DOCSLIB.ORG

UW-Madison 2017 Education│Research│Innovation for Our Alumni, Supporters, and Friends

Total Page：16

File Type：pdf, Size：1020Kb

Download full-text PDF Read full-text
UW-Madison 2017 Education│Research│Innovation for Our Alumni, Supporters, and Friends BIOCHEMISTRY InVi o Department of Biochemistry - College of Agriculturalv and Life Sciences - UW-Madison 2017 Education│Research│Innovation For our alumni, supporters, and friends Cryo-EM Facility Coming to Biochemistry facebook.com/UWBiochem Find us online at twitter.com/UWBiochem biochem.wisc.edu linkedin.com/company/uwbiochem All are invited to join us for our upcoming Steenbock Symposium — registration is now open With questions or feedback for the department please contact: Brian Fox, Department Chair Change of Address: Department of Biochemistry Crystal M. Peterson University of Wisconsin–Madison Phone: (608) 262-3040 433 Babcock Drive Email: [email protected] Madison, WI 53706-1544 USA Alumni News: Phone: (608) 262-3040 [email protected] FAX: (608) 265-4693 Web: biochem.wisc.edu Newsletter Coordinators: Photography and Design Cover image: Cryo-EM images of fruit fly cell mitochondria, Robin Davies where the cell produces its energy. These images were Laura Vanderploeg produced at the HHMI Janelia Farm Research Campus, using technology that will soon be available at UW–Madison. Writer Images courtesy of Desirée Benefield and design by Robin Davies. Kaine Korzekwa Citation: eLife 2017;6:e25940 DOI: 10.7554/eLife.25940 2 From the Chair of images that can be obtained from and the kindness of donors to the complex biological assemblies. These department. images span many dimensions, from In this and successive issues, we cell-cell interactions to the 3-D will be honoring the achievements structures of single proteins. The of members of our community Professor Brian Fox Department of Biochemistry has by publishing degrees obtained, I am pleased to provide this brief taken the lead on campus in bringing awards won, other life events, and introduction to the new format of our this enabling new technology to the generous support provided by annual Department of Biochemistry UW–Madison, and our goal is to individuals and corporate partners. newsletter. Our goal is to keep current keep you informed and up-to-date Our department thrives on the members, alumni and friends up- on the deployment and impacts of diversity, skills and commitment of to-date on the most exciting things this exciting research opportunity at its members, alumni and friends. We happening here at UW–Madison in UW–Madison. encourage all of you to interact with our research, teaching and service to This volume of the newsletter us and look forward to receiving your the world. In these communications, also includes three alumni profiles: comments, advice and referrals as we we will be highlighting the an undergraduate, Michael Rummel, continue along this path and affirm achievements of our students, staff, B.S., ’05; a graduate student, Dr. our commitment to excellence. If you faculty and alumni, and providing Fred Porter, Ph.D., ’08; and former are able, please consider becoming information and education on where postdoctoral fellow, Dr. Amy a donor to the Department of our scientific endeavors are going, Prunuske, who was here from ’07- Biochemistry by contacting us or how our research is being carried out, ‘11. Their career paths, given in these by reaching out to the University of and the results being achieved. It is profiles, are both inspirational and Wisconsin Foundation. our sincere hope you will find these representative of the opportunities In closing, thank you for all you newsletters engaging, enlightening and outcomes our department strives do. We look forward to hearing from and inspiring. to provide. you and having you visit. Some of you will note the You will also find highlights Let us surprise you with how redesign of the cover page and the of the research from three of our things have changed since you were new name “Biochemistry In Vivo,” faculty. Professor Robert Landick last here. with its meaning “within the living” describes his studies of the structure serving as a metaphor for the amazing and function of the ribosome as Table of Contents work being carried out in the it translates mRNA into protein; From the Chair 3 department on life processes spread Professor Katherine Henzler- Cryo-EM 4 across the areas of health, energy, Wildman reports on a new way to Research News 6 the environment and many other pump antibiotics into bacteria; and Alumni Profiles 10 avenues. Professor Srivatsan (“Vatsan”) Raman Graduate Degrees 14 In this newsletter, we provide describes how designer viruses might Honors and Awards 16 an introduction to cryo-electron be deployed to kill bacteria and Letters from the Labs 19 microscopy. Recent advances coming prevent infection. These innovative In Memoriam 22 from several disciplines have led to projects proceed with extramural Donors 23 rapid improvement in the resolution research grants, institutional support, Innovation 24 3 Cryo-EM Coming to Biochemistry Facility to Serve as Resource for All of Campus tructural biology and collaboration Dubochet (University of Lausanne), the same time, build on others. Sare two strong and enduring Joachim Frank (Columbia University), To jump-start the creation and aspects of research at the University and Richard Henderson (MRC operation of the facility, Landick led an of Wisconsin–Madison. In keeping Laboratory of Molecular Biology) for effort to obtain a UW2020 grant from with this tradition, the Department of their development of the experimental the VCRGE. Desirée Benefield, a Ph.D. Biochemistry has led a concerted cross- and computational methods that scientist and expert in cryo-EM was campus effort to bring cryo-electron underpin the remarkable versatility of hired shortly thereafter. She has already microscopy (cryo-EM) to campus. this technology. been playing an integral role in the Cryo-EM has recently advanced “Cryo-EM has emerged as an facility’s success by providing guidance to a point that it can generate high- indispensable method for structural to the facility’s future users, such as resolution structures of biological analysis in the biosciences,” says training them in sample preparation, molecules by using electrons to biochemistry professor Robert Landick, imaging, and analysis. generate images. Thus, cryo-EM is one of the leaders on the project. “I’ve been working with interested a burgeoning technology that can “It is not hyperbole to say that it is researchers on campus to walk them help UW–Madison researchers make revolutionizing our understanding of through how a cryo-EM project significant new contributions to many large macromolecular machines. For develops, from sample preparation to areas of structural biology, including UW–Madison to remain a powerhouse data acquisition,” she explains. “I’ve also enzymology, virology, cell biology, and in bioscience research, it is crucial been getting resources together for new medicine. These discoveries will lead to that modern cryo-EM capabilities be users to get started on their projects. For a better understanding of many diseases brought to campus.” example, I’ve got workspace set up for and possible treatments. preparing negatively stained EM grids, Last October, the 2017 Nobel Prize Creating a new facility in Biochemistry an important start for most cryo-EM in Chemistry was awarded to Jacques A new research facility, yet to be projects. It’s been humbling to be part named, will be housed in the Hector of something that’s so important for the F. DeLuca Biochemical Sciences department and the university.” Complex, and its users will come Benefield studied biochemistry from across campus and beyond. at the University of Tennessee- Researchers are planning to use state- Chattanooga and completed her of-the-art, powerful microscopes to Ph.D. in microbiology at Vanderbilt study everything from whole cells to University. There, she learned about organelles and single enzymes. The cryo-EM and became enthralled Morgridge Institute for Research, Office with the technique. In of the Vice Chancellor for Research 2014, she came to and Graduate Education (VCRGE), UW–Madison for School of Medicine and Public postdoctoral Health, UW Carbone Cancer Center, and Departments of Biomolecular Chemistry and Neuroscience are key partners with the Department of Biochemistry in the effort to establish this multi-million-dollar facility. The facility is expected to open Cryo-EM image of reovirus T1L in 2019. Currently, the department is particles. They are displaying attachment searching for faculty members who are fibers as indicated by white arrowheads. leaders in cryo-EM research and would These viruses cause respiratory and want to join the department’s efforts. intestinal inflammation. Because of the breadth of applications Image courtesy of Rebecca S. Dillard and of cryo-EM, this will inevitably draw Elizabeth R. Wright, Emory University. the department into new areas, and at 4 training in the lab of virology professor works and how mutations change Paul Ahlquist, who aims to use the that. Knowledge of structure provides How does cryo-EM work? new facility to visualize the structure a solid foundation for the design of For experiments in cryo-EM, samples must be frozen to extremely cold associated with the replication of viruses new protein functions, enhancement of temperatures to stop the molecules responsible for Zika, MERS, SARS, pathways to make valuable bioproducts, from moving and then electron beams Dengue Fever, and Chikungunya. and improvements in many other are shot at the frozen molecules in the “Desirée’s effort is essential to bioprocesses. microscope to capture an image of its the operation of a modern cryo-EM Cryo-EM can produce detailed structure. research facility,” Landick says. “With structures needed to define the location, The biological samples are encased this project underway, we are excited to architecture, and dynamics of a wide in vitreous, or glass-like, ice; ice that have a staff member on board to anchor array of biological molecules, such as is formed so quickly that the water our efforts to establish this facility.” cellular membranes, organelles, cell-cell molecules don’t have time to become contacts, and interactions of a virus with ordered into a lattice.
Load more

Recommended publications
  • Trans Fat Free by 2023 CASE STUDIES in Trans Fat Elimination
    Trans Fat Free by 2023 CASE STUDIES in Trans Fat Elimination YEARS 2009-2019 Edited by NCD Alliance, May 2019 Cover images and page 4, 22: © shutterstock Pages 8: © stock.adobe.com Page 16: Kim Jones Page 30: © REUTERS / Finbarr O’Reilly / stock.adobe.com Page 35: Paralela NCD Alliance | 31-33 Avenue Giuseppe Motta | 1202 Geneva, Switzerland www.ncdalliance.org Table of contents Executive Summary 4 Background 4 Country-Specific Case Studies 5 Key Conclusions 6 Taking Action – What Needs to Happen 7 The NCD Alliance calls on governments to: 7 Introduction 8 Goals of the Report 8 Methodology 9 Background on Trans Fats and Policy Strategies 10 What Are TFAs? 10 Health Harms of TFA Consumption 10 World Health Organization Recommendations 11 Strategies to Reduce TFA Consumption 12 The First TFA Limit 12 Current Status of TFA Policies 12 Map of countries and territories that have enacted a TFA limit or PHO ban 14 Country-Specific Case Studies 16 Chile 16 Saudi Arabia 19 Slovenia 22 South Africa 25 Thailand 27 United States of America 29 Key Conclusions 32 Acknowledgements 36 Additional Information 38 References 39 Trans Fat Free by 2023 Case Studies in Trans Fat Elimination Executive Summary Background Industrially-produced trans fatty acids (TFAs),a This report presents case studies of six countries common in baked goods, pre-packaged foods in different regions of the world that have enacted and some cooking oils, are a major contributor to policies to eliminate TFAs from their food supply, cardiovascular diseases (CVD) and noncommunicable as recommended by WHO.4 The purpose of this diseases (NCDs) worldwide,1 estimated to contribute report is to provide civil society organisations to more than half a million deaths each year.2 TFAs (CSOs), including national and regional NCD have no known health benefits and can be replaced alliances, and policy-makers around the world with in foods without impacting their consistency or taste.
    [Show full text]
  • Letter Reso 1..5
    *LRB10013159MST27555r* SR0637 LRB100 13159 MST 27555 r 1 SENATE RESOLUTION 2 WHEREAS, The members of the Illinois Senate are saddened to 3 learn of the death of Fred August Kummerow of Urbana, who 4 passed away on May 31, 2017; and 5 WHEREAS, Fred Kummerow was born in Berlin, Germany to 6 Helene Rieck and August Kummerow on October 4, 1914, while his 7 father was away in the German Army fighting the Russians on the 8 Eastern Front; in 1923, at the age of eight, he and his family 9 emigrated to the United States; he began school in Milwaukee, 10 Wisconsin, not speaking a word of English; he graduated from 11 Boys Technical High School in Milwaukee in 1933; and 12 WHEREAS, Fred Kummerow was employed at Yahr Lange Drug & 13 Cosmetic Company, working 48-hours a week and taking night 14 classes four nights a week at the Milwaukee branch of the 15 University of Wisconsin, which was enough to make him a 16 sophomore at the University of Wisconsin-Madison when he began 17 there in September of 1936; he graduated with a Bachelor of 18 Science in Chemistry in 1939; he started his graduate work with 19 Professor Harry Steenbok, the discoverer of Vitamin D; he was 20 awarded a Master of Science in 1941 and a Ph.D. in 1943, both 21 in Biochemistry; and 22 WHEREAS, Fred Kummerow married Amy Louise Hildebrand on SR0637 -2- LRB100 13159 MST 27555 r 1 June 24, 1942; in the Fall of 1943, they left Madison for a 2 National Research Council job at Clemson University in South 3 Carolina; the job aimed to eradicate pellagra, a disease caused 4 by the lack
    [Show full text]
  • Federal Register/Vol. 78, No. 217
    Federal Register / Vol. 78, No. 217 / Friday, November 8, 2013 / Notices 67169 Brookings Institution event Web site at SUMMARY: Based on new scientific component of these oils. This document http://www.brookings.edu//health/ evidence and the findings of expert addresses PHOs because they are the events. scientific panels, the Food and Drug primary dietary source of industrially- Transcripts: Please be advised that Administration (FDA) has tentatively produced trans fat (Ref. 1). Although all transcripts will not be available. determined that partially hydrogenated refined edible oils contain some trans SUPPLEMENTARY INFORMATION: On July 9, oils (PHOs), which are the primary fat as an unintentional byproduct of 2012, the President signed into law the dietary source of industrially-produced their manufacturing process, trans fats Food and Drug Administration Safety trans fatty acids, or trans fat, are not are an integral component of PHOs and and Innovation Act (FDASIA) (Pub. L. generally recognized as safe (GRAS) for are purposely produced in these oils to 112–144). Title I of FDASIA any use in food based on current affect the properties of the oil and the reauthorizes PDUFA and provides FDA scientific evidence establishing the characteristics of the food to which they with the user fee resources necessary to health risks associated with the are added. maintain an efficient review process for consumption of trans fat, and therefore The current scientific evidence, human drug and biological products. that PHOs are food additives. Although which is discussed in section IV of this The reauthorization of PDUFA includes FDA has not listed the most commonly document, identifies significant health performance goals and procedures for used PHOs, they have been used in food risks caused by the consumption of the Agency that represent FDA’s for many years based on self- trans fat.
    [Show full text]
  • Wise Traditions
    Wise Traditions IN FOOD, FARMING AND THE HEALING ARTS A PUBLICATION OF Volume 13 Number 1 T HE W ESTON A. PRICE FOUND at ION ® Spring 2012 CONTENTS FEATURES Good Fats, Bad Fats Page 16 All Thumbs Book Reviews Page 46 Chris Masterjohn separates fact from fiction Odd Bits Tending the Wild The China Study Myth Page 23 Beyond Broccoli Denise Minger debunks the The Happiness Diet vegan conclusions The Polluters Salt and Our Health Page 28 Tim's DVD Reviews Page 52 Morton Satin, PhD, describes the folly Tim Boyd reviews great new videos of salt reduction measures Growing Wise Kids Page 55 Jen Allbritton, CN, on sustenance from soup DEPARTMENTS President’s Message Page 2 Soy Alert Page 60 Mythbusters Kaayla Daniel, PhD, on soy and the link to thyroid disease Letters Page 3 Legislative Update Page 65 Caustic Commentary Page 13 Judith McGeary on raw milk defense at the Sally Fallon Morell challenges policy level the Diet Dictocrats A Campaign for Real Milk Page 69 The Dietitian's Experience Page 39 Testimony by David Gumpert at the Kim Rodriguez, RD, takes us to a Harvard raw milk debate children's psychiatric hospital Raw Milk Updates Page 72 Healthy Baby Gallery Page 76 Homeopathy Journal Page 43 Local Chapters Page 79 Joette Calabrese describes treatments Shop Heard ‘Round the World Page 92 for urinary tract infections Membership Page 116 Upcoming Events Page 117 89494_text.indd 1 3/19/12 11:36 AM THE WESTON A. PRICE President’s Message FOUNDatION ® Education Research Activism BOARD OF DIRECTORS Sally Fallon Morell, MA, President and Treasurer Kaayla T.
    [Show full text]
  • [Docket No. FDA-2013-N-1317] Final Determination
    This document is scheduled to be published in the Federal Register on 06/17/2015 and available online at http://federalregister.gov/a/2015-14883, and on FDsys.gov 4164-01-P DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No. FDA-2013-N-1317] Final Determination Regarding Partially Hydrogenated Oils AGENCY: Food and Drug Administration, HHS. ACTION: Notice; declaratory order. SUMMARY: Based on the available scientific evidence and the findings of expert scientific panels, the Food and Drug Administration (FDA or we) has made a final determination that there is no longer a consensus among qualified experts that partially hydrogenated oils (PHOs), which are the primary dietary source of industrially-produced trans fatty acids (IP-TFA) are generally recognized as safe (GRAS) for any use in human food. This action responds, in part, to citizen petitions we received, and we base our determination on available scientific evidence and the findings of expert scientific panels establishing the health risks associated with the consumption of trans fat. DATES: Compliance date: Affected persons must comply no later than June 18, 2018. FOR FURTHER INFORMATION CONTACT: Mical Honigfort, Center for Food Safety and Applied Nutrition (HFS-265), Food and Drug Administration, 5100 Paint Branch Pkwy., College Park, MD 20740, 240-402-1278, email: [email protected]. SUPPLEMENTARY INFORMATION: Table of Contents 2 I. Background II. Definitions and Scope, and Related Comments With FDA Responses III. Discussion of Legal Issues, and Related Comments With FDA Responses A. GRAS B. Prior Sanctions C. Procedural Requirements IV. Discussion of Scientific Issues, and Related Comments With FDA Responses A.
    [Show full text]
  • Proposed FDA Rule to Ban Partially Hydrogenated Vegetable Oils
    Proposed FDA Rule To Ban Partially Hydrogenated (PHO) Oils Johari Minal [email protected] Outline • Chronology of events • The harmful effects of trans fats • The alternatives Background • 1957 – Fred Kummerow published paper against trans fats • 1968 – Asked AHA and ISEO to reduce trans fats • November 17, 1999 FDA proposed rule on “Food Labeling: Trans Fatty Acids in Nutrition Labeling, Nutrient Content Claims, and Health Claims • July 11, 2003 FDA issued a final rule on nutrition labeling regulations to require declaration of the trans fatty acid content, effective Jan 1, 2006 • 2004 - CSPI requested FDA to revoke the GRAS status of PHOs • August 28, 2009 Fred Kummerow filed a petition to FDA to ban trans fat • November 7, 2013, the US Food and Drug Administration (FDA) announced it is now considering removing partially hydrogenated oils (PHO)—the primary source of trans fats—from the list of “generally recognized as safe” (GRAS) ingredients. • Became globals news • If finalized, this would mean that food manufacturers would no longer be permitted to sell PHOs, either directly or as ingredients in another food product, without prior FDA approval for use as a food additive. Adverse Effects of Trans Fatty Acids PHOs could be harmful (i.e., increased risk for there is no threshold intake level for CHD) under any condition of use in food industrially-produced trans fat that would not increase an individual's risk of CHD risk factors for CHD - increased LDL-C levels and stronger effect on the risk of CHD than an increased risk of CHD
    [Show full text]
  • The Additive Effect of Additives Presented By
    The Additive Effect of Additives Presented by: Betsy Reynolds, RDH, MS Agenda Introduction Why Additives Are Added Overview of Common Additives Headliners Close Food additives are substances that become part of a food product when added (intentionally or unintentionally) during the processing or production of that food Food additives serve FIVE main functions: Maintain product consistency Improve or preserve the nutrient value Maintain the ‘wholesomeness’ of foods Control the acidity and alkalinity, and to provide leavening Provide color and ‘enhance’ flavor Certain colors ‘improve’ the appearance of foods There are many spices and natural and synthetic flavors that bring out the ‘best’ in the flavor of food Almost 100% of all farmed salmon is artificially colored with either canthaxanthin or astaxanthin—a process sometimes euphemistically called 'color finishing' Swiss chemical giant Hoffman La Roche synthetically produces canthaxanthin and an astaxanthin from petrochemicals and provides customers with its SalmoFan—to help salmon farmers and buyers create and/or order a color that sells well Color isn’t the only additive: Pesticides fed to farmed fish and toxic copper sulfate used to keep nets free of algae are building up in sea-floor sediments Antibiotics have created resistant strains of disease that infect both wild and domesticated fish Clouds of sea lice, incubated by captive fish on farms, swarm wild salmon as they swim past on their migration to the ocean An ‘added’ concern: Of all the concerns, the biggest turns out
    [Show full text]
  • 1 Box List: Fred August Kummerow Papers Veterinary Medicine, UIUC ID: 17/5/21
    1 Box List: Fred August Kummerow Papers Veterinary Medicine, UIUC ID: 17/5/21 Arrangement: Series 1: Correspondence File, 1941-2014 Series 2: Personal Materials, 1932-2017 Series 3: Student and Post-Doc Files, 1948-2005 Series 4: Grant Files, 1950-2004 Series 5: Research Materials, 1946-87 Series 6: Course Materials, 1949-71 Series 7: Patent Files, 1953-65 Series 8: Federal Trade Commission (FTC) Files, 1965-87 Series 9: Conferences, Speeches, and Presentations, 1947-98 Series 10: Kummerow Reviews of Other Researchers’ Papers, 1975-2003 Series 11: Papers, 1939-2016 Series 12: Reprint Requests, 1950-98 Complete Finding Aid: https://archives.library.illinois.edu/archon/index.php?p=collections/controlcard&id=11456&q=kummerow Box list created 2017-05-26 Repository: University Archives University of Illinois at Urbana-Champaign http://archives.library.illinois.edu/ Series 1: Correspondence File, 1941-2014 Consists of correspondence, memoranda, minutes, and reports relating to Fred A. Kummerow’s research on fatty acids, lipids, cholesterol, trans fats, oxidized sterols, cell membranes, hydrogenation, oxidation, arteriosclerosis, atherosclerosis, pellagra, vitamins, nutrition, food storage, eggs, edible oils, sorghum, and wheat germ. Includes material on the Burnsides Research Laboratory and the Harlan E. Moore Research Foundation. This series is organized into three sub-series—Personal Correspondence, General Correspondence, and University of Illinois Correspondence—that are arranged in alphabetical order. For additional correspondence see Boxes 70 - 72. Box 1 Personal Correspondence 1. Personal correspondence, 1941-45 2. Personal correspondence, 1949-69 3. Resignation, Letters and Related Material, 1947-50 General Correspondence 4. Academic Press Inc. [Empty] 5. ACH Food–Oscar Washington [Empty] 6.
    [Show full text]
  • Trans-Fats. Partial Hydrogenation the World Is Watching the US FDA
    World Nutrition Volume 5, Number 3, March 2014 WN Feedback World Nutrition Volume 5, Number 3, March 2014 Journal of the World Public Health Nutrition Association Published monthly at www.wphna.org/worldnutrition/ Trans-fats. Partial hydrogenation The world is watching the US FDA Access February 2014 Geoffrey Cannon Inspiration on Fred Kummerow here Access February 2014 Fred Kummerow Feedback letter here Fred Kummerow, the man in blue (left), is sueing the US FDA, specifically the women with the red background (right), Margaret Hamburg and her boss in the Obama cabinet Kathleen Sebelius From Fred A Kummerow: The US Food and Drug Administration has given the food manufacturing industry another 60 days to respond to their intention to withdraw the classification ‘generally recognised as safe’ from trans-fats. The comment period that was scheduled to end 7 January 2014 has been extended to 8 March at 11:59 pm, US East Coast time. If and when this action is at last taken, trans-fats will in due course effectively be eliminated from the US food supply. As stated in my previous WN letter, last August I filed a lawsuit against the US Food and Drug Administration (1,2), specifically addressing FDA commissioner Margaret Hamburg and her boss the Department of Health and Human Services secretary Kathleen Sebelius (right hand picture, above). This states that the FDA’s failure to ban the use of partially hydrogenated oils containing artificial trans fat in food for human consumption, is unlawful. This is not a matter for the food product manufacturing industry. The prime duty of the FDA is to protect public health.
    [Show full text]
  • Federal Register/Vol. 80, No. 116/Wednesday, June 17, 2015
    34650 Federal Register / Vol. 80, No. 116 / Wednesday, June 17, 2015 / Notices Seven PREIS grantees have requested Objectives and Need for Assistance, Single-source program expansion supplemental funding awards. Their Approach, and Budget and Budget supplement awards are made to the applications were assessed by a review Justification. The applications were following PREIS grantees: panel for completeness and assessed to have scored within a responsiveness in the categories of fundable range. Supplement award Grantee organization City State amount Child and Family Resources, Inc. ......................................................... Tucson ........................................... AZ $32,314 Children’s Hospital of Los Angeles ....................................................... Los Angeles ................................... CA 115,898 Cicatelli Associates Inc. ......................................................................... New York ....................................... NY 130,000 Demoiselle2Femme ............................................................................... Chicago ......................................... IL 55,959 Education Development Center, Inc. ..................................................... Newton .......................................... MA 55,560 Teen Outreach Pregnancy Services ..................................................... Tucson ........................................... AZ 29,000 The Village for Families & Children, Inc ...............................................
    [Show full text]
  • Vegetable Oils: the UNKNOWN STORY
    Vegetable Oils: THE UNKNOWN STORY BY, NINA TEICHOLZ SCIENCE JOURNALIST, AUTHOR, THE BIG FAT SURPRISE © Nina Teicholz Polyunsaturated Vegetable Oils • Corn oil • Cottonseed oil • Soybean oil • Safflower oil • Peanut oil • Canola oil © Nina Teicholz The original, natural fats Tallow Suet © Nina Teicholz *Lard* *Butter* © Nina Teicholz Oils used as lubricants for machinery in industrial revolution © Nina Teicholz Cottonseed oil © Nina Teicholz Chemistry of fatty acids © Nina Teicholz Hydrogenation © Nina Teicholz Process of Hydrogenation Pressure, heat, hexane (solvent) + a metal catalyst. Resulting rancid mixture must be steamed to eliminate bad odors, bleached to remove the gray color, “winterized” for stability and then enhanced artificial colors and synthetic vitamins © Nina Teicholz The marketing of Crisco © Nina Teicholz Margarine © Nina Teicholz Vegetable cooking oils © Nina Teicholz Procter & Gamble and the American Heart Association 1948. $1,740,000, or 17 million in today’s dollars. “suddenly the coffers were filled…. It was the “bang of big bucks” that “launched” the group. Source: Big Fat Surprise, pp. 47-48 © Nina Teicholz 1961: American Heart Association recommends polyunsaturated oil to fight heart disease © Nina Teicholz The American Heart Association recommends vegetable oils © Nina Teicholz Ancel Keys and the “Diet-Heart” hypothesis © Nina Teicholz © Nina Teicholz © Nina Teicholz Distributed free of charge to thousands of doctors. Inside, Jerry Stamler thanks The Corny Products Co. and the Wesson Fund for Medical Research for “significant” research support. Stamler in an interview: “Scientists in public health must make alliances with industry…it’s tough. © Nina Teicholz Polyunsaturated fats as medicine © Nina Teicholz Testing the “diet heart hypothesis” • There were actually a large number of government- funded, randomized, controlled clinical trials….
    [Show full text]
  • Milk Phospholipids a New Ingredient for Formulation of Functional Foods with Bioactivity
    inform August 2009 www.aocs.org Volume 20 (8) 489–552Volume International News on Fats, Oils, and Related Materials ALSO INSIDE: Message from AOCS’ President Taking another look at global oil yields Annual Meeting award addresses Milk phospholipids A new ingredient for formulation of functional foods with bioactivity www.aocs.org !UGUST 6OLUME n Departments Milk phospholipids and Information (ANS "URLING ±KE .ILSSON AND ,ENA /HLSSON EXAMINE A NEW ingredient from milk for formulation of functional foods with 490 Index to Advertisers bioactivity. 490 Calendar Global oil yields: Have we got it seriously wrong? 493 Message from the Denis J. Murphy details recent research that calls into question the President assumptions surrounding global oil yields and the part they have to play in biofuels and food production. Marketplace: Omega-3 fatty acid profiling and dietary forensics 505 News & Noteworthy Ken D. Stark presents his AOCS Young Scientist Research Award 511 Biofuels News !DDRESS DELIVERED AT THE TH !/#3 !NNUAL -EETING %XPO HELD IN /RLANDO &LORIDA 53! -AY n 517 Health & Nutrition News Minutes for the 2009 AOCS business meeting 521 Biotechnology News Emerging research in insect lipids 525 S&D News Brent Sørensen presents a field of research that remains relatively 529 People News/ unexplored. Inside AOCS Regiospecific quantification of triacylglycerols in castor oil containing ricinoleate and dihydroxy 503 Classified Advertising fatty acids by mass spectrometry *IANN 4SYH +EN ,IN PRESENTS HIS (ERBERT * $UTTON !WARD 510 Classified Advertising
    [Show full text]