These search results have not been confirmed by NIEHS and are therefore, not official. They are to be used only for general information and to inform the public and grantees on the breadth of research funded by NIEHS. Viewing 641 publications Export to Excel (http://www.niehs.nih.gov//portfolio/index.cfm/portfolio/sciencecodepubs/sc/09/topic/9/format/excel) Publication Title Authors Grant Journal (Pub date) PubMed Pub Number(s) Link Year A unified alternative telomere-lengthening pathway in Kockler, Zachary W; R21ES030307 Mol Cell (2021 04 15) 33639094 2021 yeast survivor cells. Comeron, Josep M; Malkova, Anna Aldehyde dehydrogenase inhibitors promote DNA Grimley, Edward; Cole, R01ES030335 Theranostics (2021) 33664846 2021 damage in ovarian cancer and synergize with Alexander J; Luong, ATM/ATR in ... Thong T; McGonigal, Stacy C; Sinno, Sarah; Yang, Do ... Alkylating and oxidative stresses in smoking and Shih, Ying-Ming; R01ES030557 Free Radic Biol Med (2021 33418114 2021 non-smoking patients with COPD: Implications for lu Chang, Yuan-Jhe; 02 20) ... Cooke, Marcus S; Pan, Chih-Hong; Hu, Ching-Hsuan; Chao, Mu-R ... Biomarkers of nucleic acid oxidation - A summary Chao, Mu-Rong; Evans, R01ES030557 Redox Biol (2021 06) 33579665 2021 state-of-the-art. Mark D; Hu, Chiung-Wen; Ji, Yunhee; Møller, Peter; Rossner, Pavel; Cooke ... Chemoproteomic Approach toward Probing the Zhang, Quanqing; Dong, R35ES031707 Anal Chem (2021 07 13) 34185510 2021 Interactomes of Perfluoroalkyl Substances. Xuejiao; Lu, Jiuwei; Song, Jikui; Wang, Yinsheng Clocks, cancer, and chronochemotherapy. Sancar, Aziz; Van R01ES027255 Science (2021 01 01) 33384351 2021 Gelder, Russell N CometChip analysis of human primary lymphocytes Ngo, Le P; Kaushal, P30ES000002, Free Radic Biol Med (2021 34324980 2021 enables quantification of inter-individual differenc ... Simran; Chaim, Isaac A; P30ES002109, 10) Mazzucato, Patrizia; P42ES027707, Ricciardi, Catherine; U01ES029520 Samson, ... Comparative analyses of two primate species diverged Akkose, Umit; Kaya, R01ES027255 BMC Genomics (2021 34362292 2021 by more than 60 million years show different ra ... Veysel Ogulcan; Aug 06) Lindsey-Boltz, Laura; Karagoz, Zeynep; Brown, Adam D; Larse ... Compensation for the absence of the catalytically Stepchenkova, Elena I; R01ES015869 Genetics (2021 Jun 24) 33844024 2021 active half of DNA polymerase ε in yeast by positi ... Zhuk, Anna S; Cui, Jian; Tarakhovskaya, Elena R; Barbari, Stephanie R; S ... Comprehensive Analysis of DNA Adducts Using Walmsley, Scott J; Guo, R01ES019564, Anal Chem (2021 04 27) 33844920 2021 Data-Independent wSIM/MS2 Acquisition and Jingshu; Murugan, R03ES031188 wSIM-City. Paari; Weight, Christopher J; Wang, Jinhua; Villalta, ... Construction of a Three-Color Prism-Based TIRF Fairlamb, Max S; K99ES031148, Biology (Basel) (2021 Jun 34201434 2021 Microscope to Study the Interactions and Dynamics of Whitaker, Amy M; R01ES029203 23) ... Bain, Fletcher E; Spies, Maria; Freudenthal, Bret D CTCF binding modulates UV damage formation to Sivapragasam, Smitha; R01ES028698, EMBO J (2021 Sep 06) 34487363 2021 promote mutation hot spots in melanoma. Stark, Bastian; Albrecht, R01ES032814, Amanda V; Bohm, R21ES029655 Kaitlynne A; Mao, Peng; Emehise ... Cytotoxicity and genotoxicity of the carcinogen Bellamri, Medjda; R01ES030559 Arch Toxicol (2021 06) 33938965 2021 aristolochic acid I (AA-I) in human bladder RT4 cell ... Brandt, Kyle; Brown, Christina V; Wu, Ming-Tsang; Turesky, Robert J Distinct pathways of homologous recombination Prakash, Rohit; R01ES030335 Nat Commun (2021 07 12) 34253720 2021 controlled by the SWS1-SWSAP1-SPIDR complex. Sandoval, Thomas; Morati, Florian; Zagelbaum, Jennifer A; Lim, Pei-Xin; White, ... Distinct roles for RSC and SWI/SNF chromatin Bohm, Kaitlynne A; R01ES028698 Genome Res (2021 Jun) 34001524 2021 remodelers in genomic excision repair. Hodges, Amelia J; Czaja, Wioletta; Selvam, Kathiresan; Smerdon, Michael J; M ... DNA damage-how and why we age? Yousefzadeh, Matt; U01ES029603 Elife (2021 Jan 29) 33512317 2021 Henpita, Chathurika; Vyas, Rajesh; Soto-Palma, Carolina; Robbins, Paul; Nied ... DNA glycosylase deficiency leads to decreased Paluri, Sesha L; Burak, R35ES031708 DNA Repair (Amst) (2021 34186496 2021 severity of lupus in the Polb-Y265C mouse model. Matthew; Senejani, 09) Alireza G; Levinson, Madison; Rahim, Tania; Clairmon ... DNA ligase I fidelity mediates the mutagenic ligation Kamble, Pradnya; Hall, R00ES026191 J Biol Chem (2021 33600799 2021 of pol β oxidized and mismatch nucleotide inse ... Kalen; Chandak, Jan-Jun) Mahesh; Tang, Qun; Çağlayan, Melike DNA Polymerase and Mismatch Repair Exert Distinct Chung, Jiil; Maruvka, R01ES028271 Cancer Discov (2021 May) 33355208 2021 Microsatellite Instability Signatures in Normal an ... Yosef E; Sudhaman, Sumedha; Kelly, Jacalyn; Haradhvala, Nicholas J; Bianc ... DNA Polymerase II Supports the Replicative Bypass Wang, Yinan; Wu, Jun; R35ES031707 Chem Res Toxicol (2021 33417436 2021 of N2-Alkyl-2'-deoxyguanosine Lesions in Escherich Wu, Jiabin; Wang, 03 15) ... Yinsheng DNA Sequence Modulates the Efficiency of Tomar, Rachana; R01ES029357, Chem Res Toxicol (2021 33595290 2021 NEIL1-Catalyzed Excision of the Aflatoxin Minko, Irina G; Kellum R01ES031086 03 15) B1-Induced Formam ... Jr, Andrew H; Voehler, Markus W; Stone, Michael P; McCul ... DNA-protein crosslinks are repaired via homologous Chesner, Lisa N; R01ES023350 DNA Repair (Amst) (2021 33316746 2021 recombination in mammalian mitochondria. Essawy, Maram; 01) Warner, Cecilia; Campbell, Colin DNMT1 reads heterochromatic H4K20me3 to Ren, Wendan; Fan, R35ES031707 Nat Commun (2021 05 03) 33941775 2021 reinforce LINE-1 DNA methylation. Huitao; Grimm, Sara A; Kim, Jae Jin; Li, Linhui; Guo, Yiran; Petell, Christ ... Dynamic Processing of a Common Oxidative DNA Raper, Austin T; R01ES028271 J Mol Biol (2021 03 05) 33450252 2021 Lesion by the First Two Enzymes of the Base Excision Maxwell, Brian A; Suo, Re ... Zucai Eliminating hypoxic tumor cells improves response to Mehibel, Manal; Xu, R01ES016486 J Clin Invest (2021 06 01) 34060485 2021 PARP inhibitors in homologous recombination-def ... Yu; Li, Caiyun G; Moon, Eui Jung; Thakkar, Kaushik N; Diep, Anh N; Kim, R ... Elongation factor ELOF1 drives transcription-coupled Geijer, Marit E; Zhou, R01ES028698, Nat Cell Biol (2021 06) 34108662 2021 repair and prevents genome instability. Di; Selvam, Kathiresan; R21ES029655 Steurer, Barbara; Mukherjee, Chirantani; Evers, ... Ending a diagnostic odyssey: Moving from exome to Friedman, Jennifer; U01ES029603 Mol Genet Genomic Med 34076366 2021 genome to identify cockayne syndrome. Bird, Lynne M; Haas, (2021 Jul) Richard; Robbins, Shira L; Nahas, Shareef A; Dimmock, ... Environmentally induced ribosomal DNA (rDNA) Lou, Jianlin; Yu, P30ES000002, Environ Int (2021 08) 33774497 2021 instability in human cells and populations exposed to h Shoukai; Feng, R01ES027981 ... Lingfang; Guo, Xinnian; Wang, Meng; Branco, Alan T; Li, Tao; ... Enzymatic bypass and the structural basis of Ghodke, Pratibha P; R01ES010546, J Biol Chem (2021 33839151 2021 miscoding opposite the DNA adduct Mali, Jyotirling R; R01ES026955 Jan-Jun) 1,N2-ethenodeoxyguano ... Patra, Amritraj; Rizzo, Carmelo J; Guengerich, F Peter; ... Etheno adducts: from tRNA modifications to DNA Guengerich, F Peter; R01ES010546, Genes Environ (2021 Jun 34130743 2021 adducts and back to miscoding ribonucleotides. Ghodke, Pratibha P R01ES026955 16) EXO5-DNA structure and BLM interactions direct Hambarde, Shashank; R01ES029680 Mol Cell (2021 07 15) 34197737 2021 DNA resection critical for ATR-dependent replication Tsai, Chi-Lin; Pandita, ... Raj K; Bacolla, Albino; Maitra, Anirban; Charaka, ... Exploiting DNA Endonucleases to Advance Thompson, Marlo K; R01ES030084, Biology (Basel) (2021 Jun 34198612 2021 Mechanisms of DNA Repair. Sobol, Robert W; R01ES030084, 14) Prakash, Aishwarya R35ES031708 Fluorescence Sheds Light on DNA Damage, DNA Owiti, Norah A; Nagel, P30ES000002, Trends Cancer (2021 03) 33203608 2021 Repair, and Mutations. Zachary D; Engelward, P42ES027707, Bevin P U01ES029520, U44ES024698 Formation and repair of unavoidable, endogenous Housh, Kurt; Jha, Jay S; R01ES021007 DNA Repair (Amst) (2021 33385969 2021 interstrand cross-links in cellular DNA. Haldar, Tuhin; Amin, 02) Saosan Binth Md; Islam, Tanhaul; Wallace, Amanda ... Fused in sarcoma regulates DNA replication timing Jia, Weiyan; Kim, Sang R01ES025166 J Biol Chem (2021 Aug 34375640 2021 and kinetics. Hwa; Scalf, Mark A; 08) Tonzi, Peter; Millikin, Robert J; Guns, William M; ... Genes affecting ionizing radiation survival identified Gupta, Meenal; Liu, R01ES027121 Hum Mutat (2021 Sep) 34153142 2021 through combined exome sequencing and functio ... Xiangfei; Teraoka, Sharon N; Wright, Jocyndra A; Gatti, Richard A; Quinlan, ... Genome-wide circadian rhythm detection methods: Mei, Wenwen; Jiang, R01ES027255 Brief Bioinform (2021 32672832 2021 systematic evaluations and practical guidelines. Zhiwen; Chen, Yang; May 20) Chen, Li; Sancar, Aziz; Jiang, Yuchao Genome-wide mapping of genomic DNA damage: Amente, Stefano; Scala, R01ES030557 Cell Mol Life Sci (2021 34463773 2021 methods and implications. Giovanni; Majello, Aug 31) Barbara; Azmoun, Somaiyeh; Tempest, Helen G; Premi, ... GIGYF1 loss of function is associated with clonal Zhao, Yajie; Stankovic, DP2ES030554 Nat Commun (2021 07 07) 34234147 2021 mosaicism and adverse metabolic health. Stasa; Koprulu, Mine; Wheeler, Eleanor; Day, Felix R; Lango Allen, Han ... Hematopoietic mosaic chromosomal alterations Zekavat, Seyedeh M; DP2ES030554 Nat Med (2021 06) 34099924 2021 increase the risk for diverse types of infection. Lin, Shu-Hong; Bick, Alexander G; Liu, Aoxing; Paruchuri, Kaavya; Wang, Ch ... Impact of structural ageism on greater violence against Chang, E-Shien; Monin, R01ES005775 BMJ Open (2021 05 13) 33986041 2021 older persons: a cross-national study of 56 ... Joan K; Zelterman, Daniel; Levy, Becca R Insights into the mismatch discrimination mechanism Jung, Hunmin; Lee, R01ES026676 Biochem J (2021 May 14) 33881499 2021 of Y-family DNA polymerase Dpo4. Seongmin Insights into the substrate discrimination mechanisms Ouzon-Shubeita, Hala; R01ES026676 Biochem J (2021 May 28) 33960375 2021 of methyl-CpG-binding domain 4. Schmaltz, Lillian F; Lee, Seongmin Investigation of Break-Induced Replication in Yeast. Osia, Beth; Elango, R21ES030307 Methods Mol Biol (2021) 32840789 2021 Rajula; Kramara, Juraj; Roberts, Steven A; Malkova, Anna Is high resolution a strict requirement for mass Chang, Yuan-Jhe; R01ES030557 Chemosphere (2021 Jul) 33979922 2021 spectrometry-based cellular DNA adductomics? Cooke, Marcus S; Chen, Yet-Ran; Yang, Shun-Fa; Li, Pei-Shan; Hu, Chiung-Wen; ... Large mosaic copy number variations confer autism Sherman, Maxwell A; DP2ES030554 Nat Neurosci (2021 02) 33432194 2021 risk. Rodin, Rachel E; Genovese, Giulio; Dias, Caroline; Barton, Alison R; Mukame ... Large-scale preparation of fluorescence multiplex host Piett, C G; Pecen, T J; P30ES000002, Nat Protoc (2021 Sep) 34363069 2021 cell reactivation (FM-HCR) reporters. Laverty, D J; Nagel, Z U01ES029520 D Light-induced modulation of DNA recognition by the Tavakoli, Amirrasoul; R01ES025987 RSC Chem Biol (2021 Apr 34041491 2021 Rad4/XPC damage sensor protein. Paul, Debamita; Mu, 01) Hong; Kuchlyan, Jagannath; Baral, Saroj; Ansari, Anj ... Long-term survival of an ovarian cancer patient Sullivan, Meghan R; R01ES007061, Cold Spring Harb Mol 33832919 2021 harboring a RAD51C missense mutation. Prakash, Rohit; Rawal, R01ES030335 Case Stud (2021 04) Yashpal; Wang, Weibin; Sung, Patrick; Radke, Marc R ... m6A-RNA Demethylase FTO Inhibitors Impair Huff, Sarah; Tiwari, R35ES031707, ACS Chem Biol (2021 02 33412003 2021 Self-Renewal in Glioblastoma Stem Cells. Shashi Kant; Gonzalez, T32ES018827 19) Gwendolyn M; Wang, Yinsheng; Rana, Tariq M Mapping ribonucleotides embedded in genomic DNA Gombolay, Alli L; R01ES026243 Nat Protoc (2021 07) 34089018 2021 to single-nucleotide resolution using Ribose-Map. Storici, Francesca Mitochondrial Transcription Factor A Binds to and He, Xiaomei; Wang, R35ES031707 Anal Chem (2021 01 19) 33290046 2021 Promotes Mutagenic Transcriptional Bypass of O4-Al Pengcheng; Wang, ... Yinsheng Molecular mechanisms and cardiovascular Abdelgawad, Ibrahim U01ES029603 Pharmacol Ther (2021 05) 33275998 2021 implications of cancer therapy-induced senescence. Y; Sadak, Karim T; Lone, Diana W; Dabour, Mohamed S; Niedernhofer, Laura J; ... Monitoring genome-wide replication fork Kit Leng Lui, Sarah; R01ES025166 Nat Protoc (2021 02) 33442052 2021 directionality by Okazaki fragment sequencing in Keegan, Sarah; Tonzi, mammalian c ... Peter; Kahli, Malik; Chen, Yu-Hung; Chalhoub, Noor; ... NAD+ metabolism controls growth inhibition by HIF1 Luczak, Michal W; R01ES028072, Cell Cycle (2021 Aug 12) 34382917 2021 in normoxia and determines differential sensitivi ... Krawic, Casey; R01ES031002, Zhitkovich, Anatoly R01ES031979 Noninvasive Assessment of Epidermal Genomic Muradova, Elnara; Patel, R01ES030562 J Invest Dermatol (2021 32553564 2021 Markers of UV Exposure in Skin. Nishit; Sell, Brittney; 01) Bittencourt, Bruna B; Ojeda, Sandra S; Adelman ... PARP14 regulates cyclin D1 expression to promote O'Connor, Michael J; R01ES026184 Oncogene (2021 Jul) 34158578 2021 cell-cycle progression. Thakar, Tanay; Nicolae, Claudia M; Moldovan, George-Lucian PARP1: Structural insights and pharmacological Spiegel, Jacob O; Van R35ES031638 DNA Repair (Amst) (2021 33940558 2021 targets for inhibition. Houten, Bennett; 07) Durrant, Jacob D Phosphoinositide 3-Kinase (PI3K) Reactive Oxygen Mishra, Rosalin; Yuan, R15ES029675, Int J Mol Sci (2021 Feb 33669867 2021 Species (ROS)-Activated Prodrug in Combination with Long; Patel, Hima; R15ES029675 19) ... Karve, Aniruddha S; Zhu, Haizhou; White, Aaron; Alan ... Post-transcriptional diversity in riboproteins and Cruz, Jurandir; Lemos, R01ES027981 Semin Cancer Biol (2021 34474152 2021 RNAs in aging and cancer. Bernardo Aug 30) Protein-coding repeat polymorphisms strongly shape Mukamel, Ronen E; DP2ES030554 Science (2021 09 24) 34554798 2021 diverse human phenotypes. Handsaker, Robert E; Sherman, Maxwell A; Barton, Alison R; Zheng, Yiming; McC ... Publisher Correction: Elongation factor ELOF1 drives Geijer, Marit E; Zhou, R01ES028698, Nat Cell Biol (2021 Jul) 34163038 2021 transcription-coupled repair and prevents genom ... Di; Selvam, Kathiresan; R21ES029655 Steurer, Barbara; Mukherjee, Chirantani; Evers, ... RNA-binding proteins contribute to small RNA He, Baoye; Cai, Qiang; R01ES025121 Nat Plants (2021 03) 33633358 2021 loading in plant extracellular vesicles. Qiao, Lulu; Huang, Chien-Yu; Wang, Shumei; Miao, Weili; Ha, Tommy; Wan ... Single-molecule imaging reveals replication fork Lee, Wei Ting C; Yin, R01ES031658 Nat Commun (2021 05 05) 33953191 2021 coupled formation of G-quadruplex structures hinder Yandong; Morten, ... Michael J; Tonzi, Peter; Gwo, Pam Pam; Odermatt, Diana ... Structure of a Stable Interstrand DNA Cross-Link Kellum Jr, Andrew H; R01ES029357 Biochemistry (2021 01 12) 33382597 2021 Involving a β-N-Glycosyl Linkage Between an N6-dA Qiu, David Y; Voehler, A ... Markus W; Martin, William; Gates, Kent S; Stone, M ... Super hotspots and super coldspots in the repair of Jiang, Yuchao; Li, R00ES030015, J Biol Chem (2021 33771559 2021 UV-induced DNA damage in the human genome. Wentao; Lindsey-Boltz, R01ES027255 Jan-Jun) Laura A; Yang, Yuchen; Li, Yun; Sancar, Aziz The emerging determinants of replication fork Thakar, Tanay; R01ES026184 Nucleic Acids Res (2021 33978751 2021 stability. Moldovan, 07 21) George-Lucian The interplay of RNA:DNA hybrid structure and Kumar, Charanya; R01ES031635 Elife (2021 Sep 08) 34494544 2021 G-quadruplexes determines the outcome of Batra, Sahil; Griffith, R-loop-replis ... Jack D; Remus, Dirk The Rad51 paralog complex Rad55-Rad57 acts as a Roy, Upasana; Kwon, R01ES007061 Mol Cell (2021 03 04) 33421364 2021 molecular chaperone during homologous Youngho; Marie, Lea; recombination. Symington, Lorraine; Sung, Patrick; Lisby, Michael; G ... The Role of Senescent Cells in Acquired Drug Thompson, Elizabeth L; U01ES029603 Cancers (Basel) (2021 May 34066966 2021 Resistance and Secondary Cancer in BRAFi-Treated Hu, Jiayi J; 07) Melano ... Niedernhofer, Laura J The scaffold protein XRCC1 stabilizes the formation Tang, Qun; Çağlayan, R00ES026191 J Biol Chem (2021 Jul 30) 34339737 2021 of polβ/gap DNA and ligase IIIα/nick DNA complex Melike ... The SOS Error-Prone DNA Polymerase V Mutasome Sikand, Adhirath; R35ES028343 Cells (2021 05 01) 34062858 2021 and β-Sliding Clamp Acting in Concert on Undamaged Jaszczur, Malgorzata; DNA ... Bloom, Linda B; Woodgate, Roger; Cox, Michael M; Goodma ... Versatile cell-based assay for measuring DNA Li, Yong; Mao, Peng; R21ES028549 Sci Rep (2021 Sep 15) 34526526 2021 alkylation damage and its repair. Basenko, Evelina Y; Lewis, Zachary; Smerdon, Michael J; Czaja, Wioletta Whole-exome imputation within UK Biobank powers Barton, Alison R; DP2ES030554 Nat Genet (2021 08) 34226706 2021 rare coding variant association and fine-mapping ana Sherman, Maxwell A; ... Mukamel, Ronen E; Loh, Po-Ru YY1 interacts with guanine quadruplexes to regulate Li, Lin; Williams, R35ES031707, Nat Chem Biol (2021 02) 33199912 2021 DNA looping and gene expression. Preston; Ren, Wendan; T32ES018827 Wang, Michelle Y; Gao, Zi; Miao, Weili; Huang, Ming; ... A special issue dedicated to Dr. Bruce N. Ames: Walker, Graham C R35ES028303 Mutat Res Genet Toxicol 32087846 2020 Introduction. Environ Mutagen (2020 Jan) A stapled POL κ peptide targets REV1 to inhibit Chatterjee, Nimrat; P30ES002109, Environ Mol Mutagen 32573829 2020 mutagenic translesion synthesis. D'Souza, Sanjay; R35ES028303 (2020 10) Shabab, Mohammad; Harris, Cynthia A; Hilinski, Gerard J; V ... Activity profiling and crystal structures of Rut, Wioletta; Lv, R01ES025166 Sci Adv (2020 10) 33067239 2020 inhibitor-bound SARS-CoV-2 papain-like protease: A Zongyang; Zmudzinski, fram ... Mikolaj; Patchett, Stephanie; Nayak, Digant; Snipas, ... An introduction for the special issue on environmental Yan, Shan; Vaziri, R01ES029079 Environ Mol Mutagen 32683747 2020 health and genome integrity. Cyrus (2020 08) Analysis of Telomere Length and Aberrations by Fouquerel, Elise; R00ES027028 Methods Mol Biol (2020) 31989559 2020 Quantitative FISH. Opresko, Patricia AP-endonuclease 1 sculpts DNA through an anchoring Hoitsma, Nicole M; R01ES029203 Nucleic Acids Res (2020 32542366 2020 tyrosine residue on the DNA intercalating loop. Whitaker, Amy M; 07 27) Beckwitt, Emily C; Jang, Sunbok; Agarwal, Pratul K; Van Hou ... Arsenic Exposure and Compromised Protein Quality Tam, Lok Ming; Wang, R35ES031707 Chem Res Toxicol (2020 32410444 2020 Control. Yinsheng 07 20) Arsenite Binds to ZNF598 to Perturb Tam, Lok Ming; Jiang, R35ES031707 Chem Res Toxicol (2020 32324387 2020 Ribosome-Associated Protein Quality Control. Ji; Wang, Pengcheng; 07 20) Wang, Yinsheng Associations of smoking and air pollution with Kupsco, Allison; P30ES009089, Environ Int (2020 11) 32791345 2020 peripheral blood RNA N6-methyladenosine in the Gonzalez, Gwendolyn; R01ES025121, Beijin ... Baker, Brennan H; R01ES025225, Knox, Julia M; Zheng, R01ES027845, Yinan; Wang, She ... T32ES007322 Asymmetric repair of UV damage in nucleosomes Mao, Peng; Smerdon, R01ES028698 Genome Res (2020 01) 31871068 2020 imposes a DNA strand polarity on somatic mutations Michael J; Roberts, in ... Steven A; Wyrick, John J Atypical UV Photoproducts Induce Non-canonical Laughery, Marian F; R01ES028698, Cell Rep (2020 11 17) 33207206 2020 Mutation Classes Associated with Driver Mutations in Brown, Alexander J; R21ES029655 ... Bohm, Kaitlynne A; Sivapragasam, Smitha; Morris, Haley ... Cancer Risks Associated With Germline PALB2 Yang, Xin; Leslie, R01ES027121 J Clin Oncol (2020 03 01) 31841383 2020 Pathogenic Variants: An International Study of 524 Goska; Doroszuk, Famil ... Alicja; Schneider, Sandra; Allen, Jamie; Decker, Brennan; ... Cancers from Novel Pole-Mutant Mouse Models Galati, Melissa A; R01ES028271 Cancer Res (2020 12 15) 32938641 2020 Provide Insights into Polymerase-Mediated Hodel, Karl P; Gams, Hypermutagenes ... Miki S; Sudhaman, Sumedha; Bridge, Taylor; Zahurancik, ... Catalytic mechanism of the mismatch-specific DNA Ouzon-Shubeita, Hala; R01ES026676 Biochem J (2020 05 15) 32297632 2020 glycosylase methyl-CpG-binding domain 4. Jung, Hunmin; Lee, Michelle H; Koag, Myong-Chul; Lee, Seongmin Characterization of long G4-rich enhancer-associated Williams, Jonathan D; R01ES030084, Nucleic Acids Res (2020 32383760 2020 genomic regions engaging in a novel loop:loop ' ... Houserova, Dominika; R01ES030084 06 19) Johnson, Bradley R; Dyniewski, Brad; Berroyer, Alexa ... Chromatin remodeling and mismatch repair: Access Goellner, Eva M R00ES026653 DNA Repair (Amst) (2020 31698199 2020 and excision. 01) Chromosomal alterations among age-related Terao, Chikashi; DP2ES030554 Nature (2020 08) 32581364 2020 haematopoietic clones in Japan. Suzuki, Akari; Momozawa, Yukihide; Akiyama, Masato; Ishigaki, Kazuyoshi; Yamam ... Collision-Induced Dissociation Studies of Protonated Cui, Yuxiang; Yuan, R01ES029749 J Am Soc Mass Spectrom 32134268 2020 Ions of Alkylated Thymidine and 2'-Deoxyguanosi ... Jun; Wang, Pengcheng; (2020 Apr 01) Wu, Jun; Yu, Yang; Wang, Yinsheng Comparison of the Base Excision and Direct Reversal Caffrey, Paul J; Kher, R01ES028865, Chem Res Toxicol (2020 32293880 2020 Repair Pathways for Correcting 1,N6-Ethenoadenin ... Raadhika; Bian, Ke; Li, R01ES028865 07 20) Deyu; Delaney, Sarah Comprehensive Molecular Characterization Identifies Msaouel, Pavlos; P30ES030285, Cancer Cell (2020 05 11) 32359397 2020 Distinct Genomic and Immune Hallmarks of Renal M Malouf, Gabriel G; Su, R01ES029680 ... Xiaoping; Yao, Hui; Tripathi, Durga N; Soeung, Melinda ... Comprehensive structure-function characterization of Gao, Linfeng; Emperle, R35ES031707 Nat Commun (2020 07 03) 32620778 2020 DNMT3B and DNMT3A reveals distinctive de novo Max; Guo, Yiran; D ... Grimm, Sara A; Ren, Wendan; Adam, Sabrina; Uryu, Hide ... Cross-linking of the DNA repair protein Ming, Xun; R01ES023350 DNA Repair (Amst) (2020 32283495 2020 O6-alkylguanine DNA alkyltransferase to DNA in the Michaelson-Richie, Erin 05) presence ... D; Groehler 4th, Arnold S; Villalta, Peter W; Campbell, Coli ... Defective postreplication repair of UV photoproducts Brash, Douglas E; R01ES030562 Mol Oncol (2020 01) 31821728 2020 in melanoma: a mutator phenotype. Seidman, Michael M Detection and Discrimination of DNA Adducts Nookaew, Intawat; R01ES029749 Chem Res Toxicol (2020 32799528 2020 Differing in Size, Regiochemistry, and Functional Jenjaroenpun, Piroon; 12 21) Group ... Du, Hua; Wang, Pengcheng; Wu, Jun; Wongsurawat, Thidat ... Development of a DNA Adductome Mass Spectral Guo, Jingshu; Turesky, R01ES019564, Chem Res Toxicol (2020 32223224 2020 Database. Robert J; Tarifa, R03ES031188 04 20) Anamary; DeCaprio, Anthony P; Cooke, Marcus S; Walmsle ... DNA ligase I variants fail in the ligation of mutagenic Tang, Qun; Kamble, R00ES026191 Mutagenesis (2020 12 01) 32914844 2020 repair intermediates with mismatches and oxi ... Pradnya; Çağlayan, Melike DNA polymerase δ proofreads errors made by DNA Bulock, Chelsea R; R01ES015869 Proc Natl Acad Sci U S A 32123096 2020 polymerase ε. Xing, Xuanxuan; (2020 03 17) Shcherbakova, Polina V Dual genome-wide CRISPR knockout and CRISPR Schleicher, Emily M; R01ES026184 PLoS Genet (2020 11) 33137164 2020 activation screens identify mechanisms that regulate Dhoonmoon, Ashna; the ... Jackson, Lindsey M; Clements, Kristen E; Stump, Coryn L; ... Dynamic action of DNA repair proteins as revealed by Kong, Muwen; R35ES031638 DNA Repair (Amst) (2020 33087275 2020 single molecule techniques: Seeing is believing ... Beckwitt, Emily C; Van 09) Houten, Bennett Electron microscopic characterization of exhaust Griffith, Jack D R01ES031635 Atmos Pollut Res (2020 33100835 2020 particles containing lead dibromide beads expelled ... Sep) Engineered unnatural ubiquitin for optimal detection Rut, Wioletta; R01ES025166 Chem Sci (2020 Jun 21) 32953009 2020 of deubiquitinating enzymes. Zmudzinski, Mikolaj; Snipas, Scott J; Bekes, Miklos; Huang, Tony T; Drag, Marci ... Expanding molecular roles of UV-DDB: Shining light Beecher, Maria; Kumar, R35ES031638 DNA Repair (Amst) (2020 32739133 2020 on genome stability and cancer. Namrata; Jang, Sunbok; 10) Rapić-Otrin, Vesna; Van Houten, Bennett Exposure to microplastics cause gut damage, Zhang, Yan; Wolosker, R01ES027981 Sci Total Environ (2020 32721682 2020 locomotor dysfunction, epigenetic silencing, and Marina B; Zhao, Nov 20) aggrava ... Yanping; Ren, Hongqiang; Lemos, Bernardo Extracellular NAD+ enhances PARP-dependent DNA Wilk, Anna; Hayat, R01ES014811, Sci Rep (2020 01 20) 31959836 2020 repair capacity independently of CD73 activity. Faisal; Cunningham, U01ES029518, Richard; Li, Jianfeng; U01ES029518 Garavaglia, Silvia; Zamani, Leil ... EZH2 has a non-catalytic and PRC2-independent role Koyen, Allyson E; U01ES029520 Oncogene (2020 06) 32457468 2020 in stabilizing DDB2 to promote nucleotide excisio ... Madden, Matthew Z; Park, Dongkyoo; Minten, Elizabeth V; Kapoor-Vazirani, Priy ...
FANCJ compensates for RAP80 deficiency and Awate, Sanket; R01ES026184 Nucleic Acids Res (2020 32797166 2020 suppresses genomic instability induced by interstrand Sommers, Joshua A; 09 18) cro ... Datta, Arindam; Nayak, Sumeet; Bellani, Marina A; Yang, Oliv ... Functions of the major abasic endonuclease (APE1) in McNeill, Daniel R; R01ES029203 Mutagenesis (2020 02 13) 31816044 2020 cell viability and genotoxin resistance. Whitaker, Amy M; Stark, Wesley J; Illuzzi, Jennifer L; McKinnon, Peter J; Fr ... Genetically predicted telomere length is associated Brown, Derek W; Lin, DP2ES030554 PLoS Genet (2020 10) 33090998 2020 with clonal somatic copy number alterations in p ... Shu-Hong; Loh, Po-Ru; Chanock, Stephen J; Savage, Sharon A; Machiela, Mit ... Genome-wide CRISPR synthetic lethality screen Dhoonmoon, Ashna; R01ES026184 Nucleic Acids Res (2020 32542389 2020 identifies a role for the ADP-ribosyltransferase PARP1 Schleicher, Emily M; 07 27) ... Clements, Kristen E; Nicolae, Claudia M; Moldovan, Georg ... Genome-wide role of Rad26 in promoting Duan, Mingrui; Selvam, R01ES028698, Proc Natl Acad Sci U S A 32690696 2020 transcription-coupled nucleotide excision repair in Kathiresan; Wyrick, R21ES029655 (2020 08 04) yeast chr ... John J; Mao, Peng Genome-wide single-nucleotide resolution of Vaughn, Courtney M; R01ES027255 J Biol Chem (2020 05 29) 32299912 2020 oxaliplatin-DNA adduct repair in drug-sensitive and Selby, Christopher P; -res ... Yang, Yanyan; Hsu, David S; Sancar, Aziz Hematopoietic mosaic chromosomal alterations and Natarajan, Pradeep; DP2ES030554 Res Sq (2020 Nov 16) 33236004 2020 risk for infection among 767,891 individuals withou ... Zekavat, Seyedeh; Lin, Shu-Hong; Bick, Alexander; Liu, Aoxing; Paruchuri, ... Hematopoietic mosaic chromosomal alterations and Zekavat, Seyedeh M; DP2ES030554 medRxiv (2020 Nov 16) 33236019 2020 risk for infection among 767,891 individuals withou ... Lin, Shu-Hong; Bick, Alexander G; Liu, Aoxing; Paruchuri, Kaavya; Uddin, M ... History of DNA polymerase β X-ray crystallography. Whitaker, Amy M; R01ES029203 DNA Repair (Amst) (2020 33087265 2020 Freudenthal, Bret D 09) HLTF Promotes Fork Reversal, Limiting Replication Bai, Gongshi; Kermi, R01ES016486 Mol Cell (2020 06 18) 32442397 2020 Stress Resistance and Preventing Multiple Mechanis ... Chames; Stoy, Henriette; Schiltz, Carl J; Bacal, Julien; Zaino, Angela M; ... HMCES Maintains Replication Fork Progression and Mehta, Kavi P M; R01ES030575 Cell Rep (2020 06 02) 32492421 2020 Prevents Double-Strand Breaks in Response to Lovejoy, Courtney A; APOBEC ... Zhao, Runxiang; Heintzman, Darren R; Cortez, David Homologous Recombination Repair Truncations Lee, Minyi; Eng, R01ES015869 Clin Transl Gastroenterol 32352724 2020 Predict Hypermutation in Microsatellite Stable George; Barbari, (2020 03) Colorecta ... Stephanie R; Deshpande, Vikram; Shcherbakova, Polina V; Gala, ... Human XPG nuclease structure, assembly, and Tsutakawa, Susan E; R01ES031635 Proc Natl Acad Sci U S A 32522879 2020 activities with insights for neurodegeneration and Sarker, Altaf H; Ng, (2020 06 23) cance ... Clifford; Arvai, Andrew S; Shin, David S; Shih, Brian ... Hyperactive CDK2 Activity in Basal-like Breast Sviderskiy, Vladislav O; R01ES025166 Mol Cell (2020 11 19) 33152268 2020 Cancer Imposes a Genome Integrity Liability that Can Blumenberg, Lili; ... Gorodetsky, Elizabeth; Karakousi, Triantafyllia R; Hi ... Hypoxia Induces Resistance to EGFR Inhibitors in Lu, Yuhong; Liu, R01ES005775 Cancer Res (2020 11 01) 32873635 2020 Lung Cancer Cells via Upregulation of FGFR1 and the Yanfeng; Oeck, ... Sebastian; Zhang, Gary J; Schramm, Alexander; Glazer, Peter M Impact of 1,N6-ethenoadenosine, a damaged Ghodke, Pratibha P; R01ES026955 J Biol Chem (2020 05 01) 32213600 2020 ribonucleotide in DNA, on translesion synthesis and Guengerich, F Peter repair ... Impact of hypoxia on DNA repair and genome Kaplan, Alanna R; R01ES005775 Mutagenesis (2020 02 13) 31282537 2020 integrity. Glazer, Peter M Insights into the Direct Oxidative Repair of Etheno Lenz, Stefan A P; Li, R01ES028865, DNA Repair (Amst) (2020 33161373 2020 Lesions: MD and QM/MM Study on the Substrate Sco Deyu; Wetmore, Stacey R01ES028865 12) ... D Intergenerational transmission of childhood trauma? Etzel, Laura; Hastings, U01ES030949 Psychoneuroendocrinology 32629221 2020 Testing cellular aging in mothers exposed to sex ... Waylon J; Mattern, (2020 10) Brooke C; Oxford, Monica L; Heim, Christine; Putnam, ... Kinetic investigation of the polymerase and Zahurancik, Walter J; R01ES028271 J Biol Chem (2020 12 11) 33051204 2020 exonuclease activities of human DNA polymerase ε Suo, Zucai holoenz ... MCM8IP activates the MCM8-9 helicase to promote Huang, Jen-Wei; R01ES030335 Nat Commun (2020 06 11) 32528060 2020 DNA synthesis and homologous recombination upon Acharya, Ananya; DNA ... Taglialatela, Angelo; Nambiar, Tarun S; Cuella-Martin, Raquel; ... Methodologies for detecting environmentally induced Li, Wentao; Sancar, R01ES027255 Environ Mol Mutagen 32083352 2020 DNA damage and repair. Aziz (2020 08) Mismatch repair and DNA polymerase δ proofreading Bulock, Chelsea R; R01ES015869 Nucleic Acids Res (2020 32756902 2020 prevent catastrophic accumulation of leading stran ... Xing, Xuanxuan; 09 18) Shcherbakova, Polina V Mitochondrial dysfunction and DNA damage Nadalutti, Cristina A; R01ES031635 Sci Rep (2020 03 27) 32221313 2020 accompany enhanced levels of formaldehyde in Stefanick, Donna F; cultured prima ... Zhao, Ming-Lang; Horton, Julie K; Prasad, Rajendra; ... Molecular and structural characterization of Whitaker, Amy M; R01ES029203 DNA Repair (Amst) (2020 32454397 2020 disease-associated APE1 polymorphisms. Stark, Wesley J; Flynn, Jul - Aug) Tony S; Freudenthal, Bret D Molecular Mechanisms of Arsenic-Induced Disruption Tam, Lok Ming; Price, R01ES029749, Chem Res Toxicol (2020 31986875 2020 of DNA Repair. Nathan E; Wang, T32ES018827 03 16) Yinsheng Monogenic and polygenic inheritance become Loh, Po-Ru; Genovese, DP2ES030554 Nature (2020 08) 32581363 2020 instruments for clonal selection. Giulio; McCarroll, Steven A Mutagenesis mechanism of the major oxidative Koag, Myong-Chul; R01ES026676 Nucleic Acids Res (2020 32282906 2020 adenine lesion 7,8-dihydro-8-oxoadenine. Jung, Hunmin; Lee, 05 21) Seongmin NAD+-mediated regulation of mammalian base Saville, Kate M; Clark, P01ES028949, DNA Repair (Amst) (2020 33087267 2020 excision repair. Jennifer; Wilk, Anna; R01ES014811, 09) Rogers, Gresyn D; U01ES029518, Andrews, Joel F; U01ES029518 Koczor, Chris ... New insights into abasic site repair and tolerance. Thompson, Petria S; R01ES030575 DNA Repair (Amst) (2020 32417669 2020 Cortez, David 06) New insights into the regulation of DNA-Protein El Dika, Mohammed R01ES030575 DNA Repair (Amst) (2020 32330640 2020 Crosslink Repair by the Aspartic Protease Ddi1 in ye 06) ... Normalized retention time for scheduled liquid Gonzalez, Gwendolyn; R35ES031707, J Chromatogr A (2020 Jul 32505282 2020 chromatography-multistage mass spectrometry Cui, Yuxiang; Wang, T32ES018827 19) analysis ... Pengcheng; Wang, Yinsheng Nuclear and Cytoplasmic Functions of Vitamin C. Zhitkovich, Anatoly R01ES028072, Chem Res Toxicol (2020 33001635 2020 R01ES031002 10 19) Oncometabolites suppress DNA repair by disrupting Sulkowski, Parker L; R01ES005775 Nature (2020 06) 32494005 2020 local chromatin signalling. Oeck, Sebastian; Dow, Jonathan; Economos, Nicholas G; Mirfakhraie, Lily; L ... Pathogenic Mechanisms of Somatic Mutation and Vijg, Jan; Dong, Xiao U01ES029519 Cell (2020 07 09) 32649873 2020 Genome Mosaicism in Aging. Pharmacological methods to transcriptionally Kaplan, Alanna R; R01ES005775 Int Rev Cell Mol Biol 32475473 2020 modulate double-strand break DNA repair. Glazer, Peter M (2020) Pol β gap filling, DNA ligation and substrate-product Çağlayan, Melike R00ES026191 DNA Repair (Amst) (2020 32853828 2020 channeling during base excision repair opposit ... 11) Pol μ ribonucleotide insertion opposite 8-oxodG Çağlayan, Melike R00ES026191 Sci Rep (2020 01 22) 31969622 2020 facilitates the ligation of premutagenic DNA repair ... POLE Mutation Spectra Are Shaped by the Mutant Hodel, Karl P; Sun, R01ES028271 Mol Cell (2020 06 18) 32497495 2020 Allele Identity, Its Abundance, and Mismatch Repair S Meijuan J S; ... Ungerleider, Nathan; Park, Vivian S; Williams, Leonard G; Baue ... Promutagenic bypass of 7,8-dihydro-8-oxoadenine by Jung, Hunmin; Lee, R01ES026676 Biochem J (2020 08 14) 32686822 2020 translesion synthesis DNA polymerase Dpo4. Seongmin Proteome-wide Interrogation of Small GTPases Yang, Yen-Yu; Yu, R35ES031707, Anal Chem (2020 07 21) 32567849 2020 Regulated by N6-Methyladenosine Modulators. Kailin; Li, Lin; Huang, T32ES018827 Ming; Wang, Yinsheng RAD51 Gene Family Structure and Function. Bonilla, Braulio; R01ES030335 Annu Rev Genet (2020 11 32663049 2020 Hengel, Sarah R; 23) Grundy, McKenzie K; Bernstein, Kara A Rad54 and Rdh54 occupy spatially and functionally Crickard, J Brooks; R01ES007061 EMBO J (2020 10 15) 32790929 2020 distinct sites within the Rad51-ssDNA presynaptic ... Kwon, Youngho; Sung, Patrick; Greene, Eric C Rad54 Drives ATP Hydrolysis-Dependent DNA Crickard, J Brooks; R01ES007061 Cell (2020 06 11) 32502392 2020 Sequence Alignment during Homologous Moevus, Corentin J; Recombination. Kwon, Youngho; Sung, Patrick; Greene, Eric C Radiation Treatment, ATM, BRCA1/2, and Reiner, Anne S; R01ES027121 J Natl Cancer Inst (2020 32119081 2020 CHEK2*1100delC Pathogenic Variants and Risk of Robson, Mark E; 12 14) Contralateral ... Mellemkjær, Lene; Tischkowitz, Marc; John, Esther M; Lynch, Ch ... Recognition of DNA adducts by edited and unedited Minko, Irina G; R01ES029357, DNA Repair (Amst) (2020 31733589 2020 forms of DNA glycosylase NEIL1. Vartanian, Vladimir L; R01ES031086 01) Tozaki, Naoto N; Coskun, Erdem; Coskun, Sanem Hosbas; Ja ... Regulation and pharmacological targeting of RAD51 Grundy, McKenzie K; R01ES030335 NAR Cancer (2020 Sep) 33015624 2020 in cancer. Buckanovich, Ronald J; Bernstein, Kara A REV1 inhibitor JH-RE-06 enhances tumor cell Chatterjee, Nimrat; P30ES002109, Proc Natl Acad Sci U S A 33168727 2020 response to chemotherapy by triggering senescence Whitman, Matthew A; R35ES028303 (2020 11 17) hallma ... Harris, Cynthia A; Min, Sophia M; Jonas, Oliver; Lien, ... Rev7 loss alters cisplatin response and increases drug Vassel, Faye-Marie; P30ES002109, Proc Natl Acad Sci U S A 33144509 2020 efficacy in chemotherapy-resistant lung cance ... Bian, Ke; Walker, R35ES028303, (2020 11 17) Graham C; Hemann, T32ES007020 Michael T Ribonucleotide incorporation in yeast genomic DNA Balachander, Sathya; R01ES026243 Nat Commun (2020 05 15) 32415081 2020 shows preference for cytosine and guanosine preced ... Gombolay, Alli L; Yang, Taehwan; Xu, Penghao; Newnam, Gary; Keskin, Havva ... Roles for MDC1 in cancer development and treatment. Ruff, Sophie E; Logan, R01ES025166 DNA Repair (Amst) (2020 32866776 2020 Susan K; Garabedian, 11) Michael J; Huang, Tony T Single-molecule live-cell imaging reveals Henrikus, Sarah S; R35ES028343 Nucleic Acids Res (2020 32687193 2020 RecB-dependent function of DNA polymerase IV Henry, Camille; 09 04) in double str ... McGrath, Amy E; Jergic, Slobodan; McDonald, John P; Hellmich ... Specificity of end resection pathways for Daley, James M; R01ES007061 Nat Commun (2020 06 18) 32555206 2020 double-strand break regions containing ribonucleotides Tomimatsu, Nozomi; and ... Hooks, Grace; Wang, Weibin; Miller, Adam S; Xue, Xiaoyu; Ng ... Structural basis for STAT2 suppression by flavivirus Wang, Boxiao; R35ES031707 Nat Struct Mol Biol (2020 32778820 2020 NS5. Thurmond, Stephanie; 10) Zhou, Kang; Sánchez-Aparicio, Maria T; Fang, Jian; Lu, Jiuw ... Structural biology of DNA abasic site protection by Amidon, Katherine M; F31ES032334, DNA Repair (Amst) (2020 32663791 2020 SRAP proteins. Eichman, Brandt F R01ES030575 10) Structural insights into the bypass of the major Jung, Hunmin; R01ES026676 Biochem J (2020 12) 33258913 2020 deaminated purines by translesion synthesis DNA pol Hawkins, Michael; Lee, ... Seongmin Structural insights into the promutagenic bypass of the Ouzon-Shubeita, Hala; R01ES026676 Biochem J (2020 03 13) 32039434 2020 major cisplatin-induced DNA lesion. Vilas, Caroline K; Lee, Seongmin Tethering-facilitated DNA 'opening' and Paul, Debamita; Mu, R01ES025987 Nucleic Acids Res (2020 33119737 2020 complementary roles of β-hairpin motifs in the Hong; Tavakoli, 12 02) Rad4/XPC DNA ... Amirrasoul; Dai, Qing; Chen, Xuejing; Chakraborty, Sagnik; ... The antitumorigenic roles of BRCA1-BARD1 in DNA Tarsounas, Madalena; R01ES007061 Nat Rev Mol Cell Biol 32094664 2020 repair and replication. Sung, Patrick (2020 05) The circadian clock shapes the Arabidopsis Yang, Yuchen; Li, Yun; R01ES027255 J Biol Chem (2020 05 29) 32303634 2020 transcriptome by regulating alternative splicing and Sancar, Aziz; Oztas, alte ... Onur The DNA damage-sensing NER repair factor Feher, Katie M; R01ES025987 DNA Repair (Amst) (2020 33035795 2020 XPC-RAD23B does not recognize bulky DNA lesions Kolbanovskiy, 12) with a miss ... Alexander; Durandin, Alexander; Shim, Yoonjung; Min, Jung-Hyun; L ... The DNA-binding activity of USP1-associated factor 1 Liang, Fengshan; Miller, R01ES007061 J Biol Chem (2020 06 12) 32350107 2020 is required for efficient RAD51-mediated homolo ... Adam S; Tang, Caroline; Maranon, David; Williamson, Elizabeth A; Hroma ... The involvement of nucleotide excision repair proteins Kumar, Namrata; Raja, R35ES031638 Nucleic Acids Res (2020 33010169 2020 in the removal of oxidative DNA damage. Sripriya; Van Houten, 11 18) Bennett The ligation of pol β mismatch insertion products Çağlayan, Melike R00ES026191 Nucleic Acids Res (2020 32140717 2020 governs the formation of promutagenic base excisio ... 04 17)
The roles of polymerases ν and θ in replicative bypass Du, Hua; Wang, R01ES029749 J Biol Chem (2020 04 03) 32098870 2020 of O 6- and N 2-alkyl-2'-deoxyguanosine lesio ... Pengcheng; Wu, Jun; He, Xiaomei; Wang, Yinsheng Translesion synthesis of 6-nitrochrysene-derived Powell, Brent V; R01ES023350 DNA Repair (Amst) (2020 32721818 2020 2'-deoxyadenosine adduct in human cells. Bacurio, Jan Henric T; 11) Basu, Ashis K Translesion synthesis of the major nitrogen Jung, Hunmin; Rayala, R01ES026676 Biochem J (2020 12 11) 33175093 2020 mustard-induced DNA lesion by human DNA Naveen Kumar; Lee, polymerase η. Seongmin Tumor-Targeted, Cytoplasmic Delivery of Large, Svoronos, Alexander A; R01ES005775 Mol Pharm (2020 02 03) 31855437 2020 Polar Molecules Using a pH-Low Insertion Peptide. Bahal, Raman; Pereira, Mohan C; Barrera, Francisco N; Deacon, John C; Bo ... Ubiquitinated-PCNA protects replication forks from Thakar, Tanay; Leung, R01ES026184 Nat Commun (2020 05 01) 32358495 2020 DNA2-mediated degradation by regulating Okazaki f Wendy; Nicolae, ... Claudia M; Clements, Kristen E; Shen, Binghui; Bielinsky, ... Unhooking of an interstrand cross-link at DNA fork Imani Nejad, Maryam; R01ES021007 DNA Repair (Amst) (2020 31923807 2020 structures by the DNA glycosylase NEIL3. Housh, Kurt; Rodriguez, 02) Alyssa A; Haldar, Tuhin; Kathe, Scott; Wallace, S ... Uninterruptible Power Supply Improves Precision and Hastings, Waylon J; U01ES030949 Exp Results (2020) 33718773 2020 External Validity of Telomere Length Measurement ... Eisenberg, Dan T A; Shalev, Idan Variable impact of conformationally distinct DNA Cai, Yuqin; Geacintov, R01ES025987 DNA Repair (Amst) (2020 32018112 2020 lesions on nucleosome structure and dynamics: Impli Nicholas E; Broyde, 03) ... Suse VEZF1-guanine quadruplex DNA interaction Li, Lin; Williams, R35ES031707 Nucleic Acids Res (2020 33231681 2020 regulates alternative polyadenylation and detyrosinase Preston; Gao, Zi; Wang, 12 02) acti ... Yinsheng YTHDF2 Binds to 5-Methylcytosine in RNA and Dai, Xiaoxia; Gonzalez, R01ES025121, Anal Chem (2020 01 07) 31815440 2020 Modulates the Maturation of Ribosomal RNA. Gwendolyn; Li, Lin; Li, T32ES018827 Jie; You, Changjun; Miao, Weili; Hu, Junchi; ... 5-Formylcytosine-induced DNA-peptide cross-links Ji, Shaofei; Park, R01ES023350, J Biol Chem (2019 11 29) 31597704 2019 reduce transcription efficiency, but do not cause t ... Daeyoon; Kropachev, R01ES025987 Konstantin; Kolbanovskiy, Marina; Fu, Iwen; Broyde, Sus ... A parametric meta-analysis. Yu, Chang; Zelterman, R01ES005775 Stat Med (2019 09 20) 31206759 2019 Daniel A recurrent cancer-associated substitution in DNA Xing, Xuanxuan; Kane, R01ES015869 Nat Commun (2019 01 22) 30670691 2019 polymerase ε produces a hyperactive enzyme. Daniel P; Bulock, Chelsea R; Moore, Elizabeth A; Sharma, Sushma; Chabes, ... A Small Molecule Targeting Mutagenic Translesion Wojtaszek, Jessica L; R01ES028865, Cell (2019 06 27) 31178121 2019 Synthesis Improves Chemotherapy. Chatterjee, Nimrat; R01ES028865, Najeeb, Javaria; Ramos, R35ES028303 Azucena; Lee, Minhee; Bian, ... A two-stage phase II clinical trial design with nested DeVeaux, Michelle; R01ES005775 Pharm Stat (2019 11) 31507079 2019 criteria for early stopping and efficacy. Kane, Michael; Wei, Wei; Zelterman, Daniel A White-Box Machine Learning Approach for Yang, Jason H; Wright, R35ES028303 Cell (2019 05 30) 31080069 2019 Revealing Antibiotic Mechanisms of Action. Sarah N; Hamblin, Meagan; McCloskey, Douglas; Alcantar, Miguel A; Schrüb ... Aberrant Activation of β-Catenin Signaling Drives Ma, Li; Lin, Kangyu; R01ES025166 Cancer Res (2019 01 01) 30425057 2019 Glioma Tumorigenesis via USP1-Mediated Stabilizati Chang, Guoqiang; Chen, ... Yiwen; Yue, Chen; Guo, Qing; Zhang, Sicong; Jia, ... Accelerating cancer without mutations. Brash, Douglas E R01ES030562 Elife (2019 03 21) 30895924 2019 Addendum: Ribose-seq: global mapping of Koh, Kyung Duk; R01ES026243 Nat Methods (2019 08) 31324896 2019 ribonucleotides embedded in genomic DNA. Balachander, Sathya; Hesselberth, Jay R; Storici, Francesca Aflatoxin-Guanine DNA Adducts and Oxidatively Coskun, Erdem; Jaruga, R01ES029357, Chem Res Toxicol (2019 30525498 2019 Induced DNA Damage in Aflatoxin-Treated Mice in Pawel; Vartanian, R01ES031086 01 22) Vivo a ... Vladimir; Erdem, Onur; Egner, Patricia A; Groopman, J ... AID-RNA polymerase II transcription-dependent Pham, Phuong; Malik, R35ES028343 Nucleic Acids Res (2019 31566237 2019 deamination of IgV DNA. Sohail; Mak, Chiho; 11 18) Calabrese, Peter C; Roeder, Robert G; Goodman, Myron ... Association of a Pathway-Specific Genetic Risk Score Watt, Gordon P; Reiner, R01ES027121 JAMA Netw Open (2019 31560388 2019 With Risk of Radiation-Associated Contralateral ... Anne S; Smith, Susan 09 04) A; Stram, Daniel O; Capanu, Marinela; Malone, Kat ... Bioactivation of the tobacco carcinogens Bellamri, Medjda; Yao, R01ES019564, Arch Toxicol (2019 07) 31203411 2019 4-aminobiphenyl (4-ABP) and Lihua; Bonala, Radha; R01ES030559 2-amino-9H-pyrido[2,3-b]indole ... Johnson, Francis; Von Weymarn, Linda B; Turesky, ... Biological Evaluation of DNA Biomarkers in a Bian, Ke; Delaney, R01ES028865, Toxics (2019 Jun 25) 31242562 2019 Chemically Defined and Site-Specific Manner. James C; Zhou, R01ES028865 Xianhao; Li, Deyu Bypass of the Major Alkylative DNA Lesion by Koag, Myong-Chul; R01ES026676 Molecules (2019 Oct 31) 31683505 2019 Human DNA Polymerase η. Jung, Hunmin; Kou, Yi; Lee, Seongmin Capture of Ribonucleotides in Yeast Genomic DNA Balachander, Sathya; R01ES026243 Methods Mol Biol (2019) 31602603 2019 Using Ribose-Seq. Yang, Taehwan; Newnam, Gary; El-Sayed, Waleed M M; Koh, Kyung Duk; Storici ... Cediranib suppresses homology-directed DNA repair Kaplan, Alanna R; R01ES005775 Sci Transl Med (2019 05 31092693 2019 through down-regulation of BRCA1/2 and RAD51. Gueble, Susan E; Liu, 15) Yanfeng; Oeck, Sebastian; Kim, Hoon; Yun, Zhong; Glaze ... Characterization of rare NEIL1 variants found in East Minko, Irina G; R01ES029357 DNA Repair (Amst) (2019 31100703 2019 Asian populations. Vartanian, Vladimir L; 07) Tozaki, Naoto N; Linde, Oskar K; Jaruga, Pawel; Coskun, ... Conformational regulation of Escherichia coli DNA Jaszczur, Malgorzata M; R35ES028343 PLoS Genet (2019 02) 30716079 2019 polymerase V by RecA and ATP. Vo, Dan D; Stanciauskas, Ramunas; Bertram, Jeffrey G; Sikand, Adhirath; ... Ddc2ATRIP promotes Mec1ATR activation at Biswas, Himadri; Goto, R01ES007061 PLoS Genet (2019 08) 31369547 2019 RPA-ssDNA tracts. Greicy; Wang, Weibin; Sung, Patrick; Sugimoto, Katsunori Defining the influence of Rad51 and Dmc1 Steinfeld, Justin B; R01ES007061 Genes Dev (2019 09 01) 31371435 2019 lineage-specific amino acids on genetic recombination. Beláň, Ondrej; Kwon, Youngho; Terakawa, Tsuyoshi; Al-Zain, Amr; Smith, Mi ... Differential damage and repair of DNA-adducts Yimit, Askar; Adebali, P30ES010126, Nat Commun (2019 01 18) 30659176 2019 induced by anti-cancer drug cisplatin across mouse org Ogun; Sancar, Aziz; R01ES027255 ... Jiang, Yuchao DNA Crosslinkomics: A Tool for the Comprehensive Hu, Chiung-Wen; R01ES030557 Anal Chem (2019 12 03) 31670503 2019 Assessment of Interstrand Crosslinks Using High Res Chang, Yuan-Jhe; ... Cooke, Marcus S; Chao, Mu-Rong DNA methylation modifications induced by Guo, Xinnian; Feng, R01ES027981 J Environ Sci Health C 31084241 2019 hexavalent chromium. Lingfang; Lemos, Environ Carcinog Bernardo; Lou, Jianlin Ecotoxicol Rev (2019) DNA repair enzymes ALKBH2, ALKBH3, and AlkB Bian, Ke; Lenz, Stefan P30ES002109, Nucleic Acids Res (2019 31114894 2019 oxidize 5-methylcytosine to 5-hydroxymethylcytosine, A P; Tang, Qi; Chen, R01ES028865, 06 20) 5-f ... Fangyi; Qi, Rui; Jost, R01ES028865 Marco; Drennan, Catherine ... DNA replication studies of N-nitroso Wang, Pengcheng; R01ES025121 J Biol Chem (2019 03 15) 30655287 2019 compound-induced O6-alkyl-2'-deoxyguanosine Leng, Jiapeng; Wang, lesions in Escheric ... Yinsheng DNA requirement in FANCD2 deubiquitination by Liang, Fengshan; Miller, R01ES007061 Nat Commun (2019 06 28) 31253762 2019 USP1-UAF1-RAD51AP1 in the Fanconi anemia DNA Adam S; Longerich, damage re ... Simonne; Tang, Caroline; Maranon, David; Williamson ... Drosophila, which lacks canonical Deger, Nazli; Yang, R01ES027255 J Biol Chem (2019 11 29) 31624146 2019 transcription-coupled repair proteins, performs Yanyan; Lindsey-Boltz, transcription-coup ... Laura A; Sancar, Aziz; Selby, Christopher P Dual regulation of Arabidopsis AGO2 by arginine Hu, Po; Zhao, Hongwei; R01ES025121 Nat Commun (2019 02 19) 30783097 2019 methylation. Zhu, Pei; Xiao, Yongsheng; Miao, Weili; Wang, Yinsheng; Jin, Hailing Dynamic interactions of the homologous pairing 2 Crickard, J Brooks; R01ES007061 J Biol Chem (2019 01 11) 30420424 2019 (Hop2)-meiotic nuclear divisions 1 (Mnd1) protein c Kwon, Youngho; Sung, ... Patrick; Greene, Eric C Error-prone replication of a Naldiga, Spandana; Ji, R01ES023350, J Biol Chem (2019 07 05) 31138652 2019 5-formylcytosine-mediated DNA-peptide cross-link in Shaofei; Thomforde, R01ES026184 human cells. Jenna; Nicolae, Claudia M; Lee, Marietta; Zhang, Zh ... Evaluation of the Major Steps in the Conventional Karbaschi, Mahsa; Ji, R41ES030274 Int J Mol Sci (2019 Dec 31810189 2019 Protocol for the Alkaline Comet Assay. Yunhee; Abdulwahed, 02) Abdulhadi Mohammed S; Alohaly, Alhanoof; Bedoya, Juan ... Exposure to an environmentally relevant phthalate Scarano, Wellerson R; R01ES027981 Toxicol Sci (2019 Jun 14) 31199487 2019 mixture during prostate development induces microR Bedrat, Amina; ... Alonso-Costa, Luiz G; Aquino, Ariana M; Fantinatti, Bruno; ... Genetic predisposition to mosaic Y chromosome loss Thompson, Deborah J; DP2ES030554 Nature (2019 11) 31748747 2019 in blood. Genovese, Giulio; Halvardson, Jonatan; Ulirsch, Jacob C; Wright, Daniel J; ... Genome-wide mapping of nucleotide excision repair Hu, Jinchuan; Li, P30ES010126, Nat Protoc (2019 01) 30552409 2019 with XR-seq. Wentao; Adebali, Ogun; R01ES027255 Yang, Yanyan; Oztas, Onur; Selby, Christopher P; Sanc ... Genomic sites hypersensitive to ultraviolet radiation. Premi, Sanjay; Han, R01ES030562 Proc Natl Acad Sci U S A 31723047 2019 Lynn; Mehta, Sameet; (2019 11 26) Knight, James; Zhao, Dejian; Palmatier, Meg A; Kornac ... Guidelines for DNA recombination and repair studies: Klein, Hannah L; Ang, R01ES007061 Microb Cell (2019 Jan 07) 30652106 2019 Mechanistic assays of DNA repair processes. Kenny K H; Arkin, Michelle R; Beckwitt, Emily C; Chang, Yi-Hsuan; Fan, J ... GWAS of mosaic loss of chromosome Y highlights Terao, Chikashi; DP2ES030554 Nat Commun (2019 10 17) 31624269 2019 genetic effects on blood cell differentiation. Momozawa, Yukihide; Ishigaki, Kazuyoshi; Kawakami, Eiryo; Akiyama, Masato; Loh ... High-throughput Evaluation of Protein Migration and Oeck, Sebastian; R01ES005775 Sci Rep (2019 02 28) 30816253 2019 Localization after Laser Micro-Irradiation. Malewicz, Nathalie M; Krysztofiak, Adam; Turchick, Audrey; Jendrossek, Verena; ... Human DNA polymerase η has reverse transcriptase Su, Yan; Ghodke, R01ES010546, J Biol Chem (2019 04 12) 30842261 2019 activity in cellular environments. Pratibha P; Egli, Martin; R01ES025121, Li, Lin; Wang, R01ES026955, Yinsheng; Guengerich, R01ES029357 F Peter Hydrolyzable Tannins Are Iron Chelators That Inhibit Chen, Fangyi; Tang, Qi; R01ES028865, Chem Res Toxicol (2019 31088072 2019 DNA Repair Enzyme ALKBH2. Ma, Hang; Bian, Ke; R01ES028865 06 17) Seeram, Navindra P; Li, Deyu Interplay between DNA Polymerases and DNA Çağlayan, Melike R00ES026191 J Mol Biol (2019 05 17) 31034893 2019 Ligases: Influence on Substrate Channeling and the Fidelit ... Long-term, genome-wide kinetic analysis of the effect Yang, Yanyan; Liu, P30ES010126, J Biol Chem (2019 08 09) 31217280 2019 of the circadian clock and transcription on th ... Zhenxing; Selby, R01ES027255 Christopher P; Sancar, Aziz Mechanisms of MTH1 inhibition-induced DNA strand Rai, Priyamvada; Sobol, P01ES028949, DNA Repair (Amst) (2019 30852368 2019 breaks: The slippery slope from the oxidized nucleo ... Robert W R01ES014811, 05) U01ES029518, U01ES029518 Mechanisms underlying aflatoxin-associated McCullough, Amanda R01ES029357 DNA Repair (Amst) (2019 30897375 2019 mutagenesis - Implications in carcinogenesis. K; Lloyd, R Stephen 05) Mechanistic Study of TTF-1 Modulation of Cellular Phelps, Cody A; P30ES010126, Sci Rep (2019 05 29) 31142791 2019 Sensitivity to Cisplatin. Lindsey-Boltz, Laura; R01ES027255 Sancar, Aziz; Mu, David MiR223-3p promotes synthetic lethality in Srinivasan, Gayathri; R01ES007061 Proc Natl Acad Sci U S A 31395736 2019 BRCA1-deficient cancers. Williamson, Elizabeth (2019 08 27) A; Kong, Kimi; Jaiswal, Aruna S; Huang, Guangcun; K ... Mitochondrial DNA: Epigenetics and environment. Sharma, Nidhi; Pasala, R01ES030084, Environ Mol Mutagen 31335990 2019 Monica S; Prakash, R01ES030084 (2019 10) Aishwarya Murine models of accelerated aging and Hambright, William S; U01ES029603 Bone (2019 08) 30844492 2019 musculoskeletal disease. Niedernhofer, Laura J; Huard, Johnny; Robbins, Paul D Mutagenic Replication of the Major Oxidative Koag, Myong-Chul; R01ES026676 J Am Chem Soc (2019 03 30817143 2019 Adenine Lesion 7,8-Dihydro-8-oxoadenine by Human Jung, Hunmin; Lee, 20) DNA Po ... Seongmin N-Acetylcysteine: Antioxidant, Aldehyde Scavenger, Zhitkovich, Anatoly R01ES028072 Chem Res Toxicol (2019 31046246 2019 and More. 07 15) NuA4 acetyltransferase is required for efficient Hodges, Amelia J; R01ES028698 DNA Repair (Amst) (2019 30473425 2019 nucleotide excision repair in yeast. Plummer, Dalton A; 01) Wyrick, John J Nucleotide Excision Repair and Impact of Shafirovich, Vladimir; R01ES025987 Biochemistry (2019 02 12) 30570250 2019 Site-Specific 5',8-Cyclopurine and Bulky DNA Kolbanovskiy, Marina; Lesions on the ... Kropachev, Konstantin; Liu, Zhi; Cai, Yuquin; Terz ... Nucleotide excision repair capacity increases during Li, Wentao; Liu, P30ES010126, J Biol Chem (2019 04 12) 30808711 2019 differentiation of human embryonic carcinoma ce ... Wenjie; Kakoki, Ayano; R01ES027255 Wang, Rujin; Adebali, Ogun; Jiang, Yuchao; Sancar, Az ... Organization of DNA damage, excision repair, and Mao, Peng; Wyrick, R01ES028698, DNA Repair (Amst) (2019 31307926 2019 mutagenesis in chromatin: A genomic perspective. John J R21ES029655 09) Oxidative Cyclization-Induced Activation of a Zhu, Haizhou; Mishra, R15ES029675, ChemMedChem (2019 11 31696673 2019 Phosphoinositide 3-Kinase Inhibitor for Enhanced Rosalin; Yuan, Long; R15ES029675 20) Selec ... Abdul Salam, Safnas F; Liu, Jing; Gray, George; Ste ... p53 activation by Cr(VI): a transcriptionally limited Luczak, Michal W; R01ES028072 Toxicol Sci (2019 Aug 06) 31388677 2019 response induced by ATR kinase in S-phase. Krawic, Casey; Zhitkovich, Anatoly POLE proofreading defects: Contributions to Park, Vivian S; Pursell, R01ES028271 DNA Repair (Amst) (2019 30818169 2019 mutagenesis and cancer. Zachary F 04) Probing the Effect of Bulky Lesion-Induced Cai, Ang; Bian, Ke; R01ES028865, Molecules (2019 Apr 20) 31009995 2019 Replication Fork Conformational Heterogeneity Using Chen, Fangyi; Tang, Qi; R01ES028865 4-Ami ... Carley, Rachel; Li, Deyu; Cho, Bongsup P Processing of N5-substituted formamidopyrimidine Minko, Irina G; R01ES029357 DNA Repair (Amst) (2019 30448017 2019 DNA adducts by DNA glycosylases NEIL1 and Christov, Plamen P; Li, 01) NEIL3. Liang; Stone, Michael P; McCullough, Amanda K; Lloyd, ... Promutagenicity of 8-Chloroguanine, A Major Kou, Yi; Koag, R01ES026676 Molecules (2019 Sep 27) 31569643 2019 Inflammation-Induced Halogenated DNA Lesion. Myong-Chul; Lee, Seongmin Protection of abasic sites during DNA replication by a Thompson, Petria S; R01ES030575 Nat Struct Mol Biol (2019 31235915 2019 stable thiazolidine protein-DNA cross-link. Amidon, Katherine M; 07) Mohni, Kareem N; Cortez, David; Eichman, Brandt F Quantification of DNA Lesions Induced by Guo, Su; Leng, Jiapeng; R01ES025121, Chem Res Toxicol (2019 30714728 2019 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol in Tan, Ying; Price, T32ES018827 04 15) Mammalian ... Nathan E; Wang, Yinsheng R-loop formation by dCas9 is mutagenic in Laughery, Marian F; R01ES028698 Nucleic Acids Res (2019 30590793 2019 Saccharomyces cerevisiae. Mayes, Hannah C; 03 18) Pedroza, Ivan K; Wyrick, John J Rad52 Restrains Resection at DNA Double-Strand Yan, Zhenxin; Xue, R01ES007061 Mol Cell (2019 12 05) 31542296 2019 Break Ends in Yeast. Chaoyou; Kumar, Sandeep; Crickard, J Brooks; Yu, Yang; Wang, Weibin; Pham, ...
Random Walk Enzymes: Information Theory, Mak, Chi H; Pham, R35ES028343 J Phys Chem A (2019 Apr 30848911 2019 Quantum Isomorphism, and Entropy Dispersion. Phuong; Goodman, 04) Myron F Recurrent Noncoding Mutations in Skin Cancers: UV Roberts, Steven A; R01ES028698 Bioessays (2019 03) 30801747 2019 Damage Susceptibility or Repair Inhibition as Prim ... Brown, Alexander J; Wyrick, John J Regulatory control of Sgs1 and Dna2 during Xue, Chaoyou; Wang, R01ES007061 Proc Natl Acad Sci U S A 30850524 2019 eukaryotic DNA end resection. Weibin; Crickard, J (2019 03 26) Brooks; Moevus, Corentin J; Kwon, Youngho; Sung, Patri ... Repair and translesion synthesis of O6-alkylguanine Du, Hua; Wang, R01ES025121 J Biol Chem (2019 07 19) 31167778 2019 DNA lesions in human cells. Pengcheng; Li, Lin; Wang, Yinsheng Replication-Coupled DNA Repair. Cortez, David R01ES030575 Mol Cell (2019 06 06) 31173722 2019 Ribose-Map: a bioinformatics toolkit to map Gombolay, Alli L; R01ES026243 Nucleic Acids Res (2019 30272244 2019 ribonucleotides embedded in genomic DNA. Vannberg, Fredrik O; 01 10) Storici, Francesca Ribosomal DNA and the Nucleolus as Keystones of Cerqueira, Amanda V; R01ES027981 Trends Genet (2019 10) 31447250 2019 Nuclear Architecture, Organization, and Function. Lemos, Bernardo Ribosomal DNA harbors an evolutionarily conserved Wang, Meng; Lemos, P30ES000002, Genome Res (2019 03) 30765617 2019 clock of biological aging. Bernardo R01ES027981 Role of RNase H enzymes in maintaining genome Walsh, Erin; Henrikus, R35ES028343 DNA Repair (Amst) (2019 31543434 2019 stability in Escherichia coli expressing a steric-gate ... Sarah S; Vaisman, 12) Alexandra; Makiela-Dzbenska, Karolina; Armstrong, Thom ... Role of Y-family translesion DNA polymerases in Tonzi, Peter; Huang, R01ES025166 DNA Repair (Amst) (2019 30954011 2019 replication stress: Implications for new cancer ther ... Tony T 06) Rotational and translational positions determine the Fu, Iwen; Smith, R01ES025987 DNA Repair (Amst) (2019 30522887 2019 structural and dynamic impact of a single ribon ... Duncan J; Broyde, Suse 01) Sense and sensibility: ATM oxygen stress signaling Schlacher, Katharina R01ES029680 J Cell Biol (2019 03 04) 30782782 2019 manages brain cell energetics. Simple CRISPR-Cas9 Genome Editing in Laughery, Marian F; R01ES028698, Curr Protoc Mol Biol 31763795 2019 Saccharomyces cerevisiae. Wyrick, John J R21ES029655 (2019 12) Single-molecule visualization of human BLM helicase Xue, Chaoyou; Daley, R01ES007061 Nucleic Acids Res (2019 31544923 2019 as it acts upon double- and single-stranded DNA ... James M; Xue, Xiaoyu; 12 02) Steinfeld, Justin; Kwon, Youngho; Sung, Patrick; Gr ... Single-nucleotide resolution analysis of nucleotide Yang, Yanyan; Hu, P30ES010126, J Biol Chem (2019 01 04) 30413533 2019 excision repair of ribosomal DNA in humans and m ... Jinchuan; Selby, R01ES027255 Christopher P; Li, Wentao; Yimit, Askar; Jiang, Yuchao; San ... SLIRP Interacts with Helicases to Facilitate Li, Lin; Miao, Weili; R01ES025121 J Am Chem Soc (2019 07 31260285 2019 2'-O-Methylation of rRNA and to Promote Translation. Williams, Preston; Guo, 17) Cheng; Wang, Yinsheng
Structural basis for the bypass of the major Ouzon-Shubeita, Hala; R01ES026676 Biochem J (2019 02 28) 30709915 2019 oxaliplatin-DNA adducts by human DNA polymerase Baker, Meghan; Koag, η. Myong-Chul; Lee, Seongmin Structural consequence of the most frequently Parkash, Vimal; R01ES015869 Nat Commun (2019 01 22) 30670696 2019 recurring cancer-associated substitution in DNA Kulkarni, Yashraj; Ter polyme ... Beek, Josy; Shcherbakova, Polina V; Kamerlin, Shina Caro ... Structure and mechanism of pyrimidine-pyrimidone Paul, Debamita; Mu, R01ES025987 Nucleic Acids Res (2019 31106376 2019 (6-4) photoproduct recognition by the Rad4/XPC nucl Hong; Zhao, Hong; 07 09) ... Ouerfelli, Ouathek; Jeffrey, Philip D; Broyde, Suse; Min ... Synthesis and Characterization of Site-Specific O6 Ghodke, Pratibha P; R01ES010546, Curr Protoc Nucleic Acid 30657645 2019 -Alkylguanine DNA-Alkyl Transferase-Oligonucleoti Albertolle, Matthew E; R01ES026955, Chem (2019 03) ... Johnson, Kevin M; T32ES007028 Guengerich, F Peter Targeted and Persistent 8-Oxoguanine Base Damage at Fouquerel, Elise; R00ES027028 Mol Cell (2019 07 11) 31101499 2019 Telomeres Promotes Telomere Loss and Crisis. Barnes, Ryan P; Uttam, Shikhar; Watkins, Simon C; Bruchez, Marcel P; Opresko, ... Targeted Quantitative Proteomic Approach for Huang, Ming; Darvas, R01ES025121, Anal Chem (2019 10 01) 31460748 2019 High-Throughput Quantitative Profiling of Small Martin; Keene, C Dirk; T32ES018827 GTPases ... Wang, Yinsheng Targeted Quantitative Proteomics Revealed Tam, Lok Ming; Huang, R01ES025121, Chem Res Toxicol (2019 31140275 2019 Arsenite-induced Proteasomal Degradation of RhoB in Ming; Wang, Yinsheng T32ES018827 07 15) Fibrob ... Targeting phosphatases in cancer: suppression of many D'Arcy, Brandon M; R01ES030084, Oncotarget (2019 Nov 12) 31762936 2019 versus the ablation of one. Prakash, Aishwarya; R01ES030084 Honkanen, Richard E The BRCA Tumor Suppressor Network in Zhao, Weixing; Wiese, R01ES007061 Annu Rev Biochem (2019 30917004 2019 Chromosome Damage Repair by Homologous Claudia; Kwon, 06 20) Recombination. Youngho; Hromas, Robert; Sung, Patrick The Impact of Minor-Groove Wu, Jun; Du, Hua; Li, R01ES025121, ACS Chem Biol (2019 08 31347832 2019 N2-Alkyl-2'-deoxyguanosine Lesions on DNA Lin; Price, Nathan E; T32ES018827 16) Replication in Human Cells. Liu, Xiaochuan; Wang, Yinsheng The Rad51 paralogs facilitate a novel DNA strand Rosenbaum, Joel C; R01ES007061 Nat Commun (2019 08 05) 31383866 2019 specific damage tolerance pathway. Bonilla, Braulio; Hengel, Sarah R; Mertz, Tony M; Herken, Benjamin W; Kazemi ... The RecQ helicase Sgs1 drives ATP-dependent Crickard, J Brooks; R01ES007061 Nucleic Acids Res (2019 30916344 2019 disruption of Rad51 filaments. Xue, Chaoyou; Wang, 05 21) Weibin; Kwon, Youngho; Sung, Patrick; Greene, Eric C Transcription shapes DNA replication initiation and Chen, Yu-Hung; R01ES025166 Nat Struct Mol Biol (2019 30598550 2019 termination in human cells. Keegan, Sarah; Kahli, 01) Malik; Tonzi, Peter; Fenyö, David; Huang, Tony T; Smith, ... Transcriptional Bypass of DNA-Protein and Ji, Shaofei; Thomforde, R01ES023350, ACS Chem Biol (2019 12 31573793 2019 DNA-Peptide Conjugates by T7 RNA Polymerase. Jenna; Rogers, Colette; R01ES025987 20) Fu, Iwen; Broyde, Suse; Tretyakova, Natalia Y Unlike the Escherichia coli counterpart, archaeal Malfatti, Matilde R01ES026243 J Biol Chem (2019 08 30) 31300556 2019 RNase HII cannot process ribose monophosphate abas Clarissa; Henneke, ... Ghislaine; Balachander, Sathya; Koh, Kyung Duk; Newnam, Ga ... Virtual Pharmacophore Screening Identifies Dash, Radha C; Ozen, P30ES002109, ChemMedChem (2019 09 31361935 2019 Small-Molecule Inhibitors of the Rev1-CT/RIR Zuleyha; McCarthy, R35ES028303 04) Protein-Prot ... Kaitlyn R; Chatterjee, Nimrat; Harris, Cynthia A; Rizzo ... Vitamin C increases DNA breaks and suppresses DNA Rubis, Blazej; Luczak, R01ES028072 Free Radic Biol Med (2019 30926564 2019 damage-independent activation of ATM by bleomycin. Michal W; Krawic, 05 20) Casey; Zhitkovich, Anatoly 5-Formylcytosine mediated DNA-protein cross-links Ji, Shaofei; Fu, Iwen; R01ES023350, Nucleic Acids Res (2018 29905846 2018 block DNA replication and induce mutations in huma Naldiga, Spandana; R01ES025987 07 27) ... Shao, Hongzhao; Basu, Ashis K; Broyde, Suse; Tretyak ... A DNA nick at Ku-blocked double-strand break ends Wang, Weibin; Daley, R01ES007061 J Biol Chem (2018 11 02) 30224356 2018 serves as an entry site for exonuclease 1 (Exo1) o ... James M; Kwon, Youngho; Xue, Xiaoyu; Krasner, Danielle S; Miller, Adam S; ... A new mitotic activity comes into focus. Saldivar, Joshua C; R01ES016486 Science (2018 01 05) 29302000 2018 Cimprich, Karlene A A quantitative PCR-based assay reveals that Chesner, Lisa N; R01ES023350 DNA Repair (Amst) (2018 29413806 2018 nucleotide excision repair plays a predominant role in t Campbell, Colin 02) ... A Simple, Rapid, and Quantitative Assay to Measure Chesner, Lisa N; R01ES023350 J Vis Exp (2018 03 05) 29553515 2018 Repair of DNA-protein Crosslinks on Plasmids Tran ... Campbell, Colin
An intrinsic S/G2 checkpoint enforced by ATR. Saldivar, Joshua C; R01ES016486 Science (2018 08 24) 30139873 2018 Hamperl, Stephan; Bocek, Michael J; Chung, Mingyu; Bass, Thomas E; Cisneros ... Arsenite Targets the RING Finger Domain of Rbx1 E3 Jiang, Ji; Tam, Lok R01ES025121 Chem Res Toxicol (2018 29658272 2018 Ubiquitin Ligase to Inhibit Proteasome-Mediated D ... Ming; Wang, 05 21) Pengcheng; Wang, Yinsheng Cisplatin-DNA adduct repair of transcribed genes is Yang, Yanyan; Adebali, P30ES010126, Proc Natl Acad Sci U S A 29735688 2018 controlled by two circadian programs in mouse ti ... Ogun; Wu, Gang; Selby, R01ES027255 (2018 05 22) Christopher P; Chiou, Yi-Ying; Rashid, Naim; Hu, ... Comparative properties and functions of type 2 and Wang, Xuefeng; Jing, R01ES027255 Cell Mol Life Sci (2018 30264181 2018 type 4 pigeon cryptochromes. Chengyu; Selby, Dec) Christopher P; Chiou, Yi-Ying; Yang, Yanyan; Wu, Wenjian; ... Configurational and Conformational Equilibria of Bamberger, Stephanie R01ES029357, Chem Res Toxicol (2018 30169026 2018 N6-(2-Deoxy-d-erythro-pentofuranosyl)-2,6-diamino-3 N; Malik, Chanchal K; T32ES007028 09 17) ... Voehler, Markus W; Brown, Summer K; Pan, Hope; Johns ... Corrigendum: 5-Formylcytosine mediated Ji, Shaofei; Fu, Iwen; R01ES025987 Nucleic Acids Res (2018 30184121 2018 DNA-protein cross-links block DNA replication and Naldiga, Spandana; 10 12) induce muta ... Shao, Hongzhao; Basu, Ashis K; Broyde, Suse; Tretyak ... Cytotoxic and mutagenic properties of alkyl Wu, Jiabin; Wang, R01ES025121 Nucleic Acids Res (2018 29514270 2018 phosphotriester lesions in Escherichia coli cells. Pengcheng; Wang, 05 04) Yinsheng Cytotoxic and mutagenic properties of minor-groove Wu, Jun; Wang, R01ES025121 J Biol Chem (2018 06 01) 29685891 2018 O2-alkylthymidine lesions in human cells. Pengcheng; Li, Lin; You, Changjun; Wang, Yinsheng Cytotoxic and mutagenic properties of Wang, Pengcheng; R01ES025121 J Biol Chem (2018 09 28) 30068548 2018 O6-alkyl-2'-deoxyguanosine lesions in Escherichia coli Wang, Yinsheng cells. DNA Damage, Mutagenesis and Cancer. Basu, Ashis K R01ES023350 Int J Mol Sci (2018 Mar 29570697 2018 23) Electron-Mediated Aminyl and Iminyl Radicals from Wen, Zhiwei; Peng, R01ES005775 Org Lett (2018 12 07) 30457873 2018 C5 Azido-Modified Pyrimidine Nucleosides Augment Jufang; Tuttle, Paloma R ... R; Ren, Yaou; Garcia, Carol; Debnath, Dipra; Rishi, ... Enhanced spontaneous DNA twisting/bending Chakraborty, Sagnik; R01ES025987 Nucleic Acids Res (2018 29267981 2018 fluctuations unveiled by fluorescence lifetime Steinbach, Peter J; Paul, 02 16) distributio ... Debamita; Mu, Hong; Broyde, Suse; Min, Jung-Hyu ... Evidence that microplastics aggravate the toxicity of Deng, Yongfeng; R01ES027981 J Hazard Mater (2018 09 29908513 2018 organophosphorus flame retardants in mice (Mus ... Zhang, Yan; Qiao, 05) Ruxia; Bonilla, Melvin M; Yang, Xiaoliang; Ren, Hongqiang; L ... Explosive mutation accumulation triggered by Hodel, Karl P; de Borja, R01ES028271 Elife (2018 02 28) 29488881 2018 heterozygous human Pol ε proofreading-deficiency is Richard; Henninger, dri ... Erin E; Campbell, Brittany B; Ungerleider, Nathan; ... Functional Analysis of Cancer-Associated DNA Barbari, Stephanie R; R01ES015869 G3 (Bethesda) (2018 03 29352080 2018 Polymerase ε Variants in Saccharomyces cerevisiae. Kane, Daniel P; Moore, 02) Elizabeth A; Shcherbakova, Polina V Genome-wide excision repair in Arabidopsis is Oztas, Onur; Selby, P30ES010126, Nat Commun (2018 04 17) 29666379 2018 coupled to transcription and reflects circadian gene e ... Christopher P; Sancar, R01ES027255 Aziz; Adebali, Ogun Histone tails decrease N7-methyl-2'-deoxyguanosine Yang, Kun; Park, R01ES023350 Proc Natl Acad Sci U S A 30429328 2018 depurination and yield DNA-protein cross-links in ... Daeyoon; Tretyakova, (2018 11 27) Natalia Y; Greenberg, Marc M Hypoxia Promotes Resistance to EGFR Inhibition in Lu, Yuhong; Liu, R01ES005775 Mol Cancer Res (2018 10) 29934325 2018 NSCLC Cells via the Histone Demethylases, LSD1 Yanfeng; Oeck, and ... Sebastian; Glazer, Peter M Identification of ATIC as a Novel Target for Liu, Xiangfei; Paila, R01ES027121 Int J Radiat Oncol Biol 29029884 2018 Chemoradiosensitization. Uma Devi; Teraoka, Phys (2018 01 01) Sharon N; Wright, Jocyndra A; Huang, Xin; Quinlan, Aa ... Identification of YTH Domain-Containing Proteins as Dai, Xiaoxia; Wang, R01ES025121, Anal Chem (2018 06 05) 29791134 2018 the Readers for N1-Methyladenosine in RNA. Tianlu; Gonzalez, T32ES018827 Gwendolyn; Wang, Yinsheng Impact of tobacco-specific nitrosamine-derived DNA Du, Hua; Leng, Jiapeng; R01ES025121 J Biol Chem (2018 07 13) 29789427 2018 adducts on the efficiency and fidelity of DNA rep ... Wang, Pengcheng; Li, Lin; Wang, Yinsheng Importance of homo-dimerization of Rao, Timsi; Longerich, R01ES007061 DNA Repair (Amst) (2018 29518739 2018 Fanconi-associated nuclease 1 in DNA flap cleavage. Simonne; Zhao, 04) Weixing; Aihara, Hideki; Sung, Patrick; Xiong, Yong In a Class of Its Own: A New Family of Coleman, Kate E; R01ES025166 Mol Cell (2018 04 05) 29625031 2018 Deubiquitinases Promotes Genome Stability. Huang, Tony T Incomplete base excision repair contributes to cell Gruber, Charley C; R35ES028303 DNA Repair (Amst) (2018 30181041 2018 death from antibiotics and other stresses. Walker, Graham C 11) Insights into the effect of minor groove interactions Koag, Myong-Chul; R01ES026676 Biochem J (2018 02 09) 29301983 2018 and metal cofactors on mutagenic replication b ... Lee, Seongmin Introduction to the Thematic Minireview Series: DNA Sung, Patrick R01ES007061 J Biol Chem (2018 07 06) 29853635 2018 double-strand break repair and pathway choice. Krebs-cycle-deficient hereditary cancer syndromes are Sulkowski, Parker L; R01ES005775 Nat Genet (2018 08) 30013182 2018 defined by defects in homologous-recombination ... Sundaram, Ranjini K; Oeck, Sebastian; Corso, Christopher D; Liu, Yanfeng; ... Lesion Sensing during Initial Binding by Yeast Mu, Hong; Zhang, R01ES025987 Chem Res Toxicol (2018 30284444 2018 XPC/Rad4: Toward Predicting Resistance to Yingkai; Geacintov, 11 19) Nucleotide ... Nicholas E; Broyde, Suse Loss of E2F7 confers resistance to poly-ADP-ribose Clements, Kristen E; R01ES026184 Nucleic Acids Res (2018 30032296 2018 polymerase (PARP) inhibitors in BRCA2-deficient c Thakar, Tanay; Nicolae, 09 28) ... Claudia M; Liang, Xinwen; Wang, Hong-Gang; Moldova ...
Mapping-free variant calling using haplotype Audano, Peter A; R01ES026243 Bioinformatics (2018 05 29186321 2018 reconstruction from k-mer frequencies. Ravishankar, 15) Shashidhar; Vannberg, Fredrik O Meiosis-specific recombinase Dmc1 is a potent Crickard, J Brooks; R01ES007061 Proc Natl Acad Sci U S A 30301803 2018 inhibitor of the Srs2 antirecombinase. Kaniecki, Kyle; Kwon, (2018 10 23) Youngho; Sung, Patrick; Greene, Eric C Molecular basis for damage recognition and Mu, Hong; Geacintov, R01ES025987 DNA Repair (Amst) (2018 30174301 2018 verification by XPC-RAD23B and TFIIH in nucleotide Nicholas E; Broyde, 11) excisi ... Suse; Yeo, Jung-Eun; Schärer, Orlando D Monoubiquitinated γ-H2AX: Abundant product and Luczak, Michal W; R01ES028072 Toxicol Appl Pharmacol 30006243 2018 specific biomarker for non-apoptotic DNA Zhitkovich, Anatoly (2018 09 15) double-stran ... Normalized Retention Time for Targeted Analysis of Cui, Yuxiang; Wang, R01ES029749 Anal Chem (2018 12 18) 30500177 2018 the DNA Adductome. Pengcheng; Yu, Yang; Yuan, Jun; Wang, Yinsheng Nucleosome positions establish an extended mutation Brown, Alexander J; R01ES028698 PLoS Genet (2018 11) 30485262 2018 signature in melanoma. Mao, Peng; Smerdon, Michael J; Wyrick, John J; Roberts, Steven A PARP10 promotes cellular proliferation and Schleicher, Emily M; R01ES026184 Nucleic Acids Res (2018 30032250 2018 tumorigenesis by alleviating replication stress. Galvan, Adri M; 09 28) Imamura-Kawasawa, Yuka; Moldovan, George-Lucian; Nicolae, ... Pol μ dGTP mismatch insertion opposite T coupled Çağlayan, Melike; R00ES026191 Nat Commun (2018 10 11) 30310068 2018 with ligation reveals promutagenic DNA repair inter ... Wilson, Samuel H
PTEN Regulates Nonhomologous End Joining By Sulkowski, Parker L; R01ES005775 Mol Cancer Res (2018 08) 29739874 2018 Epigenetic Induction of NHEJ1/XLF. Scanlon, Susan E; Oeck, Sebastian; Glazer, Peter M Regulation of Hed1 and Rad54 binding during Crickard, J Brooks; R01ES007061 EMBO J (2018 04 03) 29444896 2018 maturation of the meiosis-specific presynaptic Kaniecki, Kyle; Kwon, complex. YoungHo; Sung, Patrick; Lisby, Michael; Greene, Eric ... Rev7 dimerization is important for assembly and Rizzo, Alessandro A; P30ES002109, Proc Natl Acad Sci U S A 30111544 2018 function of the Rev1/Polζ translesion synthesis comp ... Vassel, Faye-Marie; R35ES028303 (2018 08 28) Chatterjee, Nimrat; D'Souza, Sanjay; Li, Yunfeng; Hao, ... RNA polymerase II is released from the DNA template Chiou, Yi-Ying; Hu, R01ES027255 J Biol Chem (2018 02 16) 29282293 2018 during transcription-coupled repair in mammalian ... Jinchuan; Sancar, Aziz; Selby, Christopher P Single-nucleotide resolution dynamic repair maps of Li, Wentao; Adebali, P30ES010126, Proc Natl Acad Sci U S A 29581276 2018 UV damage in Saccharomyces cerevisiae genome. Ogun; Yang, Yanyan; R01ES027255 (2018 04 10) Selby, Christopher P; Sancar, Aziz Site-specific cross-linking of proteins to DNA via a Pujari, Suresh S; Zhang, R01ES023350 Chem Commun (Camb) 29851420 2018 new bioorthogonal approach employing oxime liga ... Yi; Ji, Shaofei; (2018 Jun 14) Distefano, Mark D; Tretyakova, Natalia Y Smoking gun for a rare mutation mechanism. Goodman, Myron F R35ES028343 Nature (2018 02 08) 29420502 2018
Spontaneous self-segregation of Rad51 and Dmc1 Crickard, J Brooks; R01ES007061 J Biol Chem (2018 03 16) 29382724 2018 DNA recombinases within mixed recombinase Kaniecki, Kyle; Kwon, filaments. YoungHo; Sung, Patrick; Greene, Eric C Stochastic Endogenous Replication Stress Causes Daigh, Leighton H; Liu, R01ES016486 Cell Syst (2018 07 25) 29909278 2018 ATR-Triggered Fluctuations in CDK2 Activity that Chad; Chung, Mingyu; Dyn ... Cimprich, Karlene A; Meyer, Tobias Structural and Kinetic Studies of the Effect of Guanine Kou, Yi; Koag, R01ES026676 Biochemistry (2018 08 28) 29957995 2018 N7 Alkylation and Metal Cofactors on DNA Rep ... Myong-Chul; Lee, Seongmin Suppression of homology-dependent DNA Scanlon, Susan E; R01ES005775 Oncotarget (2018 Jan 12) 29435132 2018 double-strand break repair induces PARP inhibitor Hegan, Denise C; sensitivity ... Sulkowski, Parker L; Glazer, Peter M Synergistic effects of H3 and H4 nucleosome tails on Cai, Yuqin; Fu, Iwen; R01ES025987 DNA Repair (Amst) (2018 29631253 2018 structure and dynamics of a lesion-containing D ... Geacintov, Nicholas E; 05) Zhang, Yingkai; Broyde, Suse The COP9 signalosome inhibits Cullin-RING E3 Suisse, Annabelle; R01ES025166 Fly (Austin) (2018) 29355077 2018 ubiquitin ligases independently of its deneddylase acti Békés, Miklós; Huang, ... Tony T; Treisman, Jessica E The hypoxic tumor microenvironment in vivo selects Kim, Hoon; Lin, Qun; R01ES005775 Breast Cancer Res (2018 29510720 2018 the cancer stem cell fate of breast cancer cells. Glazer, Peter M; Yun, 03 06) Zhong The long-range interaction map of ribosomal DNA Yu, Shoukai; Lemos, R01ES027981 PLoS Genet (2018 03) 29570716 2018 arrays. Bernardo Toxicological Antagonism among Welding Fume Krawic, Casey; R01ES028072 Chem Res Toxicol (2018 30362728 2018 Metals: Inactivation of Soluble Cr(VI) by Iron. Zhitkovich, Anatoly 11 19) Translesion polymerase kappa-dependent DNA Tonzi, Peter; Yin, R01ES025166 Elife (2018 11 13) 30422114 2018 synthesis underlies replication fork recovery. Yandong; Lee, Chelsea Wei Ting; Rothenberg, Eli; Huang, Tony T Urinary DNA adductomics - A novel approach for Cooke, Marcus S; Hu, R01ES030557 Environ Int (2018 12) 30392940 2018 exposomics. Chiung-Wen; Chang, Yuan-Jhe; Chao, Mu-Rong What is the potential of nanolock- and Gu, Li-Qun; Gates, Kent R01ES021007 Expert Rev Mol Diagn 29171309 2018 nanocross-nanopore technology in cancer diagnosis? S; Wang, Michael X; Li, (2018 02) Guangfu 2-Hydroxyglutarate produced by neomorphic IDH Sulkowski, Parker L; R01ES005775 Sci Transl Med (2017 02 28148839 2017 mutations suppresses homologous recombination and Corso, Christopher D; 01) indu ... Robinson, Nathaniel D; Scanlon, Susan E; Purshouse, ... A novel role of the Dna2 translocase function in DNA Miller, Adam S; Daley, R01ES007061 Genes Dev (2017 03 01) 28336516 2017 break resection. James M; Pham, Nhung Tuyet; Niu, Hengyao; Xue, Xiaoyu; Ira, Grzegorz; S ... A parametric model to estimate the proportion from Yu, Chang; Zelterman, R01ES005775 Comput Stat Data Anal 28827889 2017 true null using a distribution for p-values. Daniel (2017 Oct) A role for the base excision repair enzyme NEIL3 in Yang, Zhiyu; Nejad, R01ES021007, DNA Repair (Amst) (2017 28262582 2017 replication-dependent repair of interstrand DNA ... Maryam Imani; Varela, T32ES018827 04) Jacqueline Gamboa; Price, Nathan E; Wang, Yinsheng; G ... Abasic and oxidized ribonucleotides embedded in Malfatti, Matilde R01ES026243 Nucleic Acids Res (2017 28977421 2017 DNA are processed by human APE1 and not by RNase Clarissa; Balachander, Nov 02) H2. Sathya; Antoniali, Giulia; Koh, Kyung Duk; Saint-Pierre ... Anti-tumor Activity of miniPEG-γ-Modified PNAs to Gupta, Anisha; Quijano, R01ES005775 Mol Ther Nucleic Acids 29246289 2017 Inhibit MicroRNA-210 for Cancer Therapy. Elias; Liu, Yanfeng; (2017 Dec 15) Bahal, Raman; Scanlon, Susan E; Song, Eric; Hsieh ... ATM, radiation, and the risk of second primary breast Bernstein, Jonine L; R01ES027121 Int J Radiat Biol (2017 10) 28627265 2017 cancer. WECARE Study Collaborative Group; Concannon, Patrick BRCA1-BARD1 promotes RAD51-mediated Zhao, Weixing; R01ES007061 Nature (2017 10 19) 28976962 2017 homologous DNA pairing. Steinfeld, Justin B; Liang, Fengshan; Chen, Xiaoyong; Maranon, David G; Jian Ma, ... Cellular Repair of DNA-DNA Cross-Links Induced by Chesner, Lisa N; R01ES023350 Int J Mol Sci (2017 May 28524082 2017 1,2,3,4-Diepoxybutane. Degner, Amanda; 18) Sangaraju, Dewakar; Yomtoubian, Shira; Wickramaratne, Susith; ... Chemical Biology of N5-Substituted Pujari, Suresh S; R01ES023350 Chem Res Toxicol (2017 27959490 2017 Formamidopyrimidine DNA Adducts. Tretyakova, Natalia 01 17) Comprehensive Analysis of Hypermutation in Human Campbell, Brittany B; R01ES028271 Cell (2017 Nov 16) 29056344 2017 Cancer. Light, Nicholas; Fabrizio, David; Zatzman, Matthew; Fuligni, Fabio; de Bo ... Controlling the Graphene-Bio Interface: Dispersions in Pattammattel, Ajith; R01ES023350 Langmuir (2017 12 12) 29144756 2017 Animal Sera for Enhanced Stability and Reduce ... Pande, Paritosh; Kuttappan, Deepa; Puglia, Megan; Basu, Ashis K; Amalaradj ... Cryo-EM structures of human RAD51 recombinase Xu, Jingfei; Zhao, R01ES007061 Nat Struct Mol Biol (2017 27941862 2017 filaments during catalysis of DNA-strand exchange. Lingyun; Xu, 01) Yuanyuan; Zhao, Weixing; Sung, Patrick; Wang, Hong-Wei Cytotoxic and Mutagenic Properties of C3'-Epimeric Wang, Pengcheng; R01ES025121, Biochemistry (2017 07 25) 28650656 2017 Lesions of 2'-Deoxyribonucleosides in Escherichia ... Amato, Nicholas J; T32ES018827 Wang, Yinsheng Detection of the Excised, Damage-containing Song, Jimyeong; Kemp, R01ES027255 Photochem Photobiol 27634428 2017 Oligonucleotide Products of Nucleotide Excision Michael G; Choi, (2017 01) Repair i ... Jun-Hyuk Dissociation of Rad51 Presynaptic Complexes and Kaniecki, Kyle; De R01ES007061 Cell Rep (2017 Dec 12) 29241544 2017 Heteroduplex DNA Joints by Tandem Assemblies of Tullio, Luisina; Gibb, Srs2 ... Bryan; Kwon, Youngho; Sung, Patrick; Greene, Eric C Dynamic maps of UV damage formation and repair for Hu, Jinchuan; Adebali, P30ES010126, Proc Natl Acad Sci U S A 28607063 2017 the human genome. Ogun; Adar, Sheera; R01ES027255 (2017 06 27) Sancar, Aziz Enhancement of BLM-DNA2-Mediated Long-Range Daley, James M; R01ES007061 Cell Rep (2017 Oct 10) 29020620 2017 DNA End Resection by CtIP. Jimenez-Sainz, Judit; Wang, Weibin; Miller, Adam S; Xue, Xiaoyu; Nguyen, Kevin ... Forging Ahead through Darkness: PCNA, Still the Choe, Katherine N; R01ES026184 Mol Cell (2017 Feb 02) 28157503 2017 Principal Conductor at the Replication Fork. Moldovan, George-Lucian Genome-wide transcription-coupled repair in Adebali, Ogun; Chiou, R01ES027255 Proc Natl Acad Sci U S A 28167766 2017 Escherichia coli is mediated by the Mfd translocase. Yi-Ying; Hu, Jinchuan; (2017 03 14) Sancar, Aziz; Selby, Christopher P Human DNA polymerase η accommodates RNA for Su, Yan; Egli, Martin; R01ES010546, J Biol Chem (2017 11 03) 28972162 2017 strand extension. Guengerich, F Peter R01ES026955 Human genome-wide repair map of DNA damage Li, Wentao; Hu, P30ES010126, Proc Natl Acad Sci U S A 28607059 2017 caused by the cigarette smoke carcinogen Jinchuan; Adebali, R01ES027255 (2017 06 27) benzo[a]pyrene. Ogun; Adar, Sheera; Yang, Yanyan; Chiou, Yi-Ying; Sancar, ... Human RAD52 interactions with replication protein A Ma, Chu Jian; Kwon, R01ES007061 J Biol Chem (2017 07 14) 28551686 2017 and the RAD51 presynaptic complex. Youngho; Sung, Patrick; Greene, Eric C Liquid Chromatography-Tandem Mass Spectrometry Leng, Jiapeng; Wang, R01ES025121 Anal Chem (2017 09 05) 28749651 2017 for the Quantification of Tobacco-Specific Nitrosamin Yinsheng ... Mass Spectrometry Based Proteomics Study of Ming, Xun; Groehler R01ES023350 Chem Res Toxicol (2017 28282121 2017 Cisplatin-Induced DNA-Protein Cross-Linking in 4th, Arnold; 04 17) Human Fib ... Michaelson-Richie, Erin D; Villalta, Peter W; Campbell, Colin; ... Mass Spectrometry-Based Tools to Characterize Groehler 4th, Arnold; R01ES023350 Basic Clin Pharmacol 28032943 2017 DNA-Protein Cross-Linking by Bis-Electrophiles. Degner, Amanda; Toxicol (2017 Sep) Tretyakova, Natalia Y Mechanism of DNA alkylation-induced transcriptional Xu, Liang; Wang, Wei; R01ES025121 Proc Natl Acad Sci U S A 28784758 2017 stalling, lesion bypass, and mutagenesis. Wu, Jiabin; Shin, Ji (2017 08 22) Hyun; Wang, Pengcheng; Unarta, Ilona Christy; Chong ... Mfd Protein and Transcription-Repair Coupling in Selby, Christopher P R01ES027255 Photochem Photobiol 27864884 2017 Escherichia coli. (2017 01) Mfd translocase is necessary and sufficient for Adebali, Ogun; Sancar, R01ES027255 J Biol Chem (2017 11 10) 28986449 2017 transcription-coupled repair in Escherichia coli. Aziz; Selby, Christopher P Molecular mechanisms and genomic maps of DNA Hu, Jinchuan; Selby, P30ES010126, J Biol Chem (2017 09 22) 28798238 2017 excision repair in Escherichia coli and humans. Christopher P; Adar, R01ES027255 Sheera; Adebali, Ogun; Sancar, Aziz Mutagenicity of a Model DNA-Peptide Cross-Link in Pande, Paritosh; Ji, R01ES023350 Chem Res Toxicol (2017 27951635 2017 Human Cells: Roles of Translesion Synthesis DNA Po Shaofei; Mukherjee, Feb 20) ... Shivam; Schärer, Orlando D; Tretyakova, Natalia Y; Bas ... Nanoarmoring: strategies for preparation of Zore, Omkar V; Pande, R01ES023350 RSC Adv (2017) 29403641 2017 multi-catalytic enzyme polymer conjugates and Paritosh; Okifo, enhancemen ... Oghenenyerovwo; Basu, Ashis K; Kasi, Rajeswari M; Kumar, ... Nickel induces transcriptional down-regulation of Scanlon, Susan E; R01ES005775 Carcinogenesis (2017 06 28472268 2017 DNA repair pathways in tumorigenic and non-tumorig Scanlon, Christine D; 01) ... Hegan, Denise C; Sulkowski, Parker L; Glazer, Peter M Nucleosome Histone Tail Conformation and Fu, Iwen; Cai, Yuqin; R01ES025987 Biochemistry (2017 04 11) 28304160 2017 Dynamics: Impacts of Lysine Acetylation and a Geacintov, Nicholas E; Nearby Minor ... Zhang, Yingkai; Broyde, Suse Nucleosome-like, Single-stranded DNA Adkins, Nicholas L; P30ES025128, J Biol Chem (2017 Mar 28202543 2017 (ssDNA)-Histone Octamer Complexes and the Swygert, Sarah G; Kaur, R01ES007061 31) Implication for DNA D ... Parminder; Niu, Hengyao; Grigoryev, Sergei A; Sung, ... Nucleotide Excision Repair Lesion-Recognition Mu, Hong; Geacintov, R01ES025987 Chem Res Toxicol (2017 28460163 2017 Protein Rad4 Captures a Pre-Flipped Partner Base in a Nicholas E; Min, 06 19) ... Jung-Hyun; Zhang, Yingkai; Broyde, Suse Nucleotide selectivity defect and mutator phenotype Mertz, T M; R01ES015869 Oncogene (2017 Aug) 28368425 2017 conferred by a colon cancer-associated DNA polym ... Baranovskiy, A G; Wang, J; Tahirov, T H; Shcherbakova, P V PARPi focus the spotlight on replication fork Schlacher, Katharina R01ES029680 Nat Cell Biol (2017 Oct 29087384 2017 protection in cancer. 31) Plasticity of the Mre11-Rad50-Xrs2-Sae2 nuclease Wang, Weibin; Daley, R01ES007061 Genes Dev (2017 12 01) 29321177 2017 ensemble in the processing of DNA-bound obstacles. James M; Kwon, Youngho; Krasner, Danielle S; Sung, Patrick PostExcision Events in Human Nucleotide Excision Kemp, Michael G; Hu, R01ES027255 Photochem Photobiol 27645806 2017 Repair. Jinchuan (2017 01) Repair-Resistant DNA Lesions. Geacintov, Nicholas E; R01ES025987 Chem Res Toxicol (2017 28750166 2017 Broyde, Suse 08 21) Replicative DNA polymerase defects in human Barbari, Stephanie R; R01ES015869 DNA Repair (Amst) (2017 28687338 2017 cancers: Consequences, mechanisms, and implications Shcherbakova, Polina V 08) for ... Reversible DNA-Protein Cross-Linking at Epigenetic Ji, Shaofei; Shao, R01ES023350 Angew Chem Int Ed Engl 28898504 2017 DNA Marks. Hongzhao; Han, (2017 11 06) Qiyuan; Seiler, Christopher L; Tretyakova, Natalia Y Ribosomal DNA copy number amplification and loss Wang, Meng; Lemos, R01ES027981 PLoS Genet (2017 Sep) 28880866 2017 in human cancers is linked to tumor genetic context ... Bernardo
Role of DNA polymerase β oxidized nucleotide Çaglayan, Melike; R00ES026191 J Radiat Res (2017 Sep 01) 28992331 2017 insertion in DNA ligation failure. Wilson, Samuel H Role of the Pif1-PCNA Complex in Pol δ-Dependent Buzovetsky, Olga; R01ES007061 Cell Rep (2017 Nov 14) 29141206 2017 Strand Displacement DNA Synthesis and Kwon, Youngho; Pham, Break-Induced ... Nhung Tuyet; Kim, Claire; Ira, Grzegorz; Sung, Patrick; ... SENP8 limits aberrant neddylation of NEDD8 Coleman, Kate E; R01ES025166 Elife (2017 05 05) 28475037 2017 pathway components to promote cullin-RING Békés, Miklós; ubiquitin ligas ... Chapman, Jessica R; Crist, Sarah B; Jones, Mathew Jk; Ueberheid ... Sequence imperfections and base triplet recognition by Lee, Ja Yil; Steinfeld, R01ES007061 J Biol Chem (2017 06 30) 28476890 2017 the Rad51/RecA family of recombinases. Justin B; Qi, Zhi; Kwon, YoungHo; Sung, Patrick; Greene, Eric C Sequence-Specific Covalent Capture Coupled with Nejad, Maryam Imani; R01ES021007 Chembiochem (2017 07 28422400 2017 High-Contrast Nanopore Detection of a Shi, Ruicheng; Zhang, 18) Disease-Derive ... Xinyue; Gu, Li-Qun; Gates, Kent S The Cartography of UV-induced DNA Damage Hu, Jinchuan; Adar, R01ES027255 Photochem Photobiol 27861959 2017 Formation and DNA Repair. Sheera (2017 01) The essential kinase ATR: ensuring faithful Saldivar, Joshua C; R01ES016486 Nat Rev Mol Cell Biol 28811666 2017 duplication of a challenging genome. Cortez, David; (2017 10) Cimprich, Karlene A The Nonbulky DNA Lesions Spiroiminodihydantoin Kolbanovskiy, Marina; R01ES025987 Biochemistry (2017 06 20) 28514164 2017 and 5-Guanidinohydantoin Significantly Block Human Chowdhury, Moinuddin RN ... A; Nadkarni, Aditi; Broyde, Suse; Geacintov, Nichola ... Translesion Synthesis of 2'-Deoxyguanosine Lesions Basu, Ashis K; Pande, R01ES021762, Chem Res Toxicol (2017 27760288 2017 by Eukaryotic DNA Polymerases. Paritosh; Bose, Arindam R01ES023350 01 17) Ultrathin Graphene-Protein Supercapacitors for Mosa, Islam M; R01ES023350 Adv Energy Mater (2017 29104523 2017 Miniaturized Bioelectronics. Pattammattel, Ajith; Sep 06) Kadimisetty, Karteek; Pande, Paritosh; El-Kady, Maher F; Bi ...
Yeast DNA polymerase ζ maintains consistent activity Kochenova, Olga V; R01ES015869 Nucleic Acids Res (2017 28180291 2017 and mutagenicity across a wide range of physiol ... Bezalel-Buch, Rachel; 02 17) Tran, Phong; Makarova, Alena V; Chabes, Andrei; Burger ... Yeast Srs2 Helicase Promotes Redistribution of De Tullio, Luisina; R01ES007061 Cell Rep (2017 Oct 17) 29045827 2017 Single-Stranded DNA-Bound RPA and Rad52 in Kaniecki, Kyle; Kwon, Homologous ... Youngho; Crickard, J Brooks; Sung, Patrick; Greene, ... Bypass of DNA-Protein Cross-links Conjugated to the Wickramaratne, Susith; R01ES010546, J Biol Chem (2016 Nov 27621316 2016 7-Deazaguanine Position of DNA by Translesion Sy ... Ji, Shaofei; Mukherjee, R01ES023350, 04) Shivam; Su, Yan; R01ES025987 Pence, Matthew G; Lior-Hoffmann ... Cisplatin DNA damage and repair maps of the human Hu, Jinchuan; Lieb, P30ES010126, Proc Natl Acad Sci U S A 27688757 2016 genome at single-nucleotide resolution. Jason D; Sancar, Aziz; R01ES027255 (2016 10 11) Adar, Sheera Comparative Error-Free and Error-Prone Translesion Bose, Arindam; R01ES023350 Chem Res Toxicol (2016 27082015 2016 Synthesis of N(2)-2'-Deoxyguanosine Adducts Forme Surugihalli, Chaitra; 05 16) ... Pande, Paritosh; Champeil, Elise; Basu, Ashis K Covalent DNA-Protein Cross-Linking by Groehler 4th, Arnold; R01ES023350 Chem Res Toxicol (2016 26692166 2016 Phosphoramide Mustard and Nornitrogen Mustard in Villalta, Peter W; Feb 15) Human Cells. Campbell, Colin; Tretyakova, Natalia Differential regulation of the anti-crossover and Xue, Xiaoyu; Papusha, R01ES007061 Genes Dev (2016 03 15) 26966246 2016 replication fork regression activities of Mph1 by ... Alma; Choi, Koyi; Bonner, Jacob N; Kumar, Sandeep; Niu, Hengyao; Kaur, ... Directed evolution using dCas9-targeted somatic Hess, Gaelen T; Frésard, R01ES016486 Nat Methods (2016 Dec) 27798611 2016 hypermutation in mammalian cells. Laure; Han, Kyuho; Lee, Cameron H; Li, Amy; Cimprich, Karlene A; Mont ... Effective molarity in a nucleic acid-controlled reaction. Catalano, Michael J; R01ES021007 Bioorg Med Chem Lett 27117430 2016 Price, Nathan E; Gates, (2016 06 01) Kent S Enrichment of Cdk1-cyclins at DNA double-strand Chen, Xuefeng; Niu, R01ES007061 Nucleic Acids Res (2016 26801641 2016 breaks stimulates Fun30 phosphorylation and DNA Hengyao; Yu, Yang; Apr 07) end ... Wang, Jingjing; Zhu, Shuangyi; Zhou, Jianjie; Papusha, ... How SUMOylation Fine-Tunes the Fanconi Anemia Coleman, Kate E; R01ES025166 Front Genet (2016) 27148358 2016 DNA Repair Pathway. Huang, Tony T HUWE1 comes to the rescue at stalled replication Coleman, Kate E; R01ES025166 EMBO Rep (2016 06) 27146074 2016 forks. Huang, Tony T HUWE1 interacts with PCNA to alleviate replication Choe, Katherine N; R01ES026184 EMBO Rep (2016 06) 27146073 2016 stress. Nicolae, Claudia M; Constantin, Daniel; Imamura Kawasawa, Yuka; Delgado-Diaz, ... In Vitro Lesion Bypass Studies of Williams, Nicole L; R01ES025121 Chem Res Toxicol (2016 27002924 2016 O(4)-Alkylthymidines with Human DNA Polymerase Wang, Pengcheng; Wu, Apr 18) η. Jiabin; Wang, Yinsheng Mass Spectrometry-Based Quantitative Strategies for You, Changjun; Wang, R01ES025121 Acc Chem Res (2016 Feb 26758048 2016 Assessing the Biological Consequences and Repair ... Yinsheng 16) Mek1 Down Regulates Rad51 Activity during Yeast Callender, Tracy L; R01ES007061 PLoS Genet (2016 Aug) 27483004 2016 Meiosis by Phosphorylation of Hed1. Laureau, Raphaelle; Wan, Lihong; Chen, Xiangyu; Sandhu, Rima; Laljee, Saif ... miR-155 Overexpression Promotes Genomic Czochor, Jennifer R; R01ES005775 Mol Cancer Res (2016 26850462 2016 Instability by Reducing High-fidelity Polymerase Sulkowski, Parker; Apr) Delta Expre ... Glazer, Peter M PARP10 deficiency manifests by severe Shahrour, Maher Awni; R01ES026184 Neurogenetics (2016 10) 27624574 2016 developmental delay and DNA repair defect. Nicolae, Claudia M; Edvardson, Simon; Ashhab, Motee; Galvan, Adri M; Cons ... Patterns of growth and tract formation during the early Lovick, Jennifer K; R01ES029357 Dev Neurobiol (2016 Apr) 26178322 2016 development of secondary lineages in the Dro ... Kong, Angel; Omoto, Jaison J; Ngo, Kathy T; Younossi-Hartenstein, Amelia; H ... Promotion of RAD51-Mediated Homologous DNA Liang, Fengshan; R01ES007061 Cell Rep (2016 06 07) 27239033 2016 Pairing by the RAD51AP1-UAF1 Complex. Longerich, Simonne; Miller, Adam S; Tang, Caroline; Buzovetsky, Olga; Xiong, ... Recognition of Lys48-Linked Di-ubiquitin and Békés, Miklós; van der R01ES025166 Mol Cell (2016 05 19) 27203180 2016 Deubiquitinating Activities of the SARS Coronavirus Heden van Noort, Pap ... Gerbrand J; Ekkebus, Reggy; Ovaa, Huib; Huang, Tony T; ... Replicative Bypass of O2-Alkylthymidine Lesions in Williams, Nicole L; R01ES025121 Chem Res Toxicol (2016 27611246 2016 Vitro. Wang, Pengcheng; 10 17) Wang, Yinsheng Roles of Aag, Alkbh2, and Alkbh3 in the Repair of You, Changjun; Wang, R01ES025121, ACS Chem Biol (2016 05 26930515 2016 Carboxymethylated and Ethylated Thymidine Lesions. Pengcheng; Nay, T32ES018827 20) Stephanie L; Wang, Jianshuang; Dai, Xiaoxia; O'Connor, Ti ... Simple, High-Yield Syntheses of DNA Duplexes Gamboa Varela, R01ES021007 Curr Protoc Nucleic Acid 27248783 2016 Containing Interstrand DNA-DNA Cross-Links Jacqueline; Gates, Kent Chem (2016 06 01) Between an N ... S Tel1 and Rif2 Regulate MRX Functions in Cassani, Corinne; R01ES007061 PLoS Biol (2016 Feb) 26901759 2016 End-Tethering and Repair of DNA Double-Strand Gobbini, Elisa; Wang, Breaks. Weibin; Niu, Hengyao; Clerici, Michela; Sung, Patrick; ... Translesion synthesis of O4-alkylthymidine lesions in Wu, Jun; Li, Lin; Wang, R01ES025121 Nucleic Acids Res (2016 27466394 2016 human cells. Pengcheng; You, Nov 02) Changjun; Williams, Nicole L; Wang, Yinsheng Yeast DNA polymerase ζ maintains consistent activity Kochenova, Olga V; R01ES015869 Nucleic Acids Res (2016 27903904 2016 and mutagenicity across a wide range of physiol ... Bezalel-Buch, Rachel; Nov 29) Tran, Phong; Makarova, Alena V; Chabes, Andrei; Burger ... A simple, high-yield synthesis of DNA duplexes Gamboa Varela, R01ES021007 Angew Chem Int Ed Engl 25967397 2015 containing a covalent, thermally cleavable interstran ... Jacqueline; Gates, Kent (2015 Jun 22) S Characterization of Interstrand DNA-DNA Yang, Zhiyu; Price, R01ES021007 Biochemistry (2015 Jul 14) 26103998 2015 Cross-Links Derived from Abasic Sites Using Nathan E; Johnson, Bacteriophage ϕ2 ... Kevin M; Gates, Kent S Characterization of Interstrand DNA-DNA Zhang, Xinyue; Price, R01ES021007 ACS Nano (2015 Dec 22) 26563913 2015 Cross-Links Using the α-Hemolysin Protein Nanopore. Nathan E; Fang, Xi; Yang, Zhiyu; Gu, Li-Qun; Gates, Kent S Chemical and structural characterization of interstrand Price, Nathan E; R01ES021007 Nucleic Acids Res (2015 25779045 2015 cross-links formed between abasic sites and ... Catalano, Michael J; Apr 20) Liu, Shuo; Wang, Yinsheng; Gates, Kent S
Chemical structure and properties of interstrand Catalano, Michael J; R01ES021007 J Am Chem Soc (2015 25710271 2015 cross-links formed by reaction of guanine residues ... Liu, Shuo; Andersen, Mar 25) Nisana; Yang, Zhiyu; Johnson, Kevin M; Price, Nathan ... Colon cancer-associated mutator DNA polymerase δ Mertz, Tony M; R01ES015869 Proc Natl Acad Sci U S A 25827231 2015 variant causes expansion of dNTP pools increasing i ... Sharma, Sushma; (2015 May 12) Chabes, Andrei; Shcherbakova, Polina V Cytotoxic and mutagenic properties of Wang, Pengcheng; R01ES025121 Nucleic Acids Res (2015 26400162 2015 O4-alkylthymidine lesions in Escherichia coli cells. Amato, Nicholas J; Dec 15) Zhai, Qianqian; Wang, Yinsheng DNA polymerase ζ-dependent lesion bypass in Kochenova, Olga V; R01ES015869 PLoS Genet (2015 Mar) 25826305 2015 Saccharomyces cerevisiae is accompanied by Daee, Danielle L; error-prone c ... Mertz, Tony M; Shcherbakova, Polina V DNA replication stress underlies renal phenotypes in Slaats, Gisela G; R01ES016486 J Clin Invest (2015 Sep) 26301811 2015 CEP290-associated Joubert syndrome. Saldivar, Joshua C; Bacal, Julien; Zeman, Michelle K; Kile, Andrew C; Hynes, ... DNA sequence alignment by microhomology sampling Qi, Zhi; Redding, Sy; R01ES007061 Cell (2015 Feb 26) 25684365 2015 during homologous recombination. Lee, Ja Yil; Gibb, Bryan; Kwon, YoungHo; Niu, Hengyao; Gaines, William ... DNA-Protein Cross-Links: Formation, Structural Tretyakova, Natalia Y; R01ES023350 Acc Chem Res (2015 Jun 26032357 2015 Identities, and Biological Outcomes. Groehler 4th, Arnold; Ji, 16) Shaofei Error-prone translesion synthesis past DNA-peptide Wickramaratne, Susith; R01ES023350 J Biol Chem (2015 Jan 09) 25391658 2015 cross-links conjugated to the major groove of DNA ... Boldry, Emily J; Buehler, Charles; Wang, Yen-Chih; Distefano, Mark D; Tr ... Functions and regulation of the multitasking FANCM Xue, Xiaoyu; Sung, R01ES007061 Genes Dev (2015 Sep 01) 26341555 2015 family of DNA motor proteins. Patrick; Zhao, Xiaolan HLTF's Ancient HIRAN Domain Binds 3' DNA Ends Kile, Andrew C; R01ES016486 Mol Cell (2015 Jun 18) 26051180 2015 to Drive Replication Fork Reversal. Chavez, Diana A; Bacal, Julien; Eldirany, Sherif; Korzhnev, Dmitry M; Bezsonova ... LKB1 preserves genome integrity by stimulating Gupta, Romi; Liu, Alex R01ES005775 Nucleic Acids Res (2015 25488815 2015 BRCA1 expression. Y; Glazer, Peter M; Jan) Wajapeyee, Narendra Markov counting models for correlated binary Crawford, Forrest W; R01ES005775 Biostatistics (2015 Jul) 25792624 2015 responses. Zelterman, Daniel Mass spectrometry for the assessment of the Liu, Shuo; Wang, R01ES021007 Chem Soc Rev (2015 Nov 26204249 2015 occurrence and biological consequences of DNA Yinsheng 7) adducts. Mechanism of action studies of lomaiviticin A and the Colis, Laureen C; R01ES005775 J Am Chem Soc (2015 25849366 2015 monomeric lomaiviticin aglycon. Selective and ... Hegan, Denise C; May 6) Kaneko, Miho; Glazer, Peter M; Herzon, Seth B MicroRNA silencing for cancer therapy targeted to the Cheng, Christopher J; R01ES005775 Nature (2015 Feb 05) 25409146 2015 tumour microenvironment. Bahal, Raman; Babar, Imran A; Pincus, Zachary; Barrera, Francisco; Liu, ... Mimicking Ribosomal Unfolding of RNA Pseudoknot Zhang, Xinyue; Xu, R01ES021007 J Am Chem Soc (2015 26595106 2015 in a Protein Channel. Xiaojun; Yang, Zhiyu; Dec 23) Burcke, Andrew J; Gates, Kent S; Chen, Shi-Jie; Gu, ... Multifaceted control of DNA repair pathways by the Scanlon, Susan E; R01ES005775 DNA Repair (Amst) (2015 25956861 2015 hypoxic tumor microenvironment. Glazer, Peter M Aug) Origin and development of neuropil glia of the Omoto, Jaison Jiro; R01ES029357 Dev Biol (2015 Aug 15) 25779704 2015 Drosophila larval and adult brain: Two distinct glial ... Yogi, Puja; Hartenstein, Volker Promotion of BRCA2-Dependent Homologous Zhao, Weixing; R01ES007061 Mol Cell (2015 Jul 16) 26145171 2015 Recombination by DSS1 via RPA Targeting and DNA Vaithiyalingam, Mimicry. Sivaraja; San Filippo, Joseph; Maranon, David G; Jimenez-Sainz, ... Promotion of presynaptic filament assembly by the Gaines, William A; R01ES007061 Nat Commun (2015) 26215801 2015 ensemble of S. cerevisiae Rad51 paralogues with Ra ... Godin, Stephen K; Kabbinavar, Faiz F; Rao, Timsi; VanDemark, Andrew P; Sung, ... Quantitative measurement of transcriptional inhibition You, Changjun; Wang, R01ES025121 Nat Protoc (2015 Sep) 26292071 2015 and mutagenesis induced by site-specifically ... Yinsheng Selective modulation of the functions of a conserved Xue, Xiaoyu; Choi, R01ES007061 Genes Dev (2015 05 15) 25956905 2015 DNA motor by a histone fold complex. Koyi; Bonner, Jacob N; Szakal, Barnabas; Chen, Yu-Hung; Papusha, Alma; Saro ... Significance of ligand interactions involving Zhao, Weixing; Sung, R01ES007061 Nucleic Acids Res (2015 25820426 2015 Hop2-Mnd1 and the RAD51 and DMC1 recombinases Patrick Apr 30) in homol ... Synthesis of DNA Oligodeoxynucleotides Containing Wickramaratne, Susith; R01ES023350 Curr Protoc Nucleic Acid 26344227 2015 Site-Specific 1,3-Butadiene-Deoxyadenosine Lesions Seiler, Christopher L; Chem (2015 Jun 03) ... Tretyakova, Natalia Y Synthetic viability genomic screening defines Sae2 Puddu, Fabio; R01ES007061 EMBO J (2015 Jun 03) 25899817 2015 function in DNA repair. Oelschlaegel, Tobias; Guerini, Ilaria; Geisler, Nicola J; Niu, Hengyao; Herzog, ... Tumor suppressor p53 stole the AKT in hypoxia. Yun, Zhong; Glazer, R01ES005775 J Clin Invest (2015 Jun) 25961449 2015 Peter M A common cancer-associated DNA polymerase ε Kane, Daniel P; R01ES015869 Cancer Res (2014 Apr 1) 24525744 2014 mutation causes an exceptionally strong mutator Shcherbakova, Polina V phenotyp ... Avoidance of ribonucleotide-induced mutations by Potenski, Catherine J; R01ES007061 Nature (2014 Jul 10) 24896181 2014 RNase H2 and Srs2-Exo1 mechanisms. Niu, Hengyao; Sung, Patrick; Klein, Hannah L Causes and consequences of replication stress. Zeman, Michelle K; R01ES016486 Nat Cell Biol (2014 Jan) 24366029 2014 Cimprich, Karlene A Concentration-dependent exchange of replication Gibb, Bryan; Ye, Ling R01ES007061 PLoS One (2014) 24498402 2014 protein A on single-stranded DNA revealed by single- F; Gergoudis, Stephanie ... C; Kwon, YoungHo; Niu, Hengyao; Sung, Patrick; G ... Covalent adduct formation between the Melton, Douglas; Lewis, R01ES021007 Chem Res Toxicol (2014 25405892 2014 antihypertensive drug hydralazine and abasic sites in Calvin D; Price, Nathan Dec 15) double- ... E; Gates, Kent S DNA damage-specific deubiquitination regulates Zeman, Michelle K; Lin, R01ES016486 J Cell Biol (2014 Jul 21) 25023518 2014 Rad18 functions to suppress mutagenesis. Jia-Ren; Freire, Raimundo; Cimprich, Karlene A DNA polymerases ζ and Rev1 mediate error-prone Northam, Matthew R; R01ES015869 Nucleic Acids Res (2014 24049079 2014 bypass of non-B DNA structures. Moore, Elizabeth A; Jan) Mertz, Tony M; Binz, Sara K; Stith, Carrie M; Stepchenk ... Down-regulation of Rad51 activity during meiosis in Liu, Yan; Gaines, R01ES007061 PLoS Genet (2014 Jan) 24465215 2014 yeast prevents competition with Dmc1 for repair ... William A; Callender, Tracy; Busygina, Valeria; Oke, Ashwini; Sung, Patrick; ... Hypoxic stress facilitates acute activation and chronic Scanlon, Susan E; R01ES005775 Mol Cancer Res (2014 Jul) 24688021 2014 downregulation of fanconi anemia proteins. Glazer, Peter M Interstrand DNA-DNA cross-link formation between Price, Nathan E; R01ES021007 J Am Chem Soc (2014 24506784 2014 adenine residues and abasic sites in duplex DNA. Johnson, Kevin M; Mar 5) Wang, Jin; Fekry, Mostafa I; Wang, Yinsheng; Gates, Kent S Mechanistic insights into the role of Hop2-Mnd1 in Zhao, Weixing; Saro, R01ES007061 Nucleic Acids Res (2014 24150939 2014 meiotic homologous DNA pairing. Dorina; Hammel, Jan) Michal; Kwon, Youngho; Xu, Yuanyuan; Rambo, Robert P; Wil ... Protein dynamics during presynaptic-complex Gibb, Bryan; Ye, Ling R01ES007061 Nat Struct Mol Biol (2014 25195049 2014 assembly on individual single-stranded DNA F; Kwon, YoungHo; Oct) molecules. Niu, Hengyao; Sung, Patrick; Greene, Eric C Replicative bypass of abasic site in Escherichia coli Weerasooriya, Savithri; R01ES021762, PLoS One (2014) 25226389 2014 and human cells: similarities and differences. Jasti, Vijay P; Basu, R01ES023350 Ashis K Restriction of replication fork regression activities by a Xue, Xiaoyu; Choi, R01ES007061 Mol Cell (2014 11 06) 25439736 2014 conserved SMC complex. Koyi; Bonner, Jacob N; Chiba, Tamara; Kwon, Youngho; Xu, Yuanyuan; Sanchez, ... Silencing of the DNA mismatch repair gene MLH1 Lu, Yuhong; R01ES005775 Cell Rep (2014 Jul 24) 25043185 2014 induced by hypoxic stress in a pathway dependent on t Wajapeyee, Narendra; ... Turker, Mitchell S; Glazer, Peter M Syntheses and characterizations of the in vivo Zhai, Qianqian; Wang, R01ES025121 Nucleic Acids Res (2014) 25120272 2014 replicative bypass and mutagenic properties of the mi Pengcheng; Cai, Qian; ... Wang, Yinsheng The cytotoxicity of (-)-lomaiviticin A arises from Colis, Laureen C; Woo, R01ES005775 Nat Chem (2014 Jun) 24848236 2014 induction of double-strand breaks in DNA. Christina M; Hegan, Denise C; Li, Zhenwu; Glazer, Peter M; Herzon, Seth ... Toward hypoxia-selective DNA-alkylating agents built Johnson, Kevin M; R01ES021007 J Org Chem (2014 Aug 15) 25029663 2014 by grafting nitrogen mustards onto the bioreduc ... Parsons, Zachary D; Barnes, Charles L; Gates, Kent S Transcriptional bypass of regioisomeric ethylated You, Changjun; Wang, R01ES025121 Nucleic Acids Res (2014 25404131 2014 thymidine lesions by T7 RNA polymerase and human Pengcheng; Dai, Dec 16) R ... Xiaoxia; Wang, Yinsheng A quantitative mass spectrometry-based approach for Liu, Shuo; Wang, R01ES021007 Anal Chem (2013 Jul 16) 23789926 2013 assessing the repair of 8-methoxypsoralen-induce ... Yinsheng A reversible histone H3 acetylation cooperates with Kadyrova, Lyudmila Y; R01ES015869 PLoS Genet (2013 Oct) 24204308 2013 mismatch repair and replicative polymerases in m ... Mertz, Tony M; Zhang, Yu; Northam, Matthew R; Sheng, Ziwei; Lobachev, Ki ... A role for the MRN complex in ATR activation via Duursma, Anja M; R01ES016486 Mol Cell (2013 Apr 11) 23582259 2013 TOPBP1 recruitment. Driscoll, Robert; Elias, Josh E; Cimprich, Karlene A ATR phosphorylates SMARCAL1 to prevent Couch, Frank B; R01ES016486, Genes Dev (2013 Jul 15) 23873943 2013 replication fork collapse. Bansbach, Carol E; T32ES007028 Driscoll, Robert; Luzwick, Jessica W; Glick, Gloria G; Bétou ... Cognitive function and breast cancer: promise and Reuter-Lorenz, Patricia R01ES016486 Breast Cancer Res Treat 23053652 2013 potential insights from functional brain imaging. A; Cimprich, Bernadine (2013 Jan) Functional attributes of the Saccharomyces cerevisiae Busygina, Valeria; R01ES007061 DNA Repair (Amst) (2013 23769192 2013 meiotic recombinase Dmc1. Gaines, William A; Xu, Sep) Yuanyuan; Kwon, Youngho; Williams, Gareth J; Lin, Sh ... Hypoxia and DNA repair. Glazer, Peter M; Hegan, R01ES005775 Yale J Biol Med (2013 24348208 2013 Denise C; Lu, Yuhong; Dec 13) Czochor, Jennifer; Scanlon, Susan E NEK8 links the ATR-regulated replication stress Choi, Hyo Jei Claudia; R01ES016486 Mol Cell (2013 Aug 22) 23973373 2013 response and S phase CDK activity to renal ciliopath ... Lin, Jia-Ren; Vannier, Jean-Baptiste; Slaats, Gisela G; Kile, Andrew C; ... Nucleosome dynamics regulates DNA processing. Adkins, Nicholas L; R01ES007061 Nat Struct Mol Biol (2013 23728291 2013 Niu, Hengyao; Sung, Jul) Patrick; Peterson, Craig L On the formation and properties of interstrand Johnson, Kevin M; R01ES021007 J Am Chem Soc (2013 Jan 23215239 2013 DNA-DNA cross-links forged by reaction of an abasic Price, Nathan E; Wang, 23) s ... Jin; Fekry, Mostafa I; Dutta, Sanjay; Seiner, Derrick ... PHD domain from human SHPRH. Machado, Luciana E F; R01ES016486 J Biomol NMR (2013 23907177 2013 Pustovalova, Yulia; Aug) Kile, Andrew C; Pozhidaeva, Alexandra; Cimprich, Karl ... Pif1 helicase and Polýý promote Wilson, Marenda A; R01ES007061 Nature (2013 Oct 17) 24025768 2013 recombination-coupled DNA synthesis via bubble Kwon, YoungHo; Xu, migration. Yuanyuan; Chung, Woo-Hyun; Chi, Peter; Niu, Hengyao; May ... Postembryonic lineages of the Drosophila brain: I. Lovick, Jennifer K; R01ES029357 Dev Biol (2013 Dec 15) 23880429 2013 Development of the lineage-associated fiber tract ... Ngo, Kathy T; Omoto, Jaison J; Wong, Darren C; Nguyen, Joseph D; Hartenstei ... RIF1 in DNA break repair pathway choice. Daley, James M; Sung, R01ES007061 Mol Cell (2013 Mar 07) 23473603 2013 Patrick Role of replication protein A in double holliday Xue, Xiaoyu; Raynard, R01ES007061 J Biol Chem (2013 May 23543748 2013 junction dissolution mediated by the BLM-Topo IIIα- Steven; Busygina, 17) ... Valeria; Singh, Akhilesh K; Sung, Patrick Roles of DNA helicases in the mediation and Daley, James M; Niu, R01ES007061 Adv Exp Med Biol (2013) 23161012 2013 regulation of homologous recombination. Hengyao; Sung, Patrick A two-dimensional ERK-AKT signaling code for an Chen, Jia-Yun; Lin, R01ES016486 Mol Cell (2012 Jan 27) 22206868 2012 NGF-triggered cell-fate decision. Jia-Ren; Cimprich, Karlene A; Meyer, Tobias Finally, polyubiquitinated PCNA gets recognized. Zeman, Michelle K; R01ES016486 Mol Cell (2012 Aug 10) 22883622 2012 Cimprich, Karlene A Mechanistic insights into RAD51-associated protein 1 Dunlop, Myun Hwa; R01ES007061 J Biol Chem (2012 Apr 06) 22375013 2012 (RAD51AP1) action in homologous DNA repair. Dray, Eloïse; Zhao, Weixing; San Filippo, Joseph; Tsai, Miaw-Sheue; Leung, S ... Novel attributes of Hed1 affect dynamics and activity Busygina, Valeria; Saro, R01ES007061 J Biol Chem (2012 Jan 06) 22115747 2012 of the Rad51 presynaptic filament during meiot ... Dorina; Williams, Gareth; Leung, Wing-Kit; Say, Amanda F; Sehorn, Mic ... Role of DNA polymerases in repeat-mediated genome Shah, Kartik A; R01ES015869 Cell Rep (2012 Nov 29) 23142667 2012 instability. Shishkin, Alexander A; Voineagu, Irina; Pavlov, Youri I; Shcherbakova, Polina V ... Activation of protein kinase Tel1 through recognition Fukunaga, Kenzo; R01ES007061 Mol Cell Biol (2011 May) 21402778 2011 of protein-bound DNA ends. Kwon, Youngho; Sung, Patrick; Sugimoto, Katsunori Analyses of the yeast Rad51 recombinase A265V Chi, Peter; Kwon, R01ES007061 Nucleic Acids Res (2011 21558173 2011 mutant reveal different in vivo roles of Swi2-like fac ... YoungHo; Visnapuu, Aug) Mari-Liis; Lam, Isabel; Santa Maria, Sergio R; Zheng, Xiu ... Cell cycle regulation of DNA double-strand break end Chen, Xuefeng; Niu, R01ES007061 Nat Struct Mol Biol (2011 21841787 2011 resection by Cdk1-dependent Dna2 phosphorylatio ... Hengyao; Chung, Sep) Woo-Hyun; Zhu, Zhu; Papusha, Alma; Shim, Eun Yong; Lee, S ... Hypoxia-induced epigenetic regulation and silencing Lu, Yuhong; Chu, R01ES005775 Mol Cell Biol (2011 Aug) 21670155 2011 of the BRCA1 promoter. Adrian; Turker, Mitchell S; Glazer, Peter M Inhibition of hypoxia-induced miR-155 radiosensitizes Babar, Imran A; R01ES005775 Cancer Biol Ther (2011 22027557 2011 hypoxic lung cancer cells. Czochor, Jennifer; Nov 15) Steinmetz, Allison; Weidhaas, Joanne B; Glazer, Peter M; Sla ... Molecular basis for enhancement of the meiotic DMC1 Dray, Eloïse; Dunlop, R01ES007061 Proc Natl Acad Sci U S A 21307306 2011 recombinase by RAD51 associated protein 1 (RAD51 Myun Hwa; Kauppi, (2011 Mar 01) ... Liisa; San Filippo, Joseph; Wiese, Claudia; Tsai, Miaw ... Participation of translesion synthesis DNA Kochenova, O V; R01ES015869 Biochemistry (Mosc) 21568839 2011 polymerases in the maintenance of chromosome Soshkina, J V; (2011 Jan) integrity in ... Stepchenkova, E I; Inge-Vechtomov, S G; Shcherbakova, P V Processing of DNA structures via DNA unwinding and Zheng, Xiao-Feng; R01ES007061 DNA Repair (Amst) (2011 21880555 2011 branch migration by the S. cerevisiae Mph1 protei ... Prakash, Rohit; Saro, Oct 10) Dorina; Longerich, Simonne; Niu, Hengyao; Sung, Patric ... RAD51-associated protein 1 (RAD51AP1) interacts Dunlop, Myun Hwa; R01ES007061 J Biol Chem (2011 Oct 28) 21903585 2011 with the meiotic recombinase DMC1 through a Dray, Eloïse; Zhao, conserve ... Weixing; Tsai, Miaw-Sheue; Wiese, Claudia; Schild, David ... SHPRH and HLTF act in a damage-specific manner to Lin, Jia-Ren; Zeman, R01ES016486 Mol Cell (2011 Apr 22) 21396873 2011 coordinate different forms of postreplication repa ... Michelle K; Chen, Jia-Yun; Yee, Muh-Ching; Cimprich, Karlene A The non-canonical protein binding site at the Sharma, Neeru M; R01ES015869 J Biol Chem (2011 Sep 23) 21799021 2011 monomer-monomer interface of yeast proliferating cell Kochenova, Olga V; ... Shcherbakova, Polina V The Rad50 coiled-coil domain is indispensable for Hohl, Marcel; Kwon, R01ES007061 Nat Struct Mol Biol (2011 21892167 2011 Mre11 complex functions. Youngho; Galván, Sep 04) Sandra Muñoz; Xue, Xiaoyu; Tous, Cristina; Aguilera, Andr ... A cancer-associated DNA polymerase delta variant Daee, Danielle L; R01ES015869 Proc Natl Acad Sci U S A 19966286 2010 modeled in yeast causes a catastrophic increase in ... Mertz, Tony M; (2010 Jan 5) Shcherbakova, Polina V Checkpoint recovery after DNA damage: a rolling stop Duursma, Anja M; R01ES016486 EMBO Rep (2010 Jun) 20467435 2010 for CDKs. Cimprich, Karlene A Continued primer synthesis at stalled replication forks Van, Christopher; Yan, R01ES016486 J Cell Biol (2010 Apr 19) 20385778 2010 contributes to checkpoint activation. Shan; Michael, W Matthew; Waga, Shou; Cimprich, Karlene A Crystal structures of RMI1 and RMI2, two OB-fold Wang, Feng; Yang, R01ES007061 Structure (2010 Sep 08) 20826342 2010 regulatory subunits of the BLM complex. Yuting; Singh, Thiyam Ramsing; Busygina, Valeria; Guo, Rong; Wan, Ke; Wang, ... DNA polymerases at the eukaryotic fork-20 years later. Pavlov, Youri I; R01ES015869 Mutat Res (2010 Mar 01) 19682465 2010 Shcherbakova, Polina V Enhancement of RAD51 recombinase activity by the Dray, Eloïse; Etchin, R01ES007061 Nat Struct Mol Biol (2010 20871616 2010 tumor suppressor PALB2. Julia; Wiese, Claudia; Oct) Saro, Dorina; Williams, Gareth J; Hammel, Michal; ... Inhibition of poly(ADP-ribose) polymerase Hegan, Denise Campisi; R01ES005775 Proc Natl Acad Sci U S A 20133863 2010 down-regulates BRCA1 and RAD51 in a pathway Lu, Yuhong; Stachelek, (2010 Feb 02) mediated by E2 ... Gregory C; Crosby, Meredith E; Bindra, Ranjit S; ... Mechanism of the ATP-dependent DNA end-resection Niu, Hengyao; Chung, R01ES007061 Nature (2010 Sep 2) 20811460 2010 machinery from Saccharomyces cerevisiae. Woo-Hyun; Zhu, Zhu; Kwon, Youngho; Zhao, Weixing; Chi, Peter; Prakash, R ... MHF1-MHF2, a histone-fold-containing protein Singh, Thiyam R01ES007061 Mol Cell (2010 Mar 26) 20347429 2010 complex, participates in the Fanconi anemia pathway Ramsing; Saro, Dorina; via ... Ali, Abdullah Mahmood; Zheng, Xiao-Feng; Du, Chang-hu; Kil ... Participation of DNA polymerase zeta in replication of Northam, Matthew R; R01ES015869 Genetics (2010 Jan) 19841096 2010 undamaged DNA in Saccharomyces cerevisiae. Robinson, Heather A; Kochenova, Olga V; Shcherbakova, Polina V Potentiation of temozolomide cytotoxicity by Stachelek, Gregory C; R01ES005775 Cancer Res (2010 Jan 01) 20028873 2010 inhibition of DNA polymerase beta is accentuated by Dalal, Shibani; Donigan, BRC ... Katherine A; Campisi Hegan, Denise; Sweasy, Joan ... Promotion and regulation of homologous Colavito, Sierra; R01ES007061 Methods (2010 Jul) 20156560 2010 recombination by DNA helicases. Prakash, Rohit; Sung, Patrick Rad52 SUMOylation affects the efficiency of the DNA Altmannova, Veronika; R01ES007061 Nucleic Acids Res (2010 20371517 2010 repair. Eckert-Boulet, Nadine; Aug) Arneric, Milica; Kolesar, Peter; Chaloupkova, Radk ... A genome-wide siRNA screen reveals diverse cellular Paulsen, Renee D; Soni, R01ES016486 Mol Cell (2009 Jul 31) 19647519 2009 processes and pathways that mediate genome stabi ... Deena V; Wollman, Roy; Hahn, Angela T; Yee, Muh-Ching; Guan, Anna; Hes ... Assay for human Rad51-mediated DNA displacement Raynard, Steven; Sung, R01ES007061 Cold Spring Harb Protoc 20147015 2009 loop formation. Patrick (2009 Jan) Cooperativity of Mus81.Mms4 with Rad54 in the Matulova, Petra; Marini, R01ES007061 J Biol Chem (2009 Mar 19129197 2009 resolution of recombination and replication intermedia Victoria; Burgess, 20) ... Rebecca C; Sisakova, Alexandra; Kwon, Youngho; Roth ... DNA damage tolerance: when it's OK to make Chang, Debbie J; R01ES016486 Nat Chem Biol (2009 Feb) 19148176 2009 mistakes. Cimprich, Karlene A Emerging roles of microRNAs in the molecular Crosby, Meredith E; R01ES005775 Curr Pharm Des (2009) 19925433 2009 responses to hypoxia. Devlin, Cecilia M; Glazer, Peter M; Calin, George A; Ivan, Mircea Functional interactions of meiotic recombination Chi, Peter; Kwon, R01ES007061 DNA Repair (Amst) (2009 19028606 2009 factors Rdh54 and Dmc1. Youngho; Moses, Dana Feb 1) N; Seong, Changhyun; Sehorn, Michael G; Singh, Akhilesh ... Functional significance of the Rad51-Srs2 complex in Colavito, Sierra; R01ES007061 Nucleic Acids Res (2009 19745052 2009 Rad51 presynaptic filament disruption. Macris-Kiss, Margaret; Nov) Seong, Changhyun; Gleeson, Olive; Greene, Eric C; Klei ... HARPing on about the DNA damage response during Driscoll, Robert; R01ES016486 Genes Dev (2009 Oct 15) 19833762 2009 replication. Cimprich, Karlene A Localization of recombination proteins and Srs2 Burgess, Rebecca C; R01ES007061 J Cell Biol (2009 Jun 15) 19506039 2009 reveals anti-recombinase function in vivo. Lisby, Michael; Altmannova, Veronika; Krejci, Lumir; Sung, Patrick; Rothste ... MicroRNA regulation of DNA repair gene expression Crosby, Meredith E; R01ES005775 Cancer Res (2009 Feb 01) 19141645 2009 in hypoxic stress. Kulshreshtha, Ritu; Ivan, Mircea; Glazer, Peter M Proliferating cell nuclear antigen uses two distinct Kochaniak, Anna B; R01ES016486 J Biol Chem (2009 Jun 26) 19411704 2009 modes to move along DNA. Habuchi, Satoshi; Loparo, Joseph J; Chang, Debbie J; Cimprich, Karlene A; Wa ... Regulation of Rad51 recombinase presynaptic Seong, Changhyun; R01ES007061 J Biol Chem (2009 Sep 04) 19605344 2009 filament assembly via interactions with the Rad52 Colavito, Sierra; Kwon, mediat ... Youngho; Sung, Patrick; Krejci, Lumir Role of the Rad52 amino-terminal DNA binding Shi, Idina; Hallwyl, R01ES007061 J Biol Chem (2009 Nov 19812039 2009 activity in DNA strand capture in homologous Swee C L; Seong, 27) recombinat ... Changhyun; Mortensen, Uffe; Rothstein, Rodney; Sung, Pat ... Structural transitions within human Rad51 Robertson, Ragan B; R01ES007061 Proc Natl Acad Sci U S A 19622740 2009 nucleoprotein filaments. Moses, Dana N; Kwon, (2009 Aug 4) YoungHo; Chan, Pamela; Chi, Peter; Klein, Hannah; Sun ... Visualizing the disassembly of S. cerevisiae Rad51 Robertson, Ragan B; R01ES007061 J Mol Biol (2009 May 15) 19327367 2009 nucleoprotein filaments. Moses, Dana N; Kwon, YoungHo; Chan, Pamela; Zhao, Weixing; Chi, Peter; Kle ... Yeast Mph1 helicase dissociates Rad51-made D-loops: Prakash, Rohit; Satory, R01ES007061 Genes Dev (2009 Jan 01) 19136626 2009 implications for crossover control in mitotic re ... Dominik; Dray, Eloïse; Papusha, Almas; Scheller, Jürgen; Kramer, Wilfr ... ATP-dependent chromatin remodeling by the Kwon, YoungHo; R01ES007061 J Biol Chem (2008 Apr 18) 18292093 2008 Saccharomyces cerevisiae homologous recombination Seong, Changhyun; Chi, factor R ... Peter; Greene, Eric C; Klein, Hannah; Sung, Patrick ATR: an essential regulator of genome integrity. Cimprich, Karlene A; R01ES016486 Nat Rev Mol Cell Biol 18594563 2008 Cortez, David (2008 Aug) Chronic hypoxia decreases synthesis of homologous Chan, Norman; R01ES005775 Cancer Res (2008 Jan 15) 18199558 2008 recombination proteins to offset chemoresistance a ... Koritzinsky, Marianne; Zhao, Helen; Bindra, Ranjit; Glazer, Peter M; Powell, Sim ... Interaction with RPA is necessary for Rad52 repair Plate, Iben; Hallwyl, R01ES007061 J Biol Chem (2008 Oct 24) 18703507 2008 center formation and for its mediator activity. Swee C L; Shi, Idina; Krejci, Lumir; Müller, Christian; Albertsen, Line; ... Molecular anatomy of the recombination mediator Seong, Changhyun; R01ES007061 J Biol Chem (2008 May 18310075 2008 function of Saccharomyces cerevisiae Rad52. Sehorn, Michael G; 02) Plate, Iben; Shi, Idina; Song, Binwei; Chi, Peter; Morten ... Rad52 multimerization is important for its nuclear Plate, Iben; Albertsen, R01ES007061 DNA Repair (Amst) (2008 17888746 2008 localization in Saccharomyces cerevisiae. Line; Lisby, Michael; Jan 1) Hallwyl, Swee C L; Feng, Qi; Seong, Changhyun; R ... Analyzing the ATR-mediated checkpoint using Lupardus, Patrick J; R01ES016486 Methods (2007 Feb) 17189864 2007 Xenopus egg extracts. Van, Christopher; Cimprich, Karlene A Bipartite stimulatory action of the Hop2-Mnd1 Chi, Peter; San Filippo, R01ES007061 Genes Dev (2007 Jul 15) 17639080 2007 complex on the Rad51 recombinase. Joseph; Sehorn, Michael G; Petukhova, Galina V; Sung, Patrick Co-repression of mismatch repair gene expression by Bindra, Ranjit S; Glazer, R01ES005775 Cancer Lett (2007 Jul 8) 17275176 2007 hypoxia in cancer cells: role of the Myc/Max net ... Peter M Lessons from 50 years of SOS DNA-damage-induced Schlacher, Katharina; R01ES029680 Nat Rev Mol Cell Biol 17551516 2007 mutagenesis. Goodman, Myron F (2007 07) Probing ATR activation with model DNA templates. Cimprich, Karlene A R01ES016486 Cell Cycle (2007 Oct 01) 17700074 2007 Repression of RAD51 gene expression by E2F4/p130 Bindra, R S; Glazer, P R01ES005775 Oncogene (2007 Mar 29) 17001309 2007 complexes in hypoxia. M Role of Dnl4-Lif1 in nonhomologous end-joining Zhang, Yu; Hefferin, R01ES007061 Nat Struct Mol Biol (2007 17589524 2007 repair complex assembly and suppression of Melissa L; Chen, Ling; Jul) homologous ... Shim, Eun Yong; Tseng, Hui-Min; Kwon, Youngho; Sun ... The ATR pathway: fine-tuning the fork. Paulsen, Renee D; R01ES016486 DNA Repair (Amst) (2007 17531546 2007 Cimprich, Karlene A Jul 01) The structural determinants of checkpoint activation. MacDougall, Christina R01ES016486 Genes Dev (2007 Apr 15) 17437996 2007 A; Byun, Tony S; Van, Christopher; Yee, Muh-ching; Cimprich, Karlene A Basal repression of BRCA1 by multiple E2Fs and Bindra, Ranjit S; Glazer, R01ES005775 Cancer Biol Ther (2006 17106239 2006 pocket proteins at adjacent E2F sites. Peter M Oct) CHK2-dependent phosphorylation of BRCA1 in Gibson, Shannon L; R01ES005775 Radiat Res (2006 Oct) 17007555 2006 hypoxia. Bindra, Ranjit S; Glazer, Peter M Differing patterns of genetic instability in mice Hegan, Denise Campisi; R01ES005775 Carcinogenesis (2006 Dec) 16728433 2006 deficient in the mismatch repair genes Pms2, Mlh1, ... Narayanan, Latha; Jirik, Frank R; Edelmann, Winfried; Liskay, R Michael; ... Monoubiquitination of proliferating cell nuclear Chang, Debbie J; R01ES016486 J Biol Chem (2006 Oct 27) 16959771 2006 antigen induced by stalled replication requires unc ... Lupardus, Patrick J; Cimprich, Karlene A Overexpression of the DNA mismatch repair factor, Gibson, Shannon L; R01ES005775 Cancer Lett (2006 Dec 8) 16426742 2006 PMS2, confers hypermutability and DNA damage Narayanan, Latha; toler ... Hegan, Denise Campisi; Buermeyer, Andrew B; Liskay, R Mich ... RecA acts in trans to allow replication of damaged Schlacher, Katharina; R01ES029680 Nature (2006 Aug 24) 16929290 2006 DNA by DNA polymerase V. Cox, Michael M; Woodgate, Roger; Goodman, Myron F Recombination mediator and Rad51 targeting activities San Filippo, Joseph; R01ES007061 J Biol Chem (2006 Apr 28) 16513631 2006 of a human BRCA2 polypeptide. Chi, Peter; Sehorn, Michael G; Etchin, Julia; Krejci, Lumir; Sung, Patric ... Roles of ATP binding and ATP hydrolysis in human Chi, Peter; Van Komen, R01ES007061 DNA Repair (Amst) (2006 16388992 2006 Rad51 recombinase function. Stephen; Sehorn, Mar 7) Michael G; Sigurdsson, Stefan; Sung, Patrick Yeast recombination factor Rdh54 functionally Chi, Peter; Kwon, R01ES007061 J Biol Chem (2006 Sep 08) 16831867 2006 interacts with the Rad51 recombinase and catalyzes Youngho; Seong, Rad ... Changhyun; Epshtein, Anastasiya; Lam, Isabel; Sung, Patrick; ... Effect of amino acid substitutions in the rad50 ATP Chen, Ling; Trujillo, R01ES007061 J Biol Chem (2005 Jan 28) 15546877 2005 binding domain on DNA double strand break repair ... Kelly M; Van Komen, Stephen; Roh, Dong Hyun; Krejci, Lumir; Lewis, L Kev ... Hypoxia down-regulates DNA double strand break Meng, Alice X; Jalali, R01ES005775 Radiother Oncol (2005 16026872 2005 repair gene expression in prostate cancer cells. Farid; Cuddihy, Aug) Andrew; Chan, Norman; Bindra, Ranjit S; Glazer, Peter M ... Hypoxia-induced down-regulation of BRCA1 Bindra, Ranjit S; R01ES005775 Cancer Res (2005 Dec 15) 16357170 2005 expression by E2Fs. Gibson, Shannon L; Meng, Alice; Westermark, Ulrica; Jasin, Maria; Pierce, An ... Hypoxia-induced phosphorylation of Chk2 in an Gibson, Shannon L; R01ES005775 Cancer Res (2005 Dec 1) 16322218 2005 ataxia telangiectasia mutated-dependent manner. Bindra, Ranjit S; Glazer, Peter M Saccharomyces cerevisiae MPH1 gene, required for Prakash, Rohit; Krejci, R01ES007061 J Biol Chem (2005 Mar 15634678 2005 homologous recombination-mediated mutation Lumir; Van Komen, 04) avoidanc ... Stephen; Anke Schürer, Kirsten; Kramer, Wilfried; Sun ... Cell-interdependent cisplatin killing by Jensen, Ryan; Glazer, R01ES005775 Proc Natl Acad Sci U S A 15069205 2004 Ku/DNA-dependent protein kinase signaling Peter M (2004 Apr 20) transduced throug ... Differential arrangements of conserved building de Jager, Martijn; R01ES007061 J Mol Biol (2004 Jun 11) 15165861 2004 blocks among homologs of the Rad50/Mre11 DNA Trujillo, Kelly M; Sung, repair ... Patrick; Hopfner, Karl-Peter; Carney, James P; Tain ... Down-regulation of Rad51 and decreased homologous Bindra, Ranjit S; R01ES005775 Mol Cell Biol (2004 Oct) 15367671 2004 recombination in hypoxic cancer cells. Schaffer, Paul J; Meng, Alice; Woo, Jennifer; Måseide, Kårstein; Roth, Matt ... Meiotic recombination: an affair of two recombinases. Sehorn, Michael G; R01ES007061 Cell Cycle (2004 Nov) 15547324 2004 Sung, Patrick Multiple interactions with the Rad51 recombinase Raschle, Markus; Van R01ES007061 J Biol Chem (2004 Dec 15465810 2004 govern the homologous recombination function of Rad Komen, Stephen; Chi, 10) ... Peter; Ellenberger, Tom; Sung, Patrick Physical and functional interaction between the Motycka, Teresa A; R01ES007061 J Biol Chem (2004 Apr 02) 14734547 2004 XPF/ERCC1 endonuclease and hRad52. Bessho, Tadayoshi; Post, Sean M; Sung, Patrick; Tomkinson, Alan E Role of ATP hydrolysis in the antirecombinase Krejci, Lumir; Macris, R01ES007061 J Biol Chem (2004 May 15047689 2004 function of Saccharomyces cerevisiae Srs2 protein. Margaret; Li, Ying; Van 28) Komen, Stephen; Villemain, Jana; Ellenberger, T ... Role of the nuclease activity of Saccharomyces Lewis, L Kevin; Storici, R01ES007061 Genetics (2004 Apr) 15126391 2004 cerevisiae Mre11 in repair of DNA double-strand Francesca; Van Komen, break ... Stephen; Calero, Shanna; Sung, Patrick; Resnick, ... ATPase and DNA helicase activities of the Van Komen, Stephen; R01ES007061 J Biol Chem (2003 Nov 12966095 2003 Saccharomyces cerevisiae anti-recombinase Srs2. Reddy, Mothe Sreedhar; 07) Krejci, Lumir; Klein, Hannah; Sung, Patrick Decreased expression of the DNA mismatch repair Mihaylova, Valia T; R01ES005775 Mol Cell Biol (2003 May) 12697826 2003 gene Mlh1 under hypoxic stress in mammalian cells. Bindra, Ranjit S; Yuan, Jianling; Campisi, Denise; Narayanan, Latha; Jensen ... Rad51 recombinase and recombination mediators. Sung, Patrick; Krejci, R01ES007061 J Biol Chem (2003 Oct 31) 12912992 2003 Lumir; Van Komen, Stephen; Sehorn, Michael G Yeast xrs2 binds DNA and helps target rad50 and Trujillo, Kelly M; Roh, R01ES007061 J Biol Chem (2003 Dec 14522986 2003 mre11 to DNA ends. Dong Hyun; Chen, 05) Ling; Van Komen, Stephen; Tomkinson, Alan; Sung, Patr ... Functional cross-talk among Rad51, Rad54, and Van Komen, Stephen; R01ES007061 J Biol Chem (2002 Nov 12226081 2002 replication protein A in heteroduplex DNA joint Petukhova, Galina; 15) format ... Sigurdsson, Stefan; Sung, Patrick Interaction with Rad51 is indispensable for Krejci, Lumir; Song, R01ES007061 J Biol Chem (2002 Oct 18) 12171935 2002 recombination mediator function of Rad52. Binwei; Bussen, Wendy; Rothstein, Rodney; Mortensen, Uffe H; Sung, Patric ... ATM-dependent expression of the insulin-like growth Peretz, S; Jensen, R; R01ES005775 Proc Natl Acad Sci U S A 11172010 2001 factor-I receptor in a pathway regulating radiat ... Baserga, R; Glazer, P M (2001 Feb 13) Basis for avid homologous DNA strand exchange by Sigurdsson, S; Trujillo, R01ES007061 J Biol Chem (2001 Mar 11124265 2001 human Rad51 and RPA. K; Song, B; Stratton, S; 23) Sung, P DNA pairing and strand exchange by the Escherichia Rice, K P; Eggler, A L; R01ES007061 J Biol Chem (2001 Oct 19) 11504729 2001 coli RecA and yeast Rad51 proteins without ATP hy ... Sung, P; Cox, M M
DNA structure-specific nuclease activities in the Trujillo, K M; Sung, P R01ES007061 J Biol Chem (2001 Sep 21) 11454871 2001 Saccharomyces cerevisiae Rad50*Mre11 complex. Hypermutability to ionizing radiation in mismatch Xu, X S; Narayanan, L; R01ES005775 Cancer Res (2001 May 1) 11325851 2001 repair-deficient, Pms2 knockout mice. Dunklee, B; Liskay, R M; Glazer, P M Mediator function of the human Rad51B-Rad51C Sigurdsson, S; Van R01ES007061 Genes Dev (2001 Dec 15) 11751636 2001 complex in Rad51/RPA-catalyzed DNA strand Komen, S; Bussen, W; exchange. Schild, D; Albala, J S; Sung, P Promotion of Dnl4-catalyzed DNA end-joining by the Chen, L; Trujillo, K; R01ES007061 Mol Cell (2001 Nov) 11741545 2001 Rad50/Mre11/Xrs2 and Hdf1/Hdf2 complexes. Ramos, W; Sung, P; Tomkinson, A E Structure of the Rad50 x Mre11 DNA repair complex Anderson, D E; Trujillo, R01ES007061 J Biol Chem (2001 Oct 05) 11470800 2001 from Saccharomyces cerevisiae by electron microsco K M; Sung, P; Erickson, ... H P Functional interactions among yeast Rad51 Song, B; Sung, P R01ES007061 J Biol Chem (2000 May 10748203 2000 recombinase, Rad52 mediator, and replication protein 26) A in ... Interactions of the DNA ligase IV-XRCC4 complex Chen, L; Trujillo, K; R01ES007061 J Biol Chem (2000 Aug 10854421 2000 with DNA ends and the DNA-dependent protein Sung, P; Tomkinson, A 25) kinase. E Ionizing radiation-induced apoptosis via separate Zeng, M; Narayanan, L; R01ES005775 Cancer Res (2000 Sep 1) 10987303 2000 Pms2- and p53-dependent pathways. Xu, X S; Prolla, T A; Liskay, R M; Glazer, P M Mutagenesis in PMS2- and MSH2-deficient mice Andrew, S E; Xu, X S; R01ES005775 Carcinogenesis (2000 Jul) 10874005 2000 indicates differential protection from transversions an Baross-Francis, A; ... Narayanan, L; Milhausen, K; Liskay, R M; Jirik, F R; ... Promotion of Rad51-dependent D-loop formation by Petukhova, G; Sung, P; R01ES007061 Genes Dev (2000 Sep 01) 10970884 2000 yeast recombination factor Rdh54/Tid1. Klein, H Recombination factors of Saccharomyces cerevisiae. Sung, P; Trujillo, K M; R01ES007061 Mutat Res (2000 Jun 30) 10915877 2000 Van Komen, S Superhelicity-driven homologous DNA pairing by Van Komen, S; R01ES007061 Mol Cell (2000 Sep) 11030336 2000 yeast recombination factors Rad51 and Rad54. Petukhova, G; Sigurdsson, S; Stratton, S; Sung, P Different mutator phenotypes in Mlh1- versus Yao, X; Buermeyer, A R01ES005775 Proc Natl Acad Sci U S A 10359802 1999 Pms2-deficient mice. B; Narayanan, L; Tran, (1999 Jun 08) D; Baker, S M; Prolla, T A; Glazer, P M; Liskay, ... Single strand DNA binding and annealing activities in Petukhova, G; Stratton, R01ES007061 J Biol Chem (1999 Nov 10567339 1999 the yeast recombination factor Rad59. S A; Sung, P 26) The Tyr-265-to-Cys mutator mutant of DNA Clairmont, C A; R01ES005775 Proc Natl Acad Sci U S A 10449735 1999 polymerase beta induces a mutator phenotype in Narayanan, L; Sun, K (1999 Aug 17) mouse LN12 c ... W; Glazer, P M; Sweasy, J B Yeast Rad54 promotes Rad51-dependent homologous Petukhova, G; Van R01ES007061 J Biol Chem (1999 Oct 08) 10506208 1999 DNA pairing via ATP hydrolysis-driven change in Komen, S; Vergano, S; DNA ... Klein, H; Sung, P Nuclease activities in a complex of human Trujillo, K M; Yuan, S R01ES007061 J Biol Chem (1998 Aug 9705271 1998 recombination and DNA repair factors Rad50, Mre11, S; Lee, E Y; Sung, P 21) and p95 ... Elevated levels of mutation in multiple tissues of mice Narayanan, L; Fritzell, J R01ES005775 Proc Natl Acad Sci U S A 9096356 1997 deficient in the DNA mismatch repair gene Pm ... A; Baker, S M; Liskay, (1997 Apr 01) R M; Glazer, P M Function of yeast Rad52 protein as a mediator between Sung, P R01ES007061 J Biol Chem (1997 Nov 9353267 1997 replication protein A and the Rad51 recombinas ... 07) Insulin-like growth factor-I receptor overexpression Turner, B C; Haffty, B R01ES005775 Cancer Res (1997 Aug 1) 9242428 1997 mediates cellular radioresistance and local bre ... G; Narayanan, L; Yuan, J; Havre, P A; Gumbs, A A; Kaplan, L; Burgaud, ... Role of DNA mismatch repair in the cytotoxicity of Fritzell, J A; Narayanan, R01ES005775 Cancer Res (1997 Nov 15) 9371516 1997 ionizing radiation. L; Baker, S M; Bronner, C E; Andrew, S E; Prolla, T A; Bradley, A; ... Yeast Rad55 and Rad57 proteins form a heterodimer Sung, P R01ES007061 Genes Dev (1997 May 01) 9159392 1997 that functions with replication protein A to promo ... Dual requirement for the yeast MMS19 gene in DNA Lauder, S; Bankmann, R01ES007061 Mol Cell Biol (1996 Dec) 8943333 1996 repair and RNA polymerase II transcription. M; Guzder, S N; Sung, P; Prakash, L; Prakash, S Frequent spontaneous deletions at a shuttle vector Leach, E G; Gunther, E R01ES005775 Mutagenesis (1996 Jan) 8671715 1996 locus in transgenic mice. J; Yeasky, T M; Gibson, L H; Yang-Feng, T L; Glazer, P M Genetic instability induced by the tumor Reynolds, T Y; R01ES005775 Cancer Res (1996 Dec 15) 8971187 1996 microenvironment. Rockwell, S; Glazer, P M Mutagenesis by third-strand-directed psoralen adducts Raha, M; Wang, G; R01ES005775 Proc Natl Acad Sci U S A 8610147 1996 in repair-deficient human cells: high frequenc ... Seidman, M M; Glazer, (1996 Apr 02) P M Mutagenesis in mammalian cells induced by triple Wang, G; Seidman, M R01ES005775 Science (1996 Feb 09) 8628995 1996 helix formation and transcription-coupled repair. M; Glazer, P M Recombination induced by triple-helix-targeted DNA Faruqi, A F; Seidman, R01ES005775 Mol Cell Biol (1996 Dec) 8943337 1996 damage in mammalian cells. M M; Segal, D J; Carroll, D; Glazer, P M Targeted mutagenesis mediated by the triple helix Glazer, P M; Wang, G; R01ES005775 Methods Mol Biol (1996) 8849999 1996 formation. Havre, P A; Gunther, E J Tissue specificity of spontaneous point mutations in Leach, E G; Narayanan, R01ES005775 Environ Mol Mutagen 8991078 1996 lambda supF transgenic mice. L; Havre, P A; Gunther, (1996) E J; Yeasky, T M; Glazer, P M Yeast Rad51 recombinase mediates polar DNA strand Sung, P; Stratton, S A R01ES007061 J Biol Chem (1996 Nov 8910403 1996 exchange in the absence of ATP hydrolysis. 08) Altered repair of targeted psoralen photoadducts in the Wang, G; Glazer, P M R01ES005775 J Biol Chem (1995 Sep 22) 7673252 1995 context of an oligonucleotide-mediated tripl ... DNA strand exchange mediated by a RAD51-ssDNA Sung, P; Robberson, D R01ES007061 Cell (1995 Aug 11) 7634335 1995 nucleoprotein filament with polarity opposite to that ... L
G:C transversions in X-irradiated mouse cells."> Yuan, J; Yeasky, T M; R01ES005775 Carcinogenesis (1995 Jan) 7834808 1995 Frequent T:A-->G:C transversions in X-irradiated Rhee, M C; Glazer, P M mouse cells. Induction of p53 in mouse cells decreases mutagenesis Yuan, J; Yeasky, T M; R01ES005775 Carcinogenesis (1995 Oct) 7586125 1995 by UV radiation. Havre, P A; Glazer, P M Mutagenesis by 8-methoxypsoralen and Gunther, E J; Yeasky, T R01ES005775 Cancer Res (1995 Mar 15) 7882323 1995 5-methylangelicin photoadducts in mouse fibroblasts: M; Gasparro, F P; mutations ... Glazer, P M Targeted mutagenesis in mammalian cells mediated by Wang, G; Levy, D D; R01ES005775 Mol Cell Biol (1995 Mar) 7862165 1995 intracellular triple helix formation. Seidman, M M; Glazer, P M Site-specific targeting of psoralen photoadducts with a Gasparro, F P; Havre, P R01ES005775 Nucleic Acids Res (1994 8052539 1994 triple helix-forming oligonucleotide: charac ... A; Olack, G A; Gunther, Jul 25) E J; Glazer, P M High efficiency, restriction-deficient in vitro packaging Gunther, E J; Murray, N R01ES005775 Nucleic Acids Res (1993 8396240 1993 extracts for bacteriophage lambda DNA usin ... E; Glazer, P M Aug 11) Targeted mutagenesis of DNA using triple Havre, P A; Gunther, E R01ES005775 Proc Natl Acad Sci U S A 8356097 1993 helix-forming oligonucleotides linked to psoralen. J; Gasparro, F P; Glazer, (1993 Aug 15) P M Targeted mutagenesis of simian virus 40 DNA Havre, P A; Glazer, P M R01ES005775 J Virol (1993 Dec) 8230456 1993 mediated by a triple helix-forming oligonucleotide.