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Análisis De Duplicidades Terapéuticas

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Análisis De Duplicidades Terapéuticas Direcció General de Farmàcia i Productes Sanitaris ANÁLISIS DUPLICIDAD TERAPÉUTICA SUBRUPO TERAPÉUTICO N06 – PSICOANALÉPTICOS Clasificación ATC N06A – Antidepresivos N06AA: INHIB. NO SELECTIVOS DE LA RECAPTACION MONOAMINAS ANTIDEPRESIVOS TRICICLICOS Y AFINES Maprotilina Trimipramina Amitriptilina Dosulepina Doxepina Clomipramina Imipramina Nortriptilina N06AB: INHIB. SELECTIVOS RECAPTACION SEROTONINA (ISRS) Sertralina Escitalopram Fluoxetina Paroxetina Fluvoxamina Citalopram N06AF: INHIB. NO SELECTIVOS DE LA MONOAMINOXIDASA Tranilcipromina N06AG: INHIB. MONOAMINO-OXIDASA TIPO A (ANTIDEPRESIVOS IMAO A Moclobemida N06AX: OTROS ANTIDEPRESIVOS Mianserina Reboxetina Agomelatina Mirtazapina Bupropion Venlafaxina Duloxetina Oxitriptan Trazodona Desvenlafaxina Tianeptina Vortioxetina Direcció General de Farmàcia i Productes Sanitaris N06B-Psicoestimulantes y Nootrópicos N06BA: SIMPATICOMIMETICOS ACCION CENTRAL Modafinilo Metilfenidato Atomoxetina Dexanfetamina Metilfenidato clorhidrato Lisdexanfemamina N06BC: DERIVADOS DE LAS XANTINAS (PSICOESTIMULANTES) Cafeína N06BX: OTROS PSICOESTIMULANTES Y NOOTROPICOS Vinpocetina Citicolina Pirisudanol Piracetam Hipérico Deanol+Heptaminol G – Aminobutírico ácido + Glutamato magnésico + Piridoxina N06C-Psicolepticos y Psicoanalepticos N06CA: ANTIDEPRESIVOS EN COMBINACION CON PSICOLEPTICOS Perfenacina+Amitriptilina Nortriptilina+Diazepam Amitriptilina+Medazepam Melitraceno+Flupentixol N06D-FARMACOS ANTI-DEMENCIA N06DA: ANTICOLINESTERASAS (MEDICAMENTOS CONTRA DEMENCIA) Donepezilo Galantamina Rivastigmina N06DX: OTROS MEDICAMENTOS ANTI-DEMENCIA Memantina Ginkgo biloba Direcció General de Farmàcia i Productes Sanitaris 1.- Análisis de duplicidades a nivel 4 de la ATC Las presentaciones farmacéuticas de los principios activos existentes en el mercado de los subgrupos terapéuticos N06BX y N06DA son adecuadas para administrar las dosis que se recomiendan en las fichas técnicas, y no requieren de una combinación de varias de ellas. Por tanto, se considera duplicidad, tanto la asociación entre diferentes principios activos de los dos subgrupos terapéuticos como la administración concomitante de dos presentaciones farmacéuticas del mismo principio activo ya que no hay evidencia científica de que la asociación de ambos beneficie al paciente. N06BX N06BX VINPOCETINA VINPOCETINA CITICOLINA CITICOLINA PIRISUDANOL PIRISUDANOL PIRACETAM PIRACETAM + DUPLICIDAD HIPERICO HIPERICO DEANOL+HEPTAMINOL DEANOL+HEPTAMINOL G-AMINOBUTÍRICO ÁCIDO G-AMINOBUTÍRICO + GLUTAMATO ÁCIDO + GLUTAMATO MAGNÉSICO + MAGNÉSICO + PIRIDOXINA PIRIDOXINA En el caso del subgrupo N06DA la asociación es excluyente, es decir, los principios activos de este subgrupo son prácticamente iguales, de modo que solo tiene sentido la prescripción de uno de ellos, por tanto su asociación se considera duplicidad. N06DA N06DA DONEPEZILO DONEPEZILO + DUPLICIDAD GALANTAMINA GALANTAMINA RIVASTIGMINA RIVASTIGMINA A nivel de principio activo se permite asociar presentaciones farmacéuticas diferentes únicamente de la rivastigmina necesarias para alcanzar la dosis terapéutica. La asociación entre diferentes principios activos y la asociación de diferentes presentaciones farmacéuticas del mismo principio activo de los subgrupos terapéuticos N06AA, N06AB, N06AF, N06AG, N06AX, N06BA, N06BC, N06CA y N06DX no se considera duplicidad debido a que puede ser necesaria su asociación para alcanzar las dosis terapéuticas. Direcció General de Farmàcia i Productes Sanitaris N06AA N06AA MAPROTILINA MAPROTILINA TRIMIPRAMINA TRIMIPRAMINA AMITRIPTILINA AMITRIPTILINA + DOSULEPINA DOSULEPINA DOXEPINA DOXEPINA CLOMIPRAMINA CLOMIPRAMINA IMIPRAMINA IMIPRAMINA NORTRIPTILINA NORTRIPTILINA NO6AB NO6AB SERTRALINA SERTRALINA ESCITALOPRAMNO6AF ESCITALOPRAMNO6AF + TRANILCIPROMINAFLUOXETINA TRANILCIPROMINAFLUOXETINA PAROXETINA PAROXETINA FLUVOXAMINA FLUVOXAMINA CITALOPRAM CITALOPRAM NO6AG NO6AG MOCLOBEMIDA + MOCLOBEMIDA NO6AX NO6AX MIANSERINA MIANSERINA REBOXETINA REBOXETINA AGOMELATINA AGOMELATINA MIRTAZAPINA MIRTAZAPINA BUPROPION + BUPROPION VENLAFAXINA VENLAFAXINA DULOXETINA DULOXETINA OXITRIPTAN OXITRIPTAN TRAZODONA TRAZODONA DESVENLAFAXINA DESVENLAFAXINA TIANEPTINA TIANEPTINA VORTIOXETINA VORTIOXETINA Direcció General de Farmàcia i Productes Sanitaris N06BA N06BA MODAFINILO MODAFINILO METILFENIDATO + METILFENIDATO ATOMOXETINA ATOMOXETINA METILFENIDATO METILFENIDATO CLORHIDRATO CLORHIDRATO N06BC N06BC + CAFEINA CAFEINA N06CA + N06CA AMITRIPTLINA+PERFENACINA AMITRIPTLINA+PERFENACINA AMITRIPTILINA+MEDAZEPAM AMITRIPTILINA+MEDAZEPAM NORTRIPTILINA+DIAZEPAM NORTRIPTILINA+DIAZEPAM MELITRACENO+FLUPENTIXOL MELITRACENO+FLUPENTIXOL N06DX N06DX MEMANTINA + MEMANTINA GINKGO BILOBA GINKGO BILOBA 2.- Análisis de duplicidades a nivel 3 de la ATC La asociación entre los principios activos de los subgrupos terapéuticos N06AA, N06AB, 06AF, N06AG y N06AX, no se considera duplicidad. La asociación entre los principios activos de los subgrupos terapéuticos N06BA, N06BC y N06BX, no se considera duplicidad. La asociación entre los principios activos de los subgrupos terapéuticos N06DA y N06DX, no se considera duplicidad. 3.- Análisis de duplicidades a nivel 2 de la ATC La asociación entre los principios activos de los diferentes subgrupos terapéuticos no se considera duplicidad salvo la asociación de los siguientes subgrupos: La asociación entre principios activos de los subgrupos terapéuticos N06AF y N06BA se considera duplicidad debido a que la administración concomitante da lugar a crisis hipertensivas graves. Direcció General de Farmàcia i Productes Sanitaris N06BA NO6AF + MODAFINILO TRANILCIPROMINA METILFENIDATO DUPLICIDAD ATOMOXETINA METILFENIDATO CLORHIDRATO La asociación de un principio activo del subgrupo N06BX con memantina (N06DX) se considera duplicidad debido a que no hay evidencia científica de que dicha asociación beneficie al paciente. Igualmente, la asociación de un principio activo del subgrupo N06BX con ginkgo biloba (N06DX) se considera duplicidad debido a que son muy parecidos y por tanto, no tendría sentido su asociación. N06BX VINPOCETINA CITICOLINA PIRISUDANOL N06DX PIRACETAM MEMANTINA DUPLICIDAD HIPERICO + GINKGO BILOBA DEANOL+HEPTAMINOL G-AMINOBUTÍRICO ÁCIDO + GLUTAMATO MAGNÉSICO + PIRIDOXINA .
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