OriGene Technologies, Inc. 9620 Medical Center Drive, Ste 200 Rockville, MD 20850, US Phone: +1-888-267-4436 [email protected] EU: [email protected] CN: [email protected] Product datasheet for TL310148V

PRPSAP2 Human shRNA Lentiviral Particle ( ID 5636) Product data:

Product Type: shRNA Lentiviral Particles Product Name: PRPSAP2 Human shRNA Lentiviral Particle (Locus ID 5636) Locus ID: 5636 Synonyms: PAP41 Vector: pGFP-C-shLenti (TR30023) Format: Lentiviral particles RefSeq: NM_001243936, NM_001243940, NM_001243941, NM_001243942, NM_002767, NM_001353096, NM_001353097, NM_001353098, NM_001353099, NM_001353100, NM_001353101, NM_001353102, NM_001353103, NM_001353104, NM_001353105, NM_001353106, NM_001353107, NM_002767.1, NM_002767.2, NM_002767.3, NM_001243941.1, NM_001243942.1, NM_001243936.1, NM_001243940.1, BC106050, BC101670, BC101672, BC143475, NM_001243936.2, NM_002767.4 Summary: This encodes a protein that associates with the enzyme phosphoribosylpyrophosphate synthetase (PRS). PRS catalyzes the formation of phosphoribosylpyrophosphate which is a substrate for synthesis of purine and pyrimidine nucleotides, , and NAD. PRS exists as a complex with two catalytic subunits and two associated subunits. This gene encodes a non-catalytic associated subunit of PRS. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2011] shRNA Design: These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact [email protected]. If you need a special design or shRNA sequence, please utilize our custom shRNA service.

This product is to be used for laboratory only. Not for diagnostic or therapeutic use. View online » ©2021 OriGene Technologies, Inc., 9620 Medical Center Drive, Ste 200, Rockville, MD 20850, US 1 / 2 PRPSAP2 Human shRNA Lentiviral Particle (Locus ID 5636) – TL310148V

Performance OriGene guarantees that the sequences in the shRNA expression cassettes are verified to Guaranteed: correspond to the target gene with 100% identity. One of the four constructs at minimum are guaranteed to produce 70% or more gene expression knock-down provided a minimum transfection efficiency of 80% is achieved. Western Blot data is recommended over qPCR to evaluate the silencing effect of the shRNA constructs 72 hrs post transfection. To properly assess knockdown, the gene expression level from the included scramble control vector must be used in comparison with the target-specific shRNA transfected samples.

For non-conforming shRNA, requests for replacement product must be made within ninety (90) days from the date of delivery of the shRNA kit. To arrange for a free replacement with newly designed constructs, please contact Technical Services at [email protected]. Please provide your data indicating the transfection efficiency and measurement of gene expression knockdown compared to the scrambled shRNA control (Western Blot data preferred).

This product is to be used for laboratory only. Not for diagnostic or therapeutic use. ©2021 OriGene Technologies, Inc., 9620 Medical Center Drive, Ste 200, Rockville, MD 20850, US 2 / 2