Null Hypothesis
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												  Hypothesis Testing and Likelihood Ratio TestsHypottthesiiis tttestttiiing and llliiikellliiihood ratttiiio tttesttts Y We will adopt the following model for observed data. The distribution of Y = (Y1, ..., Yn) is parameter considered known except for some paramett er ç, which may be a vector ç = (ç1, ..., çk); ç“Ç, the paramettter space. The parameter space will usually be an open set. If Y is a continuous random variable, its probabiiillliiittty densiiittty functttiiion (pdf) will de denoted f(yy;ç) . If Y is y probability mass function y Y y discrete then f(yy;ç) represents the probabii ll ii tt y mass functt ii on (pmf); f(yy;ç) = Pç(YY=yy). A stttatttiiistttiiicalll hypottthesiiis is a statement about the value of ç. We are interested in testing the null hypothesis H0: ç“Ç0 versus the alternative hypothesis H1: ç“Ç1. Where Ç0 and Ç1 ¶ Ç. hypothesis test Naturally Ç0 § Ç1 = ∅, but we need not have Ç0 ∞ Ç1 = Ç. A hypott hesii s tt estt is a procedure critical region for deciding between H0 and H1 based on the sample data. It is equivalent to a crii tt ii call regii on: a critical region is a set C ¶ Rn y such that if y = (y1, ..., yn) “ C, H0 is rejected. Typically C is expressed in terms of the value of some tttesttt stttatttiiistttiiic, a function of the sample data. For µ example, we might have C = {(y , ..., y ): y – 0 ≥ 3.324}. The number 3.324 here is called a 1 n s/ n µ criiitttiiicalll valllue of the test statistic Y – 0 . S/ n If y“C but ç“Ç 0, we have committed a Type I error.
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												  Image Segmentation Based on Histogram Analysis Utilizing the Cloud ModelComputers and Mathematics with Applications 62 (2011) 2824–2833 Contents lists available at SciVerse ScienceDirect Computers and Mathematics with Applications journal homepage: www.elsevier.com/locate/camwa Image segmentation based on histogram analysis utilizing the cloud model Kun Qin a,∗, Kai Xu a, Feilong Liu b, Deyi Li c a School of Remote Sensing Information Engineering, Wuhan University, Wuhan, 430079, China b Bahee International, Pleasant Hill, CA 94523, USA c Beijing Institute of Electronic System Engineering, Beijing, 100039, China article info a b s t r a c t Keywords: Both the cloud model and type-2 fuzzy sets deal with the uncertainty of membership Image segmentation which traditional type-1 fuzzy sets do not consider. Type-2 fuzzy sets consider the Histogram analysis fuzziness of the membership degrees. The cloud model considers fuzziness, randomness, Cloud model Type-2 fuzzy sets and the association between them. Based on the cloud model, the paper proposes an Probability to possibility transformations image segmentation approach which considers the fuzziness and randomness in histogram analysis. For the proposed method, first, the image histogram is generated. Second, the histogram is transformed into discrete concepts expressed by cloud models. Finally, the image is segmented into corresponding regions based on these cloud models. Segmentation experiments by images with bimodal and multimodal histograms are used to compare the proposed method with some related segmentation methods, including Otsu threshold, type-2 fuzzy threshold, fuzzy C-means clustering, and Gaussian mixture models. The comparison experiments validate the proposed method. ' 2011 Elsevier Ltd. All rights reserved. 1. Introduction In order to deal with the uncertainty of image segmentation, fuzzy sets were introduced into the field of image segmentation, and some methods were proposed in the literature.
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												  Permutation TestsPermutation tests Ken Rice Thomas Lumley UW Biostatistics Seattle, June 2008 Overview • Permutation tests • A mean • Smallest p-value across multiple models • Cautionary notes Testing In testing a null hypothesis we need a test statistic that will have different values under the null hypothesis and the alternatives we care about (eg a relative risk of diabetes) We then need to compute the sampling distribution of the test statistic when the null hypothesis is true. For some test statistics and some null hypotheses this can be done analytically. The p- value for the is the probability that the test statistic would be at least as extreme as we observed, if the null hypothesis is true. A permutation test gives a simple way to compute the sampling distribution for any test statistic, under the strong null hypothesis that a set of genetic variants has absolutely no effect on the outcome. Permutations To estimate the sampling distribution of the test statistic we need many samples generated under the strong null hypothesis. If the null hypothesis is true, changing the exposure would have no effect on the outcome. By randomly shuffling the exposures we can make up as many data sets as we like. If the null hypothesis is true the shuffled data sets should look like the real data, otherwise they should look different from the real data. The ranking of the real test statistic among the shuffled test statistics gives a p-value Example: null is true Data Shuffling outcomes Shuffling outcomes (ordered) gender outcome gender outcome gender outcome Example: null is false Data Shuffling outcomes Shuffling outcomes (ordered) gender outcome gender outcome gender outcome Means Our first example is a difference in mean outcome in a dominant model for a single SNP ## make up some `true' data carrier<-rep(c(0,1), c(100,200)) null.y<-rnorm(300) alt.y<-rnorm(300, mean=carrier/2) In this case we know from theory the distribution of a difference in means and we could just do a t-test.
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												  This Is Dr. Chumney. the Focus of This Lecture Is Hypothesis Testing –Both What It Is, How Hypothesis Tests Are Used, and How to Conduct Hypothesis TestsTRANSCRIPT: This is Dr. Chumney. The focus of this lecture is hypothesis testing –both what it is, how hypothesis tests are used, and how to conduct hypothesis tests. 1 TRANSCRIPT: In this lecture, we will talk about both theoretical and applied concepts related to hypothesis testing. 2 TRANSCRIPT: Let’s being the lecture with a summary of the logic process that underlies hypothesis testing. 3 TRANSCRIPT: It is often impossible or otherwise not feasible to collect data on every individual within a population. Therefore, researchers rely on samples to help answer questions about populations. Hypothesis testing is a statistical procedure that allows researchers to use sample data to draw inferences about the population of interest. Hypothesis testing is one of the most commonly used inferential procedures. Hypothesis testing will combine many of the concepts we have already covered, including z‐scores, probability, and the distribution of sample means. To conduct a hypothesis test, we first state a hypothesis about a population, predict the characteristics of a sample of that population (that is, we predict that a sample will be representative of the population), obtain a sample, then collect data from that sample and analyze the data to see if it is consistent with our hypotheses. 4 TRANSCRIPT: The process of hypothesis testing begins by stating a hypothesis about the unknown population. Actually we state two opposing hypotheses. The first hypothesis we state –the most important one –is the null hypothesis. The null hypothesis states that the treatment has no effect. In general the null hypothesis states that there is no change, no difference, no effect, and otherwise no relationship between the independent and dependent variables.
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												  The Scientific Method: Hypothesis Testing and Experimental DesignAppendix I The Scientific Method The study of science is different from other disciplines in many ways. Perhaps the most important aspect of “hard” science is its adherence to the principle of the scientific method: the posing of questions and the use of rigorous methods to answer those questions. I. Our Friend, the Null Hypothesis As a science major, you are probably no stranger to curiosity. It is the beginning of all scientific discovery. As you walk through the campus arboretum, you might wonder, “Why are trees green?” As you observe your peers in social groups at the cafeteria, you might ask yourself, “What subtle kinds of body language are those people using to communicate?” As you read an article about a new drug which promises to be an effective treatment for male pattern baldness, you think, “But how do they know it will work?” Asking such questions is the first step towards hypothesis formation. A scientific investigator does not begin the study of a biological phenomenon in a vacuum. If an investigator observes something interesting, s/he first asks a question about it, and then uses inductive reasoning (from the specific to the general) to generate an hypothesis based upon a logical set of expectations. To test the hypothesis, the investigator systematically collects data, either with field observations or a series of carefully designed experiments. By analyzing the data, the investigator uses deductive reasoning (from the general to the specific) to state a second hypothesis (it may be the same as or different from the original) about the observations.
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												  Hypothesis Testing – Examples and Case StudiesHypothesis Testing – Chapter 23 Examples and Case Studies Copyright ©2005 Brooks/Cole, a division of Thomson Learning, Inc. 23.1 How Hypothesis Tests Are Reported in the News 1. Determine the null hypothesis and the alternative hypothesis. 2. Collect and summarize the data into a test statistic. 3. Use the test statistic to determine the p-value. 4. The result is statistically significant if the p-value is less than or equal to the level of significance. Often media only presents results of step 4. Copyright ©2005 Brooks/Cole, a division of Thomson Learning, Inc. 2 23.2 Testing Hypotheses About Proportions and Means If the null and alternative hypotheses are expressed in terms of a population proportion, mean, or difference between two means and if the sample sizes are large … … the test statistic is simply the corresponding standardized score computed assuming the null hypothesis is true; and the p-value is found from a table of percentiles for standardized scores. Copyright ©2005 Brooks/Cole, a division of Thomson Learning, Inc. 3 Example 2: Weight Loss for Diet vs Exercise Did dieters lose more fat than the exercisers? Diet Only: sample mean = 5.9 kg sample standard deviation = 4.1 kg sample size = n = 42 standard error = SEM1 = 4.1/ √42 = 0.633 Exercise Only: sample mean = 4.1 kg sample standard deviation = 3.7 kg sample size = n = 47 standard error = SEM2 = 3.7/ √47 = 0.540 measure of variability = [(0.633)2 + (0.540)2] = 0.83 Copyright ©2005 Brooks/Cole, a division of Thomson Learning, Inc. 4 Example 2: Weight Loss for Diet vs Exercise Step 1.
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												  Shinyitemanalysis for Psychometric Training and to Enforce Routine Analysis of Educational TestsShinyItemAnalysis for Psychometric Training and to Enforce Routine Analysis of Educational Tests Patrícia Martinková Dept. of Statistical Modelling, Institute of Computer Science, Czech Academy of Sciences College of Education, Charles University in Prague R meetup Warsaw, May 24, 2018 R meetup Warsaw, 2018 1/35 Introduction ShinyItemAnalysis Teaching psychometrics Routine analysis of tests Discussion Announcement 1: Save the date for Psychoco 2019! International Workshop on Psychometric Computing Psychoco 2019 February 21 - 22, 2019 Charles University & Czech Academy of Sciences, Prague www.psychoco.org Since 2008, the international Psychoco workshops aim at bringing together researchers working on modern techniques for the analysis of data from psychology and the social sciences (especially in R). Patrícia Martinková ShinyItemAnalysis for Psychometric Training and Test Validation R meetup Warsaw, 2018 2/35 Introduction ShinyItemAnalysis Teaching psychometrics Routine analysis of tests Discussion Announcement 2: Job offers Job offers at Institute of Computer Science: CAS-ICS Postdoctoral position (deadline: August 30) ICS Doctoral position (deadline: June 30) ICS Fellowship for junior researchers (deadline: June 30) ... further possibilities to participate on grants E-mail at [email protected] if interested in position in the area of Computational psychometrics Interdisciplinary statistics Other related disciplines Patrícia Martinková ShinyItemAnalysis for Psychometric Training and Test Validation R meetup Warsaw, 2018 3/35 Outline 1. Introduction 2. ShinyItemAnalysis 3. Teaching psychometrics 4. Routine analysis of tests 5. Discussion Introduction ShinyItemAnalysis Teaching psychometrics Routine analysis of tests Discussion Motivation To teach psychometric concepts and methods Graduate courses "IRT models", "Selected topics in psychometrics" Workshops for admission test developers Active learning approach w/ hands-on examples To enforce routine analyses of educational tests Admission tests to Czech Universities Physiology concept inventories ..
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												  Lecture 8 Sample Mean and Variance, Histogram, Empirical Distribution Function Sample Mean and VarianceLecture 8 Sample Mean and Variance, Histogram, Empirical Distribution Function Sample Mean and Variance Consider a random sample , where is the = , , … sample size (number of elements in ). Then, the sample mean is given by 1 = . Sample Mean and Variance The sample mean is an unbiased estimator of the expected value of a random variable the sample is generated from: . The sample mean is the sample statistic, and is itself a random variable. Sample Mean and Variance In many practical situations, the true variance of a population is not known a priori and must be computed somehow. When dealing with extremely large populations, it is not possible to count every object in the population, so the computation must be performed on a sample of the population. Sample Mean and Variance Sample variance can also be applied to the estimation of the variance of a continuous distribution from a sample of that distribution. Sample Mean and Variance Consider a random sample of size . Then, = , , … we can define the sample variance as 1 = − , where is the sample mean. Sample Mean and Variance However, gives an estimate of the population variance that is biased by a factor of . For this reason, is referred to as the biased sample variance . Correcting for this bias yields the unbiased sample variance : 1 = = − . − 1 − 1 Sample Mean and Variance While is an unbiased estimator for the variance, is still a biased estimator for the standard deviation, though markedly less biased than the uncorrected sample standard deviation . This estimator is commonly used and generally known simply as the "sample standard deviation".
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												  Tests of Hypotheses Using StatisticsTests of Hypotheses Using Statistics Adam Massey¤and Steven J. Millery Mathematics Department Brown University Providence, RI 02912 Abstract We present the various methods of hypothesis testing that one typically encounters in a mathematical statistics course. The focus will be on conditions for using each test, the hypothesis tested by each test, and the appropriate (and inappropriate) ways of using each test. We conclude by summarizing the di®erent tests (what conditions must be met to use them, what the test statistic is, and what the critical region is). Contents 1 Types of Hypotheses and Test Statistics 2 1.1 Introduction . 2 1.2 Types of Hypotheses . 3 1.3 Types of Statistics . 3 2 z-Tests and t-Tests 5 2.1 Testing Means I: Large Sample Size or Known Variance . 5 2.2 Testing Means II: Small Sample Size and Unknown Variance . 9 3 Testing the Variance 12 4 Testing Proportions 13 4.1 Testing Proportions I: One Proportion . 13 4.2 Testing Proportions II: K Proportions . 15 4.3 Testing r £ c Contingency Tables . 17 4.4 Incomplete r £ c Contingency Tables Tables . 18 5 Normal Regression Analysis 19 6 Non-parametric Tests 21 6.1 Tests of Signs . 21 6.2 Tests of Ranked Signs . 22 6.3 Tests Based on Runs . 23 ¤E-mail: [email protected] yE-mail: [email protected] 1 7 Summary 26 7.1 z-tests . 26 7.2 t-tests . 27 7.3 Tests comparing means . 27 7.4 Variance Test . 28 7.5 Proportions . 28 7.6 Contingency Tables .
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												  Understanding Statistical Hypothesis Testing: the Logic of Statistical InferenceReview Understanding Statistical Hypothesis Testing: The Logic of Statistical Inference Frank Emmert-Streib 1,2,* and Matthias Dehmer 3,4,5 1 Predictive Society and Data Analytics Lab, Faculty of Information Technology and Communication Sciences, Tampere University, 33100 Tampere, Finland 2 Institute of Biosciences and Medical Technology, Tampere University, 33520 Tampere, Finland 3 Institute for Intelligent Production, Faculty for Management, University of Applied Sciences Upper Austria, Steyr Campus, 4040 Steyr, Austria 4 Department of Mechatronics and Biomedical Computer Science, University for Health Sciences, Medical Informatics and Technology (UMIT), 6060 Hall, Tyrol, Austria 5 College of Computer and Control Engineering, Nankai University, Tianjin 300000, China * Correspondence: [email protected]; Tel.: +358-50-301-5353 Received: 27 July 2019; Accepted: 9 August 2019; Published: 12 August 2019 Abstract: Statistical hypothesis testing is among the most misunderstood quantitative analysis methods from data science. Despite its seeming simplicity, it has complex interdependencies between its procedural components. In this paper, we discuss the underlying logic behind statistical hypothesis testing, the formal meaning of its components and their connections. Our presentation is applicable to all statistical hypothesis tests as generic backbone and, hence, useful across all application domains in data science and artificial intelligence. Keywords: hypothesis testing; machine learning; statistics; data science; statistical inference 1. Introduction We are living in an era that is characterized by the availability of big data. In order to emphasize the importance of this, data have been called the ‘oil of the 21st Century’ [1]. However, for dealing with the challenges posed by such data, advanced analysis methods are needed.
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												  Unit 23: Control ChartsUnit 23: Control Charts Prerequisites Unit 22, Sampling Distributions, is a prerequisite for this unit. Students need to have an understanding of the sampling distribution of the sample mean. Students should be familiar with normal distributions and the 68-95-99.7% Rule (Unit 7: Normal Curves, and Unit 8: Normal Calculations). They should know how to calculate sample means (Unit 4: Measures of Center). Additional Topic Coverage Additional coverage of this topic can be found in The Basic Practice of Statistics, Chapter 27, Statistical Process Control. Activity Description This activity should be used at the end of the unit and could serve as an assessment of x charts. For this activity students will use the Control Chart tool from the Interactive Tools menu. Students can either work individually or in pairs. Materials Access to the Control Chart tool. Graph paper (optional). For the Control Chart tool, students select a mean and standard deviation for the process (from when the process is in control), and then decide on a sample size. After students have determined and entered correct values for the upper and lower control limits, the Control Chart tool will draw the reference lines on the control chart. (Remind students to enter the values for the upper and lower control limits to four decimals.) At that point, students can use the Control Chart tool to generate sample data, compute the sample mean, and then plot the mean Unit 23: Control Charts | Faculty Guide | Page 1 against the sample number. After each sample mean has been plotted, students must decide either that the process is in control and thus should be allowed to continue or that the process is out of control and should be stopped.
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												  What Determines Which Numerical Measures of Center and Spread AreQuiz 1 12pm Class Question: What determines which numerical measures of center and spread are appropriate for describing a given distribution of a quantitative variable? Which measures will you use in each case? Here are your answers in random order. See my comments. it must include a graphical display. A histogram would be a good method to give an appropriate description of a quantitative value. This does not answer the question. For the quantative variable, the "average" must make sense. The values of the variables are numbers and one value is larger than the other. This does not answer the question. IQR is what determines which numerical measures of center and spread are appropriate for describing a given distribution of a quantitative variable. The min, Q1, M, Q3, max are the measures I will use in this case. No, IQR does not determine which measure to use. the overall pattern of the quantitative variable is described by its shape, pattern and spread. A description of the distribution of a quantitative variable must include a graphical display, which is the histogram,and also a more precise numerical description of the center and spread of the distribution. The two main numerical measures are the mean and the median. This is all true, but does not answer the question. The two main numerical measures for the center of a distribution are the mean and the median. the three main measures of spread are range, inter-quartile range, and standard deviation. This is all true, but does not answer the question. When examining the distribution of a quantitative variable, one should describe the overall pattern of the data (shape, center, spread), and any deviations from the pattern (outliers).