Berkeley, CA 94720 One Cyclotron Road Laboratory Lawrence Berkeley National Earth SciencesDivision DIRECTIONS

By BART

Take the Richmond line to the downtown Berkeley exit -- not the North Berkeley exit, and not the Ashby exit, just the Berkeley exit. Get off at the Berkeley exit, go up to the street level, and find our shuttle bus stop. It is on the north side of Center Street at its intersection with Shattuck Avenue next to the bank automatic teller machine.

By LBNL Bus

You can then take the shuttle bus to the Lab. ESD Distinguished Please note, visitors are required to bring visitor bus pass (can be requested through Visitor Pass Scientist Seminar site https://visitorpass.lbl.gov/public_html/login.jsp), Series email, or permission from lab host written on department letterhead. Please contact Yingying Kooyman at 510-486-4539 or at Topic:Investigating the physical basis [email protected] for details. of Speaker: Patricia Dove By Car Tech Take Highway 80 to the University Avenue exit. 10:30 AM-12:00 noon Drive east on University Avenue until Oxford Bldg. 50 Auditorium Street. Turn left on Oxford. Go two blocks to Friday, January 15, 2010 Hearst Street. Turn right on Hearst until you hit LBNL.

Lawrence Berkeley National Laboratory

For inquiries, please contact: Caption describing picture or graphic. Yingying Kooyman 510-486-4539 Web site: http://esdnews.wordpress.com/distinguished- scientist-seminar-series/

BSTRACT IOGRAPHICAL KETCH CHEDULE A B S S The ability of organisms to mineralize Patricia M. Dove is a Professor of tissues into skeletons and other in the Department of 9:00 am functional structures is a crowning Geosciences at . After receiving achievement of biology. High- a Ph.D. at in 1991 and a Open to anyone, Earth Sciences, B90 resolution studies of biominerals are NSF Graduate Fellowship for research at revealing that many calcifying (1991-1993), she joined 10:30 am organisms do not use the classical the faculty in the School of Earth and Talk and Discussion, B50 Auditorium crystal growth process of step Atmospheric Sciences at (1993- nucleation and propagation by the 2000). At Virginia Tech, her research group terrace-ledge kink model. Rather, in the Biogeochemistry of Earth Processes 12:00 noon - 1:30 pm “Brown Bag” style lunch, Perseverance Hall, diverse phyla deploy alternative (bgep) is focused on understanding post-docs strategies involving accumulation of calcification and silicification in experimental amorphous precursor phases that and theoretical studies of mineral nucleation, transform into a crystalline material in growth and demineralization in skeletal 2:00 pm intimate association with proteins, tissues and diverse earth environments. Dove Meeting with ESD scientists, B90 polysaccharides, and other is a Fellow of the American Geophysical macromolecules. Union, Fellow of the Mineralogical Society of America, recipient of a University Best The ESD Distinguished Scientist Seminar This presentation will highlight findings from Teaching Award, the Series is a monthly seminar featuring our experimental efforts to understand factors Clarke Medal (1996), has twice been eminent individuals from various disciplines that regulate the growth of biominerals during recognized by DOE Best University Research in the scientific community whose research is outstanding, interdisciplinary, and of broad calcification and resultant compositions. I will Contributions (1998, 2005). interest to strategic interest initiatives in the begin with insights gained from our studies of earth sciences. Speakers normally spend a calcite growth by step propagation, to Continuation of Abstract: full day with researchers at Earth Sciences establish the influence of step structure and Insights from these studies suggest Division, LBNL, and the University of California, Berkeley. biomolecules on kinetics and magnesium calcification involving amorphous incorporation. The magnesium content, or intermediates could be widespread in some signature, is of particular interest because it is types of sedimentary environments, as well as widely used as a proxy for reconstructing in organisms. paleoenvironmental conditions. From this Earth Sciences Division “baseline” of behavior, I will then show that A number of long-standing enigmas Lawrence Berkeley National Laboratory calcification by a pathway involving an may be explained when viewed One Cyclotron Road, MS 90R1116 Berkeley, CA 94720 amorphous calcium carbonate phase results through the lens of calcification by this in marked increases in magnesium signatures. mineralization process. Established Phone: 510-486-4539 The shifts are correlated with the chemistry of paradigms for controls on Fax: 510-486-5686 E-mail: [email protected] the biomolecule, possibly though changes in compositional and isotopic signatures cation solvation of early clusters. in carbonate minerals may need to be revisited.