DO YOU HAVE VARICOSE OR EXPERIENCE LEG PAIN AND FATIGUE? You may have superficial venous reflux disease.

LEG ANATOMY VNUS CLOSURE™ PROCEDURE

Perforating veins connect the deep The VNUS Closure procedure is a minimally invasive Saphenofemoral system with the superficial system Junction treatment alternative to traditional vein stripping. Skin The tiny catheter powered by radiofrequency (RF) Perforating Femoral Vein Vein (Deep System) energy delivers heat to the vein wall. As the thermal energy is delivered, the vein wall shrinks and the Superficial Deep Vein Vein vein is sealed closed. Once the diseased vein is Femoral Vein (Deep System) closed, blood is re-routed to other healthy veins.

Disposable catheter Controlled heat Catheter withdrawn, Small Saphenous Vein inserted into vein collapses vein closing vein (Superficial System) (Superficial System)

VEIN VALVE FAILURE

Superficial venous reflux Healthy Vein Valve Diseased Vein Valve develops when the vein valves that keep blood flowing out of PROCEDURAL HIGHLIGHTS your legs and back to your heart become damaged or diseased. • Relief of symptoms This can cause blood to pool in • Outpatient procedure your legs and result in dilated • Local or general or . Healthy valves keep blood Diseased valves cause blood • Most patients resume normal activities within moving in one direction to move in both directions, elevating venous pressure 1-2 days • Good cosmetic outcome with minimal or no SYMPTOMS: SUPERFICIAL VENOUS REFLUX scarring, bruising or swelling

COMMON SIGNS AND SYMPTOMS OF SUPERFICIAL VENOUS REFLUX INCLUDE: • Varicose veins • Heaviness and fatigue • Restless Legs e VNUS Closure procedure • Leg or ankle swelling • Pain, aching, or cramping • Skin changes • Ulcers • Burning or itching of the skin is covered by most insurance providers for patients diagnosed SUPERFICIAL VENOUS REFLUX IS PROGRESSIVE AND IF LEFT UNTREATED, MAY with venous reux WORSEN OVER TIME. BELOW ARE THE MANIFESTATIONS OF THE DISEASE:1

Swelling and Skin Skin Color and Varicose Veins Venous Ulcers Texture Changes INDICATIONS: The VNUS Closure procedures treat leg veins in the superficial Discoloration and perforating systems that have venous reflux, the underlying cause of varicose veins and venous ulcers. Individual results may vary based on each patient’s condition. CONTRAINDICATIONS: Patients with thrombus (blood clots) in the vein segment to be treated should not have the VNUS Closure Procedures. POTENTIAL COMPLICATIONS: As with all medical procedures, potential risk and complications exist including vessel perforation (when the catheter punctures the vein wall), thrombosis, (when a blood clot travels to the lungs), phlebitis (inflammation of the vein), , nerve damage, arteriovenous fistula (an abnormal connection between an Your physician can determine if superficial venous reflux is present through an ultrasound examination. artery and a vein), hematoma (bruising), and skin burn. Consult with a physician 1 Photos courtesy of Rajabrata Sarkar, MD, PhD. to receive more information.

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