Cambridge University Press 978-1-108-81783-7 — Reproductive Medicine for the MRCOG Edited by Siladitya Bhattacharya , Mark Hamilton Index More Information
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Cambridge University Press 978-1-108-81783-7 — Reproductive Medicine for the MRCOG Edited by Siladitya Bhattacharya , Mark Hamilton Index More Information Index access, to fertility treatment, 137–40 arcuate uterus, 41 body mass index (BMI), 9, 10 adenomyosis, 33, 40 aromatase inhibitors, 16, 29 bromocriptine, 19 adhesions ART. See assisted reproduction buffers, culture media, 95–6 intrauterine, 33–4, 35, 40, 41 technology tubal, 31 AS. See Asherman’s syndrome cabergoline, 19 adjuvants/add-ons in assisted ASFR. See Age-Specific Fertility Rate calcium ionophores, 89, 103 reproduction, 91 Asherman’s syndrome (AS), 33–4, 35, cancer treatment, 113. See also fertility artificial egg activation with calcium 40, 41 preservation ionophore, 89, 103 ASRM. See American Society for gonadotoxicity risks of, 113, 114 assisted hatching, 86 Reproductive Medicine mechanisms of fertility damage by, background on, 82–3 assessment. See also infertility 114–15 commonly used, 83–4 assessment ovarian reserve damage by, 114–15 costs of, 83 of donors, surrogates and intended pregnancy outcomes after, 120 embryo glue, 88 parents, 129–30 testicular damage caused by, 46, 115 endometrial receptivity array, 87 embryo, 105–6, 107 CAT. See chlamydia antibody testing endometrial scratching, 84–5, 86 of fertilisation, 101–2, 103 catheters, for embryo transfer, 73 GM-CSF-containing culture media, for fertility preservation, 116–17 CBRS. See cross border reproductive 88 assisted hatching, 86 services IMSI, 89, 101–2 assisted reproduction technology CC. See clomiphene citrate PICSI, 89–90, 101–2 (ART), 68. See also adjuvants/add- Centre for Evidence Based Medicine preimplantation genetic screening, ons in assisted reproduction; (CEBM), 150–1 87, 109–10 laboratory procedures in assisted CF. See cystic fibrosis professional and regulatory body reproduction; specific techniques chemical motility enhancers, 98–9 stances on, 83 access to treatment with, 137–40 chemotherapy. See cancer treatment reproductive immunology decision to stop treatment with, children procedures, 90–1 80–1 disclosure of third-party sperm DNA tests, 90 HFEA role in, 80 conception to, 128–9 time-lapse imaging, 85–6, 106 male factor infertility treatment genetic identity of, 144–5 adoption, 138–9 options in, 52–3 interests and welfare of, 80, 129–30, Age-Specific Fertility Rate (ASFR), techniques used in, 68 137–8, 143, 145, 146 1, 3 unsuccessful, 80–1 posthumous, 120–1, 141–3 air, laboratory, 96 audits, 164 risks to IVF/ICSI conceived, 79 alcohol intake, 8–9, 10, 25–6, 46 autonomy, patient, 136, 137, 140–1, chlamydia antibody testing (CAT), 35 American Society for Reproductive 146 Chlamydia trachomatis, 8, 31, 46 Medicine (ASRM), 24 azoospermia class II cabinets, 94, 95 AMH. See anti-mullerian hormone assisted reproduction treatment cleavage stage embryo transfer, 74 andrology. See male factor infertility options for, 52–3 clinical decision making, 147 anejaculation, 46–7 causes of, 45–7 clinical governance, 163 aneuploidy, PGT for, 87, 109–10 medical treatment options for, 51–2 audits, 164 anorgasmia, 47 surgical treatment options for, 52 external review, 165 anovulatory infertility. See ovulation quality inspections, 164 disorders baby design, 146 quality sampling, 164 antibody testing bacterial vaginosis, 8 quality tours, 164–5 chlamydia, 35 bias, 151–2, 153 risk management/risk assessment, sperm, 51 bicornuate uterus, 41 164 thyroid autoantibodies, 8, 9 biomarkers, for endometriosis, 27 clinical practice guidelines, 153–4 anti-mullerian hormone (AMH), 8 biopsy clomiphene citrate (CC), 14–15, 51–2, antioestrogens, 14–15, 118 embryo, 110–11 56 antiprogestogens, 29 testicular, 51 cocaine use, 9 antral follicle count, 8 blastocyst transfer, 74 Cochrane risk of bias tool, 151–2 167 © in this web service Cambridge University Press www.cambridge.org Cambridge University Press 978-1-108-81783-7 — Reproductive Medicine for the MRCOG Edited by Siladitya Bhattacharya , Mark Hamilton Index More Information Index COCP. See combined oral disclosure of, 128–9 female, 13 contraceptive pill ethical dilemmas involving, 144–6 male, 45–6, 51–2 cohort total fertility rate (CTFR), 1 future relationship with, 127–8 thyroid, 8, 9 combined oral contraceptive pill implication discussion and endocrine tests, for males, 49, 51 (COCP), 20, 28, 29, 71 counselling for, 130, 131 endometrial polyps, 33, 36, 37, 40 co-morbidities, double jeopardy risks selection of, 127–8 endometrial receptivity array (ERA), for patients with, 140–1 dopamine agonists, 19 87 conception, prediction models for, double jeopardy risks, for patients with endometrial scratching, 84, 85, 86 54–6, 57, 63 co-morbidities, 140–1 endometrioma, 24, 26, 29, 36 confidentiality, 141 dye hydrotubation, 10 endometriosis, 22, 24 congenital anomalies, in children dysmenorrhoea, 24–5, 27 aetiopathogenesis of, 22–4 conceived by IVF/ICSI, 79 dyspareunia, 27 description, distribution and consequentialism, 138 classification of, 24, 25, 26 controlled ovarian stimulation. See EBM. See evidence-based medicine diagnosis of, 26–7, 28 ovarian stimulation ectopic pregnancy, 78 direct transplantation theory of, 23 corticosteroids, 90–1 ED. See erectile dysfunction economic burden of, 27–8 counselling EFI. See endometriosis fertility index epidemiology and risk factors of, before cross border reproductive egg. See oocyte 24–6 treatment, 132, 133 egg activation, artificial, 89, 103 genetic factors in, 23, 26 for donors, surrogates and partners, ejaculation, 43, 46–7, 49 immunological processes in, 23–4 130, 131 ejaculatory ducts, transurethral management of infertility associated for fertility preservation, 121 resection of, 52 with, 28–9 HFEA requirement for, 123, 124–5 elective egg freezing, 143–4 management of pain associated with, implication discussion in, 126, 130, elective single-embryo transfer (eSET), 29 131 108 organisation of care for, 29–30 offer of, 125 embryo, moral status of, 140 ovarian endometrioma, 24, 26, 29, in preparation for treatment, 124 embryo biopsy, 110–11 36 types of, 124–5 embryo cryopreservation prevalence of, 22 critical appraisal, literature, 150–4 ethical dilemmas in, 141–4 socioeconomic burden and cross border reproductive services for fertility preservation, 117–20 psychosocial impact of, 27–8 (CBRS), 131–2, 133 for IVF, 75–6 symptoms and signs of, 26–7, 28 cryopreservation. See also embryo laboratory procedure for, 108–9 uterine abnormalities, 33, 40 cryopreservation; oocyte embryo culture endometriosis fertility index (EFI), 24 cryopreservation buffer use in, 95–6 endometrium, luteal phase support of, ethical dilemmas in, 141–4 gas phase of, 103–5 75 gonadal tissue, 115, 117–20 in incubators, 96, 103, 104 environment, laboratory, 93–4 laboratory procedure for, 108–9 laboratory procedure for, 103–5 epidemiology of infertility, 1, 2–3, 4 ovarian tissue, 117–20 media for, 88, 105 epididymis, 48 sperm, 117, 141–4 pH of, 103 equipment, validation and verification testicular tissue, 117 embryo glue, 88 of, 162 cryostorage, 93, 120 embryo screening, 146 ERA. See endometrial receptivity array cryptorchidism, 45 embryo selection erectile dysfunction (ED), 47 CTFR. See cohort total fertility rate conventional assessment for, 105–6, eSET. See elective single embryo culture. See embryo culture 107 transfer cystectomy, 29 laboratory procedure for, 105–6, 107 ESGE. See European Society of cystic fibrosis (CF), 46, 48, 50 time lapse imaging for, 106 Gynaecological Endoscopy embryo transfer ESHRE. See European Society of Danazol, 28 catheters for, 73 Human Reproduction and data protection, 165 cleavage stage or blastocyst transfer, Embryology density centrifugation, buoyant, 97–8 74 ethical dilemmas, 136, 137, 146 diabetes, 47–8 double, 108 baby design, 146 diagnostic laparoscopy. See in IVF, 59, 62–3, 73–4 comparison of adoptive parent laparoscopy laboratory procedure for, 105, 106–8 selection to fertility treatment diagnostic test accuracy studies, 150 number of embryos transferred in, access, 138–9 diet, 25–6 74, 106–8 confidentiality, 141 DNA tests, sperm, 90 technique of, 73–4 consequentialism approach to, 138 document control system, 160–1 ultrasound use in, 73 double jeopardy risks for patients donors. See also third-party endocrine disorders. See also with co-morbidities, 140–1 reproduction hypothalamic pituitary disorders; fairness approach to, 139–40 assessment of, 129–30 ovulation disorders in fertility preservation, 120–1 168 © in this web service Cambridge University Press www.cambridge.org Cambridge University Press 978-1-108-81783-7 — Reproductive Medicine for the MRCOG Edited by Siladitya Bhattacharya , Mark Hamilton Index More Information Index in gamete cryopreservation, 141–4 patient assessment prior to, 116–17 for pituitary control in IVF, 70, 71 in gamete donation, 144–6 pregnancy outcomes in cancer gonadotropin-releasing hormone moral status of human embryos, 140 survivors, 120 analogues (GnRHa), 28, 29 in reproductive medicine versus preventative options for men, 121 gonadotropin-releasing hormone other branches of medicine, 136–7 preventative options for women, 121 (GnRH) antagonists rights-based system approaches storage options for men, 117 for fertility preservation, 118 to, 139 storage options for women, 117–20 OHSS prevention and, 77–8 welfare of potential people, 137–8, fertility rates, 1, 2–3 for pituitary control in IVF, 70–1 143, 145, 146 fertility sparing surgery, 121 gonadotropins ethical principles, 136, 137 fertility treatment access, 137–40 for endometrioma, 29 ethnicity, endometriosis risk and, 25 fibroids, uterine, 31–3,