Anti-NDC1 (Aa 323-372) Polyclonal Antibody (DPABH-18457) This Product Is for Research Use Only and Is Not Intended for Diagnostic Use

Anti-NDC1 (aa 323-372) polyclonal antibody (DPABH-18457) This product is for research use only and is not intended for diagnostic use.

PRODUCT INFORMATION

Antigen Description NDC1 is a component of the nuclear pore complex (NPC), which plays a key role in de novo assembly and insertion of NPC in the nuclear envelope. NDC1 is required for NPC and nuclear envelope assembly, possibly by forming a link between the nuclear envelope membrane and soluble nucleoporins, thereby anchoring the NPC in the membrane. NDC1 colocalizes with p62 (NUP62) on the nuclear envelope at the nuclear rim. The protein has 6 transmembrane domains and several putative phosphorylation sites.

Immunogen Synthetic peptide corresponding to a region within the internal sequence amino acids 323-372 (PPIIKYLALQ DLMLLSQYSP SRRQEVFSLS QPGGHPHNWT AISRECLNLL) of Human NDC1, NP_060557.

Isotype IgG

Source/Host Rabbit

Species Reactivity Human

Purification Immunogen affinity purified

Conjugate Unconjugated

Applications WB

Format Liquid

Size 50 μg

Buffer Constituents: 2% Sucrose, PBS

Preservative None

Storage Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

GENE INFORMATION

Gene Name NDC1 NDC2 transmembrane nucleoporin [ Homo sapiens ]

45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected]

Synonyms NDC1; NDC1 transmembrane nucleoporin; NET3; TMEM48; nucleoporin NDC1; transmembrane protein 48; nuclear division cycle 1 homolog;

Entrez Gene ID 55706

Protein Refseq NP_001162023.1

UniProt ID Q9BTX1

Pathway Nuclear pore complex; RNA transport;

Function structural constituent of nuclear pore;

45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected]