RBHS Laboratory Safety Plan
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UMDNJ LABORATORY SAFETY PLAN TABLE OF CONTENTS (This Laboratory Safety Plan will be updated frequently. Please see http://www2.umdnj.edu/eohssweb/publications/lsp.htm for updated sections) 1. INTRODUCTION AND INSTRUCTIONS .............................1-1 1.A Introduction ..............................................1-1 1.A.1 Purpose ...........................................1-1 1.A.2 Background ........................................1-1 1.A.3 Scope/Applicability ...................................1-1 1.A.4 Designation of Responsibility ...........................1-2 1.B Instructions on How to Use this Plan...........................1-2 1.C Laboratory Safety Plan Survey ...............................1-5 2. STANDARD OPERATING PROCEDURES ..........................2-1 2.A Training Programs and Requirements ..........................2-1 2.A.1 Training Overview....................................2-1 2.A.3 Radiation Safety Training..............................2-1 2.A.4 Training Requirements for Visitors to the Laboratory .........2-2 2.A.5 Laboratory Specific Training ............................2-2 2.A.6 Documentation of Training.............................2-2 2.B Laboratory Security ........................................2-3 2.C Laboratory Door Signage ...................................2-3 2.D Working Alone............................................2-3 2.E Unattended Operation of Equipment ...........................2-4 2.F Fire Safety...............................................2-4 2.F.1 Maintenance of Egress Corridors ........................2-4 2.F.2 Maintenance of Areas Around Emergency Equipment ........2-5 2.F.3 Bunsen Burners .....................................2-5 2.G Policy on Visitors..........................................2-5 2.G.1 General ............................................2-5 2.G.2 Visitors under the age of 18 ............................2-5 2.G.3 Laboratory Workers Who Are Under the Age of 18 ..........2-6 2.H Laboratory Safety Audits ....................................2-6 2.I Laboratory Vacating Procedures ..............................2-7 2.J Material Safety Data Sheets .................................2-7 2.K Chemical Inventories.......................................2-7 2.L Refrigerators, Warm and Cold Rooms .........................2-8 2.M Disposal of Broken or Outdated Equipment .....................2-9 2.M.1 Refrigerator/Freezer ..................................2-9 2.M.2 Laboratory Equipment that contains a Radioactive Source ....2-9 2.M.3 Computers and other Lead-Containing Equipment ...........2-9 2.M.4 Other Equipment ...................................2-10 All UMDNJ Campuses 2.N Ban on Mercury-Containing Thermometers and Other Devices .....2-10 2.O Centrifuge Safety ........................................2-11 2.O.1 Responsibility for Centrifuges ..........................2-11 2.O.2 Training and Supervision of Operators ..................2-11 2.O.3 Operating Manuals ..................................2-12 2.O.4 Know When to Derate and When to Retire Your Rotors ......2-12 2.O.5 Have Rotors Inspected Periodically .....................2-12 2.O.6 Maintain a Logbook .................................2-13 2.O.7 Clean Your Rotor Without Damaging It ..................2-13 2.O.8 Do Not Use An Unapproved Rotor ......................2-13 2.O.9 Use The Following Safety Practices for Nitrocellulose Tubes ..2-13 2.O.10 User Error: The Biggest Cause of Rotor Incidents ..........2-14 2.O.11 Safe Work Practices ................................2-14 2.O.12 Online Resources for Centrifuge Safety .................2-14 3. STORAGE AND HANDLING OF CHEMICALS .......................3-1 3.A Introduction ..............................................3-1 3.B Identification of Chemical Substances ..........................3-1 3.C Storage of Hazardous Chemical Substances ....................3-1 3.D Steps to Organize Hazardous Substances According to Hazard Class...........................................3-2 3.E Segregation of Chemicals ...................................3-3 3.F Storage of Flammable and Combustible Chemicals ...............3-3 3.G Storage of Corrosives ......................................3-7 3.H Toxic or Poisonous Materials ................................3-8 3.I Oxidizers................................................3-8 3.J Compressed Gases, Cryogenic Liquids and Dry Ice ...............3-8 3.J.1 Compressed Gases ..................................3-8 3.J.2 Cryogenic Liquids ....................................3-9 3.J.3 Special Precautions for the Use of Dry Ice ................3-10 3.K Low-hazard Materials .....................................3-10 3.K Narcotics...............................................3-10 3.M Peroxide-forming and Shock Sensitive Compounds ..............3-10 3.M.1 Examples of Peroxide-Forming and Shock Sensitive Compounds ..........................3-10 3.M.2 Precautions for Peroxide-Forming & Shock Sensitive ......3-11 3.N Sodium Azide ...........................................3-12 3.O Perchloric Acid ..........................................3-12 3.P Pyrophoric and Reactive Chemicals ..........................3-13 3.Q Radioactive Materials .....................................3-13 3.R Biohazardous Materials ...................................3-13 3.S Select Agents ...........................................3-14 3.T Packing and Moving Chemicals .............................3-14 April 2010 -ii- Table of Contents 4. ADDITIONAL PRECAUTIONS FOR PARTICULARLY HAZARDOUS SUBSTANCES ....................................4-1 4.A Introduction ..............................................4-1 4.B Standard Operating Procedures (SOP) .........................4-2 4.C Designated Areas for Use of Particularly Hazardous Substances .....4-5 4.D Training.................................................4-5 4.E Containment Equipment ....................................4-5 4.F Reproductive Hazard Evaluation Program ......................4-6 4.G Substances with Unknown Toxicity............................4-7 4.H Weighing Techniques for Hazardous Substances ................4-7 4.I Pyrophoric and Reactive Substances ..........................4-9 5. PRIOR APPROVAL.............................................5-1 5.A System for Situations Requiring Prior Approval ..................5-1 5.A.1 Visitors who are under the age of 18 in the laboratory .......5-1 5.A.2 Initial purchase and use of substances which are acutely toxic, carcinogenic, reproductive toxins or pyrophoric/reactive ......5-1 5.A.3 Live-animal use of hazardous substances .................5-1 5.A.4 Use of chemicals in a ductless chemical hood ..............5-1 5.A.5 Use of Respiratory Protection ...........................5-1 5.A.6 Operations that will result in the generation of mixed radioactive/ hazardous chemical waste .............................5-1 5.A.7 Purchase of radionuclide-labeled hazardous chemical ........5-1 5.A.8 Research classified as "non-exempt" as per NIH Guidelines on Recombinant DNA ...................................5-2 5.A.9 Use of a etiologic agent which requires a higher Biosafety Level that agents currently in use. ............................5-2 5.A.10 Non-laboratory storage areas for flammable materials .......5-2 5.A.11 Moving into a vacated laboratory .......................5-2 5.A.12 Disposal of hazardous chemical waste by any means other than the procedure discussed in the UMDNJ Hazardous Waste Management Plan ...................................5-2 5.A.13 Outside contractors working in a laboratory ...............5-2 5.A.14 Storage of more than 10 gallons of flammable liquids in a laboratory .........................................5-3 5.A.15 Permission for undergraduate students to work during off-hours ....................................5-3 5.A.16 Renovations to an existing laboratory ....................5-3 5.A.17 Use of CDC-listed Select Agents .......................5-3 5.A.18 High School Students Working in Laboratory ..............5-3 -iii- April 2010 All UMDNJ Campuses 6. EMERGENCY PROCEDURES AND EQUIPMENT .....................6-1 6.A Posting of the Emergency Flipchart............................6-1 6.B Emergency Equipment .....................................6-1 6.C In the Event of a Fire.......................................6-1 6.C.1 Notes and Precautions ................................6-1 6.C.2 If You Discover Fire or Smoke ..........................6-2 6.C.3 If You Hear or See a Fire Alarm: ........................6-2 6.C.4 Clothing Fires .......................................6-2 6.C.5 Use of Fire Blankets ..................................6-3 6.D Chemical Spill............................................6-3 6.D.1 Notes and Precautions ................................6-3 6.D.2 Minor Chemical Spills .................................6-3 6.D.3 Small or Large Chemical Spill ...........................6-4 6.E Safety Showers...........................................6-4 6.E.1 Directions for Use of a Safety Shower ....................6-4 6.E.2 Inspections of Safety Showers ..........................6-4 6.F Eyewash Fountains and Hoses ...............................6-5 6.F.1 Directions for Use of an Eyewash ........................6-5 6.F.2 Inspection of Eyewash Fountains and Hoses ...............6-5 6.G Medical Emergencies ......................................6-5 6.G.1 Planning for Medical Emergencies .......................6-5 6.G.2 Reporting of Incidents .................................6-5 6.H Flooding Situations ........................................6-6 6.H.1 Electrical Hazards ....................................6-6