PDSS1 Antibody Cat. No.: 26-108

PDSS1 Antibody

Specifications

HOST SPECIES: Rabbit

SPECIES REACTIVITY: Human, Mouse

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region IMMUNOGEN: of human PDSS1.

TESTED APPLICATIONS: ELISA, WB

PDSS1 antibody can be used for detection of PDSS1 by ELISA at 1:12500. PDSS1 antibody APPLICATIONS: can be used for detection of PDSS1 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

POSITIVE CONTROL: 1) Cat. No. XBL-10407 - Fetal Heart Tissue Lysate

PREDICTED MOLECULAR 46 kDa WEIGHT:

Properties

PURIFICATION: Antibody is purified by peptide affinity chromatography method.

CLONALITY: Polyclonal

CONJUGATE: Unconjugated

PHYSICAL STATE: Liquid

September 29, 2021 1 https://www.prosci-inc.com/pdss1-antibody-26-108.html Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% BUFFER: sucrose.

CONCENTRATION: batch dependent

For short periods of storage (days) store at 4˚C. For longer periods of storage, store STORAGE CONDITIONS: PDSS1 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.

Additional Info

OFFICIAL SYMBOL: PDSS1

ALTERNATE NAMES: PDSS1, COQ1, MGC70953, RP13-16H11.3, TPRT, TPT, hDPS1, DPS, SPS, TPT 1, COQ10D2

ACCESSION NO.: NP_055132

PROTEIN GI NO.: 50659086

GENE ID: 23590

USER NOTE: Optimal dilutions for each application to be determined by the researcher.

Background and References

PDSS1 is an that elongates the prenyl side-chain of coenzyme Q, or ubiquinone, one of the key elements in the respiratory chain. PDSS1 catalyzes the formation of all trans-polyprenyl pyrophosphates from isopentyl diphosphate in the assembly of polyisoprenoid side chains, the first step in coenzyme Q biosynthesis. The protein may be peripherally associated with the inner mitochondrial membrane, though no transit peptide has been definitively identified to date. Defects in PDSS1 are a cause of deficiency.The protein encoded by this gene is an enzyme that elongates BACKGROUND: the prenyl side-chain of coenzyme Q, or ubiquinone, one of the key elements in the respiratory chain. The gene product catalyzes the formation of all trans-polyprenyl pyrophosphates from isopentyl diphosphate in the assembly of polyisoprenoid side chains, the first step in coenzyme Q biosynthesis. The protein may be peripherally associated with the inner mitochondrial membrane, though no transit peptide has been definitively identified to date. Defects in this gene are a cause of .

REFERENCES: 1) Mollet, J., (2007) J. Clin. Invest. 117 (3), 765-772.

ANTIBODIES FOR RESEARCH USE ONLY.

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