DOCSLIB.ORG

Biomaterials

Total Page：16

File Type：pdf, Size：1020Kb

Download full-text PDF Read full-text
Biomaterials BIOMATERIALS Research in the Department of Biomaterials The Department of Biomaterials focuses on interdisci- New Methods for Analysis of Biomaterials plinary research in the field of biological and bio- Studying hierarchical biomaterials requires state-of-the-art mimetic materials. The emphasis is on under- experimental equipment, but there is also some need for the standing how the mechanical or other physical development of new approaches. Scanning methods based properties are governed by structure and compo- on the diffraction of synchrotron radiation, as well as the sition (see Fig. 1). Furthermore, research on nat- technique of small-angle x-ray scattering (SAXS) are continu- ural materials (such as bone or wood) has poten- ously developed to improve the characterization of hierarchi- tial applications in many fields. First, design con- cal biomaterials. Further technical improvement is expected cepts for new materials may be improved by from a dedicated scanning set-up which is currently being learning from Nature. Second, the understanding installed at the synchrotron BESSY in Berlin. of basic mechanisms by which the structure of bone or connective tissue is optimised opens the way for Plant Biomechanics Biotemplating studying diseases and, thus, for contributing to diagnosis (Ingo Burgert) (Oskar Paris) and development of treatment strategies. A third option is to use structures grown by Nature and transform them by phys- Mechanobiology Biomimetic Materials ical or chemical treatment into technically relevant materials (Richard Weinkamer) (Peter Fratzl) (biotemplating). Given the complexity of natural materials, new approaches for structural characterisation are needed. Mineralized Tissues Bone Research Some of these are further developed in the Department, in (Himadri S. Gupta) (Peter Fratzl) particular for studying hierarchical structures. Scanning Diffraction Beamline Hierarchical Structure of Natural Materials (Oskar Paris) The development of metals and alloys with increasing strength has been a constant trigger for the technical development of Fig. 2: Research groups in the Department of Biomaterials with our societies. Interestingly, Nature does not use metals as respective group leaders structural materials at all. Practically all biological materials are based on polymers and polymer-mineral composites. The Research Strategy required mechanical performance is obtained by an intelligent The research on biomaterials is currently concentrated in structure which is hierarchical and optimised at all levels. seven research groups as sketched in Fig. 2. Three groups (left column in Fig. 2) deal with “understanding” (see Fig. 1) Hierarchical Biological Understand the mechanical properties of biological materials and their Structure Materials (experiment and adaptation to external stimulus. Three more groups (right col- macro – micro – nano modelling) umn in Fig. 2) concentrate on more applied goals, relating to Mineralized Tissue the development of new materials, on the one hand, and to (bone, dentin, enamel, …) medical problems in bone research, on the other. Finally, a (Mechanical) Copy Plant Bodies Behaviour (biotemplating) seventh group is dedicated to the development of a new (wood, …) micro-focus beamline for scanning x-ray scattering applica- Connective Tissue tions at the BESSY synchrotron in Berlin. More detailed goals Functional (collagen, cartilage, …) Mimic of the different research groups are outlined below. Adaptation … (biomimetic materials) Plant Biomechanics Fig. 1: General research goals in the Department of Biomaterials The main goals are: · To understand plant tissue as a fibre composite in relation Mechanical Adaptation of Biomaterials to its mechanical adaptation; It is also well-known that biological materials constantly adapt · To understand the nano-structure and mechanical properties to changing mechanical needs. This is achieved by a strain- of the plant cell wall; sensing mechanism, which in most biological systems is not · To obtain basic knowledge on structure-property relation- fully elucidated. In the case of bone, for instance, spe- ships in plants for transfer to technical systems. cialized cells are thought to act as strain sensors and to be at the centre of a feed-back loop, called Mineralized Tissues bone remodelling cycle, where damaged The main goals are: bone is removed and replaced by new · To understand how bone and related calcified tissues are material. This process is crucial designed at the micro- and nano- levels to fulfil their for the tissue's capability of load-bearing and structural requirements; mechanical adaptation · To develop a theoretical formulation that relates the and self-repair. mechanical properties of mineralized tissues to their struc- ture at the sub-micron level. 26 Mechanobiology The main goals are: · To understand and predict the adaptation of materials to mechanical requirements by means of numerical simulation; · To improve the understanding of the biological response of natural tissues to mechanical stimulus and the associated feedback mechanisms by means of theoretical analysis. (a) (b) (c) (d) Biotemplating The main goals are: · To take natural tissues as scaffolds or moulds for the creation of novel engineering materials with improved mechanical and functional properties; Gustav Klimt (1862-1918): (a) normal, (b) bisphosphonate, (c) parathyroid hormone, (d) NaF · To preserve and/or replicate the hierarchical structure of Three ages of a women, 1905 the biological tissues down to the nanometer regime during the conversion process. Fig. 3: Various treatment strategies of osteoporosis investigated with back-scattered electron microscopy in collaboration with the Ludwig- Biomimetic Materials Boltzmann Institute of Osteology in Vienna, Austria (courtesy, The main goals are: Dr. Paul Roschger) · To use the building principles of natural hierarchical com- posites, such as bone, collagen or the plant cell wall, to improve existing materials by shaping and structuring. Peter Fratzl · Current work includes: Biomimetic polymer-mineral Director of the Department composites; Designed porous scaffolds with optimised of Biomaterials mechanical properties; Novel precious metal-based bio- nano-catalysts; synthesis of hydroxyapatite naoparticles with special shapes. Bone and Mineral Research This group works in close collaboration with external medical research groups and its main goals are: · To study clinical problems related to bone material quality in various bone diseases, such as osteoporosis or brittle bone disease, · To establish the effect of genotype on bone material in ani- mal models and for genetic diseases, · To develop new physical methodology for assessing bone material quality. Scanning Diffraction Beamline The main goals are: · To develop a microfocus synchrotron beamline for scanning x-ray scattering applications, in col- laboration with BESSY and the Federal Institute for Materials Research (BAM), the idea being to use the small-angle and/or diffraction signal to image a specimen with micrometer resolution; · To develop high-throughput tech- nology for online data analysis, to deal with the enormous amount of data collected in scanning diffraction applications; · To implement a platform for the study of biological specimens (in particular cryo-sections). 27 BIOLOGICAL MATERIALS Calcified Tissue Structure and Mechanics Structural Adaptation and Mechanisms Fibrillar Level Deformation Mechanisms in of Deformation in Calcified Tissues Mineralized Tendons and Bone The general aim of this group is to elucidate For partially mineralized avian tendons for low (< 1–2%) how the various structural features of natu- macroscopic strains, the fibril level deformation follows the ral calcified tissues (bone, tendon, cartilage) applied external stress, for larger strains, an unexpected relate to their mechanical behavior [1]. biphasic behavior is observed, where a portion of the fibrils Specifically, three types of tissues were relax back to their unstressed state while the remainder elon- addressed. (a) Mineralized cartilage, which is the gate to much larger strains, while maintaining macroscopic crucial interface between subchondral bone and cohesion (Fig. 2b). By combining the results with fractograph- Himadri Shikhar Gupta 26.06.1973 articular cartilage in articulating joints; (b) Parallel fibered ic analysis using scanning electron microscopy, we find that 1991-1996: M.Sc. in Physics mineralized collagen from tendon and bone, in order to eluci- the mineralized tendon consists, at the micrometer level, of a (Indian Institute of Technology, date mechanical deformation mechanisms at the fibril level; heterogeneously mineralized group of unmineralized and Kanpur, India) (c) And single osteons, the basic building block of compact fully mineralized fiber bundles of 2 – 4 micron diameter. Our 1996-2000: PhD, Physics (Department bone, comprising layers of lamellar bone around a blood ves- results are interpreted in terms of two-fiber composite model of Physics and Astronomy, Rutgers, The sel. The aim was to resolve their intra-lamellar structure in (Fig. 2b), inset) in which the highly mineralized fibers account State University of New Jersey, New terms of the orientation, size, shape and crystallographic for the macroscopic stiffness and the lowly mineralized fibers Brunswick, New Jersey, USA) structure of the nanometer size crystallites in relation to the the high work to fracture [2]. In contrast, our more recent Thesis: Phase Segregation and Alloying
Load more

Recommended publications
  • FEL Physics Summary
    VUV and X-Ray Free Electron Lasers: The Technology and Its Scientific Promise William Barletta and Carlo Rizzuto Sections I & III – Motivations & FEL Physics List of symbols fine structure constant dimensionless vector potential aw horizontal Twiss x bunching parameter b mean resolution error of BPMs BPMres position error of BPMs BPMpos remanent field BR undulator magnetic field strength Bw horizontal Twiss x speed of light c mean phase error in undulator penetration depth δp horizontal dispersion Dx derivative of Dx D´x FEL beam diameter on optic Dw energy chirp from CSR E/E beam emittance electron charge e beam energy E peak electric field in gun Eo normalized emittance n energy in the FEL pulse EPulse longitudinal space charge force Fsc angle of incidence j i 1 2 relativistic factor (E/ me c ) optical function in transport H magnetic coercivity HC Alfven current at =1 IAo beam current Ib BBU threshold current IBBU undulator parameter K mean undulator strength Krms undulator spatial frequency kw gain length LG th m harmonic wavelength m plasma wavelength P radiation wavelength r undulator wavelength w root of gain equation harmonic number m electron mass me number of electrons Ne electron density ne number of undulator periods Nu radiation power P input laser power Plaser noise power Pn pole roll angle error BNP (or Pierce) parameter quantum FEL parameter ´ atom density A quality factor Q dipole quality factor Qdipole FEL energy constraint ratio r1 FEL emittance constraint ratio r2 FEL diffraction constraint ratio r3 classical radius of electron re bend angle in undulator bend angle in achromat 2 th phase of i electron i kick relative to each pole error j mean energy spread of electrons e bunch length z relativistic plasma frequency p distance along undulator z mean longitudinal velocity <vz> impedance of free space Zo Rayleigh range ZR 3 I.
    [Show full text]
  • Bilateral NIST-PTB Comparison of Spectral Responsivity in the VUV
    Bilateral NIST-PTB Comparison of Spectral Responsivity in the VUV A Gottwald 1, M Richter 1, P-S Shaw 2, Z Li 2 and U Arp 2 1Physikalisch-Technische Bundesanstalt, Abbestraße 2-12, 10587 Berlin, Germany 2National Institute for Standards and Technology, 100 Bureau Dr., Gaithersburg, MD 20899-8410, U.S.A. E-mail: [email protected] Abstract. To compare the calibration capabilities for the spectral responsivity in the vacuum-ultraviolet spectral region between 135 nm and 250 nm, PTB and NIST agreed on a bilateral comparison. Calibrations of semiconductor photodiodes as transfer detectors were performed using monochromatized synchrotron radiation and cryogenic electrical substitution radiometers as primary detector standards. Great importance was attached to the selection of suitable transfer detector standards due to their critical issues in that wavelength regime. The uncertainty budgets were evaluated in detail. The comparison showed a reasonable agreement between the participants. However, it got obvious that the uncertainty level for this comparison cannot easily be further reduced due to the lack of sufficiently radiation-hard and long-term stable transfer standard detectors. Keywords: PACS: 07.60.Dq, 07.85.Qe, 85.60.Dw, 06.20.fb Bilateral NIST-PTB Comparison of Spectral Responsivity in the VUV 2 1. Introduction The last decade has seen numerous key comparisons in the field of photometry and radiometry between different national metrology institutes (NMIs) in the context of the Mutual Recognition Arrangement. At first, these comparisons were restricted to wavelengths longer than 200 nm, with just the exception of a recent pilot comparison from 10 nm to 20 nm [1].
    [Show full text]
  • Collimation System for the Bessy Fel∗
    T. Kamps / Proceedings of the 2004 FEL Conference, 381-384 381 COLLIMATION SYSTEM FOR THE BESSY FEL∗ T. Kamps Berliner Elektronenspeicherring-Gesellschaft fur¨ Synchrotronstrahlung BESSY, D-12489 Berlin, Germany Abstract magnet undulators. Each undulator is composed of mod- ules with length ranging from 1.6 m to 3.9 m, the total Beam collimation is an essential element for the success- length of the high energy FEL line is 70 m. A FODO lat- ful running of a linear accelerator based free electron laser. tice is superimposed onto the undulator structure with the The task of the collimation system is to protect the undu- quadrupole magnets located at the intersections between lator modules against mis-steered beam and dark-current. the undulator modules. For the present analysis in total 14 This is achieved by a set of apertures limiting the succeed- undulator modules are taken into account for the simulation ing transverse phase space volume and magnetic dogleg studies. The gap between the undulator poles is 10 mm, the structure for the longitudinal phase space. In the follow- beampipe radius is 4 mm. The undulator magnets are made ing the design of the BESSY FEL collimation system is of NdFeB in order to obtain large undulator K parameters. described together with detailed simulation studies. This material is very sensitive to irradiation, especially to the reduced dose deposited by high-energy electrons (> MOTIVATION 20 MeV). From studies with NdFeB under electron irra- Experiences from linac driven FEL operation (for exam- diation [4] the limit for acceptable beam loss in the undula- ple at TTF1 [1]) indicate that beam collimation is essential tor chamber has been derived.
    [Show full text]
  • The Diamond Light Source
    The Diamond Light Source ... a bright future for UK and World science Richard P. Walker, Technical Director What is Diamond ? • The largest scientific investment in the UK for 30 years • A synchrotron light source producing pinpoint UV and X-ray light beams of exceptional brightness • A ‘super microscope’ for new research opportunities into the structure and properties of matter What is Diamond ? • A Power Converter ! 15 MW of electrical power from the grid … 300-500 kW of X-rays … … but most of which only produces unwanted heat; only a fraction is selected for use in experiments. What is Synchrotron Radiation ? SR is electromagnetic radiation emitted when a high energy beam of charged particles (electrons) is deflected by a magnetic field. What’s so special about Synchrotron Radiation ? SR SR is emitted over a wide range of the electromagnetic spectrum, from Infra-red to hard X-rays Any desired radiation wavelength can be produced - enabling a very wide range of scientific and technological applications What’s so special about Synchrotron Radiation ? SR is very intense, and has extremely high brightness (emitted from a small area, with small angular divergence, determined by the properties of the electron beam) High brightness means: - it can be focused to sub-micron spot sizes: possibility of examining extremely small samples or investigating the structure and properties of objects with very fine spatial resolution - experiments can be carried out much more quickly: high through-put of samples or ability to follow chemical and biological reactions in real-time Diamond is a “third-generation” synchrotron radiation source • 1st generation: machines originally built for other purposes e.g.
    [Show full text]
  • The Tesla Free Electron Laser J
    THE TESLA FREE ELECTRON LASER J. Rossbach, for the TESLA FEL collaboration DESY, Notkestrasse 85, D22603 Hamburg, Germany Abstract occupied many scientists, a practical solution to this prob- lem has not yet been realized. To be an efficient research The TESLA Free Electron Laser (FEL) makes use of the tool, such a source would have to provide stable intensities high electron beam quality that can be provided by the su- with short pulses and repetition frequencies similar to what perconducting TESLA linac to drive a single pass FEL at is found in optical lasers. Exactly this seems to be possible wavelengths far below the visible. To reach a wavelength by using the so-called self amplified spontaneous emission of 6 nanometers, the TESLA Test Facility (TTF) currently process SASE. under construction at DESY will be extended to 1 GeV The basic principle [1] makes use of the fact that an elec- beam energy. Because there are no mirrors and seed-lasers tron beam of sufficient quality, passing a long undulator in this wavelength regime, the principle of Self-Amplified- magnet, exponentially amplifies an initially existing radi- Spontaneous-Emission (SASE) will be employed. A first ation field, if the photon wavelength λph matches a reso- test of both the principle and technical components is fore- nance condition determined by undulator parameters and seen at a photon wavelength larger than 42 nanometers. the beam energy: With respect to linac technology, the key prerequisite for such single-pass, high-gain FELs is a high intensity, λu 2 λph = (1 + K ) (1) diffraction limited, electron beam to be generated and ac- 2γ2 celerated without degradation.
    [Show full text]
  • 10 Bessy Ventilation Concept
    XFEL Tunnel Ventilation and Air Conditioning BESSY ventilation concept www.helmholtz-berlin.de BESSY I - History • 1979 BESSY GmbH was founded • 1982 BESSY operated until 1999 the electron storage ring facility BESSY I in Berlin-Wilmersdorf • 1999 BESSY I was cut back and 30 Beamlines were reconstructed at BESSY II www.helmholtz-berlin.de BESSY II - History • March 1993 the project team BESSY II starts work in Adlershof • 4. July 1994 Groundbreaking ceremony on the construction site for BESSY II • 13. Dec. 1995 Topping-out ceremony for the new building • 07. April 1997 Commencement of operation of the synchrotron www.helmholtz-berlin.de BESSY II - Commisioning • 23. June 1997 First acceleration of an electron beam in the synchrotron up to 1.9 GeV • 22. April 1998 First storage of an elctron beam in the storage ring and detection of synchrotron radiation • 16. July 1998 First production of „undulator“ –light • 4. Sept. 1998 Inauguration ceremony for the high brilliance synchrotron radiation source BESSY II www.helmholtz-berlin.de BESSY II - Operation • Oct. 1998 First scientific experiment • Jan. 1999 Official start of user-dedicated operation • Jan. 2000 Admission to the Leibnitz- Association • Dec. 2001 Inauguration of the BESSY extension office www.helmholtz-berlin.de BESSY II – Helmholtz-Zentrum Berlin • Jan. 2009 the Helmholtz-Zentrum Berlin (HZB) was foundet by merging the former Hahn- Meitner Institut (HMI) and BESSY • the Helmholtz-Zentrum Berlin now operates two scientific large scale facilities for investigating the structure
    [Show full text]
  • Lasers, Free-Electron
    1 Lasers, Free-Electron Claudio Pellegrini and Sven Reiche • Q1 University of California, Los Angeles, CA 90095-1547, USA e-mail: [email protected]; [email protected] Abstract Free-electron lasers are radiation sources, based on the coherent emission of synchrotron radiation of relativistic electrons within an undulator or wiggler. The resonant radiation wavelength depends on the electron beam energy and can be tuned over the entire spectrum from micrometer to X-ray radiation. The emission level of free-electron lasers is several orders of magnitude larger than the emission level of spontaneous synchrotron radiation, because the interaction between the electron beam and the radiation field modulates the beam current with the periodicity of the resonant radiation wavelength. The high brightness and the spectral range of this kind of radiation source allows studying physical and chemical processes on a femtosecond scale with angstrom resolution. Keywords free-electron laser; undulator; microbunching; SASE FEL; FEL oscillator; FEL amplifier; FEL parameter; gain length. 1 Introduction 2 2 Physical and Technical Principles 5 2.1 Undulator Spontaneous Radiation 6 2.2 The FEL Amplification 7 2.3 The Small-signal Gain Regime 10 2.4 High-gain Regime and Electron Beam Requirement 11 2.5 Three-dimensional Effects 13 OE038 2 Lasers, Free-Electron 2.6 Longitudinal Effects, Starting from Noise 14 2.7 Storage Ring–based FEL Oscillators 16 3 Present Status 17 3.1 Single-pass Free-electron Lasers 17 3.2 Free-electron Laser Oscillators 18 4 Future Development 20 Glossary 21 References 23 Further Reading 24 1 accelerator and can be used to accelerate Introduction the electron beam to higher energies.
    [Show full text]
  • Coherent X-Rays: Overview by Malcolm Howells
    Coherent x-rays: overview by Malcolm Howells Lecture 1 of the series COHERENT X-RAYS AND THEIR APPLICATIONS A series of tutorial–level lectures edited by Malcolm Howells* *ESRF Experiments Division ESRF Lecture Series on Coherent X-rays and their Applications, Lecture 1, Malcolm Howells CONTENTS Introduction to the series Books History The idea of coherence - temporal, spatial Young's slit experiment Coherent experiment design Coherent optics The diffraction integral Linear systems - convolution Wave propagation and passage through a transparency Optical propagators - examples Future lectures: 1. Today 2. Quantitative coherence and application to x-ray beam lines (MRH) 3. Optical components for coherent x-ray beams (A. Snigirev) 4. Coherence and x-ray microscopes (MRH) 5. Phase contrast and imaging in 2D and 3D (P. Cloetens) 6. Scanning transmission x-ray microscopy: principles and applications (J. Susini) 7. Coherent x-ray diffraction imaging: history, principles, techniques and limitations (MRH) 8. X-ray photon correlation spectroscopy (A. Madsen) 9. Coherent x-ray diffraction imaging and other coherence techniques: current achievements, future projections (MRH) ESRF Lecture Series on Coherent X-rays and their Applications, Lecture 1, Malcolm Howells COHERENT X-RAYS AND THEIR APPLICATIONS A series of tutorial–level lectures edited by Malcolm Howells* Mondays 5.00 pm in the Auditorium except where otherwise stated 1. Coherent x-rays: overview (Malcolm Howells) (April 7) (5.30 pm) 2. Coherence theory: application to x-ray beam lines (Malcolm Howells) (April 21) 3. Optical components for coherent x-ray beams (Anatoli Snigirev) (April 28) 4. Coherence and x-ray microscopes (Malcolm Howells) (May 26) (CTRL room ) 5.
    [Show full text]
  • Photons at DESY: a Coherent and Bright Perspective
    Photons at DESY: A coherent and bright perspective Jochen R. Schneider X-rays X-rays have a wavelength of the same order of magnitude as the distance of atoms in matter X-rays interact with the electrons X-rays penetrate matter X-rays are used to study the electronic and geometrical structure of matter X-rays are applied in basic research and engineering science as well as in medicine Wilhelm Conrad Röntgen Röntgen-Strukturbestimmung Laue-Beugung Bestimmung der Atomlagen aus den Röntgenstrahlen Intensitäten der Bragg-Reflexe Kristall Filmplatte Laue Beugungsdiagramme Erste Laue-Aufnahmen von Laue-Aufnahme an W. Friedrich, P. Knipping und M. von Laue Kohlen-Monoxyd-Myoglobin in 150 psec an Mineral-Einkristallen im Frühjahr 1912 (M. Wulff et al., ESRF-Grenoble) wiggler / undulators So far, the pace of progress in X-ray sciences has been closely tied to the strongly collimated development of polarised synchrotron radiation sources, where 3 orders of pulsed magnitude in brilliance Spektrum einer time were gained every 10 Wolfram Röntgen-Röhre high intensity years since 1960. wide spectral range European Synchrotron Radiation Facility European flagship for hard X-ray sciences Development of the brilliance of X-ray sources X-ray Laser Since the discovery of X-rays in 1895 the brilliance increased by more than 3 orders of magnitude every 10 years New generations of X-ray sources Open new opportunities for sciences without making the established work on older facilities less valuable As a result: steady increase of synchrotron radiation users Diffraction under extreme pressure The smaller the sample the larger is the achievable pressure Inelastic scattering under high pressure Speed of sound of Fe under pressure (ESRF: 2 ph/min) P=28GPa diamond X ray gasket sample 1 mm G.
    [Show full text]
  • The Scanning Transmission X-Ray Microscope at BESSY II
    The Scanning Transmission X-Ray Microscope at BESSY II Dissertation zur Erlangung des Doktorgrades der Mathematisch-Naturwissenschaftlichen Fakult¨aten der Georg-August-Universit¨at zu G¨ottingen vorgelegt von Urs Wiesemann aus G¨ottingen G¨ottingen 2003 D7 Referent: Prof. Dr. G. Schmahl Korreferent: Prof. Dr. R. Kirchheim Tag der m¨undlichen Pr¨ufung:09. 12. 2003 iii Contents Introduction 1 1 X-Ray Microscopy 3 1.1 Interaction of Soft X-rays With Matter ............... 3 1.1.1 X-ray Spectroscopy for Elemental and Chemical Mapping . 5 1.2 Transmission Zone Plates as High Resolution X-Ray Optics .... 6 1.3 Transmission X-Ray Microscopes (TXMs) and Scanning Transmis- sion X-Ray Microscopes (STXMs) .................. 8 1.4 Image Formation in the STXM ................... 10 1.4.1 Imaging With a Configured Detector ............ 14 1.4.2 Contrast and Positioning Noise ............... 16 1.4.3 Signal-to-Noise Ratio and Photon Numbers ........ 17 2 The STXM at the Undulator U41 at BESSY II 21 3 The STXM Monochromator 25 3.1 The Undulator U41 .......................... 25 3.2 Principle of Operation of the Monochromator ........... 31 3.2.1 The Diffraction Grating ................... 32 3.2.2 Spatial Coherence of the Zone Plate Illumination ..... 35 3.2.3 Spectral Contamination by Higher Undulator Harmonics . 35 3.3 The STXM Beamline ......................... 36 3.3.1 The Beam Monitor ...................... 38 3.4 Mechanical Setup of the Monochromator .............. 38 3.4.1 The Principle of the Mirror Motion ............. 40 3.4.2 The Alignment of the Monochromator ........... 43 3.5 Characterization of the Monochromator ............... 44 3.5.1 Photon Rate .........................
    [Show full text]
  • NSF Light Source Report
    National Science Foundation Light Source Panel Report September 15, 2008 NSF Advisory Panel on Light Source Facilities Contents Page Background iii Charge to the Panel vi Reporting Mechanism vii Resource Materials vii Members of the MPS Panel on Light Source Facilities viii Light Source Panel Report Executive Summary 1 Process 3 The Science Case 3 Education and Training 9 Partnering and NSF Stewardship 12 Findings and Conclusions 17 Appendices Appendix 1 – Science Case: History and Context 21 Appendix 2 – Science Case: The New Frontiers 26 Appendix 3 – Advisory Panel Members 31 Appendix 4 – Meetings, Fact Finding Workshops and Site Visits 34 Appendix 5 – Agenda, August 23, 2007 Panel Meeting 35 Appendix 6 – Agenda, January 9-10, 2008 Panel Meeting 36 Appendix 7 – Agenda, LBNL Site Visit 40 Appendix 8 – Agenda, SLAC Site Visit 42 Appendix 9 – Agenda, CHESS Site Visit 47 Appendix 10 – Agenda, SRC Site Visit 49 Appendix 11 – Table of Acronyms 50 ii BACKGROUND (Supplied by NSF) There are currently six federally-supported light source facilities in the US, as follows (dates show year of commissioning)1: • Stanford Synchrotron Radiation Laboratory (SSRL) at the Stanford Linear Accelerator Center (1974) • Cornell High Energy Synchrotron Source (CHESS) at Cornell University (1980) • National Synchrotron Light Source (NSLS) at Brookhaven National Laboratory (1982) • Synchrotron Radiation Center (SRC) at the University of Wisconsin (1985) • Advanced Light Source (ALS) at Lawrence Berkeley National Laboratory (1993) • Advanced Photon Source (APS) at Argonne National Laboratory (1996) The Department of Energy (DOE) Office of Basic Energy Sciences supports the four facilities located at national laboratories; NSF (through the Division of Materials Research) is the steward for the two facilities located at universities.
    [Show full text]
  • Two Orbit Operation at Bessy Ii - During a User Test Week∗
    10th Int. Particle Accelerator Conf. IPAC2019, Melbourne, Australia JACoW Publishing ISBN: 978-3-95450-208-0 doi:10.18429/JACoW-IPAC2019-THYYPLM2 TWO ORBIT OPERATION AT BESSY II - DURING A USER TEST WEEK∗ P. Goslawskiy, F. Andreas1, F. Armborst1, T. Atkinson, J. Feikes, A. Jankowiak1, J. Li, T. Mertens, M. Ries, A.Schälicke, G. Schiwietz, G. Wüstefeld, Helmholtz-Zentrum Berlin, Berlin, Germany 1also at Humboldt-Universität zu Berlin, Berlin, Germany Abstract For the upcoming MBA light sources, so far, only very long Operating a storage ring close to a horizontal resonance bunches of a few hundred pico-seconds length in a homoge- and manipulating the transverse non-linear beam dynamics neous multi bunch (MB) filling are foreseen to avoid reduced can generate stable Transverse Resonance Island Buckets lifetime, intra-beam scattering and collective instabilities. (TRIBs), which give a 2nd stable orbit in the ring. Both orbits This will make time-resolved experiments more difficult at can be populated with different electron bunch filling pat- these facilities, which has already triggered an ongoing dis- terns and provide two different radiation sources to the user cussion and the request for timing modes with different pulse community. Such a machine setting has been established repetition rates [6]. at BESSY II and was tested under realistic user conditions The pulse repetition rate can be easily changed in a stor- in a first ‘TRIBs/Two Orbit User Test Week’ in February age ring based light source by changing the stored filling 2018. Results and user feedback will be discussed in this pattern. The lowest repetition rate is achieved when only contribution.
    [Show full text]