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FUSF Symposium Program and Abstract Book 2014 (PDF) CurrentCurrent andand FutureFuture ApplicationsApplications of Focused UltrasoundUltrasound 20142014 4th4th InternationalInternational SymposiumSymposium ProgramProgram && AbstractAbstract Book OctoberOctober 12-16,12–16, 20142014 BethesdaBethesda North Marriott Hotel & ConferenceConference Center FFocusedocused Ultrasound Ultrasound Foundation Foundation www.fusfoundation.orgwww.fusfoundation.org | |Charlottesville, Charlottesville, VA VA | |TT 434.220.4993 434.220.4993 Washington,Washington, DC MetroMetro Area, USA FUSF Symposium Ad - Final.pdf 1 9/12/2014 10:36:49 AM Sponsor Acknowledgements Your partner in advancing the field Platinum Sponsors The Focused Ultrasound Foundation was created to improve the lives of millions of patients by accelerating the development and adoption of focused ultrasound. We leverage our independent status to drive progress by: Funding Research A key priority for the Foundation is funding translational studies, applying the growing body of knowledge to complex problems. We organize and conduct research internally and through an C External Awards Program, which funds investigator-initiated M clinical and technical research projects through a competitive peer-reviewed process. Y CM MY CY Bronze Sponsors CMY Fostering K Collaboration We act as a global connector, hosting a variety of workshops and biennial symposia to stimulate innovation and increase awareness. International Society for Thearapeutic Ultrasound Overcoming Barriers Media Partner We partner with industry to help usher this technology through the regulatory and reimbursement processes and move the technology closer to patients. www.fusfoundation.org FUSF_Symposium_2014_Program_Cover_Inside.indd 1 9/29/2014 4:37:28 PM Welcome Messages From the Honorary President It is an exciting time for the fi eld to come together. Great strides have been made in the two years since the last Symposium. From my perspective into Europe and Asia, there has been clear progress in treating neurological disorders, pain management and cancers. Patients with prostate cancer, breast cancer, soft tissue tumors and liver cancer are increasingly offered this non-invasive option, and there is a promising study being discussed this week on treating pancreatic cancer. After more than 25 years in this fi eld, I have personally seen focused ultrasound evolve from a concept to a global treatment reality. Having been involved in technical development and treating tumor patients in China and the UK, I know it requires countless stakeholders working in tandem to make real progress. To continue on this trajectory, I believe we must broaden our scope past our own organizations and fi elds of study to seek out new partnerships and applications for this promising technology. The symposium is an opportunity for both clinicians and scientists in the fi eld to learn from each other and understand how their work reinforces one another. My hope is that with our great efforts, we will work towards establishing international standards or guidelines for devices and clinical applications in the future. With this groundwork laid, I believe we will see the fi eld grow immensely. I look forward to spending time with you over the next several days. Sincerely, Feng Wu, MD, PhD Focused Ultrasound Consultant and Senior Clinical Scientist Oxford University Honorary Symposium President Focused Ultrasound 2014 4th International Symposium 1 Welcome Messages (continued) From the Foundation Chairman Dear Colleagues: Welcome to the 4th International Symposium on Focused Ultrasound. This week, we will take part in the most extensive program we have hosted to date, featuring more than 200 oral and poster presentations. This year’s program allows for nearly four full days of scientifi c talks and engaging discussions, necessitated by signifi cant advances achieved by you — the focused ultrasound community. The fi eld’s momentum is tangible. Since we met last, focused ultrasound is emerging as a relevant option for countless patients as the technology is transitioning from research to clinical uses. The treatment of pain from bone metastases was approved by the U.S. Food and Drug Administration in late 2012, while the number of indications in various stages of research, development and commercialization has skyrocketed, including neurological conditions like essential tremor and Parkinson’s disease; cancers of the breast, pancreas, liver, lung and kidney; as well as agonizing musculoskeletal conditions like osteoid osteoma and back pain. Two prostate devices are currently under FDA review, and enrollment is nearly complete on an essential tremor pivotal study, putting the technology on the path for FDA approval for the fi rst of what we hope will be several neurological applications. The symposium is an important vehicle for disseminating knowledge and sharing ideas, serving as an incubator to foster collaboration and hasten the speed of progress. Please take advantage of the opportunities to establish new partnerships this week. Several special events are planned during the symposium, including keynote talks by Frederic Moll, MD, serial medical device entrepreneur and founder of Intuitive Surgical, the makers of the Da Vinci Surgical System; Andrew von Eschenbach, MD, former Commissioner of the FDA and Director of the NCI; and Rick Hamilton, IBM’s most prolifi c inventor and innovation evangelist. The Focused Ultrasound Foundation is proud to serve as the nexus for the global focused ultrasound ecosystem. We are deeply appreciative of your participation in the symposium and of your steadfast commitment to advancing focused ultrasound. I am confi dent that this event will inspire and facilitate your continued contributions to the growing body of focused ultrasound research and knowledge. In closing, I would like to acknowledge the generosity of our donors and the support of our sponsors. They have made this meeting possible. Thank you. Sincerely, Neal F. Kassell, MD Chairman, Focused Ultrasound Foundation 2 Focused Ultrasound 2014 4th International Symposium Symposium Organizer About the Focused Ultrasound Foundation The Focused Ultrasound Foundation is a medical technology research, education and advocacy organization dedicated to improving the lives of millions of people with serious medical disorders by accelerating the development and adoption of focused ultrasound. Positioned at the nexus of a large, diverse group of stakeholders comprising the focused ultrasound community, the Foundation functions as an independent, unbiased third-party, aligning organizations into a cohesive ecosystem with a single goal: To make this technology available to patients in the shortest time possible. It strives to catalyze progress while instilling a patient-centric sense of urgency. The Foundation works to clear the path to global adoption by organizing and funding research, fostering collaboration, building awareness at our various workshops and symposia, and cultivating the next generation through internships and fellowships. The Foundation is on the leading edge of the venture philanthropy and social entrepreneurship movements and is a model of how private philanthropy can work in concert with academia, industry and government to bridge the gap between research and commercialization. To learn more about focused ultrasound and the Focused Ultrasound Foundation, visit the Foundation’s website: www.fusfoundation.org Organizing Committee Neal F. Kassell, MD, Chair Chairman, Focused Ultrasound Foundation; Professor of Neurosurgery, University of Virginia Jessica Foley, PhD, Co-Vice Chair Scientifi c Director Focused Ultrasound Foundation Arik Hananel, MD, MBA, Co-Vice Chair Medical Director Focused Ultrasound Foundation Robin Jones, Project Lead Director of Clinical Trials Coordination Focused Ultrasound Foundation Focused Ultrasound 2014 4th International Symposium 3 Symposium Organizer (continued) Board of Directors Dorothy N. Batten Edward D. Miller, MD Director, Amazon Conservation Association Former CEO, Johns Hopkins Medicine Former Director, Landmark Communications Frederic H. Moll, MD Lodewijk J.R. de Vink Co-founder, Intuitive Surgical Founding Partner, Blackstone Healthcare Partners, LLC Chairman & CEO, Auris Surgical Robotics, Inc. Former Chairman & CEO, Warner-Lambert Steve H. Rusckowski Eugene V. Fife President and CEO, Quest Diagnostics Inc. Founding Principal, Vawter Capital, LLC Former CEO, Philips Healthcare Former Chairman, Goldman Sachs International Andrew C. von Eschenbach, MD John R. Grisham President, Samaritan Health Initiative Author Former Commissioner, U.S. Food and Drug Administration Former Director, National Cancer Institute Daniel P. Jordan, PhD President Emeritus, Thomas Jefferson Foundation, Inc. Carl P. Zeithaml, PhD Dean and F.S. Cornell Professor of Free Enterprise, Neal F. Kassell, MD McIntire School of Commerce, University of Virginia Chairman, Focused Ultrasound Foundation Professor of Neurosurgery, University of Virginia Scientifi c Program Committee Jean-François Aubry, PhD Hidemi Furusawa, MD Stephen Monteith, MD Institut Langevin Breastopia Namba Hospital Swedish Medical Center Paris, France Miyazaki, Japan Seattle, Washington, United States Jin Woo Chang, MD, PhD Arik Hananel, MD, MBA Alessandro Napoli, MD YUMC Severance Hospital Focused Ultrasound Foundation University of Rome – La Sapienza Seoul, Republic of Korea Charlottesville, Virginia, United States Rome, Italy Christian Chaussy, MD Mark Hurwitz, MD Franco Orsi, MD University of Munich Thomas Jefferson University European
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