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Print Special Issue Flyer IMPACT FACTOR 5.923 an Open Access Journal by MDPI Direct Genetic Conversion of Glia Cells to Neurons Guest Editor: Message from the Guest Editor Dr. Aurel Popa-Wagner Aer cerebral ischemia, the ratio between astroglial cells Department of Molecular and neurons in the neurovascular unit is disrupted in the Medicine, University of Medicine perilesional area. Restoring the balance within the and Pharmacy Craiova, Brisbane, QLD 4000, Romania neurovascular unit may lead to an improved [email protected] neurorestoration aer focal ischemia. Following cerebral ischemia, proliferating glia become reactive and build up a second barrier to regeneration—known as the glial scar. Although it initially provides protection by confining the Deadline for manuscript damaged area, in the long-term, the glial scar is acting as a submissions: closed (31 July 2021) physical and chemical barrier to neural regeneration by secretion of inflammatory cytokines, such as TNF-α and IL- 1β, and accumulation of neurite inhibitory factors, such as lipocalin-2. Direct astroglial reprogramming to neurons using viral vectors that carry transcription factors, such as Sox2 or Ascl1, provides a completely new strategy for neurorestoration aer stroke and other traumatic brain injuries. Therefore, in this Special Issue, we invite groups working on genetic conversion of glia cells to share their experience with the scholars of brain injuries in an attempt to find new therapeutic options for neurorestoration aer injuries to the brain. mdpi.com/si/73218 SpeciaIslsue IMPACT FACTOR 5.923 an Open Access Journal by MDPI Editor-in-Chief Message from the Editor-in-Chief Prof. Dr. Maurizio Battino The International Journal of Molecular Sciences (IJMS, 1. Department of ISSN 1422-0067) is an open access journal, which was Odontostomatologic and established in 2000. The journal aims to provide a forum Specialized Clinical Sciences, Sez-Biochimica, Faculty of for scholarly research on a range of topics, including Medicine, Università Politecnica biochemistry, molecular and cell biology, molecular delle Marche, Via Ranieri 65, biophysics, molecular medicine, and all aspects of 60100 Ancona, Italy molecular research in chemistry. IJMS publishes both 2. International Research Center for Food Nutrition and Safety, original research and review articles, and regularly Jiangsu University, Zhenjiang publishes special issues to highlight advances at the 212013, China cutting edge of research. We invite you to read recent articles published in IJMS and consider publishing your next paper with us. Author Benefits Open Access:— free for readers, with article processing charges (APC) paid by authors or their institutions. High Visibility: indexed within Scopus, SCIE (Web of Science), PubMed, PMC, MEDLINE, Embase, CAPlus / SciFinder, and many other databases. Journal Rank: JCR - Q1 (Biochemistry & Molecular Biology) / CiteScore - Q1 (Inorganic Chemistry) Contact Us International Journal of Molecular Tel: +41 61 683 77 34 mdpi.com/journal/ijms Sciences Fax: +41 61 302 89 18 [email protected] MDPI, St. Alban-Anlage 66 www.mdpi.com @IJMS_MDPI 4052 Basel, Switzerland.
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