Disposal Options for Specific Chemicals
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Appendix a Common Abbreviations Used in Medication
UNIVERSITY OF AMSTERDAM MASTERS THESIS Impact of Medication Grouping on Fall Risk Prediction in Elders: A Retrospective Analysis of MIMIC-III Critical Care Database Student: SRP Mentor: Noman Dormosh Dr. Martijn C. Schut Student No. 11412682 – SRP Tutor: Prof. dr. Ameen Abu-Hanna SRP Address: Amsterdam University Medical Center - Location AMC Department Medical Informatics Meibergdreef 9, 1105 AZ Amsterdam Practice teaching period: November 2018 - June 2019 A thesis submitted in fulfillment of the requirements for the degree of Master of Medical Informatics iii Abstract Background: Falls are the leading cause of injury in elderly patients. Risk factors for falls in- cluding among others history of falls, old age, and female gender. Research studies have also linked certain medications with an increased risk of fall in what is called fall-risk-increasing drugs (FRIDs), such as psychotropics and cardiovascular drugs. However, there is a lack of consistency in the definitions of FRIDs between the studies and many studies did not use any systematic classification for medications. Objective: The aim of this study was to investigate the effect of grouping medications at different levels of granularity of a medication classification system on the performance of fall risk prediction models. Methods: This is a retrospective analysis of the MIMIC-III cohort database. We created seven prediction models including demographic, comorbidity and medication variables. Medica- tions were grouped using the anatomical therapeutic chemical classification system (ATC) starting from the most specific scope of medications and moving up to the more generic groups: one model used individual medications (ATC level 5), four models used medication grouping at levels one, two, three and four of the ATC and one model did not include med- ications. -
Peroxy Compounds Human Health and Ecological Draft Risk Assessment DP 455445, 455446
Peroxy Compounds Human Health and Ecological Draft Risk Assessment DP 455445, 455446 UNITED STATES ENVIRONMENTAL PROTECTION AGENCY WASHINGTON, D.C. 20460 OFFICE OF CHEMICAL SAFETY AND POLLUTION PREVENTION MEMORANDUM Date: March 11, 2020 SUBJECT: Registration Review Draft Risk Assessment for the Peroxy Compounds PC Code: 000595, 063201, 063604, 063607, DP Barcode: 455445, 455446 063209, 128860 Decision No: 558073, 558074 Docket No: EPA-HQ-OPP-2009-0546 Regulatory Action: Registration Review Case No: 6059, 4072, 5081 Risk Assessment Type: DRA CAS No: 7722-84-1, 79-21-0, 33734-57-5, 15630-89-4, 10058-23-8, 70693-62-8 TO: Kendall Ziner, Chemical Review Manager Rick Fehir, Ph.D., Team Lead Rose Kyprianou, Branch Chief Regulatory Management Branch (RMB) II Antimicrobials Division (7510P) Office of Pesticide Programs FROM: Andrew Byro, Ph.D., Chemist Kathryn Korthauer, Biologist Timothy Dole, Industrial Hygienist Deborah Burgin, Ph.D., DABT, Toxicologist Risk Assessment and Science Support Branch Antimicrobials Division (7510P) Office of Pesticide Programs THROUGH: Judy Facey, Ph.D., Human Health Risk Assessment Process Leader MP for JF Diana Hsieh, Ecological Risk Assessment Process Leader MP for DH Timothy Leighton, Senior Science Advisor MP for TL Laura Parsons, Associate Branch Chief Melissa Panger, Ph.D., Branch Chief Risk Assessment and Science Support Branch Antimicrobials Division (7510P) This document provides the draft human health and ecological risk assessment conducted in support of the antimicrobial use sites of the following peroxy compounds: hydrogen peroxide, peracetic acid, peroxyoctanoic acid, and sodium percarbonate. Page 1 of 74 Peroxy Compounds Human Health and Ecological Draft Risk Assessment DP 455445, 455446 Although the peroxymonosulfate compounds were included in the peroxy compounds Final Work Plan (FWP), they will not be included in this risk assessment. -
Chemicals Used for Chemical Manufacturing Page 1 of 2
Chemicals used for Chemical Manufacturing Page 1 of 2 Acetic Acid (Glacial, 56%) Glycol Ether PMA Acetone Glycol Ether PNB Acrylic Acid Glycol Ether PNP Activated Carbon Glycol Ether TPM Adipic Acid Glycols Aloe Vera Grease Aluminum Stearate Gum Arabic Aluminum Sulfate Heat Transfer Fluids Amino Acid Heptane Ammonium Acetate Hexane Ammonium Bicarbonate Hydrazine Hydrate Ammonium Bifluoride Hydrochloric Acid (Muriatic) Ammonium Chloride Hydrogen Peroxide Ammonium Citrate Hydroquinone Ammonium Hydroxide Hydroxylamine Sulfate Ammonium Laureth Sulfate Ice Melter Ammonium Lauryl Sulfate Imidazole Ammonium Nitrate Isobutyl Acetate Ammonium Persulfate Isobutyl Alcohol Ammonium Silicofluoride Calcium Stearate Dipropylene Glycol Isopropanolamine Ammonium Sulfate Carboxymethylcellulose Disodium Phosphate Isopropyl Acetate Antifoams Caustic Potash D'Limonene Isopropyl Alcohol Antifreeze Caustic Soda (All Grades) Dodecylbenzene Sulfonic Acid Isopropyl Myristate Antimicrobials Caustic Soda (Beads, Prills) (DDBSA) Isopropyl Palmitate Antimony Oxide Cetyl Alcohol Dowfrost Itaconic Acid Aqua Ammonia Cetyl Palmitate Dowfrost HD Jojoba Oil Ascorbic Acid Chlorine, Granular Dowtherm SR-1 Keratin Barium Carbonate Chloroform Dowtherm 4000 Lactic Acid Barium Chloride Chromic Acid EDTA Lanolin Beeswax Citric Acid (Dry and Liquid) EDTA Plus Lauric Acid Bentonite Coal Epsom Salt Lauryl Alcohol Benzaldehyde Cocamide DEA Ethyl Acetate Lecithin Benzoic Acid Copper Nitrate Ethyl Alcohol (Denatured) Lime Benzyl Alcohol Copper Sulfate Ethylene Glycol Linoleic Acid Bicarbonate -
Chlorthalidone Is Superior to Potassium Citrate in Reducing Calcium Phosphate Stones and Increasing Bone Quality in Hypercalciuric Stone-Forming Rats
BASIC RESEARCH www.jasn.org Chlorthalidone Is Superior to Potassium Citrate in Reducing Calcium Phosphate Stones and Increasing Bone Quality in Hypercalciuric Stone-Forming Rats Nancy S. Krieger,1 John R. Asplin,2 Ignacio Granja,2 Felix M. Ramos,1 Courtney Flotteron,1 Luojing Chen,1 Tong Tong Wu,3 Marc D. Grynpas,4 and David A. Bushinsky1 1Division of Nephrology, Department of Medicine, University of Rochester School of Medicine and Dentistry, Rochester, New York; 2Litholink Corporation, Laboratory Corporation of America Holdings, Chicago, Illinois; 3Department of Biostatistics and Computational Biology, University of Rochester School of Medicine, Rochester, New York; and 4Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada ABSTRACT Background The pathophysiology of genetic hypercalciuric stone-forming rats parallels that of human idiopathic hypercalciuria. In this model, all animals form calcium phosphate stones. We previously found that chlorthalidone, but not potassium citrate, decreased stone formation in these rats. Methods To test whether chlorthalidone and potassium citrate combined would reduce calcium phos- phate stone formation more than either medication alone, four groups of rats were fed a fixed amount of a normal calcium and phosphorus diet, supplemented with potassium chloride (as control), potassium citrate, chlorthalidone (with potassium chloride to equalize potassium intake), or potassium citrate plus chlorthalidone. We measured urine every 6 weeks and assessed stone formation and bone quality at 18 weeks. Results Potassium citrate reduced urine calcium compared with controls, chlorthalidone reduced it fur- ther, and potassium citrate plus chlorthalidone reduced it even more. Chlorthalidone increased urine citrate and potassium citrate increased it even more; the combination did not increase it further. -
Ammonium Persulfate
SAFETY DATA SHEET Ammonium Persulfate Section 1. Identification GHS product identifier : Ammonium Persulfate Code : 76322 Other means of : ammonium persulphate; Peroxydisulfuric acid, diammonium salt; diammonium identification peroxodisulfate; Diammonium persulfate Supplier/Manufacturer : 3420 Central Expressway, Santa Clara CA 95051 In case of emergency : Chemtrec: 1 800 424 9300 Outside USA & Canada: +1 703 527 3887 Section 2. Hazards identification OSHA/HCS status : This material is considered hazardous by the OSHA Hazard Communication Standard (29 CFR 1910.1200). Classification of the : OXIDIZING SOLIDS - Category 3 substance or mixture ACUTE TOXICITY (oral) - Category 4 SKIN CORROSION/IRRITATION - Category 2 SERIOUS EYE DAMAGE/ EYE IRRITATION - Category 2 RESPIRATORY SENSITIZATION - Category 1 SKIN SENSITIZATION - Category 1 SPECIFIC TARGET ORGAN TOXICITY (SINGLE EXPOSURE) (Respiratory tract irritation) - Category 3 GHS label elements Hazard pictograms : Signal word : Danger Hazard statements : May intensify fire; oxidizer. Harmful if swallowed. Causes serious eye irritation. Causes skin irritation. May cause allergy or asthma symptoms or breathing difficulties if inhaled. May cause an allergic skin reaction. May cause respiratory irritation. Precautionary statements Prevention : Wear protective gloves. Wear eye or face protection. In case of inadequate ventilation wear respiratory protection. Keep away from heat. - No smoking. Keep away from clothing, incompatible materials and combustible materials. Take any precaution to avoid mixing with combustibles and other incompatible materials. Use only outdoors or in a well-ventilated area. Avoid breathing dust. Do not eat, drink or smoke when using this product. Wash hands thoroughly after handling. Contaminated work clothing should not be allowed out of the workplace. Response : IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing. -
Purified Sea Salt with Magnesium Carbonate
Cargill® Food Processing Salts Purified Sea Saltwith Magnesium Carbonate Product Description Physical Information Purified Sea Salt with Magnesium Carbonate This material is a food grade, granular, white crystalline Purified Sea Salt with Magnesium Carbonate sodium chloride product manufactured under stringent PHYSICAL MIN TARGET MAX process control procedures. Cargill Sea Salts are made from Pacific Ocean sea salt, which is harvested from ponds NaCl (%) 99.7 99.96 100 near the San Francisco Bay. Ca & Mg as Ca (%) 0.003 Sulfate as SO4 (%) 0.01 Product Application Water Insolubles (%) 0.025 0.01 Bulk Density (#cu/ft) 69 74 84 This material is intended for table and cooking use, as well as direct application in foods manufactured by the various Bulk Density (g/l) 1105 1185 1345 food processing industries. This material contains Surface Moisture (%) 0.02 Magnesium Carbonate, which is added to improve caking Magnesium Carbonate (%) 0.5 resistance and flowability. PERCENT PARTICLE SIZE MIN TARGET MAX Product Certifications DISTRIBUTION (SCREENS) Sieve - USS 30 Mesh Retained 0 40 50 Cargill® Sea Salts meet USDA, FDA and Food Chemicals Codex for food use. Sieve - USS 40 Mesh Retained 34 Sieve - USS 50 Mesh Retained 16 Cargill® Sea Salts are certified Kosher for Passover (OU-P) SieveCargill - USS 70 Mesh® RetainedSea Salt 8 by the Orthodox Union. Sieve - Retained on Pan 0 1 10 Made with Sun, Wind and Time Allergen Status Harvesting sea salt from San Francisco Bay today is similar to the salt-making process that has been used for centuries. In accordance with the 2004 USA Food Allergen Labeling and Consumer Protection Act (FALCPA), no allergen declarations are required for this product. -
Magnesium Sulfate
MAGNESIUM SULFATE Prepared at the 68th JECFA (2007), published in FAO JECFA Monographs 4 (2007), superseding the specifications prepared at the 63rd JECFA (2004) and published the Combined Compendium of Food Additive Specifications, FAO JECFA Monographs 1 (2005). An ADI “not specified” was established at the 68th JECFA (2007). SYNONYMS Epsom salt (heptahydrate); INS No.518 DEFINITION Magnesium sulfate occurs naturally in sea water, mineral springs and in minerals such as kieserite and epsomite. It is recovered from them or by reacting sulfuric acid and magnesium oxide. It is produced with one or seven molecules of water of hydration or in a dried form containing the equivalent of between 2 and 3 waters of hydration. Chemical names Magnesium sulfate C.A.S. number Monohydrate: 14168-73-1 Heptahydrate: 10034-99-8 Dried: 15244-36-7 Chemical formula Monohydrate: MgSO4.H2O Heptahydrate: MgSO4.7H2O Dried: MgSO4.xH2O, where x is the average hydration value (between 2 and 3) Formula weight Monohydrate: 138.38 Heptahydrate: 246.47 Assay Not less than 99.0 % and not more than 100.5% on the ignited basis DESCRIPTION Colourless crystals, granular crystalline powder or white powder. Crystals effloresce in warm, dry air. FUNCTIONAL USES Nutrient; flavour enhancer; firming agent; and processing aid (fermentation aid in the production of beer and malt beverages) CHARACTERISTICS IDENTIFICATION Solubility (Vol. 4) Freely soluble in water, very soluble in boiling water, and sparingly soluble in ethanol. Test for magnesium (Vol. 4) Passes test Test for sulfate (Vol. 4) Passes test PURITY Loss on ignition (Vol. 4) Monohydrate: between 13.0 and 16.0 %, Heptahydrate: between 40.0 and 52.0 %, Dried: between 22.0 and 32.0 % (105°, 2h, then 400° to constant weight) pH (Vol. -
Mechanosynthesis of Magnesium and Calcium Salt?Urea Ionic Cocrystal
Letter pubs.acs.org/journal/ascecg Mechanosynthesis of Magnesium and Calcium Salt−Urea Ionic Cocrystal Fertilizer Materials for Improved Nitrogen Management Kenneth Honer, Eren Kalfaoglu, Carlos Pico, Jane McCann, and Jonas Baltrusaitis* Department of Chemical and Biomolecular Engineering, Lehigh University, B336 Iacocca Hall, 111 Research Drive, Bethlehem, Pennsylvania 18015, United States *S Supporting Information ABSTRACT: Only 47% of the total fertilizer nitrogen applied to the environment is taken up by the plants whereas approximately 40% of the total fertilizer nitrogen lost to the environment reverts back into unreactive atmospheric dinitrogen that greatly affects the global nitrogen cycle including increased energy consumption for NH3 synthesis, as well as accumulation of nitrates in drinking water. In this letter, we provide a mechanochemical method of inorganic magnesium and calcium salt−urea ionic cocrystal synthesis to obtain enhanced stability nitrogen fertilizers. The solvent-free mechanochemical synthesis presented can result in a greater manufacturing process sustainability by reducing or eliminating the need for solution handling and evaporation. NH3 emission testing suggests that urea ionic cocrystals are capable of decreasing NH3 emissions to the environment when compared to pure urea, thus providing implications for a sustainable global solution to the management of the nitrogen cycle. KEYWORDS: Fertilizers, Nitrogen, urea, Mechanochemistry, Cocrystal, pXRD, NH3 Emissions, Stability ■ INTRODUCTION ammonia as opposed to up to 61.1% of soil treated with urea 7,8 fi only, which suggests that major improvements to the global Atmospheric dinitrogen, N2, xation to synthesize ammonia, 9,10 ’ 1 nitrogen cycle are achievable. Additionally, urea molecular NH3, consumes more than 1% of the world s primary energy. -
Chromatographic Separation of Alkaline Earth Metals Using Alpha-Hydroxyisobutyric Acid
AN ABSTRACT OF THE THESIS OF JOHN ARTHUR HAUSCHILD for the MASTER OF SCIENCE (Name) (Degree) in CHEMISTRY (ANALYTICAL) presented on (Major) Title: CHROMATOGRAPHIC SEPARATION OF ALKALINE EARTH METALS USING ALPHA-HYDROXYISOBUYRIC ACID Abstract approved: Redacted for Privacy Max B. Williams A systematic study of the elution of magnesium and calcium from Dowex 50 X 8 resin using a-hydroxyisobutyric acid (a-HIBA) at various pH values and concentrations, indicated that the difference in the equilibrium distribution coefficients of these two elements was large enough for a good separation.This fact was applied to develop a chromatographic procedure for the separationof milligram quantities of magnesium, calcium, strontium, and barium.After magnesium was eluted with 0. 22M a-HIBA at pH 4. 5, thethree remaining elements were eluted by varying the concentration and pH of a-HIBAduring the course of the elution (exponential gradient elution).After its respec- tive elution, each alkaline earth metal was directly determined by atomic absorption spectroscopy.Using this method, several success- ful analyses of synthetic samples (similar to the composition of sea water) were performed.Yield determinations of the alkaline earth metals from these analyses were consistently greater than 93%, with the overall average yield being 98%. Chromatographic Separation of Alkaline Earth Metals Using Alpha-Hydroxyisobutyric Acid by John Arthur Haus child A THESIS submitted to Oregon State University in partial fulfillment of the requirements for the degree of Master -
Old Time Chemical Names
Old Time Chemical Names 1080------------------------------------------------Sodium fluroacetate 2-Propanone-------------------------------------Acetone Absinthe-------------------------------------------Distillate of worm wood Abstinthium--------------------------------------Distillate of worm wood Acarcia gum-------------------------------------Gum arabic Acetaldehyde------------------------------------Acetic aldehyde Acetate of alumina-----------------------------Aluminium acetate Acetate of ammonia---------------------------Ammonium acetate Acetate of amyl---------------------------------Amyl acetate Acetate of baryta-------------------------------Barium acetate Acetate of cobalt-------------------------------Cobalt acetate Acetate of copper------------------------------Copper acetate Acetate of ethyl---------------------------------Ethyl acetate Acetate of iron----------------------------------Iron acetate Acetate of lead----------------------------------Lead acetate Acetate of lime----------------------------------Calcium acetate Acetate of manganese------------------------Manganous acetate Acetate of oxide of ethyl---------------------Ethyl acetate Acetate of potassa-----------------------------Potassium acetate Acetate of potassium--------------------------Potassium acetate Acetate of protoxide of Manganese-------Manganous acetate Acetate of soda---------------------------------Sodium acetate Acetate of zinc----------------------------------Zinc acetate Acetic aid basic bismuth---------------------Bismuth subacetate CH3COOBiO Acetic -
Working with Hazardous Chemicals
A Publication of Reliable Methods for the Preparation of Organic Compounds Working with Hazardous Chemicals The procedures in Organic Syntheses are intended for use only by persons with proper training in experimental organic chemistry. All hazardous materials should be handled using the standard procedures for work with chemicals described in references such as "Prudent Practices in the Laboratory" (The National Academies Press, Washington, D.C., 2011; the full text can be accessed free of charge at http://www.nap.edu/catalog.php?record_id=12654). All chemical waste should be disposed of in accordance with local regulations. For general guidelines for the management of chemical waste, see Chapter 8 of Prudent Practices. In some articles in Organic Syntheses, chemical-specific hazards are highlighted in red “Caution Notes” within a procedure. It is important to recognize that the absence of a caution note does not imply that no significant hazards are associated with the chemicals involved in that procedure. Prior to performing a reaction, a thorough risk assessment should be carried out that includes a review of the potential hazards associated with each chemical and experimental operation on the scale that is planned for the procedure. Guidelines for carrying out a risk assessment and for analyzing the hazards associated with chemicals can be found in Chapter 4 of Prudent Practices. The procedures described in Organic Syntheses are provided as published and are conducted at one's own risk. Organic Syntheses, Inc., its Editors, and its Board of Directors do not warrant or guarantee the safety of individuals using these procedures and hereby disclaim any liability for any injuries or damages claimed to have resulted from or related in any way to the procedures herein. -
Product Information Calcium Nitrite 94% Solution
Product Information Calcium Nitrite 94% Solution Product Description: This product is a white powder composed of 94% calcium nitrite. It is a strong oxidising agent and is highly soluble allowing it to promote hydration of minerals in cement and thus its application as an antifreeze additive in cement. Applications: Calcium nitrite is used as a metal corrosion inhibitor for steel in reinforced concrete, antifreeze in cement. It can be used as a heavy oil detergent and in thermal energy storage for air conditioning. Chemical Formula: Ca(NO2)2 CAS No. : 13780-06-8 Specifications: Parameters (units) Specifications Calcium nitrite (%) ≥ 94 Calcium nitrate (%) ≤ 5 Calcium hydroxide (%) ≤ 1.0 Moisture (%) ≤ 1.0 Water insoluble (%) ≤ 1.0 Bisley International LLC 1790 Hughes Landing Boulevard Suite 400 The Woodlands 77380 TX USA Phone number: +1 (844) 424 7539 Emergency telephone number: +1 855 237 5573 bisleyinternational.com Copyright 2021 Bisley & Co. Pty Ltd. All rights reserved Packaging: Packaging options are available upon enquiry. Storage: Product should be stored in a dry place in sealed, original packaging away from direct sunlight. Safety: For further safety information refer to product SDS available from your Bisley International contact. Disclaimer: This document is for information purposes only. Customers are responsible for testing and confirming the suitability of this product in their application. To the extent permitted by law, no warranty as to merchantability or fitness of purpose, expressed or implied, is made. Global Headquarters