROPHO Any bacteria that is not assigned to the species level Stenotrophomonas MONAS but can be assigned to the Stenotrophomonas genus level.

C76377 STENOTROPHOMONAS PSEUDOMONA Any bacterial organism that can be assigned to the Stenotrophomonas maltophilia MALTOPHILIA S species Stenotrophomonas maltophilia. MALTOPHILIA; XANTHOMONA S MALTOPHILIA

C86777 STREPTOBACILLUS Any bacteria that is not assigned to the species level Streptobacillus but can be assigned to the Streptobacillus genus level.

C86778 STREPTOBACILLUS HAVERHILLIA Any bacterial organism that can be assigned to the Streptobacillus moniliformis MONILIFORMIS MULTIFORMIS species Streptobacillus moniliformis.

C76383 STREPTOCOCCUS STREPTOCOCC Any bacteria that is not assigned to the species level Streptococcus I SP. but can be assigned to the Streptococcus genus level.

C86779 STREPTOCOCCUS Any bacterial organism that can be assigned to the Streptococcus acidominimus ACIDOMINIMUS species Streptococcus acidominimus.

C86780 STREPTOCOCCUS STREPT. GP Any bacterial organism that can be assigned to the Streptococcus agalactiae AGALACTIAE B(AGALACT) species Streptococcus agalactiae.

C86781 STREPTOCOCCUS Any bacterial organism that can be assigned to the Streptococcus alactolyticus ALACTOLYTICUS species Streptococcus alactolyticus.

C86141 STREPTOCOCCUS ALPHA-HEMOL A bacteria that is assigned to the genus Streptococcus Alpha-Hemolytic Streptococcus ALPHA-HEMOLYTIC YTIC that is able to reduce the iron content in hemoglobin in STREPTOCOCC red blood cells, thus producing green-colored colonies US on blood agar plates.

C86782 STREPTOCOCCUS Any bacterial organism that can be assigned to the Streptococcus anginosis ANGINOSIS species Streptococcus anginosis.

C86783 STREPTOCOCCUS A bacteria that belongs to the Anginosus group of the Streptococcus anginosus Group ANGINOSUS GROUP genus Streptococcus.

C86190 STREPTOCOCCUS BETA-HEMOLY A bacteria that is assigned to the genus Streptococcus Beta-Hemolytic Streptococcus BETA-HEMOLYTIC TIC that is able to facilitate the complete rupturing of red STREPTOCOCC blood cells, thus producing wide, clear, zones around US colonies on blood agar plates.

C86784 STREPTOCOCCUS BOVIS Any bacterial organism that can be assigned to the Streptococcus bovis species Streptococcus bovis.

C86785 STREPTOCOCCUS BOVIS A bacteria that belongs to the Bovis group of the genus Streptococcus bovis Group GROUP Streptococcus.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 247 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C85491 - MICROORG - Microorganism Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C86786 STREPTOCOCCUS CANIS STREPTOCOCC Any bacterial organism that can be assigned to the Streptococcus canis US species Streptococcus canis. DYSGALACTIA E

C86787 STREPTOCOCCUS Any bacterial organism that can be assigned to the Streptococcus constellatus CONSTELLATUS species Streptococcus constellatus.

C86788 STREPTOCOCCUS Any bacterial organism that can be assigned to the Streptococcus cristatus CRISTATUS species Streptococcus cristatus.

C91848 STREPTOCOCCUS Any bacterial organism that can be assigned to the Streptococcus dysgalactiae subsp DYSGALACTIAE SUBSP. species Streptococcus dysgalactiae subspecies dysgalactiae DYSGALACTIAE dysgalactiae.

C86906 STREPTOCOCCUS STREPTOCOCC Any bacterial organism that can be assigned to the Streptococcus dysgalactiae subsp DYSGALACTIAE SUBSP. US species Streptococcus dysgalactiae subspecies equisimilis EQUISIMILIS EQUISIMILIS equisimilis.

C86789 STREPTOCOCCUS EQUI Any bacterial organism that can be assigned to the Streptococcus equi species Streptococcus equi.

C86790 STREPTOCOCCUS Any bacterial organism that can be assigned to the Streptococcus equinus EQUINUS species Streptococcus equinus.

C86791 STREPTOCOCCUS Any bacterial organism that can be assigned to the Streptococcus gallolyticus GALLOLYTICUS species Streptococcus gallolyticus.

C86408 STREPTOCOCCUS GAMMA-HEMO A bacteria that is assigned to the genus Streptococcus Gamma-Hemolytic Streptococcus GAMMA-HEMOLYTIC LYTIC that is unable to facilitate red blood cell lysis. STREPTOCOCC US

C86792 STREPTOCOCCUS Any bacterial organism that can be assigned to the Streptococcus gordonii GORDONII species Streptococcus gordonii.

C86793 STREPTOCOCCUS Any bacterial organism that can be assigned to the Streptococcus infantarius INFANTARIUS species Streptococcus infantarius.

C86794 STREPTOCOCCUS Any bacterial organism that can be assigned to the Streptococcus intermedius INTERMEDIUS species Streptococcus intermedius.

C86795 STREPTOCOCCUS MILLERI STREPTOCOCC Any bacterial organism that can be assigned to the Streptococcus milleri US MILLERI I species Streptococcus milleri.

C86796 STREPTOCOCCUS MILLERI A bacteria that belongs to the Milleri group of the Streptococcus milleri Group GROUP genus Streptococcus.

C86797 STREPTOCOCCUS MITIS A bacteria that belongs to the Mitis group of the genus Streptococcus mitis Group GROUP Streptococcus.

C86798 STREPTOCOCCUS MUTANS A bacteria that belongs to the Mutans group of the Streptococcus mutans Group GROUP genus Streptococcus.

C86799 STREPTOCOCCUS ORALIS Any bacterial organism that can be assigned to the Streptococcus oralis species Streptococcus oralis.

C86800 STREPTOCOCCUS STREPTOCOCC Any bacterial organism that can be assigned to the Streptococcus parasanguinis PARASANGUINIS US species Streptococcus parasanguinis. PARASANGUIS

C76384 STREPTOCOCCUS DIPLOCOCCUS Any bacterial organism that can be assigned to the Streptococcus pneumoniae PNEUMONIAE PNEUMONIAE species Streptococcus pneumoniae.

C86802 STREPTOCOCCUS Any bacterial organism that can be assigned to the Streptococcus porcinus PORCINUS species Streptococcus porcinus.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 248 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C85491 - MICROORG - Microorganism Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C86803 STREPTOCOCCUS GROUP A Any bacterial organism that can be assigned to the Streptococcus pyogenes PYOGENES BETA-HEMOLY species Streptococcus pyogenes. TIC STREPTOCOCC US PYOGENES

C86804 STREPTOCOCCUS Any bacterial organism that can be assigned to the Streptococcus salivarius SALIVARIUS species Streptococcus salivarius.

C86805 STREPTOCOCCUS A bacteria that belongs to the Salivarius group of the Streptococcus salivarius Group SALIVARIUS GROUP genus Streptococcus.

C86806 STREPTOCOCCUS STREPTOCOCC Any bacterial organism that can be assigned to the Streptococcus sanguinis SANGUINIS US SANGUIS species Streptococcus sanguinis.

C86807 STREPTOCOCCUS SUIS Any bacterial organism that can be assigned to the Streptococcus suis species Streptococcus suis.

C86808 STREPTOCOCCUS Any bacterial organism that can be assigned to the Streptococcus thermophilus THERMOPHILUS species Streptococcus thermophilus.

C86809 STREPTOCOCCUS UBERIS Any bacterial organism that can be assigned to the Streptococcus uberis species Streptococcus uberis.

C86810 STREPTOCOCCUS Any bacterial organism that can be assigned to the Streptococcus vestibularis VESTIBULARIS species Streptococcus vestibularis.

C86811 STREPTOCOCCUS STREPTOCOCC A non-taxonomic grouping of species within the Streptococcus viridans Group VIRIDANS GROUP US VIRIDANS; Streptococcus genus that are alpha-hemolytic and do VIRIDANS not express Lancefield antigens. STREPTOCOCC US

C14278 STREPTOMYCES Any bacteria that is not assigned to the species level Streptomyces but can be assigned to the Streptomyces genus level.

C86812 STREPTOMYCES ALBUS Any bacterial organism that can be assigned to the Streptomyces albus species Streptomyces albus.

C86813 STREPTOMYCES GRISEUS Any bacterial organism that can be assigned to the Streptomyces griseus species Streptomyces griseus.

C86814 STREPTOMYCES Any bacterial organism that can be assigned to the Streptomyces somaliensis SOMALIENSIS species Streptomyces somaliensis.

C86956 SUTTERELLA Any bacteria that is not assigned to the species level Sutterella but can be assigned to the Sutterella genus level.

C86815 SUTTONELLA Any bacteria that is not assigned to the species level Suttonella but can be assigned to the Suttonella genus level.

C86816 SUTTONELLA KINGELLA Any bacterial organism that can be assigned to the Suttonella indologenes INDOLOGENES INDOLOGENES species Suttonella indologenes.

C86817 TATLOCKIA MICDADEI LEGIONELLA Any bacterial organism that can be assigned to the Tatlockia micdadei MICDADEI species Legionella micdadei.

C86818 TATUMELLA Any bacteria that is not assigned to the species level Tatumella but can be assigned to the Tatumella genus level.

C86819 TATUMELLA PTYSEOS CDC GROUP Any bacterial organism that can be assigned to the Tatumella ptyseos EF-9 species Tatumella ptyseos.

C86820 TETRAGENOCOCCUS Any bacteria that is not assigned to the species level Tetragenococcus but can be assigned to the Tetragenococcus genus level.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 249 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C85491 - MICROORG - Microorganism Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C86821 TETRAGENOCOCCUS ENTEROCOCC Any bacterial organism that can be assigned to the Tetragenococcus solitarius SOLITARIUS US SOLITARIUS species Tetragenococcus solitarius.

C86907 TISSIERELLA Any bacteria that is not assigned to the species level Tissierella but can be assigned to the Tissierella genus level.

C86908 TISSIERELLA PRAEACUTA Any bacterial organism that can be assigned to the Tissierella praeacuta species Tissierella praeacuta.

C86822 TRABULSIELLA Any bacteria that is not assigned to the species level Trabulsiella but can be assigned to the Trabulsiella genus level.

C86823 TRABULSIELLA CDC ENTERIC Any bacterial organism that can be assigned to the Trabulsiella guamensis GUAMENSIS GROUP 90 species Trabulsiella guamensis.

C76385 TREPONEMA Any bacteria that is not assigned to the species level Treponema but can be assigned to the Treponema genus level.

C86825 TREPONEMA PALLIDUM Any bacterial organism that can be assigned to the Treponema pallidum species Treponema pallidum.

C91850 TREPONEMA PALLIDUM Any bacterial organism that can be assigned to the Treponema pallidum subsp SUBSP. ENDEMICUM species Treponema pallidum subspecies endemicum. endemicum

C91849 TREPONEMA PALLIDUM Any bacterial organism that can be assigned to the Treponema pallidum subsp pallidum SUBSP. PALLIDUM species Treponema pallidum subspecies pallidum.

C86909 TREPONEMA PALLIDUM TREPONEMA Any bacterial organism that can be assigned to the Treponema pallidum subsp pertenue SUBSP. PERTENUE PERTENUE species Treponema pallidum and subspecies pertenue.

C86826 TROPHERYMA Any bacteria that is not assigned to the species level Tropheryma but can be assigned to the Tropheryma genus level.

C86827 TROPHERYMA WHIPPLEI Any bacterial organism that can be assigned to the Tropheryma whipplei species Tropheryma whipplei.

C86828 TSUKAMURELLA Any bacteria that is not assigned to the species level Tsukamurella but can be assigned to the Tsukamurella genus level.

C86829 TSUKAMURELLA GORDONA Any bacterial organism that can be assigned to the Tsukamurella paurometabolum PAUROMETABOLUM AURANTIACA species Tsukamurella paurometabolum.

C86830 TURICELLA Any bacteria that is not assigned to the species level Turicella but can be assigned to the Turicella genus level.

C86831 TURICELLA OTITIDIS RHODOCOCCU Any bacterial organism that can be assigned to the Turicella otitidis S species Turicella otitidis. AURANTIAZUS

C86832 UREAPLASMA Any bacteria that is not assigned to the species level Ureaplasma but can be assigned to the Ureaplasma genus level.

C86833 UREAPLASMA T-MYCOPLASM Any bacterial organism that can be assigned to the Ureaplasma urealyticum UREALYTICUM A species Ureaplasma urealyticum.

C86834 VAGOCOCCUS Any bacteria that is not assigned to the species level Vagococcus but can be assigned to the Vagococcus genus level.

C86835 VARIBACULUM Any bacteria that is not assigned to the species level Varibaculum but can be assigned to the Varibaculum genus level.

C86836 VARIBACULUM Any bacterial organism that can be assigned to the Varibaculum cambriense CAMBRIENSE species Varibaculum cambriense.

C86837 VEILLONELLA Any bacteria that is not assigned to the species level Veillonella but can be assigned to the Veillonella genus level.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 250 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C85491 - MICROORG - Microorganism Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C86838 VEILLONELLA DISPAR Any bacterial organism that can be assigned to the Veillonella dispar species Veillonella dispar.

C86839 VEILLONELLA PARVULA Any bacterial organism that can be assigned to the Veillonella parvula species Veillonella parvula.

C76386 VIBRIO Any bacteria that is not assigned to the species level Vibrio but can be assigned to the Vibrio genus level.

C86840 VIBRIO ALGINOLYTICUS Any bacterial organism that can be assigned to the Vibrio alginolyticus species Vibrio alginolyticus.

C86841 VIBRIO CHOLERAE VIBRIO Any bacterial organism that can be assigned to the Vibrio cholerae COMMA species Vibrio cholerae.

C86842 VIBRIO FLUVIALIS CDC GROUP Any bacterial organism that can be assigned to the Vibrio fluvialis EF-6 species Vibrio fluvialis.

C86843 VIBRIO FURNISSII VIBRIO Any bacterial organism that can be assigned to the Vibrio furnissii FLUVIALIS species Vibrio furnissii. BIOGROUP 2

C86844 VIBRIO METSCHNIKOVII CDC ENTERIC Any bacterial organism that can be assigned to the Vibrio metschnikovii GROUP 16 species Vibrio metschnikovii.

C86845 VIBRIO MIMICUS SUCROSE Any bacterial organism that can be assigned to the Vibrio mimicus NEGATIVE species Vibrio mimicus. VIBRIO CHOLERAE

C86846 VIBRIO Any bacterial organism that can be assigned to the Vibrio parahaemolyticus PARAHAEMOLYTICUS species Vibrio parahaemolyticus.

C86847 VIBRIO VULNIFICUS BENECKEA Any bacterial organism that can be assigned to the Vibrio vulnificus VULNIFICA species Vibrio vulnificus.

C86848 WEEKSELLA Any bacteria that is not assigned to the species level Weeksella but can be assigned to the Weeksella genus level.

C86849 WEEKSELLA VIROSA CDC GROUP IIF Any bacterial organism that can be assigned to the Weeksella virosa species Weeksella virosa.

C86850 WOLINELLA Any bacteria that is not assigned to the species level Wolinella but can be assigned to the Wolinella genus level.

C86851 WOLINELLA Any bacterial organism that can be assigned to the Wolinella succinogenes SUCCINOGENES species Wolinella succinogenes.

C86852 YERSINIA Any bacteria that is not assigned to the species level Yersinia but can be assigned to the Yersinia genus level.

C86853 YERSINIA ALDOVAE Any bacterial organism that can be assigned to the Yersinia aldovae species Yersinia aldovae.

C86854 YERSINIA BERCOVIERI YERSINIA Any bacterial organism that can be assigned to the Yersinia bercovieri ENTEROLITICA species Yersinia bercovieri. BIOGROUP 3B

C86855 YERSINIA PASTEURELLA Any bacterial organism that can be assigned to the Yersinia enterocolitica ENTEROCOLITICA ENTEROCOLITI species Yersinia enterocolitica. CA

C86856 YERSINIA FREDERIKSENII Any bacterial organism that can be assigned to the Yersinia frederiksenii species Yersinia frederiksenii.

C86857 YERSINIA INTERMEDIA Any bacterial organism that can be assigned to the Yersinia intermedia species Yersinia intermedia.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 251 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C85491 - MICROORG - Microorganism Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C86858 YERSINIA KRISTENSENII Any bacterial organism that can be assigned to the Yersinia kristensenii species Yersinia kristensenii.

C86859 YERSINIA MOLLARETII YERSINIA Any bacterial organism that can be assigned to the Yersinia mollaretii ENTEROLITICA species Yersinia mollaretii. BIOGROUP 3A

C86860 YERSINIA PESTIS PASTEURELLA Any bacterial organism that can be assigned to the Yersinia pestis PESTIS species Yersinia pestis.

C86861 YERSINIA PASTEURELLA Any bacterial organism that can be assigned to the Yersinia pseudotuberculosis PSEUDOTUBERCULOSIS PSEUDOTUBER species Yersinia pseudotuberculosis. CULOSIS

C86862 YERSINIA ROHDEI Any bacterial organism that can be assigned to the Yersinia rohdei species Yersinia rohdei.

C86863 YERSINIA RUCKERI Any bacterial organism that can be assigned to the Yersinia ruckeri species Yersinia ruckeri.

C86864 YOKENELLA Any bacteria that is not assigned to the species level Yokenella but can be assigned to the Yokenella genus level.

C86865 YOKENELLA CDC ENTERIC Any bacterial organism that can be assigned to the Yokenella regensburgei REGENSBURGEI GROUP 45 species Yokenella regensburgei.

C86866 ZIMMERMANNELLA Any bacteria that is not assigned to the species level Zimmermannella but can be assigned to the Zimmermannella genus level.

C86867 ZIMMERMANNELLA ALBA Any bacterial organism that can be assigned to the Zimmermannella alba species Zimmermannella alba.

C86868 ZIMMERMANNELLA Any bacterial organism that can be assigned to the Zimmermannella bifida BIFIDA species Zimmermannella bifida.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 252 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C85495 - MSRESCAT - Microbiology Susceptibility Testing Result Category Codelist extensible: No

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C85560 INTERMEDIATE Intermediate The growth of microorganisms may be inhibited by Antimicrobial Intermediate antimicrobials that approach usually attainable blood Susceptibility Result and tissue concentrations. The response rates may be lower than for susceptible isolates. This category also includes a buffer zone, which should prevent small, uncontrolled, technical factors from causing major discrepancies in interpretations, especially for drugs with narrow pharmacotoxicity margins.

C85561 NONSUSCEPTIBLE Non Susceptible A category used for microorganisms that have only a Antimicrobial Nonsusceptibility susceptible interpretive criteria, but not an Result intermediate or resistant interpretive category (i.e., susceptible-only interpretive category). This category may be applied to new antimicrobial agents for which no resistant microorganisms have been encountered at the time the initial interpretive criteria are determined. Microorganisms that test with an MIC above or a zone measurement below the susceptible interpretive criteria are designated as nonsusceptible. A designation of nonsusceptible does not necessarily mean that a resistance mechanism(s) exists in the microorganism.

C48660 NOT APPLICABLE Not Applicable; Determination of a value is not relevant in the current Not Applicable NA context. (NCI)

C85562 RESISTANT Resistant The growth of microorganisms are not inhibited by the Antimicrobial Resistance Result usually achievable concentrations of the antimicrobial agent with normal dosages, and/or microorganisms demonstrate MICs or zone diameters that fall in the range where specific microbial resistance mechanisms (e.g. Beta-lactamases) are likely, and clinical efficacy of the agent against the microorganism has not been reliably shown in treatment studies.

C85563 SUSCEPTIBLE Susceptible The growth of microorganisms are inhibited by the Antimicrobial Susceptibility Result usually achievable concentrations of antimicrobial agent when the recommended dosage is used for the site of infection.

C85559 SUSCEPTIBLE-DOSE Susceptible-Dos The growth of microorganisms may be inhibited when Antimicrobial Dose Dependent DEPENDENT e Dependent higher than normal dosages of an antimicrobial agent Susceptibility Result are used and maximal possible blood concentration of the antimicrobial agent is achieved.

C17998 UNKNOWN U; Unknown Not known, not observed, not recorded, or refused. Unknown (NCI)

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 253 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C78738 - NCF - Never/Current/Former Classification Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C25471 CURRENT Occurring in or belonging to the present time. (NCI) Current

C25627 FORMER Previous Occurring prior to something else. (NCI) Previous

C70543 NEVER Not ever; at no time in the past. Never

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 254 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C66727 - NCOMPLT - Completion/Reason for Non-Completion Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C41331 ADVERSE EVENT Any untoward medical occurrence in a patient or Adverse Event clinical investigation subject administered a pharmaceutical product and which does not necessarily have a causal relationship with this treatment. An adverse event (AE) can therefore be any unintended sign (including an abnormal laboratory finding), symptom, or disease temporally associated with the use of a medicinal (investigational) product, whether or not related to the medicinal (investigational) product. NOTE: For further information, see the ICH Guideline for Clinical Safety Data Management: Definitions and Standards for Expedited Reporting. [Modified from ICH E2A] Synonyms: side effect, adverse experience. See also serious adverse event, serious adverse experience. (CDISC glossary)

C25250 COMPLETED To possess every necessary or normal part or Complete component or step; having come or been brought to a conclusion. (NCI)

C28554 DEATH The absence of life or state of being dead. (NCI) Death

C48226 LACK OF EFFICACY The lack of expected or desired effect related to a Lack of Efficacy therapy. (NCI)

C48227 LOST TO FOLLOW-UP The loss or lack of continuation of a subject to Lost To Follow-up follow-up.

C49631 NON-COMPLIANCE WITH An indication that a subject has not agreed with or Non-Compliance With Study Drug STUDY DRUG followed the instructions related to the study medication. (NCI)

C17649 OTHER Other Different than the one(s) previously specified or Other mentioned. (NCI)

C48250 PHYSICIAN DECISION A position, opinion or judgment reached after Physician Decision consideration by a physician with reference to subject. (NCI)

C25742 PREGNANCY Pregnancy is the state or condition of having a Pregnancy developing embryo or fetus in the body (uterus), after union of an ovum and spermatozoon, during the period from conception to birth. (NCI)

C35571 PROGRESSIVE DISEASE A disease process that is increasing in scope or Progressive Disease severity. (NCI)

C48251 PROTOCOL VIOLATION An event or decision that stands in contrast to the Protocol Violation guidelines set out by the protocol. (NCI)

C25746 RECOVERY A healing process and/or an outcome implying relative Recovery health. The term is typically used in the context of direct and indirect effects of sickness or injury. (NCI)

C49628 SCREEN FAILURE The potential subject who does not meet one or more Trial Screen Failure criteria required for participation in a trial.

C49632 STUDY TERMINATED BY An indication that a clinical study was stopped by its Study Terminated By Sponsor SPONSOR sponsor. (NCI)

C49633 TECHNICAL PROBLEMS A problem with some technical aspect of a clinical Technical Problem study, usually related to an instrument. (NCI)

C49634 WITHDRAWAL BY An indication that a study participant has removed Withdrawal by Subject SUBJECT itself from the study. (NCI)

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 255 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C66789 - ND - Not Done Codelist extensible: No

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C49484 NOT DONE Indicates a task, process or examination that has either Not Done not been initiated or completed. (NCI)

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 256 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C88025 - NEOPLASM - Neoplasm Type Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C7644 ADAMANTINOMA, ADAMANTINO A low-grade malignant neoplasm composed of Adamantinoma MALIGNANT MA epithelial cells and a spindle cell osteo-fibrous proliferation.

C4200 ADENOACANTHOMA, ADENOACANT A malignant neoplasm arising from glandular cells that Adenocarcinoma with Squamous MALIGNANT HOMA includes focal or extensive areas of squamous Metaplasia metaplasia.

C3766 ADENOCARCINOMA, CLEAR CELL A malignant neoplasm comprising glandular epithelial Clear Cell Adenocarcinoma CLEAR CELL, MALIGNANT CARCINOMA; clear cells. MESONEPHROI D CLEAR CELL ADENOCARCIN OMA; MESONEPHROI D CLEAR CELL CARCINOMA

C7359 ADENOCARCINOMA, ADENOCARCIN A malignant glandular neoplasm of the uterine lining. Endometrial Adenocarcinoma ENDOMETRIAL, OMA OF MALIGNANT ENDOMETRIU M; ADENOCARCIN OMA OF THE ENDOMETRIU M

C2852 ADENOCARCINOMA, A malignant neoplasm arising from glandular cells. Adenocarcinoma MALIGNANT

C26712 ADENOCARCINOMA, GELATINOUS An adenocarcinoma comprising neoplastic glandular Mucinous Adenocarcinoma MUCINOUS, MALIGNANT ADENOCARCIN cells containing intracytoplasmic mucin. OMA; MUCOID ADENOCARCIN OMA; MUCINOUS CARCINOMA; MUCOUS; ADENOCARCIN OMA; COLLOID ADENOCARCIN OMA; COLLOID CARCINOMA; MUCOID CARCINOMA; MUCOUS CARCINOMA; GELATINOUS CARCINOMA

C2853 ADENOCARCINOMA, An adenocarcinoma with papillary growth pattern. Papillary Adenocarcinoma PAPILLARY, MALIGNANT

C40310 ADENOCARCINOMA, CARCINOMA An adenocarcinoma with sebaceous differentiation. Sebaceous Carcinoma SEBACEOUS, MALIGNANT OF SEBACEOUS GLAND; CARCINOMA OF THE SEBACEOUS GLAND; SEBACEOUS GLAND CARCINOMA

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 257 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C88025 - NEOPLASM - Neoplasm Type Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C8984 ADENOFIBROMA, BENIGN BENIGN Benign mixed neoplasm comprised of Adenofibroma MIXED epithelial/glandular and mesenchymal structures. MUELLERIAN TUMOR

C4159 ADENOLIPOMA, BENIGN Benign mixed neoplasm comprised of Lipoadenoma epithelial/glandular and lipomatous structures.

C4196 ADENOMA, ACINAR CELL, ACINIC CELL A benign glandular epithelial neoplasm comprising Acinar Cell Adenoma BENIGN ADENOMA; secretory cells forming acinar patterns. ACINAR ADENOMA

C7580 ADENOMA, ADNEXAL, ADENOMA OF A benign glandular epithelial neoplasm comprising Skin Appendage Adenoma BENIGN ADNEXA; secretory cells forming acinar patterns. ADENOMA OF SKIN APPENDAGE; ADNEXAL ADENOMA

C9003 ADENOMA, CORTICAL A benign neoplasm arising from any of the adrenal Adrenal Cortex Adenoma ADRENOCORTICAL , CELL cortical layers. BENIGN ADENOMA; ADRENAL CORTICAL ADENOMA; ADRENOCORTI CAL ADENOMA; BENIGN ADRENAL ADENOMA; BENIGN ADENOMA OF THE ADRENAL GLAND; ADENOMA OF THE ADRENAL GLAND; ADRENAL ADENOMA; ADENOMA OF ADRENAL GLAND; ADENOMA OF THE ADRENAL CORTEX; BENIGN ADRENAL GLAND ADENOMA; BENIGN ADENOMA OF ADRENAL GLAND; ADENOMA OF ADRENAL CORTEX; ADRENAL GLAND ADENOMA

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 258 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C88025 - NEOPLASM - Neoplasm Type Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C3329 ADENOMA, ANTERIOR ADENOMA OF A benign neoplasm of the anterior lobe of the pituitary Pituitary Gland Adenoma LOBE PITUITARY GLAND, PITUITARY gland. BENIGN GLAND; ADENOMA OF PITUITARY; ADENOMA OF THE PITUITARY GLAND; ADENOMA OF THE PITUITARY; PITUITARY ADENOMA

C5950 ADENOMA, BASAL CELL, BASAL CELL A benign epithelial neoplasm characterized by the Salivary Gland Basal Cell Adenoma BENIGN ADENOMA OF presence of/arising from basal cells. SALIVARY GLAND; BASAL CELL ADENOMA OF THE SALIVARY GLAND; BASAL CELL ADENOMA; BENIGN BASAL CELL TUMOR

C2855 ADENOMA, BENIGN A benign neoplasm arising from epithelium. Adenoma

C3494 ADENOMA, BRONCHIAL, A benign neoplasia of the lung, arising from bronchial Lung Papillary Adenoma BENIGN epithelium.

C4140 ADENOMA, ADENOMA OF A benign lung neoplasm arising from the Alveolar Adenoma BRONCHIOLOALVEOLAR, THE ALVEOLI; alveolar/bronchiolar epithelium. BENIGN ADENOMA OF ALVEOLI

C46101 ADENOMA, C-CELL, PARAFOLLICU A benign neoplasm arising from C-cells of the thyroid Neoplastic C-Cell Hyperplasia BENIGN LAR CELL gland. ADENOMA

C6088 ADENOMA, CERUMINOUS CERUMINOUS A benign epithelial neoplasm derived from ceruminous External Auditory Canal Ceruminous GLAND, BENIGN ADENOMA; glands in the external auditory canal. Adenoma CERUMINOUS ADENOMA OF EXTERNAL AUDITORY CANAL; CERUMINOUS ADENOMA OF THE EXTERNAL AUDITORY CANAL; CERUMINOMA

C4151 ADENOMA, CLEAR CELL, A benign neoplasm comprising glands containing Clear Cell Adenoma BENIGN epithelial clear cells.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 259 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C88025 - NEOPLASM - Neoplasm Type Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C3502 ADENOMA, FOLLICULAR ADENOMA OF A benign neoplasm arising from follicular cells of the Thyroid Gland Follicular Adenoma CELL, BENIGN THE THYROID thyroid gland. GLAND; THYROID ADENOMA; FOLLICULAR ADENOMA OF THE THYROID; THYROID FOLLICULAR ADENOMA; ADENOMA OF THYROID; ADENOMA OF THYROID GLAND; FOLLICULAR ADENOMA OF THE THYROID GLAND; FOLLICULAR ADENOMA OF THYROID GLAND; ADENOMA OF THE THYROID; FOLLICULAR ADENOMA OF THYROID; THYROID GLAND ADENOMA; FOLLICULAR ADENOMA

C3758 ADENOMA, ADENOMA OF A benign epithelial neoplasm arising from hepatocytes. Hepatocellular Adenoma HEPATOCELLULAR, THE LIVER BENIGN CELLS; LIVER CELL ADENOMA; HCA; ADENOMA OF LIVER CELLS

C7126 ADENOMA, A benign neoplasm arising from the intrahepatic bile Intrahepatic Bile Duct Adenoma HEPATOCHOLANGIOCELL duct. ULAR, BENIGN

C65184 ADENOMA, ISLET CELL, ISLET CELL A benign neoplasm arising from the islet cells of the Islet Cell Adenoma BENIGN ADENOMA pancreas.

C46119 ADENOMA, LIGHT CELL, A benign epithelial neoplasm of the thyroid gland Thyroid Gland Clear Cell Follicular BENIGN comprising follicular cells with cytoplasmic clearing. Adenoma

C2973 ADENOMA, MUCINOUS, PSEUDOMUCI A benign, cystic epithelial neoplasm comprising cells Mucinous Cystadenoma BENIGN NOUS containing intracytoplasmic mucin. CYSTADENOM A; MUCINOUS CYSTOMA; MUCINOUS ADENOMA

C79951 ADENOMA, PAPILLARY, A benign epithelial neoplasm characterized by the Papillary Adenoma BENIGN presence of papillary epithelial patterns.

C60490 ADENOMA, PARS Rat Pars Distalis A benign epithelial neoplasm arising from the pars Rat Pars Distalis Adenoma DISTALIS, BENIGN Adenoma distalis of the anterior pituitary gland.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 260 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C88025 - NEOPLASM - Neoplasm Type Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C60493 ADENOMA, PARS Rat Pars A benign epithelial neoplasm arising from the pars Rat Pars Intermedia Adenoma INTERMEDIA, BENIGN Intermedia intermedia of the anterior pituitary gland. Adenoma

C98723 ADENOMA, PITUITARY A benign neoplasm of the pituitary gland. Experimental Organism Pituitary GLAND, BENIGN Gland Adenoma

C8383 ADENOMA, RENAL CELL, RENAL A benign neoplasm arising from the renal cortex. Renal Adenoma BENIGN TUBULE ADENOMA

C39956 ADENOMA, RETE TESTIS, A benign epithelial neoplasm arising from the rete Rete Testis Adenoma BENIGN testis.

C4174 ADENOMA, SEBACEOUS, SEBACEOUS A benign neoplasm arising from sebaceous glands. Sebaceous Adenoma BENIGN GLAND ADENOMA; ADENOMA OF THE SEBACEOUS GLAND; ADENOMA OF SEBACEOUS GLAND; SKIN APPENDAGE SEBACEOUS ADENOMA

C92180 ADENOMA, SERTOLIFORM Rat Sertoliform A benign tubular adenoma with Sertoli cell Rat Sertoliform Tubular Adenoma TUBULAR, BENIGN Tubular Adenoma differentiation.

C7560 ADENOMA, SWEAT ADENOMA OF A benign epithelias neoplasm arising from sweat Sweat Gland Adenoma GLAND, BENIGN THE SWEAT glands. GLAND; ADENOMA OF SWEAT GLAND

C4133 ADENOMA, TUBULAR A benign neoplasm arising from glandular epithelium, Tubular Adenoma CELL, BENIGN characterized by a tubular architectural pattern.

C79953 ADENOMA, A benign ovarian epithelial neoplasm characterized by Tubulostromal Adenoma TUBULOSTROMAL, the presence of tubular structures and interstitial BENIGN stroma.

C84357 ADENOMA, YOLK SAC, A benign epithelial neoplasm arising from the yolk sac. Yolk Sac Adenoma BENIGN

C98800 ADENOMA, ZYMBAL'S A benign neoplasm of the rodent Zymbal's gland with Zymbal's Gland Adenoma GLAND sebaceous and/or squamous differentiation.

C3726 ADENOMYOMA, BENIGN A benign neoplasm characterized by the presence of a Adenomyoma glandular and a mesenchymal component.

C83488 ADRENAL TUMOR, SUBCAPSULAR A benign neoplasm located beneath the adrenal Benign Subcapsular Adrenal Tumor SUBCAPSULAR, BENIGN SINGLE CELL capsule. ADENOMA, ADRENAL

C83489 ADRENAL TUMOR, SUBCAPSULAR A malignant neoplasm located beneath the adrenal Malignant Subcapsular Adrenal SUBCAPSULAR, SINGLE CELL capsule. Tumor MALIGNANT CARCINOMA, ADRENAL

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 261 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C88025 - NEOPLASM - Neoplasm Type Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C82973 ADRENAL TUMOR, SUBCAPSULAR A neoplasm located beneath the adrenal capsule in Subcapsular Adrenal Tumor SUBCAPSULAR, CELL TUMOR, which the malignancy status has not been established. UNDETERMINED ADRENAL; SUBCAPSULAR CELL TUMOR, ADRENAL

C2858 ADRENOCORTICAL ADRENAL A neoplasm of the adrenal cortex in which the Adrenal Cortex Neoplasm NEOPLASM, CORTEX malignancy status has not been established. UNDETERMINED TUMOR; ADRENOCORTI CAL NEOPLASM; ADRENOCORTI CAL TUMOR

C7111 AMELOBLASTOMA, A benign odontogenic neoplasm arising from the Benign Ameloblastoma BENIGN epithelial component of the embryonic tooth.

C54297 AMELOBLASTOMA, MALIGNANT A malignant odontogenic neoplasm arising from the Metastasizing Ameloblastoma MALIGNANT AMELOBLAST epithelial component of the embryonic tooth. OMA

C4313 AMELOBLASTOMA, A odontogenic neoplasm arising from the epithelial Ameloblastoma UNDETERMINED component of the embryonic tooth of undetermined malignancy status.

C3799 ANGIOFIBROMA, BENIGN FIBROANGIOM A benign, morphologic variant of fibroma Angiofibroma A, BENIGN; characterized by the presence of numerous dilated FIBROUS vascular channels. PAPULE; TELANGIECTAT IC FIBROMA; ANGIOFIBROM ATOUS HYPERPLASIA

C3733 ANGIOLIPOMA, BENIGN ANGIOLIPOMA A lipoma characterized by prominent vascularization. Angiolipoma

C9477 ASTROCYTOMA, GRADE III A malignant neoplasm of the brain or spinal cord Anaplastic Astrocytoma ANAPLASTIC , MALIGNANT ASTROCYTIC originating from astrocytes, exhibiting poor TUMOR; differentiation (anaplasia). GRADE III ASTROCYTOM A; GRADE III ASTROCYTIC NEOPLASM; MALIGNANT ASTROCYTOM A

C4047 ASTROCYTOMA, GRADE I A benign neoplasm of the brain or spinal cord arising Pilocytic Astrocytoma PILOCYTIC, BENIGN ASTROCYTIC from astrocytes associated with single or multiple NEOPLASM; cysts. GRADE I ASTROCYTOM A; GRADE I ASTROCYTIC TUMOR

C60781 ASTROCYTOMA, ASTROCYTOM A neoplasm of the brain or spinal cord exhibiting Astrocytoma UNDETERMINED A, DIFFUSE astrocytic differentiation, but in which the malignancy status has not been established.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 262 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C88025 - NEOPLASM - Neoplasm Type Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C4614 BASOSQUAMOUS TUMOR, CUTANEOUS A benign papillary neoplasm of the skin. Skin Papilloma BENIGN PAPILLOMA; PAPILLOMA OF SKIN; PAPILLOMA OF THE SKIN

C2922 BASOSQUAMOUS TUMOR, BASOSQUAMO A basal cell carcinoma (skin neoplasm) which displays Skin Basosquamous Cell Carcinoma MALIGNANT US squamous differentiation. CARCINOMA; SKIN MIXED BASAL AND SQUAMOUS CELL CARCINOMA; BASOSQUAMO US CELL CARCINOMA

C72074 CARCINOID TUMOR, MALIGNANT A malignant neuroendocrine neoplasm arising from Atypical Carcinoid Tumor ATYPICAL, MALIGNANT CARCINOID enterochromaffin cells in the gastrointestinal tract and TUMOR (less common) in the bronchi exhibiting atypia.

C2915 CARCINOID TUMOR, CARCINOID; A neuroendocrine neoplasm arising from Carcinoid Tumor UNDETERMINED WELL-DIFFERE enterochromaffin cells in the gastrointestinal tract and NTIATED (less common) the bronchi with undetermined ENDOCRINE malignancy status. NEOPLASM; CARCINOID NEOPLASM

C4147 CARCINOMA, ACIDOPHIL, EOSINOPHIL A malignant epithelial neoplasm of the anterior Pituitary Gland Acidophil Carcinoma MALIGNANT CARCINOMA; pituitary gland in which the neoplastic cells stain ACIDOPHIL positive with acidic dyes. ADENOCARCIN OMA; ACIDOPHIL CARCINOMA; EOSINOPHIL ADENOMCARC INOMA

C3768 CARCINOMA, ACINAR ACINAR A malignant glandular epithelial neoplasm comprising Acinar Cell Carcinoma CELL, MALIGNANT ADENOCARCIN secretory cells forming acinar patterns. OMA; ACINIC CELL ADENOCARCIN OMA; ACINAR CARCINOMA; ACINAR CELL ADENOCARCIN OMA; ACINIC CELL CARCINOMA

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 263 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C88025 - NEOPLASM - Neoplasm Type Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C3727 CARCINOMA, MIXED An epithelial neoplasm composed of malignant Adenosquamous Carcinoma ADENOSQUAMOUS, ADENOCARCIN glandular and malignant squamous cells. MALIGNANT OMA AND SQUAMOUS CARCINOMA; MIXED ADENOCARCIN OMA AND EPIDERMOID CELL CARCINOMA; MIXED ADENOCARCIN OMA AND SQUAMOUS CELL CARCINOMA; MIXED ADENOCARCIN OMA AND EPIDERMOID CARCINOMA

C3775 CARCINOMA, ADNEXAL, SKIN A malignant epithelial neoplasm arising from Adnexal Carcinoma MALIGNANT APPENDAGE sebaceous or sweat glands or from hair follicles. CARCINOMA; CARCINOMA OF ADNEXA; CARCINOMA OF SKIN APPENDAGE

C9325 CARCINOMA, CORTICAL A malignant epithelial neoplasm arising from adrenal Adrenal Cortex Carcinoma ADRENOCORTICAL, CELL cortical cells. MALIGNANT CARCINOMA; ADENOCARCIN OMA, ADRENOCORTI CAL, MALIGNANT; ADRENAL CORTEX ADENOCARCIN OMA; ADRENAL CORTEX CANCER; ADRENAL CORTICAL ADENOCARCIN OMA; ADRENAL CORTICAL CARCINOMA; ADRENOCORTI CAL CARCINOMA

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 264 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C88025 - NEOPLASM - Neoplasm Type Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C2921 CARCINOMA, BASAL CELL, BASAL CELL A malignant epithelial neoplasm arising from basal Skin Basal Cell Carcinoma MALIGNANT EPITHELIOMA; cells of the epidermis and pilosebaceous unit of skin BASAL CELL [the dermis]. CANCER; BASAL CELL CARCINOMA OF SKIN; BASAL CELL CARCINOMA OF THE SKIN; BASAL CELL CARCINOMA; BASAL CELL EPITHELIOMA; BASAL CELL SKIN CARCINOMA; BASILOMA; BCC; RODENT ULCER

C35875 CARCINOMA, BRONCHIAL, A malignant neoplasia of the lung, arising from Bronchogenic Carcinoma MALIGNANT bronchial epithelium.

C2923 CARCINOMA, BRONCHIOALV A malignant lung neoplasm originating from the Bronchioloalveolar Carcinoma BRONCHIOLOALVEOLAR, EOLAR alveolar/bronchiolar epithelium. MALIGNANT ADENOCARCIN OMA OF LUNG; BRONCHIOLO- ALVEOLAR LUNG CARCINOMA; BRONCHIOLOA LVEOLAR ADENOCARCIN OMA OF LUNG; BRONCHIOLOA LVEOLAR LUNG ADENOCARCIN OMA; BAC; BRONCHIOLO- ALVEOLAR CARCINOMA OF LUNG; BRONCHIOLO- ALVEOLAR CARCINOMA OF THE LUNG; BRONCHIOALV EOLAR LUNG CARCINOMA; BRONCHIOLOA LVEOLAR ADENOCARCIN OMA OF THE LUNG; BRONCHIOALV EOLAR ADENOCARCIN OMA OF THE LUNG

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 265 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C88025 - NEOPLASM - Neoplasm Type Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C3879 CARCINOMA, C-CELL, PARAFOLLICU A neuroendocrine malignant epithelial neoplasm Thyroid Gland Medullary Carcinoma MALIGNANT LAR CELL arising from C-cells of the thyroid gland. CARCINOMA; C CELL CARCINOMA; MEDULLARY CARCINOMA OF THYROID GLAND; THYROID GLAND NEUROENDOC RINE CARCINOMA; MEDULLARY CARCINOMA OF THE THYROID GLAND; MEDULLARY THYROID CANCER; PARAFOLLICU LAR CELL CARCINOMA; MEDULLARY THYROID CARCINOMA; MEDULLARY CARCINOMA OF THYROID; MEDULLARY CARCINOMA; MTC; MEDULLARY CARCINOMA OF THE THYROID; MEDULLARY THYROID GLAND CARCINOMA; THYROID MEDULLARY CARCINOMA

C4176 CARCINOMA, A malignant neoplasm derived from ceruminous glands Ceruminous Adenocarcinoma CERUMINOUS GLAND, in the external auditory canal. MALIGNANT

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 266 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C88025 - NEOPLASM - Neoplasm Type Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C4715 CARCINOMA, CHOROID CHOROID A malignant neoplasm arising from the choroid plexus Choroid Plexus Carcinoma PLEXUS, MALIGNANT PLEXUS of the brain. CANCER; CARCINOMA OF THE CHOROID PLEXUS; CARCINOMA OF CHOROID PLEXUS; CANCER OF THE CHOROID PLEXUS; CANCER OF CHOROID PLEXUS; ANAPLASTIC CHOROID PLEXUS PAPILLOMA

C3752 CARCINOMA, CARCINOMA, A non-seminomatous malignant germ cell neoplasm of Embryonal Carcinoma EMBRYONAL, MALIGNANT EMBRYONAL, the testis or ovary. MALIGNANT

C7558 CARCINOMA, CARCINOMA A malignant epithelial neoplasm arising from the lining Endometrial Carcinoma ENDOMETRIAL, OF of the uterine body cavity. MALIGNANT ENDOMETRIU M; CARCINOMA OF THE ENDOMETRIU M

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 267 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C88025 - NEOPLASM - Neoplasm Type Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C8054 CARCINOMA, FOLLICULAR FOLLICULAR A malignant neoplasia arising from follicular cells of Thyroid Gland Follicular Carcinoma CELL, MALIGNANT THYROID the thyroid gland. CANCER; WELL-DIFFERE NTIATED FOLLICULAR CARCINOMA; FOLLICULAR ADENOCARCIN OMA; FOLLICULAR CANCER OF THE THYROID; FOLLICULAR CARCINOMA OF THE THYROID GLAND; WELL-DIFFERE NTIATED FOLLICULAR ADENOCARCIN OMA; FOLLICULAR CARCINOMA; FOLLICULAR CARCINOMA OF THYROID GLAND; FOLLICULAR CANCER OF THYROID; FOLLICULAR THYROID CARCINOMA; THYROID FOLLICULAR CARCINOMA; FOLLICULAR CARCINOMA OF THE THYROID; FOLLICULAR CANCER OF THYROID GLAND; FOLLICULAR CANCER OF THE THYROID GLAND; FOLLICULAR CARCINOMA OF THYROID; FOLLICULAR THYROID GLAND CARCINOMA

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 268 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C88025 - NEOPLASM - Neoplasm Type Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C3099 CARCINOMA, CARCINOMA A malignant neoplasm arising from hepatocytes. Hepatocellular Carcinoma HEPATOCELLULAR, OF LIVER MALIGNANT CELLS; PRIMARY CARCINOMA OF THE LIVER CELLS; LIVER CELL CARCINOMA; HEPATOMA; CARCINOMA OF THE LIVER CELLS; PRIMARY CARCINOMA OF LIVER CELLS; HCC

C3828 CARCINOMA, A malignant neoplasm of the liver containing Combined Hepatocellular Carcinoma HEPATOCHOLANGIOCELL unequivocal elements of both hepatocellular and and Cholangiocarcinoma ULAR, MALIGNANT cholangiocarcinoma intimately admixed.

C2917 CARCINOMA, IN SITU, EPITHELIAL A malignant epithelial neoplasm confined to the Carcinoma In Situ MALIGNANT TUMOR, IN epithelial layer and without evidence of further tissue SITU, invasion. MALIGNANT; INTRAEPITHELI AL CARCINOMA; NON-INVASIVE CARCINOMA; CIS

C3770 CARCINOMA, ISLET CELL, PANCREATIC A malignant endocrine neoplasm arising from islets of Pancreatic Neuroendocrine MALIGNANT NEUROENDOC Langerhans of the pancreas. Carcinoma RINE CARCINOMA; MALIGNANT PANCREATIC ENDOCRINE TUMOR; MALIGNANT ISLET CELL TUMOR; ISLET CELL CANCER; ISLET CELL CARCINOMA

C2916 CARCINOMA, MALIGNANT EPITHELIOMA A malignant epithelial neoplasm. Carcinoma MALIGNANT; EPITHELIAL CARCINOMA; MALIGNANT EPITHELIAL NEOPLASM; MALIGNANT EPITHELIAL TUMOR; MALIGNANT EPITHELIOMA

C6878 CARCINOMA, MIXED, A malignant pancreatic neoplasm characterized by the Mixed Acinar-Neuroendocrine ACINAR-ISLET CELL, presence of a mixture of acinar and islet cell elements. Carcinoma of the Pancreas MALIGNANT

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 269 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C88025 - NEOPLASM - Neoplasm Type Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C3773 CARCINOMA, NEURAL A malignant neuroendocrine neoplasm comprising Neuroendocrine Carcinoma NEUROENDOCRINE CELL, CREST TUMOR, cells containing secretory granules. MALIGNANT MALIGNANT; NEUROENDOC RINE TUMOR, MALIGNANT; NEUROENDOC RINE CELL CARCINOMA; NEUROENDOC RINE CARCINOMA

C60491 CARCINOMA, PARS Rat Pars Distalis A malignant epithelial neoplasm arising from the pars Rat Pars Distalis Carcinoma DISTALIS, MALIGNANT Carcinoma distalis of the pituitary gland.

C92183 CARCINOMA, PARS Rat Pars A malignant epithelial neoplasm arising from the pars Rat Pars Intermedia Carcinoma INTERMEDIA, MALIGNANT Intermedia intermedia of the pituitary gland. Carcinoma

C9385 CARCINOMA, RENAL ADENOCARCIN A malignant neoplasm arising from renal parenchyma. Renal Cell Carcinoma CELL, MALIGNANT OMA OF THE KIDNEY; RENAL CELL CANCER; KIDNEY ADENOCARCIN OMA; RCC; RENAL CELL CARCINOMA, STAGE UNSPECIFIED; RENAL CELL ADENOCARCIN OMA; ADENOCARCIN OMA OF KIDNEY

C39807 CARCINOMA, RENAL, RENAL A malignant neoplasm of the kidney, characterized by Mucinous Tubular and Spindle Cell TUBULAR, MALIGNANT TUBULE the presence of tubules. Carcinoma of the Kidney CARCINOMA; MUCINOUS TUBULAR AND SPINDLE CELL CARCINOMA OF THE KIDNEY

C27004 CARCINOMA, SPINDLE PSEUDOSARCO A malignant epithelial neoplasm characterized by the Sarcomatoid Carcinoma CELL, MALIGNANT MATOUS presence of spindle cells. CARCINOMA; SPINDLE CELL CARCINOMA

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 270 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C88025 - NEOPLASM - Neoplasm Type Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C27093 CARCINOMA, SQUAMOUS EPIDERMOID A malignant epithelial neoplasm confined to the Stage 0 Squamous Cell Carcinoma CELL, IN SITU, CELL squamous epithelium, without invasion of underlying MALIGNANT CARCINOMA tissues. IN SITU; EPIDERMOID CARCINOMA IN SITU; GRADE III SQUAMOUS INTRAEPITHELI AL NEOPLASIA; INTRAEPITHELI AL SQUAMOUS CELL CARCINOMA; SQUAMOUS CELL CARCINOMA IN SITU; GRADE 3 SQUAMOUS INTRAEPITHELI AL NEOPLASIA; SQUAMOUS CARCINOMA IN SITU

C2929 CARCINOMA, SQUAMOUS MALIGNANT A malignant neoplasm arising from squamous Squamous Cell Carcinoma CELL, MALIGNANT EPIDERMOID epithelial cells. CELL NEOPLASM; SQUAMOUS CARCINOMA; EPIDERMOID CARCINOMA; MALIGNANT SQUAMOUS CELL TUMOR; SQUAMOUS CELL EPITHELIOMA; EPIDERMOID CELL CANCER; MALIGNANT SQUAMOUS CELL NEOPLASM; MALIGNANT EPIDERMOID CELL TUMOR; SQUAMOUS CELL CANCER

C6938 CARCINOMA, SWEAT CARCINOMA A malignant neoplasm arising from sweat glands. Sweat Gland Carcinoma GLAND, MALIGNANT OF SWEAT GLAND; CARCINOMA OF THE SWEAT GLAND

C2930 CARCINOMA, TRANSITIONAL A malignant neoplasm arising from transitional Transitional Cell Carcinoma TRANSITIONAL CELL, CARCINOMA epithelium, usually affecting the urinary bladder, MALIGNANT ureter, or renal pelvis.

C65192 CARCINOMA, TUBULAR A malignant glandular neoplasm exhibiting tubular Tubular Adenocarcinoma CELL, MALIGNANT structures.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 271 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C88025 - NEOPLASM - Neoplasm Type Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C80356 CARCINOMA, A malignant epithelial neoplasm of the ovary with Tubulostromal Adenocarcinoma TUBULOSTROMAL, tubular and stromal neoplastic components. MALIGNANT

C3692 CARCINOMA, ANAPLASTIC A malignant epithelial neoplasm exhibiting poor Undifferentiated Carcinoma UNDIFFERENTIATED, CARCINOMA; differentiation (anaplasia). MALIGNANT CARCINOMA, UNDIFFERENTI ATED

C98801 CARCINOMA, ZYMBAL'S A malignant neoplasm of the rodent Zymbal's gland Zymbal's Gland Carcinoma GLAND with sebaceous and/or squamous differentiation.

C34448 CARCINOSARCOMA, A malignant neoplasm comprising a mixture of Carcinosarcoma MALIGNANT carcinomatous and sarcomatous elements.

C79950 CHEMODECTOMA, BENIGN A benign neoplasm of the chemoreceptor system (e.g. Benign Carotid Body Paraganglioma BENIGN CHEMODECTO carotid body, glomus jugulare, glomus vagale). MA

C3574 CHEMODECTOMA, MALIGNANT A malignant neoplasm of the chemoreceptor system Malignant Carotid Body MALIGNANT TUMOR OF THE (e.g. carotid body, glomus jugulare, glomus vagale). Paraganglioma CAROTID BODY; MALIGNANT CAROTID BODY TUMOR; MALIGNANT NEOPLASM OF THE CAROTID BODY; MALIGNANT NEOPLASM OF CAROTID BODY; MALIGNANT CAROTID BODY NEOPLASM; MALIGNANT TUMOR OF CAROTID BODY

C2932 CHEMODECTOMA, PARAGANGLIO A neoplasm of the chemoreceptor system (e.g. carotid Carotid Body Paraganglioma UNDETERMINED MA OF body, glomus jugulare, glomus vagale) for which the CAROTID malignancy status has not be established. BODY; CHEMODECTO MA; PARAGANGLIO MA OF THE CAROTID BODY; TUMOR OF THE CAROTID BODY; CAROTID BODY TUMOR; CAROTID BODY CHEMODECTO MA; TUMOR OF CAROTID BODY

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 272 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C88025 - NEOPLASM - Neoplasm Type Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C35417 CHOLANGIOCARCINOMA, PERIPHERAL A malignant neoplasm of the liver arising Intrahepatic Cholangiocarcinoma INTRAHEPATIC, CHOLANGIOCA from/comprising cells resembling those of bile ducts. MALIGNANT RCINOMA; INTRAHEPATIC CARCINOMA OF BILE DUCT; INTRAHEPATIC CARCINOMA OF THE BILE DUCT; INTRAHEPATIC BILE DUCT CARCINOMA; HEPATOCHOL ANGIOCELLUL AR CARCINOMA

C4436 CHOLANGIOCARCINOMA, CHOLANGIOCE A malignant neoplasm arising from/comprising cells Cholangiocarcinoma MALIGNANT LLULAR resembling those of bile ducts. CARCINOMA

C2942 CHOLANGIOMA, BENIGN HEPATOCHOL A benign neoplasm arising from/comprising cells Bile Duct Adenoma ANGIOMA; resembling those of bile ducts. CHOLANGIOM A; ADENOMA OF BILE DUCT; ADENOMA OF THE BILE DUCT; CHOLANGIOA DENOMA; CHOLANGIOFI BROMA; HEPATOCHOL ANGIOCELLUL AR ADENOMA

C53459 CHONDROMA, BENIGN A benign, well circumscribed neoplasm arising from Chondroma the hyaline cartilage in soft tissue or bone. It is characterized by the presence of chondrocytes.

C2946 CHONDROSARCOMA, A malignant mesenchymal neoplasm arising from Chondrosarcoma MALIGNANT cartilage-forming tissues.

C2947 CHORDOMA, MALIGNANT A malignant bone neoplasm arising from the remnants Chordoma of the fetal notochord.

C2948 CHORIOCARCINOMA, CHORIOEPITHE A malignant neoplasm arising from placental Choriocarcinoma MALIGNANT LIOMA; trophoblast cells. They generally arise in the uterus. CHORIOEPITHE LIOMA

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 273 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C88025 - NEOPLASM - Neoplasm Type Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C2964 CRANIOPHARYNGIOMA, NEOPLASM OF A benign epithelial neoplasm of the sellar region, Craniopharyngioma BENIGN RATHKE'S presumably derived from Rathke pouch epithelium. POUCH; TUMOR OF RATHKE'S POUCH; RATHKE POUCH TUMOR; RATHKE POUCH NEOPLASM; RATHKE'S POUCH TUMOR; RATHKE'S POUCH NEOPLASM; CYSTOMA

C79949 CRANIOPHARYNGIOMA, CARCINOMA A malignant epithelial neoplasm of the sellar region, Carcinoma Arising from MALIGNANT ARISING FROM presumably derived from Rathke pouch epithelium. Craniopharyngioma CRANIOPHARY NGIOMA

C2971 CYSTADENOCARCINOMA, A malignant cystic epithelial neoplasm arising from Cystadenocarcinoma MALIGNANT glandular epithelium.

C3777 CYSTADENOCARCINOMA, A malignant cystic epithelial neoplasm arising from Papillary Cystadenocarcinoma PAPILLARY, MALIGNANT glandular epithelium exhibiting papillary structures.

C2972 CYSTADENOMA, BENIGN CYSTOMA A benign cystic epithelial neoplasm arising from Cystadenoma glandular epithelium.

C2974 CYSTADENOMA, A benign cystic epithelial neoplasm arising from Papillary Cystadenoma PAPILLARY, BENIGN glandular epithelium exhibiting papillary structures.

C3555 DECIDUOMA, MALIGNANT MALIGNANT A malignant neoplasm arising from decidua (placental) Malignant Placental Neoplasm PLACENTAL cells. TUMOR; MALIGNANT PLACENTAL NEOPLASM; MALIGNANT NEOPLASM OF PLACENTA; MALIGNANT TUMOR OF THE PLACENTA; MALIGNANT NEOPLASM OF THE PLACENTA; MALIGNANT TUMOR OF PLACENTA; MALIGNANT PLACENTAL TUMOR

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 274 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C88025 - NEOPLASM - Neoplasm Type Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C4858 DECIDUOMA, DECIDUOMA A neoplasm arising from decidua (placental) cells in Placental Neoplasm UNDETERMINED NOS; which the malignancy status has not been established. PLACENTA NEOPLASMS; PLACENTA TUMORS; PLACENTA TUMOR; TUMOR OF PLACENTA; TUMOR OF THE PLACENTA; PLACENTAL TUMORS; PLACENTAL TUMOR; NEOPLASM OF THE PLACENTA; PLACENTA NEOPLASM; NEOPLASM OF PLACENTA

C9011 DERMOID CYST, BENIGN BENIGN A benign neoplasm comprised of a cyst, lined by Dermoid Cyst CYSTIC mature epidermis-like tissue with dermal appendages. TERATOMA; DERMOID; MATURE CYSTIC TERATOMA

C2996 DYSGERMINOMA, A malignant germ cell neoplasm characterized by the Dysgerminoma MALIGNANT presence of a monotonous primitive germ cell population, primarily in the ovary.

C4049 EPENDYMOMA, WHO GRADE III A malignant neoplasm of ependymal origin with Anaplastic Ependymoma ANAPLASTIC , MALIGNANT EPENDYMAL anaplastic cellular morphology. TUMOR; UNDIFFERENTI ATED EPENDYMAL NEOPLASM; MALIGNANT EPENDYMOMA ; UNDIFFERENTI ATED EPENDYMAL TUMOR; UNDIFFERENTI ATED EPENDYMOMA ; ANAPLASTIC EPENDYMAL NEOPLASM; ANAPLASTIC EPENDYMAL TUMOR; WHO GRADE III EPENDYMAL NEOPLASM

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 275 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C88025 - NEOPLASM - Neoplasm Type Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C3017 EPENDYMOMA, WHO GRADE II A neoplasm of ependymal origin, for which the Ependymoma UNDETERMINED EPENDYMAL malignancy status has not been established. TUMOR; WHO GRADE II EPENDYMAL NEOPLASM

C4092 EPITHELIOMA, BENIGN BENIGN A benign neoplasm arising from epithelial cells of the Benign Epithelial Neoplasm EPITHELIAL skin. TUMOR; BENIGN EPITHELIOMA; BENIGN NEOPLASM OF EPITHELIUM; BENIGN TUMOR OF THE EPITHELIUM; BENIGN NEOPLASM OF THE EPITHELIUM; BENIGN TUMOR OF EPITHELIUM

C80349 EPITHELIOMA, CYSTIC A benign cystic epithelial neoplasm featuring a central Cystic Keratinizing Epithelioma KERATINIZING, BENIGN keratin mass surrounded by squamous epithelium.

C84356 EPITHELIOMA, A benign cystic epithelial neoplasm characterized by Non-Keratinizing Epithelioma NON-KERATINIZING, the absence of keratin production. BENIGN

C2928 FIBROADENOCARCINOMA, ADENOCARCIN A malignant neoplasm originating from glandular cells Scirrhous Adenocarcinoma MALIGNANT OMA WITH with a fibrous or fibroblastic component. PRODUCTIVE FIBROSIS; FIBROCARCIN OMA; SCIRRHOUS CARCINOMA

C3744 FIBROADENOMA, BENIGN FIBROADENO A benign neoplasm originating from glandular cells Fibroadenoma MA OF with a fibrous or fibroblastic component. BREAST; BREAST FIBROADENO MA; FIBROADENO MA OF THE BREAST

C4249 FIBROLIPOMA, BENIGN A benign neoplasm comprising mature adipocytes, Fibrolipoma characterized by areas of abundant fibrous tissue.

C3041 FIBROMA, BENIGN A benign neoplasm arising from fibrous tissue. Fibroma

C4314 FIBROMA, ODONTOGENIC, CENTRAL A benign intraosseous neoplasm arising from Odontogenic Fibroma BENIGN ODONTOGENIC tooth-forming tissues in the mandible and maxilla, FIBROMA characterized by the presence of islands of odontogenic epithelium.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 276 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C88025 - NEOPLASM - Neoplasm Type Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C8422 FIBROMA, OSSIFYING, OSSIFYING A benign fibrous neoplasm characterized by a Ossifying Fibroma BENIGN FIBROMA; mineralized component (woven bone, lamellar bone, or CEMENTIFYIN cementum-like material). G FIBROMA; CEMENTO-OSS IFYING FIBROMA

C66760 FIBROMYXOMA, BENIGN FIBROMYXOM A benign soft-tissue neoplasm of uncertain lineage, Fibromyxoid Neoplasm A characterized by the presence of neoplastic spindle-shaped to round cells and a fibromyxoid stroma.

C3337 FIBROPAPILLOMA, A benign polypoid tumor comprising fibrous tissue and Fibroepithelial Polyp BENIGN epithelium.

C3043 FIBROSARCOMA, A malignant mesenchymal neoplasm of the soft tissue Fibrosarcoma MALIGNANT and bone.

C3788 GANGLIOGLIOMA, A neuroepithelial neoplasm comprised of neoplastic Ganglioglioma UNDETERMINED ganglion cells and neoplastic glial cells, in which the malignancy status has not been established.

C3790 GANGLIONEUROBLASTOM A malignant neoplasm characterized by the presence of Ganglioneuroblastoma A, MALIGNANT neuroblastic and ganglion cells and a stroma with Schwannian differentiation.

C3049 GANGLIONEUROMA, A benign neoplasm characterized by the presence of Ganglioneuroma BENIGN ganglion cells and spindle cell proliferation, located primarily in the brain, ganglia, or adrenal medulla.

C27477 GIANT CELL TUMOR, OSTEOCLASTO A benign neoplasm of bone comprised of giant cells Benign Giant Cell Tumor of Bone BENIGN MA, BENIGN; (osteoclast-like) and mononuclear cells. BENIGN BONE GIANT CELL TUMOR

C4090 GIANT CELL TUMOR, MALIGNANT A malignant neoplasm of bone comprised of giant Malignant Giant Cell Neoplasm MALIGNANT GIANT CELL cells (osteoclast-like) and mononuclear cells. TUMOR

C3055 GIANT CELL TUMOR, TUMOR OF A neoplasm of bone comprised of giant cells Giant Cell Tumor UNDETERMINED GIANT CELL; (osteoclast-like) and mononuclear cells, for which the TUMOR OF THE malignancy status has not been established. GIANT CELL

C4822 GLIOMA, MALIGNANT MALIGNANT A malignant neuroglial neoplasm. The term can apply Malignant Glioma NEUROGLIAL to several primary neoplasm of the brain and spinal NEOPLASM; cord, including astrocytoma and oligodendroglioma in MALIGNANT addition to others. GLIAL NEOPLASM; MALIGNANT NEUROGLIAL TUMOR; MALIGNANT GLIAL TUMOR

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 277 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C88025 - NEOPLASM - Neoplasm Type Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C3903 GLIOMA, MIXED, GLIOMA, A malignant neoplasm comprising two or more glial Mixed Glioma MALIGNANT MIXED; MIXED cell types (e.g., astrocytes, ependymal cells, NEUROGLIAL oligodendrocytes). TUMOR; MIXED NEUROGLIAL NEOPLASM; MIXED GLIAL TUMOR; MIXED GLIAL NEOPLASM

C3252 GRANULAR CELL TUMOR, BENIGN A benign neoplasm, comprised of large cells with Benign Granular Cell Tumor BENIGN GRANULAR cytoplasmatic granules, occurring in various CELL TUMOR; organs/tissues. BENIGN GRANULAR CELL NEOPLASM; BENIGN GRANULAR CELL MYOBLASTOM A; MYOBLASTOM A

C4336 GRANULAR CELL TUMOR, MYOBLASTOM A malignant neoplasm, comprised of large cells with Malignant Granular Cell Tumor MALIGNANT A, cytoplasmatic granules, occurring in various MALIGNANT; organs/tissues. MALIGNANT GRANULAR CELL NEOPLASM; MALIGNANT GRANULAR CELL MYOBLASTOM A

C4205 GRANULOSA CELL GRANULOSA A malignant neoplasm of the ovary, originating from Malignant Granulosa Cell Tumor TUMOR, MALIGNANT CELL granulosa cells. NEOPLASM

C3070 GRANULOSA CELL GRANULOSA A neoplasm of the ovary (or testis), originating from Granulosa Cell Tumor TUMOR, UNDETERMINED CELL granulosa cells for which the malignancy status has not NEOPLASM been established.

C27520 HAIR FOLLICLE BENIGN A benign neoplasm that arises from the hair follicle. Benign Hair Follicle Neoplasm NEOPLASM, BENIGN FOLLICULAR NEOPLASM; BENIGN FOLLICULAR TUMOR; BENIGN HAIR FOLLICLE TUMOR

C43310 HAIR FOLLICLE MALIGNANT A malignant neoplasm that arises from the hair Malignant Hair Follicle Neoplasm NEOPLASM, MALIGNANT HAIR follicle. FOLLICLE TUMOR

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 278 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C88025 - NEOPLASM - Neoplasm Type Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C7367 HAIR FOLLICLE HAIR A neoplasm that arises from the hair follicle, for which Hair Follicle Neoplasm NEOPLASM, FOLLICLE the malignancy status has not been established. UNDETERMINED TUMOR; HAIR MATRIX NEOPLASM; HAIR MATRIX TUMOR; NEOPLASM OF HAIR FOLLICLE; NEOPLASM OF THE HAIR FOLLICLE

C3075 HAMARTOMA, BENIGN A benign and excessive tumor-like growth of mature Hamartoma cells and normal tissues which grow in a disorganized pattern.

C40426 HAMARTOMA, A benign hamartomatous tumor composed Lipomatous Hamartoma LIPOMATOUS, BENIGN predominantly of adipose tissue.

C3085 HEMANGIOMA, BENIGN ANGIOMA; A benign vascular neoplasm characterized by the Hemangioma BENIGN formation of capillary-sized or cavernous vascular ANGIOMA; channels. BENIGN HEMANGIOMA

C4300 HEMANGIOPERICYTOMA, A benign neoplasm originating from vascular pericytes Benign Hemangiopericytoma BENIGN (cells in the periphery of vessels).

C4301 HEMANGIOPERICYTOMA, MALIGNANT A malignant neoplasm originating from vascular Malignant Hemangiopericytoma MALIGNANT HEMANGIOPE pericytes (cells in the periphery of vessels). RICYTOMA NOS

C3087 HEMANGIOPERICYTOMA, A neoplasm originating from vascular pericytes (cells Hemangiopericytoma UNDETERMINED in the periphery of vessels), for which the malignancy status has not been established.

C3088 HEMANGIOSARCOMA, HEMANGIOSA A malignant vascular neoplasm arising from Angiosarcoma MALIGNANT RCOMA endothelial cells.

C3728 HEPATOBLASTOMA, HBL; A malignant liver neoplasm composed of immature Hepatoblastoma MALIGNANT PEDIATRIC hepatocytic elements. EMBRYONAL HEPATOMA; PEDIATRIC HEPATOBLAST OMA

C3702 HIBERNOMA, BENIGN BROWN FAT A benign neoplasm of the brown adipose tissue. Hibernoma NEOPLASM; FETAL FAT CELL LIPOMA; BROWN FAT TUMOR

C98708 HISTIOCYTOMA, BENIGN A benign dermal neoplasm comprising of round cells, Benign Histiocytoma resembling histiocytes. The tumor commonly occurs in young dogs and may regress spontaneously.

C3739 HISTIOCYTOMA, FIBROUS, FIBROUS A benign neoplasm composed of a fibroblastic and a Benign Fibrous Histiocytoma BENIGN HISTIOCYTOM histiocytic component. A

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 279 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C88025 - NEOPLASM - Neoplasm Type Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C4247 HISTIOCYTOMA, FIBROUS, MALIGNANT A malignant neoplasm composed of a fibroblastic and Malignant Fibrous Histiocytoma MALIGNANT FIBROUS a histiocytic component. HISTIOCYTOM A OF THE SOFT TISSUE AND BONE; FIBROXANTHO SARCOMA; MALIGNANT FIBROXANTHO MA; MFH; MALIGNANT FIBROUS HISTIOCYTOM A OF SOFT TISSUE AND BONE

C8402 HISTIOCYTOMA, FIBROUS, FIBROHISTIOC A neoplasm composed of a fibroblastic and a Fibrohistiocytic Neoplasm UNDETERMINED YTIC TUMOR histiocytic component, for which the malignancy status has not been established.

C35765 HISTIOCYTOMA, A neoplasm composed of histiocytic cells, for which Histiocytoma UNDETERMINED the malignancy status has not been established.

C80351 ITO CELL TUMOR, BENIGN BENIGN A benign neoplasm of the liver composed of hepatic Benign Ito Cell Tumor SPONGIOTIC stellate cells (Ito cells). PERICYTOMA

C80352 ITO CELL TUMOR, MALIGNANT A malignant neoplasm of the liver composed of Malignant Ito Cell Tumor MALIGNANT SPONGIOTIC hepatic stellate cells (Ito cells). PERICYTOMA

C3146 KERATOACANTHOMA, An epithelial skin neoplasm, composed of squamous Keratoacanthoma UNDETERMINED cells, for which the malignancy status has not been established.

C81854 LEIOMYOBLASTOMA, A benign neoplasm of the gastro-intestinal tract, Benign Epithelioid Cell Type BENIGN originating from smooth muscle cells. Gastrointestinal Stromal Tumor

C81855 LEIOMYOBLASTOMA, A malignant neoplasm of the gastro-intestinal tract, Malignant Epithelioid Cell Type MALIGNANT originating from smooth muscle cells. Gastrointestinal Stromal Tumor

C3486 LEIOMYOBLASTOMA, LEIOMYOBLAS A neoplasm of the gastro-intestinal tract, originating Epithelioid Cell Type UNDETERMINED TOMA; from smooth muscle cells, for which the malignancy Gastrointestinal Stromal Tumor EPITHELIOID status has not been established. CELL TYPE GIST; STOUT'S LEIOMYOBLAS TOMA

C3157 LEIOMYOMA, BENIGN LEIOMYOMAT A benign neoplasm, originating from smooth muscle Leiomyoma OUS cells. NEOPLASM; LEIOMYOMAT OUS TUMOR; FIBROID NEOPLASM; FIBROID TUMOR; FIBROID

C3158 LEIOMYOSARCOMA, LEIOMYOSARC A malignant neoplasm, originating from smooth Leiomyosarcoma MALIGNANT OMAS muscle cells.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 280 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C88025 - NEOPLASM - Neoplasm Type Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C8923 LEUKEMIA, ACUTE DIGUGLIELMO' A progressive, proliferative disease of blood cells, Acute Erythroid Leukemia ERYTHROID, MALIGNANT S DISEASE; originating from immature erythroid cells. DIGUGLIELMO' S SYNDROMA; ERYTHROBLAS TIC LEUKEMIA; ACUTE ERYTHROBLAS TIC LEUKEMIA; DI GUGLIELMO'S DISEASE; M6 ACUTE MYELOID LEUKEMIA; DI GUGLIELMO DISEASE; FAB M6

C3167 LEUKEMIA, ACUTE LYMPHOBLAS A progressive, proliferative disease of blood cells, Acute Lymphoblastic Leukemia LYMPHOBLASTIC, TIC LEUKEMIA; originating from immature lymphoid cells. MALIGNANT ALL - ACUTE LYMPHOCYTIC LEUKEMIA; ACUTE LYMPHOID LEUKEMIA; PRECURSOR CELL LYMPHOBLAS TIC LEUKEMIA; ALL; PRECURSOR LYMPHOBLASI C LEUKEMIA; ACUTE LYMPHOGENO US LEUKEMIA; ACUTE LYMPHOCYTIC LEUKEMIAS; ACUTE LYMPHOCYTIC LEUKAEMIA

C3170 LEUKEMIA, ACUTE ACUTE A progressive, proliferative disease of blood cells, Acute Megakaryoblastic Leukemia MEGAKARYOCYTIC, MEGAKARYOC originating from immature megakaryocytes. MALIGNANT YTIC LEUKEMIA; ACUTE MEGAKARYOB LASTIC LEUKEMIA (FAB TYPE M7); FAB M7; ACUTE M7 MYELOID LEUKEMIA

C4861 LEUKEMIA, ACUTE ACUTE A progressive, proliferative disease of blood cells, Acute Monocytic Leukemia MONOCYTIC, MALIGNANT MONOCYTIC originating from immature monocytes. LEUKEMIA (FAB M5B); MONOCYTIC LEUKEMIA

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 281 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C88025 - NEOPLASM - Neoplasm Type Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C3172 LEUKEMIA, LEUKEMIA A progressive, proliferative disease of blood cells, Myeloid Leukemia GRANULOCYTIC, GRANULOCYTI originating from immature granulocytes. MALIGNANT C; LEUKEMIA MYELOID; NON-LYMPHO BLASTIC LEUKEMIA; MYELOCYTIC LEUKEMIA; NON-LYMPHO CYTIC LEUKEMIA; MYELOGENOU S LEUKEMIA

C4664 LEUKEMIA, LARGE T-GAMMA A progressive, proliferative disease of blood cells T-Cell Large Granular Lymphocyte GRANULAR LYMPHOPROLI which are large and granular, originating from Leukemia LYMPHOCYTIC, FERATIVE lymphoid cells. MALIGNANT DISORDER; LARGE CELL GRANULAR LYMPHOID LEUKEMIA; T-CELL LARGE GRANULAR LYMPHOCYTIC LEUKEMIA; LGLL; TGAMMA LARGE GRANULAR LYMPHOCYTE LEUKEMIA; T GAMMA LYMPHOPROLI FERATIVE DISORDER; LARGE GRANULAR LYMPHOCYTO SIS; LARGE GRANULAR LYMPHOCYTIC LEUKEMIA; LARGE CELL GRANULAR LYMPHOGENO US LEUKEMIA

C7539 LEUKEMIA, LYMPHOGENO A progressive, proliferative disease of blood cells, Lymphoid Leukemia LYMPHOCYTIC, US LEUKEMIA; originating from lymphoid cells. MALIGNANT LYMPHOCYTIC LEUKEMIA

C3161 LEUKEMIA, MALIGNANT LEUKEMIA A progressive, proliferative disease of blood cells, Leukemia NOS; originating from myeloid or lymphoid stem cells. LEUKEMIAS, GENERAL; LEUKEMIAS; BLOOD (LEUKEMIA)

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 282 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C88025 - NEOPLASM - Neoplasm Type Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C4212 LEYDIG CELL TUMOR, ADENOMA, A benign neoplasm of the testis originating from Benign Leydig Cell Tumor BENIGN INTERSTITIAL; interstitial (Leydig) cells. BENIGN INTERSTITIAL CELL NEOPLASM; BENIGN INTERSTITIAL CELL TUMOR; BENIGN LEYDIG CELL NEOPLASM

C4213 LEYDIG CELL TUMOR, MALIGNANT A malignant neoplasm of the testis originating from Malignant Leydig Cell Tumor MALIGNANT INTERSTITIAL interstitial (Leydig) cells. CELL TUMOR; MALIGNANT LEYDIG CELL NEOPLASM; MALIGNANT INTERSTITIAL CELL NEOPLASM

C3188 LEYDIG CELL TUMOR, LEYDIG CELL A neoplasm of the testis originating from interstitial Leydig Cell Tumor UNDETERMINED TUMOR; (Leydig) cells, for which the malignancy status has not LEYDIG CELL been established. NEOPLASM; INTERSTITIAL CELL NEOPLASM; INTERSTITIAL CELL TUMOR

C3192 LIPOMA, BENIGN A benign neoplasm composed of adipose tissue. Lipoma

C3194 LIPOSARCOMA, MALIGNANT A malignant neoplasm composed of adipose tissue. Liposarcoma MALIGNANT HIBERNOMA

C3202 LUTEOMA, BENIGN LUTEOMA; A benign neoplasm of the ovary, composed of Ovarian Stromal Luteoma LUTEINOMA; leuteinized granulosa-theca cells. LUTEAL CELL TUMOR; LUTEAL CELL NEOPLASM; OVARIAN STROMA LUTEOMA

C8965 LYMPHANGIOMA, BENIGN A benign neoplasm arising from the lymphatics. Lymphangioma

C3205 LYMPHANGIOSARCOMA, MALIGNANT A malignant neoplasm arising from the endothelial Lymphangiosarcoma MALIGNANT LYMPHANGIO cells of the lymphatic vessels. ENDOTHELIOM A; LYMPHANGIO ENDOTHELIAL SARCOMA

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 283 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C88025 - NEOPLASM - Neoplasm Type Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C3209 LYMPHOMA, FOLLICULAR, LYMPHOMA, A neoplasm of lymphoid cells which has at least a Follicular Lymphoma MALIGNANT FOLLICULAR partial follicular pattern. CENTRE CELL; FOLLICULAR CENTRE CELL LYMPHOMA; FOLLICLE CENTER LYMPHOMA; FOLLICULAR NON-HODGKIN LYMPHOMA; FOLLICULAR NON-HODGKIN 'S LYMPHOMA

C35382 LYMPHOMA, HISTIOCYTIC, LYMPHOMA, A malignant neoplasm of large lymphocytes, which True Histiocytic Lymphoma MALIGNANT LARGE CELL, resemble histiocytes. MALIGNANT

C3461 LYMPHOMA, LYMPHOMA, A malignant neoplasm composed of immunoblasts Immunoblastic Lymphoma IMMUNOBLASTIC, LYMPHOCYTIC (large B cells). MALIGNANT , MALIGNANT

C9360 LYMPHOMA, PRECURSOR A malignant neoplasm composed of lymphoblasts Lymphoblastic Lymphoma LYMPHOBLASTIC, CELL (lymphoid precursor cells). MALIGNANT LYMPHOBLAS TIC LYMPHOMA; PRECURSOR LYMPHOBLAS TIC LYMPHOMA

C3212 LYMPHOMA, LYMPHOMA, A malignant neoplasm composed of lymphocytes Lymphoplasmacytic Lymphoma LYMPHOPLASMACYTIC, PLASMACYTIC; (B-cells), lymphoplasmacytoid cells, and plasma cells. MALIGNANT IMMUNOCYTO MA, LYMPHOPLAS MACYTIC TYPE; LYMPHOPLAS MACYTOID LYMPHOMA

C3208 LYMPHOMA, MALIGNANT LYMPHOMA, A malignant neoplasm composed of lymphocytes of B- Lymphoma PLEOMORPHIC or T/NK-cell phenotype. , MALIGNANT; LYMPHOMA (HODGKIN AND NON-HODGKIN ); LYMPHOMA (HODGKIN'S AND NON-HODGKIN 'S); MALIGNANT LYMPHOMA

C3463 LYMPHOMA, MIXED, DIFFUSE A malignant neoplasm composed of a mixed Diffuse Mixed Cell Lymphoma MALIGNANT MIXED LARGE lymphocyte population. AND SMALL CELL LYMPHOMA

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 284 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C88025 - NEOPLASM - Neoplasm Type Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C7540 LYMPHOMA, SMALL SMALL B-CELL A malignant neoplasm composed of small Small Lymphocytic Lymphoma LYMPHOCYTIC, LYMPHOCYTIC lymphocytes. MALIGNANT LYMPHOMA; SLL; B-CELL SMALL LYMPHOCYTIC LYMPHOMA

C26919 LYMPHOSARCOMA, An antiquated term referring to a malignant lymphoma Lymphosarcoma MALIGNANT that is diffused and composed of small and large lymphocytes.

C3217 MAST CELL TUMOR, A benign neoplasm composed of mast cells. Benign Mastocytoma BENIGN

C8991 MAST CELL TUMOR, A malignant neoplasm composed of mast cells. Malignant Mastocytosis MALIGNANT

C9295 MAST CELL TUMOR, MAST CELL A neoplasm composed of mast cells, for which the Mast Cell Neoplasm UNDETERMINED PROLIFERATIV malignancy status has not been determined. E DISEASE; TUMOR OF MAST CELLS; NEOPLASM OF MAST CELLS; MASTOCYTOSI S; NEOPLASM OF THE MAST CELLS; MAST CELL TUMOR; TUMOR OF THE MAST CELLS

C3222 MEDULLOBLASTOMA, MEDULLOBLA A malignant, invasive embryonal neoplasm arising Medulloblastoma MALIGNANT STOMAS from the cerebellum.

C98709 MELANOCYTOMA, BENIGN A benign neoplasm or hamartoma composed of Benign Melanocytoma melanocytes.

C3802 MELANOMA, A malignant neoplasm composed of melanocytes, Amelanotic Melanoma AMELANOTIC, which lack melanin. MALIGNANT

C3224 MELANOMA, MALIGNANT MALIGNANT A malignant neoplasm composed of melanocytes. Melanoma MELANOMA

C7712 MELANOMA, UVEAL, MELANOMA A malignant neoplasm of the uvea composed of Uveal Melanoma MALIGNANT OF UVEA; melanocytes. MELANOMA OF THE UVEA; INTRAOCULAR MELANOMA

C4051 MENINGIOMA, ANAPLASTIC A malignant neoplasm of the meninges, exhibiting Anaplastic (Malignant) Meningioma ANAPLASTIC, MALIGNANT MENINGIOMA; poor differentiation (anaplasia). MALIGNANT MENINGIOMA; MENINGIOMA, MALIGNANT

C4055 MENINGIOMA, BENIGN MENINGIOMA, A benign neoplasm of the meninges. Benign Meningioma BENIGN

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 285 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C88025 - NEOPLASM - Neoplasm Type Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C38938 MENINGIOMA, GRADE III A malignant neoplasm of the meninges. Grade III Meningioma MALIGNANT MENINGIOMA; GRADE 3 MENINGIOMA; WHO GRADE III MENINGIOMA

C3230 MENINGIOMA, A neoplasm of the meninges, for which the status of Meningioma UNDETERMINED malignancy has not been determined.

C4267 MESENCHYMAL TUMOR, BENIGN A benign soft-tissue neoplasm comprising two or Benign Mesenchymoma BENIGN CONNECTIVE more non-fibroblastic mesenchymal lines of AND SOFT differentiation. TISSUE NEOPLASM; BENIGN CONNECTIVE AND SOFT TISSUE TUMOR; BENIGN MESENCHYMA L CELL NEOPLASM; BENIGN NEOPLASM OF THE SOFT TISSUE AND BONE; BENIGN TUMOR OF THE SOFT TISSUE AND BONE

C3762 MESOTHELIOMA, BENIGN ADENOMATOI A benign neoplasm arising from mesothelial cells. Adenomatoid Tumor D TUMOR, BENIGN; BENIGN MESOTHELIOM A; MESOTHELIOM A, BENIGN; BENIGN NEOPLASM OF MESOTHELIUM ; BENIGN MESOTHELIAL NEOPLASM; BENIGN TUMOR OF MESOTHELIUM ; BENIGN MESOTHELIAL TUMOR; BENIGN LOCALIZED EPITHELIAL MESOTHELIOM A; BENIGN TUMOR OF THE MESOTHELIUM ; BENIGN NEOPLASM OF THE MESOTHELIUM

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 286 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C88025 - NEOPLASM - Neoplasm Type Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C4456 MESOTHELIOMA, MALIGNANT A malignant neoplasm originating from mesothelial Malignant Mesothelioma MALIGNANT TUMOR OF cells of the pleura or peritoneum. MESOTHELIUM ; MALIGNANT NEOPLASM OF THE MESOTHELIUM ; MALIGNANT MESOTHELIAL TUMOR; MALIGNANT NEOPLASM OF MESOTHELIUM ; MALIGNANT MESOTHELIAL NEOPLASM; MALIGNANT TUMOR OF THE MESOTHELIUM

C3234 MESOTHELIOMA, A neoplasm originating from mesothelial cells of the Mesothelioma UNDETERMINED pleura or peritoneum, for which the malignancy status has not been established.

C4050 MIXED GLIOMA, BENIGN A benign neoplasm of the central nervous system with Oligoastrocytoma an astrocytic and oligodendrocytic component.

C8602 MIXED TUMOR, BENIGN A benign neoplasm composed of epithelial and/or Pleomorphic Adenoma myoepithelial cells and a mesenchymal component.

C3729 MIXED TUMOR, MALIGNANT A malignant neoplasm composed of epithelial and/or Malignant Mixed Neoplasm MALIGNANT MIXED TUMOR myoepithelial cells and a mesenchymal component. A general term for which the transformed cell types have not been specified.

C6930 MIXED TUMOR, TUMOR, A neoplasm composed of an epithelial component Mixed Neoplasm UNDETERMINED MIXED; MIXED and/or a mesenchymal component, for which the TUMOR malignancy status has not been established. A general term for which the transformed cell types have not been specified.

C8975 MUELLERIAN TUMOR, MALIGNANT A malignant neoplasm of the female reproductive Malignant Mixed Mesodermal MIXED, MALIGNANT MIXED system (mostly uterus and ovaries) originating from (Mullerian) Tumor MESODERMAL the Muellerian ducts and composed of carcinomatous TUMOR; and sarcomatous elements. MALIGNANT MIXED MULLERIAN TUMOR; MMMT

C3736 MYELOLIPOMA, BENIGN MYELIPOMA A benign tumor of the adrenal gland composed of Adrenal Gland Myelolipoma adipocytes and hematopoietic/lymphoid cells.

C3242 MYELOMA, PLASMA CELL, MYELOMA; A malignant neoplasm of the bone marrow composed Plasma Cell Myeloma MALIGNANT MULTIPLE of plasma cells. MYELOMA

C7442 MYOEPITHELIOMA, A benign neoplasm composed of myoepithelial cells. Benign Myoepithelioma BENIGN

C7596 MYOEPITHELIOMA, MYOEPITHELI A malignant neoplasm composed of myoepithelial Malignant Myoepithelioma MALIGNANT AL cells. CARCINOMA; MALIGNANT MYOEPITHELI OMA

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 287 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C88025 - NEOPLASM - Neoplasm Type Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C6577 MYXOMA, BENIGN A benign soft tissue neoplasm with a myxoid stroma Myxoma formation.

C3255 MYXOSARCOMA, A malignant soft tissue neoplasm with a myxoid Myxosarcoma MALIGNANT stroma formation.

C4743 NEOPLASM, BASAL CELL, BENIGN BASAL A benign neoplasm composed of basal cells. Benign Basal Cell Neoplasm BENIGN CELL TUMOR

C7586 NEOPLASM, BASAL CELL, A malignant neoplasm composed of basal cells. Malignant Basal Cell Neoplasm MALIGNANT

C3677 NEOPLASM, BENIGN BENIGN A general term used to describe autonomous growth of Benign Neoplasm TUMOR; tissue where the originating cell type has not been BENIGN characterized. The term benign indicates the absence UNCLASSIFIAB of morphologic features associated with malignancy LE TUMOR (for instance severe atypia, nuclear pleomorphism, tumor cell necrosis, and abnormal mitoses).

C9305 NEOPLASM, MALIGNANT MALIGNANCY; A general term for autonomous tissue growth Malignant Neoplasm CA; CANCER; exhibiting morphologic features of malignancy (e.g. MALIGNANT severe atypia, nuclear pleomorphism, tumor cell TUMOR necrosis, abnormal mitoses, tissue invasiveness) and for which the transformed cell type has not been specifically identified.

C3262 NEOPLASM, A general term for autonomous tissue growth in which Neoplasm UNDETERMINED the malignancy status has not been established and for which the transformed cell type has not been specifically identified.

C40407 NEPHROBLASTOMA, EMBRYONAL A malignant embryonal neoplasm of the kidney. Renal Wilms Tumor MALIGNANT NEPHROMA; NEPHROBLAST OMA; WILMS TUMOR OF THE KIDNEY; RENAL WILMS' TUMOR; WILMS' TUMOR OF THE KIDNEY

C3809 NEURAL CREST TUMOR, NEUROENDOC A neoplasm composed of cells of neuroendocrine Neuroendocrine Neoplasm UNDETERMINED RINE TUMOR origin for which the malignancy status has not been NOS; established. NEUROENDOC RINE TUMOR

C3270 NEUROBLASTOMA, NEUROBLASTO A malignant neoplasm composed of neuroblastic cells. Neuroblastoma MALIGNANT MA (SCHWANNIAN STROMA-POOR )

C3789 NEUROBLASTOMA, ESTHESIONEU A malignant neoplasm of the olfactory receptor cells, Olfactory Neuroblastoma OLFACTORY, MALIGNANT ROBLASTOMA; composed of neuroblastic cells. OLFACTORY ESTHESIONEU ROBLASTOMA; ESTHESIONEU ROBLASTOMA; ESTHESIONEU ROEPITHELIO MA; OLFACTORY NEUROEPITHE LIOMA

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 288 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C88025 - NEOPLASM - Neoplasm Type Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C3272 NEUROFIBROMA, BENIGN An intraneural or extraneural neoplasm arising from Neurofibroma nerve tissues and neural sheaths, composed of perineurial-like fibroblasts and Schwann cells.

C3059 NEUROGLIAL TUMOR, GLIOMA; A neoplasm of the central nervous system composed Neuroglial Tumor UNDETERMINED NEOPLASM OF of glial cells (astrocytes, oligodendrocytes, ependymal THE cells), for which the malignancy status has not been NEUROGLIA; determined. NEUROGLIAL NEOPLASMS; TUMOR OF THE NEUROGLIA; TUMORS OF NEUROGLIA; TUMOR OF NEUROGLIA; NEOPLASMS OF NEUROGLIA; GLIAL NEOPLASM; GLIAL TUMOR; GLIOMA; NEOPLASM OF NEUROGLIA; NEUROGLIAL NEOPLASM

C4306 ODONTOGENIC TUMOR, BENIGN A benign neoplasm arising from tooth-forming tissues. Benign Odontogenic Neoplasm BENIGN ODONTOGENIC TUMOR

C3286 ODONTOGENIC TUMOR, ODONTOMA, A neoplasm arising from tooth-forming tissues, for Odontogenic Neoplasm UNDETERMINED UNDETERMINE which the malignancy status has not been established. D; ODONTOGENIC TUMOR

C3710 ODONTOMA, AMELOBLASTI A benign neoplasm arising from tooth-forming tissues Ameloblastic Fibro-Odontoma AMELOBLASTIC, BENIGN C with-enamel organ differentiation (but without enamel FIBROODONTO formation). MA; FIBROAMELOB LASTIC ODONTOMA

C7492 ODONTOMA, A malignant neoplasm arising from tooth-forming Ameloblastic Carcinoma AMELOBLASTIC, tissues with-enamel organ differentiation (but without MALIGNANT enamel formation).

C3287 ODONTOMA, BENIGN FIBROODONTO A benign neoplasm of tooth origin. Odontoma MA; FIBRO-ODONT OMA

C4812 ODONTOMA, MALIGNANT ODONTOGENIC A malignant neoplasm of tooth origin. Malignant Odontogenic Neoplasm CARCINOMA; MALIGNANT ODONTOGENIC TUMOR; ODONTOGENIC CARCINOSARC OMA

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 289 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C88025 - NEOPLASM - Neoplasm Type Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C4326 OLIGODENDROGLIOMA, WHO GRADE III A malignant neoplasm of the central nervous system Anaplastic Oligodendroglioma ANAPLASTIC, MALIGNANT OLIGODENDR arising from oligodendrocytes, exhibiting poor OGLIAL differentiation (anaplasia). NEOPLASM; OLIGODENDR OGLIOMA; MALIGNANT; MALIGNANT OLIGODENDR OGLIOMA; WHO GRADE III OLIGODENDR OGLIAL TUMOR; UNDIFFERENTI ATED OLIGODENDR OGLIOMA

C3288 OLIGODENDROGLIOMA, WELL A neoplasm of the central nervous system arising from Oligodendroglioma UNDETERMINED DIFFERENTIAT oligodendrocytes, for which the malignancy status has ED not been determined. OLIGODENDR OGLIOMA; WELL DIFFERENTIAT ED OLIGODENDR OGLIAL TUMOR; WHO GRADE II OLIGODENDR OGLIAL TUMOR; WHO GRADE II OLIGODENDR OGLIAL NEOPLASM

C7072 ONCOCYTOMA, BENIGN ONCOCYTOMA A benign neoplasm composed of large cells with Oncocytic Neoplasm ; ONCOCYTIC abundant eosinophilic granular cytoplasm (oncocytes). TUMOR

C3679 ONCOCYTOMA, HURTHLE A malignant neoplasm composed of large epithelial Oxyphilic Adenocarcinoma MALIGNANT CELL cells with abundant granular eosinophilic cytoplasm CARCINOMA; (oncocytes). HURTHLE CELL ADENOCARCIN OMA; ONCOCYTIC ADENOCARCIN OMA; ONCOCYTIC CARCINOMA

C3294 OSTEOBLASTOMA, GIANT A benign neoplasm of bone, characterized by the Osteoblastoma BENIGN OSTEOID formation of osteoid tissue and large osteoblast-like OSTEOMA; cells. OSSIFYING GIANT CELL TUMOR

C3295 OSTEOCHONDROMA, A benign cartiliginous neoplasm arising from the Osteochondroma BENIGN metaphysis of bone.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 290 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C88025 - NEOPLASM - Neoplasm Type Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C7155 OSTEOCHONDROSARCOM PRIMARY A malignant cartiliginous neoplasm of bone. Conventional Chondrosarcoma A, MALIGNANT CHONDROSAR COMA; CONVENTIONA L CHONDROSAR COMA OF BONE; PRIMARY CHONDROSAR COMA OF THE BONE; PRIMARY CHONDROSAR COMA OF BONE; PRIMARY BONE CHONDROSAR COMA

C4304 OSTEOCLASTOMA, GIANT CELL A malignant neoplasm of bone comprised of Malignant Giant Cell Tumor of Bone MALIGNANT SARCOMA OF osteoclast-like giant cells and mononuclear cells. THE BONE; GIANT CELL SARCOMA OF BONE; GIANT CELL BONE SARCOMA; DEDIFFERENTI ATED GIANT CELL TUMOR

C3738 OSTEOCLASTOMA, GIANT CELL A neoplasm of bone comprised of osteoclast-like giant Giant Cell Tumor of Bone UNDETERMINED NEOPLASM OF cells and mononuclear cells, for which the malignancy BONE; BONE status has not been established. GIANT CELL TUMOR; BONE GIANT CELL NEOPLASM

C3740 OSTEOFIBROMA, BENIGN OSTEOFIBROM A benign neoplasm characterized by osteolysis and the Bone Desmoplastic Fibroma A, BONE; presence of a rich collagenous stroma and spindle DESMOID cells. TUMOR OF BONE; DESMOPLASTI C FIBROMA OF BONE; DESMOPLASTI C FIBROMA OF THE BONE; DESMOPLASTI C FIBROMA; OSSEOUS DESMOPLASTI C FIBROMA

C3296 OSTEOMA, BENIGN A benign well-differentiated neoplasm of bone. Osteoma

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 291 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C88025 - NEOPLASM - Neoplasm Type Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C8810 OSTEOSARCOMA, OSSIFYING A malignant bone-forming neoplasm, arising in tissue Extraskeletal Osteosarcoma EXTRASKELETAL, SARCOMA; other than bone. MALIGNANT EXTRAOSSEOU S OSTEOSARCO MA; EXTRASKELET AL OSTEOGENIC SARCOMA; SOFT TISSUE OSTEOSARCO MA

C9145 OSTEOSARCOMA, OSTEOGENIC A malignant neoplasm usually arising from bone. Osteosarcoma MALIGNANT SARCOMA; OSTEOGENIC SARCOMA

C6803 OVARIAN SEX SEX CORD A benign neoplasm of the ovary, originating from the Benign Ovarian Sex Cord-Stromal CORD-STROMAL TUMOR, STROMAL sex-cord stroma. Tumor BENIGN TUMOR, BENIGN; BENIGN SEX CORD-STROMA L NEOPLASM OF THE OVARY; BENIGN SEX CORD-STROMA L TUMOR OF THE OVARY; BENIGN OVARIAN SEX CORD-STROMA L NEOPLASM; BENIGN SEX CORD-STROMA L TUMOR OF OVARY; BENIGN SEX CORD-STROMA L NEOPLASM OF OVARY

C7440 PAPILLOMA, BENIGN A benign epithelial neoplasm that projects above the Papilloma surrounding epithelial surface.

C3698 PAPILLOMA, CHOROID PAPILLOMA OF A benign neoplasm of the choroid plexus of the central Choroid Plexus Papilloma PLEXUS, BENIGN CHOROID nervous system. PLEXUS; PAPILLOMA OF THE CHOROID PLEXUS

C3712 PAPILLOMA, SQUAMOUS EPIDERMOID A benign epithelial neoplasm characterized by a Squamous Papilloma CELL, BENIGN PAPILLOMA; papillary growth pattern and a proliferation of EPIDERMOID neoplastic squamous cells. CELL PAPILLOMA; KERATOTIC PAPILLOMA; SQUAMOUS CELL PAPILLOMA

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 292 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C88025 - NEOPLASM - Neoplasm Type Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C4115 PAPILLOMA, TRANSITIONAL A benign papillary neoplasm composed of transitional Transitional Cell Papilloma TRANSITIONAL CELL, PAPILLOMA cells. BENIGN

C48314 PARAGANGLIOMA, NEURAL A benign neoplasm arising from paraganglia located Benign Paraganglioma BENIGN CREST TUMOR, along nerves composed of neoplastic neuroectodermal BENIGN; chromaffin cells. NEUROENDOC RINE TUMOR, BENIGN; BENIGN PARAGANGLIO NIC NEOPLASM; BENIGN NEUROENDOC RINE CELL TUMOR

C8559 PARAGANGLIOMA, MALIGNANT A malignant neoplasm arising from paraganglia located Malignant Paraganglioma MALIGNANT TUMOR OF THE along nerves composed of neoplastic neuroectodermal PARAGANGLIO chromaffin cells. N; MALIGNANT TUMOR OF PARAGANGLIO N; MALIGNANT PARAGANGLIO NIC NEOPLASM; MALIGNANT PARAGANGLIO NIC TUMOR; MALIGNANT NEOPLASM OF PARAGANGLIO N; MALIGNANT PARAGANGLIO N NEOPLASM; MALIGNANT PARAGANGLIO N TUMOR; PARAGANGLIO N NEOPLASM; MALIGNANT; MALIGNANT NEOPLASM OF THE PARAGANGLIO N

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 293 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C88025 - NEOPLASM - Neoplasm Type Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C3308 PARAGANGLIOMA, PARAGANGLIO A neoplasm arising from paraganglia located along Paraganglioma UNDETERMINED N NEOPLASM; nerves composed of neoplastic neuroectodermal NEOPLASM OF chromaffin cells, for which the malignancy status has PARAGANGLIO not been established. N; TUMOR OF THE PARAGANGLIO N; PARAGANGLIO N TUMOR; TUMOR OF PARAGANGLIO N; PARAGANGLIO NIC NEOPLASM; PARAGANGLIO NIC TUMOR; NEOPLASM OF THE PARAGANGLIO N

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 294 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C88025 - NEOPLASM - Neoplasm Type Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C3798 PERIPHERAL NERVE MALIGNANT A malignant neoplasm, originating from the sheaths of Malignant Peripheral Nerve Sheath SHEATH TUMOR, NEURILEMMO the peripheral nerve. Tumor MALIGNANT MA; MALIGNANT SCHWANNOM A; NEUROFIBROS ARCOMA, MALIGNANT; MALIGNANT NEOPLASM OF PERIPHERAL NERVE SHEATH; MALIGNANT NEOPLASM OF THE PERIPHERAL NERVE SHEATH; MALIGNANT NEURILEMMO MA; MALIGNANT NEURILEMOM A; MALIGNANT PERIPHERAL NERVE SHEATH NEOPLASM; MALIGNANT PERIPHERAL NERVE SHEATH TUMOUR; MALIGNANT TUMOR OF PERIPHERAL NERVE SHEATH; MALIGNANT TUMOR OF THE PERIPHERAL NERVE SHEATH; MPNST

C48305 PHEOCHROMOCYTOMA, A benign neoplasm of the adrenal gland medulla. Benign Adrenal Gland BENIGN Pheochromocytoma

C92181 PHEOCHROMOCYTOMA, A benign neoplasm of the adrenal gland medulla, Benign Adrenal Gland Composite COMPLEX, BENIGN composed of medullary and neuroectodermal Pheochromocytoma components.

C48306 PHEOCHROMOCYTOMA, A neoplasm of the adrenal gland medulla, composed of Adrenal Gland Composite COMPLEX, medullary and neuroectodermal components, for Pheochromocytoma UNDETERMINED which the malignancy status has not been established.

C92184 PHEOCHROMOCYTOMA, A malignant neoplasm of the adrenal gland medulla, Malignant Adrenal Gland Composite COMPLEX,MALIGNANT composed of medullary and neuroectodermal Pheochromocytoma components.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 295 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C88025 - NEOPLASM - Neoplasm Type Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C4220 PHEOCHROMOCYTOMA, MALIGNANT A malignant neoplasm of the adrenal gland medulla. Malignant Adrenal Gland MALIGNANT PHEOCHROMO Pheochromocytoma CYTOMA; MALIGNANT ADRENAL MEDULLARY PHEOCHROMO CYTOMA; MALIGNANT ADRENAL PHEOCHROMO CYTOMA; MALIGNANT ADRENAL GLAND PARAGANGLIO MA; MALIGNANT ADRENAL GLAND CHROMAFFINO MA; MALIGNANT ADRENAL GLAND CHROMAFFIN NEOPLASM; MALIGNANT ADRENAL GLAND CHROMAFFIN TUMOR; MALIGNANT ADRENAL GLAND CHROMAFFIN PARAGANGLIO MA; PHEOCHROMO BLASTOMA; MALIGNANT ADRENAL MEDULLARY PARAGANGLIO MA

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 296 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C88025 - NEOPLASM - Neoplasm Type Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C3326 PHEOCHROMOCYTOMA, ADRENAL A neoplasm of the adrenal gland medulla, for which the Adrenal Gland Pheochromocytoma UNDETERMINED PHEOCHROMO malignancy status has not been established. CYTOMA; CHROMAFFIN PARAGANGLIO MA OF THE ADRENAL GLAND; INTRAADRENA L PARAGANGLIO MA; ADRENAL MEDULLARY PARAGANGLIO MA; ADRENAL GLAND PARAGANGLIO MA; ADRENAL MEDULLARY PHEOCHROMO CYTOMA; PCC; ADRENAL GLAND CHROMAFFIN PARAGANGLIO MA; PHAEOCHROM OCYTOMA; ADRENAL GLAND CHROMAFFINO MA; PHEOCHROMO CYTOMA

C7368 PILOMATRIXOMA, BENIGN BENIGN A benign adnexal neoplasm arising from hair-bearing Pilomatricoma PILOMATRICO skin surfaces. MA; PILOMATRIXO MA; CALCIFYING EPITHERLIOM A OF MALHERBE; BENIGN PILOMATRIXO MA; BENIGN HAIR FOLLICLE NEOPLASM

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 297 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C88025 - NEOPLASM - Neoplasm Type Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C9344 PINEOBLASTOMA, PINEAL GLAND A poorly differentiated malignant embryonal neoplasm Pineoblastoma MALIGNANT PNET; PINEAL arising from the pineal region of the brain. GLAND PRIMITIVE NEUROECTOD ERMAL NEOPLASM; PINEAL GLAND PRIMITIVE NEUROECTOD ERMAL TUMOR; PINEAL PNET; PINEAL PRIMITIVE NEUROECTOD ERMAL NEOPLASM; PINEAL PRIMITIVE NEUROECTOD ERMAL TUMOR; PNET OF PINEAL GLAND; PNET OF THE PINEAL GLAND; PRIMITIVE NEUROECTOD ERMAL NEOPLASM OF PINEAL GLAND; PRIMITIVE NEUROECTOD ERMAL NEOPLASM OF THE PINEAL GLAND; PRIMITIVE NEUROECTOD ERMAL TUMOR OF PINEAL GLAND; PRIMITIVE NEUROECTOD ERMAL TUMOR OF THE PINEAL GLAND

C6966 PINEOCYTOMA, BENIGN PINEALOMA; A benign neoplasm of the brain arising from the pineal Pineocytoma BENIGN gland. PINEALOMA

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 298 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C88025 - NEOPLASM - Neoplasm Type Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C7157 PITUICYTOMA, BENIGN POSTERIOR A neoplasm arising from the posterior lobe of the Posterior Pituitary Gland Neoplasm PITUITARY pituitary gland. TUMOR; POSTERIOR PITUITARY GLAND TUMOR; NEUROHYPOP HYSIS NEOPLASM; NEUROHYPOP HYSIS TUMOR; POSTERIOR PITUITARY NEOPLASM

C4665 PLASMA CELL TUMOR, PLASMACYTIC A malignant neoplasm composed of plasma cells. Plasma Cell Neoplasm MALIGNANT TUMOR; PLASMA CELL DYSCRASIA; PLASMACYTIC TUMOR; PLASMA CELL TUMOR; PLASMACYTIC NEOPLASM

C3764 POLYP, ADENOMATOUS, POLYPOID A neoplasm, originating from glandular epithelium, Adenomatous Polyp UNDETERMINED ADENOMA exhibiting polypoid growth, for which the malignancy status has not been determined.

C6433 POLYP, ENDOMETRIAL POLYP, A benign polypoid neoplasm of the endometrium Endometrial Polyp STROMAL, BENIGN STROMAL; projecting into the endometrial cavity. POLYP OF THE ENDOMETRIU M; ENDOMETRIAL STROMAL POLYP; POLYP OF ENDOMETRIU M; ADENOMA; ENDOMETRIAL ; GLANDULAR ENDOMETRIAL POLYP; ENDOMETRIAL ADENOMA

C5680 POLYP, INFLAMMATORY, INFLAMMATO A non-neoplastic inflammatory polypoid lesion in the Colorectal Inflammatory Polyp BENIGN RY POLYP OF colon and rectum. THE LARGE BOWEL; LARGE BOWEL INFLAMMATO RY POLYP; INFLAMMATO RY POLY OF LARGE BOWEL

C3340 POLYP, UNDETERMINED A protruding growth attached to the underlying tissue Polyp by a broad base or a thin stalk, which can be either inflammatory, hamartomatous, or neoplastic.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 299 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C88025 - NEOPLASM - Neoplasm Type Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C3664 POLYP, VAGINAL, BENIGN POLYP OF THE A benign polypoid growth arising from the vaginal Vaginal Polyp VAGINA; wall. POLYP OF VAGINA

C4684 RETICULOSIS, MALIGNANT ANGIOCENTRI A malignant lymphoid neoplasm composed of Nasal Type Extranodal NK/T-Cell C T-CELL EBV-positive NK/T cells arranged in an angiocentric Lymphoma LYMPHOMA pattern.

C7541 RETINOBLASTOMA, RB A malignant neoplasm originating in the nuclear layer Retinoblastoma MALIGNANT of the retina.

C3358 RHABDOMYOMA, BENIGN A benign neoplasm arising from skeletal muscle, Rhabdomyoma characterized by the presence of rhabdomyoblasts.

C3359 RHABDOMYOSARCOMA, A malignant mesenchymal neoplasm arising from Rhabdomyosarcoma MALIGNANT skeletal muscle.

C35815 SARCOMA, A malignant neoplasm composed of myeloblasts, Granulocytic Sarcoma GRANULOCYTIC, neutrophils and neutrophil precursors. MALIGNANT

C27349 SARCOMA, HISTIOCYTIC, A malignant neoplasm composed of cells resembling Histiocytic Sarcoma MALIGNANT histiocytes.

C8312 SARCOMA, SARCOMA, A malignant mesenchymal neoplasm arising from the Leptomeningeal Sarcoma LEPTOMENINGEAL, MENINGEAL; leptomeninges. MALIGNANT SARCOMA OF LEPTOMENING ES; SARCOMA OF THE LEPTOMENING ES

C9118 SARCOMA, MALIGNANT SARCOMA OF A malignant mesenchymal neoplasm. A general term Sarcoma SOFT TISSUE for which the transformed cell type has not been AND BONE; specified. SARCOMA OF THE SOFT TISSUE AND BONE; SARCOMA; MESENCHYMA L TUMOR, MALIGNANT

C3520 SARCOMA, MYELOID, CHLOROMA; A malignant neoplasm composed of myeloblasts or Myeloid Sarcoma MALIGNANT EXTRAMEDUL immature myeloid cells. It occurs in extramedullary LARY sites or the bone. MYELOID TUMOR

C3400 SARCOMA, SYNOVIAL, SS A malignant neoplasm that usually arises in the Synovial Sarcoma MALIGNANT synovial membranes of the joints and the synovial cells of the tendons and bursae.

C3269 SCHWANNOMA, BENIGN NEURILEMMO A benign neoplasm of the peripheral nervous system Schwannoma MA; composed of well-differentiated Schwann cells. SCHWANNOM A; NEURINOMA; SCHWANNOM A (WHO GRADE I)

C9309 SEMINOMA, MALIGNANT SEMINOMA, A malignant germ cell neoplasm of the testis. Seminoma PURE; SEMINOMA

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 300 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C88025 - NEOPLASM - Neoplasm Type Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C67012 SERTOLI CELL TUMOR, ARRHENOBLA A benign neoplasm of the testis or ovary, originating Benign Sertoli Cell Tumor BENIGN STOMA, from Sertoli cells. BENIGN; BENIGN ANDROBLAST OMA

C67006 SERTOLI CELL TUMOR, ARRHENOBLA A malignant neoplasm of the testis or ovary, Malignant Sertoli Cell Tumor MALIGNANT STOMA, originating from Sertoli cells. MALIGNANT; MALIGNANT ANDROBLAST OMA

C98794 SERTOLI CELL TUMOR, An ovarian neoplasm comprising Sertoli cells in which Undetermined Sertoli Cell Tumor UNDETERMINED the malignancy status has not been established.

C6569 STROMAL NEPHROMA, CMN; A congenital malignant neoplasm of the kidney Congenital Mesoblastic Nephroma MALIGNANT MESOBLASTIC characterized by the presence of fibroblastic cells. NEPHROMA

C8973 STROMAL SARCOMA, ESS A malignant, mesenchymal tumor of the uterine Endometrial Stromal Sarcoma ENDOMETRIAL, stroma. MALIGNANT

C6926 STROMAL SARCOMA, STROMAL A malignant neoplasm characterized by the presence of Stromal Sarcoma MALIGNANT TUMOR, atypical mesenchymal-stromal cells. MALIGNANT

C66772 STROMAL TUMOR, A benign neoplasm composed of mesenchymal Benign Stromal Tumor BENIGN stromal cells.

C67561 STROMAL TUMOR, SEX CORD A malignant neoplasm originating from the gonadal sex Malignant Sex Cord-Stromal Tumor GONADAL, MALIGNANT STROMAL cord stroma. TUMOR, MALIGNANT

C3794 STROMAL TUMOR, SEX A neoplasm originating from the gonadal sex cord Sex Cord-Stromal Tumor GONADAL, CORD-STROMA stroma, for which the status of malignancy has not UNDETERMINED L TUMOR, been determined. UNDETERMINE D; SEX CORD-STROMA L NEOPLASM

C3795 SUBEPENDYMOMA, WHO GRADE I A benign neoplasm of the brain localized in the vicinity Subependymoma BENIGN EPENDYMAL of a ventricular wall and is composed of glial tumor TUMOR; WHO cell clusters embedded in an abundant fibrillary matrix GRADE I with frequent microcystic changes. EPENDYMAL NEOPLASM; SUBEPENDYM AL GLIOMA

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 301 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C88025 - NEOPLASM - Neoplasm Type Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C3829 SYNOVIOMA, BENIGN BENIGN A benign neoplasm arising from the synovial Benign Synovial Neoplasm NEOPLASM OF membrane. SYNOVIUM; BENIGN SYNOVIOMA; BENIGN NEOPLASM OF THE SYNOVIUM; BENIGN TUMOR OF THE SYNOVIUM; BENIGN TUMOR OF SYNOVIUM; BENIGN SYNOVIAL TUMOR

C67107 TERATOMA, BENIGN A benign germ-cell neoplasm derived from pluripotent Benign Teratoma cells and consisting of components from one or more of the three germ-cell layers.

C4286 TERATOMA, MALIGNANT IMMATURE A malignant germ-cell neoplasm derived from Immature Teratoma TERATOMA pluripotent cells and consisting of components from one or more of the three germ-cell layers.

C3403 TERATOMA, A germ-cell neoplasm derived from pluripotent cells Teratoma UNDETERMINED and consisting of components from one or more of the three germ-cell layers, for which the malignancy status has not been established.

C5219 THECOMA, BENIGN THECAL CELL A benign sex-cord neoplasm of the ovary, originating Benign Ovarian Thecoma TUMOR, from theca cells. BENIGN; BENIGN THECAL CELL NEOPLASM OF THE OVARY; BENIGN OVARIAN THECAL CELL TUMOR; BENIGN OVARIAN THECAL CELL NEOPLASM; BENIGN THECAL CELL TUMOR OF THE OVARY; BENIGN THECAL CELL TUMOR OF OVARY; BENIGN THECOMA OF THE OVARY; BENIGN THECOMA OF OVARY; BENIGN THECAL CELL NEOPLASM OF OVARY

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 302 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C88025 - NEOPLASM - Neoplasm Type Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C6929 THECOMA, OVARIAN, THECOMA, A malignant sex-cord neoplasm of the ovary, Malignant Ovarian Thecoma MALIGNANT MALIGNANT; originating from theca cells. MALIGNANT THECOMA OF THE OVARY; MALIGNANT THECAL CELL NEOPLASM OF THE OVARY; MALIGNANT THECAL CELL NEOPLASM OF OVARY; MALIGNANT OVARIAN THECAL CELL NEOPLASM; MALIGNANT THECAL CELL TUMOR OF THE OVARY; MALIGNANT THECOMA OF OVARY; MALIGNANT OVARIAN THECAL CELL TUMOR; MALIGNANT THECAL CELL TUMOR OF OVARY

C66746 THYMOMA, BENIGN A benign neoplasm of the thymus, originating from Benign Thymoma epithelial thymus cells.

C7612 THYMOMA, MALIGNANT A malignant neoplasm of the thymus, originating from Malignant Thymoma epithelial thymus cells.

C3411 THYMOMA, A neoplasm of the thymus, originating from epithelial Thymoma UNDETERMINED thymus cells, for which the malignancy status has not been established.

C27132 TRICHOEPITHELIOMA, BROOKE'S A benign hair follicle neoplasm with trichoblastic Trichoblastoma BENIGN TUMOR; differentiation. TRICHOGENIC TRICHOBLAST OMA; TRICHOGENIC ADNEXAL TUMOR; TRICHOEPITHE LIOMA

C3011 YOLK SAC TUMOR, ENDODERMAL A non-seminomatous malignant germ cell tumor Yolk Sac Tumor MALIGNANT SINUS TUMOR; composed of primitive germ cells and which produce YOLK SAC an eosinophilic substance (alpha-fetoprotein). TUMOR SITE UNSPECIFIED; YOLK SAC NEOPLASM; ENDODERMAL SINUS NEOPLASM

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 303 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C78736 - NRIND - Reference Range Indicator Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C78802 ABNORMAL Reported values outside the typical or expected range. Abnormal Reference Range (NCI)

C78800 HIGH Reported values above the typical or expected range. Value Above Reference Range (NCI)

C78801 LOW Reported values below the typical or expected range. Value Below Reference Range (NCI)

C78727 NORMAL Reported values within the typical or expected range. Normal Reference Range (NCI)

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 304 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C66742 - NY - No Yes Response Codelist extensible: No

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C49487 N No The non-affirmative response to a question. (NCI) No

C48660 NA NA Determination of a value is not relevant in the current Not Applicable context. (NCI)

C17998 U U; Unknown Not known, not observed, not recorded, or refused. Unknown (NCI)

C49488 Y Yes The affirmative response to a question. (NCI) Yes

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 305 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C66768 - OUT - Outcome of Event Codelist extensible: No

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C48275 FATAL Grade 5; 5; The termination of life as a result of an adverse event. Death Related to Adverse Event FATAL (NCI)

C49494 NOT RECOVERED/NOT One of the possible results of an adverse event Not Recovered or Not Resolved RESOLVED outcome that indicates that the event has not improved or recuperated. (NCI)

C49498 RECOVERED/RESOLVED One of the possible results of an adverse event Recovered or Resolved outcome that indicates that the event has improved or recuperated. (NCI)

C49495 RECOVERED/RESOLVED One of the possible results of an adverse event Recovered or Resolved with WITH SEQUELAE outcome where the subject recuperated but retained Sequelae pathological conditions resulting from the prior disease or injury. (NCI)

C49496 RECOVERING/RESOLVING One of the possible results of an adverse event Recovering or Resolving outcome that indicates that the event is improving. (NCI)

C17998 UNKNOWN U; Unknown Not known, not observed, not recorded, or refused. Unknown (NCI)

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 306 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C95120 - PHSPRP - Physical Properties Test Name Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C37927 Color Color The appearance of objects (or light sources) described Color in terms of a person's perception of their hue and lightness (or brightness) and saturation. (NCI)

C95110 Consistency Consistency A description about the firmness or make-up of an Consistency entity.

C25333 Depth Depth The extent downward or inward; the perpendicular Depth measurement from the surface downward to determine deepness. (NCI)

C25365 Description Description A written or verbal account, representation, statement, Description or explanation of something. (NCI)

C25285 Diameter Diameter The length of a straight line passing through the center Diameter of a circle or sphere and connecting two points on the circumference. (NCI)

C95109 Hair Cover Hair Cover A description of the quantity or quality of the hair or Hair or Fur Cover fur covering a biological entity. (NCI)

C25334 Length Length The linear extent in space from one end of something Length to the other end, or the extent of something from beginning to end. (NCI)

C25677 Shape Shape The spatial arrangement of something as distinct from Shape its substance. (NCI)

C25757 Ulceration Ulceration The formation or development of an ulcer. (NCI) Ulceration

C25345 Width Width The extent or measurement of something from side to Width side. (NCI)

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 307 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C95121 - PHSPRPCD - Physical Properties Test Code Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C37927 COLOR Color The appearance of objects (or light sources) described Color in terms of a person's perception of their hue and lightness (or brightness) and saturation. (NCI)

C95110 CONSIST Consistency A description about the firmness or make-up of an Consistency entity.

C25333 DEPTH Depth The extent downward or inward; the perpendicular Depth measurement from the surface downward to determine deepness. (NCI)

C25365 DESCR Description A written or verbal account, representation, statement, Description or explanation of something. (NCI)

C25285 DIAMETER Diameter The length of a straight line passing through the center Diameter of a circle or sphere and connecting two points on the circumference. (NCI)

C95109 HAIRCOV Hair Cover A description of the quantity or quality of the hair or Hair or Fur Cover fur covering a biological entity. (NCI)

C25334 LENGTH Length The linear extent in space from one end of something Length to the other end, or the extent of something from beginning to end. (NCI)

C25677 SHAPE Shape The spatial arrangement of something as distinct from Shape its substance. (NCI)

C25757 ULCER Ulceration The formation or development of an ulcer. (NCI) Ulceration

C25345 WIDTH Width The extent or measurement of something from side to Width side. (NCI)

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 308 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C85493 - PKPARM - PK Parameters Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C85763 AUC %Back Extrapolation AUC %Back The percentage of the area under curve extrapolated to Observed Area Under the Curve Obs Extrapolation infinity that was due to back extrapolation to estimate Percent Back Extrapolation Obs concentration at time zero, based on the observed value for concentration at time zero.

C85787 AUC %Back Extrapolation AUC %Back The percentage of the area under the curve (AUC) Predicted Area Under the Curve Pred Extrapolation extrapolated to infinity that was due to back Percent Back Extrapolation Pred extrapolation to estimate concentration at time zero, based on the predicted value for concentration at time zero.

C85764 AUC %Extrapolation Obs AUC The percentage of the area under the curve (AUC) Observed Area Under the Curve %Extrapolation extrapolated to infinity from Tlast to infinity based on Percent Extrapolation Obs the observed value for concentration at TLast.

C85788 AUC %Extrapolation Pred AUC The percentage of the area under the curve (AUC) Predicted Area Under the Curve %Extrapolation extrapolated to infinity from Tlast to infinity based on Percent Extrapolation Pred the predicted value for concentration at TLast.

C85564 AUC All AUC All The area under the curve (AUC) from the time of Area Under the Curve All dosing to the time of the last observation, regardless of whether the last concentration is measurable or not.

C92362 AUC All Norm by BMI AUC All Norm The area under the curve (AUC) from the time of AUC All Normalized by Body Mass by BMI dosing to the time of the last observation divided by Index the body mass index, regardless of whether the last concentration is measurable or not.

C92306 AUC All Norm by Dose AUC All Norm The area under the curve (AUC) from the time of AUC All Normalized by Dose by Dose dosing to the time of the last observation divided by the dose, regardless of whether the last concentration is measurable or not.

C92307 AUC All Norm by SA AUC All Norm The area under the curve (AUC) from the time of AUC All Normalized by Surface by SA dosing to the time of the last observation divided by Area the surface area, regardless of whether the last concentration is measurable or not.

C92308 AUC All Norm by WT AUC All Norm The area under the curve (AUC) from the time of AUC All Normalized by Weight by WT dosing to the time of the last observation divided by the weight, regardless of whether the last concentration is measurable or not.

C85565 AUC Dosing to Last Conc AUC Dosing to The area under the curve (AUC) from the time of Area Under the Curve From Dosing Last Conc dosing to the last measurable concentration. to Last Concentration

C92309 AUC Dosing to Last Conc AUC Dosing to The area under the curve (AUC) from the time of AUC Dosing to Last Concentration Norm by BMI Last Conc Norm dosing to the last measurable concentration divided by Normalized by Body Mass Index by BMI the body mass index.

C92310 AUC Dosing to Last Conc AUC Dosing to The area under the curve (AUC) from the time of AUC Dosing to Last Concentration Norm by Dose Last Conc Norm dosing to the last measurable concentration divided by Normalized by Dose by Dose the dose.

C92311 AUC Dosing to Last Conc AUC Dosing to The area under the curve (AUC) from the time of AUC Dosing to Last Concentration Norm by SA Last Conc Norm dosing to the last measurable concentration divided by Normalized by Surface Area by SA the surface area.

C92305 AUC Dosing to Last Conc AUC Dosing to The area under the curve (AUC) from the time of AUC Dosing to Last Concentration Norm by WT Last Conc Norm dosing to the last measurable concentration divided by Normalized by Weight by WT the weight.

C85761 AUC Infinity Obs AUC Infinity Obs The area under the curve (AUC) extrapolated to Observed Area Under the Curve infinity from dosing time, based on the last observed Infinity concentration.

C92316 AUC Infinity Obs Norm by AUC Infinity Obs The observed area under the curve (AUC) extrapolated AUC Infinity Observed Normalized BMI Norm by BMI to infinity divided by the body mass index. by Body Mass Index

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 309 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C85493 - PKPARM - PK Parameters Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C96695 AUC Infinity Obs Norm by AUC Infinity Obs The observed area under the curve (AUC) extrapolated AUC Infinity Observed Normalized Dose Norm by Dose to infinity divided by the dose. by Dose

C92317 AUC Infinity Obs Norm by SA AUC Infinity Obs The observed area under the curve (AUC) extrapolated AUC Infinity Observed Normalized Norm by SA to infinity divided by the surface area. by Surface Area

C92318 AUC Infinity Obs Norm by AUC Infinity Obs The observed area under the curve (AUC) extrapolated AUC Infinity Observed Normalized WT Norm by WT to infinity divided by the weight. by Weight

C85785 AUC Infinity Pred AUC Infinity The area under the curve (AUC) extrapolated to Predicted Area Under the Curve Pred infinity from dosing time, based on the predicted last Infinity concentration.

C92319 AUC Infinity Pred Norm by AUC Infinity The area under the curve (AUC) extrapolated to AUC Infinity Predicted Normalized BMI Pred Norm by infinity from dosing time, based on the predicted last by Body Mass Index BMI concentration, divided by the body mass index.

C85786 AUC Infinity Pred Norm by AUC Infinity The area under the curve (AUC) extrapolated to Predicted Area Under the Curve Dose Pred Norm by infinity from dosing time, based on the predicted last Infinity by Dose Dose concentration, divided by the dose.

C92320 AUC Infinity Pred Norm by AUC Infinity The area under the curve (AUC) extrapolated to AUC Infinity Predicted Normalized SA Pred Norm by infinity from dosing time, based on the predicted last by Surface Area SA concentration, divided by the surface area.

C92321 AUC Infinity Pred Norm by AUC Infinity The area under the curve (AUC) extrapolated to AUC Infinity Predicted Normalized WT Pred Norm by infinity from dosing time, based on the predicted last by Weight WT concentration, divided by the weight.

C85567 AUC Over Dosing Interval AUC Over The area under the curve (AUC) for the defined Area Under the Curve Over Dosing Dosing Interval interval between doses (TAU). Interval

C92322 AUC Over Dosing Interval AUC Over The area under the curve (AUC) for the defined AUC Over Dosing Interval Norm by BMI Dosing Interval interval between doses (TAU) divided by the body Normalized by Body Mass Index Norm by BMI mass index.

C92323 AUC Over Dosing Interval AUC Over The area under the curve (AUC) for the defined AUC Over Dosing Interval Norm by Dose Dosing Interval interval between doses (TAU) divided by the dose. Normalized by Dose Norm by Dose

C92324 AUC Over Dosing Interval AUC Over The area under the curve (AUC) for the defined AUC Over Dosing Interval Norm by SA Dosing Interval interval between doses (TAU) divided by the surface Normalized by Surface Area Norm by SA area.

C92325 AUC Over Dosing Interval AUC Over The area under the curve (AUC) for the defined AUC Over Dosing Interval Norm by WT Dosing Interval interval between doses (TAU) divided by the weight. Normalized by Weight Norm by WT

C85566 AUC from T1 to T2 AUC from T1 to The area under the curve (AUC) over the interval from Area Under the Curve from T1 to T2 T2 T1 to T2.

C92312 AUC from T1 to T2 Norm by AUC from T1 to The area under the curve (AUC) over the interval from AUC from T1 to T2 Normalized by BMI T2 Norm by BMI T1 to T2 divided by the body mass index. Body Mass Index

C92313 AUC from T1 to T2 Norm by AUC from T1 to The area under the curve (AUC) over the interval from AUC from T1 to T2 Normalized by Dose T2 Norm by T1 to T2 divided by the dose. Dose Dose

C92314 AUC from T1 to T2 Norm by AUC from T1 to The area under the curve (AUC) over the interval from AUC from T1 to T2 Normalized by SA T2 Norm by SA T1 to T2 divided by the surface area. Surface Area

C92315 AUC from T1 to T2 Norm by AUC from T1 to The area under the curve (AUC) over the interval from AUC from T1 to T2 Normalized by WT T2 Norm by WT T1 to T2 divided by the weight. Weight

C85766 AUMC % Extrapolation Obs AUMC % The percentage of the area under the moment curve Observed Area Under the First Extrapolation (AUMC) extrapolated to infinity from Tlast to infinity Moment Curve Percent Obs based on the observed value for concentration at TLast. Extrapolation

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 310 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C85493 - PKPARM - PK Parameters Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C85790 AUMC % Extrapolation Pred AUMC % The percentage of the area under the moment curve Predicted Area Under the First Extrapolation (AUMC) extrapolated to infinity from Tlast to infinity Moment Curve Percent Pred based on the predicted value for concentration at Extrapolation TLast.

C85569 AUMC Dosing to Last Conc AUMC Dosing The area under the moment curve (AUMC) from the Area Under the First Moment Curve to Last Conc time of dosing to the last measurable concentration. From Dosing to Last Concentration

C92326 AUMC Dosing to Last Conc AUMC Dosing The area under the moment curve (AUMC) from the AUMC Dosing to Last Concentration Norm by BMI to Last Conc time of dosing to the last measurable concentration Normalized by Body Mass Index Norm by BMI divided by the body mass index.

C92327 AUMC Dosing to Last Conc AUMC Dosing The area under the moment curve (AUMC) from the AUMC Dosing to Last Concentration Norm by Dose to Last Conc time of dosing to the last measurable concentration Normalized by Dose Norm by Dose divided by the dose.

C92328 AUMC Dosing to Last Conc AUMC Dosing The area under the moment curve (AUMC) from the AUMC Dosing to Last Concentration Norm by SA to Last Conc time of dosing to the last measurable concentration Normalized by Surface Area Norm by SA divided by the surface area.

C92329 AUMC Dosing to Last Conc AUMC Dosing The area under the moment curve (AUMC) from the AUMC Dosing to Last Concentration Norm by WT to Last Conc time of dosing to the last measurable concentration Normalized by Weight Norm by WT divided by the weight.

C85765 AUMC Infinity Obs AUMC Infinity The area under the first moment curve (AUMC) Observed Area Under the First Obs extrapolated to infinity, based on the last observed Moment Curve Infinity concentration.

C92330 AUMC Infinity Obs Norm by AUMC Infinity The area under the first moment curve (AUMC) AUMC Infinity Observed BMI Obs Norm by extrapolated to infinity, based on the last observed Normalized by Body Mass Index BMI concentration divided by the body mass index.

C92331 AUMC Infinity Obs Norm by AUMC Infinity The area under the first moment curve (AUMC) AUMC Infinity Observed Dose Obs Norm by extrapolated to infinity, based on the last observed Normalized by Dose Dose concentration divided by the dose.

C92332 AUMC Infinity Obs Norm by AUMC Infinity The area under the first moment curve (AUMC) AUMC Infinity Observed SA Obs Norm by SA extrapolated to infinity, based on the last observed Normalized by Surface Area concentration divided by the surface area.

C92333 AUMC Infinity Obs Norm by AUMC Infinity The area under the first moment curve (AUMC) AUMC Infinity Observed WT Obs Norm by extrapolated to infinity, based on the last observed Normalized by Weight WT concentration divided by the weight.

C85789 AUMC Infinity Pred AUMC Infinity The area under the first moment curve (AUMC) Predicted Area Under the First Pred extrapolated to infinity, based on the last predicted Moment Curve Infinity concentration.

C92334 AUMC Infinity Pred Norm by AUMC Infinity The area under the first moment curve (AUMC) AUMC Infinity Predicted BMI Pred Norm by extrapolated to infinity, based on the last predicted Normalized by Body Mass Index BMI concentration divided by the body mass index.

C92335 AUMC Infinity Pred Norm by AUMC Infinity The area under the first moment curve (AUMC) AUMC Infinity Predicted Dose Pred Norm by extrapolated to infinity, based on the last predicted Normalized by Dose Dose concentration divided by the dose.

C92336 AUMC Infinity Pred Norm by AUMC Infinity The area under the first moment curve (AUMC) AUMC Infinity Predicted SA Pred Norm by extrapolated to infinity, based on the last predicted Normalized by Surface Area SA concentration divided by the surface area.

C92337 AUMC Infinity Pred Norm by AUMC Infinity The area under the first moment curve (AUMC) AUMC Infinity Predicted WT Pred Norm by extrapolated to infinity, based on the last predicted Normalized by Weight WT concentration divided by the weight.

C85570 AUMC Over Dosing Interval AUMC Over The area under the first moment curve (AUMC) for the Area Under the First Moment Curve Dosing Interval defined interval between doses (TAU). Over Dosing Interval

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 311 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C85493 - PKPARM - PK Parameters Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C92338 AUMC Over Dosing Interval AUMC Over The area under the first moment curve (AUMC) for the AUMC Over Dosing Interval Norm by BMI Dosing Interval defined interval between doses (TAU) divided by the Normalized by Body Mass Index Norm by BMI body mass index.

C92339 AUMC Over Dosing Interval AUMC Over The area under the first moment curve (AUMC) for the AUMC Over Dosing Interval Norm by Dose Dosing Interval defined interval between doses (TAU) divided by the Normalized by Dose Norm by Dose dose.

C92340 AUMC Over Dosing Interval AUMC Over The area under the first moment curve (AUMC) for the AUMC Over Dosing Interval Norm by SA Dosing Interval defined interval between doses (TAU) divided by the Normalized by Surface Area Norm by SA surface area.

C92341 AUMC Over Dosing Interval AUMC Over The area under the first moment curve (AUMC) for the AUMC Over Dosing Interval Norm by WT Dosing Interval defined interval between doses (TAU) divided by the Normalized by Weight Norm by WT weight.

C85768 AURC % Extrapolation Obs AURC % The percentage of the area under the urine excretion Observed Area Under the Urinary Extrapolation rate curve (AURC) extrapolated to infinity observed Excretion Rate Curve Percent Obs from Tlast to infinity. Extrapolation

C85792 AURC % Extrapolation Pred AURC % The percentage of the area under the urine excretion Predicted Area Under the Urinary Extrapolation rate curve (AURC) extrapolated to infinity predicted Excretion Rate Curve Percent Pred from Tlast to infinity. Extrapolation

C85841 AURC All AURC All The area under the urinary excretion rate curve Area Under Urinary Excretion Rate (AURC) from time zero to the last measurable rate. Curve All

C92342 AURC All Norm by BMI AURC All Norm The area under the urinary excretion rate curve AURC All Normalized by Body Mass by BMI (AURC) from time zero to the last measurable rate Index divided by the body mass index.

C92343 AURC All Norm by Dose AURC All Norm The area under the urinary excretion rate curve AURC All Normalized by Dose by Dose (AURC) from time zero to the last measurable rate divided by the dose.

C92344 AURC All Norm by SA AURC All Norm The area under the urinary excretion rate curve AURC All Normalized by Surface by SA (AURC) from time zero to the last measurable rate Area divided by the surface area.

C92345 AURC All Norm by WT AURC All Norm The area under the urinary excretion rate curve AURC All Normalized by Weight by WT (AURC) from time zero to the last measurable rate divided by the weight.

C85571 AURC Dosing to Last Conc AURC Dosing to The area under the urinary excretion rate curve Area Under the Urinary Excretion Last Conc (AURC) from time zero to the last measurable rate. Rate Curve From Dosing to Last Concentration

C92346 AURC Dosing to Last Conc AURC Dosing to The area under the urinary excretion rate curve AURC Dosing to Last Concentration Norm by BMI Last Conc Norm (AURC) from time zero to the last measurable rate, Normalized by Body Mass Index by BMI divided by the body mass index.

C92347 AURC Dosing to Last Conc AURC Dosing to The area under the urinary excretion rate curve AURC Dosing to Last Concentration Norm by Dose Last Conc Norm (AURC) from time zero to the last measurable rate, Normalized by Dose by Dose divided by the dose.

C92348 AURC Dosing to Last Conc AURC Dosing to The area under the urinary excretion rate curve AURC Dosing to Last Concentration Norm by SA Last Conc Norm (AURC) from time zero to the last measurable rate, Normalized by Surface Area by SA divided by the surface area.

C92349 AURC Dosing to Last Conc AURC Dosing to The area under the urinary excretion rate curve AURC Dosing to Last Concentration Norm by WT Last Conc Norm (AURC) from time zero to the last measurable rate, Normalized by Weight by WT divided by the weight.

C85767 AURC Infinity Obs AURC Infinity The area under the urinary excretion rate curve Observed Area Under the Urinary Obs (AURC) extrapolated to infinity, based on the last Excretion Rate Curve infinity observed excretion rate.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 312 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C85493 - PKPARM - PK Parameters Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C92354 AURC Infinity Obs Norm by AURC Infinity The area under the urinary excretion rate curve AURC Infinity Observed Normalized BMI Obs Norm by (AURC) extrapolated to infinity, based on the last by Body Mass Index BMI observed excretion rate, divided by the body mass index.

C92355 AURC Infinity Obs Norm by AURC Infinity The area under the urinary excretion rate curve AURC Infinity Observed Normalized Dose Obs Norm by (AURC) extrapolated to infinity, based on the last by Dose Dose observed excretion rate, divided by the dose.

C92356 AURC Infinity Obs Norm by AURC Infinity The area under the urinary excretion rate curve AURC Infinity Observed Normalized SA Obs Norm by SA (AURC) extrapolated to infinity, based on the last by Surface Area observed excretion rate, divided by the surface area.

C92357 AURC Infinity Obs Norm by AURC Infinity The area under the urinary excretion rate curve AURC Infinity Observed Normalized WT Obs Norm by (AURC) extrapolated to infinity, based on the last by Weight WT observed excretion rate, divided by the weight.

C85791 AURC Infinity Pred AURC Infinity The area under the urinary excretion rate curve Predicted Area Under the Urinary Pred (AURC) extrapolated to infinity, based on the last Excretion Rate Curve Infinity predicted excretion rate.

C92358 AURC Infinity Pred Norm by AURC Infinity The area under the urinary excretion rate curve AURC Infinity Predicted Normalized BMI Pred Norm by (AURC) extrapolated to infinity, based on the last by Body Mass Index BMI predicted excretion rate, divided by the body mass index.

C92359 AURC Infinity Pred Norm by AURC Infinity The area under the urinary excretion rate curve AURC Infinity Predicted Normalized Dose Pred Norm by (AURC) extrapolated to infinity, based on the last by Dose Dose predicted excretion rate, divided by the dose.

C92360 AURC Infinity Pred Norm by AURC Infinity The area under the urinary excretion rate curve AURC Infinity Predicted Normalized SA Pred Norm by (AURC) extrapolated to infinity, based on the last by Surface Area SA predicted excretion rate, divided by the surface area.

C92361 AURC Infinity Pred Norm by AURC Infinity The area under the urinary excretion rate curve AURC Infinity Predicted Normalized WT Pred Norm by (AURC) extrapolated to infinity, based on the last by Weight WT predicted excretion rate, divided by the weight.

C85572 AURC from T1 to T2 AURC from T1 The area under the urinary excretion rate curve Area Under the Urinary Excretion to T2 (AURC) over the interval from T1 to T2. Rate Curve from T1 to T2

C92350 AURC from T1 to T2 Norm by AURC from T1 The area under the urinary excretion rate curve AURC from T1 to T2 Normalized by BMI to T2 Norm by (AURC) over the interval from T1 to T2 divided by the Body Mass Index BMI body mass index.

C92351 AURC from T1 to T2 Norm by AURC from T1 The area under the urinary excretion rate curve AURC from T1 to T2 Normalized by Dose to T2 Norm by (AURC) over the interval from T1 to T2 divided by the Dose Dose dose.

C92352 AURC from T1 to T2 Norm by AURC from T1 The area under the urinary excretion rate curve AURC from T1 to T2 Normalized by SA to T2 Norm by (AURC) over the interval from T1 to T2 divided by the Surface Area SA surface area.

C92353 AURC from T1 to T2 Norm by AURC from T1 The area under the urinary excretion rate curve AURC from T1 to T2 Normalized by WT to T2 Norm by (AURC) over the interval from T1 to T2 divided by the Weight WT weight.

C85832 Amount Recovered Amount The cumulative amount recovered from the specimen Amount Recovered Recovered type specified in PPSPEC, from dosing to end of the current collection interval.

C92363 Amount Recovered Norm by Amount The cumulative amount recovered from the specimen Amount Recovered Normalized by BMI Recovered Norm type specified in PPSPEC, from dosing to end of the Body Mass Index by BMI current collection interval divided by the body mass index.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 313 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C85493 - PKPARM - PK Parameters Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C92364 Amount Recovered Norm by Amount The cumulative amount recovered from the specimen Amount Recovered Normalized by Dose Recovered Norm type specified in PPSPEC, from dosing to end of the Dose by Dose current collection interval divided by the dose.

C92365 Amount Recovered Norm by Amount The cumulative amount recovered from the specimen Amount Recovered Normalized by SA Recovered Norm type specified in PPSPEC, from dosing to end of the Surface Area by SA current collection interval divided by the surface area.

C92366 Amount Recovered Norm by Amount The cumulative amount recovered from the specimen Amount Recovered Normalized by WT Recovered Norm type specified in PPSPEC, from dosing to end of the Weight by WT current collection interval divided by the weight.

C85575 Average Conc Average Conc; AUCTAU divided by TAU. Average Concentration Average Concentration

C92367 Average Conc Norm by BMI Average Conc AUCTAU divided by TAU and then divided by the body Average Concentration Normalized Norm by BMI mass index. by Body Mass Index

C92368 Average Conc Norm by Dose Average Conc AUCTAU divided by TAU and then divided by the dose. Average Concentration Normalized Norm by Dose by Dose

C92369 Average Conc Norm by SA Average Conc AUCTAU divided by TAU and then divided by the Average Concentration Normalized Norm by SA surface area. by Surface Area

C92370 Average Conc Norm by WT Average Conc AUCTAU divided by TAU and then divided by the Average Concentration Normalized Norm by WT weight. by Weight

C92378 Conc After the Nth Dose Conc After the The concentration at the Nth dose. Concentration After the Nth Dose Nth Dose

C92379 Conc After the Nth Dose by Conc After the The concentration at the Nth dose divided by the body Concentration After the Nth Dose by BMI Nth Dose by mass index. Body Mass Index BMI

C92380 Conc After the Nth Dose by Conc After the The concentration at the Nth dose divided by the dose. Concentration After the Nth Dose by Dose Nth Dose by Dose Dose

C92381 Conc After the Nth Dose by Conc After the The concentration at the Nth dose divided by the Concentration After the Nth Dose by SA Nth Dose by SA surface area. Surface Area

C92382 Conc After the Nth Dose by Conc After the The concentration at the Nth dose divided by the Concentration After the Nth Dose by WT Nth Dose by WT weight. Weight

C85821 Correlation Between TimeX Correlation The correlation between time (X) and log Time and Log Concentration and Log ConcY Between TimeX concentration (Y) for the points used in the estimation Correlation and Log ConcY of lambda z.

C85581 Fluctuation% Fluctuation% The difference between Cmin and Cmax standardized Concentration Variability Between to Cavg, between dose time and Tau. Dose Time and Tau

C85818 Half-Life Lambda z Half-Life Terminal half-life. Terminal Half Life Lambda z

C85644 Initial Conc Initial Conc Initial concentration. Given only for bolus IV models. Initial Concentration

C92383 Initial Conc Norm by BMI Initial Conc Initial concentration divided by the body mass index. Initial Concentration Normalized by Norm by BMI Given only for bolus IV models. Body Mass Index

C92384 Initial Conc Norm by Dose Initial Conc Initial concentration divided by the dose. Given only Initial Concentration Normalized by Norm by Dose for bolus IV models. Dose

C92385 Initial Conc Norm by SA Initial Conc Initial concentration divided by the surface area. Given Initial Concentration Normalized by Norm by SA only for bolus IV models. Surface Area

C92386 Initial Conc Norm by WT Initial Conc Initial concentration divided by the weight. Given only Initial Concentration Normalized by Norm by WT for bolus IV models. Weight

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 314 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C85493 - PKPARM - PK Parameters Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C85652 Lambda z Lambda z The first order rate constant associated with the Lambda Z terminal (log-linear) portion of the curve.

C85653 Lambda z Lower Limit Lambda z Lower The lower limit on time for values to be included in the Lambda Z Time Lower Limit Limit calculation of Lambda z.

C85654 Lambda z Upper Limit Lambda z Upper The upper limit on time for values to be included in the Lambda Z Time Upper Limit Limit calculation of Lambda z.

C85655 Last Conc Last Conc The concentration corresponding to Tlast. Last Concentration

C92387 Last Conc Norm by BMI Last Conc Norm The concentration corresponding to Tlast divided by Last Concentration Normalized by by BMI the body mass index. Body Mass Index

C92388 Last Conc Norm by Dose Last Conc Norm The concentration corresponding to Tlast divided by Last Concentration Normalized by by Dose the dose. Dose

C92389 Last Conc Norm by SA Last Conc Norm The concentration corresponding to Tlast divided by Last Concentration Normalized by by SA the surface area. Surface Area

C92390 Last Conc Norm by WT Last Conc Norm The concentration corresponding to Tlast divided by Last Concentration Normalized by by WT the weight. Weight

C85656 Last Meas Excretion Rate Last Meas The last measurable (positive) excretion rate. Last Measurable Observed Excretion Excretion Rate Rate

C92391 Last Meas Excretion Rate Last Meas The last measurable (positive) excretion rate divided Last Measurable Excretion Rate Norm by BMI Excretion Rate by the body mass index. Normalized by Body Mass Index Norm by BMI

C92392 Last Meas Excretion Rate Last Meas The last measurable (positive) excretion rate divided Last Measurable Excretion Rate Norm by Dose Excretion Rate by the dose. Normalized by Dose Norm by Dose

C92393 Last Meas Excretion Rate Last Meas The last measurable (positive) excretion rate divided Last Measurable Excretion Rate Norm by SA Excretion Rate by the surface area. Normalized by Surface Area Norm by SA

C92394 Last Meas Excretion Rate Last Meas The last measurable (positive) excretion rate divided Last Measurable Excretion Rate Norm by WT Excretion Rate by the weight. Normalized by Weight Norm by WT

C85769 MRT Infinity Obs MRT Infinity The observed mean residence time (MRT) extrapolated Observed Mean Residence Time Obs to infinity. Infinity

C85793 MRT Infinity Pred MRT Infinity The predicted mean residence time (MRT) Predicted Mean Residence Time Pred extrapolated to infinity. Infinity

C85700 MRT Last MRT Last Mean residence time (MRT) from the time of dosing Mean Residence Time Last to the time of the last measurable concentration.

C70918 Max Conc Max Conc The maximum concentration occurring at Tmax. Cmax

C92371 Max Conc Norm by BMI Max Conc Norm The maximum concentration occurring at Tmax, Maximum Concentration Normalized by BMI divided by the body mass index. by Body Mass Index

C85698 Max Conc Norm by Dose Max Conc Norm The maximum concentration occurring at Tmax, Maximum Concentration Dose by Dose divided by the dose. Normalized

C92372 Max Conc Norm by SA Max Conc Norm The maximum concentration occurring at Tmax, Maximum Concentration Normalized by SA divided by the surface area. by Surface Area

C92373 Max Conc Norm by WT Max Conc Norm The maximum concentration occurring at Tmax, Maximum Concentration Normalized by WT divided by the weight. by Weight

C85699 Max Obs Excretion Rate Max Obs The maximum observed excretion rate. Maximum Observed Excretion Rate Excretion Rate

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 315 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C85493 - PKPARM - PK Parameters Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C92395 Max Obs Excretion Rate Max Obs The maximum observed excretion rate divided by the Maximum Observed Excretion Rate Norm by BMI Excretion Rate body mass index. Normalized by Body Mass Index Norm by BMI

C92396 Max Obs Excretion Rate Max Obs The maximum observed excretion rate divided by the Maximum Observed Excretion Rate Norm by Dose Excretion Rate dose. Normalized by Dose Norm by Dose

C92397 Max Obs Excretion Rate Max Obs The maximum observed excretion rate divided by the Maximum Observed Excretion Rate Norm by SA Excretion Rate surface area. Normalized by Surface Area Norm by SA

C92398 Max Obs Excretion Rate Max Obs The maximum observed excretion rate divided by the Maximum Observed Excretion Rate Norm by WT Excretion Rate weight. Normalized by Weight Norm by WT

C85580 Midpoint of Entire Collection Midpoint of The midpoint of collection interval, which is Collection Interval Midpoint Interval Entire Collection associated with last Measurable rate. Interval

C85579 Min Conc Min Conc The minimum concentration between dose time and Cmin dose time plus Tau (at Tmin).

C92374 Min Conc Norm by BMI Min Conc Norm The minimum concentration between dose time and Minimum Concentration Normalized by BMI dose time plus Tau (at Tmin) divided by the body mass by Body Mass Index index.

C92375 Min Conc Norm by Dose Min Conc Norm The minimum concentration between dose time and Minimum Concentration Normalized by Dose dose time plus Tau (at Tmin) divided by the dose. by Dose

C92376 Min Conc Norm by SA Min Conc Norm The minimum concentration between dose time and Minimum Concentration Normalized by SA dose time plus Tau (at Tmin) divided by the surface by Surface Area area.

C92377 Min Conc Norm by WT Min Conc Norm The minimum concentration between dose time and Minimum Concentration Normalized by WT dose time plus Tau (at Tmin) divided by the weight. by Weight

C85816 Number of Points for Lambda Number of The number of time points used in computing Lambda Sum of Lambda Z Timepoints z Points for z. Lambda z

C85777 Percent Recovered Percent The percentage of the dose that is recovered from the Percent Recovered Recovered specimen type specified in PPSPEC, from dosing to end of the current collection interval.

C92413 Percent Recovered Norm by Percent The percentage of the dose that is recovered from the Percent Recovered Normalized by BMI Recovered Norm specimen type specified in PPSPEC, from dosing to Body Mass Index by BMI end of the current collection interval divided by the body mass index.

C92414 Percent Recovered Norm by Percent The percentage of the dose that is recovered from the Percent Recovered Normalized by Dose Recovered Norm specimen type specified in PPSPEC, from dosing to Dose by Dose end of the current collection interval divided by the dose.

C92415 Percent Recovered Norm by Percent The percentage of the dose that is recovered from the Percent Recovered Normalized by SA Recovered Norm specimen type specified in PPSPEC, from dosing to Surface Area by SA end of the current collection interval divided by the surface area.

C92416 Percent Recovered Norm by Percent The percentage of the dose that is recovered from the Percent Recovered Normalized by WT Recovered Norm specimen type specified in PPSPEC, from dosing to Weight by WT end of the current collection interval divided by the weight.

C85542 R Squared R Squared The goodness of fit statistic for the terminal R Squared elimination phase.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 316 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C85493 - PKPARM - PK Parameters Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C85553 R Squared Adjusted R Squared The goodness of fit statistic for the terminal Adjusted R Squared Adjusted elimination phase, adjusted for the number of time points used in the estimation of Lambda z.

C85817 Sum of Urine Vol Used for Sum of Urine The sum of urine volumes that are used for PK Sum Urine Volume PK Parameters Vol Used for PK parameters. Parameters

C85824 Time Until First Nonzero Time Until First The time prior to the first measurable (non-zero) Time until First Nonzero Conc Nonzero Conc concentration. Concentration

C70919 Time of CMAX Observation Time of CMAX The time of maximum observed concentration sampled Tmax Observation during a dosing interval.

C85825 Time of CMIN Observation Time of CMIN The time of minimum concentration sampled during a Tmin Observation dosing interval.

C85822 Time of Last Nonzero Conc Time of Last The time of the last measurable (positive) Time of Last Nonzero Concentration Nonzero Conc concentration.

C85823 Time of Max Excretion Rate Time of Max The midpoint of collection interval associated with the Time of Maximum Observed Excretion Rate maximum observed excretion rate. Excretion Rate

C85773 Total CL Obs Total CL Obs The observed total body clearance for intravascular Observed Total Body Clearance Rate administration.

C92403 Total CL Obs Norm by BMI Total CL Obs The observed total body clearance for intravascular Total Clearance Observed Norm by BMI administration divided by the body mass index. Normalized by Body Mass Index

C92404 Total CL Obs Norm by Dose Total CL Obs The observed total body clearance for intravascular Total Clearance Observed Norm by Dose administration divided by the dose. Normalized by Dose

C92405 Total CL Obs Norm by SA Total CL Obs The observed total body clearance for intravascular Total Clearance Observed Norm by SA administration divided by the surface area. Normalized by Surface Area

C92406 Total CL Obs Norm by WT Total CL Obs The observed total body clearance for intravascular Total Clearance Observed Norm by WT administration divided by the weight. Normalized by Weight

C85772 Total CL Obs by Fract Dose Total CL Obs by The observed total body clearance for extravascular Observed Total Body Clearance by Fract Dose administration based on the fraction of dose absorbed. Fraction of Dose Absorbed

C92399 Total CL Obs by Fract Dose Total CL Obs by The observed total body clearance for extravascular Total Clearance Observed by Norm by BMI Fract Dose Norm administration based on the fraction of dose absorbed Fraction Dose Normalized by Body by BMI and divided by the body mass index. Mass Index

C92400 Total CL Obs by Fract Dose Total CL Obs by The observed total body clearance for extravascular Total Clearance Observed by Norm by Dose Fract Dose Norm administration based on the fraction of dose absorbed Fraction Dose Normalized by Dose by Dose and divided by the dose.

C92401 Total CL Obs by Fract Dose Total CL Obs by The observed total body clearance for extravascular Total Clearance Observed by Norm by SA Fract Dose Norm administration based on the fraction of dose absorbed Fraction Dose Normalized by by SA and divided by the surface area. Surface Area

C92402 Total CL Obs by Fract Dose Total CL Obs by The observed total body clearance for extravascular Total Clearance Observed by Norm by WT Fract Dose Norm administration based on the fraction of dose absorbed Fraction Dose Normalized by by WT and divided by the weight. Weight

C85797 Total CL Pred Total CL Pred The predicted total body clearance for intravascular Predicted Total Body Clearance Rate administration.

C92421 Total CL Pred Norm by BMI Total CL Pred The predicted total body clearance for intravascular Total Clearance Predicted Norm by BMI administration divided by the body mass index. Normalized by Body Mass Index

C92422 Total CL Pred Norm by Dose Total CL Pred The predicted total body clearance for intravascular Total Clearance Predicted Norm by Dose administration divided by the dose. Normalized by Dose

C92423 Total CL Pred Norm by SA Total CL Pred The predicted total body clearance for intravascular Total Clearance Predicted Norm by SA administration divided by the surface area. Normalized by Surface Area

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 317 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C85493 - PKPARM - PK Parameters Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C92424 Total CL Pred Norm by WT Total CL Pred The predicted total body clearance for intravascular Total Clearance Predicted Norm by WT administration divided by the weight. Normalized by Weight

C85796 Total CL Pred by Fract Dose Total CL Pred by The predicted total body clearance for extravascular Predicted Total Body Clearance by Fract Dose administration based on the fraction of dose absorbed. Fraction of Dose Absorbed

C92417 Total CL Pred by Fract Dose Total CL Pred by The predicted total body clearance for extravascular Total Clearance Predicted by Norm by BMI Fract Dose Norm administration based on the fraction of dose absorbed Fraction Dose Normalized by Body by BMI and divided by the body mass index. Mass Index

C92418 Total CL Pred by Fract Dose Total CL Pred by The predicted total body clearance for extravascular Total Clearance Predicted by Norm by Dose Fract Dose Norm administration based on the fraction of dose absorbed Fraction Dose Normalized by Dose by Dose and divided by the dose.

C92419 Total CL Pred by Fract Dose Total CL Pred by The predicted total body clearance for extravascular Total Clearance Predicted by Norm by SA Fract Dose Norm administration based on the fraction of dose absorbed Fraction Dose Normalized by by SA and divided by the surface area. Surface Area

C92420 Total CL Pred by Fract Dose Total CL Pred by The predicted total body clearance for extravascular Total Clearance Predicted by Norm by WT Fract Dose Norm administration based on the fraction of dose absorbed Fraction Dose Normalized by by WT and divided by the weight. Weight

C85775 Vol Dist of Fract Dose Obs Vol Dist of Fract The observed volume of distribution of the absorbed Observed Volume of Distribution of Dose Obs fraction associated with the terminal slope following Absorbed Fraction extravascular administration, where F equals the fraction of dose absorbed.

C92410 Vol Dist of Fract Dose Obs Vol Dist of Fract The observed volume of distribution of the absorbed Volume of Distribution of Fraction Norm by BMI Dose Obs Norm fraction associated with the terminal slope following Dose Observed Normalized by Body by BMI extravascular administration, where F equals the Mass Index fraction of dose absorbed, divided by the body mass index.

C92411 Vol Dist of Fract Dose Obs Vol Dist of Fract The observed volume of distribution of the absorbed Volume of Distribution of Fraction Norm by SA Dose Obs Norm fraction associated with the terminal slope following Dose Observed Normalized by by SA extravascular administration, where F equals the Surface Area fraction of dose absorbed, divided by the surface area.

C92412 Vol Dist of Fract Dose Obs Vol Dist of Fract The observed volume of distribution of the absorbed Volume of Distribution of Fraction Norm by WT Dose Obs Norm fraction associated with the terminal slope following Dose Observed Normalized by by WT extravascular administration, where F equals the Weight fraction of dose absorbed, divided by the weight.

C85799 Vol Dist of Fract Dose Pred Vol Dist of Fract The predicted volume of distribution of the absorbed Predicted Volume of Distribution of Dose Pred fraction associated with the terminal slope following Absorbed Fraction extravascular administration, where F equals the fraction of dose absorbed.

C92428 Vol Dist of Fract Dose Pred Vol Dist of Fract The predicted volume of distribution of the absorbed Volume of Distribution of Fraction Norm by BMI Dose Pred Norm fraction associated with the terminal slope following Dose Predicted Normalized by Body by BMI extravascular administration, where F equals the Mass Index fraction of dose absorbed, divided by the body mass index.

C92429 Vol Dist of Fract Dose Pred Vol Dist of Fract The predicted volume of distribution of the absorbed Volume of Distribution of Fraction Norm by SA Dose Pred Norm fraction associated with the terminal slope following Dose Predicted Normalized by by SA extravascular administration, where F equals the Surface Area fraction of dose absorbed, divided by the surface area.

C92430 Vol Dist of Fract Dose Pred Vol Dist of Fract The predicted volume of distribution of the absorbed Volume of Distribution of Fraction Norm by WT Dose Pred Norm fraction associated with the terminal slope following Dose Predicted Normalized by by WT extravascular administration, where F equals the Weight fraction of dose absorbed, divided by the weight.

C85774 Vz Obs Vz Obs The observed volume of distribution associated with Observed Volume of Distribution the terminal slope following intravascular administration.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 318 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C85493 - PKPARM - PK Parameters Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C92407 Vz Obs Norm by BMI Vz Obs Norm by The observed volume of distribution associated with Volume of Distribution Observed BMI the terminal slope following intravascular Normalized by Body Mass Index administration divided by the body mass index.

C92408 Vz Obs Norm by SA Vz Obs Norm by The observed volume of distribution associated with Volume of Distribution Observed SA the terminal slope following intravascular Normalized by Surface Area administration divided by the surface area.

C92409 Vz Obs Norm by WT Vz Obs Norm by The observed volume of distribution associated with Volume of Distribution Observed WT the terminal slope following intravascular Normalized by Weight administration divided by the weight.

C85798 Vz Pred Vz Pred The predicted volume of distribution associated with Predicted Volume of Distribution the terminal slope following intravascular administration.

C92425 Vz Pred Norm by BMI Vz Pred Norm by The predicted volume of distribution associated with Volume of Distribution Predicted BMI the terminal slope following intravascular Normalized by Body Mass Index administration divided by the body mass index.

C92426 Vz Pred Norm by SA Vz Pred Norm by The predicted volume of distribution associated with Volume of Distribution Predicted SA the terminal slope following intravascular Normalized by Surface Area administration divided by the surface area.

C92427 Vz Pred Norm by WT Vz Pred Norm by The predicted volume of distribution associated with Volume of Distribution Predicted WT the terminal slope following intravascular Normalized by Weight administration divided by the weight.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 319 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C85839 - PKPARMCD - PK Parameters Code Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C85564 AUCALL AUC All The area under the curve (AUC) from the time of Area Under the Curve All dosing to the time of the last observation, regardless of whether the last concentration is measurable or not.

C92362 AUCALLB AUC All Norm The area under the curve (AUC) from the time of AUC All Normalized by Body Mass by BMI dosing to the time of the last observation divided by Index the body mass index, regardless of whether the last concentration is measurable or not.

C92306 AUCALLD AUC All Norm The area under the curve (AUC) from the time of AUC All Normalized by Dose by Dose dosing to the time of the last observation divided by the dose, regardless of whether the last concentration is measurable or not.

C92307 AUCALLS AUC All Norm The area under the curve (AUC) from the time of AUC All Normalized by Surface by SA dosing to the time of the last observation divided by Area the surface area, regardless of whether the last concentration is measurable or not.

C92308 AUCALLW AUC All Norm The area under the curve (AUC) from the time of AUC All Normalized by Weight by WT dosing to the time of the last observation divided by the weight, regardless of whether the last concentration is measurable or not.

C85761 AUCIFO AUC Infinity Obs The area under the curve (AUC) extrapolated to Observed Area Under the Curve infinity from dosing time, based on the last observed Infinity concentration.

C92316 AUCIFOB AUC Infinity Obs The observed area under the curve (AUC) extrapolated AUC Infinity Observed Normalized Norm by BMI to infinity divided by the body mass index. by Body Mass Index

C96695 AUCIFOD AUC Infinity Obs The observed area under the curve (AUC) extrapolated AUC Infinity Observed Normalized Norm by Dose to infinity divided by the dose. by Dose

C92317 AUCIFOS AUC Infinity Obs The observed area under the curve (AUC) extrapolated AUC Infinity Observed Normalized Norm by SA to infinity divided by the surface area. by Surface Area

C92318 AUCIFOW AUC Infinity Obs The observed area under the curve (AUC) extrapolated AUC Infinity Observed Normalized Norm by WT to infinity divided by the weight. by Weight

C85785 AUCIFP AUC Infinity The area under the curve (AUC) extrapolated to Predicted Area Under the Curve Pred infinity from dosing time, based on the predicted last Infinity concentration.

C92319 AUCIFPB AUC Infinity The area under the curve (AUC) extrapolated to AUC Infinity Predicted Normalized Pred Norm by infinity from dosing time, based on the predicted last by Body Mass Index BMI concentration, divided by the body mass index.

C85786 AUCIFPD AUC Infinity The area under the curve (AUC) extrapolated to Predicted Area Under the Curve Pred Norm by infinity from dosing time, based on the predicted last Infinity by Dose Dose concentration, divided by the dose.

C92320 AUCIFPS AUC Infinity The area under the curve (AUC) extrapolated to AUC Infinity Predicted Normalized Pred Norm by infinity from dosing time, based on the predicted last by Surface Area SA concentration, divided by the surface area.

C92321 AUCIFPW AUC Infinity The area under the curve (AUC) extrapolated to AUC Infinity Predicted Normalized Pred Norm by infinity from dosing time, based on the predicted last by Weight WT concentration, divided by the weight.

C85566 AUCINT AUC from T1 to The area under the curve (AUC) over the interval from Area Under the Curve from T1 to T2 T2 T1 to T2.

C92312 AUCINTB AUC from T1 to The area under the curve (AUC) over the interval from AUC from T1 to T2 Normalized by T2 Norm by BMI T1 to T2 divided by the body mass index. Body Mass Index

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 320 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C85839 - PKPARMCD - PK Parameters Code Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C92313 AUCINTD AUC from T1 to The area under the curve (AUC) over the interval from AUC from T1 to T2 Normalized by T2 Norm by T1 to T2 divided by the dose. Dose Dose

C92314 AUCINTS AUC from T1 to The area under the curve (AUC) over the interval from AUC from T1 to T2 Normalized by T2 Norm by SA T1 to T2 divided by the surface area. Surface Area

C92315 AUCINTW AUC from T1 to The area under the curve (AUC) over the interval from AUC from T1 to T2 Normalized by T2 Norm by WT T1 to T2 divided by the weight. Weight

C85565 AUCLST AUC Dosing to The area under the curve (AUC) from the time of Area Under the Curve From Dosing Last Conc dosing to the last measurable concentration. to Last Concentration

C92309 AUCLSTB AUC Dosing to The area under the curve (AUC) from the time of AUC Dosing to Last Concentration Last Conc Norm dosing to the last measurable concentration divided by Normalized by Body Mass Index by BMI the body mass index.

C92310 AUCLSTD AUC Dosing to The area under the curve (AUC) from the time of AUC Dosing to Last Concentration Last Conc Norm dosing to the last measurable concentration divided by Normalized by Dose by Dose the dose.

C92311 AUCLSTS AUC Dosing to The area under the curve (AUC) from the time of AUC Dosing to Last Concentration Last Conc Norm dosing to the last measurable concentration divided by Normalized by Surface Area by SA the surface area.

C92305 AUCLSTW AUC Dosing to The area under the curve (AUC) from the time of AUC Dosing to Last Concentration Last Conc Norm dosing to the last measurable concentration divided by Normalized by Weight by WT the weight.

C85763 AUCPBEO AUC %Back The percentage of the area under curve extrapolated to Observed Area Under the Curve Extrapolation infinity that was due to back extrapolation to estimate Percent Back Extrapolation Obs concentration at time zero, based on the observed value for concentration at time zero.

C85787 AUCPBEP AUC %Back The percentage of the area under the curve (AUC) Predicted Area Under the Curve Extrapolation extrapolated to infinity that was due to back Percent Back Extrapolation Pred extrapolation to estimate concentration at time zero, based on the predicted value for concentration at time zero.

C85764 AUCPEO AUC The percentage of the area under the curve (AUC) Observed Area Under the Curve %Extrapolation extrapolated to infinity from Tlast to infinity based on Percent Extrapolation Obs the observed value for concentration at TLast.

C85788 AUCPEP AUC The percentage of the area under the curve (AUC) Predicted Area Under the Curve %Extrapolation extrapolated to infinity from Tlast to infinity based on Percent Extrapolation Pred the predicted value for concentration at TLast.

C85567 AUCTAU AUC Over The area under the curve (AUC) for the defined Area Under the Curve Over Dosing Dosing Interval interval between doses (TAU). Interval

C92322 AUCTAUB AUC Over The area under the curve (AUC) for the defined AUC Over Dosing Interval Dosing Interval interval between doses (TAU) divided by the body Normalized by Body Mass Index Norm by BMI mass index.

C92323 AUCTAUD AUC Over The area under the curve (AUC) for the defined AUC Over Dosing Interval Dosing Interval interval between doses (TAU) divided by the dose. Normalized by Dose Norm by Dose

C92324 AUCTAUS AUC Over The area under the curve (AUC) for the defined AUC Over Dosing Interval Dosing Interval interval between doses (TAU) divided by the surface Normalized by Surface Area Norm by SA area.

C92325 AUCTAUW AUC Over The area under the curve (AUC) for the defined AUC Over Dosing Interval Dosing Interval interval between doses (TAU) divided by the weight. Normalized by Weight Norm by WT

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 321 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C85839 - PKPARMCD - PK Parameters Code Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C85765 AUMCIFO AUMC Infinity The area under the first moment curve (AUMC) Observed Area Under the First Obs extrapolated to infinity, based on the last observed Moment Curve Infinity concentration.

C92330 AUMCIFOB AUMC Infinity The area under the first moment curve (AUMC) AUMC Infinity Observed Obs Norm by extrapolated to infinity, based on the last observed Normalized by Body Mass Index BMI concentration divided by the body mass index.

C92331 AUMCIFOD AUMC Infinity The area under the first moment curve (AUMC) AUMC Infinity Observed Obs Norm by extrapolated to infinity, based on the last observed Normalized by Dose Dose concentration divided by the dose.

C92332 AUMCIFOS AUMC Infinity The area under the first moment curve (AUMC) AUMC Infinity Observed Obs Norm by SA extrapolated to infinity, based on the last observed Normalized by Surface Area concentration divided by the surface area.

C92333 AUMCIFOW AUMC Infinity The area under the first moment curve (AUMC) AUMC Infinity Observed Obs Norm by extrapolated to infinity, based on the last observed Normalized by Weight WT concentration divided by the weight.

C85789 AUMCIFP AUMC Infinity The area under the first moment curve (AUMC) Predicted Area Under the First Pred extrapolated to infinity, based on the last predicted Moment Curve Infinity concentration.

C92334 AUMCIFPB AUMC Infinity The area under the first moment curve (AUMC) AUMC Infinity Predicted Pred Norm by extrapolated to infinity, based on the last predicted Normalized by Body Mass Index BMI concentration divided by the body mass index.

C92335 AUMCIFPD AUMC Infinity The area under the first moment curve (AUMC) AUMC Infinity Predicted Pred Norm by extrapolated to infinity, based on the last predicted Normalized by Dose Dose concentration divided by the dose.

C92336 AUMCIFPS AUMC Infinity The area under the first moment curve (AUMC) AUMC Infinity Predicted Pred Norm by extrapolated to infinity, based on the last predicted Normalized by Surface Area SA concentration divided by the surface area.

C92337 AUMCIFPW AUMC Infinity The area under the first moment curve (AUMC) AUMC Infinity Predicted Pred Norm by extrapolated to infinity, based on the last predicted Normalized by Weight WT concentration divided by the weight.

C85569 AUMCLST AUMC Dosing The area under the moment curve (AUMC) from the Area Under the First Moment Curve to Last Conc time of dosing to the last measurable concentration. From Dosing to Last Concentration

C92326 AUMCLSTB AUMC Dosing The area under the moment curve (AUMC) from the AUMC Dosing to Last Concentration to Last Conc time of dosing to the last measurable concentration Normalized by Body Mass Index Norm by BMI divided by the body mass index.

C92327 AUMCLSTD AUMC Dosing The area under the moment curve (AUMC) from the AUMC Dosing to Last Concentration to Last Conc time of dosing to the last measurable concentration Normalized by Dose Norm by Dose divided by the dose.

C92328 AUMCLSTS AUMC Dosing The area under the moment curve (AUMC) from the AUMC Dosing to Last Concentration to Last Conc time of dosing to the last measurable concentration Normalized by Surface Area Norm by SA divided by the surface area.

C92329 AUMCLSTW AUMC Dosing The area under the moment curve (AUMC) from the AUMC Dosing to Last Concentration to Last Conc time of dosing to the last measurable concentration Normalized by Weight Norm by WT divided by the weight.

C85766 AUMCPEO AUMC % The percentage of the area under the moment curve Observed Area Under the First Extrapolation (AUMC) extrapolated to infinity from Tlast to infinity Moment Curve Percent Obs based on the observed value for concentration at TLast. Extrapolation

C85790 AUMCPEP AUMC % The percentage of the area under the moment curve Predicted Area Under the First Extrapolation (AUMC) extrapolated to infinity from Tlast to infinity Moment Curve Percent Pred based on the predicted value for concentration at Extrapolation TLast.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 322 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C85839 - PKPARMCD - PK Parameters Code Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C85570 AUMCTAU AUMC Over The area under the first moment curve (AUMC) for the Area Under the First Moment Curve Dosing Interval defined interval between doses (TAU). Over Dosing Interval

C92338 AUMCTAUB AUMC Over The area under the first moment curve (AUMC) for the AUMC Over Dosing Interval Dosing Interval defined interval between doses (TAU) divided by the Normalized by Body Mass Index Norm by BMI body mass index.

C92339 AUMCTAUD AUMC Over The area under the first moment curve (AUMC) for the AUMC Over Dosing Interval Dosing Interval defined interval between doses (TAU) divided by the Normalized by Dose Norm by Dose dose.

C92340 AUMCTAUS AUMC Over The area under the first moment curve (AUMC) for the AUMC Over Dosing Interval Dosing Interval defined interval between doses (TAU) divided by the Normalized by Surface Area Norm by SA surface area.

C92341 AUMCTAUW AUMC Over The area under the first moment curve (AUMC) for the AUMC Over Dosing Interval Dosing Interval defined interval between doses (TAU) divided by the Normalized by Weight Norm by WT weight.

C85841 AURCALL AURC All The area under the urinary excretion rate curve Area Under Urinary Excretion Rate (AURC) from time zero to the last measurable rate. Curve All

C92342 AURCALLB AURC All Norm The area under the urinary excretion rate curve AURC All Normalized by Body Mass by BMI (AURC) from time zero to the last measurable rate Index divided by the body mass index.

C92343 AURCALLD AURC All Norm The area under the urinary excretion rate curve AURC All Normalized by Dose by Dose (AURC) from time zero to the last measurable rate divided by the dose.

C92344 AURCALLS AURC All Norm The area under the urinary excretion rate curve AURC All Normalized by Surface by SA (AURC) from time zero to the last measurable rate Area divided by the surface area.

C92345 AURCALLW AURC All Norm The area under the urinary excretion rate curve AURC All Normalized by Weight by WT (AURC) from time zero to the last measurable rate divided by the weight.

C85767 AURCIFO AURC Infinity The area under the urinary excretion rate curve Observed Area Under the Urinary Obs (AURC) extrapolated to infinity, based on the last Excretion Rate Curve infinity observed excretion rate.

C92354 AURCIFOB AURC Infinity The area under the urinary excretion rate curve AURC Infinity Observed Normalized Obs Norm by (AURC) extrapolated to infinity, based on the last by Body Mass Index BMI observed excretion rate, divided by the body mass index.

C92355 AURCIFOD AURC Infinity The area under the urinary excretion rate curve AURC Infinity Observed Normalized Obs Norm by (AURC) extrapolated to infinity, based on the last by Dose Dose observed excretion rate, divided by the dose.

C92356 AURCIFOS AURC Infinity The area under the urinary excretion rate curve AURC Infinity Observed Normalized Obs Norm by SA (AURC) extrapolated to infinity, based on the last by Surface Area observed excretion rate, divided by the surface area.

C92357 AURCIFOW AURC Infinity The area under the urinary excretion rate curve AURC Infinity Observed Normalized Obs Norm by (AURC) extrapolated to infinity, based on the last by Weight WT observed excretion rate, divided by the weight.

C85791 AURCIFP AURC Infinity The area under the urinary excretion rate curve Predicted Area Under the Urinary Pred (AURC) extrapolated to infinity, based on the last Excretion Rate Curve Infinity predicted excretion rate.

C92358 AURCIFPB AURC Infinity The area under the urinary excretion rate curve AURC Infinity Predicted Normalized Pred Norm by (AURC) extrapolated to infinity, based on the last by Body Mass Index BMI predicted excretion rate, divided by the body mass index.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 323 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C85839 - PKPARMCD - PK Parameters Code Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C92359 AURCIFPD AURC Infinity The area under the urinary excretion rate curve AURC Infinity Predicted Normalized Pred Norm by (AURC) extrapolated to infinity, based on the last by Dose Dose predicted excretion rate, divided by the dose.

C92360 AURCIFPS AURC Infinity The area under the urinary excretion rate curve AURC Infinity Predicted Normalized Pred Norm by (AURC) extrapolated to infinity, based on the last by Surface Area SA predicted excretion rate, divided by the surface area.

C92361 AURCIFPW AURC Infinity The area under the urinary excretion rate curve AURC Infinity Predicted Normalized Pred Norm by (AURC) extrapolated to infinity, based on the last by Weight WT predicted excretion rate, divided by the weight.

C85572 AURCINT AURC from T1 The area under the urinary excretion rate curve Area Under the Urinary Excretion to T2 (AURC) over the interval from T1 to T2. Rate Curve from T1 to T2

C92350 AURCINTB AURC from T1 The area under the urinary excretion rate curve AURC from T1 to T2 Normalized by to T2 Norm by (AURC) over the interval from T1 to T2 divided by the Body Mass Index BMI body mass index.

C92351 AURCINTD AURC from T1 The area under the urinary excretion rate curve AURC from T1 to T2 Normalized by to T2 Norm by (AURC) over the interval from T1 to T2 divided by the Dose Dose dose.

C92352 AURCINTS AURC from T1 The area under the urinary excretion rate curve AURC from T1 to T2 Normalized by to T2 Norm by (AURC) over the interval from T1 to T2 divided by the Surface Area SA surface area.

C92353 AURCINTW AURC from T1 The area under the urinary excretion rate curve AURC from T1 to T2 Normalized by to T2 Norm by (AURC) over the interval from T1 to T2 divided by the Weight WT weight.

C85571 AURCLST AURC Dosing to The area under the urinary excretion rate curve Area Under the Urinary Excretion Last Conc (AURC) from time zero to the last measurable rate. Rate Curve From Dosing to Last Concentration

C92346 AURCLSTB AURC Dosing to The area under the urinary excretion rate curve AURC Dosing to Last Concentration Last Conc Norm (AURC) from time zero to the last measurable rate, Normalized by Body Mass Index by BMI divided by the body mass index.

C92347 AURCLSTD AURC Dosing to The area under the urinary excretion rate curve AURC Dosing to Last Concentration Last Conc Norm (AURC) from time zero to the last measurable rate, Normalized by Dose by Dose divided by the dose.

C92348 AURCLSTS AURC Dosing to The area under the urinary excretion rate curve AURC Dosing to Last Concentration Last Conc Norm (AURC) from time zero to the last measurable rate, Normalized by Surface Area by SA divided by the surface area.

C92349 AURCLSTW AURC Dosing to The area under the urinary excretion rate curve AURC Dosing to Last Concentration Last Conc Norm (AURC) from time zero to the last measurable rate, Normalized by Weight by WT divided by the weight.

C85768 AURCPEO AURC % The percentage of the area under the urine excretion Observed Area Under the Urinary Extrapolation rate curve (AURC) extrapolated to infinity observed Excretion Rate Curve Percent Obs from Tlast to infinity. Extrapolation

C85792 AURCPEP AURC % The percentage of the area under the urine excretion Predicted Area Under the Urinary Extrapolation rate curve (AURC) extrapolated to infinity predicted Excretion Rate Curve Percent Pred from Tlast to infinity. Extrapolation

C85644 C0 Initial Conc Initial concentration. Given only for bolus IV models. Initial Concentration

C92383 C0B Initial Conc Initial concentration divided by the body mass index. Initial Concentration Normalized by Norm by BMI Given only for bolus IV models. Body Mass Index

C92384 C0D Initial Conc Initial concentration divided by the dose. Given only Initial Concentration Normalized by Norm by Dose for bolus IV models. Dose

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 324 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C85839 - PKPARMCD - PK Parameters Code Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C92385 C0S Initial Conc Initial concentration divided by the surface area. Given Initial Concentration Normalized by Norm by SA only for bolus IV models. Surface Area

C92386 C0W Initial Conc Initial concentration divided by the weight. Given only Initial Concentration Normalized by Norm by WT for bolus IV models. Weight

C85575 CAVG Average Conc; AUCTAU divided by TAU. Average Concentration Average Concentration

C92367 CAVGB Average Conc AUCTAU divided by TAU and then divided by the body Average Concentration Normalized Norm by BMI mass index. by Body Mass Index

C92368 CAVGD Average Conc AUCTAU divided by TAU and then divided by the dose. Average Concentration Normalized Norm by Dose by Dose

C92369 CAVGS Average Conc AUCTAU divided by TAU and then divided by the Average Concentration Normalized Norm by SA surface area. by Surface Area

C92370 CAVGW Average Conc AUCTAU divided by TAU and then divided by the Average Concentration Normalized Norm by WT weight. by Weight

C85772 CLFO Total CL Obs by The observed total body clearance for extravascular Observed Total Body Clearance by Fract Dose administration based on the fraction of dose absorbed. Fraction of Dose Absorbed

C92399 CLFOB Total CL Obs by The observed total body clearance for extravascular Total Clearance Observed by Fract Dose Norm administration based on the fraction of dose absorbed Fraction Dose Normalized by Body by BMI and divided by the body mass index. Mass Index

C92400 CLFOD Total CL Obs by The observed total body clearance for extravascular Total Clearance Observed by Fract Dose Norm administration based on the fraction of dose absorbed Fraction Dose Normalized by Dose by Dose and divided by the dose.

C92401 CLFOS Total CL Obs by The observed total body clearance for extravascular Total Clearance Observed by Fract Dose Norm administration based on the fraction of dose absorbed Fraction Dose Normalized by by SA and divided by the surface area. Surface Area

C92402 CLFOW Total CL Obs by The observed total body clearance for extravascular Total Clearance Observed by Fract Dose Norm administration based on the fraction of dose absorbed Fraction Dose Normalized by by WT and divided by the weight. Weight

C85796 CLFP Total CL Pred by The predicted total body clearance for extravascular Predicted Total Body Clearance by Fract Dose administration based on the fraction of dose absorbed. Fraction of Dose Absorbed

C92417 CLFPB Total CL Pred by The predicted total body clearance for extravascular Total Clearance Predicted by Fract Dose Norm administration based on the fraction of dose absorbed Fraction Dose Normalized by Body by BMI and divided by the body mass index. Mass Index

C92418 CLFPD Total CL Pred by The predicted total body clearance for extravascular Total Clearance Predicted by Fract Dose Norm administration based on the fraction of dose absorbed Fraction Dose Normalized by Dose by Dose and divided by the dose.

C92419 CLFPS Total CL Pred by The predicted total body clearance for extravascular Total Clearance Predicted by Fract Dose Norm administration based on the fraction of dose absorbed Fraction Dose Normalized by by SA and divided by the surface area. Surface Area

C92420 CLFPW Total CL Pred by The predicted total body clearance for extravascular Total Clearance Predicted by Fract Dose Norm administration based on the fraction of dose absorbed Fraction Dose Normalized by by WT and divided by the weight. Weight

C85773 CLO Total CL Obs The observed total body clearance for intravascular Observed Total Body Clearance Rate administration.

C92403 CLOB Total CL Obs The observed total body clearance for intravascular Total Clearance Observed Norm by BMI administration divided by the body mass index. Normalized by Body Mass Index

C92404 CLOD Total CL Obs The observed total body clearance for intravascular Total Clearance Observed Norm by Dose administration divided by the dose. Normalized by Dose

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 325 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C85839 - PKPARMCD - PK Parameters Code Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C92405 CLOS Total CL Obs The observed total body clearance for intravascular Total Clearance Observed Norm by SA administration divided by the surface area. Normalized by Surface Area

C92406 CLOW Total CL Obs The observed total body clearance for intravascular Total Clearance Observed Norm by WT administration divided by the weight. Normalized by Weight

C85797 CLP Total CL Pred The predicted total body clearance for intravascular Predicted Total Body Clearance Rate administration.

C92421 CLPB Total CL Pred The predicted total body clearance for intravascular Total Clearance Predicted Norm by BMI administration divided by the body mass index. Normalized by Body Mass Index

C92422 CLPD Total CL Pred The predicted total body clearance for intravascular Total Clearance Predicted Norm by Dose administration divided by the dose. Normalized by Dose

C92423 CLPS Total CL Pred The predicted total body clearance for intravascular Total Clearance Predicted Norm by SA administration divided by the surface area. Normalized by Surface Area

C92424 CLPW Total CL Pred The predicted total body clearance for intravascular Total Clearance Predicted Norm by WT administration divided by the weight. Normalized by Weight

C85655 CLST Last Conc The concentration corresponding to Tlast. Last Concentration

C92387 CLSTB Last Conc Norm The concentration corresponding to Tlast divided by Last Concentration Normalized by by BMI the body mass index. Body Mass Index

C92388 CLSTD Last Conc Norm The concentration corresponding to Tlast divided by Last Concentration Normalized by by Dose the dose. Dose

C92389 CLSTS Last Conc Norm The concentration corresponding to Tlast divided by Last Concentration Normalized by by SA the surface area. Surface Area

C92390 CLSTW Last Conc Norm The concentration corresponding to Tlast divided by Last Concentration Normalized by by WT the weight. Weight

C70918 CMAX Max Conc The maximum concentration occurring at Tmax. Cmax

C92371 CMAXB Max Conc Norm The maximum concentration occurring at Tmax, Maximum Concentration Normalized by BMI divided by the body mass index. by Body Mass Index

C85698 CMAXD Max Conc Norm The maximum concentration occurring at Tmax, Maximum Concentration Dose by Dose divided by the dose. Normalized

C92372 CMAXS Max Conc Norm The maximum concentration occurring at Tmax, Maximum Concentration Normalized by SA divided by the surface area. by Surface Area

C92373 CMAXW Max Conc Norm The maximum concentration occurring at Tmax, Maximum Concentration Normalized by WT divided by the weight. by Weight

C85579 CMIN Min Conc The minimum concentration between dose time and Cmin dose time plus Tau (at Tmin).

C92374 CMINB Min Conc Norm The minimum concentration between dose time and Minimum Concentration Normalized by BMI dose time plus Tau (at Tmin) divided by the body mass by Body Mass Index index.

C92375 CMIND Min Conc Norm The minimum concentration between dose time and Minimum Concentration Normalized by Dose dose time plus Tau (at Tmin) divided by the dose. by Dose

C92376 CMINS Min Conc Norm The minimum concentration between dose time and Minimum Concentration Normalized by SA dose time plus Tau (at Tmin) divided by the surface by Surface Area area.

C92377 CMINW Min Conc Norm The minimum concentration between dose time and Minimum Concentration Normalized by WT dose time plus Tau (at Tmin) divided by the weight. by Weight

C92378 CNTHDOS Conc After the The concentration at the Nth dose. Concentration After the Nth Dose Nth Dose

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 326 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C85839 - PKPARMCD - PK Parameters Code Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C92379 CNTHDOSB Conc After the The concentration at the Nth dose divided by the body Concentration After the Nth Dose by Nth Dose by mass index. Body Mass Index BMI

C92380 CNTHDOSD Conc After the The concentration at the Nth dose divided by the dose. Concentration After the Nth Dose by Nth Dose by Dose Dose

C92381 CNTHDOSS Conc After the The concentration at the Nth dose divided by the Concentration After the Nth Dose by Nth Dose by SA surface area. Surface Area

C92382 CNTHDOSW Conc After the The concentration at the Nth dose divided by the Concentration After the Nth Dose by Nth Dose by WT weight. Weight

C85821 CORRXY Correlation The correlation between time (X) and log Time and Log Concentration Between TimeX concentration (Y) for the points used in the estimation Correlation and Log ConcY of lambda z.

C85656 ERLST Last Meas The last measurable (positive) excretion rate. Last Measurable Observed Excretion Excretion Rate Rate

C92391 ERLSTB Last Meas The last measurable (positive) excretion rate divided Last Measurable Excretion Rate Excretion Rate by the body mass index. Normalized by Body Mass Index Norm by BMI

C92392 ERLSTD Last Meas The last measurable (positive) excretion rate divided Last Measurable Excretion Rate Excretion Rate by the dose. Normalized by Dose Norm by Dose

C92393 ERLSTS Last Meas The last measurable (positive) excretion rate divided Last Measurable Excretion Rate Excretion Rate by the surface area. Normalized by Surface Area Norm by SA

C92394 ERLSTW Last Meas The last measurable (positive) excretion rate divided Last Measurable Excretion Rate Excretion Rate by the weight. Normalized by Weight Norm by WT

C85699 ERMAX Max Obs The maximum observed excretion rate. Maximum Observed Excretion Rate Excretion Rate

C92395 ERMAXB Max Obs The maximum observed excretion rate divided by the Maximum Observed Excretion Rate Excretion Rate body mass index. Normalized by Body Mass Index Norm by BMI

C92396 ERMAXD Max Obs The maximum observed excretion rate divided by the Maximum Observed Excretion Rate Excretion Rate dose. Normalized by Dose Norm by Dose

C92397 ERMAXS Max Obs The maximum observed excretion rate divided by the Maximum Observed Excretion Rate Excretion Rate surface area. Normalized by Surface Area Norm by SA

C92398 ERMAXW Max Obs The maximum observed excretion rate divided by the Maximum Observed Excretion Rate Excretion Rate weight. Normalized by Weight Norm by WT

C85823 ERTMAX Time of Max The midpoint of collection interval associated with the Time of Maximum Observed Excretion Rate maximum observed excretion rate. Excretion Rate

C85581 FLUCP Fluctuation% The difference between Cmin and Cmax standardized Concentration Variability Between to Cavg, between dose time and Tau. Dose Time and Tau

C85652 LAMZ Lambda z The first order rate constant associated with the Lambda Z terminal (log-linear) portion of the curve.

C85818 LAMZHL Half-Life Terminal half-life. Terminal Half Life Lambda z

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 327 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C85839 - PKPARMCD - PK Parameters Code Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C85653 LAMZLL Lambda z Lower The lower limit on time for values to be included in the Lambda Z Time Lower Limit Limit calculation of Lambda z.

C85816 LAMZNPT Number of The number of time points used in computing Lambda Sum of Lambda Z Timepoints Points for z. Lambda z

C85654 LAMZUL Lambda z Upper The upper limit on time for values to be included in the Lambda Z Time Upper Limit Limit calculation of Lambda z.

C85580 MIDPTLST Midpoint of The midpoint of collection interval, which is Collection Interval Midpoint Entire Collection associated with last Measurable rate. Interval

C85769 MRTIFO MRT Infinity The observed mean residence time (MRT) extrapolated Observed Mean Residence Time Obs to infinity. Infinity

C85793 MRTIFP MRT Infinity The predicted mean residence time (MRT) Predicted Mean Residence Time Pred extrapolated to infinity. Infinity

C85700 MRTLST MRT Last Mean residence time (MRT) from the time of dosing Mean Residence Time Last to the time of the last measurable concentration.

C85542 R2 R Squared The goodness of fit statistic for the terminal R Squared elimination phase.

C85553 R2ADJ R Squared The goodness of fit statistic for the terminal Adjusted R Squared Adjusted elimination phase, adjusted for the number of time points used in the estimation of Lambda z.

C85832 RECAMT Amount The cumulative amount recovered from the specimen Amount Recovered Recovered type specified in PPSPEC, from dosing to end of the current collection interval.

C92363 RECAMTB Amount The cumulative amount recovered from the specimen Amount Recovered Normalized by Recovered Norm type specified in PPSPEC, from dosing to end of the Body Mass Index by BMI current collection interval divided by the body mass index.

C92364 RECAMTD Amount The cumulative amount recovered from the specimen Amount Recovered Normalized by Recovered Norm type specified in PPSPEC, from dosing to end of the Dose by Dose current collection interval divided by the dose.

C92365 RECAMTS Amount The cumulative amount recovered from the specimen Amount Recovered Normalized by Recovered Norm type specified in PPSPEC, from dosing to end of the Surface Area by SA current collection interval divided by the surface area.

C92366 RECAMTW Amount The cumulative amount recovered from the specimen Amount Recovered Normalized by Recovered Norm type specified in PPSPEC, from dosing to end of the Weight by WT current collection interval divided by the weight.

C85777 RECPCT Percent The percentage of the dose that is recovered from the Percent Recovered Recovered specimen type specified in PPSPEC, from dosing to end of the current collection interval.

C92413 RECPCTB Percent The percentage of the dose that is recovered from the Percent Recovered Normalized by Recovered Norm specimen type specified in PPSPEC, from dosing to Body Mass Index by BMI end of the current collection interval divided by the body mass index.

C92414 RECPCTD Percent The percentage of the dose that is recovered from the Percent Recovered Normalized by Recovered Norm specimen type specified in PPSPEC, from dosing to Dose by Dose end of the current collection interval divided by the dose.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 328 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C85839 - PKPARMCD - PK Parameters Code Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C92415 RECPCTS Percent The percentage of the dose that is recovered from the Percent Recovered Normalized by Recovered Norm specimen type specified in PPSPEC, from dosing to Surface Area by SA end of the current collection interval divided by the surface area.

C92416 RECPCTW Percent The percentage of the dose that is recovered from the Percent Recovered Normalized by Recovered Norm specimen type specified in PPSPEC, from dosing to Weight by WT end of the current collection interval divided by the weight.

C85824 TLAG Time Until First The time prior to the first measurable (non-zero) Time until First Nonzero Nonzero Conc concentration. Concentration

C85822 TLST Time of Last The time of the last measurable (positive) Time of Last Nonzero Concentration Nonzero Conc concentration.

C70919 TMAX Time of CMAX The time of maximum observed concentration sampled Tmax Observation during a dosing interval.

C85825 TMIN Time of CMIN The time of minimum concentration sampled during a Tmin Observation dosing interval.

C85817 VOLPK Sum of Urine The sum of urine volumes that are used for PK Sum Urine Volume Vol Used for PK parameters. Parameters

C85775 VZFO Vol Dist of Fract The observed volume of distribution of the absorbed Observed Volume of Distribution of Dose Obs fraction associated with the terminal slope following Absorbed Fraction extravascular administration, where F equals the fraction of dose absorbed.

C92410 VZFOB Vol Dist of Fract The observed volume of distribution of the absorbed Volume of Distribution of Fraction Dose Obs Norm fraction associated with the terminal slope following Dose Observed Normalized by Body by BMI extravascular administration, where F equals the Mass Index fraction of dose absorbed, divided by the body mass index.

C92411 VZFOS Vol Dist of Fract The observed volume of distribution of the absorbed Volume of Distribution of Fraction Dose Obs Norm fraction associated with the terminal slope following Dose Observed Normalized by by SA extravascular administration, where F equals the Surface Area fraction of dose absorbed, divided by the surface area.

C92412 VZFOW Vol Dist of Fract The observed volume of distribution of the absorbed Volume of Distribution of Fraction Dose Obs Norm fraction associated with the terminal slope following Dose Observed Normalized by by WT extravascular administration, where F equals the Weight fraction of dose absorbed, divided by the weight.

C85799 VZFP Vol Dist of Fract The predicted volume of distribution of the absorbed Predicted Volume of Distribution of Dose Pred fraction associated with the terminal slope following Absorbed Fraction extravascular administration, where F equals the fraction of dose absorbed.

C92428 VZFPB Vol Dist of Fract The predicted volume of distribution of the absorbed Volume of Distribution of Fraction Dose Pred Norm fraction associated with the terminal slope following Dose Predicted Normalized by Body by BMI extravascular administration, where F equals the Mass Index fraction of dose absorbed, divided by the body mass index.

C92429 VZFPS Vol Dist of Fract The predicted volume of distribution of the absorbed Volume of Distribution of Fraction Dose Pred Norm fraction associated with the terminal slope following Dose Predicted Normalized by by SA extravascular administration, where F equals the Surface Area fraction of dose absorbed, divided by the surface area.

C92430 VZFPW Vol Dist of Fract The predicted volume of distribution of the absorbed Volume of Distribution of Fraction Dose Pred Norm fraction associated with the terminal slope following Dose Predicted Normalized by by WT extravascular administration, where F equals the Weight fraction of dose absorbed, divided by the weight.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 329 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C85839 - PKPARMCD - PK Parameters Code Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C85774 VZO Vz Obs The observed volume of distribution associated with Observed Volume of Distribution the terminal slope following intravascular administration.

C92407 VZOB Vz Obs Norm by The observed volume of distribution associated with Volume of Distribution Observed BMI the terminal slope following intravascular Normalized by Body Mass Index administration divided by the body mass index.

C92408 VZOS Vz Obs Norm by The observed volume of distribution associated with Volume of Distribution Observed SA the terminal slope following intravascular Normalized by Surface Area administration divided by the surface area.

C92409 VZOW Vz Obs Norm by The observed volume of distribution associated with Volume of Distribution Observed WT the terminal slope following intravascular Normalized by Weight administration divided by the weight.

C85798 VZP Vz Pred The predicted volume of distribution associated with Predicted Volume of Distribution the terminal slope following intravascular administration.

C92425 VZPB Vz Pred Norm by The predicted volume of distribution associated with Volume of Distribution Predicted BMI the terminal slope following intravascular Normalized by Body Mass Index administration divided by the body mass index.

C92426 VZPS Vz Pred Norm by The predicted volume of distribution associated with Volume of Distribution Predicted SA the terminal slope following intravascular Normalized by Surface Area administration divided by the surface area.

C92427 VZPW Vz Pred Norm by The predicted volume of distribution associated with Volume of Distribution Predicted WT the terminal slope following intravascular Normalized by Weight administration divided by the weight.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 330 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C85494 - PKUNIT - PK Parameter Units of Measure Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C66966 /h Per Hour A rate of occurrences of something within a period of Per Hour time equal to sixty minutes.

C85645 IU/day IU/d International units per day. International Unit per Day

C85646 IU/h IU/h International units per hour. International Unit per Hour

C85647 IU/min IU/min International units per minute. International Unit per Minute

C85648 IU/s IU/sec; IU/s International units per second. International Unit per Second

C48505 L Liter A unit of volume equal to a cubic decimeter, or one Liter thousandth of cubic meter, or 1000 cubic centimeters, or approximately 61.023 744 cubic inches.(NCI)

C69110 L/day Liters per day. Liter per Day

C85657 L/g/day mL/mg/day; Liters per gram per day. Liter per Gram per Day uL/ug/day; L/day/g; L/g/d

C85658 L/g/h L/h/g; mL/mg/h; Liters per gram per hour. Liter per Gram per Hour uL/ug/h; mL/h/mg; uL/h/ug; L/g/h

C85659 L/g/min mL/mg/min; Liters per gram per minute. Liter per Gram per Minute uL/ug/min; L/min/g; L/g/min

C85660 L/g/s L/g/sec; Liters per gram per second. Liter per Gram per Second mL/mg/s; uL/ug/s; L/s/g; mL/mg/sec; uL/ug/sec; L/sec/g; L/g/s

C69160 L/h L/h Liters per hour. Liter per Hour

C73755 L/kg/day Milliliter per Liters per kilogram per day. Milliliter per Gram per Day Gram per Day; mL/g/day; uL/mg/day; L/day/kg; mL/day/g; uL/day/mg; L/kg/d

C73756 L/kg/h Milliliters per gram per hour. Milliliter per Gram per Hour

C73757 L/kg/min Milliliters per gram per minute. Milliliter per Gram per Minute

C85664 L/kg/s L/kg/sec; mL/g/s; Liters per kilogram per second. Liter per Kilogram per Second uL/mg/s; L/s/kg; L/sec/kg; mL/s/g; uL/s/mg; L/kg/s

C85672 L/mg/day mL/ug/day; Liters per milligram per day. Liter per Milligram per Day L/day/mg; mL/day/ug; L/mg/d

C85673 L/mg/h mL/ug/h; L/h/mg; Liters per milligram per hour. Liter per Milligram per Hour mL/h/ug; L/mg/h

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 331 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C85494 - PKUNIT - PK Parameter Units of Measure Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C85674 L/mg/min mL/ug/min; Liters per milligram per minute. Liter per Milligram per Minute L/min/mg; mL/min/ug; L/mg/min

C85675 L/mg/s mL/ug/s; L/s/mg; Liters per milligram per second. Liter per Milligram per Second mL/s/ug; mL/ug/sec; L/sec/mg; mL/sec/ug; L/mg/s

C67388 L/min Liters per A unit of volumetric flow rate defined as the rate at Liter per Minute Minute which one liter of matter travels during the period of time equal to one minute.(NCI)

C85676 L/mmol/day mL/umol/day; Liters per millimole per day. Liter per Millimole per Day L/day/mmol; mL/day/umol; L/mmol/d

C85677 L/mmol/h mL/umol/h; Liters per millimole per hour. Liter per Millimole per Hour L/h/mmol; mL/h/umol; L/mmol/h

C85678 L/mmol/min mL/umol/min; Liters per millimole per minute. Liter per Millimole per Minute L/min/mmol; mL/min/umol; L/mmol/min

C85679 L/mmol/s L/mmol/sec; Liters per millimole per second. Liter per Millimole per Second L/s/mmol; L/sec/mmol; mL/umol/s; mL/umol/sec; mL/s/umol; mL/sec/umoL; L/mmol/s

C85680 L/mol mL/mmol; Liters per mole. Liter per Mole uL/umol; L/mol

C85681 L/mol/day L/day/mol; Liters per mole per day. Liter per Mole per Day mL/mmol/day; uL/umol/day; mL/day/mmol; uL/day/umol; L/mol/d

C85682 L/mol/h L/h/mol; Liters per mole per hour. Liter per Mole per Hour mL/mmol/h; uL/umol/h; mL/h/mmol; uL/h/umol; L/mol/h

C85683 L/mol/min L/min/mol; Liters per mole per minute. Liter per Mole per Minute mL/mmol/min; uL/umol/min; mL/min/mmol; uL/min/umol; L/mol/min

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 332 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C85494 - PKUNIT - PK Parameter Units of Measure Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C85684 L/mol/s L/mol/sec; Liters per mole per second. Liter per Mole per Second L/s/mol; L/sec/mol; mL/mmol/s; mL/mmol/sec; mL/s/mmol; mL/sec/mmol; L/mol/s

C85685 L/ng/day L/day/ng; Liters per nanogram per day. Liter per Nanogram per Day mL/pg/day; mL/day/pg; L/ng/d

C85686 L/ng/h L/h/ng; mL/pg/h; Liters per nanogram per hour. Liter per Nanogram per Hour mL/h/pg; L/ng/h

C85687 L/ng/min L/min/ng; Liters per nanogram per minute. Liter per Nanogram per Minute mL/pg/min; mL/min/pg; L/ng/min

C85688 L/ng/s L/s/ng; L/ng/sec; Liters per nanogram per second. Liter per Nanogram per Second L/sec/ng; mL/pg/s; mL/s/pg; mL/pg/sec; mL/sec/pg; L/ng/s

C85689 L/nmol/day mL/pmol/day; Liters per nanomole per day. Liter per Nanomole per Day L/day/nmol; mL/day/pmol; L/nmol/d

C85690 L/nmol/h mL/pmol/h; Liters per nanomole per hour. Liter per Nanomole per Hour L/h/nmol; mL/h/pmol; L/nmol/h

C85691 L/nmol/min mL/pmol/min; Liters per nanomole per minute. Liter per Nanomole per Minute L/min/nmol; mL/min/pmol; L/nmol/min

C85692 L/nmol/s L/nmol/sec; Liters per nanomole per second. Liter per Nanomole per Second mL/pmol/s; mL/s/pmol; L/s/nmol; L/sec/nmol; L/nmol/s

C85693 L/pg/day L/day/pg; L/pg/d Liters per picogram per day. Liter per Picogram per Day

C85694 L/pg/h L/h/pg; L/pg/h Liters per picogram per hour. Liter per Picogram per Hour

C85695 L/pg/min L/min/pg; Liters per picogram per minute. Liter per Picogram per Minute L/pg/min

C85696 L/pg/s L/pg/sec; L/s/pg; Liters per picogram per second. Liter per Picogram per Second L/sec/pg; L/pg/s

C67390 L/s L/sec Liters per second. Liter per Second

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 333 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C85494 - PKUNIT - PK Parameter Units of Measure Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C85665 L/ug/day L/mcg/day; Liters per microgram per day. Liter per Microgram per Day L/day/ug; L/day/mcg; mL/day/ng; mL/ng/day

C85662 L/ug/h L/mcg/h; L/h/ug; Liters per microgram per hour. Liter per Microgram per Hour L/h/mcg; mL/h/ng; mL/ng/h; L/ug/h

C85666 L/ug/min L/mcg/min; Liters per microgram per minute. Liter per Microgram per Minute L/min/ug; L/min/mcg; mL/min/ng; mL/ng/min

C85667 L/ug/s L/ug/sec; L/s/ug; Liters per microgram per second. Liter per Microgram per Second L/ug/s; L/sec/ug; L/mcg/sec; L/s/mcg; L/mcg/s; L/sec/mcg; mL/ng/s; mL/s/ng

C85668 L/umol/day L/mcmol/day; Liters per micromole per day. Liter per Micromole per Day L/day/umol; L/day/mcmol; L/umol/d

C85669 L/umol/h L/mcmol/h; Liters per micromole per hour. Liter per Micromole per Hour L/h/umol; L/h/mcmol; L/umol/h

C85670 L/umol/min L/mcmol/min; Liters per micromole per minute. Liter per Micromole per Minute L/min/umol; L/min/mcmol; L/umol/min

C85671 L/umol/s L/mcmol/s; Liters per micromole per second. Liter per Micromole per Second L/umol/sec; L/s/umol; L/sec/umol; L/mcmol/sec; L/sec/mcmol; mL/nmol/s; mL/s/nmol; L/umol/s

C85583 day*fg/mL pg*day/L; Days times femtograms per milliliter. Day Times Femtogram per Milliliter day*pg/L; fg*day/mL; d*fg/mL

C85584 day*g/mL g*day/mL; Days times grams per milliliter. Day Times Gram per Milliliter day*kg/L; kg*day/L; d*g/mL

C85585 day*kg/mL kg*day/mL; Days times kilograms per milliliter. Day Times Kilogram per Milliliter g*day/uL; day*g/uL; d*kg/mL

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 334 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C85494 - PKUNIT - PK Parameter Units of Measure Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C85588 day*mg/mL mg*day/mL; Days times milligrams per milliliter. Day Times Milligram per Milliliter day*g/L; g*day/L; day*ug/uL; ug*day/uL; d*mg/mL

C85589 day*mmol/mL mmol*day/mL; Days times millimoles per milliliter. Day Times Millimole per Milliliter day*mol/L; mol*day/L; day*umol/uL; umol*day/uL; d*mmol/mL

C85590 day*mol/mL mol*day/mL; Days times moles per milliliter. Day Times Mole per Milliliter d*mol/mL

C85591 day*ng/mL ng*day/mL; Days times nanograms per milliliter. Day Times Nanogram per Milliliter day*ug/L; ug*day/L; d*ng/mL

C85592 day*nmol/mL nmol*day/mL; Days times nanomoles per milliliter. Day Times Nanomole per Milliliter day*umol/L; umol*day/L; d*nmol/mL

C85593 day*pg/mL pg*day/mL; Days times picograms per milliliter. Day Times Picogram per Milliliter day*ng/L; ng*day/L; d*pg/mL

C85594 day*pmol/mL nmol*day/L; Days times picomoles per milliliter. Day Times Picomole per Milliliter day*nmol/L; pmol*day/mL; d*pmol/mL

C85586 day*ug/mL ug*day/mL; Days times micrograms per milliliter. Day Times Microgram per Milliliter day*mg/L; mg*day/L; day*mcg/mL; mcg*day/mL

C85587 day*umol/mL umol*day/mL; Days times micromoles per milliliter. Day Times Micromole per Milliliter day*mmol/L; mmol*day/L; day*mcmol/mL; mcmol*day/mL; d*umol/mL

C85597 fg/mL pg/L; fg/mL Femtograms per milliliter. Femtogram per Milliliter

C48155 g Gram A metric unit of mass equal to one one thousandth of a Gram kilogram. (NCI)

C85600 g/day gram/day; g/d Grams per day. Gram per Day

C85601 g/h gram/h; g/h Grams per hour. Gram per Hour

C64566 g/mL Kilogram per A unit of mass concentration defined as the Kilogram per Liter Liter; g/mL; concentration of one kilogram of a substance in unit Gram per volume of the mixture equal to one liter. The concept Milliliter; also refers to the unit of mass density (volumic mass) gram/mL; kg/L; defined as the density of substance which mass equal mg/uL to one kilogram occupies the volume one liter.(NCI)

C85602 g/min gram/min; g/min Grams per minute. Gram per Minute

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 335 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C85494 - PKUNIT - PK Parameter Units of Measure Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C85603 g/s gram/sec; g/sec; Grams per second. Gram per Second gram/s; g/s

C85611 h*fg/mL pg*h/L; h*pg/L; Hours times femtograms per milliliter. Hour Times Femtogram per fg*h/mL; Milliliter h*fg/mL

C85612 h*fmol/mL pmol*h/L; Hours times femtomoles per milliliter. Hour Times Femtomole per h*pmol/L; Milliliter fmol*h/mL; h*fmol/mL

C85613 h*g/mL g*h/mL; h*kg/L; Hours times grams per milliliter. Hour Times Gram per Milliliter kg*h/L; h*g/mL

C85614 h*kg/mL kg*h/mL; Hours times kilograms per milliliter. Hour Times Kilogram per Milliliter g*h/uL; h*g/uL; h*kg/mL

C85620 h*mg/L/mg mg*h/L/mg; Hours times milligrams per liter per milligram. Hour Times Milligram per Liter per h*mg/mg/L; Milligram mg*h/mg/L; h*mg/L/mg

C85621 h*mg/mL mg*h/mL; h*g/L; Hours times milligrams per milliliter. Hour Times Milligram per Milliliter g*h/L; ug*h/uL; h*ug/uL; h*mg/mL

C85622 h*mmol/mL mmol*h/mL; Hours times millimoles per milliliter. Hour Times Millimole per Milliliter h*mol/L; mol*h/L; umol*h/uL; h*umol/uL; h*mmol/mL

C85623 h*mol/mL mol*h/mL; Hours times moles per milliliter. Hour Times Mole per Milliliter h*mol/mL

C85624 h*ng/mL ng*h/mL; Hours times nanograms per milliliter. Hour Times Nanogram per Milliliter h*ug/L; ug*h/L; h*ng/mL

C85630 h*ng/mL*kg ng*h/mL*kg; Hours times nanograms per milliliter times kilogram. Hour Times Nanogram per Milliliter h*ng/kg*mL; Times Kilogram ng*h/kg*mL; h*ng/mL*kg

C85625 h*ng/mL/g ng*h/mL/g; Hours times nanograms per milliliter per gram. Hour Times Nanogram per Milliliter h*ng/g/mL; per Gram ng*h/g/mL; h*ng/mL/g

C85626 h*ng/mL/kg ng*h/mL/kg; Hours times nanograms per milliliter per kilogram. Hour Times Nanogram per Milliliter ng*h/kg/mL; per Kilogram h*ng/kg/mL; h*ng/mL/kg

C85627 h*ng/mL/mg ng*h/mL/mg; Hours times nanograms per milliliter per milligram. Hour Times Nanogram per Milliliter h*ng/mg/mL; per Milligram ng*h/mg/mL; h*ng/mL/mg

C85628 h*ng/mL/mg/kg ng*h/mL/mg/kg; Hours times nanograms per milliliter per milligram Hour Times Nanogram per Milliliter h*ng/mL/mg per kilogram. per Milligram per Kilogram

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 336 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C85494 - PKUNIT - PK Parameter Units of Measure Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C85629 h*ng/mL/mg/m2 h*ng/mL/mg/ Hours times nanograms per milliliter per milligram Hour Times Nanogram per Milliliter m^2; per meter squared. per Milligram per Meter Squared h*ng/mL/mg/m* m; ng*h/mL/mg/m2

C85631 h*nmol/L/umol h*nmol/L/ Hours times nanomoles per liter per micromole. Hour Times Nanomole per Liter per mcmol; Micromole nmol*h/L/umol; h*nmol/umol/L; nmol*h/umol/L

C85632 h*nmol/mL umol*h/L; Hours times nanomoles per milliliter. Hour Times Nanomole per Milliliter h*umol/L; nmol*h/mL; h*nmol/mL

C85634 h*nmol/mL/mg nmol*h/mL/mg; Hours times nanomoles per milliliter per milligram. Hour Times Nanomole per Milliliter h*nmol/mg/mL; per Milligram nmol*h/mg/mL; h*nmol/mL/mg

C85635 h*pg/mL pg*h/mL; Hours times picograms per milliliter. Hour Times Picogram per Milliliter h*ng/L; ng*h/L; h*pg/mL

C85636 h*pg/mL/kg pg*h/mL/kg; Hours times picograms per milliliter per kilogram. Hour Times Picogram per Milliliter h*pg/kg/mL; per Kilogram pg*h/kg/mL; h*pg/mL/kg

C85638 h*pg/mL/mg pg*h/mL/mg; Hours times picograms per milliliter per milligram. Hour Times Picogram per Milliliter h*pg/mg/mL; per Milligram pg*h/mg/mL; h*pg/mL/mg

C85637 h*pg/mL/ug h*pg/mL/mcg; Hours times picograms per milliliter per microgram. Hour Times Picogram per Milliliter pg*h/mL/ug; per Microgram h*pg/ug/mL; pg*h/ug/mL

C85639 h*pmol/L/ug pmol*h/L/ug; Hours times picomoles per liter per microgram. Hour Times Picomole per Liter per h*pmol/L/mcg; Microgram h*pmol/ug/L; pmol*h/ug/L

C85640 h*pmol/mL pmol*h/mL; Hours times picomoles per milliliter. Hour Times Picomole per Milliliter h*nmol/L; nmol*h/L; h*pmol/mL

C85641 h*pmol/mL/mg pmol*h/mL/mg; Hours times picomoles per milliliter per milligram. Hour Times Picomole per Milliliter h*pmol/mg/mL; per Milligram pmol*h/mg/mL; h*pmol/mL/mg

C85615 h*ug/mL mg*h/L; h*mg/L; Hours times micrograms per milliliter. Hour Times Microgram per h*ng/uL; Milliliter ng*h/uL; h*ug/mL; h*mcg/mL; mcg*h/mL

C85617 h*ug/mL/mg ug*h/mL/mg; Hours times micrograms per milliliter per milligram. Hour Times Microgram per h*mcg/mL/mg; Milliliter per Milligram h*ug/mg/mL; ug*h/mg/mL

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 337 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C85494 - PKUNIT - PK Parameter Units of Measure Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C85618 h*umol/mL mmol*h/L; Hours times micromoles per milliliter. Hour Times Micromole per h*mmol/L; Milliliter umol*h/mL; h*mcmol/mL; mcmol*h/mL; h*umol/mL

C85606 h2*mg/mL mg*h2/mL; Hours squared times milligrams per milliliter. Hour Squared Times Milligram per h^2*mg/mL; Milliliter h*h*mg/mL; h2*g/L; h2*ug/uL

C85607 h2*mmol/mL mmol*h2/mL; Hours squared times millimoles per milliliter. Hour Squared Times Millimole per h^2*mmol/mL; Milliliter h*h*mmol/mL; h2*mol/L; h2*umol/uL

C85608 h2*ng/mL ng*h2/mL; Hours squared times nanograms per milliliter. Hour Squared Times Nanogram per h^2*ng/mL; Milliliter h*h*ng/mL; h2*ug/L

C85609 h2*pg/mL pg*h2/mL; Hours squared times picogram per milliliter. Hour Squared Times Picogram per h^2*pg/mL; Milliliter h*h*pg/mL; h2*ng/L

C85610 h2*pmol/mL pmol*h2/mL; Hours squared times picomoles per milliliter. Hour Squared Times Picomole per h^2*pmol/mL; Milliliter h*h*pmol/mL; h2*nmol/L

C85604 h2*ug/mL ug*h2/mL; Hours squared times micrograms per milliliter. Hour Squared Times Microgram per h^2*ug/mL; Milliliter h*h*ug/mL; h2*mcg/mL; h2*mg/L

C85605 h2*umol/mL umol*h2/mL; Hours squared times micromoles per milliliter. Hour Squared Times Micromole per h^2*umol/mL; Milliliter h*h*umol/mL; h2*mcmol/mL; h2*mmol/L

C67376 mIU/mL International Unit of arbitrary substance concentration (biologic International Unit per Liter Unit per Liter; activity concentration) defined as the concentration of IU/L; mIU/mL one international unit per one liter of system volume.(NCI)

C28254 mL Milliliter; cm3 The unit of volume equal to one thousandth of a liter, Milliliter one cubic centimeter, 10E-6 cubic meter, or approximately to 0.061 023 7 cubic inch.(NCI)

C73753 mL/day Milliliters per day. Milliliter per Day

C66962 mL/h Milliliters per A unit of volumetric flow rate defined as the rate at Milliliter per Hour Hour which one milliliter of matter travels during the period of time equal to one hour.(NCI)

C73758 mL/kg/day Milliliter per Milliliters per kilogram per day. Milliliter per Kilogram per Day Kilogram per Day

C73759 mL/kg/h Milliliter per Milliliters per kilogram per hour. Milliliter per Kilogram per Hour Kilogram per Hour

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 338 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C85494 - PKUNIT - PK Parameter Units of Measure Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C73760 mL/kg/min Milliliter per Milliliters per kilogram per minute. Milliliter per Kilogram per Minute Kilogram per Minute; uL/g/min; mL/min/kg; uL/min/g; mL/kg/min

C85715 mL/kg/s mL/sec/kg; Milliliters per kilogram per second. Milliliter per Kilogram per Second mL/s/kg; mL/kg/sec; mL/kg/s

C64777 mL/min Milliliters per A metric unit of volumetric flow rate defined as the Milliliter per Minute Minute rate at which one milliliter of matter travels during the period of time equal to one minute.(NCI)

C85716 mL/mol/day uL/mmol/day; Milliliters per mole per day. Milliliter per Mole per Day mL/day/mol; uL/day/mmol; mL/mol/d

C85717 mL/mol/h uL/mmol/h; Milliliters per mole per hour. Milliliter per Mole per Hour mL/h/mol; uL/h/mmol; mL/mol/h

C85718 mL/mol/min uL/mmol/min; Milliliters per mole per minute. Milliliter per Mole per Minute mL/min/mol; uL/min/mmol; mL/mol/min

C85719 mL/mol/s mL/sec/mol; Milliliters per mole per second. Milliliter per Mole per Second mL/s/mol; mL/mol/sec; mL/mol/s

C69073 mL/s mL/sec Milliliters per second. Milliliter per Second

C28253 mg Milligram The unit of mass equal to one thousandth of a gram or Milligram 1000 micrograms. One milligram equals approximately 0.015432 grain or 35.274 x 10E-6 ounce.(NCI)

C85710 mg/L/mg mg/mg/L; Milligrams per liter per milligram. Milligram per Liter per Milligram mg/L/mg

C67399 mg/day Milligram per A unit of measure referring to the ratio between mass Milligram per 24 Hours Day expressed in milligrams per day.(NCI)

C66969 mg/h Milligram per A unit of mass flow rate equivalent to the rate at which Milligram per Hour Hour one thousandth of a gram of matter travels to a given object or space over a period of time equal to one hour.(NCI)

C42576 mg/mL g/L; Gram per A unit of mass concentration defined as the Kilogram per Cubic Meter Liter; kg/m3; concentration of one kilogram of a substance per unit Kilogram per volume of the mixture equal to one cubic meter, or the Cubic Metre; concentration of one milligram of a substance per unit Microgram per volume of the mixture equal to one milliliter, or one Microliter; gram of a substance per one liter of the mixture. It is Milligram per also a unit of mass density (volumic mass) defined as Milliliter; ug/uL; the density of substance which mass equal to one mg/mL milligram occupies the volume one milliliter.(NCI)

C85711 mg/mL/h g/L/h; ug/uL/h; Milligrams per milliliter per hour. Milligram per Milliliter per Hour mg/h/mL; g/h/L; ug/h/uL

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 339 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C85494 - PKUNIT - PK Parameter Units of Measure Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C73742 mg/min Milligrams per minute. Milligram per Minute

C85712 mg/s mg/sec; mg/s Milligrams per second. Milligram per Second

C85724 min*fg/mL pg*min/L; Minutes times femtograms per milliliter. Minute Times Femtogram per min*pg/L; Milliliter fg*min/mL; min*fg/mL

C85725 min*g/mL g*min/mL; Minutes times grams per milliliter. Minute Times Gram per Milliliter min*kg/L; kg*min/L; min*g/mL

C85726 min*kg/mL kg*min/mL; Minutes times kilograms per milliliter. Minute Times Kilogram per g*min/uL; Milliliter min*g/uL; min*kg/mL

C85729 min*mg/mL mg*min/mL; Minutes times milligrams per milliliter. Minute Times Milligram per min*g/L; Milliliter g*min/L; ug*min/uL; min*ug/uL; min*mg/mL

C85730 min*mmol/mL mmol*min/mL; Minutes times millimoles per milliliter. Minute Times Millimole per min*mol/L; Milliliter mol*min/L; min*umol/uL; umol*min/uL; min*mmol/mL

C85731 min*mol/mL mol*min/mL; Minutes times moles per milliliter. Minute Times Mole per Milliliter min*mol/mL

C85732 min*ng/mL ng*min/mL; Minutes times nanograms per milliliter. Minute Times Nanogram per min*ug/L; Milliliter ug*min/L; min*ng/mL

C85733 min*nmol/mL nmol*min/mL; Minutes times nanomoles per milliliter. Minute Times Nanomole per min*umol/L; Milliliter umol*min/L; min*nmol/mL

C85734 min*pg/mL pg*min/mL; Minutes times picograms per milliliter. Minute Times Picogram per min*ng/L; Milliliter ng*min/L; min*pg/mL

C85735 min*pmol/mL nmol*min/L; Minutes times picomoles per milliliter. Minute Times Picomole per min*nmol/L; Milliliter pmol*min/mL; min*pmol/mL

C85727 min*ug/mL ug*min/mL; Minutes times micrograms per milliliter. Minute Times Microgram per min*mg/L; Milliliter mg*min/L; min*mcg/mL; mcg*min/mL

C85728 min*umol/mL umol*min/mL; Minutes times micromoles per milliliter. Minute Times Micromole per min*mcmol/mL; Milliliter min*mmol/L; mmol*min/L; min*umol/mL

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 340 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C85494 - PKUNIT - PK Parameter Units of Measure Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C85720 mmol/h Millimoles per hour. Millimole per Hour

C48555 mmol/mL Mole per Liter; A unit of concentration (molarity unit) equal to one Mole per Liter mol/L; mmol/mL mole of solute in one liter of solution.(NCI)

C85721 mmol/mL/h mol/L/h; Millimoles per milliliter per hour. Millimole per Milliliter per Hour umol/uL/h; mmol/h/mL; mol/h/L; umol/h/uL; mmol/mL/h

C85722 mmol/min Millimoles per minute. Millimole per Minute

C85723 mmol/s mmol/sec; Millimoles per second. Millimole per Second mmol/s

C85737 mol/day mol/d Moles per day. Mole per Day

C85738 mol/h Moles per hour. Mole per Hour

C85739 mol/min Moles per minute. Mole per Minute

C85740 mol/s mol/sec; mol/s Moles per second. Mole per Second

C69188 nL Nanoliter A unit of volume equal to one billionth of a liter Nanoliter (10E-9 liter).(NCI)

C85760 nU/mL uU/L; mcU/L; Nanounits per milliliter. Nanounit per Milliliter nU/mL

C48516 ng Nanogram A unit of mass equal to one billionth (10E-9) of a Nanogram gram, or one millionth (10E-6) of a milligram.(NCI)

C85741 ng/day ng/d Nanograms per day. Nanogram per Day

C85742 ng/h Nanograms per hour. Nanogram per Hour

C85743 ng/kg/min ng/min/kg; Nanograms per kilogram per minute. Nanogram per Kilogram per Minute pg/g/min; pg/min/g; ng/kg/min

C67306 ng/mL mg/m3; A unit of mass concentration defined as the Microgram per Liter Microgram per concentration of one microgram of a substance per Liter; Milligram unit volume of the mixture equal to one liter. The per Cubic Meter; concept also refers to the unit of mass density Nanogram per (volumic mass) defined as the density of substance Milliliter; ug/L; which mass equal to one microgram occupies the ng/mL; mcg/L volume one liter.(NCI)

C85748 ng/mL*kg ng/kg*mL; Nanograms per milliliter times kilogram. Nanogram per Milliliter Times ng/mL*kg Kilogram

C67430 ng/mL/h ug/L/h; ng/h/mL; Nanograms per milliliter per hour. Nanogram per Milliliter per Hour ng/mL/h

C85746 ng/mL/kg ng/kg/mL; Nanograms per milliliter per kilogram. Nanogram per Milliliter per ng/mL/kg Kilogram

C85747 ng/mL/mg ng/mg/mL; Nanograms per milliliter per milligram. Nanogram per Milliliter per ng/mL/mg Milligram

C85744 ng/mg of Creatinine ug/g of Nanograms per milligram of creatinine. Nanogram per Milligram of Creatinine; Creatinine ng/mg of Creatinine

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 341 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C85494 - PKUNIT - PK Parameter Units of Measure Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C85749 ng/min Nanograms per minute. Nanogram per Minute

C85750 ng/s ng/sec; ng/s Nanograms per second. Nanogram per Second

C85755 nmol/L/umol nmol/L/mcmol; Nanomoles per liter per micromole. Nanomole per Liter per Micromole nmol/umol/L; nmol/mcmol/L; nmol/L/umol

C85751 nmol/day nmol/d Nanomoles per day. Nanomole per Day

C85752 nmol/g umol/kg; Nanomoles per gram. Nanomole per Gram pmol/mg; nmol/g

C85753 nmol/h Nanomoles per hour. Nanomole per Hour

C85754 nmol/kg pmol/g; nmol/kg Nanomoles per kilogram. Nanomole per Kilogram

C85756 nmol/mL umol/L; Nanomoles per milliliter. Nanomole per Milliliter mcmol/L; nmol/mL

C85757 nmol/mL/h umol/L/h; Nanomoles per milliliter per hour. Nanomole per Milliliter per Hour nmol/h/mL; nmol/mL/h

C85758 nmol/min Nanomoles per minute. Nanomole per Minute

C85759 nmol/s nmol/sec; nmol/s Nanomoles per second. Nanomole per Second

C67331 pg/dL Picograms per deciliter. Picogram per Deciliter

C85778 pg/day pg/d Picograms per day. Picogram per Day

C85779 pg/h Picograms per hour. Picogram per Hour

C67327 pg/mL ug/m3; A unit of mass concentration defined as the Nanogram per Liter Microgram per concentration of one nanogram of a substance per one Cubic Meter; liter of the mixture, or one picogram of a substance in ng/L; pg/mL unit volume of the mixture equal to one milliliter, or one microgram of a substance per one cubic meter of the mixture. The concept also refers to the metric unit of mass density (volumic mass) defined as the density of substance which mass equal to one nanogram occupies the volume one liter.(NCI)

C85781 pg/mL/ug pg/mL/mcg; Picograms per milliliter per microgram. Picogram per Milliliter per pg/ug/mL; Microgram pg/mcg/mL

C67396 pg/mg mcg/kg; A unit of a mass fraction expressed as a number of Microgram per Kilogram Microgram per micrograms of substance per kilogram of mixture. The Kilogram; ng/g; unit is also used as a dose calculation unit.(NCI) ug/kg

C85780 pg/mg Creatinine ng/g of Picograms per milligram creatinine. Picogram per Milligram of Creatinine; Creatinine pg/mg of Creatinine

C85782 pg/min Picograms per minute. Picogram per Minute

C85783 pg/s pg/sec; pg/s Picograms per second. Picogram per Second

C85784 pmol/L/ug pmol/L/mcg; Picomoles per liters per microgram. Picomole per Liter per Microgram pmol/ug/L; pmol/mcg/L

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 342 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C85494 - PKUNIT - PK Parameter Units of Measure Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C85802 s*fg/mL pg*s/L; Seconds times femtograms per milliliter. Second Times Femtogram per sec*fg/mL; Milliliter s*pg/L; fg*s/mL; fg*sec/mL; s*fg/mL

C85803 s*g/mL g*s/mL; Seconds times grams per milliliter. Second Times Gram per Milliliter sec*g/mL; g*sec/mL; s*kg/L; kg*s/L; sec*kg/L; kg*sec/L

C85804 s*kg/mL kg*s/mL; g*s/uL; Seconds times kilograms per milliliter. Second Times Kilogram per s*g/uL; Milliliter kg*sec/mL; g*sec/uL; sec*g/uL; s*kg/mL

C85807 s*mg/mL mg*s/mL; Seconds times milligrams per milliliter. Second Times Milligram per sec*mg/mL; Milliliter s*g/L; g*s/L; s*mg/mL

C85808 s*mmol/mL mmol*s/mL; Seconds times millimoles per milliliter. Second Times Millimole per sec*mmol/mL; Milliliter s*mol/L; mol*s/L; sec*mol/L; mol*sec/L; s*mmol/mL

C85809 s*mol/mL mol*s/mL; Seconds times moles per milliliter. Second Times Mole per Milliliter sec*mol/mL; mol*sec/mL; s*mol/mL

C85810 s*ng/mL ng*s/mL; Seconds times nanograms per milliliter. Second Times Nanogram per sec*ng/mL; Milliliter ng*sec/mL; s*ug/L; ug*s/L; sec*ug/L; ug*sec/L; s*ng/mL

C85811 s*nmol/mL nmol*s/mL; Seconds times nanomoles per milliliter. Second Times Nanomole per sec*nmol/mL; Milliliter nmol*sec/mL; s*umol/L; umol*s/L; sec*umol/L; umol*sec/L; s*nmol/mL

C85812 s*pg/mL pg*s/mL; Seconds times picograms per milliliter. Second Times Picogram per sec*pg/mL; Milliliter pg*sec/mL; s*ng/L; ng*s/L; sec*ng/L; ng*sec/L; s*pg/mL

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 343 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C85494 - PKUNIT - PK Parameter Units of Measure Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C85813 s*pmol/mL nmol*s/L; Seconds times picomoles per milliliter. Second Times Picomole per s*nmol/L; Milliliter sec*pmol/mL; pmol*s/mL; pmol*sec/mL; s*pmol/mL

C85805 s*ug/mL ug*s/mL; Seconds times micrograms per milliliter. Second Times Microgram per s*mcg/mL; Milliliter ug*sec/mL; sec*ug/mL; sec*mcg/mL; mcg*sec/mL; s*mg/L; mg*s/L

C85806 s*umol/mL umol*s/mL; Seconds times micromoles per milliliter. Second Times Micromole per s*mcmol/mL; Milliliter sec*umol/mL; umol*sec/mL; mcmol*sec/mL; sec*mcmol/mL; s*mmol/L; mmol*s/L; s*umol/mL

C67405 uIU/mL Micro-Internatio Microinternational units per milliliter. Microinternational Unit per nal Unit per Milliliter milliliter; mIU/L; mcIU/mL; uIU/mL

C48153 uL mcL; Microliter; A unit of volume accepted for use with the SI and equal Microliter mm3 to one millionth of a liter (10E-6 liter).(NCI)

C48152 ug Microgram; mcg A unit of mass equal to one millionth of a gram or one Microgram thousandth of a milligram.(NCI)

C71205 ug/day Microgram per A unit of mass flow rate equivalent to the rate at which Microgram per Day Day; mcg/day one millionth of a gram of matter travels to a given object or space over a period of time equal to twenty four hours. Microgram per day is also a dose administration rate unit equal to the rate at which one millionth of a gram of a product is administered per unit of time equal to twenty four hours.(NCI)

C67394 ug/h Micrograms per A unit of mass flow rate equivalent to the rate at which Microgram per Hour Hour; mcg/h one millionth of a gram of matter travels to a given object or space over a period of time equal to one hour.(NCI)

C85703 ug/inh mcg/inh Micrograms per inhalation. Microgram per Inhalation

C64572 ug/mL g/m3; Gram per A unit of mass concentration equal to the Microgram per Milliliter Cubic Meter; concentration of one gram of a substance per unit mg/L; volume of the mixture equal to one cubic meter. The Microgram per concept also refers to the metric unit of mass density Milliliter; (volumic mass) defined as the density of substance Milligram per which mass equal to one gram occupies the volume Liter; mcg/mL; one cubic meter.(NCI) ng/uL; ug/mL

C71211 ug/min Micrograms per A unit of mass flow rate equivalent to the rate at which Microgram per Minute Minute; mcg/min one millionth of a gram of matter travels to a given object or space over a period of time equal to one minute. Microgram per minute is also a dose administration rate unit equal to the rate at which one millionth of a gram of a product is administered per unit of time equal to one minute.(NCI)

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 344 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C85494 - PKUNIT - PK Parameter Units of Measure Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C85704 ug/puff mcg/puff Micrograms per puff. Microgram per Puff

C85705 ug/s mcg/sec; mcg/s; Micrograms per second. Microgram per Second ug/sec; ug/s

C67406 umol/day Micromoles per A unit of amount of substance flow rate equivalent to Micromole per 24 Hours Day; mcmol/day the rate at which one millionth of a mole of substance travels to a given object or space over a period of time equal to 24 hours.(NCI)

C85707 umol/h mcmol/h; umol/h Micromoles per hour. Micromole per Hour

C64387 umol/mL Millimole per A unit of concentration (molarity unit) equal to one Millimole per Liter Liter; umol/mL; thousandth of a mole (10E-3 mole) of solute per one Micromole per liter of solution.(NCI) Milliliter; mol/m3; Mole per Cubic Meter; mcmol/mL; mmol/L; nmol/uL

C85708 umol/min mcmol/min; Micromoles per minute. Micromole per Minute umol/min

C85709 umol/s umol/sec; Micromoles per second. Micromole per Second mcmol/s; mcmol/sec; umol/s

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 345 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C99075 - PORTOT - Portion/Totality Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C64916 ALL Being or representing the total number of individual All entities.

C25326 ENTIRE Whole Being or representing the complete extent of a single Whole entity.

C17648 MULTIPLE Many; Several More than one. (NCI) Many

C25378 PARTIAL Being or representing an incomplete extent of a single Partial entity.

C45312 SEGMENT One of the parts into which something is divided. Segment

C48440 SINGLE One. Single

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 346 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C71148 - POSITION - Position Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C62173 FOWLERS Fowlers A semi-sitting position whereby the head of an Fowler's Position adjustable bed is elevated to the desired height, about 60-90 cm, to produce angulation of the body, usually 45 degrees to 60 degrees. Knees may or may not be bent. (NCI)

C100758 LATERAL DECUBITUS Lateral Lying down on one side. Lateral Decubitus Position Decubitus

C62172 LEFT LATERAL DECUBITUS Left lateral A recumbent left lateral side position. (NCI) Left Lateral Decubitus Position decubitus

C62165 PRONE Prone An anterior recumbent body position whereby the Prone Position person lies on its stomach and faces downward. (NCI)

C62169 REVERSE Reverse A supine position with the person inclined at an angle Reverse Trendelenburg TRENDELENBURG Trendelenburg of 45 degrees so that the head is higher than the pelvis. (NCI)

C62171 RIGHT LATERAL Right lateral A recumbent right lateral side position. (NCI) Right Lateral Decubitus Position DECUBITUS decubitus

C62174 SEMI-FOWLERS Semi-Fowlers A semi-sitting or semi-reclined body position whereby Semi-Fowler's Position the head is elevated on an angle of approximately 30 degrees. (NCI)

C62122 SITTING Sitting The state or act of one who sits; the posture of one Sitting who occupies a seat. (NCI)

C92604 SLING Sling A position in which the subject's body is supported by Patient in Body Sling a sling.

C62166 STANDING Standing The act of assuming or maintaining an erect upright Standing position. (NCI)

C62167 SUPINE Supine A posterior recumbent body position whereby the Supine Position person lies on its back and faces upward. (NCI)

C62168 TRENDELENBURG Trendelenburg A supine position with the person inclined at an angle Trendelenburg of 45 degrees so that the pelvis is higher than the head. (NCI)

C90480 UNCONSTRAINED Unconstrained The ability to move body parts and limbs without Unconstrained Body Movement physical restriction. (NCI)

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 347 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C74457 - RACE - Race Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C41259 AMERICAN INDIAN OR A person having origins in any of the original peoples American Indian or Alaska Native ALASKA NATIVE of North and South America (including Central America), and who maintains tribal affiliation or community attachment. (FDA)

C41260 ASIAN A person having origins in any of the original peoples Asian of the Far East, Southeast Asia, or the Indian subcontinent including, for example, Cambodia, China, India, Japan, Korea, Malaysia, Pakistan, the Philippine Islands, Thailand, and Vietnam. (FDA)

C16352 BLACK OR AFRICAN A person having origins in any of the black racial African American AMERICAN groups of Africa. Terms such as "Haitian" or "Negro" can be used in addition to "Black or African American." (FDA)

C41219 NATIVE HAWAIIAN OR Denotes a person having origins in any of the original Native Hawaiian or Other Pacific OTHER PACIFIC ISLANDER peoples of Hawaii, Guam, Samoa, or other Pacific Islander Islands. The term covers particularly people who identify themselves as part-Hawaiian, Native Hawaiian, Guamanian or Chamorro, Carolinian, Samoan, Chuu. (FDA)

C41261 WHITE Denotes a person with European, Middle Eastern, or White North African ancestral origin who identifies, or is identified, as White. (FDA)

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 348 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C100130 - RELSUB - Relationship to Subject Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C96569 AUNT, BIOLOGICAL Biological Aunt A female relative who is a sibling of either of the Biological Aunt biological parents, and who share a common ancestor. (NCI)

C96575 AUNT, BIOLOGICAL Biological A female relative who is a sibling of the biological Biological Maternal Aunt MATERNAL Maternal Aunt mother, and who both share a common ancestor. (NCI)

C96581 AUNT, BIOLOGICAL Biological A female relative who is a sibling of the biological Biological Paternal Aunt PATERNAL Paternal Aunt father, and who both share a common ancestor. (NCI)

C96570 BROTHER, BIOLOGICAL Biological A male who shares with his sibling the genetic makeup Biological Brother Brother inherited from one or both of their shared biological parents.

C96656 BROTHER, BIOLOGICAL Half-brother with A male who shares with his sibling the genetic makeup Half-brother with Mother as MATERNAL HALF Mother as inherited from only the biological mother. Common Parent Common Parent

C96655 BROTHER, BIOLOGICAL Half-brother with A male who shares with his sibling the genetic makeup Half-brother with Father as Common PATERNAL HALF Father as inherited from only the biological father. Parent Common Parent

C71402 BROTHER, HALF Half Brother A male who shares with his sibling the genetic makeup Half Brother inherited from only one of the biological parents.

C17445 CAREGIVER Caregiver The primary person in charge of the care of a patient, Caregiver usually a family member or a designated health care professional. (NCI)

C100807 CHILD, BIOLOGICAL Biological Child A son or daughter with genetic makeup inherited from Biological Child the parent.

C85499 CLINICIAN Clinician An individual, such as a physician, nurse practitioner or Clinician other health care professional, who takes responsibility for a subject's care.

C96571 COUSIN, BIOLOGICAL Biological A relative who is the offspring of a sibling of either of Biological Cousin Cousin the biological parents, and who share a common ancestor. (NCI)

C96576 COUSIN, BIOLOGICAL Biological A relative who is the offspring of a sibling of the Biological Maternal Cousin MATERNAL Maternal Cousin biological mother and share a common ancestor.

C96582 COUSIN, BIOLOGICAL Biological A relative who is the offspring of a sibling of the Biological Paternal Cousin PATERNAL Paternal Cousin biological father and share a common ancestor.

C53262 DOMESTIC PARTNER Domestic Person declares that a domestic partnership Domestic Partnership Partner relationship exists. (HL7)

C48284 DONOR Donor One that contributes something. (NCI) Donor

C100810 DONOR, ORGAN Organ Donor Someone from whom an organ is removed for Organ Donor transplantation or other purpose.

C25168 DONOR, TISSUE Tissue Donor Someone from whom tissue is removed for Tissue Donor transplantation or other purpose.

C41256 FAMILY MEMBER Family Member Any of the individuals who are descended from a Family Member common progenitor, related by marriage or other legal tie.

C96572 FATHER, BIOLOGICAL Biological Father A male who contributes to the genetic makeup of his Biological Father offspring through the fertilization of an ovum by his sperm. (NCI)

C100805 GRANDCHILD, Biological A biological child of an individual's biological child. Biological Grandchild BIOLOGICAL Grandchild

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 349 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C100130 - RELSUB - Relationship to Subject Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C96573 GRANDFATHER, Biological A male relative who is the biological father of either Biological Grandfather BIOLOGICAL Grandfather the biological mother or the biological father. (NCI)

C96577 GRANDFATHER, Biological A male relative who is the biological father of the Biological Maternal Grandfather BIOLOGICAL MATERNAL Maternal biological mother. (NCI) Grandfather

C96583 GRANDFATHER, Biological A male relative who is the biological father of the Biological Paternal Grandfather BIOLOGICAL PATERNAL Paternal biological father. (NCI) Grandfather

C96574 GRANDMOTHER, Biological A female relative who is the biological mother of Biological Grandmother BIOLOGICAL Grandmother either the biological mother or the biological father. (NCI)

C96578 GRANDMOTHER, Biological A female relative who is the biological mother of the Biological Maternal Grandmother BIOLOGICAL MATERNAL Maternal biological mother. (NCI) Grandmother

C96584 GRANDMOTHER, Biological A female relative who is the biological mother of the Biological Paternal Grandmother BIOLOGICAL PATERNAL Paternal biological father. (NCI) Grandmother

C100806 GRANDPARENT, Biological A biological parent of the biological father or Biological Grandparent BIOLOGICAL Grandparent biological mother.

C96580 MOTHER, BIOLOGICAL Biological A female who contributes to the genetic makeup of her Biological Mother Mother offspring from the fertilization of her ovum. (NCI)

C20821 NURSE Nurse A professional healthcare provider who has graduated Nurse from a nursing program.

C100811 PREGNANCY PARTNER Pregnancy An individual who provides support to a pregnant Pregnancy Partner Partner individual.

C21481 RELATIVE, FIRST DEGREE First Degree Any individual related biologically or legally to First Degree Relative Relative another individual and considered immediate family as in the case of a spouse, parent, sibling or child.

C19811 RELATIVE, SECOND Second Degree Any individual related biologically or legally to Second Degree Relative DEGREE Relative another individual and considered one degree removed from the immediate family as in the case of in-laws, grandparents, aunts and uncles.

C100808 RELATIVE, THIRD DEGREE Third Degree Any individual related biologically or legally to Third Degree Relative Relative another individual and considered two degrees removed from the immediate family as in the case of cousins.

C100812 SEXUAL PARTNER Sexual Partner A person with whom one has had sexual relations. Sexual Partner

C100809 SIBLING, BIOLOGICAL Biological A person's brother or sister with whom they share a Biological Sibling Sibling genetic makeup inherited from their shared biological parents.

C96586 SISTER, BIOLOGICAL Biological Sister A female who shares with her sibling the genetic Biological Sister makeup inherited from one or both of their shared biological parents.

C96658 SISTER, BIOLOGICAL Half-sister with A female who shares with her sibling the genetic Half-sister with Mother as Common MATERNAL HALF Mother as makeup inherited from only the biological mother. Parent Common Parent

C96657 SISTER, BIOLOGICAL Half-sister with A female who shares with her sibling the genetic Half-sister with Father as Common PATERNAL HALF Father as makeup inherited from only the biological father. Parent Common Parent

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 350 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C100130 - RELSUB - Relationship to Subject Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C71403 SISTER, HALF Half Sister A female who shares with her sibling the genetic Half Sister makeup inherited from only one of the biological parents.

C62649 SPOUSE Spouse A person's partner in marriage. (NCI) Spouse

C63861 TECHNICIAN Technician A person skilled in the performance of the technical or Technician procedural aspects of a profession. (NCI)

C73427 TWIN Twin Either of two offspring born from the same pregnancy. Twin (NCI)

C73428 TWIN, DIZYGOTIC Dizygotic Twin Either of the two offspring resulting from two Fraternal Twin separately fertilized ovums during the same pregnancy.

C73429 TWIN, MONOZYGOTIC Monozygotic Either of the two offspring resulting from a shared Identical Twin Twin ovum. (NCI)

C96587 UNCLE, BIOLOGICAL Biological Uncle A male relative who is a sibling of either of the Biological Uncle biological parents, and who share a common ancestor. (NCI)

C96579 UNCLE, BIOLOGICAL Biological A male relative who is a sibling of the biological Biological Maternal Uncle MATERNAL Maternal Uncle mother, and who both share a common ancestor. (NCI)

C96585 UNCLE, BIOLOGICAL Biological A male relative who is a sibling of the biological Biological Paternal Uncle PATERNAL Paternal Uncle father, and who both share a common ancestor. (NCI)

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 351 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C78737 - RELTYPE - Relationship Type Codelist extensible: No

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C78728 MANY Many; Several More than one. (NCI) Many

C66832 ONE A textual representation of the numeral 1. One

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 352 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C66729 - ROUTE - Route of Administration Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C38192 AURICULAR (OTIC) Administration to or by way of the ear. (FDA) Auricular Route of Administration

C38193 BUCCAL Administration directed toward the cheek, generally Buccal Route of Administration from within the mouth. (FDA)

C38194 CONJUNCTIVAL Administration to the conjunctiva, the delicate Conjunctival Route of membrane that lines the eyelids and covers the Administration exposed surface of the eyeball. (FDA)

C38675 CUTANEOUS Administration to the skin. (FDA) Cutaneous Route of Administration

C38197 DENTAL Administration to a tooth or teeth. (FDA) Dental Route of Administration

C78373 DIETARY Administration by way of food stuff. (NCI) Dietary Route of Administration

C38633 ELECTRO-OSMOSIS Administration of through the diffusion of substance Electro-osmosis Route of through a membrane in an electric field. (FDA) Administration

C38205 ENDOCERVICAL Administration within the canal of the cervix uteri. Endocervical Route of Synonymous with the term intracervical. (FDA) Administration

C38206 ENDOSINUSIAL Administration within the nasal sinuses of the head. Endosinusial Route of (FDA) Administration

C38208 ENDOTRACHEAL Administration directly into the trachea. Synonymous Endotracheal Route of with the term intratracheal. (FDA) Administration

C38209 ENTERAL Administration directly into the intestines. (FDA) Enteral Route of Administration

C38210 EPIDURAL Administration upon or over the dura mater. (FDA) Epidural Route of Administration

C38211 EXTRA-AMNIOTIC Administration to the outside of the membrane Extraamniotic Route of enveloping the fetus. (FDA) Administration

C38212 EXTRACORPOREAL Administration outside of the body. (FDA) Extracorporeal Circulation Route of Administration

C38200 HEMODIALYSIS Administration through hemodialysate fluid. (FDA) Administration Via Hemodialysis

C38215 INFILTRATION Administration that results in substances passing into Infiltration Route of Administration tissue spaces or into cells. (FDA)

C38219 INTERSTITIAL Administration to or in the interstices of a tissue. Interstitial Route of Administration (FDA)

C38220 INTRA-ABDOMINAL Administration within the abdomen. (FDA) Intraabdominal Route of Administration

C38221 INTRA-AMNIOTIC Administration within the amnion. (FDA) Intraamniotic Route of Administration

C38222 INTRA-ARTERIAL Administration within an artery or arteries. (FDA) Intraarterial Route of Administration

C38223 INTRA-ARTICULAR Administration within a joint. (FDA) Intraarticular Route of Administration

C38224 INTRABILIARY Administration within the bile, bile ducts or Intrabiliary Route of Administration gallbladder. (FDA)

C38225 INTRABRONCHIAL Administration within a bronchus. (FDA) Intrabronchial Route of Administration

C38226 INTRABURSAL Administration within a bursa. (FDA) Intrabursal Route of Administration

C38227 INTRACARDIAC Administration within the heart. (FDA) Intracardiac Route of Administration

C38228 INTRACARTILAGINOUS Administration within a cartilage; endochondral. (FDA) Intracartilaginous Route of Administration

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 353 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C66729 - ROUTE - Route of Administration Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C38229 INTRACAUDAL Administration within the cauda equina. (FDA) Intracaudal Route of Administration

C38230 INTRACAVERNOUS Administration within a pathologic cavity, such as Intracavernous Route of occurs in the lung in tuberculosis. (FDA) Administration

C38231 INTRACAVITARY Administration within a non-pathologic cavity, such as Intracavitary Route of Administration that of the cervix, uterus, or penis, or such as that is formed as the result of a wound. (FDA)

C38232 INTRACEREBRAL Administration within the cerebrum. (FDA) Intracerebral Route of Administration

C38233 INTRACISTERNAL Administration within the cisterna magna Intracisternal Route of cerebellomedularis. (FDA) Administration

C38234 INTRACORNEAL Administration within the cornea (the transparent Intracorneal Route of Administration structure forming the anterior part of the fibrous tunic of the eye). (FDA)

C38217 INTRACORONAL, DENTAL Administration of a drug within a portion of a tooth Intracoronal Dental Route of which is covered by enamel and which is separated Administration from the roots by a slightly constricted region known as the neck. (FDA)

C38218 INTRACORONARY Administration within the coronary arteries. (FDA) Intracoronary Route of Administration

C38235 INTRACORPORUS Administration within the dilatable spaces of the Intracorporus Cavernosum Route of CAVERNOSUM corporus cavernosa of the penis. (FDA) Administration

C38238 INTRADERMAL Administration within the dermis. (FDA) Intradermal Route of Administration

C38239 INTRADISCAL Administration within a disc. (FDA) Intradiscal Route of Administration

C38240 INTRADUCTAL Administration within the duct of a gland. (FDA) Intraductal Route of Administration

C38241 INTRADUODENAL Administration within the duodenum. (FDA) Intraduodenal Route of Administration

C38242 INTRADURAL Administration within or beneath the dura. (FDA) Intradural Route of Administration

C38243 INTRAEPIDERMAL Administration within the epidermis. (FDA) Intraepidermal Route of Administration

C38245 INTRAESOPHAGEAL Administration within the esophagus. (FDA) Intraesophageal Route of Administration

C38246 INTRAGASTRIC Administration within the stomach. (FDA) Intragastric Route of Administration

C38247 INTRAGINGIVAL Administration within the gingivae. (FDA) Intragingival Route of Administration

C38249 INTRAILEAL Administration within the distal portion of the small Intraileal Route of Administration intestine, from the jejunum to the cecum. (FDA)

C38250 INTRALESIONAL Administration within or introduced directly into a Intralesional Route of localized lesion. (FDA) Administration

C38251 INTRALUMINAL Administration within the lumen of a tube. (FDA) Intraluminal Route of Administration

C38252 INTRALYMPHATIC Administration within the lymph. (FDA) Intralymphatic Route of Administration

C38253 INTRAMEDULLARY Administration within the marrow cavity of a bone. Intramedullary Route of (FDA) Administration

C38254 INTRAMENINGEAL Administration within the meninges (the three Intrameningeal Route of membranes that envelope the brain and spinal cord). Administration (FDA)

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 354 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C66729 - ROUTE - Route of Administration Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C28161 INTRAMUSCULAR Administration within a muscle. (FDA) Intramuscular Route of Administration

C38255 INTRAOCULAR Administration within the eye. (FDA) Intraocular Route of Administration

C38256 INTRAOVARIAN Administration within the ovary. (FDA) Intraovarian Route of Administration

C38257 INTRAPERICARDIAL Administration within the pericardium. (FDA) Intrapericardial Route of Administration

C38258 INTRAPERITONEAL Administration within the peritoneal cavity. (FDA) Intraperitoneal Route of Administration

C38259 INTRAPLEURAL Administration within the pleura. (FDA) Intrapleural Route of Administration

C38260 INTRAPROSTATIC Administration within the prostate gland. (FDA) Intraprostatic Route of Administration

C38261 INTRAPULMONARY Administration within the lungs or its bronchi. (FDA) Intrapulmonary Route of Administration

C38262 INTRASINAL Administration within the nasal or periorbital sinuses. Intrasinal Route of Administration (FDA)

C38263 INTRASPINAL Administration within the vertebral column. (FDA) Intraspinal Route of Administration

C38264 INTRASYNOVIAL Administration within the synovial cavity of a joint. Intrasynovial Route of (FDA) Administration

C38265 INTRATENDINOUS Administration within a tendon. (FDA) Intratendinous Route of Administration

C38266 INTRATESTICULAR Administration within the testicle. (FDA) Intratesticular Route of Administration

C38267 INTRATHECAL Administration within the cerebrospinal fluid at any Intrathecal Route of Administration level of the cerebrospinal axis, including injection into the cerebral ventricles. (FDA)

C38207 INTRATHORACIC Administration within the thorax (internal to the ribs); Endothoracic Route of synonymous with the term endothoracic. (FDA) Administration

C38268 INTRATUBULAR Administration within the tubules of an organ. (FDA) Intratubular Route of Administration

C38269 INTRATUMOR Intratumor Route Administration within a tumor. (FDA) Intratumoral Route of Administration of Administration

C38270 INTRATYMPANIC Administration within the auris media. (FDA) Intratympanic Route of Administration

C38272 INTRAUTERINE Administration within the uterus. (FDA) Intrauterine Route of Administration

C38273 INTRAVASCULAR Administration within a vessel or vessels. (FDA) Intravascular Route of Administration

C38276 INTRAVENOUS Administration within or into a vein or veins. (FDA) Intravenous Route of Administration

C38274 INTRAVENOUS BOLUS Administration within or into a vein or veins all at Intravenous Bolus once. (FDA)

C38279 INTRAVENOUS DRIP Administration within or into a vein or veins over a Intravenous Drip sustained period of time. (FDA)

C38277 INTRAVENTRICULAR Administration within a ventricle. (FDA) Intraventricular Route of Administration

C38278 INTRAVESICAL Administration within the bladder. (FDA) Intravesical Route of Administration

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 355 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C66729 - ROUTE - Route of Administration Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C38280 INTRAVITREAL Administration within the vitreous body of the eye. Intravitreal Route of Administration (FDA)

C38203 IONTOPHORESIS Administration by means of an electric current where Iontophoresis Route of ions of soluble salts migrate into the tissues of the Administration body. (FDA)

C38281 IRRIGATION Administration to bathe or flush open wounds or body Irrigation-Route of Administration cavities. (FDA)

C38282 LARYNGEAL Administration directly upon the larynx. (FDA) Laryngeal Route of Administration

C38284 NASAL Administration to the nose; administered by way of the Nasal Route of Administration nose. (FDA)

C38285 NASOGASTRIC Administration through the nose and into the stomach, Nasogastric Route of Administration usually by means of a tube. (FDA)

C48623 NOT APPLICABLE Routes of administration are not applicable. (FDA) Route of Administration Not Applicable

C38286 OCCLUSIVE DRESSING Administration by the topical route which is then Occlusive Dressing Technique TECHNIQUE covered by a dressing which occludes the area. (FDA)

C38287 OPHTHALMIC Administration to the external eye. (FDA) Ophthalmic Route of Administration

C38288 ORAL PO Administration to or by way of the mouth. (FDA) Oral Route of Administration

C78374 ORAL GAVAGE Administration through the mouth and into the Oral Gavage Route of Administration stomach, usually by means of a tube. (NCI)

C38289 OROPHARYNGEAL Administration directly to the mouth and pharynx. Oropharyngeal Route of (FDA) Administration

C38290 OTHER Administration is different from others on this list. Other Route of Administration (FDA)

C38291 PARENTERAL Administration by injection, infusion, or implantation. Parenteral Route of Administration (FDA)

C38676 PERCUTANEOUS Administration through the skin. (FDA) Percutaneous Route of Administration

C38292 PERIARTICULAR Administration around a joint. (FDA) Periarticular Route of Administration

C38677 PERIDURAL Administration to the outside of the dura mater of the Peridural Route of Administration spinal cord. (FDA)

C38293 PERINEURAL Administration surrounding a nerve or nerves. (FDA) Perineural Route of Administration

C38294 PERIODONTAL Administration around a tooth. (FDA) Periodontal Route of Administration

C38295 RECTAL Administration to the rectum. (FDA) Rectal Route of Administration

C38216 RESPIRATORY Administration within the respiratory tract by inhaling Inhalation Route of Administration (INHALATION) orally or nasally for local or systemic effect. (FDA)

C38296 RETROBULBAR Administration behind the pons or behind the eyeball. Retrobulbar Route of Administration (FDA)

C38198 SOFT TISSUE Administration into any soft tissue. (FDA) Soft Tissue Route Of Administration

C38297 SUBARACHNOID Administration beneath the arachnoid. (FDA) Subarachnoid Route of Administration

C38298 SUBCONJUNCTIVAL Administration beneath the conjunctiva. (FDA) Subconjunctival Route of Administration

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 356 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C66729 - ROUTE - Route of Administration Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C38299 SUBCUTANEOUS SC Administration beneath the skin; hypodermic. Subcutaneous Route of Synonymous with the term SUBDERMAL. (FDA) Administration

C38300 SUBLINGUAL Administration beneath the tongue. (FDA) Sublingual Route of Administration

C38301 SUBMUCOSAL Administration beneath the mucous membrane. (FDA) Submucosal Route of Administration

C38304 TOPICAL TOP Administration to a particular spot on the outer surface Topical Route of Administration of the body. The E2B term TRANSMAMMARY is a subset of the term TOPICAL. (FDA)

C38305 TRANSDERMAL Administration through the dermal layer of the skin to Transdermal Route of Administration the systemic circulation by diffusion. (FDA)

C38283 TRANSMUCOSAL Administration across the mucosa. (FDA) Mucosal Route of Administration

C38307 TRANSPLACENTAL Administration through or across the placenta. (FDA) Transplacental Route of Administration

C38308 TRANSTRACHEAL Administration through the wall of the trachea. (FDA) Transtracheal Route of Administration

C38309 TRANSTYMPANIC Administration across or through the tympanic cavity. Transtympanic Route of (FDA) Administration

C38310 UNASSIGNED Route of administration has not yet been assigned. Unassigned Route of Administration (FDA)

C38311 UNKNOWN Route of administration is unknown. (FDA) Unknown Route of Administration

C38312 URETERAL Administration into the ureter. (FDA) Ureteral Route of Administration

C38271 URETHRAL Administration into the urethra. (FDA) Intraurethral Route of Administration

C38313 VAGINAL Administration into the vagina. (FDA) Vaginal Route of Administration

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 357 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C96785 - RSSTRESC - Tumor Response Result Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C4870 CR Complete The disappearance of all signs of cancer in response to Complete Remission Response treatment. (NCI)

C48660 NA Not Applicable Determination of a value is not relevant in the current Not Applicable context. (NCI)

C62222 NE Not Evaluable Unable to be evaluated. (NCI) Unevaluable

C96700 NonCR/NonPD Non Complete Persistence of one or more non-target lesion(s) and/or Non Complete Response/Non Response/Non maintenance of tumor marker levels above the normal Progressive Disease Progressive limits. (RECIST) Disease

C35571 PD Progressive A disease process that is increasing in scope or Progressive Disease Disease severity. (NCI)

C18058 PR Partial Response A finding indicating that there is a decrease in the size Partial Remission and the extent of tissue involvement by a malignant tumor in a patient. (NCI)

C18213 SD Stable Disease Cancer that is neither decreasing nor increasing in Stable Disease extent or severity. (NCI)

C96644 UPD Unequivocal An overall level of substantial worsening in non-target Unequivocal Progression Progression disease that is of a magnitude that, even in the presence of SD or PR in target disease, the treating physician would feel it important to change therapy. (RECIST)

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 358 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C96781 - RSTEST - Tumor Response Assessment Test Name Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C94536 Best Overall Response Best Overall An assessment of the most clinically favorable overall Best Overall Response Response; Best response of the disease to the therapy. Response

C96608 Non-Radiological Progression Non-Radiologica A non-radiological determination of disease Non-Radiological Progression l Progression progression based on symptoms or other findings.

C96609 Non-target Response Non-target An assessment of the response of a non-target Non-target Response Response tumor(s) to the therapy.

C96613 Overall Response Overall An assessment of the overall response of the disease Overall Response Response to the therapy. (NCI)

C96637 Target Response Target Response An assessment of the response of a target tumor(s) to Target Response the therapy.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 359 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C96782 - RSTESTCD - Tumor Response Assessment Test Code Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C94536 BESTRESP Best Overall An assessment of the most clinically favorable overall Best Overall Response Response; Best response of the disease to the therapy. Response

C96608 NRADPROG Non-Radiologica A non-radiological determination of disease Non-Radiological Progression l Progression progression based on symptoms or other findings.

C96609 NTRGRESP Non-target An assessment of the response of a non-target Non-target Response Response tumor(s) to the therapy.

C96613 OVRLRESP Overall An assessment of the overall response of the disease Overall Response Response to the therapy. (NCI)

C96637 TRGRESP Target Response An assessment of the response of a target tumor(s) to Target Response the therapy.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 360 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C74559 - SCCD - Subject Characteristic Code Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C17953 EDLEVEL Education Level Years of education that a person has completed. Education Level

C25193 EMPJOB Employee Job A code specifying the job performed by the employee Occupation for the employer. For example, accountant, programmer analyst, patient care associate, staff nurse, etc.

C74565 JOBCLAS Employee Job A code qualifying the employment in various ways, Employee Job Class Class such as, full-time vs. part time, etc.

C25188 MARISTAT Marital Status A demographic parameter indicating a person's current Marital Status conjugal status.

C74566 SALTYP Employee Salary A code specifying the method used by the employer to Employee Salary Type Type compute the employee's salary or wages. For example, hourly, annual, or commission.

C74563 SKINCLAS Skin A classification system used to categorize the Fitzpatrick Classification Scale Classification sensitivity of a subject's skin to sunlight.

C74580 SKINTYP Skin Type A distinctive characteristic of the skin marked by the Skin Type amount of sebum secreted by sebaceous glands.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 361 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C66731 - SEX - Sex Codelist extensible: No

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C16576 F Female A person who belongs to the sex that normally Female produces ova. The term is used to indicate biological sex distinctions, or cultural gender role distinctions, or both. (NCI)

C20197 M Male A person who belongs to the sex that normally Male produces sperm. The term is used to indicate biological sex distinctions, cultural gender role distinctions, or both. (NCI)

C17998 U U; Unknown Not known, not observed, not recorded, or refused. Unknown (NCI)

C45908 UN Undifferentiated A person (one of unisexual specimens) who is born Intersex with genitalia and/or secondary sexual characteristics of indeterminate sex, or which combine features of both sexes. (NCI)

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 362 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C66732 - SEXPOP - Sex of Participants Codelist extensible: No

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C49636 BOTH One and the other; relating to or being two in Both conjunction. (NCI)

C16576 F Female A person who belongs to the sex that normally Female produces ova. The term is used to indicate biological sex distinctions, or cultural gender role distinctions, or both. (NCI)

C20197 M Male A person who belongs to the sex that normally Male produces sperm. The term is used to indicate biological sex distinctions, cultural gender role distinctions, or both. (NCI)

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 363 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C66733 - SIZE - Size Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C49508 LARGE Of considerable or relatively great size, extent, or Large capacity. (NCI)

C49507 MEDIUM Mid-way between small and large in number, quantity, Medium magnitude or extent. (NCI)

C25376 SMALL Limited in number, quantity, magnitude or extent. Small (NCI)

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 364 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C76351 - SKINCLAS - Skin Classification Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C74569 TYPEI TYPE1 Individuals who never tan and always sunburn if Fitzpatrick Skin Type I exposed to any appreciable amount of sunlight, primarily red headed individuals and lightly complected blondes. (Reference: Fitzpatrick TB: The validity and practicality of sun-reactive skin types I through VI. Arch. Dermatol. 1998 124: 869-871)

C74570 TYPEII TYPE2 Individuals who frequently burn but are able to tan to a Fitzpatrick Skin Type II small degree after extended sun exposure. (Reference: Fitzpatrick TB: The validity and practicality of sun-reactive skin types I through VI. Arch. Dermatol. 1998 124: 869-871)

C74571 TYPEIII TYPE3 Individuals who burn infrequently and tan readily. Fitzpatrick Skin Type III (Reference: Fitzpatrick TB: The validity and practicality of sun-reactive skin types I through VI. Arch. Dermatol. 1998 124: 869-871)

C74572 TYPEIV TYPE4 Individuals who rarely burn and tan heavily with Fitzpatrick Skin Type IV moderate sun exposures, especially individuals of Asian, American Indian, Mediterranean and Latin American descent. (Reference: Fitzpatrick TB: The validity and practicality of sun-reactive skin types I through VI. Arch. Dermatol. 1998 124: 869-871)

C74573 TYPEV TYPE5 Individuals who have dark constitutive pigmentation but Fitzpatrick Skin Type V become noticeably darker with sun exposure, especially light complected black individuals, those of Indian descent. (Reference: Fitzpatrick TB: The validity and practicality of sun-reactive skin types I through VI. Arch. Dermatol. 1998 124: 869-871)

C74574 TYPEVI TYPE6 Individuals who have the heaviest constitutive Fitzpatrick Skin Type VI pigmentation, especially dark skinned black individuals. (Reference: Fitzpatrick TB: The validity and practicality of sun-reactive skin types I through VI. Arch. Dermatol. 1998 124: 869-871)

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 365 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C74561 - SKINTYP - Skin Type Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C74592 DRY The pores are generally fine with a papery thin texture Dry Skin that feels dry to the touch. Usually flaky and dull looking.

C74593 NORMAL The pores are visible but not large. The texture is Normal Skin neither fine or thick and it neither feels dry or oily to the touch.

C74591 OILY The pores of the skin are generally large and visible Oily Skin with a coarse or thick texture. It has a tendency to look dull and greasy and feels oily to the touch.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 366 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C66783 - SOC - CDISC System Organ Class Codelist extensible: No

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C35814 BLOOD AND LYMPHATIC Any deviation from the normal structure or function of Hematopoietic and Lymphoid SYSTEM DISORDERS the blood or lymphatic system that is manifested by a System Disorder characteristic set of symptoms and signs. (NCI)

C3079 CARDIAC DISORDERS Any deviation from the normal structure or function of Heart Disorder the cardiac system that is manifested by a characteristic set of symptoms and signs. (NCI)

C49399 CONGENITAL, FAMILIAL A class of disorders that encompasses conditions Congenital, Familial and Genetic AND GENETIC DISORDERS resulting from a congenital, familial hereditary trait or Disorder Class genetic abnormality as is manifested by a characteristic set of symptoms and signs. (NCI)

C49400 EAR AND LABYRINTH Any deviation from the normal structure or function of Ear and Labyrinth Disorder Class DISORDERS the ear or labyrinth that is manifested by a characteristic set of symptoms and signs. (NCI)

C3009 ENDOCRINE DISORDERS Any deviation from the normal structure or function of Endocrine Disorder the endocrine system that is manifested by a characteristic set of symptoms and signs. (NCI)

C26767 EYE DISORDERS Any deviation from the normal structure or function of Eye Disorder the eye that is manifested by a characteristic set of symptoms and signs. (NCI)

C2990 GASTROINTESTINAL Diseases of the digestive tract (oral cavity to anus) and Gastrointestinal Disorder DISORDERS associated organs (salivary glands, liver, pancreas). (NCI)

C49401 GENERAL DISORDERS A class of disorders that encompasses conditions of a General Disorders and AND ADMINISTRATION general kind that result from a disease, the treatment Administration Site Conditions Class SITE CONDITIONS of disease or administration of treatment at a particular site and are manifested by a characteristic set of symptoms and signs. (NCI)

C3959 HEPATOBILIARY Any deviation from the normal structure or function of Hepatobiliary Disorder DISORDERS the liver or biliary tract that is manifested by a characteristic set of symptoms and signs. (NCI)

C3507 IMMUNE SYSTEM A disorder resulting from an abnormality in the Immune System Disorder DISORDERS immune system. -- 2003 (NCI)

C26726 INFECTIONS AND A disorder resulting from the presence and activity of Infectious Disorder INFESTATIONS a microbial, viral, or parasitic agent. It can be transmitted by direct or indirect contact. -- 2003 (NCI)

C49402 INJURY, POISONING AND A class of disorders that encompasses conditions Injury, Poisoning and Procedural PROCEDURAL resulting from an injury, poisoning or procedure. Complication Class COMPLICATIONS (NCI)

C41198 INVESTIGATIONS The act or process of a systematic and thorough Investigation examination; research, study; the process of inquiring into or following up, intended to develop facts. (NCI)

C49403 METABOLISM AND A class of disorders that encompasses conditions Metabolism and Nutrition Disorder NUTRITION DISORDERS occurring as a result of metabolic dysfunction or Class deviation from the normal nutritional requirements. (NCI)

C27574 MUSCULOSKELETAL AND Any deviation from the normal structure or function of Connective and Soft Tissue Disorder CONNECTIVE TISSUE the musculoskeletal or connective tissue that is DISORDERS manifested by a characteristic set of symptoms and signs. (NCI)

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 367 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C66783 - SOC - CDISC System Organ Class Codelist extensible: No

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C3262 NEOPLASMS BENIGN, An abnormal tissue growth resulted from uncontrolled Neoplasm MALIGNANT AND cell proliferation. Benign neoplastic cells resemble UNSPECIFIED (INCL CYSTS normal cells without exhibiting significant cytologic AND POLYPS) atypia, while malignant ones exhibit overt signs such as dysplastic features, atypical mitotic figures, necrosis, nuclear pleomorphism, and anaplasia. Representative examples of benign neoplasms include papillomas, cystadenomas, and lipomas; malignant neoplasms include carcinomas, sarcomas, lymphomas, and leukemias. -- 2004 (NCI)

C26835 NERVOUS SYSTEM Any deviation from the normal structure or function of Nervous System Disorder DISORDERS the nervous system that is manifested by a characteristic set of symptoms and signs. (NCI)

C49404 PREGNANCY, A class of conditions associated with pregnancy, Pregnancy, Puerperium and Perinatal PUERPERIUM AND puerperium and perinatal status. (NCI) Condition Class PERINATAL CONDITIONS

C2893 PSYCHIATRIC DISORDERS Any deviation from the normal structure or function of Psychiatric Disorder the brain and a psychiatric condition, that results in an impairment of an individual's normal cognitive, emotional, or behavioral functioning, and is caused by physiological or psychosocial factors. (NCI)

C3430 RENAL AND URINARY Disorders of any part of the urologic system. (NCI) Urinary System Disorder DISORDERS

C49405 REPRODUCTIVE SYSTEM Any deviation from the normal structure or function of Reproductive System and Breast AND BREAST DISORDERS the reproductive system or breast that is manifested by Disorder Class a characteristic set of symptoms and signs. (NCI)

C27669 RESPIRATORY, THORACIC Any deviation from the normal structure or function of Respiratory and Thoracic Disorder AND MEDIASTINAL the respiratory system including the thorax and DISORDERS mediastinum that is manifested by a characteristic set of symptoms and signs. (NCI)

C3371 SKIN AND Any deviation from the normal structure or function of Skin Disorder SUBCUTANEOUS TISSUE the skin or subcutaneous tissue that is manifested by a DISORDERS characteristic set of symptoms and signs.(NCI)

C20188 SOCIAL CIRCUMSTANCES A set of concepts that results from or is influenced by Social Circumstances criteria or activities associated with the social environment of a person. (NCI)

C25218 SURGICAL AND MEDICAL A particular course of action intended to achieve a Intervention or Procedure PROCEDURES result. (NCI)

C35117 VASCULAR DISORDERS Any deviation from the normal structure or function of Vascular Disorder the vascular system that is manifested by a characteristic set of symptoms and signs. (NCI)

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 368 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C78733 - SPECCOND - Specimen Condition Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C78725 AUTOLIZED Autolized A specimen that has undergone autolysis, or Autolized Specimen Specimen self-digestion by the specimen's own digestive enzymes. (NCI)

C78723 CALCIFIED Calcified A specimen that has undergone calcification. (NCI) Calcified Specimen Specimen

C78724 CLOTTED Clotted A specimen that has become coagulated. (NCI) Clotted Specimen Specimen

C70717 FROZEN Frozen Specimen A specimen that has been subjected to and Frozen Specimen immobilized by severe cold. (NCI)

C70720 HEMOLIZED Hemolysis in A specimen that has undergone the destruction of red Hemolysis in Specimen Specimen blood cells followed by the release of the hemoglobin. (NCI)

C98744 ICTERIC Icteric Specimen A specimen that exhibits a yellowish pigmentation due Icteric Specimen to jaundice. (NCI)

C70715 LIPEMIC Lipemic A specimen that consists of or contains excessive Lipemic Specimen Specimen amounts of fat and fatty substances. (NCI)

C70718 REFRIGERATED Refrigerated A specimen that has been kept or preserved at a low Refrigerated Specimen Specimen temperature in a refrigerator. (NCI)

C70719 ROOM TEMPERATURE Ambient A specimen that has been subjected to and adjusted to Specimen at Room Temperature Temperature; the average ambient temperature of a room, usually Specimen at considered to be around 20 degrees C (68 degrees F). Room (NCI) Temperature

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 369 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C78734 - SPECTYPE - Specimen Type Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C12472 ADIPOSE TISSUE A specialized form of connective tissue consisting Adipose Tissue primarily of adipocytes (fat cells), surrounded by a meshwork of collagen fibers. (NCI)

C13188 AMNIOTIC FLUID Aqua Amnii The fluid within the amniotic cavity which surrounds Amniotic Fluid and protects the developing embryo. (NCI)

C13190 AQUEOUS HUMOR The watery fluid which is present in the anterior and Aqueous Humor posterior chambers of the eye. (NCI)

C78729 ARTERIAL BLOOD Oxygenated blood which is transported with nutrients Arterial Blood to body tissues through the arterial system. The exception is blood within the pulmonary artery which carries deoxygenated blood to the lungs. (NCI)

C78739 ATHEROSCLEROTIC Fatty tissue which is deposited in the inner lining of Atherosclerotic Plaque PLAQUE the arterial wall. (NCI)

C13192 BILE Fluid composed of waste products, bile acids, salts, Bile cholesterol, and electrolytes. It is secreted by the liver parenchyma and stored in the gallbladder. (NCI)

C12434 BLOOD A liquid tissue with the primary function of Blood transporting oxygen and carbon dioxide. It supplies the tissues with nutrients, removes waste products, and contains various components of the immune system defending the body against infection.

C12366 BONE Calcified connective tissue that forms the skeletal Bone components of the body. (NCI)

C12431 BONE MARROW The tissue occupying the spaces of bone. It consists of Bone Marrow blood vessel sinuses and a network of hematopoietic cells which give rise to the red cells, white cells, and megakaryocytes. (NCI)

C13257 BREAST MILK Milk produced by females for the purpose of feeding Breast Milk their young. (NCI)

C35708 CALCULUS Accumulated material from the secretions of an organ. Stone It is solid and representative examples include gallbladder stones, kidney stones, and salivary gland stones. (NCI)

C12692 CEREBROSPINAL FLUID CSF The fluid that is contained within the brain ventricles, Cerebrospinal Fluid the subarachnoid space and the central canal of the spinal cord. (NCI)

C32293 CERUMEN A wax secreted by glands in the ear canal. Cerumen

C32348 COLOSTRUM A thick, protein-rich substance secreted by the breasts Colostrum during the second half of pregnancy and for a few days after birth before the breast milk comes in.

C77666 EMESIS Emesis; Vomit Stomach contents that have returned to the mouth or Vomitus are ejected beyond the mouth. (NCI)

C78741 EXPIRED AIR The air that moves out of the chest during expiration. It Expired Air contains a higher percentage of carbon dioxide and a lower percentage of oxygen compared to the inhaled air. (NCI)

C13233 EXUDATE Fluid, cells or cellular debris that escapes from the Exudate blood vessels and accumulates in nearby tissues. It is the result of inflammation and is rich in proteins.

C13236 FLUID Liquid substances produced by the body. Body Fluid or Substance

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 370 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C78734 - SPECTYPE - Specimen Type Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C32705 HAIR The filamentous outgrowth of the epidermis. (NCI) Hair

C78742 LOCHIA Vaginal discharge occurring during the post-partum Lochia period. It consists of a mixture of blood, mucus, and placental remnants. (NCI)

C13273 LUNG SURFACTANT Surfactant Pulmonary surfactant lines the lung epithelium and Lung Surfactant lowers surface tension to prevent collapse at end-expiration. Deficiency of pulmonary surfactant results in respiratory distress syndrome (RDS) in premature infants. Lung surfactant is synthesized in alveolar type II cells, stored in lamellar bodies and secreted via exocytosis. (NCI)

C13252 LYMPH A clear, transparent, sometimes faintly yellow and Lymph slightly opalescent fluid that is collected from the tissues throughout the body, flows in the lymphatic vessels (through the lymph nodes), and is eventually added to the venous blood circulation. Lymph consists of a clear liquid portion, varying numbers of white blood cells (chiefly lymphocytes), and a few red blood cells. (NCI)

C78743 MECONIUM The newborn's first intestinal discharge. It is a Meconium dark-green, thick substance composed of mucus, intestinal secretions, hair, and intestinal mucosa cells. (NCI)

C78740 MENSTRUAL BLOOD The discharged blood from the uterus during the Menstrual Blood reproductive years. The discharge occurs approximately once a month. (NCI)

C13259 MUCUS The thick fluid secreted by the mucus glands in the Mucus aerodigestive tract and the vagina. (NCI)

C33156 NAIL The cutaneous plate on the dorsal surface of the distal Nail end of a finger or toe. (NCI)

C13280 PERSPIRATION Sweat The liquid secreted by the sweat glands. (NCI) Sweat

C13356 PLASMA Plasma is the fluid (acellular) portion of the Plasma circulating blood, as distinguished from the serum that is the fluid portion of the blood obtained by removal of the fibrin clot and blood cells after coagulation.

C77613 PLEURAL FLUID The fluid that is abnormally collected in the pleural Pleural Fluid cavity. (NCI)

C100896 PROSTATIC FLUID A slightly alkaline, white fluid secreted from the Prostatic Fluid prostate and is a constituent of semen.

C50718 PUS A yellowish substance produced during bacterial Pus inflammation. It contains necrotic cells and cells fighting the infection. (NCI)

C13275 SALIVA A clear liquid secreted into the mouth by the salivary Saliva glands and mucous glands of the mouth; moistens the mouth and starts the digestion of starches. (NCI)

C13276 SEBUM A thick, oily substance produced by the sebaceous Sebum glands located in the dermis. (NCI)

C13277 SEMEN Seminal Plasma The thick, whitish secretion of the male reproductive Semen organs. It is composed of spermatozoa in their nutrient plasma, secretions from the prostate, seminal vesicles, and various other glands, epithelial cells, and minor constituents.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 371 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C78734 - SPECTYPE - Specimen Type Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C33529 SEMINAL FLUID Part of the ejaculated fluid. It contains secretions from Seminal Fluid the seminal vesicles, Cowper gland, and prostate gland.

C13325 SERUM Sera The clear portion of the blood that remains after the Serum removal of the blood cells and the clotting proteins. (NCI)

C33574 SMEGMA A white secretion of the sebaceous glands of the Smegma foreskin. (NCI)

C13278 SPUTUM Material containing mucus, cellular debris, Sputum microorganisms and sometimes blood or pus. It is ejected through the mouth from the lungs, bronchi, and trachea. (NCI)

C13234 STOOL Feces The material discharged from the bowel during Feces defecation. It consists of undigested food, intestinal mucus, epithelial cells, and bacteria. (NCI)

C33718 SYNOVIAL FLUID A viscid fluid secreted by the synovial membrane, Synovial Fluid serving as a lubricant. (NCI)

C12801 TISSUE An anatomical structure consisting of similarly Tissue specialized cells and intercellular matrix, aggregated according to genetically determined spatial relationships, performing a specific function. (NCI)

C78744 TRANSUDATE The fluid that passes through the wall of the veins and Transudate capillaries to the surrounding tissues because of increased intravascular pressure. It has low protein content. (NCI)

C13283 URINE The fluid that is excreted by the kidneys. It is stored in Urine the bladder and discharged through the urethra. (NCI)

C78730 VENOUS BLOOD Deoxygenated blood containing urea and other waste Venous Blood products which is transported through the venous system to the heart and lungs. The exception is blood within the pulmonary vein which is oxygenated and travels from the lungs to the left atrium of the heart. (NCI)

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 372 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C66728 - STENRF - Relation to Reference Period Codelist extensible: No

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C38008 AFTER The time period following a point or another period of Post time. (NCI)

C25629 BEFORE Earlier in time or order. (NCI) Prior

C25456 COINCIDENT Occurring or operating at the same time. Concurrent

C25490 DURING At some point in a given period of time. (NCI) During

C49640 DURING/AFTER Within a certain period of time or after a certain point During Or After or period in time. (NCI)

C53279 ONGOING Continuous Remain in force or carry on without letup; keep or Continue maintain in unaltered condition; exist in time or space without stop or interruption. (NCI)

C17998 U U; Unknown Not known, not observed, not recorded, or refused. Unknown (NCI)

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 373 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C99077 - STYPE - Study Type Codelist extensible: No

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C98722 EXPANDED ACCESS Studies that provide a means for obtaining an Expanded Access Study experimental drug or device for patients who are not adequately treated by existing therapy, who do not meet the eligibility criteria for enrollment, or who are otherwise unable to participate in another clinical study. Expanded Access studies include individual-patient IND, treatment IND, compassionate use, emergency use or continued access.

C98388 INTERVENTIONAL Studies in which individuals are assigned by an Interventional Study investigator based on a protocol to receive specific interventions. Subjects may receive diagnostic, therapeutic or other types of interventions. The assignment of the intervention may or may not be random. The individuals are then followed and biomedical and/or health outcomes are assessed.

C16084 OBSERVATIONAL Studies in which biomedical and/or health outcomes Observational Study are assessed in pre-defined groups of individuals. Subjects in the study may receive diagnostic, therapeutic, or other interventions, but the investigator does not assign specific interventions to the subjects of the study.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 374 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C66735 - TBLIND - Trial Blinding Schema Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C15228 DOUBLE BLIND A study in which neither the subject nor the Double Blind Study investigator nor the research team interacting with the subject or data during the trial knows what treatment a subject is receiving. (CDISC glossary)

C49659 OPEN LABEL A trial in which subjects and investigators know which Open Label Study product each subject is receiving; opposite of a blinded or double-blind study. (CDISC glossary)

C28233 SINGLE BLIND A study in which one party, either the investigator or Single Blind Study the subject, does not know which medication or placebo is administered to the subject; also called singlemasked study. (CDISC glossary)

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 375 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C66785 - TCNTRL - Control Type Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C49649 ACTIVE A type of control, which has a demonstrated effect, Active Control administered as a comparator, to subjects in a clinical trial. [From ICH E10].

C41132 NONE No person or thing, nobody, not any. (NCI) None

C49648 PLACEBO Use of an inactive compound identical in appearance to Placebo Control drug or treatment being tested in experimental research, which may or may not be known to the physician and/or subject, administered to distinguish between drug action and suggestive effect of the drug or treatment under study. The effects of the active drug or treatment are compared to the effects of the placebo. (NCI)

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 376 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C66787 - TDIGRP - Diagnosis Group Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C49651 HEALTHY SUBJECTS An individual who is or becomes a participant in a Healthy Subject research study and has no significant health-related issues. (NCI)

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 377 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C66736 - TINDTP - Trial Indication Type Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C49654 CURE A type of study protocol designed to evaluate Cure Study intervention(s) aimed to cure a disease or condition. (NCI)

C49653 DIAGNOSIS A type of study protocol designed to evaluate Diagnosis Study intervention(s) aimed at identifying a disease or condition. (NCI)

C49655 MITIGATION A type of study designed to identify actions necessary Adverse Effect Mitigation Study to eliminate or reduce the risk to human life or well-being as a result of a particular medication or treatment regimen. (NCI)

C49657 PREVENTION A type of study designed to identify actions necessary Prevention Study to permanently eliminate or reduce the long-term risk to human life as a result of a particular medication or treatment regimen.

C49656 TREATMENT A type of study protocol designed to evaluate Treatment Study intervention(s) for treatment of disease, syndrome or condition.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 378 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C66784 - TOXGR - Common Terminology Criteria for Adverse Events Codelist extensible: No

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C41338 1 Grade 1; 1 A type of adverse event that is usually transient and Mild Adverse Event may require only minimal treatment or therapeutic intervention. The event does not generally interfere with usual activities of daily living.

C41339 2 Grade 2; 2 A type of adverse event that is usually alleviated with Moderate Adverse Event additional specific therapeutic intervention. The event interferes with usual activities of daily living, causing discomfort but poses no significant or permanent risk of harm to the research participant.

C41340 3 Grade 3; 3 A type of adverse event that interrupts usual activities Severe Adverse Event of daily living, or significantly affects clinical status, or may require intensive therapeutic intervention.

C41337 4 Grade 4; 4; LIFE An adverse event, and/or its immediate sequelae, which Life Threatening or Disabling THREATENING is associated with an imminent risk of death or which Adverse Event is associated with physical or mental disabilities that affect or limit the ability of a person to perform activities of daily living (eating, ambulation, toileting, etc.) See NCI Common Terminology Criteria for Adverse Events.

C48275 5 Grade 5; 5; The termination of life as a result of an adverse event. Death Related to Adverse Event FATAL (NCI)

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 379 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C87162 - TOXGR - Common Terminology Criteria for Adverse Events V4.0 Codelist extensible: No

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C75533 0 ABSENT; Grade Grade 0 is universally defined as absence of Adverse Absent Adverse Event 0; 0 Events or within normal limits or values.

C84263 1 MILD; Grade 1; An adverse event that is asymptomatic; or involves Mild Adverse Event 1 mild or minor symptoms; or is of marginal clinical relevance; or consists of clinical or diagnostic observations alone; or for which intervention is not indicated; or for which only non-prescription intervention is indicated.

C84264 2 MODERATE; An adverse event for which only minimal, local, or Moderate Adverse Event Grade 2; 2 noninvasive intervention (e.g. packing, cautery) is indicated; or that limits instrumental activities of daily living (ADLs, e.g., shopping, laundry, transportation, or ability to conduct finances).

C84265 3 SEVERE; Grade An adverse event that is medically significant but not Severe Adverse Event 3; 3 life-threatening; or for which inpatient care or prolongation of hospitalization are indicated; or that is an important medical event that does not result in hospitalization, but may jeopardize the patient or may require intervention either to prevent hospitalization, to prevent the AE from becoming life-threatening or causing death; or that is disabling; or that results in persistent or significant disability, incapacity, or limitation of self care activities of daily living (ADLs, e.g., getting in and out of bed, dressing, eating, getting around inside, bathing, or using the toilet).

C84266 4 LIFE An adverse event that has life-threatening Life Threatening Adverse Event THREATENING; consequences; for which urgent intervention is Grade 4; 4 indicated; that puts the patient at risk of death at the time of the event if immediate intervention is not undertaken; or that causes blindness or deafness.

C48275 5 FATAL; Grade 5; The termination of life as a result of an adverse event. Death Related to Adverse Event 5 (NCI)

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 380 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C66737 - TPHASE - Trial Phase Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C48660 NA NA Determination of a value is not relevant in the current Not Applicable context. (NCI)

C15600 Phase I Trial Trial Phase 1; 1 The initial introduction of an investigational new drug Phase I Trial into humans. Phase 1 studies are typically closely monitored and may be conducted in patients or normal volunteer subjects. NOTE: These studies are designed to determine the metabolism and pharmacologic actions of the drug in humans, the side effects associated with increasing doses, and, if possible, to gain early evidence on effectiveness. During Phase 1, sufficient information about the drug's pharmacokinetics and pharmacological effects should be obtained to permit the design of well-controlled, scientifically valid, Phase 2 studies. The total number of subjects and patients included in Phase I studies varies with the drug, but is generally in the range of 20 to 80. Phase 1 studies also include studies of drug metabolism, structure-activity relationships, and mechanism of action in humans, as well as studies in which investigational drugs are used as research tools to explore biological phenomena or disease processes. [After FDA CDER Handbook, ICH E8] (CDISC glossary)

C15693 Phase I/II Trial Trial Phase 1-2; A class of clinical study that combines elements Phase I/II Trial 1-2 characteristic of traditional Phase I and Phase II trials. See also Phase I, Phase II.

C15601 Phase II Trial Trial Phase 2; 2 Phase 2. Controlled clinical studies conducted to Phase II Trial evaluate the effectiveness of the drug for a particular indication or indications in patients with the disease or condition under study and to determine the common short-term side effects and risks associated with the drug. NOTE: Phase 2 studies are typically well controlled, closely monitored, and conducted in a relatively small number of patients, usually involving no more than several hundred subjects. [After FDA CDER Handbook, ICH E8] (CDISC glossary)

C15694 Phase II/III Trial Trial Phase 2-3; A class of clinical study that combines elements Phase II/III Trial 2-3 characteristic of traditional Phase II and Phase III trials.

C15602 Phase III Trial Trial Phase 3; 3 Phase 3. Studies are expanded controlled and Phase III Trial uncontrolled trials. They are performed after preliminary evidence suggesting effectiveness of the drug has been obtained, and are intended to gather the additional information about effectiveness and safety that is needed to confirm efficacy and evaluate the overall benefit-risk relationship of the drug and to provide an adequate basis for physician labeling. NOTE: Phase 3 studies usually include from several hundred to several thousand subjects. [After FDA CDER Handbook, ICH E8] (CDISC glossary)

C49687 Phase IIIa Trial Trial Phase 3A; A classification typically assigned retrospectively to a Phase IIIa Trial 3A Phase III trial upon determination by regulatory authorities of a need for a Phase III B trial.

C49689 Phase IIIb Trial Trial Phase 3B; A subcategory of Phase III trials done near the time of Phase IIIb Trial 3B approval to elicit additional findings. NOTE: Dossier review may continue while associated Phase IIIB trials are conducted. These trials may be required as a condition of regulatory authority approval.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 381 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C66737 - TPHASE - Trial Phase Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C49686 Phase IIa Trial Trial Phase 2A; A clinical research protocol generally referred to as a Phase IIa Trial 2A pilot or feasibility trial that aims to prove the concept of the new intervention in question. (NCI)

C49688 Phase IIb Trial Trial Phase 2B; A clinical research protocol generally referred to as a Phase IIb Trial 2B well-controlled and pivotal trial that aims to prove the mechanism of action of the new intervention in question. A pivotal study will generally be well-controlled, randomized, of adequate size, and whenever possible, double-blind. (NCI)

C15603 Phase IV Trial Trial Phase 4; 4 Phase 4. Postmarketing (Phase 4) studies to delineate Phase IV Trial additional information about the drug's risks, benefits, and optimal use that may be requested by regulatory authorities in conjunction with marketing approval. NOTE: These studies could include, but would not be limited to, studying different doses or schedules of administration than were used in Phase 2 studies, use of the drug in other patient populations or other stages of the disease, or use of the drug over a longer period of time. [After FDA CDER Handbook, ICH E8] (CDISC glossary)

C47865 Phase V Trial Trial Phase 5; 5 Postmarketing surveillance is sometimes referred to Phase V Trial as Phase V.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 382 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C96778 - TRTEST - Oncology Tumor Properties Test Name Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C25244 Area Area The extent of a 2-dimensional surface enclosed within Area a boundary. (NCI)

C96566 Average Metabolic Standard Average A semiquantitative analysis of the average uptake of Average Metabolic Standard Uptake Uptake Value Metabolic analyte by body tissue in relation to the total Value Standard Uptake administered dose of the analyte. Value

C25285 Diameter Diameter The length of a straight line passing through the center Diameter of a circle or sphere and connecting two points on the circumference. (NCI)

C96684 Longest Diameter Longest The longest possible length of a straight line passing Longest Diameter Diameter through the center of a circular or spheroid object that connects two points on the circumference.

C96685 Longest Perpendicular Longest The longest possible straight line or plane through a Longest Perpendicular Perpendicular body or figure that is at a right angle to a given line or plane.

C96621 Percent Change From Percent Change The value of the current measurement divided by the Percent Change From Baseline Baseline From Baseline initial value, taken at some baseline event or timepoint, multiplied by 100.

C96622 Percent Change From Nadir Percent Change The value of the current measurement divided by the Percent Change From Nadir From Nadir lowest value previously recorded multiplied by 100.

C96627 Radiodensity Radiodensity The transparency of a material to the passage of X-rays Radiodensity and other forms of radiation.

C94982 Short Axis Short Axis The plane through a body or figure that is at the Short Axis shortest width of that body or figure.

C96630 Sum of Area Sum of Area A calculation of the aggregated area values. Sum of Areas

C96631 Sum of Diameter Sum of Diameter A calculation of the aggregated diameter values. Sum of Diameters

C96632 Sum of Longest Diameter Sum of Longest A calculation of the aggregated longest diameter Sum of Longest Diameters Diameter values.

C96633 Sum of Longest Perpendicular Sum of Longest A calculation of the aggregated longest perpendicular Sum of Longest Perpendiculars Perpendicular values.

C96634 Sum of Viable Diameter Sum of Viable A calculation of the aggregated diameter values taken Sum of Viable Diameters Diameter from the viable portion of the tumor mass.

C96635 Sum of Volume Sum of Volume A calculation of the aggregated volume values. Sum of Volumes

C96643 Tumor State Tumor State A condition or state of a tumor at a particular time. Tumor Status

C96646 Viable Diameter Viable Diameter The diameter of the portion of the tumor mass that is Viable Tumor Diameter capable of growth, proliferation and metastasis.

C25335 Volume Volume The amount of three dimensional space occupied by an Volume object or the capacity of a space or container. (NCI)

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 383 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C96779 - TRTESTCD - Oncology Tumor Properties Test Code Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C25244 AREA Area The extent of a 2-dimensional surface enclosed within Area a boundary. (NCI)

C96566 AVMETSUV Average A semiquantitative analysis of the average uptake of Average Metabolic Standard Uptake Metabolic analyte by body tissue in relation to the total Value Standard Uptake administered dose of the analyte. Value

C25285 DIAMETER Diameter The length of a straight line passing through the center Diameter of a circle or sphere and connecting two points on the circumference. (NCI)

C96684 LDIAM Longest The longest possible length of a straight line passing Longest Diameter Diameter through the center of a circular or spheroid object that connects two points on the circumference.

C96685 LPERP Longest The longest possible straight line or plane through a Longest Perpendicular Perpendicular body or figure that is at a right angle to a given line or plane.

C96621 PCHGBL Percent Change The value of the current measurement divided by the Percent Change From Baseline From Baseline initial value, taken at some baseline event or timepoint, multiplied by 100.

C96622 PCHGNAD Percent Change The value of the current measurement divided by the Percent Change From Nadir From Nadir lowest value previously recorded multiplied by 100.

C96627 RADIODEN Radiodensity The transparency of a material to the passage of X-rays Radiodensity and other forms of radiation.

C94982 SAXIS Short Axis The plane through a body or figure that is at the Short Axis shortest width of that body or figure.

C96630 SUMAREA Sum of Area A calculation of the aggregated area values. Sum of Areas

C96631 SUMDIAM Sum of Diameter A calculation of the aggregated diameter values. Sum of Diameters

C96632 SUMLDIAM Sum of Longest A calculation of the aggregated longest diameter Sum of Longest Diameters Diameter values.

C96633 SUMLPERP Sum of Longest A calculation of the aggregated longest perpendicular Sum of Longest Perpendiculars Perpendicular values.

C96634 SUMVDIAM Sum of Viable A calculation of the aggregated diameter values taken Sum of Viable Diameters Diameter from the viable portion of the tumor mass.

C96635 SUMVOL Sum of Volume A calculation of the aggregated volume values. Sum of Volumes

C96643 TUMSTATE Tumor State A condition or state of a tumor at a particular time. Tumor Status

C96646 VDIAM Viable Diameter The diameter of the portion of the tumor mass that is Viable Tumor Diameter capable of growth, proliferation and metastasis.

C25335 VOLUME Volume The amount of three dimensional space occupied by an Volume object or the capacity of a space or container. (NCI)

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 384 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C67152 - TSPARM - Trial Summary Parameter Test Name Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C98703 Actual Number of Subjects Actual Number Actual number of subjects enrolled; may include Actual Subject Number of Subjects subjects who were not randomized.

C98704 Adaptive Design Adaptive Design Indicate if the study includes a prospectively planned Adaptive Design opportunity for modification of one or more specified aspects of the study design and hypotheses based on analysis of data (usually interim data) from subjects in the study.

C49703 Added on to Existing Added on to The addition of a therapeutic product to the existing Test Product Added to Existing Treatments Existing regimen in a clinical trial, where both entities remain Treatment Treatments as discrete products.

C20587 Age Span Age Span Subgroups of populations based on age. (NCI) Age Group

C70793 Clinical Study Sponsor Clinical Study An entity that is responsible for the initiation, Clinical Study Sponsor Sponsor; Study management, and/or financing of a clinical study. Sponsor; Sponsor

C68612 Comparative Treatment Name Comparative A therapeutically active agent that is intended to Active Comparator Drug Treatment Name provide reference measurements for the experimental protocol of a clinical trial.

C98715 Confirmed Response Confirmed The protocol specified minimum amount of time Confirmed Response Minimum Minimum Duration Response needed to meet the definition of a confirmed response Duration Minimum to treatment. Duration

C49647 Control Type Control Type Comparator against which the study treatment is Control Type evaluated (e.g., concurrent (placebo, no treatment, dose-response, active), external (historical, published literature).

C85582 Current Therapy or Treatment Current Therapy The literal identifier of the therapy or medication that Current Therapy or Treatment is currently being given per protocol. This does not include treatment that has been given in the past.

C98717 Data Cutoff Date Data Cutoff Date A date which indicates any data collected by this date Data Cutoff Date will be used for analysis.

C98718 Data Cutoff Description Data Cutoff Text that describes the cutoff date. Data Cutoff Date Description Description

C49650 Diagnosis Group Diagnosis Group A grouping of individuals on the basis of a shared Diagnosis Group procedure or disease, or lack thereof (e.g. healthy volunteers, type 2 diabetic subjects, subjects with renal cell cancer). Standardized naming systems are available that define the groups within which a subject should be placed. (NCI)

C73558 Dose Units Dose Units The unit of measure for the dosage form. Dosage Form Unit

C25488 Dose per Administration Dose per The amount of drug administered to a patient or test Dose Administration subject at one time or the total quantity administered. [AMA Manual of Style] (CDISC Glossary)

C89081 Dosing Frequency Dosing The number of doses administered per a specific Dose Frequency Frequency interval.

C98724 Exploratory Outcome Exploratory Exploratory measures that will be used to evaluate the Exploratory Outcome Measure Measure Outcome intervention(s) or, for observational studies, that are Measure exploratory of the study.

C98737 Healthy Subject Indicator Healthy Subject Indicate if persons who have not had the condition(s) Healthy Subject Indicator Indicator being studied or otherwise related conditions or symptoms, as specified in the eligibility requirements, may participate in the study.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 385 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C67152 - TSPARM - Trial Summary Parameter Test Name Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C98746 Intervention Model Intervention The trial design developed to compare treatment Intervention Model Model groups.

C98747 Intervention Type Intervention Type The kind of product or procedure studied in a trial. Intervention Type

C41161 Investigational Therapy or Investigational The investigational product under study. Protocol Agent Treatment Therapy or Treatment

C98768 Pharmacological Class of Pharmacological The pharmacological class of the investigational Pharmacological Class of Investigational Therapy Class of product. Investigational Therapy Investigational Therapy

C98770 Planned Country of Planned Country The country name of planned study facility which has Planned Country of Investigational Investigational Site(s) of Investigational received IRB approval. Site Site(s)

C49694 Planned Maximum Age of Planned The anticipated maximum age of the subjects to be Planned Maximum Age of Subjects Subjects Maximum Age of entered in a clinical trial. (NCI) Subjects

C49693 Planned Minimum Age of Planned The anticipated minimum age of the subjects to be Planned Minimum Age of Subjects Subjects Minimum Age of entered in a clinical trial. (NCI) Subjects

C98771 Planned Number of Arms Planned Number The planned number of intervention groups. Planned Number of Arms of Arms

C49692 Planned Number of Subjects Planned Number The planned number of subjects to be entered in a Planned Subject Number of Subjects; clinical trial. (NCI) Planned Enrollment; Target Enrollment; Anticipated Enrollment

C98772 Primary Outcome Measure Primary The primary measurement(s) or observation(s) used to Primary Outcome Measure Outcome measure the effect of experimental variables in a Measure study, or for observational studies, to describe patterns of diseases or traits or associations with exposures, risk factors or treatment. These are the outcome measures used to assess the primary objective(s).

C98775 Randomization Quotient Randomization The randomization quotient is the number of planned Randomization Quotient Quotient subjects to be exposed to investigational therapy, independent of dose or other factors, divided by the total number of planned subjects.

C98714 Registry Identifier Registry Identification numbers assigned to the protocol by Clinical Trial Registry Identifier Identifier ct.gov, EudraCT, or other registries.

C38114 Route of Administration Route of The course by which a substance was administered in Route of Administration Administration order to reach the site of action in the body.

C98781 Secondary Outcome Measure Secondary Other key measures that will be used to evaluate the Secondary Outcome Measure Outcome intervention(s) or, for observational studies, that are a Measure focus of the study. These are the outcome measures used to assess the secondary objective(s).

C49696 Sex of Participants Sex of The specific sex, either male, female, or mixed of the Sex of Study Group Participants subject group being studied. (NCI)

C98783 Stable Disease Minimum Stable Disease The protocol specified minimum amount of time Stable Disease Minimum Duration Duration Minimum needed to meet the definition of stable disease. Duration

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 386 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C67152 - TSPARM - Trial Summary Parameter Test Name Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C90462 Study End Date Study End Date Final date on which data was collected for any subject Study End Date (Date/Time of End of Participation, RFPENDTC) based on the protocol.

C69208 Study Start Date Study Start Date The earliest date of informed consent among any Study Date subject (Date/Time of Informed Consent, RFICDTC) that enrolled in the study. For studies conducted without informed consent (ie. emergency use) use the date of treatment. Dates for subjects who were screen failures are not included.

C49698 Study Stop Rules Study Stop Rules The rule, regulation and/or condition that determines Study Stop Rules the point in time when a clinical trial will be terminated. (NCI)

C15320 Study Type Study Type Describes the role the study plays in determining the Study Design interventions a subject receives.

C49658 Trial Blinding Schema Trial Blinding The name of a code list that contains terms to define Trial Blinding Schema Schema the type of blinding for the trial. (NCI)

C41184 Trial Indication Trial Indication The basis for initiation of a treatment for a disease or Indication of a diagnostic test (causal, or symptomatic, or disease-specific indication).

C49652 Trial Indication Type Trial Indication The name of a code list that contains terms to define Trial Indication Type Type the type of trial, e.g. cure or prevention. (NCI)

C49697 Trial Length Trial Length Planned length of observation for a single subject. Trial Length

C48281 Trial Phase Classification Trial Phase Clinical trials are broken into three or four phases: Trial Phase Classification Phase I tests a new drug or treatment for safety in a small group; Phase II expands the study to a larger group of people; Phase III expands the study to an even larger group of people to measure whether the treatment actually benefits patients, and whether its benefits exceed its risks; and Phase IV takes place after the drug or treatment has been licensed and marketed. (NCI)

C85826 Trial Primary Objective Trial Primary The principal purpose of the trial. Trial Primary Objective Objective

C85827 Trial Secondary Objective Trial Secondary The auxiliary purpose of the trial. Trial Secondary Objective Objective

C49802 Trial Title Trial Title The name of a clinical trial. (NCI) Trial Title

C49660 Trial Type Trial Type The type of clinical trial performed e.g. efficacy, Trial Type safety. (NCI)

C25196 Trial is Randomized Trial is The process of assigning trial subjects to treatment or Randomization Randomized control groups using an element of chance to determine the assignments in order to reduce bias. NOTE: Unequal randomization is used to allocate subjects into groups at a differential rate; for example, three subjects may be assigned to a treatment group for every one assigned to the control group. [ICH E6 1.48] See also balanced study. (CDISC glossary)

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 387 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C66738 - TSPARMCD - Trial Summary Parameter Test Code Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C98703 ACTSUB Actual Number Actual number of subjects enrolled; may include Actual Subject Number of Subjects subjects who were not randomized.

C98704 ADAPT Adaptive Design Indicate if the study includes a prospectively planned Adaptive Design opportunity for modification of one or more specified aspects of the study design and hypotheses based on analysis of data (usually interim data) from subjects in the study.

C49703 ADDON Added on to The addition of a therapeutic product to the existing Test Product Added to Existing Existing regimen in a clinical trial, where both entities remain Treatment Treatments as discrete products.

C49694 AGEMAX Planned The anticipated maximum age of the subjects to be Planned Maximum Age of Subjects Maximum Age of entered in a clinical trial. (NCI) Subjects

C49693 AGEMIN Planned The anticipated minimum age of the subjects to be Planned Minimum Age of Subjects Minimum Age of entered in a clinical trial. (NCI) Subjects

C20587 AGESPAN Age Span Subgroups of populations based on age. (NCI) Age Group

C68612 COMPTRT Comparative A therapeutically active agent that is intended to Active Comparator Drug Treatment Name provide reference measurements for the experimental protocol of a clinical trial.

C98715 CRMDUR Confirmed The protocol specified minimum amount of time Confirmed Response Minimum Response needed to meet the definition of a confirmed response Duration Minimum to treatment. Duration

C85582 CURTRT Current Therapy The literal identifier of the therapy or medication that Current Therapy or Treatment is currently being given per protocol.

C98718 DCUTDESC Data Cutoff Text that describes the cutoff date. Data Cutoff Date Description Description

C98717 DCUTDTC Data Cutoff Date A date which indicates any data collected by this date Data Cutoff Date will be used for analysis.

C25488 DOSE Dose per The amount of drug administered to a patient or test Dose Administration subject at one time or the total quantity administered. [AMA Manual of Style] (CDISC Glossary)

C89081 DOSFRQ Dosing The number of doses administered per a specific Dose Frequency Frequency interval.

C73558 DOSU Dose Units The unit of measure for the dosage form. Dosage Form Unit

C98770 FCNTRY Planned Country The country name of planned study facility which has Planned Country of Investigational of Investigational received IRB approval. Site Site(s)

C98737 HLTSUBJI Healthy Subject Indicate if persons who have not had the condition(s) Healthy Subject Indicator Indicator being studied or otherwise related conditions or symptoms, as specified in the eligibility requirements, may participate in the study.

C41184 INDIC Trial Indication The basis for initiation of a treatment for a disease or Indication of a diagnostic test (causal, or symptomatic, or disease-specific indication).

C98746 INTMODEL Intervention The trial design developed to compare treatment Intervention Model Model groups.

C98747 INTTYPE Intervention Type The kind of product or procedure studied in a trial. Intervention Type

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 388 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C66738 - TSPARMCD - Trial Summary Parameter Test Code Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C49697 LENGTH Trial Length Planned length of observation for a single subject. Trial Length

C98771 NARMS Planned Number The planned number of intervention groups. Planned Number of Arms of Arms

C85826 OBJPRIM Trial Primary The principal purpose of the trial. Trial Primary Objective Objective

C85827 OBJSEC Trial Secondary The auxiliary purpose of the trial. Trial Secondary Objective Objective

C98724 OUTMSEXP Exploratory Exploratory measures that will be used to evaluate the Exploratory Outcome Measure Outcome intervention(s) or, for observational studies, that are Measure exploratory of the study.

C98772 OUTMSPRI Primary The primary measurement(s) or observation(s) used to Primary Outcome Measure Outcome measure the effect of experimental variables in a Measure study, or for observational studies, to describe patterns of diseases or traits or associations with exposures, risk factors or treatment. These are the outcome measures used to assess the primary objective(s).

C98781 OUTMSSEC Secondary Other key measures that will be used to evaluate the Secondary Outcome Measure Outcome intervention(s) or, for observational studies, that are a Measure focus of the study. These are the outcome measures used to assess the secondary objective(s).

C98768 PCLAS Pharmacological The pharmacological class of the investigational Pharmacological Class of Class of product. Investigational Therapy Investigational Therapy

C49692 PLANSUB Planned Number The planned number of subjects to be entered in a Planned Subject Number of Subjects; clinical trial. (NCI) Planned Enrollment; Target Enrollment; Anticipated Enrollment

C25196 RANDOM Trial is The process of assigning trial subjects to treatment or Randomization Randomized control groups using an element of chance to determine the assignments in order to reduce bias. NOTE: Unequal randomization is used to allocate subjects into groups at a differential rate; for example, three subjects may be assigned to a treatment group for every one assigned to the control group. [ICH E6 1.48] See also balanced study. (CDISC glossary)

C98775 RANDQT Randomization The randomization quotient is the number of planned Randomization Quotient Quotient subjects to be exposed to investigational therapy, independent of dose or other factors, divided by the total number of planned subjects.

C98714 REGID Registry Identification numbers assigned to the protocol by Clinical Trial Registry Identifier Identifier ct.gov, EudraCT, or other registries.

C38114 ROUTE Route of The course by which a substance was administered in Route of Administration Administration order to reach the site of action in the body.

C98783 SDMDUR Stable Disease The protocol specified minimum amount of time Stable Disease Minimum Duration Minimum needed to meet the definition of stable disease. Duration

C90462 SENDTC Study End Date Final date on which data was collected for any subject Study End Date (Date/Time of End of Participation, RFPENDTC) based on the protocol.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 389 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C66738 - TSPARMCD - Trial Summary Parameter Test Code Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C49696 SEXPOP Sex of The specific sex, either male, female, or mixed of the Sex of Study Group Participants subject group being studied. (NCI)

C70793 SPONSOR Clinical Study An entity that is responsible for the initiation, Clinical Study Sponsor Sponsor; Study management, and/or financing of a clinical study. Sponsor; Sponsor

C69208 SSTDTC Study Start Date The earliest date of informed consent among any Study Date subject (Date/Time of Informed Consent, RFICDTC) that enrolled in the study. For studies conducted without informed consent (ie. emergency use) use the date of treatment. Dates for subjects who were screen failures are not included.

C49698 STOPRULE Study Stop Rules The rule, regulation and/or condition that determines Study Stop Rules the point in time when a clinical trial will be terminated. (NCI)

C15320 STYPE Study Type Describes the role the study plays in determining the Study Design interventions a subject receives.

C49658 TBLIND Trial Blinding The name of a code list that contains terms to define Trial Blinding Schema Schema the type of blinding for the trial. (NCI)

C49647 TCNTRL Control Type Comparator against which the study treatment is Control Type evaluated (e.g., concurrent (placebo, no treatment, dose-response, active), external (historical, published literature).

C49650 TDIGRP Diagnosis Group A grouping of individuals on the basis of a shared Diagnosis Group procedure or disease, or lack thereof (e.g. healthy volunteers, type 2 diabetic subjects, subjects with renal cell cancer). Standardized naming systems are available that define the groups within which a subject should be placed. (NCI)

C49652 TINDTP Trial Indication The name of a code list that contains terms to define Trial Indication Type Type the type of trial, e.g. cure or prevention. (NCI)

C49802 TITLE Trial Title The name of a clinical trial. (NCI) Trial Title

C48281 TPHASE Trial Phase Clinical trials are broken into three or four phases: Trial Phase Classification Phase I tests a new drug or treatment for safety in a small group; Phase II expands the study to a larger group of people; Phase III expands the study to an even larger group of people to measure whether the treatment actually benefits patients, and whether its benefits exceed its risks; and Phase IV takes place after the drug or treatment has been licensed and marketed. (NCI)

C41161 TRT Investigational The investigational product under study. Protocol Agent Therapy or Treatment

C49660 TTYPE Trial Type The type of clinical trial performed e.g. efficacy, Trial Type safety. (NCI)

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 390 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C66739 - TTYPE - Trial Type Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C49664 BIO-AVAILABILITY A study of the degree to which or rate at which a drug Bioavailability Study or other substance is absorbed or becomes available at the site of physiological activity after administration. (NCI)

C49665 BIO-EQUIVALENCE A study most often used to compare the efficacy of Therapeutic Equivalency Study different formulations to treat a given disease. It is the testing of an old versus a new formulation in healthy volunteers or subjects with the disease under study and usually in one dose. (NCI)

C49666 EFFICACY A study of the relative therapeutic efficacy of Efficacy Study treatment of a disease. Usually this is a Phase II or III study. (NCI)

C98729 FOOD EFFECT Studies that are conducted to assess the effect of food Food Effect Study on the rate and extent of absorption of a drug, either compared to a fasted state or to a reference drug.

C49662 PHARMACODYNAMIC A study of the biochemical and physiological effect of Pharmacodynamic Study a drug and the mechanism of drug action and the relationship between drug concentration and effect. (NCI)

C39493 PHARMACOECONOMIC A study that assesses the value associated with a given Pharmacoeconomic Study drug in therapeutic and economic terms. This type of study is multidisciplinary in nature and takes into consideration the social and economic costs (resource utilization costs including direct, indirect, and intangible costs) of drug therapy in addition to its direct therapeutic benefits. Analyses relate the difference in therapeutic benefits to the difference in costs between treatment alternatives. (NCI)

C49661 PHARMACOGENOMIC A study of identification and analysis of genomic Pharmacogenomic Study variations that affect the efficacy of a drug. Pharmacogenomic studies can potentially be predictive of an individual's drug-response or adverse reactions or susceptibility to iatrogenic disorders, and may also reveal new targets that can help in the design of new drugs. (NCI)

C49663 PHARMACOKINETIC A study of the process by which a drug is absorbed, Pharmacokinetic Study distributed, metabolized, and eliminated by the body. (NCI)

C49667 SAFETY A study that assesses the medical risks to a subject. Safety Study Safety is usually assessed by examining a wide range of clinical parameters, including adverse events, vital signs, physical exam, laboratory tests.

C98791 TOLERABILITY A type of safety study thatassesses the degree to which Tolerability Study overt adverse effects can be toleratedby the subject.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 391 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C96780 - TUMIDENT - Tumor Identification Results Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C94522 NEW The identification of a tumor which has not been New Lesion Identification previously seen or characterized.

C94521 NON-TARGET The identification of a tumor or site of disease that is Non-Target Lesion Identification present at baseline and not considered a target tumor, but may be part of the objective assessment of the response to the therapeutic intervention.

C94520 TARGET The identification of a tumor that is present at Target Lesion Identification baseline, is measurable and is the primary target of the therapeutic intervention.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 392 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C96783 - TUTEST - Tumor Identification Test Name Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C94523 Tumor Identification Tumor An indication that a tumor has been located and Tumor Identification Identification characterized.

C94525 Tumor Merged Tumor Merged An indication that multiple tumors have coalesced into Matted Tumor Mass Present one tumor.

C96642 Tumor Split Tumor Split An indication that a single tumor has divided into two Tumor Split or more tumors.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 393 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C96784 - TUTESTCD - Tumor Identification Test Code Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C94525 TUMERGE Tumor Merged An indication that multiple tumors have coalesced into Matted Tumor Mass Present one tumor.

C94523 TUMIDENT Tumor An indication that a tumor has been located and Tumor Identification Identification characterized.

C96642 TUSPLIT Tumor Split An indication that a single tumor has divided into two Tumor Split or more tumors.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 394 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C71620 - UNIT - Unit Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C25613 % Percentage A fraction or ratio with 100 understood as the Percentage denominator. (NCI)

C48571 %(v/v) Percent Volume A percent ratio of volume to volume, defined by the Percent Volume per Volume per Volume equation: [volume of solute (in ml)/ volume of solution (in ml)](100), typically used for admixtures of solutions.(NCI)

C48527 %(w/v) Percent Weight A percent ratio of weight to volume, defined by the Percent Mass per Volume per Volume equation: [weight of solute (in gm)/volume of solution (in dl)](100). Since the numerator and denominator of this ratio have different units, it is not a true percentage. A 1% w/v solution is defined as being 1 gram of solute dissolved in 100 milliliters of solvent.(NCI)

C48528 %(w/w) Percent Weight A percent ratio of weight to weight, defined by the Percent Mass per Mass per Weight equation: [weight of solute (in gm)/weight of solution (in gm)](100).(NCI)

C96619 /HPF per High A unit of measure equal to the instances of an entity Per High Powered Field Powered Field per visual field of a microscope set to its maximum magnification power.

C96620 /LPF per Low A unit of measure equal to the instances of an entity Per Low Powered Field Powered Field per visual field of a microscope set to its minimum magnification power.

C66968 /day Per Day A frequency rate of occurrences of something within a /day period of time equal to twenty-four hours. (NCI)

C66966 /h Per Hour A rate of occurrences of something within a period of /h time equal to sixty minutes.

C67254 /uL Per Microliter A volume unit equal to one microliter used as a /uL denominator to build a derived unit expressed as a ratio. (NCI)

C67069 /wk Every week; Per Every week. (NCI) Weekly Week

C71185 100 IU/mL 100 International A unit of arbitrary substance concentration (biologic 100 International Units per Milliliter units/Milliliter activity concentration) defined as the concentration of one hundred international units per one milliliter of system volume.(NCI)

C67308 10^12/L 10^6/uL A unit of measurement equal to 10 to the twelfth Million per Microliter power of the number of entities per unit of volume equal to one liter.

C68895 10^3 CFU Thousand Colony A unit of measurement of viable bacterial numbers Thousand Colony Forming Units Forming Units; equal to 10 to the third power colony forming units. Thousand CFU

C68899 10^3 CFU/g Thousand Colony A unit of measurement of viable bacterial organisms in Thousand Colony Forming Units per Forming Units a unit mass of substance of interest defined as the Gram per Gram; number of 10 to the third power colony forming units Thousand CFU/g in one gram of substance.

C68903 10^3 CFU/mL Thousand Colony A unit of measurement of viable bacterial organisms in Thousand Colony Forming Units per Forming Units a unit volume of substance of interest defined as the Milliliter per Milliliter; number of 10 to the third power colony forming units Thousand in one milliliter of substance. CFU/mL

C98788 10^3 DNA copies/mL A unit of measurement equal to 10 to the third power Thousand DNA Copies per Milliliter of the number of deoxyribonucleic acid (DNA) copies per unit of volume equal to one milliliter.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 395 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C71620 - UNIT - Unit Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C98790 10^3 RNA copies/mL A unit of measurement equal to 10 to the third power Thousand RNA Copies per Milliliter of the number of ribonucleic acid (RNA) copies per unit of volume equal to one milliliter.

C100897 10^3 copies/mL The unit of concentration expressed as the number of Thousand Copies per Milliliter 10 to the third power copies in unit volume equal to one milliliter. (NCI)

C71187 10^3 organisms Thousand A unit of measure of quantity of organisms expressed Thousand Organisms Organisms in 10 to the third power of organisms.

C71190 10^3 organisms/g Thousand A unit of measure of organism content expressed in 10 Thousand Organisms per Gram Organisms per to the third power of organisms per unit of mass equal Gram; Thousand to one gram. Organisms/g

C71195 10^3 organisms/mL Thousand A unit of measure of organism concentration Thousand Organisms per Milliliter Organisms per expressed in 10 to the third power of organisms per Milliliter; unit of volume equal to one milliliter. Thousand Organisms/mL

C98789 10^3/hpf A unit of measurement equal to 10 to the third power Thousand per High Powered Field of the number of entities per unit of area equal to one high powered field.

C98787 10^4/hpf A unit of measurement equal to 10 to the fourth power Ten Thousand per High Powered of the number of entities per unit of area equal to one Field high powered field.

C98743 10^5/hpf A unit of measurement equal to 10 to the fifth power Hundred Thousand per High Powered of the number of entities per unit of area equal to one Field high powered field.

C68896 10^6 CFU Million Colony A unit of measurement of viable bacterial numbers Million Colony Forming Units Forming Units; equal to 10 to the sixth power colony forming units. Million CFU

C68900 10^6 CFU/g Million Colony A unit of measurement of viable bacterial organisms in Million Colony Forming Units per Forming Units a unit mass of substance of interest defined as the Gram per Gram; number of 10 to the sixth power colony forming units Million CFU/g in one gram of substance.

C68904 10^6 CFU/mL Million Colony A unit of measurement of viable bacterial organisms in Million Colony Forming Units per Forming Units a unit volume of substance of interest defined as the Milliliter per Milliliter; number of 10 to the sixth power colony forming units Million CFU/mL in one milliliter of substance.

C98756 10^6 DNA copies/mL A unit of measurement equal to 10 to the sixth power Million DNA Copies per Milliliter of the number of deoxyribonucleic acid (DNA) copies per unit of volume equal to one milliliter.

C67335 10^6 IU Million A unit of biological activity equal to 10 to the sixth Million International Units International power international units. Units; Million IU

C98757 10^6 IU/mL A unit of measurement equal to 10 to the sixth power Million International Units per of the number of international units of an entity per Milliliter unit of volume equal to one milliliter.

C98760 10^6 RNA copies/mL A unit of measurement equal to 10 to the sixth power Million RNA Copies per Milliliter of the number of ribonucleic acid (RNA) copies per unit of volume equal to one milliliter.

C100898 10^6 copies/mL The unit of concentration expressed as the number of Million Copies per Milliliter 10 to the sixth power copies in unit volume equal to one milliliter. (NCI)

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 396 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C71620 - UNIT - Unit Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C71188 10^6 organisms Million A unit of measure of quantity of organisms expressed Million Organisms Organisms in 10 to the sixth power of organisms.

C71191 10^6 organisms/g Million A unit of measure of organism content expressed in 10 Million Organisms per Gram Organisms per to the sixth power of organisms per unit of mass equal Gram; Million to one gram. Organisms/g

C71196 10^6 organisms/mL Million A unit of measure of organism concentration Million Organisms per Milliliter Organisms per expressed in 10 to the sixth power of organisms per Milliliter; unit of volume equal to one milliliter. Million Organisms/mL

C71193 10^6 organisms/mg Million A unit of measure of organism content expressed in 10 Million Organisms per Milligram Organisms per to the sixth power of organisms per unit of mass equal Milligram; to one milligram. Million Organisms/mg

C67452 10^6/L 10^3/mL A unit of measurement equal to 10 to the sixth power Thousand per Milliliter of the number of entities per unit of volume equal to one liter.

C98758 10^6/g A unit of measurement equal to 10 to the sixth power Million per Gram of the number of entities per unit of mass equal to one gram.

C98759 10^6/hpf A unit of measurement equal to 10 to the sixth power Million per High Powered Field of the number of entities per unit of area equal to one high powered field.

C98786 10^7/L 10^6/dL A unit of measurement equal to 10 to the seventh Ten Million per Liter power of the number of entities per unit of volume equal to one liter.

C68897 10^9 CFU Billion Colony A unit of measurement of viable bacterial numbers Billion Colony Forming Units Forming Units; equal to 10 to the ninth power colony forming units. Billion CFU

C68901 10^9 CFU/g Billion Colony A unit of measurement of viable bacterial organisms in Billion Colony Forming Units per Forming Units a unit mass of substance of interest defined as the Gram per Gram; number of 10 to the ninth power colony forming units Billion CFU/g in one gram of substance.

C68905 10^9 CFU/mL Billion Colony A unit of measurement of viable bacterial organisms in Billion Colony Forming Units per Forming Units a unit volume of substance of interest defined as the Milliliter per Milliliter; number of 10 to the ninth power colony forming units Billion CFU/mL in one milliliter of substance.

C71189 10^9 organisms Billion A unit of measure of quantity of organisms expressed Billion Organisms Organisms in 10 to the ninth power of organisms.

C71192 10^9 organisms/g Billion A unit of measure of organism content expressed in 10 Billion Organisms per Gram Organisms per to the ninth power of organisms per unit of mass equal Gram; Billion to one gram. Organisms/g

C71197 10^9 organisms/mL Billion A unit of measure of organism concentration Billion Organisms per Milliliter Organisms per expressed in 10 to the ninth power of organisms per Milliliter; unit of volume equal to one milliliter. Billion Organisms/mL

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 397 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C71620 - UNIT - Unit Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C71194 10^9 organisms/mg Billion A unit of measure of organism content expressed in 10 Billion Organisms per Milligram Organisms per to the ninth power of organisms per unit of mass equal Milligram; to one milligram. Billion Organisms/mg

C67255 10^9/L 10^3/uL;10^3/ A unit of measurement equal to 10 to the ninth power Billion per Liter mm3 of the number of entities per unit of volume equal to one liter.

C77534 AFU Arbitrary Arbitrary unit(s) of fluorescent luminescence. (NCI) Arbitrary Fluorescence Units Fluorescence Unit

C48473 AMPULE Ampule Dosing A dosing measurement based on the ampule unit.(NCI) Ampule Dosing Unit Unit

C73686 AU Absorbance Unit A unit of optical density expressed as the absorbance AU of light transmitted through the medium on the logarithmic scale. (NCI)

C70504 AU/mL Allergy Unit per Unit of measure of potency of allergenic product Allergy Unit per Milliliter Milliliter expressed as a number of allergy units per one milliliter of formulation.(NCI)

C73687 AU/min Absorbance Unit A unit of a speed of optical density change expressed AU/min per Minute as a logarithm of absorbance of light transmitted through a partially absorbing substance per minute. (NCI)

C70500 AgU/mL Antigen Unit per A measure of an antigen potency defined as a number Antigen Unit per Milliliter Milliliter of antigen units per one milliliter of product.(NCI)

C48474 BAG Bag Dosing Unit A dosing measurement based on the bag unit.(NCI) Bag Dosing Unit

C48475 BAR Bar Dosing Unit A dosing measurement based on the bar unit.(NCI) Bar Dosing Unit

C70505 BAU Bioequivalent A unit used for standardization of an allergenic product Bioequivalent Allergy Unit Allergy Unit based on evaluation of product potency against reference standard in combined in vivo (skin test) and in vitro (IgE-based ELISA) testing.(NCI)

C49673 BEATS/MIN Beats per Minute The number of heartbeats measured per minute time. Beats per Minute (NCI)

C48476 BOLUS Bolus Dosing A dosing measurement based on the bolus unit.(NCI) Bolus Dosing Unit Unit

C48477 BOTTLE Bottle Dosing A dosing measurement based on the bottle unit.(NCI) Bottle Dosing Unit Unit

C48478 BOX Box Dosing Unit A dosing measurement based on the box unit.(NCI) Box Dosing Unit

C49674 BREATHS/MIN Breaths per The number of breaths (inhalation and exhalation) Breaths per Minute Minute taken per minute time. (NCI)

C42562 Bq Becquerel A unit of activity of a radionuclide, equal to one Becquerel nuclear disintegration or other nuclear transition from a particular energy state occurring in an amount of a radionuclide during one second-long time interval.(NCI)

C71165 Bq/L Becquerel per A unit of volumetric radioactivity concentration Becquerel per Liter Liter defined as a concentration of a radionuclide with an activity equal to one Becquerel per unit volume equal to one liter.(NCI)

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 398 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C71620 - UNIT - Unit Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C70522 Bq/g Becquerel per A unit of specific radioactivity (massic activity) equal Becquerel per Gram Gram to activity of one Becquerel of the sample with total mass of one gram.(NCI)

C70521 Bq/kg Becquerel per A unit of specific radioactivity (massic activity) equal Becquerel per Kilogram Kilogram to activity of one Becquerel of the sample with total mass of one kilogram.(NCI)

C71167 Bq/mL Becquerel per A unit of volumetric radioactivity concentration Becquerel per Milliliter Milliliter; kBq/L; defined as a concentration of a radionuclide with an Kilobecquerel activity equal to one Becquerel per unit volume equal per Liter to one milliliter or one kilobecquerel per liter.(NCI)

C70524 Bq/mg Becquerel per A unit of specific radioactivity (massic activity) equal Becquerel per Milligram Milligram; to activity of one Becquerel of the sample with total kBq/g; mass of one milligram.(NCI) Kilobecquerel per Gram

C71166 Bq/uL Becquerel per A unit of volumetric radioactivity concentration Becquerel per Microliter Microliter; defined as a concentration of a radionuclide with an kBq/mL; activity equal to one Becquerel per unit volume equal Kilobecquerel to one millionth of a liter.(NCI) per Milliliter; MBq/L; Megabecquerel per Liter

C70523 Bq/ug Becquerel per A unit of specific radioactivity (massic activity) equal Becquerel per Microgram Microgram; to activity of one Becquerel of the sample with total kBq/mg; mass of one microgram.(NCI) Kilobecquerel per Milligram; MBq/g; Megabecquerel per Gram; Bq/mcg

C42559 C Degree Celsius A unit of temperature, named after the Swedish Degree Celsius astronomer Anders Celsius, who first proposed the temperature scale designed so that the freezing point of water is 0 degrees and the boiling point is 100 degrees at standard atmospheric pressure. The current official definition of the Celsius sets 0.01 C to be at the triple point of water and a degree to be 1/273.16 of the difference in temperature between the triple point of water and absolute zero. One degree Celsius represents the same temperature difference as one Kelvin.(NCI)

C48479 CAN Can Dosing Unit A dosing measurement based on the can unit.(NCI) Can Dosing Unit

C48480 CAPSULE Capsule Dosing A dosing measurement based on the capsule unit.(NCI) Capsule Dosing Unit Unit; cap

C48481 CARTRIDGE Cartridge Dosing A dosing measurement based on the cartridge Cartridge Dosing Unit Unit unit.(NCI)

C70534 CCID 50 50 Percent Cell A potency unit defined as a minimal dose of infectious 50 Percent Cell Culture Infective Culture Infective material at which preparation causes cytopathic effects Dose Dose (changes in the morphology and metabolism of cell culture cells, indicating cell death, due to suspected infection) in the 50% of the cell culture-containing vessels inoculated with that dilution of infectious material.(NCI)

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 399 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C71620 - UNIT - Unit Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C70535 CCID 50/dose 50 Percent Cell A potency unit equal to the potency at which one dose 50 Percent Cell Culture Infective Culture Infective of preparation contains one 50 percent cell culture Dose per Dose Dose per Dose infective dose.(NCI)

C68898 CFU/g Colony Forming A unit of measurement of viable bacterial organisms in Colony Forming Unit per Gram Unit per Gram a unit mass of substance of interest defined as the number of colony forming units in one gram of substance.(NCI)

C68902 CFU/mL Colony Forming A unit of measurement of viable bacterial organisms in Colony Forming Unit per Milliliter Unit per a unit volume of substance of interest defined as the Milliliter number of colony forming units in one milliliter of substance.(NCI)

C48483 COAT Coat Dosing Unit A dosing measurement based on the coat unit.(NCI) Coat Dosing Unit

C48484 CONTAINER Container A dosing measurement based on the container Container Dosing Unit Dosing Unit unit.(NCI)

C54703 CUP Cup Dosing Unit A dosing measurement based on the cup unit.(NCI) Cup Dosing Unit

C48489 CYLINDER Cylinder Dosing A dosing measurement based on the cylinder Cylinder Dosing Unit Unit unit.(NCI)

C48466 Ci Curie A unit of radioactivity defined as 3.7 E10 atomic Curie disintegrations or other nuclear transformations per second. One Curie is equal to 37 gigabecquerels.(NCI)

C71170 Ci/L Curie per Liter; A unit of volumetric radioactivity concentration Curie per Liter uCi/uL; defined as a concentration of a radionuclide with an Microcurie per activity equal to one Curie per unit volume equal to Microliter one liter.(NCI)

C70528 Ci/g Curie per Gram; A unit of specific radioactivity (massic activity) equal Curie per Gram uCi/ug; to activity of one Curie of the sample with total mass Microcurie per of one gram.(NCI) Microgram; mCi/mg; Millicurie per Milligram

C70529 Ci/kg Curie per A unit of specific radioactivity (massic activity) equal Curie per Kilogram Kilogram; to activity of one Curie of the sample with total mass uCi/mg; of one kilogram.(NCI) Microcurie per Milligram; mCi/g; Millicurie per Gram

C71172 Ci/mL Curie per A unit of volumetric radioactivity concentration Curie per Milliliter Milliliter defined as a concentration of a radionuclide with an activity equal to one Curie per unit volume equal to one milliliter.(NCI)

C70531 Ci/mg Curie per A unit of specific radioactivity (massic activity) equal Curie per Milligram Milligram; to activity of one Curie of the sample with total mass mCi/ug; of one milligram.(NCI) Millicurie per Microgram

C71171 Ci/uL Curie per A unit of volumetric radioactivity concentration Curie per Microliter Microliter; defined as a concentration of a radionuclide with an Ci/mcL activity equal to one Curie per unit volume equal to one millionth of a liter.(NCI)

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 400 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C71620 - UNIT - Unit Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C70530 Ci/ug Curie per A unit of specific radioactivity (massic activity) equal Curie per Microgram Microgram; to activity of one Curie of the sample with total mass Ci/mcg of one microgram.(NCI)

C42550 Coulomb Coulomb A unit of quantity of electricity, equal to the quantity Coulomb of charge transferred in one second across a conductor in which there is a constant current of one Ampere.(NCI)

C25301 DAYS Day The time for Earth to make a complete rotation on its Day axis; ordinarily divided into twenty-four hours. This also refers to a specific day. (NCI)

C70501 DAgU D Antigen Unit A unit of potency of poliovirus vaccine used for D Antigen Unit poliomyelitis prevention. The unit is poliovirus type-specific.(NCI)

C70502 DAgU/mL D Antigen Unit A unit of potency of poliovirus vaccine expressed as a D Antigen Unit per Milliliter per Milliliter number of D antigen units per one milliliter of vaccine formulation.(NCI)

C100899 DIOPTER Diopter A unit of measurement of the optical power of a Diopter curved mirror or lens represented by the inverse of the focal length in meters.

C48490 DISK Disk Dosing Unit A dosing measurement based on the disk unit.(NCI) Disk Dosing Unit

C98719 DNA copies/mL DNA Copies per The unit of concentration of deoxyribonucleic acid DNA Copies per Milliliter Milliliter (DNA) copies expressed as a number of copies in unit volume equal to one milliliter.

C48492 DRUM Drum Dosing A dosing measurement based on the drum unit.(NCI) Drum Dosing Unit Unit

C70532 EID 50 50 Percent Amount of infectious agent or biological product that 50 Percent Embryo Infective Dose Embryo Infective causes infection in the 50% of embryos such as Dose chicken embryos used in the product potency assay or pathogen activity assay.(NCI)

C70533 EID 50/dose 50 Percent A potency unit for measuring infectious activity of a 50 Percent Embryo Infective Dose Embryo Infective biologic product or an infectious agent preparation per Dose Dose per Dose equal to the potency at which one dose of infectious material contains one 50 percent embryo infective dose.(NCI)

C68875 ELISA unit Enzyme-Linked A unit for measuring concentration or/and reactivity of Enzyme-Linked Immunosorbent Immunosorbent a test substance (an antigen or antibody of interest) as Assay Unit Assay Unit defined in the literature reference standard for the particular quantitative enzyme-linked immunosorbent assay method. The enzyme-linked immunosorbent assay unit is used to express potency of immunologically active substances and products, e.g. vaccines.(NCI)

C68876 ELISA unit/dose Enzyme-Linked A unit for measuring potency of immunologically Enzyme-Linked Immunosorbent Immunosorbent active substance in a product determined as reactivity Assay Unit per Dose Assay Unit per in a quantitative immunoassay for particular antigen or Dose antibody and expressed per quantity of preparation used as a single dose.(NCI)

C68877 ELISA unit/mL Enzyme-Linked A unit for measuring potency of immunologically Enzyme-Linked Immunosorbent Immunosorbent active substance in a product determined as reactivity Assay Unit per Milliliter Assay Unit per in a quantitative immunoassay for particular antigen or Milliliter antibody and expressed per unit volume equal to one milliliter.(NCI)

C96599 EU Ehrlich Units A unit of measure equal to one milligram of Ehrlich Unit urobilinogen per deciliter.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 401 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C71620 - UNIT - Unit Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C44277 F Degree The Fahrenheit temperature scale is named after the Degree Fahrenheit Fahrenheit German physicist Gabriel Fahrenheit (1686-1736), who proposed it in 1724. In this scale, the freezing point of water is 32 degrees Fahrenheit and the boiling point is 212 degrees, placing the boiling and melting points of water 180 degrees apart. In this scale a degree Fahrenheit is 5/9ths of a Kelvin (or of a degree Celsius), and minus 40 degrees Fahrenheit is equal to minus 40 degrees Celsius. (NCI)

C96649 FEU Fibrinogen A unit of measure for the concentration of fibrin Fibrinogen Equivalent Unit Equivalent Units degradation products in a sample, calculated based upon the mass of fibrinogen contained within that sample.

C71321 FINGERTIP UNIT Fingertip Unit An arbitrary dosing unit used predominantly for Fingertip Dosing Unit semisolid topical formulations such as cream, ointment, paste, etc. One fingertip unit is the amount of a product that is squeezed out from a standard tube with 5-millimeter diameter nozzle along an adult's fingertip. A fingertip length is defined from the tip of the index finger to the first finger crease. A fingertip dosing unit varies with age and size of the body. The average fingertip unit is equal to approximately 0.5 gram for an adult male and 0.4 gram for an adult female.(NCI)

C42552 Farad Farad A unit of capacitance equal to the capacitance of a Farad capacitor having an equal and opposite charge of one coulomb on each plate and a potential difference of one volt between the plates.(NCI)

C70513 GBq Gigabecquerel A unit of radioactivity equal to one billion nuclear Gigabecquerel disintegrations or other nuclear transformations per second, or to 10E9 Becquerels.(NCI)

C70525 GBq/g Gigabecquerel A unit of specific radioactivity (massic activity) equal Gigabecquerel per Gram per Gram; to activity of one gigabecquerel of the sample with kBq/ug; total mass of one gram.(NCI) Kilobecquerel per Microgram

C70527 GBq/mg Gigabecquerel A unit of specific radioactivity (massic activity) equal Gigabecquerel per Milligram per Milligram; to activity of one gigabecquerel of the sample with Megabecquerel total mass of one milligram.(NCI) per Microgram; MBq/mcg; MBq/ug

C70526 GBq/ug Gigabecquerel A unit of specific radioactivity (massic activity) equal Gigabecquerel per Microgram per microgram; to activity of one gigabecquerel of the sample with MBq/ng; total mass of one microgram.(NCI) Megabecquerel per nanogram; GBq/mcg

C68915 Gauss Gauss The unit of magnetic flux density. A field of one Gauss Gauss exerts a force on a conductor, placed in the field of 0.1 dyne per Ampere of current per centimeter of conductor. One Gauss represents a magnetic flux of one Maxwell per square centimeter of cross-section perpendicular to the field. One Gauss equals 10-4 Tesla.(NCI)

C18063 Gy Gray A unit of absorbed radiation dose. One gray is equal to Gray an absorbed dose of one joule per kilogram of matter, or to 100 rads.(NCI)

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 402 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C71620 - UNIT - Unit Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C48498 HOMEOPATHIC DILUTION Homeopathic A dosing measurement based on the homeopathic Homeopathic Dilution Unit Dilution Unit dilution unit.(NCI)

C25529 HOURS Hour; hr A unit measure of time equal to 3,600 seconds or 60 Hour minutes. It is approximately 1/24 of a median day. (NCI)

C67274 HPF High Power The area visible under the maximum magnification High Power Field Field power of the objective being used in microscopy.(NCI)

C42558 Henry Henry A unit of electric inductance. A coil with an inductance Henry of one Henry requires a flux of one Weber for each Ampere of induced current. If it is the current which changes, then the induced field will generate a potential difference within the coil: if the inductance is one Henry a current change of one Ampere per second generates a potential difference of one volt. The Henry is a large unit; inductances in practical circuits are measured in millihenrys or microhenrys.(NCI)

C42545 Hz Hertz A unit of frequency equal to one cycle per Hertz second.(NCI)

C48499 IMPLANT Implant Dosing A dosing measurement based on the implant unit.(NCI) Implant Dosing Unit Unit

C48500 IN Inch A traditional unit of length equal to 2.54 centimeters. Inch (NCI)

C48501 INHALATION Inhalation A dosing measurement based on the inhalation Inhalation Dosing Unit Dosing Unit unit.(NCI)

C48579 IU International The unitage assigned by the WHO (World Health International Unit Unit Organization) to International Biological Standards - substances, classed as biological according to the criteria provided by WHO Expert Committee on Biological Standardization (e.g. hormones, enzymes, and vaccines), to enable the results of biological and immunological assay procedures to be expressed in the same way throughout the world. The definition of an international unit is generally arbitrary and technical, and has to be officially approved by the International Conference for Unification of Formulae.(NCI)

C67376 IU/L International Unit of arbitrary substance concentration (biologic International Unit per Liter Unit per Liter; activity concentration) defined as the concentration of IU/L; mIU/mL one international unit per one liter of system volume.(NCI)

C70493 IU/g International A unit of measure of quantity of substance per unit International Unit per Gram Unit per Gram mass, expressed in terms of the International Unit per grams.(NCI)

C67379 IU/kg International An arbitrary unit of substance content expressed in International Unit per Kilogram Unit per international units of biological activity per one Kilogram kilogram of mass of the system. It is also used as a dose calculation unit expressed in international units of biological activity per one kilogram of body mass.(NCI)

C71209 IU/kg/h International A dose calculation unit equal to one international unit International Unit per Kilogram per units per (an arbitrary unit of biological activity) of a product Hour Kilogram per per one kilogram of body mass administered per unit Hour of time equal to one hour.(NCI)

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 403 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C71620 - UNIT - Unit Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C67377 IU/mL International Unit of arbitrary substance concentration (biologic International Unit per Milliliter Unit per activity concentration) defined as the concentration of Milliliter; kIU/L; one international unit per one milliliter of system Kilo volume.(NCI) International Unit per Liter

C67380 IU/mg International Unit of arbitrary substance concentration (biologic International Unit per Milligram Unit per activity concentration) defined as the concentration of Milligram one international unit per one milligram of substance.(NCI)

C48502 JAR Jar Dosing Unit A dosing measurement based on the jar unit.(NCI) Jar Dosing Unit

C42548 Joule Joule A unit of electrical, mechanical, and thermal energy Joule (as well as work and quantity of heat), equal to the work done when the point of application of a force of one Newton is displaced through a distance of one meter in the direction of the force or the work done when a current of one Ampere passes through a resistance of one ohm for one second. One joule is equal to 0.23889 gram-calorie (mean).(NCI)

C48503 KALLIKREIN INHIBITOR Kallikrein A dosing measurement based on the Kallikrein Kallikrein Inhibitor Unit UNIT Inhibitor Unit inhibitor unit.(NCI)

C48504 KIT Kit Dosing Unit A dosing measurement based on the kit unit.(NCI) Kit Dosing Unit

C48505 L Liter A unit of volume equal to a cubic decimeter, or one Liter thousandth of cubic meter, or 1000 cubic centimeters, or approximately 61.023 744 cubic inches.(NCI)

C69160 L/h Liters per hour. Liter per Hour

C73725 L/kg Liter per A dose calculation unit expressed in liter(s) per L/kg Kilogram kilogram. (NCI)

C67388 L/min Liters per A unit of volumetric flow rate defined as the rate at Liter per Minute Minute which one liter of matter travels during the period of time equal to one minute.(NCI)

C67390 L/s L/sec Liters per second. Liter per second

C48531 LB Pound A traditional unit of mass. By international agreement, Pound one avoirdupois pound is equal to exactly 0.453 592 37 kilogram, 16 ounces, or 1.215 28 troy pounds. (NCI)

C48506 LOZENGE Lozenge Dosing A dosing measurement based on the lozenge unit.(NCI) Lozenge Dosing Unit Unit

C67307 LPF Low Power Field The area visible in one view field of the microscope Low Power Field under the low magnification of the objective being used in microscopy.(NCI)

C68878 Log10 ELISA unit Log10 A logarithmic-scale (base 10) unit for measuring Log10 Enzyme-Linked Enzyme-Linked concentration and/or reactivity of a test substance (an Immunosorbent Assay Unit Immunosorbent antigen or antibody of interest) as defined in the Assay Unit literature reference for the particular quantitative enzyme-linked immunosorbent assay method.(NCI)

C68879 Log10 ELISA unit/dose Log10 A logarithmic-scale (base 10) unit for measuring Log10 Enzyme-Linked Enzyme-Linked potency of immunologically active substance in a Immunosorbent Assay Unit per Dose Immunosorbent product determined as reactivity in a quantitative Assay Unit per immunoassay for particular antigen or antibody and Dose expressed per quantity of preparation used as a single dose.(NCI)

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 404 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C71620 - UNIT - Unit Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C70512 MBq Megabecquerel A unit of radioactivity equal to one million nuclear Megabecquerel disintegrations or other nuclear transformations per second, or to 10E6 Becquerels.(NCI)

C71169 MBq/uL Megabecquerel A unit of volumetric radioactivity concentration Megabecquerel per Microliter per Microliter; defined as a concentration of a radionuclide with an GBq/mL; activity equal to one million Becquerels per unit Gigabecquerel volume equal to one millionth of a liter.(NCI) per Milliliter

C96691 MESF Molecules of A unit of measure of the fluorescence intensity of a Molecule of Equivalent Soluble Equivalent fluorochrome-labeled sample, which is equivalent to Fluorochrome Soluble the fluorescence intensity of a solution containing an Fluorochromes equivalent number of molecules of free fluorochrome in solution, under identical experimental conditions.

C96687 MFI Median A unit of measure equal to the geometric mean Median Fluorescence Intensity Fluorescence fluorescence intensity of a log-normal distribution of Intensity fluorescence signals.

C67314 MHz Megahertz The SI derived unit of frequency; equal to one million MHz oscillations per second or to 10E6 hertz. (NCI)

C29846 MONTHS Month One of the 12 divisions of a year as determined by a Month calendar. It corresponds to the unit of time of approximately to one cycle of the moon's phases, about 30 days or 4 weeks. (NCI)

C71183 Mile International A unit of distance equal to 5280 international feet, Mile Mile 1760 international yards, or 1609.344 meters.(NCI)

C71204 NEBULE Nebule A unit of measurement based on the nebule dosing Nebule Dosing Unit unit.(NCI)

C42546 Newton Newton A unit of force which, when applied in a vacuum to a Newton body having a mass of one kilogram, causes an acceleration of one meter per second squared. It is equal to 10E5 dynes.(NCI)

C62653 PACK A number of individual items packaged as a unit. Pack

C48520 PACKAGE Package Dosing A dosing measurement based on the package Package Dosing Unit Unit; Pack unit.(NCI) Dosing Unit

C48521 PACKET Packet Dosing A dosing measurement based on the packet unit.(NCI) Packet Dosing Unit Unit

C48524 PATCH Patch Dosing A dosing measurement based on the patch unit.(NCI) Patch Dosing Unit Unit

C48525 PELLET Pellet Dosing A dosing measurement based on the pellet unit.(NCI) Pellet Dosing Unit Unit

C67264 PFU Plaque Forming A measure of viable infectious entities (e.g. viral Plaque Forming Unit Unit particle or group of particles) in the specimen or product defined as the smallest quantity that can produce a cytopathic effect in the host cell culture challenged with the defined inoculum, visible under the microscope or/and to the naked eye as a plaque. A number of plaque forming units (PFU) per unit volume is a conventional way to refer the titer of an infective entity in a specimen or preparation.(NCI)

C71198 PFU/dose Plaque Forming A unit of potency of a biological product expressed as Plaque Forming Unit per Dose Unit per Dose a quantity of viable infectious entities capable to produce a cytopathic effect in the appropriate cell culture per a single dose of the preparation.(NCI)

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 405 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C71620 - UNIT - Unit Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C71199 PFU/mL Plaque Forming A unit of potency of a biological product expressed as Plaque Forming Unit per Milliliter Unit per a quantity of viable infectious entities capable to Milliliter produce a cytopathic effect in the appropriate cell culture per one milliliter of the preparation.(NCI)

C48530 POUCH Pouch Dosing A dosing measurement based on the pouch unit.(NCI) Pouch Dosing Unit Unit

C48532 PRESSOR UNITS Pressor Unit A dosing measurement based on the pressor unit.(NCI) Pressor Unit

C65060 PUFF Puff A means of delivering a defined dose of a therapeutic Puff Dosing Unit aerolized solution into either the upper or lower respiratory tract. Metered-dose inhalers or spray pumps are devices that provide a puff dose for delivery into either the oral or the nasal cavity.(NCI)

C42547 Pa Pascal A unit of pressure equivalent to one Newton per square Pascal meter or 10 bars or to 1.45x10(E-4) pounds per square inch.(NCI)

C73993 Pack Year A quantification of lifetime tobacco exposure defined Pack Year as (number of cigarettes smoked per day x number of years smoked)/20. One pack-year is smoking 20 cigarettes a day for one year.

C48590 QUANTITY SUFFICIENT Quantity A quantity of an ingredient or product needed to bring Quantity Sufficient Sufficient up a volume or weight of the preparation to a final amount as it is indicated in the prescription; also refers to a determination of an adequate supply of medicine to fulfill either a prescribed amount or a sufficient quantity to provide treatment over a specified time frame.(NCI)

C44256 RATIO A unit of measurement for the quotient of the amount Ratio of one entity to another.

C62609 RING Ring Dosing Unit A dosing measurement based on the ring unit.(NCI) Ring Dosing Unit

C67441 RNA copies/mL RNA Copies per The unit of concentration of Ribonucleic Acid (RNA) RNA Copy per Milliliter Milliliter copies expressed as a number of copies in unit volume equal to one milliliter.(NCI)

C18064 Rad Rad The special unit for absorbed radiation dose, which is Rad the amount of energy from any type of ionizing radiation (e.g., alpha, beta, gamma, neutrons, etc.) deposited in any medium (e.g., water, tissue, air). A dose of one rad means the absorption of 100 ergs per gram of absorbing tissue. One rad is equal to 0.01 gray.(NCI)

C70575 Roentgen Roentgen A unit of exposure to ionizing radiation. One Roentgen Roentgen is the amount of gamma or x-rays required to produce ions resulting in a charge of 2.58E-4 Coulombs/kilogram of air under standard conditions.(NCI)

C71324 SACHET Sachet dosing A dosing unit that contains a solid pharmaceutical Sachet Dosing Unit unit preparation in the form of a small packet or bag made from a flexible, often porous material.(NCI)

C48536 SCOOPFUL Scoopful Dosing A dosing measurement based on the scoopful Scoopful Dosing Unit Unit unit.(NCI)

C48537 SPRAY Spray Dosing A dosing measurement based on the spray unit.(NCI) Spray Dosing Unit Unit

C48538 STRIP Strip Dosing A dosing measurement based on the strip unit.(NCI) Strip Dosing Unit Unit

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 406 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C71620 - UNIT - Unit Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C48539 SUPPOSITORY Suppository A dosing measurement based on the suppository Suppository Dosing Unit Dosing Unit unit.(NCI)

C48540 SYRINGE Syringe Dosing A dosing measurement based on the syringe unit.(NCI) Syringe Dosing Unit Unit

C42555 Siemens Siemens A unit of electrical conductance, admittance, and Siemens susceptance. A conductor has a conductance of one Siemens if an electrical potential difference of one volt produces a one Ampere current in it. The conductance in Siemens is the reciprocal of its resistance in ohms.(NCI)

C42553 Sv Sievert A unit of equivalent radiation dose. One Sv is received Sievert when the actual absorbed dose of ionizing radiation, after being multiplied by the dimensionless factors Q (the relative biological efficiency or quality factor) and N (the product of any other multiplying factors that takes into account the distribution of energy throughout the dose), is one joule per kilogram. In this scheme, the relationship between the absorbed dose of radiation D and the dose equivalent H is, therefore, given by H = QND. Both Q and N are stipulated by the International Commission on Radiological Protection. One Sv is equal to 100 rem.(NCI)

C48542 TABLET Tablet Dosing A dosing measurement based on the tablet unit.(NCI) Tablet Dosing Unit Unit; tab

C48543 TAMPON Tampon Dosing A dosing measurement based on the tampon unit.(NCI) Tampon Dosing Unit Unit

C70537 TCID 50/dose 50 Percent A potency unit equal to the potency at which one dose 50 Percent Tissue Culture Infective Tissue Culture of preparation contains one 50 percent tissue culture Dose per Dose Infective Dose infective dose.(NCI) per Dose

C48547 TRACE Trace Dosing An extremely small amount.(NCI) Trace Dosing Unit Unit

C48548 TROCHE Troche Dosing A dosing measurement based on the troche unit.(NCI) Troche Dosing Unit Unit

C48549 TUBE Tube Dosing A dosing measurement based on the tube unit.(NCI) Tube Dosing Unit Unit

C48541 Tbsp Tablespoon A unit of volume informally used in pharmacy. The Tablespoon Dosing Unit Dosing Unit tablespoon has been standardized at 15 milliliters in US, Britain, Canada, and New Zealand, and at 20 milliliters in Australia and some European countries.(NCI)

C42557 Tesla Tesla A unit of magnetic flux density equal to the magnitude Tesla of the magnetic field vector necessary to produce a force of one Newton on a charge of one coulomb moving perpendicular to the direction of the magnetic field vector with a velocity of one meter per second. It is equivalent to one Weber per square meter.(NCI)

C44278 U Unit A single undivided thing occurring in the composition U of something else.

C67456 U/L mU/mL; Unit per An arbitrary unit of substance concentration equal to Unit per Liter Liter the concentration at which one liter of mixture contains one unit of a substance. (NCI)

C73773 U/animal Unit per Animal An arbitrary dosing unit expressed in unit(s) per U/animal animal. (NCI)

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 407 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C71620 - UNIT - Unit Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C77606 U/g Unit per Gram An arbitrary unit of substance content expressed in Unit per Gram unit(s) per gram. (NCI)

C73774 U/g/day Unit per Gram An arbitrary unit of substance rate expressed in unit(s) U/g/day per Day per gram per period of time equal to twenty-four hours. (NCI)

C73775 U/g/h Unit per Gram An arbitrary unit of substance rate expressed in unit(s) U/g/h per Hour per gram per period of time equal to sixty minutes. (NCI)

C73776 U/g/min Unit per Gram An arbitrary unit of substance rate expressed in unit(s) U/g/min per Minute per gram per period of time equal to sixty seconds. (NCI)

C67465 U/kg Unit per An arbitrary unit of substance content expressed in Unit per Kilogram Kilogram units of biological activity per unit of mass equal to one kilogram. Unit per kilogram is also used as a dose calculation unit expressed in arbitrary units per one kilogram of body mass. (NCI)

C73777 U/kg/day Unit per An arbitrary unit of substance rate expressed in unit(s) U/kg/day kilogram per Day per gram per period of time equal to twenty-four hours. (NCI)

C73778 U/kg/h Unit per An arbitrary unit of substance rate expressed in unit(s) U/kg/h Kilogram per per gram per period of time equal to sixty minutes. Hour (NCI)

C73779 U/kg/min Unit per An arbitrary unit of substance rate expressed in unit(s) U/kg/min Kilogram per per gram per period of time equal to sixty seconds. Minute (NCI)

C67467 U/m2 Unit per Square A unit expressed as a number of arbitrary units of U/m2 Meter substance per one square meter of a body surface area.

C73783 U/m2/day Unit per Square An arbitrary unit of substance rate expressed in unit(s) U/m2/day Meter per Day per square meter per period of time equal to twenty-four hours. (NCI)

C73784 U/m2/h Unit per Square An arbitrary unit of substance rate expressed in unit(s) U/m2/h Meter per Hour per square meter per period of time equal to sixty minutes. (NCI)

C73785 U/m2/min Unit per Square An arbitrary unit of substance rate expressed in unit(s) U/m2/min Meter per per square meter per period of time equal to sixty Minute seconds. (NCI)

C77607 U/mL Unit per An arbitrary unit of substance content expressed in Unit per Milliliter Milliliter unit(s) per milliliter. (NCI)

C73780 U/mg Unit per An arbitrary unit of substance content expressed in Unit per Milligram Milligram unit(s) per milligram. (NCI)

C92618 U/mmol Unit per An arbitrary unit of substance concentration equal to U/mmol Millimole the concentration at which one millimole of a mixture contains one unit of a substance. (NCI)

C42551 V Volt A unit of electric potential and electromotive force, Volt equal to the difference of electric potential between two points on a conducting wire carrying a constant current of one Ampere when the power dissipated between the points is one watt. This is equivalent to the potential difference across a resistance of one ohm when one Ampere of current flows through it.(NCI)

C48551 VIAL Vial Dosing Unit A dosing measurement based on the vial unit.(NCI) Vial Dosing Unit

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 408 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C71620 - UNIT - Unit Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C48552 WAFER Wafer Dosing A dosing measurement based on the wafer unit.(NCI) Wafer Dosing Unit Unit

C29844 WEEKS Week Any period of seven consecutive days. (NCI) Week

C42549 Watt Watt A unit of power equal to the power which in one Watt second produces or transfers the energy of one joule. The unit is used in measurements of power emitted, transferred or received as radiation, sound waves, heat flow rate, and rate of energy transfer. Equal to 1/746 of horsepower.(NCI)

C42556 Weber Weber A unit of magnetic flux, equal to the flux that produces Weber in a circuit of one turn an electromotive force of one volt, when the flux is uniformly reduced to zero within one second.(NCI)

C29848 YEARS Year The period of time that it takes for earth to make a Year complete revolution around the sun, approximately 365 days; a specific one year period.(NCI)

C64553 ag Attogram A unit of mass equal to one quintillionth of a gram Attogram (10E-18 gram).(NCI)

C68855 amol Attomole A unit of amount of substance equal to one Attomole quintillionth of a mole (10E-18 mole).(NCI)

C42536 amp Ampere A unit of electric current, named after the French Ampere physicist Andre Ampere. It is that constant current which, if maintained in two straight parallel conductors of infinite length and zero diameter separated by one meter in a vacuum, would produce between these conductors a force equal to 2(10E7) Newton per meter of length. This is dependent upon the definitions of the meter, kilogram, and second. One Ampere represents 6.24 x 10(E18) unit electric charge carriers, such as electrons, passing a specified fixed point in one second.(NCI)

C64559 amu Atomic Mass A small unit of mass used to express atomic and amu Unit molecular masses. (NCI)

C70497 anti-Xa IU Anti-Xa Activity A unit of unfractionated or low molecular weight Anti-Xa Activity International Unit International heparin anticoagulation potency determined as the Unit amount that neutralizes one unit of coagulation factor Xa preparation defined as an international biological standard by WHO (World Health Organization) First International Low Molecular Weight Heparin Reference Standard.(NCI)

C70498 anti-Xa IU/mL Anti-Xa Activity A specific anticoagulation activity of unfractionated or Anti-Xa Activity International Unit International low molecular weight heparin on factor Xa, expressed per Milliliter Unit per as a number of international anti-Xa heparin units per Milliliter one milliliter of plasma.(NCI)

C54711 atm Atmosphere A unit of pressure, equal to a barometer reading of 760 Atmosphere mm Hg. 1 atmosphere is 101325 Pascals and 1.01325 bar. This unit of pressure is roughly equal to the average atmospheric pressure at sea level on the earth.(NCI)

C71200 bel Bel A logarithmic ratio unit (base-10 logarithms) used to Bel express relative magnitude of a physical quantity (usually power or intensity) in comparison with a specified or implied reference level. Particularly, Bel is used as a unit of relative sound intensity. In the latter context it is equal to ten decibels or to approximately 1.151293 nepers.(NCI)

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 409 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C71620 - UNIT - Unit Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C67193 cal Calorie A measurement of nutritional energy. The quantity of calorie thermal energy required to raise one gram of water one degree Centigrade under standard conditions. 1 calorie equals 4.186 joules. (NCI)

C42538 cd Candela The candela is the basic unit of luminous intensity. It is Candela the luminous intensity in a given direction of a small monochromatic light source at 540 terahertz emitting 1/683 watt per steradian in that direction. This is dependent upon the definitions of the meter, kilogram, and second.(NCI)

C64554 cg Centigram A unit of mass equal to one hundredth of a gram.(NCI) Centigram

C49668 cm Centimeter A basic unit of length equal to one hundredth of a Centimeter meter or approximately 0.393 700 787 inch. (NCI)

C91060 cm H2O A unit of pressure defined by a column of water with a Centimeters of Water height of one centimeter, frequently used to measure central venous pressure, intracranial pressure, and for pressures during mechanical ventilation.

C48460 cm2 Square A unit of area measurement equal to a square Square Centimeter Centimeter measuring one centimeter on each side. One square centimeter is equal to 10E-4 square meter.(NCI)

C68687 cmol Centimole A unit of amount of substance equal to one hundredth Centimole of a mole (10E-2 mole).(NCI)

C100900 copies/mL A unit of concentration expressed as a number of Copies per Milliliter copies per unit volume equal to one milliliter.

C71176 cycle/min Cycle per Minute A unit of frequency equal to the frequency at which Cycle per Minute one complete execution of a periodically repeated phenomenon, alternation, event, or sequence of events occurs per unit of time equal to one minute.(NCI)

C71480 cycle/sec Cycle per A unit of frequency equal to the frequency at which Cycle per Second Second one complete execution of a periodically repeated phenomenon, alternation, event, or sequence of events occurs per unit of time equal to one second.(NCI)

C64697 dL Deciliter The unit of volume equal to one tenth of a liter. dL Accepted for use with the SI. (NCI)

C68667 deg Degree Unit of A unit of plane angle measurement equal to the length Degree Unit of Plane Angle Plane Angle of the arc cut out by the angle, divided by the circumference of the circle, and multiplied by 360. The symbol for degrees is a small superscript circle. One radian is about 57 degrees and one degree is pi/180 radians.(NCI)

C68685 dmol Decimole A unit of amount of substance equal to one tenth of a Decimole mole (10E-1 mole).(NCI)

C64564 dram Dram A unit of mass equal to 1/16 Avoirdupois ounce or Dram Mass Unit 1/256 Avoirdupois pound. One dram equals approximately 1.7718451953125 grams.(NCI)

C70470 dyn Dyne A unit of force defined as the force that accelerates a Dyne mass of one gram at the rate of one centimeter per second squared. One dyne is equal to 10E-5 Newton and 2.248E-6 pounds of force.(NCI)

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 410 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C71620 - UNIT - Unit Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C67273 eq Equivalent A unit of relative amount of a substance that combines Equivalent Weight Weight with or displaces 8.0 grams of oxygen or 1.008 gram of hydrogen. The unit is usually expressed in grams and is equal to the amount of substance that gains or loses one mole of electrons in a redox reaction, or to the amount of substances that releases or accepts one mole of hydrogen ions in a neutralization reaction; or to the amount of electrolyte that carries one mole of positive or negative charge. This is a large unit and measurements are more often done in its derivatives, e.g. in milliequivalents.(NCI)

C64780 fL Femtoliter The unit of volume equal 10E-15 liter. Femtoliter

C64552 fg Femtogram A unit of mass equal to one quadrillionth of a gram Femtogram (10E-15 gram).(NCI)

C68854 fmol Femtomole A unit of amount of substance equal to one Femtomole quadrillionth of a mole (10E-15 mole).(NCI)

C68887 fmol/L Femtomole per A unit of concentration (molarity unit) equal to one fmol/L Liter quadrillionth of a mole (10E-15 mole) of solute in one liter of solution. (NCI)

C73711 fmol/g Femtomole per A molality unit that describes the amount of substance, fmol/g Gram expressed in femtomole(s) per gram. (NCI)

C71253 ft Foot A unit of length defined by the U.S. National Bureau of International Foot Standards as 30.48 centimeters. It is equal to 0.3048 meter, 12 inches, or to approximately 0.999998 survey foot.(NCI)

C48461 ft2 Square Foot A unit of area equal to 144 square inches, 929.0304 Square Foot square centimeters, or 9.290304E-2 square meters.(NCI)

C68859 ft3 Standard Cubic A unit used in physical chemistry to express the Standard Cubic Foot Foot amount of substance of an ideal gas in one cubic foot at 60 degrees Fahrenheit and pressure of one atmosphere.(NCI)

C48155 g Gram A metric unit of mass equal to one one thousandth of a Gram kilogram. (NCI)

C42576 g/L g/L; Gram per A unit of mass concentration defined as the Kilogram per Cubic Meter Liter; kg/m3; concentration of one kilogram of a substance per unit Kilogram per volume of the mixture equal to one cubic meter, or the Cubic Metre; concentration of one milligram of a substance per unit Microgram per volume of the mixture equal to one milliliter, or one Microliter; gram of a substance per one liter of the mixture. It is Milligram per also a unit of mass density (volumic mass) defined as Milliliter; ug/uL; the density of substance which mass equal to one mg/mL milligram occupies the volume one milliliter.(NCI)

C73713 g/animal Gram per Animal A unit of measure expressed in gram(s) per animal. g/animal

C73714 g/animal/day Gram per Animal A unit of measure expressed in gram(s) per animal per g/animal/day per Day period of time equal to twenty-four hours.

C73715 g/animal/wk Gram per Animal A unit of measure expressed in gram(s) per animal per g/animal/week per Week period of time equal to seven days.

C73716 g/cage Gram per Cage A unit of measure expressed in gram(s) per cage. g/cage

C73717 g/cage/day Gram per Cage A unit of measure expressed in gram(s) per cage per g/cage/day per Day period of time equal to twenty-four hours.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 411 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C71620 - UNIT - Unit Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C73718 g/cage/wk Gram per Cage A unit of measure expressed in gram(s) per cage per g/cage/week per Week period of time equal to seven days.

C71201 g/cm2 Gram per Square A unit of area density defined as a spread rate at which Gram per Square Centimeter Centimeter one gram of a substance is spread over the area of one square centimeter. The unit is also used as a dose calculation unit.(NCI)

C64783 g/dL Gram per A unit of mass concentration defined as the Gram per Deciliter Deciliter; g% concentration of one gram of a substance per unit volume of the mixture equal to one deciliter (100 milliliters). The concept also refers to the metric unit of mass density (volumic mass) defined as the density of substance which mass equal to one gram occupies the volume one deciliter.(NCI)

C67372 g/day Gram per Day A dose calculation unit expressed in gram(s) per Gram per 24 Hours period of time equal to twenty-four hours.

C70453 g/g Gram per Gram A unit of a mass fraction expressed as a number of g/g grams of substance per gram of mixture.

C73720 g/g/day Gram per Gram A unit of measure expressed in gram(s) per gram per g/g/day per Day period of time equal to twenty-four hours.

C69104 g/kg Gram per A unit of a mass fraction expressed as a number of Gram per Kilogram Kilogram; mg/g; grams of substance per kilogram of mixture. The unit Milligram per is also used as a dose calculation unit.(NCI) Gram

C66975 g/kg/day Gram per A dose administration rate unit equal to the rate at g/kg/day Kilogram per which one gram of a product per kilogram of body Day mass is delivered or administered over the period of one day. (NCI)

C67282 g/m2 Gram per Square A unit of area density defined as a spread rate at which Gram per Square Meter Meter one gram of a substance is spread over the area of one square meter. It is equal to approximately 0.029 4935 ounce per square yard. Also used as a dose calculation unit.(NCI)

C73722 g/m2/day Gram per Square A dose calculation unit expressed in gram(s) per g/m2/day Meter per Day square meter per period of time equal to twenty-four hours.

C73721 g/mol Gram per Mole A unit of mass commonly used to express the molar g/mol mass of a substance in gram(s) per mole. (NCI)

C48497 grain Grain A unit of mass derived from the weight of a grain and Grain equal to one seven-thousandth of a pound, or 1/480 troy ounce, or 64.79891 milligrams. The original English grain unit based on the mass of a ripe grain barleycorn was larger the corresponding grain units of France and other European nations which were based on the weight of the smaller wheat grain.(NCI)

C69442 gtt Drop A unit of volume equal to 0.05 milliliter (20 Medical Drop drops/ml).(NCI)

C68871 in2 Square Inch A unit of area equal to the area of a square with sides Square Inch of one inch. It is equal to 6.4516 square centimeters.(NCI)

C70511 kBq Kilobecquerel A unit of radioactivity equal to one thousand nuclear Kilobecquerel disintegrations or other nuclear transformations per second, or to 10E3 Becquerels.(NCI)

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 412 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C71620 - UNIT - Unit Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C71168 kBq/uL Kilobecquerel A unit of volumetric radioactivity concentration Kilobecquerel per Microliter per Microliter; defined as a concentration of a radionuclide with an GBq/L; activity equal to one thousand Becquerels per unit Gigabecquerel volume equal to one millionth of a liter.(NCI) per Liter; MBq/mL; Megabecquerel per Milliliter

C70492 kIU Kilo A unit equal to one thousand international units.(NCI) Kilointernational Unit International Unit

C92615 kN/cm2 Kilonewton per The kilonewton per centimeter squared is an SI derived Kilonewton per Centimeter Squared Centimeter unit of pressure; one newton is computed as the force Squared; necessary to accelerate a mass of one gram at the rate kdyn/cm2 of one centimeter per second squared. One kilonewton per centimeter squared is descriptive of the amount of force exerted in a particular area. This measurement is frequently used when describing conditions of cellular movement. (NCI)

C67284 kPa Kilopascal A SI derived unit of pressure equivalent to 1000 kPa newtons per square meter or 10000 bars or to 0.145 pound per square inch. (NCI)

C71202 kUSP Kilo United A unit of potency equal to one thousand US Kilo United States Pharmacopeia States Pharmacopoeia Units.(NCI) Unit Pharmacopoeia Unit

C42566 kat Katal A unit for measuring catalytic (e.g. enzymatic) activity, Katal the ability of the compound to accelerate the chemical reaction by providing a lower energy pathway between the reactants and the products. One katal is that catalytic activity which will raise the rate of reaction by one mole per second in a specified assay system. When the katal is used, the measurand should be specified by reference to the measurement procedure; the measurement procedure must identify the indicator reaction. The katal is not used to express a rate of reaction itself, which should be expressed in moles per second.(NCI)

C67194 kcal Kilogram-Calori A unit of energy defined as the amount of heat required Calorie e to raise the temperature of one kilogram of pure water by one degree Centigrade under standard conditions (the specific heat of the water at 15 degrees Celsius and the constant pressure of 101.325 kilopascals or one atm being defined as unity), equal to approximately 4.1855 kJ. It is also is used by nutritionists in measuring the energy-producing potential of food as a unit of potential energy contained by a substance, which can be liberated when the material is oxidized, usually by combustion in the presence of oxygen.(NCI)

C28252 kg Kilogram The basic SI unit of mass. It is defined as the mass of Kilogram an international prototype in the form of a platinum-iridium cylinder kept at Sevres in France. It is the only basic unit still defined in terms of a material object, and also the only one with a prefix [kilo] already in place. A kilogram is equal to 1,000 grams and 2.204 622 6 pounds. (NCI)

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 413 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C71620 - UNIT - Unit Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C64566 kg/L Kilogram per A unit of mass concentration defined as the Kilogram per Liter Liter; g/mL; concentration of one kilogram of a substance in unit Gram per volume of the mixture equal to one liter. The concept Milliliter; also refers to the unit of mass density (volumic mass) gram/mL; kg/L; defined as the density of substance which mass equal mg/uL to one kilogram occupies the volume one liter.(NCI)

C69094 kg/cm2 Kilogram per A unit of spread rate of a substance by mass expressed Kilogram Per Square Centimeter Square in kilograms per area unit equal to one square Centimeter centimeter, used also as a measure of area density and as a dose calculation unit.(NCI)

C49671 kg/m2 Kilogram per A unit expressed as kilogram of mass per square meter Kilogram Per Square Meter Square Meter of area.(NCI)

C71177 km Kilometer A unit of distance equal to 1000 meters, 0.621 miles, Kilometer 1094 yards, or 3281 feet.(NCI)

C71203 km/h Kilometer Per A unit of both speed (scalar) and velocity (vector), Kilometer per Hour Hour defined as the distance of one thousand meters travelled per unit time equal to one hour.(NCI)

C42560 lm Lumen A unit of luminous flux. It is the amount of light that Lumen falls on a unit area at unit distance from a source of one candela.(NCI)

C70480 log EID 50/dose Log10 50 A logarithmic-scale (base 10) potency unit for Log10 50 Percent Embryo Infective Percent Embryo measuring infectious activity of a biologic product or Dose per Dose Infective Dose infectious agent preparation equal to the potency at per Dose which one dose of infectious material contains one 50 percent embryo infective dose.(NCI)

C70484 log10 CCID 50 Log10 50 A potency unit for measuring infectious activity of a Log10 50 Percent Cell Culture Percent Cell biologic product or infectious agent preparation equal Infective Dose Culture Infective to a base-10 logarithm of amount of product or agent Dose preparation that causes infection in the 50% of the cell culture-containing vessels inoculated with that dilution of infectious material in the product potency assay or pathogen activity assay.(NCI)

C70485 log10 CCID 50/dose Log10 50 A logarithmic-scale (base 10) potency unit for Log10 50 Percent Cell Culture Percent Cell measuring infectious activity of a biologic product or Infective Dose per Dose Culture Infective infectious agent preparation equal to the potency at Dose per Dose which one dose of infectious material contains one 50 percent cell culture infective dose.(NCI)

C70479 log10 EID 50 Log10 50 A potency unit for measuring infectious activity of a Log10 50 Percent Embryo Infective Percent Embryo biologic product or infectious agent equal to a base-10 Dose Infective Dose logarithm of amount of product or agent preparation that causes infection in the 50% of embryos (such as chicken embryos) used in the product potency assay or pathogen activity assay.(NCI)

C70488 log10 TCID 50 Log10 50 A potency unit for measuring infectious activity of a Log10 50 Percent Tissue Culture Percent Tissue biologic product or infectious agent preparation equal Infective Dose Culture Infective to a base-10 logarithm of amount of product or agent Dose preparation that causes infection in the 50% of the tissue culture-containing flasks inoculated with that dilution of infectious material in the product potency assay or pathogen activity assay.(NCI)

C70489 log10 TCID 50/dose Log10 50 A logarithmic-scale (base 10) potency unit for Log10 50 Percent Tissue Culture Percent Tissue measuring infectious activity of a biologic product or Infective Dose per Dose Culture Infective infectious agent preparation equal to the potency at Dose per Dose which one dose of infectious material contains one 50 percent tissue culture infective dose.(NCI)

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 414 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C71620 - UNIT - Unit Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C42561 lx Lux A unit of illuminance equal to the direct illumination Lux on a surface that is everywhere one meter from a uniform point source of one candela; a unit of illuminance that is equal to one lumen per square meter.(NCI)

C41139 m Meter A meter is defined as the length of the path traveled by Meter light in a vacuum during a time interval of 1/299 792 458 of a second and is equal to 1.093 61 yards.(NCI)

C42571 m/sec Meter Per A unit of both speed (scalar) and velocity (vector), Meter Per Second Second defined as the distance of one meter travelled per unit time equal to one second.(NCI)

C42569 m2 Square Meter The SI unit of area measurement equal to a square Square Meter whose sides are one meter long. Square meter is equal to 10,000 square centimeters; 0.01 are; 1.196 square yards; 10.76 square feet; 1550 square inches. (NCI)

C42570 m3 Cubic Meter A unit of volume or capacity equal to the volume of a Cubic Meter cube with edges one meter in length. It is equal to 1,000 liters; 1,000 cubic decimeters; 10(E6) cubic centimeters; 25.3 cubic feet; 6.29 barrels.(NCI)

C48511 mCi Millicurie A unit of radioactivity equal to one thousandth of a Millicurie Curie or 37 megabecquerels, and corresponding to a radioactivity of 37 millions of atomic disintegrations per second.(NCI)

C71174 mCi/L Millicurie per A unit of volumetric radioactivity concentration Millicurie per Liter Liter; uCi/mL; defined as a concentration of a radionuclide with an Microcurie per activity equal to one thousandth of a Curie per unit Milliliter volume equal to one liter.(NCI)

C70570 mCi/kg Millicurie per A unit of specific radioactivity (massic activity) equal Millicurie per Kilogram Kilogram; uCi/g; to activity of one millicurie of the sample with total Microcurie per mass of one kilogram.(NCI) Gram

C48512 mEq Milliequivalent A unit of relative amount of a substance equal to one Milliequivalent thousandth of an equivalent weight.(NCI)

C67474 mEq/L Milliequivalent A concentration unit measured as a number of Milliequivalent per Liter Per Liter; milliequivalents of solute per liter of solution.(NCI) mval/L; Millivalent per Liter

C67473 mEq/dL Milliequivalent A concentration unit measured as a number of mEq/dL per Deciliter milliequivalents of solute per deciliter of solution. (NCI)

C67471 mEq/day Milliequivalents A unit of relative amount of substance flow rate Milliequivalent per 24 Hours per Day equivalent to the rate at which one thousandth of an equivalent of substance travels to a given object or space over a period of time equal to twenty four hours.(NCI)

C70580 mEq/g Milliequivalent A unit of relative amount of substance content Milliequivalent per Gram Per Gram equivalent to the content at which one gram of mixture contains one thousandth of an equivalent of a component. The unit is also used as a dose calculation unit.(NCI)

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 415 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C71620 - UNIT - Unit Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C67475 mEq/kg Milliequivalent A unit of relative amount of substance content Milliequivalent per Kilogram Per Kilogram equivalent to the content at which one kilogram of mixture contains one thousandth of an equivalent of a component. The unit is also used as a dose calculation unit.(NCI)

C73737 mEq/mL Milliequivalent A concentration unit expressed in milliequivalent(s) of mEq/mL per Milliliter solute per milliliter of solution. (NCI)

C92616 mEq/mmol Milliequivalent A concentration unit measured as a number of one Milliequivalent per Milliimole per Millimole thousandth of an equivalent weight per millimole of substance. (NCI)

C70578 mEq/uL Milliequivalent A concentration unit measured as a number of Milliequivalent per Microliter Per Microliter milliequivalents of solute per microliter of solution.(NCI)

C70581 mEq/ug Milliequivalent A unit of relative amount of substance content Milliequivalent per Microgram Per Microgram; equivalent to the content at which one millionth of a mEq/mcg gram of mixture contains one thousandth of an equivalent of a component. The unit is also used as a dose calculation unit.(NCI)

C28254 mL Milliliter; cm3 The unit of volume equal to one thousandth of a liter, Milliliter one cubic centimeter, 10E-6 cubic meter, or approximately to 0.061 023 7 cubic inch.(NCI)

C73746 mL/animal Milliliter per A unit of measure expressed in milliliter(s) per animal. mL/animal Animal

C73747 mL/animal/day Milliliter per A unit of measure expressed in milliliter(s) per animal mL/animal/day Animal per Day per period of time equal to twenty-four hours.

C73748 mL/animal/wk Milliliter per A unit of measure expressed in milliliter(s) per animal mL/animal/week Animal per Week per period of time equal to seven days.

C73749 mL/breath Milliliter per A unit of measure expressed in milliliter(s) per mL/breath Breath inspiration or expiration of breath.

C73750 mL/cage Milliliter per A unit of measure expressed in milliliter(s) per cage. mL/cage Cage

C73751 mL/cage/day Milliliter per A unit of measure expressed in milliliter(s) per cage mL/cage/day Cage per Day per period of time equal to twenty-four hours.

C73752 mL/cage/wk Milliliter per A unit of measure expressed in milliliter(s) per cage mL/cage/week Cage per Week expressed per period of time equal to seven days.

C98755 mL/cm H2O A unit of pressure expressed in milliliter(s) per Milliliter per Centimeter of Water centimeter of water. (NCI)

C73753 mL/day Milliliter per Milliliters per day. mL/day Day

C73754 mL/g Milliliter per A unit of measure expressed in milliliter(s) per gram. mL/g Gram

C73755 mL/g/day Milliliter per Liters per kilogram per day. Milliliter per Gram per Day Gram per Day; mL/g/day; uL/mg/day; L/day/kg; mL/day/g; uL/day/mg; L/kg/d

C73756 mL/g/h Milliliter per Milliliters per gram per hour. mL/g/h Gram per Hour

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 416 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C71620 - UNIT - Unit Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C73757 mL/g/min Milliliter per Milliliters per gram per minute. mL/g/min Gram per Minute

C66962 mL/h Milliliters per A unit of volumetric flow rate defined as the rate at Milliliter per Hour Hour which one milliliter of matter travels during the period of time equal to one hour.(NCI)

C67411 mL/kg Milliliter per A dose calculation unit equal to one milliliter of mL/kg Kilogram preparation per one kilogram of body mass. (NCI)

C73758 mL/kg/day Milliliter per Milliliters per kilogram per day. mL/kg/day Kilogram per Day

C73759 mL/kg/h Milliliter per Milliliters per kilogram per hour. mL/kg/h Kilogram per Hour

C73760 mL/kg/min Milliliter per Milliliters per kilogram per minute. mL/kg/min Kilogram per Minute; uL/g/min; mL/min/kg; uL/min/g; mL/kg/min

C73761 mL/m2 Milliliter per A unit of measure expressed in milliliter(s) per square mL/m2 Square Meter meter.

C66977 mL/m2/day Milliliter per A dose calculation unit expressed in milliliter(s) per mL/m2/day Square Meter per square meter per period of time equal to twenty-four Day hours. (NCI)

C73762 mL/m2/h Milliliter per A dose calculation unit expressed in milliliter(s) per mL/m2/h Square Meter per square meter per period of time equal to sixty minutes. Hour (NCI)

C73763 mL/m2/min Milliliter per A dose calculation unit expressed in milliliter(s) per mL/m2/min Square Meter per square meter per period of time equal to sixty seconds. Minute (NCI)

C64777 mL/min Milliliters per A metric unit of volumetric flow rate defined as the Milliliter per Minute Minute rate at which one milliliter of matter travels during the period of time equal to one minute.(NCI)

C67412 mL/min/1.73m2 A metric unit of volumetric flow rate defined as the Milliliter per Minute per 1.73 m2 of rate at which one milliliter of matter travels during the Body Surface Area period of time equal to one minute per 1.73 meters squared of body surface area.

C67318 mOsm Milliosmole A unit of osmotic pressure equal to one thousandth of mOsm an osmole or osmotic pressure of 0.001 molar solution of a substance that does not dissociate. (NCI)

C67427 mOsm/kg Milliosmole per A unit of osmotic pressure equal to one thousandth of mOsm/kg Kilogram an osmole per kilogram substance.

C73765 mPa Millipascal A SI derived unit of pressure equivalent to one mPa thousandth of one pascal. (NCI)

C67408 mU/L An arbitrary unit of substance concentration equal to Microunit per Milliliter the concentration at which one liter of mixture contains one thousandth of a unit of a substance.

C67324 mV Millivolt A unit of electric potential and electromotive force Millivolt equal to one thousandth of a volt.(NCI)

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 417 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C71620 - UNIT - Unit Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C28253 mg Milligram The unit of mass equal to one thousandth of a gram or Milligram 1000 micrograms. One milligram equals approximately 0.015432 grain or 35.274 x 10E-6 ounce.(NCI)

C64572 mg/L g/m3; Gram per A unit of mass concentration equal to the Microgram per Milliliter Cubic Meter; concentration of one gram of a substance per unit mg/L; volume of the mixture equal to one cubic meter. The Microgram per concept also refers to the metric unit of mass density Milliliter; (volumic mass) defined as the density of substance Milligram per which mass equal to one gram occupies the volume Liter; mcg/mL; one cubic meter.(NCI) ng/uL; ug/mL

C73738 mg/animal Milligram per A unit of measure expressed in milligram(s) per mg/animal Animal animal.

C67015 mg/dL Milligram per A unit of mass concentration defined as the Milligram per Deciliter Deciliter; mg% concentration of one milligram of a substance in unit volume of the mixture equal to one cubic deciliter or 100 cubic centimeters. It is also a unit of mass density (volumic mass) defined as the density of substance which mass equal to one milligram occupies the volume one cubic deciliter or 100 cubic centimeters.(NCI)

C67399 mg/day Milligram per A unit of measure referring to the ratio between mass Milligram per 24 Hours Day expressed in milligrams per day.(NCI)

C74993 mg/g/day Milligram per A dose calculation unit expressed in milligram(s) per mg/g/day Gram per Day gram per period of time equal to twenty-four hours. (NCI)

C73740 mg/g/h Milligram per A dose calculation unit expressed in milligram(s) per mg/g/h Gram per Hour gram per period of time equal to sixty minutes. (NCI)

C73741 mg/g/min Milligram per A dose calculation unit expressed in milligram(s) per mg/g/min Gram per Minute gram per period of time equal to sixty seconds. (NCI)

C66969 mg/h Milligram per A unit of mass flow rate equivalent to the rate at which Milligram per Hour Hour one thousandth of a gram of matter travels to a given object or space over a period of time equal to one hour.(NCI)

C67401 mg/kg Milligram per A unit of a mass fraction expressed as a number of Milligram per Kilogram Kilogram milligrams of substance per kilogram of mixture. The unit is also used as a dose calculation unit.(NCI)

C66976 mg/kg/day Milligram per A dose calculation unit expressed in milligram(s) per mg/kg/day Kilogram per kilogram per period of time equal to twenty-four Day hours. (NCI)

C71362 mg/kg/h Milligram per A dose calculation unit equal to one thousandth of a Milligram per Kilogram per Hour Kilogram per gram of a preparation per one kilogram of body mass Hour administered per unit of time equal to one hour.(NCI)

C71207 mg/kg/min Milligram per A dose calculation unit equal to one thousandth of a Milligram per Kilogram per Minute Kilogram per gram of a preparation per one kilogram of body mass Minute administered per unit of time equal to one minute.(NCI)

C67402 mg/m2 Milligram per A unit of area density equal to approximately Milligram per Square Meter Square Meter 2.94935E-5 ounce per square yard. Also used as a dose calculation unit.(NCI)

C66974 mg/m2/day Milligram per A dose calculation unit expressed in milligram(s) per mg/m2/day Square Meter per square meter per period of time equal to twenty-four Day hours. (NCI)

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 418 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C71620 - UNIT - Unit Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C73743 mg/m2/h Milligram per A dose calculation unit expressed in milligram(s) per mg/m2/h Square Meter per square meter per period of time equal to sixty minutes. Hour (NCI)

C73744 mg/m2/min Milligram per A dose calculation unit expressed in milligram(s) per mg/m2/min Square Meter per square meter per period of time equal to sixty seconds. Minute (NCI)

C73742 mg/min Milligram per Milligrams per minute. mg/min Minute

C48154 min Minute Unit of A unit measure of time equal to 60 seconds.(NCI) Minute Time

C70507 mkat Millikatal A unit of catalytic activity measurement equal to one Millikatal thousandth of one katal (10E-3 katal).(NCI)

C28251 mm Millimeter A unit of measure equal to one thousandth of a meter. Millimeter (NCI)

C67419 mm/h Millimeter per A unit of both speed (scalar) and velocity (vector), Millimeter per Hour Hour defined as the distance of one millimeter travels per unit time equal to one hour.(NCI)

C65104 mm2 Square A unit of area measurement equal to a square Square Millimeter Millimeter measuring one millimeter on each side. One square millimeter is equal to 10(E-2) square centimeter and 10(E-6) square meter.(NCI)

C49670 mmHg Millimeter of A unit of pressure equal to 0.001316 atmosphere and Millimeter of Mercury Mercury equal to the pressure indicated by one millimeter rise of mercury in a barometer at the Earth's surface. (NCI)

C73764 mmHg/sec Millimeter of A rate of inflation or deflation of a manometric device mmHg/sec Mercury per based on the unit of pressure equal to 133,332 Pa or Second 1.316E10-3 standard atmosphere during period of time equal to one sixtieth of a minute. (NCI)

C48513 mmol Millimole A unit of amount of substance equal to 0.001 Millimole mole.(NCI)

C64387 mmol/L Millimole per A unit of concentration (molarity unit) equal to one Millimole per Liter Liter; umol/mL; thousandth of a mole (10E-3 mole) of solute per one Micromole per liter of solution.(NCI) Milliliter; mol/m3; Mole per Cubic Meter; mcmol/mL; mmol/L; nmol/uL

C67420 mmol/day Millimole per 24 A unit of amount of substance flow rate equivalent to Millimole per 24 Hours Hours the rate at which one thousandth of a mole of substance travels or is delivered to a given object or space over a period of time equal to 24 hours.(NCI)

C68740 mmol/g Millimole per A unit amount of substance content (molality unit) Mole per Kilogram Gram defined as one mole of solute per one kilogram of solvent.(NCI)

C68892 mmol/kg Millimole per A unit of amount of substance content (molality unit) Millimole per Kilogram Kilogram defined as one thousandth of mole (10E-3 mole) of solute per one kilogram of solvent.(NCI)

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 419 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C71620 - UNIT - Unit Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C42539 mol Mole A unit defined as the amount of substance that contains Mole as many elementary units as there are atoms in 0.012 kg of carbon-12. When the mole is used, the elementary entities must be specified and may be atoms, molecules, ions, electrons, other particles, or specified groups of such particles.(NCI)

C48555 mol/L Mole per Liter; A unit of concentration (molarity unit) equal to one Mole per Liter mol/L; mmol/mL mole of solute in one liter of solution.(NCI)

C68893 mol/g Mole per Gram A unit of amount of substance content (molality unit) Mole per Gram defined as one mole of solute per one gram of solvent.(NCI)

C68891 mol/mL Mole per A unit of concentration (molarity unit) equal to one Mole per Milliliter Milliliter mole of solute in one milliliter of solution.(NCI)

C68894 mol/mg Mole per A unit of amount of substance content (molality unit) Mole per Milligram Milligram defined as one mole of solute per one milligram of solvent.(NCI)

C70455 mol/mol Mole per Mole A unit of fraction expressed as the ratio of the amount Mole per Mole of substance of solute in moles to the amount of substance of the mixture in moles.(NCI)

C41140 msec Millisecond A unit of time, which is equal to one thousandth of a Millisecond second.(NCI)

C67352 nCi Nanocurie A unit of radioactivity equal to one billionth of Curie Nanocurie or 37 Becquerels, and corresponding to a radioactivity of 37 atomic disintegrations per second.(NCI)

C69188 nL Nanoliter A unit of volume equal to one billionth of a liter Nanoliter (10E-9 liter).(NCI)

C48516 ng Nanogram A unit of mass equal to one billionth (10E-9) of a Nanogram gram, or one millionth (10E-6) of a milligram.(NCI)

C67327 ng/L ug/m3; A unit of mass concentration defined as the Nanogram per Liter Microgram per concentration of one nanogram of a substance per one Cubic Meter; liter of the mixture, or one picogram of a substance in ng/L; pg/mL unit volume of the mixture equal to one milliliter, or one microgram of a substance per one cubic meter of the mixture. The concept also refers to the metric unit of mass density (volumic mass) defined as the density of substance which mass equal to one nanogram occupies the volume one liter.(NCI)

C67326 ng/dL Nanogram per A unit of mass concentration defined as the Nanogram per Deciliter Deciliter concentration of one nanogram of a substance in unit volume of the mixture equal to one deciliter. The concept also refers to the unit of mass density (volumic mass) defined as the density of substance which mass equal to one nanogram occupies the volume one deciliter.(NCI)

C70508 nkat Nanokatal A unit of catalytic activity measurement equal to one Nanokatal billionth of one katal (10E-9 katal).(NCI)

C70510 nkat/L Nanokatal per A unit of catalytic activity concentration defined as the Nanokatal per Liter Liter catalytic activity of the component equal to one billionth of one katal (10E-9 katal) in the unit volume of the system equal to one liter.(NCI)

C67328 nm Nanometer A unit of length equal to one billionth of a meter Nanometer (10E-9 meter). Nanometer is used as a unit for light wavelength measurement.(NCI)

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 420 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C71620 - UNIT - Unit Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C48517 nmol Nanomole A unit of amount of substance equal to one billionth Nanomole (10E-9) of a mole.(NCI)

C67432 nmol/L Nanomole per A unit of concentration (molarity unit) equal to one Nanomole per Liter Liter billionth of a mole (10E-9 mole) of solute in one liter of solution.(NCI)

C92613 nmol/mL/min Nanomole per A unit of concentration (molarity unit) equal to one Nanomole per Minute per Milliliter Milliliter per billionth of a mole (10E-9 mole) of solute in one Minute milliliter of solution to be administered per minute of time.

C73767 nsec Nanosecond A unit of time equal to one billionth of a second. (NCI) nsec

C42554 ohm Ohm A unit of electrical resistance equal to the resistance Ohm between two points on a conductor when a potential difference of one volt between them produces a current of one Ampere. Ohm is also used to measure impedance and reactance for complex resistance. A measurement in ohms is the reciprocal of a measurement in Siemens. (NCI)

C67330 osm Osmole A unit of osmotic pressure equal to that of an ideal Osmole solution of a nondissociating substance that has a concentration of one mole of solute per liter of solution.(NCI)

C48519 oz Ounce A unit of mass, the avoirdupois ounce is equal to 1/16 Ounce pound, or 28.3495 grams, or 0.911 457 troy ounce.(NCI)

C45997 pH pH A measure of the acidity or alkalinity of a fluid on a pH scale of 0 to 14.(NCI)

C69189 pL Picoliter A unit of volume equal to one trillionth of a liter pL (10E-12 liter). (NCI)

C66967 per min Per Minute The number of occurrences of something within a Per Minute minute of time.(NCI)

C66965 per sec Per Second The number of occurrences of something within a Per Second second of time.(NCI)

C64551 pg Picogram A unit of mass equal to one trillionth of a gram Picogram (10E-12 gram).(NCI)

C67331 pg/dL Picogram per Picograms per deciliter. pg/dL Deciliter

C70509 pkat Picokatal A unit of catalytic activity measurement equal to Picokatal trillionth of one katal (10E-12 katal).(NCI)

C69148 pm Picometer A unit of length equal to one trillionth of a meter Picometer (10E-12 meter).(NCI)

C65045 pmol Picomole A unit of amount of substance equal to a trillionth Picomole (10E-12) of a mole.(NCI)

C67434 pmol/L Picomole per A unit of concentration (molarity unit) equal to one Picomole per Liter Liter; fmol/mL; trillionth of a mole (10E-12 mole) in one liter of Femtomole per solution.(NCI) Milliliter

C70565 ppb Part per Billion A unit of measure referring to one entity counted per Per Billion one billion entities.(NCI)

C48523 ppm Part per Million A unit of measurement referring to one entity counted Part Per Million per one million entities.(NCI)

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 421 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C71620 - UNIT - Unit Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C69112 ppth Part per A unit of proportion equal to 10E-3.(NCI) Part per Thousand Thousand

C70566 pptr Parts per Trillion A unit of measure referring to one entity counted per Per Trillion one trillion entities.(NCI)

C73768 psec Picosecond A unit of time equal to one trillionth of a second. psec (NCI)

C67334 psi Pounds per A unit of pressure equivalent to 6.894757 kilopascals, Pound per Square Inch Square Inch or 703.0696 kilograms per square meter, or 51.71507 millimeters of mercury.(NCI)

C70469 rpm Revolution per A unit of frequency equal to one revolution per unit of Revolution per Minute Minute time equal to one minute.(NCI)

C68858 scm m3; Standard A unit used in physical chemistry to express the m3 Cubic Meter amount of substance of an ideal gas in one cubic meter at standard conditions: temperature 273.15 K and pressure of one atmosphere (101.325 kilopascals).(NCI)

C42535 sec Second The second is a unit of time with a duration of 919 263 Second 177 0 periods of the specified light radiation corresponding to the transition between the two hyperfine levels of the cesium 133 atom in its ground state at 0 K. According to the convention, 60 seconds constitute one minute; 3,600 seconds constitute one hour. Abbreviation Sec. is acceptable in non-scientific usage only.(NCI)

C48544 tsp Teaspoon Dosing A unit of volume used in pharmacy equal to 5 Teaspoon Dosing Unit Unit milliliters.(NCI)

C65132 tuberculin unit Tuberculin Unit An arbitrary unit of tuberculin dosage defined by Tuberculin Unit comparison of clinical response with a preparation of the purified protein derivative standardized for use in humans for tuberculin skin test reaction.(NCI)

C70506 tuberculin unit/mL Tuberculin Unit A unit of biologic activity of tuberculin expressed as a Tuberculin Unit per Milliliter per Milliliter number of arbitrary units of tuberculin in one milliliter of preparation.(NCI)

C48507 uCi Microcurie; A unit of radioactivity equal to one millionth of a Microcurie mcCi Curie or 37 kilobecquerels, and corresponding to a radioactivity of 37 000 atomic disintegrations per second.(NCI)

C71173 uCi/L Microcurie per A unit of volumetric radioactivity concentration Microcurie per Liter Liter; mcCi/L defined as a concentration of a radionuclide with an activity equal to one millionth of a Curie per unit volume equal to one liter.(NCI)

C70571 uCi/kg Microcurie per A unit of specific radioactivity (massic activity) equal Microcurie per Kilogram Kilogram; to activity of one microcurie of the sample with total mcCi/kg mass of one kilogram.(NCI)

C73726 uEq Microequivalent A unit of relative amount of a substance equal to one uEq millionth of an equivalent weight.(NCI)

C67405 uIU/mL Micro-Internatio Microinternational units per milliliter. uIU/mL nal Unit per milliliter; mIU/L; mcIU/mL; uIU/mL

C48153 uL mcL; Microliter; A unit of volume accepted for use with the SI and equal uL mm3 to one millionth of a liter (10E-6 liter).(NCI)

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 422 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C71620 - UNIT - Unit Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C69175 uL/mL Microliter per A unit of volume fraction expressed as a number of Microliter per Milliliter Milliliter; microliters of the constituent per the volume of the mcL/mL system represented in milliliters.(NCI)

C73736 uOsM Microosmole A unit of osmotic pressure equal to one millionth of an uOsM osmole or the osmotic pressure of a 10E-6 molar solution of a substance that does not dissociate. (NCI)

C71175 uV Microvolt; mcV A unit of an electric potential and electromotive force Microvolt equal to one millionth of a volt.(NCI)

C48152 ug Microgram; mcg The unit of mass equal to one millionth of a gram or Microgram one thousandth of a milligram.(NCI)

C67306 ug/L mg/m3; A unit of mass concentration defined as the Microgram per Liter Microgram per concentration of one microgram of a substance per Liter; Milligram unit volume of the mixture equal to one liter. The per Cubic Meter; concept also refers to the unit of mass density Nanogram per (volumic mass) defined as the density of substance Milliliter; ug/L; which mass equal to one microgram occupies the ng/mL; mcg/L volume one liter.(NCI)

C73728 ug/animal Microgram per A unit of measure expressed in microgram(s) per ug/animal Animal animal.

C67305 ug/dL Microgram per A unit of mass concentration defined as the ug/dL Deciliter concentration of one microgram of a substance per unit volume of the mixture equal to one deciliter. The concept also refers to the unit of mass density (volumic mass) defined as the density of substance which mass equal to one microgram occupies the volume one deciliter. (NCI)

C71205 ug/day Microgram per A unit of mass flow rate equivalent to the rate at which Microgram per Day Day; mcg/day one millionth of a gram of matter travels to a given object or space over a period of time equal to twenty four hours. Microgram per day is also a dose administration rate unit equal to the rate at which one millionth of a gram of a product is administered per unit of time equal to twenty four hours.(NCI)

C74921 ug/g/day Microgram per A dose calculation unit expressed in microgram(s) per ug/g/day Gram per Day gram per period of time equal to twenty-four hours. (NCI)

C74922 ug/g/h Microgram per A dose calculation unit expressed in microgram(s) per ug/g/h Gram per Hour gram per period of time equal to sixty minutes. (NCI)

C74923 ug/g/min Microgram per A dose calculation unit expressed in microgram(s) per ug/g/min Gram per Minute gram per period of time equal to sixty seconds. (NCI)

C67394 ug/h Micrograms per A unit of mass flow rate equivalent to the rate at which Microgram per Hour Hour; mcg/h one millionth of a gram of matter travels to a given object or space over a period of time equal to one hour.(NCI)

C67396 ug/kg mcg/kg; A unit of a mass fraction expressed as a number of Microgram per Kilogram Microgram per micrograms of substance per kilogram of mixture. The Kilogram; ng/g; unit is also used as a dose calculation unit.(NCI) ug/kg

C73729 ug/kg/day Microgram per A dose calculation unit expressed in microgram(s) per ug/kg/day Kilogram per kilogram per period of time equal to twenty-four Day hours. (NCI)

C73730 ug/kg/h Microgram per A dose calculation unit expressed in microgram(s) per ug/kg/h Kilogram per kilogram per period of time equal to sixty minutes. Hour (NCI)

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 423 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C71620 - UNIT - Unit Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C71210 ug/kg/min Microgram per A dose calculation unit equal to one millionth of a Microgram per Kilogram per Minute Kilogram per gram of a preparation per one kilogram of body mass Minute; Gamma administered per unit of time equal to one per Kilogram per minute.(NCI) Minute; gamma/kg/min; mcg/kg/min

C67312 ug/m2 Microgram per A dose calculation unit expressed in microgram(s) per ug/m2 Square Meter square meter.

C73787 ug/m2/day Microgram per A dose calculation unit expressed in microgram(s) per ug/m2/day Square Meter per square meter per period of time equal to twenty-four Day hours. (NCI)

C73727 ug/m2/h Microgram per A dose calculation unit expressed in microgram(s) per ug/m2/h Square Meter per square meter per period of time equal to sixty minutes. Hour (NCI)

C73733 ug/m2/min Microgram per A dose calculation unit expressed in microgram(s) per ug/m2/min Square Meter per square meter per period of time equal to sixty seconds. Minute (NCI)

C75905 ug/mL/h Microgram per A dose calculation unit expressed in microgram(s) per ug/mL/h Milliliter per milliliter of solution per period of time equal to sixty Hour minutes. (NCI)

C71211 ug/min Micrograms per A unit of mass flow rate equivalent to the rate at which Microgram per Minute Minute; mcg/min one millionth of a gram of matter travels to a given object or space over a period of time equal to one minute. Microgram per minute is also a dose administration rate unit equal to the rate at which one millionth of a gram of a product is administered per unit of time equal to one minute.(NCI)

C70562 ukat Microkatal; A unit of catalytic activity measurement equal to one Microkatal mckat millionth of katal (10E-6 katal).(NCI)

C67397 ukat/L Microkatal per Unit of catalytic activity concentration defined as Microkatal per Liter Liter; mckat/L activity equal to one millionth of katal per one liter of the system volume.(NCI)

C48510 um Micron; mcm A unit of length in metric system equal to 10E-6 Micron meter, or micrometer.(NCI)

C73770 um2 MicroSquare A SI unit of area measurement equal to a square whose Square Micrometer Meter sides are one micrometer long. (NCI)

C67565 um3 Cubic A unit of volume equal to 10E-18 liter or one cubic Attoliter Micrometer micrometer.

C48509 umol Micromole; A unit of amount of substance equal to one millionth Micromole mcmol (10E-6) of a mole.(NCI)

C48508 umol/L Micromole per A unit of concentration (molarity unit) equal to one umol/L Liter one-millionth of a mole (10E-6 mole) of solute per one liter of solution. (NCI)

C67406 umol/day Micromoles per A unit of amount of substance flow rate equivalent to Micromole per 24 Hours Day; mcmol/day the rate at which one millionth of a mole of substance travels to a given object or space over a period of time equal to 24 hours.(NCI)

C73735 umol/mg/min Micromole per A unit of concentration (molarity unit) equal to one umol/mg/min Milligram per millionth of a mole (10E-6 mole) per milligram of a Minute substance per period of time equal to sixty seconds. (NCI)

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 424 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C71620 - UNIT - Unit Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C69149 usec Microsecond A unit of time equal to one millionth of a second. usec (NCI)

C48553 yd Yard A unit of length equal to 3 feet, or 36 inches, or Yard 0.9144 meter.(NCI)

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 425 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C66770 - VSRESU - Units for Vital Signs Results Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C25613 % Percentage A fraction or ratio with 100 understood as the Percentage denominator. (NCI)

C49673 BEATS/MIN Beats per Minute The number of heartbeats measured per minute time. Beats per Minute (NCI)

C49674 BREATHS/MIN Breaths per The number of breaths (inhalation and exhalation) Breaths per Minute Minute taken per minute time. (NCI)

C42559 C Degree Celsius A unit of temperature of the temperature scale Degree Celsius designed so that the freezing point of water is 0 degrees and the boiling point is 100 degrees at standard atmospheric pressure. The current official definition of the Celsius sets 0.01 C to be at the triple point of water and a degree to be 1/273.16 of the difference in temperature between the triple point of water and absolute zero. One degree Celsius represents the same temperature difference as one Kelvin. (NCI)

C44277 F Degree The Fahrenheit temperature scale is named after the Degree Fahrenheit Fahrenheit German physicist Gabriel Fahrenheit (1686-1736), who proposed it in 1724. In this scale, the freezing point of water is 32 degrees Fahrenheit and the boiling point is 212 degrees, placing the boiling and melting points of water 180 degrees apart. In this scale a degree Fahrenheit is 5/9ths of a Kelvin (or of a degree Celsius), and minus 40 degrees Fahrenheit is equal to minus 40 degrees Celsius. (NCI)

C48500 IN Inch A traditional unit of length equal to 2.54 centimeters. Inch (NCI)

C48531 LB Pound A traditional unit of mass. By international agreement, Pound one avoirdupois pound is equal to exactly 0.453 592 37 kilogram, 16 ounces, or 1.215 28 troy pounds. (NCI)

C49668 cm Centimeter A basic unit of length in the former CGS version of Centimeter metric system, equal to one hundredth of a meter or approximately 0.393 700 787 inch. (NCI)

C48155 g Gram A metric unit of mass equal to one one thousandth of a Gram kilogram. (NCI)

C28252 kg Kilogram The basic SI unit of mass. It is defined as the mass of Kilogram an international prototype in the form of a platinum-iridium cylinder kept at Sevres in France. It is the only basic unit still defined in terms of a material object, and also the only one with a prefix [kilo] already in place. A kilogram is equal to 1,000 grams and 2.204 622 6 pounds. (NCI)

C49671 kg/m2 Kilogram Per The SI derived unit of spread rate of a substance by Kilogram Per Square Meter Square Meter mass, used also as a measure of area density. (NCI)

C42569 m2 Square Meter The SI unit of area measurement equal to a square Square Meter whose sides are one meter long. Square meter is equal to 10,000 square centimeters; 0.01 ares; 1.196 square yards; 10.76 square feet; 1550 square inches. (NCI)

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 426 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C66770 - VSRESU - Units for Vital Signs Results Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C49670 mmHg Millimeter of A unit of pressure equal to 0.001316 atmosphere and Millimeter of Mercury Mercury equal to the pressure indicated by one millimeter rise of mercury in a barometer at the Earth's surface. (NCI)

C42554 ohm Ohm A unit of electrical resistance equal to the resistance Ohm between two points on a conductor when a potential difference of one volt between them produces a current of one Ampere. Ohm is also used to measure impedance and reactance for complex resistance. A measurement in ohms is the reciprocal of a measurement in Siemens. (NCI)

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 427 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C67153 - VSTEST - Vital Signs Test Name Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C12472 Adipose Tissue Adipose Tissue A specialized form of connective tissue consisting Adipose Tissue primarily of adipocytes (fat cells), surrounded by a meshwork of collagen fibers.

C49680 Body Frame Size Body Frame Size The categorization of a person's body frame into small, Body Frame Size medium and large based on the measurement of wrist circumference or the breadth of the elbow. (NCI)

C16358 Body Mass Index Body Mass Index A general indicator of the body fat an individual is Body Mass Index carrying based upon the ratio of weight to height. (NCI)

C25157 Body Surface Area Body Surface A measure of the 2-dimensional extent of the body Body Surface Area Area surface (i.e., the skin). Body surface area (BSA) can be calculated by mathematical formula or from a chart that relates height to weight. BSA is often an important factor in dosing. (NCI)

C25299 Diastolic Blood Pressure Diastolic Blood The blood pressure after the contraction of the heart Diastolic Blood Pressure Pressure while the chambers of the heart refill with blood. (NCI)

C100946 Forearm Circumference Forearm The distance around an individual's forearm. Forearm Circumference Circumference

C81255 Head Circumference Head A circumferential measurement of the head at the Head Circumference Circumference widest point, which is traditionally above the eyebrows.

C49677 Heart Rate Heart Rate The number of heartbeats per unit of time, usually Heart Rate expressed as beats per minute. (NCI)

C25347 Height Height The vertical measurement or distance from the base to Height the top of an object; the vertical dimension of extension. (NCI)

C100947 Hip Circumference Hip The distance around an individual's pelvic area or hips. Hip Circumference Circumference

C84372 Knee to Heel Length Knee to Heel A measurement of the length of the lower leg from the Knee to Heel Length Measurement Length; Lower top of the knee to the bottom of the heel. This Leg Length measurement may be taken with a knemometer or calipers. (NCI)

C71258 Lean Body Mass Lean Body Mass The weight of all organs and tissue in an individual less Lean Body Mass the weight of the individual's body fat.

C49679 Mean Arterial Pressure Mean Arterial The mean pressure of the blood within the arterial Mean Arterial Pressure Pressure circulation. The arterial pressure may be directly measured by insertion of an intra-arterial catheter connected to a transducer. The mean arterial pressure (MAP) can be calculated by subsequent analysis of the waveform. MAP can be approximated without an invasive procedure using the following formula: diastolic pressure plus 1/3 of the pulse pressure, where pulse pressure is systolic pressure - diastolic pressure. (NCI)

C100945 Pulse Pressure Pulse Pressure The change in systolic to diastolic pressure which Pulse Pressure produces a pulse.

C49676 Pulse Rate Pulse Rate The rate of the pulse as observed in an artery, Pulse Rate expressed as beats per minute. It can be measured at several anatomical sites, including the wrist, neck, temple, groin, behind the knees, or on top of the foot. (NCI)

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 428 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C67153 - VSTEST - Vital Signs Test Name Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C49678 Respiratory Rate Respiratory Rate The rate of breathing (inhalation and exhalation) Respiratory Rate measured within in a unit time, usually expressed as breaths per minute. (NCI)

C87054 Sagittal Abdominal Diameter Sagittal A standard measure of visceral obesity, or abdominal Sagittal Abdominal Diameter Abdominal fat, which is measured from the patient's back to upper Diameter abdomen between the bottom of the rib cage and the top of the pelvic area. This measurement may be taken with the patient standing or in the supine position. (NCI)

C98785 Subscapular Skinfold Subscapular A measurement of the thickness of a pinch of skin Subscapular Skinfold Thickness Thickness Skinfold situated below or on the underside of the scapula. Thickness (NCI)

C25298 Systolic Blood Pressure Systolic Blood The blood pressure during the contraction of the left Systolic Blood Pressure Pressure ventricle of the heart.

C25206 Temperature Temperature The property of a body or region of space that Temperature determines whether or not there will be a net flow of heat into it or out of it from a neighboring body or region and in which direction (if any) the heat will flow, perceptible by living organism as a somatic sensation of cold or heat. It is a measure of the average translational kinetic energy associated with the disordered microscopic motion of atoms and molecules. Temperature is measured in one of the three standard temperature scales: Celsius, Kelvin, and Fahrenheit. (NCI)

C98793 Triceps Skinfold Thickness Triceps Skinfold A measurement of the thickness of a pinch of skin on Triceps Skinfold Thickness Thickness the triceps. (NCI)

C100948 Waist Circumference Waist The distance around an individual's midsection or Waist Circumference Circumference waist.

C25208 Weight Weight The vertical force exerted by a mass as a result of Weight gravity. (NCI)

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 429 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C66741 - VSTESTCD - Vital Signs Test Code Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C16358 BMI Body Mass Index A general indicator of the body fat an individual is Body Mass Index carrying based upon the ratio of weight to height. (NCI)

C12472 BODYFAT Adipose Tissue A specialized form of connective tissue consisting Adipose Tissue primarily of adipocytes (fat cells), surrounded by a meshwork of collagen fibers.

C25157 BSA Body Surface A measure of the 2-dimensional extent of the body Body Surface Area Area surface (i.e., the skin). Body surface area (BSA) can be calculated by mathematical formula or from a chart that relates height to weight. BSA is often an important factor in dosing. (NCI)

C25299 DIABP Diastolic Blood The blood pressure after the contraction of the heart Diastolic Blood Pressure Pressure while the chambers of the heart refill with blood. (NCI)

C100946 FARMCIR Forearm The distance around an individual's forearm. Forearm Circumference Circumference

C49680 FRMSIZE Body Frame Size The categorization of a person's body frame into small, Body Frame Size medium and large based on the measurement of wrist circumference or the breadth of the elbow. (NCI)

C81255 HDCIRC Head A circumferential measurement of the head at the Head Circumference Circumference widest point, which is traditionally above the eyebrows.

C25347 HEIGHT Height The vertical measurement or distance from the base to Height the top of an object; the vertical dimension of extension. (NCI)

C100947 HIPCIR Hip The distance around an individual's pelvic area or hips. Hip Circumference Circumference

C49677 HR Heart Rate The number of heartbeats per unit of time, usually Heart Rate expressed as beats per minute. (NCI)

C84372 KNEEHEEL Knee to Heel A measurement of the length of the lower leg from the Knee to Heel Length Measurement Length; Lower top of the knee to the bottom of the heel. This Leg Length measurement may be taken with a knemometer or calipers. (NCI)

C71258 LBM Lean Body Mass The weight of all organs and tissue in an individual less Lean Body Mass the weight of the individual's body fat.

C49679 MAP Mean Arterial The mean pressure of the blood within the arterial Mean Arterial Pressure Pressure circulation. The arterial pressure may be directly measured by insertion of an intra-arterial catheter connected to a transducer. The mean arterial pressure (MAP) can be calculated by subsequent analysis of the waveform. MAP can be approximated without an invasive procedure using the following formula: diastolic pressure plus 1/3 of the pulse pressure, where pulse pressure is systolic pressure - diastolic pressure. (NCI)

C49676 PULSE Pulse Rate The rate of the pulse as observed in an artery, Pulse Rate expressed as beats per minute. It can be measured at several anatomical sites, including the wrist, neck, temple, groin, behind the knees, or on top of the foot. (NCI)

C100945 PULSEPR Pulse Pressure The change in systolic to diastolic pressure which Pulse Pressure produces a pulse.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 430 of 431 - CDISC Controlled Terminology SDTM - 2012-03-23 C66741 - VSTESTCD - Vital Signs Test Code Codelist extensible: Yes

CDISC NCI Code CDISC Submission Value Synonym CDISC Definition NCI Preferred Term

C49678 RESP Respiratory Rate The rate of breathing (inhalation and exhalation) Respiratory Rate measured within in a unit time, usually expressed as breaths per minute. (NCI)

C87054 SAD Sagittal A standard measure of visceral obesity, or abdominal Sagittal Abdominal Diameter Abdominal fat, which is measured from the patient's back to upper Diameter abdomen between the bottom of the rib cage and the top of the pelvic area. This measurement may be taken with the patient standing or in the supine position. (NCI)

C98785 SSSKNF Subscapular A measurement of the thickness of a pinch of skin Subscapular Skinfold Thickness Skinfold situated below or on the underside of the scapula. Thickness (NCI)

C25298 SYSBP Systolic Blood The blood pressure during the contraction of the left Systolic Blood Pressure Pressure ventricle of the heart.

C25206 TEMP Temperature The property of a body or region of space that Temperature determines whether or not there will be a net flow of heat into it or out of it from a neighboring body or region and in which direction (if any) the heat will flow, perceptible by living organism as a somatic sensation of cold or heat. It is a measure of the average translational kinetic energy associated with the disordered microscopic motion of atoms and molecules. Temperature is measured in one of the three standard temperature scales: Celsius, Kelvin, and Fahrenheit. (NCI)

C98793 TRSKNF Triceps Skinfold A measurement of the thickness of a pinch of skin on Triceps Skinfold Thickness Thickness the triceps. (NCI)

C25208 WEIGHT Weight The vertical force exerted by a mass as a result of Weight gravity. (NCI)

C100948 WSTCIR Waist The distance around an individual's midsection or Waist Circumference Circumference waist.

Source: NCI EVS Terminology Resources website: http://www.cancer.gov/cancertopics/terminologyresources/page6 Source Date: 2012-03-23 - page 431 of 431 -