ALOX15B polyclonal antibody Symbol: ALOX15B

Gene Alias: 15-LOX-2 Catalog Number: PAB13608

Gene Summary: This gene encodes a member of the Regulatory Status: For research use only (RUO) family of structurally related nonheme iron Product Description: Rabbit polyclonal antibody raised dioxygenases involved in the production of fatty acid against recombinant ALOX15B . hydroperoxides. The encoded protein converts exclusively to Immunogen: Recombinant protein corresponding to 15S-hydroperoxyeicosatetraenoic acid, while human ALOX15B . metabolizing linoleic acid less effectively. This gene is located in a cluster of related and a pseudogene Host: Rabbit that spans approximately 100 kilobases on the short arm of 17. Alternatively spliced transcript Theoretical MW (kDa): 78.8 variants encoding different isoforms have been described. [provided by RefSeq] Reactivity: Human,Mouse References: Applications: ELISA, IHC-P, IP, WB 1. Molecular cloning and functional expression of a (See our web site product page for detailed applications phorbol ester-inducible 8S-lipoxygenase from mouse information) skin. Jisaka M, Kim RB, Boeglin WE, Nanney LB, Brash AR. J Biol Chem. 1997 Sep 26;272(39):24410-6. Protocols: See our web site at http://www.abnova.com/support/protocols.asp or product page for detailed protocols

Specificity: This rabbit antibody reacts specifically with 15-lipoxygenase form-2 in human tissues and 8-lipoxygenase in murine tissues. 15-Lipoxygenase Form-2 (15-LOX-2) is expressed primarily in lung tissue, hair roots, the prostate and the cornea and is a useful biomarker in studies.

Form: Liquid

Recommend Usage: ELISA Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) Immunoprecipitation Western Blot (1:1000) The optimal working dilution should be determined by the end user.

Storage Buffer: In antisera.

Storage Instruction: Store at -20°C. Aliquot to avoid repeated freezing and thawing.

Entrez GeneID: 247

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