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The Practice of Chemistry Education (Paper)
CHEMISTRY EDUCATION: THE PRACTICE OF CHEMISTRY EDUCATION RESEARCH AND PRACTICE (PAPER) 2004, Vol. 5, No. 1, pp. 69-87 Concept teaching and learning/ History and philosophy of science (HPS) Juan QUÍLEZ IES José Ballester, Departamento de Física y Química, Valencia (Spain) A HISTORICAL APPROACH TO THE DEVELOPMENT OF CHEMICAL EQUILIBRIUM THROUGH THE EVOLUTION OF THE AFFINITY CONCEPT: SOME EDUCATIONAL SUGGESTIONS Received 20 September 2003; revised 11 February 2004; in final form/accepted 20 February 2004 ABSTRACT: Three basic ideas should be considered when teaching and learning chemical equilibrium: incomplete reaction, reversibility and dynamics. In this study, we concentrate on how these three ideas have eventually defined the chemical equilibrium concept. To this end, we analyse the contexts of scientific inquiry that have allowed the growth of chemical equilibrium from the first ideas of chemical affinity. At the beginning of the 18th century, chemists began the construction of different affinity tables, based on the concept of elective affinities. Berthollet reworked this idea, considering that the amount of the substances involved in a reaction was a key factor accounting for the chemical forces. Guldberg and Waage attempted to measure those forces, formulating the first affinity mathematical equations. Finally, the first ideas providing a molecular interpretation of the macroscopic properties of equilibrium reactions were presented. The historical approach of the first key ideas may serve as a basis for an appropriate sequencing of -
The History of the Concept of Element, with Particular Reference to Humphry Davy
The Physical Sciences Initiative The history of the concept of element, with particular reference to Humphry Davy One of the problems highlighted when the recently implemented chemistry syllabus was being developed was the difficulty caused by starting the teaching of the course with atoms. The new syllabus offers a possible alternative teaching order that starts at the macroscopic level, and deals with elements. If this is done, the history of the idea of elements is dealt with at a very early stage. The concept of element originated with the ancient Greeks, notably Empedocles, who around 450 BC defined elements as the basic building blocks from which all other materials are made. He stated that there were four elements: earth, air, fire and water. Substances were said to change when elements break apart and recombine under the action of the forces of strife and love. Little progress was made in this area until the seventeenth century AD. The fruitless attempts of the alchemists to change base metals such as lead into gold and to find the “elixir of life” held back progress, although much chemical knowledge and expertise was gained. In 1661, 1 The Physical Sciences Initiative The Physical Sciences Initiative Robert Boyle defined an element as a substance that cannot be broken down into simpler materials. He cast doubt on the Greek elements, and provided a criterion for showing that a material was not an element. Robert Boyle Many elements were discovered during the next 100 years, but progress was delayed by the phlogiston hypothesis. According to this hypothesis, when a substance was burned it lost a substance called phlogiston to the air. -
References Title: in Search of El Dorado: John Dalton and the Origins of the Atomic Theory. Authors:Rocke, Alan J. Source
References Title: In Search of El Dorado: John Dalton and the Origins of the Atomic Theory. Authors: Rocke, Alan J. Source: Social Research ; Spring2005, Vol. 72 Issue 1, p125-158, 34p Abstract: This article examines how John Dalton formulated his atomic theory of matter. Dalton's work called forth a vigorous international research program that has a continuous history from 1803 t the present-- nanoscience long before the word became vogue. Almost from the start, that research program utterly transformed the science; moreover, it was atomistic theory that enabled chemistry, two generations after Dalton, to become the earliest example of a well-developed science-based theory acquiring the practical power to transform the world of technology and commerce. Dalton knew that water consists of 87.5 oxygen and 12.5 percent hydrogen by weight that is exactly seven times as much as oxygen as hydrogen. If one assumes, with Dalton, that the invisibly small water molecule consists of an atom of hydrogen united to an atom of oxygen, then every oxygen atom must weigh seven times as much as every hydrogen atom, for under these circumstances it is o bvious that the weight ratio of the atoms must match the composition of the compound. In contrast to Dalton, Humphry Davy and Jacob Berzelius assumed (in 1812 and 1814, respectively) that the formula for water was H2O rather than Dalton's HO. ISSN: 0037-783X Accession Number: 16900837 Persistent link to http://proxy.library.upenn.edu:2062/login.aspx?direct=true&db=aph&AN=16900837&site=ehost this record: live Title: Find More Like This J. -
Historical Development of the Periodic Classification of the Chemical Elements
THE HISTORICAL DEVELOPMENT OF THE PERIODIC CLASSIFICATION OF THE CHEMICAL ELEMENTS by RONALD LEE FFISTER B. S., Kansas State University, 1962 A MASTER'S REPORT submitted in partial fulfillment of the requirements for the degree FASTER OF SCIENCE Department of Physical Science KANSAS STATE UNIVERSITY Manhattan, Kansas 196A Approved by: Major PrafeLoor ii |c/ TABLE OF CONTENTS t<y THE PROBLEM AND DEFINITION 0? TEH-IS USED 1 The Problem 1 Statement of the Problem 1 Importance of the Study 1 Definition of Terms Used 2 Atomic Number 2 Atomic Weight 2 Element 2 Periodic Classification 2 Periodic Lav • • 3 BRIEF RtiVJiM OF THE LITERATURE 3 Books .3 Other References. .A BACKGROUND HISTORY A Purpose A Early Attempts at Classification A Early "Elements" A Attempts by Aristotle 6 Other Attempts 7 DOBEREBIER'S TRIADS AND SUBSEQUENT INVESTIGATIONS. 8 The Triad Theory of Dobereiner 10 Investigations by Others. ... .10 Dumas 10 Pettehkofer 10 Odling 11 iii TEE TELLURIC EELIX OF DE CHANCOURTOIS H Development of the Telluric Helix 11 Acceptance of the Helix 12 NEWLANDS' LAW OF THE OCTAVES 12 Newlands' Chemical Background 12 The Law of the Octaves. .........' 13 Acceptance and Significance of Newlands' Work 15 THE CONTRIBUTIONS OF LOTHAR MEYER ' 16 Chemical Background of Meyer 16 Lothar Meyer's Arrangement of the Elements. 17 THE WORK OF MENDELEEV AND ITS CONSEQUENCES 19 Mendeleev's Scientific Background .19 Development of the Periodic Law . .19 Significance of Mendeleev's Table 21 Atomic Weight Corrections. 21 Prediction of Hew Elements . .22 Influence -
A Brief Tour Into the History of Gravity: from Emocritus to Einstein
American Journal of Space Science 1 (1): 33-45, 2013 ISSN: 1948-9927 © 2013 Science Publications doi:10.3844/ajssp.2013.33.45 Published Online 1 (1) 2013 (http://www.thescipub.com/ajss.toc) A Brief Tour into the History of Gravity: From Emocritus to Einstein Panagiotis Papaspirou and Xenophon Moussas Department of Physics, Section of Astrophysics, Astronomy and Mechanics, University of Athens, Athens, Greece ABSTRACT The History of Gravity encompasses many different versions of the idea of the Gravitational interaction, which starts already from the Presocratic Atomists, continues to the doctrines of the Platonic and Neoplatonic School and of the Aristotelian School, passes through the works of John Philoponus and John Bouridan and reaches the visions of Johannes Kepler and Galileo Galilei. Then, the major breakthrough in the Theory of Motion and the Theory of Gravity takes place within the realm of Isaac Newton’s most famous Principia and of the work of Gottfried Leibniz, continues with the contributions of the Post- newtonians, such as Leonhard Euler, reaches the epoch of its modern formulation by Ernst Mach and other Giants of Physics and Philosophy of this epoch, enriches its structure within the work of Henry Poincare and finally culminates within the work of Albert Einstein, with the formulation of the Theory of Special Relativity and of General Relativity at the begin of the 20th century. The evolution of the Theory of General Relativity still continues up to our times, is rich in forms it takes and full of ideas of theoretical strength. Many fundamental concepts of the Epistemology and the History of Physics appear in the study of the Theory of Gravity, such as the notions of Space, of Time, of Motion, of Mass, in its Inertial, Active Gravitational and Passive Gravitational form, of the Inertial system of reference, of the Force, of the Field, of the Riemannian Geometry and of the Field Equations. -
Organocatalytic Asymmetric N-Sulfonyl Amide C-N Bond Activation to Access Axially Chiral Biaryl Amino Acids
ARTICLE https://doi.org/10.1038/s41467-020-14799-8 OPEN Organocatalytic asymmetric N-sulfonyl amide C-N bond activation to access axially chiral biaryl amino acids Guanjie Wang1, Qianqian Shi2, Wanyao Hu1, Tao Chen1, Yingying Guo1, Zhouli Hu1, Minghua Gong1, ✉ ✉ ✉ Jingcheng Guo1, Donghui Wei 2 , Zhenqian Fu 1,3 & Wei Huang1,3 1234567890():,; Amides are among the most fundamental functional groups and essential structural units, widely used in chemistry, biochemistry and material science. Amide synthesis and trans- formations is a topic of continuous interest in organic chemistry. However, direct catalytic asymmetric activation of amide C-N bonds still remains a long-standing challenge due to high stability of amide linkages. Herein, we describe an organocatalytic asymmetric amide C-N bonds cleavage of N-sulfonyl biaryl lactams under mild conditions, developing a general and practical method for atroposelective construction of axially chiral biaryl amino acids. A structurally diverse set of axially chiral biaryl amino acids are obtained in high yields with excellent enantioselectivities. Moreover, a variety of axially chiral unsymmetrical biaryl organocatalysts are efficiently constructed from the resulting axially chiral biaryl amino acids by our present strategy, and show competitive outcomes in asymmetric reactions. 1 Key Laboratory of Flexible Electronics & Institute of Advanced Materials, Jiangsu National Synergetic Innovation Center for Advanced Materials, Nanjing Tech University, 30 South Puzhu Road, Nanjing 211816, China. 2 College -
Substantive Change Report- Distance Education
Substantive Change Proposal Programs/Certificates Completed 50 Percent or More through Distance Education Submitted by: College of Alameda 555 Ralph Appezzato Memorial Parkway Alameda, CA 94501 Submitted to: Accrediting Commission for Community and Junior Colleges September 8, 2015 SUBSTANTIVE CHANGE REPORT: DISTANCE EDUCATION Table of Contents A. OVERVIEW OF SUBSTANTIVE CHANGE ..................................................................................... 3 1. Brief Description of the Proposed Change ............................................................................................ 3 2. Relationship to Institutional Mission ................................................................................................... 5 3. Rationale for the Request ..................................................................................................................... 6 B. DESCRIPTION OF THE EDUCATION PROGRAM AND DELIVERY MODE ........................ 11 1. Educational Purpose ............................................................................................................................ 11 2. Program Meets Eligibility Requirements, Accreditation Standards, and Commission Policies Related to Student Learning Programs and Services and Resources .................................................................. 12 C. DESCRIPTION OF THE PLANNING PROCESS ......................................................................... 16 1. Relationship to the Institution’s Planning, Evaluation and Stated Mission ....................................... -
Safe Hydroformylation of Aliphatic Alkene in a Flow Reactor
International Journal of Organic Chemistry, 2018, 8, 135-141 http://www.scirp.org/journal/ijoc ISSN Online: 2161-4695 ISSN Print: 2161-4687 Safe Hydroformylation of Aliphatic Alkene in a Flow Reactor Hisashi Masui, Eiki Honda, Sakura Niitsu, Mitsuru Shoji, Takashi Takahashi* Department of Pharmaceutical Sciences, Yokohama University of Pharmacy, Yokohama, Japan How to cite this paper: Masui, H., Honda, Abstract E., Niitsu, S., Shoji, M. and Takahashi, T. (2018) Safe Hydroformylation of Aliphatic Despite hydroformylation being a very efficient method for the transforma- Alkene in a Flow Reactor. International tion of alkenes, it is not commonly employed in laboratories owing to the Journal of Organic Chemistry, 8, 135-141. flammable/toxic nature of hydrogen and carbon monoxide gases and the ne- https://doi.org/10.4236/ijoc.2018.81009 cessity of high-pressure equipment in a batch system. Flow chemistry often Received: November 30, 2017 raises the safety profiles against high-pressure and toxic gases because the Accepted: March 6, 2018 diameter of the flow reactor is small. Herein, we show that aliphatic alkenes Published: March 9, 2018 can be safely hydroformylated in a flow reactor. In our flow method, although Copyright © 2018 by authors and the target hydroformylated product was obtained in a low yield (19%), toxic Scientific Research Publishing Inc. gases were safely treated using a flow reactor. Better yields could possibly be This work is licensed under the Creative achieved by recycling of the unreacted alkene. Commons Attribution International License (CC BY 4.0). http://creativecommons.org/licenses/by/4.0/ Keywords Open Access Hydroformylation, Flow Synthesis, Alkene, Carbon Monoxide, Aldehyde 1. -
Newton.Indd | Sander Pinkse Boekproductie | 16-11-12 / 14:45 | Pag
omslag Newton.indd | Sander Pinkse Boekproductie | 16-11-12 / 14:45 | Pag. 1 e Dutch Republic proved ‘A new light on several to be extremely receptive to major gures involved in the groundbreaking ideas of Newton Isaac Newton (–). the reception of Newton’s Dutch scholars such as Willem work.’ and the Netherlands Jacob ’s Gravesande and Petrus Prof. Bert Theunissen, Newton the Netherlands and van Musschenbroek played a Utrecht University crucial role in the adaption and How Isaac Newton was Fashioned dissemination of Newton’s work, ‘is book provides an in the Dutch Republic not only in the Netherlands important contribution to but also in the rest of Europe. EDITED BY ERIC JORINK In the course of the eighteenth the study of the European AND AD MAAS century, Newton’s ideas (in Enlightenment with new dierent guises and interpre- insights in the circulation tations) became a veritable hype in Dutch society. In Newton of knowledge.’ and the Netherlands Newton’s Prof. Frans van Lunteren, sudden success is analyzed in Leiden University great depth and put into a new perspective. Ad Maas is curator at the Museum Boerhaave, Leiden, the Netherlands. Eric Jorink is researcher at the Huygens Institute for Netherlands History (Royal Dutch Academy of Arts and Sciences). / www.lup.nl LUP Newton and the Netherlands.indd | Sander Pinkse Boekproductie | 16-11-12 / 16:47 | Pag. 1 Newton and the Netherlands Newton and the Netherlands.indd | Sander Pinkse Boekproductie | 16-11-12 / 16:47 | Pag. 2 Newton and the Netherlands.indd | Sander Pinkse Boekproductie | 16-11-12 / 16:47 | Pag. -
Catalytic Systems Based on Cp2zrx2 (X = Cl, H), Organoaluminum
catalysts Article Catalytic Systems Based on Cp2ZrX2 (X = Cl, H), Organoaluminum Compounds and Perfluorophenylboranes: Role of Zr,Zr- and Zr,Al-Hydride Intermediates in Alkene Dimerization and Oligomerization Lyudmila V. Parfenova 1,* , Pavel V. Kovyazin 1, Almira Kh. Bikmeeva 1 and Eldar R. Palatov 2 1 Institute of Petrochemistry and Catalysis of Russian Academy of Sciences, Prospekt Oktyabrya, 141, 450075 Ufa, Russia; [email protected] (P.V.K.); [email protected] (A.K.B.) 2 Bashkir State University, st. Zaki Validi, 32, 450076 Ufa, Russia; [email protected] * Correspondence: [email protected]; Tel.: +7-347-284-3527 i i Abstract: The activity and chemoselectivity of the Cp2ZrCl2-XAlBu 2 (X = H, Bu ) and [Cp2ZrH2]2- ClAlEt2 catalytic systems activated by (Ph3C)[B(C6F5)4] or B(C6F5)3 were studied in reactions with 1-hexene. The activation of the systems by B(C6F5)3 resulted in the selective formation of head- to-tail alkene dimers in up to 93% yields. NMR studies of the reactions of Zr complexes with organoaluminum compounds (OACs) and boron activators showed the formation of Zr,Zr- and Zr,Al-hydride intermediates, for which diffusion coefficients, hydrodynamic radii, and volumes were estimated using the diffusion ordered spectroscopy DOSY. Bis-zirconium hydride clusters of type x[Cp ZrH ·Cp ZrHCl·ClAlR ]·yRnAl(C F ) − were found to be the key intermediates of alkene 2 2 2 2 6 5 3 n dimerization, whereas cationic Zr,Al-hydrides led to the formation of oligomers. Citation: Parfenova, L.V.; Kovyazin, P.V.; Bikmeeva, A.K.; Palatov, E.R. -
Robert Wilhelm Bunsen Und Sein Heidelberger Laboratorium Heidelberg, 12
Historische Stätten der Chemie Robert Wilhelm Bunsen und sein Heidelberger Laboratorium Heidelberg, 12. Oktober 2011 Gesellschaft Deutscher Chemiker 1 Mit dem Programm „Historische Stätten der Chemie“ würdigt Robert Wilhelm Bunsen – die Gesellschaft Deutscher Chemiker (GDCh) Leistungen von geschichtlichem Rang in der Chemie. Als Orte der Erinnerung eine biographische Skizze werden Wirkungsstätten beteiligter Wissenschaftlerinnen und Wissenschaftler in einem feierlichen Akt ausgezeichnet. Eine Broschüre bringt einer breiten Öffentlichkeit deren wissenschaft- Bunsen war einer der Wegbereiter der Physikalischen Chemie liches Werk näher und stellt die Tragweite ihrer Arbeiten im und ein bedeutender Vertreter der anorganisch-analytischen aktuellen Kontext dar. Ziel dieses Programms ist es, die Erinne- Richtung. Seine wissenschaftliche Bedeutung liegt in der Ent- rung an das kulturelle Erbe der Chemie wach zu halten und die wicklung und Perfektionierung von Methoden und Instrumen- Chemie mit ihren historischen Wurzeln stärker in das Blickfeld ten. Diese Arbeitsschwerpunkte hat Bunsen von Beginn seiner der Öffentlichkeit zu rücken. Karriere an verfolgt und systematisch ausgebaut. Am 12. Oktober 2011 gedenken die GDCh, die Deutsche 1811 als jüngster von vier Söhnen einer bürgerlichen protestan- Bunsen-Gesellschaft für Physikalische Chemie (DBG), die Che- tischen Familie in Göttingen geboren, begann Bunsen dort 1828 mische Gesellschaft zu Heidelberg (ChGzH) und die Ruprecht- das Studium der Naturwissenschaften. Seine wichtigsten Lehrer Karls-Universität -
Reliable Determination of Amidicity in Acyclic Amides and Lactams Stephen A
Article pubs.acs.org/joc Reliable Determination of Amidicity in Acyclic Amides and Lactams Stephen A. Glover* and Adam A. Rosser Department of Chemistry, School of Science and Technology, University of New England, Armidale, NSW 2351, Australia *S Supporting Information ABSTRACT: Two independent computational methods have been used for determination of amide resonance stabilization and amidicities relative to N,N-dimethylacetamide for a wide range of acyclic and cyclic amides. The first method utilizes carbonyl substitution nitrogen atom replacement (COSNAR). The second, new approach involves determination of the difference in amide resonance between N,N-dimethylacetamide and the target amide using an isodesmic trans-amidation process and is calibrated relative to 1-aza-2-adamantanone with zero amidicity and N,N-dimethylace- tamide with 100% amidicity. Results indicate excellent coherence between the methods, which must be regarded as more reliable than a recently reported approach to amidicities based upon enthalpies of hydrogenation. Data for acyclic planar and twisted amides are predictable on the basis of the degrees of pyramidalization at nitrogen and twisting about the C−N bonds. Monocyclic lactams are predicted to have amidicities at least as high as N,N-dimethylacetamide, and the β-lactam system is planar with greater amide resonance than that of N,N- dimethylacetamide. Bicyclic penam/em and cepham/em scaffolds lose some amidicity in line with the degree of strain-induced pyramidalization at the bridgehead nitrogen and twist about the amide bond, but the most puckered penem system still retains substantial amidicity equivalent to 73% that of N,N-dimethylacetamide. ■ INTRODUCTION completed by a third resonance form, III, with no C−N pi Amide linkages are ubiquitous in proteins, peptides, and natural character and on account of positive polarity at carbon and the or synthetic molecules and in most of these they possess, electronegativity of nitrogen, must be destabilizing.