Subject Index Proc. Natl. Acad. Sci. USA 82 (1985) 8841

A-A-U-A-A-A Region of peptide 125-147 of acetylcholine receptor a subunit is exposed A sequence downstream of A-A-U-A-A-A is required for formation of at neuromuscular junction and induces experimental autoimmune simian virus 40 late mRNA 3' termini in frog oocytes, 3949 myasthenia gravis, T-cell immunity, and modulating autoantibodies, 8805 Abelson murine leukemia virus Phosphorylation of ribosomal protein S6 on serine after microinjection of Acetylcholne receptor, muscarinic the Abelson murine leukemia virus tyrosine-specific protein kinase into Batrachotoxin changes the properties of the muscarinic receptor in rat Xenopus oocytes, 272 brain and heart: Possible interaction(s) between muscarinic receptors and sodium channels, 3524 Acanthanoeba casteUandi Ribosomal RNA transcription: Proteins and DNA sequences involved in Acetylcholine receptor, nicotinic preinitiation complex formation, 1668 Demonstration and affinity labeling of a stereoselective binding site for a Footprinting of ribosomal RNA genes by transcription initiation factor benzomorphan opiate on acetylcholine receptor-rich membranes from and RNA polymerase I, 8004 Torpedo electroplaque, 940 Brain and muscle nicotinic acetylcholine receptors are different but Acanthocyclops vernalis homologous proteins, 5208 Experimental transmission of a microsporidian pathogen from mosquitoes to an alternate copepod host, 5574 Acetyicholineterase Glycyl-L-glutamine, a precursor, and glycyl-L-glutamic acid, a Acceptor site, progesterone receptor neurotrophic factor for maintenance of acetylcholinesterase and Evidence for specific DNA sequences in the nuclear acceptor sites of the butyrylcholinesterase in the preganglionically denervated superior avian oviduct progesterone receptor, 4722 cervical ganglion of the cat in vivo, 5213 Increases in muscle Ca2+ mediate changes in acetylcholinesterase and Accessory cell acetylcholine receptors caused by muscle contraction, 7121 Analysis of antigen presentation by metabolically inactive accessory cells and their isolated membranes, 6647 Acetyicholinesterase gene A human acetylcholinesterase gene identified by homology to the Ace Ace gene region of Drosophila, 1827 A human acetylcholinesterase gene identified by homology to the Ace region of Drosophila, 1827 N-Acetylgalactosamine Blood group A cross-reacting epitope defined by monoclonal antibodies Acetabdaria nediterranea NCC-LU-35 and -81 expressed in cancer of blood group 0 or B Tandemly repeated nonribosomal DNA sequences in the chloroplast individuals: Its identification as Tn antigen, 7039 genome of an Acetabularia mediterranea strain, 1706 Structural requirements for sulfation of asparagine-linked Identification of a high molecular weight polypeptide that may be part of of lutropin, 7850 the circadian clockwork in Acetabularia, 6899 oligosaccharides P-N-Acetyl-D-hex dase 2-Acetylaminofluorene Lysosomotropic agents selectively potentiate thrombin-induced acid Distribution of initial and persistent 2-acetylaminofluorene-induced DNA hydrolase secretion from platelets, 2374 adducts within DNA loops, 6605 ACG initiation codon N-Acetylaspartylglutaimate Direct mapping of adeno-associated virus capsid proteins B and C: A N-Acetylaspartylglutamate: Possible role as the neurotransmitter of the possible ACG initiation codon, 7919 lateral olfactory tract, 3897 Acholeplasmna N-Acetylation Construction of the mycoplasma evolutionary tree from 5S rRNA Analysis of an evolutionarily conserved antigenic site on mammalian sequence data, 1160 cytochrome c using synthetic peptides, 1508 Deposition-related histone acetylation in micronucleus of conjugating Achondroplasia Tetrahymena, 8048 Nonrandom association of a type II procollagen genotype with Amino-terminal processing of proteins: Hemoglobin South Florida, a achondroplasia, 5465 variant with retention of initiator methionine and Na-acetylation, 8448 Acid Acetylcholine See also pH Choline acetyltransferase and acetylcholine in Xenopus oocytes injected Acidic pH requirement for insertion of colicin El into artificial membrane with mRNA from the electric lobe of Torpedo, 608 vesicles: Relevance to the mechanism of action of colicins and certain Is an acetylcholine transport system responsible for nonquantal release of toxins, 1386 acetylcholine at the rodent myoneural junction?, 3514 Changes in 22Na influx and outflux in Daphnia magna (Straus) as a Neurochemical basis for the photic control of circadian rhythms and function of elevated Al concentrations in soft water at low pH, 7345 seasonal reproductive cycles: Role for acetylcholine, 4277 Acetylcholine and phorbol esters inhibit potassium currents evoked by Acid hydrolase adenosine and cAMP in Xenopus oocytes, 6001 Lysosomotropic agents selectively potentiate thrombin-induced acid Two types of muscarinic response to acetylcholine in mammalian cortical hydrolase secretion from platelets, 2374 neurons, 6344 Acquired immunodeficiency syndrome Acetylcholine receptor Immunological properties of the Gag protein p24 of the acquired Use of a replica technique to isolate muscle cell lines defective in immunodeficiency syndrome retrovirus (human T-cell leukemia virus expressing the acetylcholine receptor, 124 type III), 3481 Ascorbic acid mediates acetylcholine receptor increase induced by brain Characterization of a continuous T-cell line susceptible to the cytopathic extract of myogenic cells, 575 effects of the acquired immunodeficiency syndrome (AIDS)-associated Different effects of N-ethylmalemide on Ml and M2 muscarine receptors retrovirus, 4539 in rat brain, 580 Genomic diversity of the acquired immune deficiency syndrome virus Muscarinic cholinergic receptor in the human heart evidenced under HTLV-HII: Different viruses exhibit greatest divergence in their physiological conditions by positron emission tomography, 584 envelope genes, 4813 Topological mapping of acetylcholine receptor: Evidence for a model Monoclonal antibodies specific for p24, the major core protein of human with five transmembrane segments and a cytoplasmic COOH-terminal T-cell leukemia virus type mII, 5199 peptide, 626 Isolation of infectious human T-cell leukemia/lymphotropic virus type III Anomalous interaction of the acetylcholine receptor protein with the (HTLV-III) from patients with acquired immunodeficiency syndrome nonionic detergent Triton X-114, 958 (AIDS) or AIDS-related complex (ARC) and from healthy carriers: A Evidence for unpredicted transmembrane domains in acetylcholine study of risk groups and tissue sources, 5530 receptor subunits, 2004 High prevalence of antibodies to acquired immune deficiency syndrome Myasthenic serum selectively blocks acetylcholine receptors with long (AIDS)-associated retrovirus (ARV) in AIDS and related conditions but channel open times at developing rat endplates, 2533 not in other disease states, 5535 Antibodies to synthetic peptides as probes for the binding site on the a In vitro growth characteristics of simian T-lymphotropic virus type subunit of the acetylcholine receptor, 3490 III, 7053 Activity regulates the levels of acetylcholine receptor a-subunit mRNA in 3'-Azido-3'-deoxythymidine (BW A509U): An antiviral agent that inhibits cultured chicken myotubes, 4558 the infectivity and cytopathic effect of human T-lymphotropic virus Mouse-Torpedo hybrid acetylcholine receptors: Functional homology type III/lymphadenopathy-associated virus in vitro, 7096 does not equal sequence homology, 4852 Bacterial expression of the acquired immunodeficiency syndrome Quantitative in vivo receptor binding III: Tracer kinetic modeling of retrovirus p24 gag protein and its use as a diagnostic reagent, 7748 muscarinic cholinergic receptor binding, 6711 Influence of the human T-lymphotropic virus/lymphadenopathy- Increases in muscle Ca2W mediate changes in acetylcholinesterase and associated virus on functions of human lymphocytes: Evidence for acetylcholine receptors caused by muscle contraction, 7121 immunosuppressive effects and polyclonal B-cell activation by banded The subsynaptic 43-kDa protein is concentrated at developing viral preparations, 8198 nerve-muscle synapses in vitro, 8270 Human T-cell growth factor (interleukin 2) and y-interferon genes: Two molecular weight forms of muscarinic acetylcholine receptors in the Expression in human T-lymphotropic virus type III- and type I-infected avian central nervous system- Switch in predominant form during cells, 8691 differentiation of synapses, 8785 Determination of the primary amino acid sequence specifying the Acrosome a-bungarotoxin binding site on the a subunit of the acetylcholine Calcium channel antagonists inhibit the acrosome reaction and bind to receptor from Torpedo californica, 8790 plasma membranes of sea urchin sperm, 1460 8842 Subject Index Proc. Nadl. Acad. Sci. USA 82 (1985)

Actin Nucleotide sequence and organization of the mouse adenine Calmodulin accelerates the rate of polymerization of human platelet actin phosphoribosyltransferase gene: Presence of a coding region common and alters the structural characteristics of actin filaments, 1683 to animal and bacterial phosphoribosyltransferases that has a variable Cloning of Physarum actin sequences in an exonuclease-deficient intron/exon arrangement, 2731 bacterial host, 2698 A model for actin polymerization and the kinetic effects of ATP Adeno-assodated vir hydrolysis, 7207 Direct mapping of adeno-associated virus capsid proteins B and C: A Exposure of actin thiols by the removal of tightly held calcium ions, 7904 possible ACG initiation codon, 7919 Fraction of myosin cross-bridges bound to actin in active muscle fibers: Adenocarcinoma Estimation by fluorescence anisotropy measurements, 8478 A v-erbB-related protooncogene, c-erbB-2, is distinct from the Actin filament c-erbB-1/epidermal growth factor-receptor gene and is amplified in a Purification and characterization of caldesmon-n: A calmodulin-binding human salivary gland adenocarcinoma, 6497 protein that interacts with actin filaments from bovine adrenal Adenocarcinoma, gastrointestinal medulla, 5025 Characterization of Lewis antigens in normal colon and gastrointestinal Actin gene adenocarcinomas, 3552 All components required for the eventual activation of muscle-specific actin genes are localized in the subequatorial region of an uncleaved Adenosine amphibian egg, 139 Extensive but reversible depletion of ATP via adenylate cyclase in rat Developmentally regulated expression of a chicken muscle-specific gene adipocytes, 1614 in stably transfected rat myogenic cells, 3106 Adenosine-activated potassium conductance in cultured striatal Developmentally regulated expression of a chicken muscle-specific gene neurons, 4857 in stably transfected rat myogenic cells (Correction), 5578 Acetylcholine and phorbol esters inhibit potassium currents evoked by Molecular structure of the human cytoplasmic P-actin gene: Interspecies adenosine and cAMP in Xenopus oocytes, 6001 homology of sequences in the introns, 6133 Adenosine de Identification and order of sequential mutations in P-actin genes isolated Expression of human adenosine deaminase using a transmissable murine from increasingly tumorigenic human fibroblast strains, 6995 retrovirus vector system, 703 Actn-myodn complex Adenosine deaminae binding protein Structure of the actin-myosin complex in the presence of ATP, 3247 Specificity analysis of mouse monoclonal antibodies defining cell surface antiens of human renal cancer, 2955 Actnomycin Specificity analysis of mouse monoclonal antibodies defining cell surface Actinomycin and DNA transcription, 5328 antigens of human renal cancer (Correction), 5236 Activating sequence Adenosine deaminae ddefidency Specific protein binding to far upstream activating sequences in Adenine ribo- and deoxyribonucleotide metabolism in human polymerase II promoters, 43 erythrocytes, B- and T-lymphocyte cell lines, and monocyte- Activation peptide macrophages, 6682 Evidence or a prevalent dimorphism in the activation peptide of human Adenosine 'V-dphosphoribose coagulation factor IX, 2847 Covalent modification of the iron protein of nitrogenase from Activation volume Rhodospirillum rubrum by adenosine diphosphoribosylation of a Cryobaroenzymic studies as a tool for investigating activated complexes: specific arginine residue, 3173 Creatine kinase-ADPMg-nitrate-creatine as a model, 7495 Adenosinetriphosphatase Active site See ATPase See Enzyme active site S-Adenosylhomocyrsteine Active transport 3-Deazaadenosme-induced disorganization of macrophage See also Transport microfilaments, 4060 Protonmotive force-driven active transport of 1-glucose and L-proline in S-Adenosyl-L-homocysteie hydrolase the protozoan parasite Leishmania donovani, 1716 Inactivation of S-adenosyl-L-homocysteine hydrolase by cAMP results Active auxin uptake by zucchini membrane vesicles: Quantitation using from dissociation of enzyme-bound NADI, 4578 ESR volume and ApH determinations, 6541 S-A enosylmethionine Actomyodn subagnt 1 Regulation of methionine synthesis in Escherichia coli: Effect of metJ ADP dissociation from actomyosin subfragment 1 is sufficiently slow to gene product and S-adenosylmethionine on the expression of the metF limit the unloaded shortening velocity in vertebrate muscle, 658 gene, 3601 Acute myelogenous leukemia Stereochemical course of the reaction catalyzed by the pyridoxal Isolation and analysis of the 21q+ chromosome in the acute myelogenous phosphate-dependent enzyme 1-aminocyclopropane-1-carboxylate leukemia 8;21 translocation: Evidence that c-mos is not synthase, 7820 translocated, 464 Adenovirus Transfer of genes into hematopoietic cells using recombinant DNA Acyclovir viruses, 158 Metabolic activation of the nucleoside analog 94[2-hydroxy-1- Evidence that a second tumor antigen coded by adenovirus early gene (hydroxymethyl)ethoxy]methyl}guanine in human diploid fibroblasts region Ela is required for efficient cell transformation, 163 infected with human cytomegalovirus, 2473 An enhancer-like element in the adenovirus E2 promoter contains Potentiation of antiherpetic activity of acyclovir by ribonucleotide sequences essential for uninduced and ElA-induced transcription, 381 reductase inhibition, 4254 Identification of the components necessary for adenovirus translational Acyl carrier protein control and their utilization in cDNA expression vectors, 689 Acyl-acyl carrier protein as a source of fatty acids for bacterial Translational control by adenovirus: Lack of virus-associated RNA, bioluminescence, 6085 during adenovirus infection results in phosphorylation of initiation factor eIF-2 and inhibition of protein synthesis, 1959 Acyl-CoA dehydrogenase Adenovirus EIIA early promoter: Transcriptional control elements and Deficiency of electron transfer flavoprotein or electron transfer induction by the viral pre-early EIA gene, which appears to be flavogrotein:ubiquinone oxidoreductase in glutaric acidemia type II sequence independent, 2230 fibroblasts, 4517 Adenovirus infection elevates levels of cellular topoisomerase I, 2247 Expression in Escherichia coil of a fusion protein product containing a Acl-CoA oxidase region of the adenovirus DNA polymerase, 2354 Cloning of cDNA coding for peroxisomal acyl-CoA oxidase from the The 140-kDA adenovirus DNA polymerase is recognized by antibodies to yeast Candida tropicalis pK233, 3973 Escherichia coli-synthesized determinants predicted from an open reading frame on the adenovirus genome, 2652 ada gene Adenovirus VAI RNA prevents phosphorylation of the eukaryotic Active site and complete sequence of the suicidal methyltransferase that initiation factor 2 a subunit subsequent to infection, 4321 counters alkylation mutagenesis, 2688 Expression of histocompatibility antigens H-2K, -D, and -L is reduced in Adaptive differentiation adenovirus-12-transformed mouse cells and is restored by interferon y, 5525 H-2-incompatible bone marrow chimeras produce donor-H-2-restricted Specific transcription of preformed nucleoprotein complexes, containing Ly-2 suppressor T-cell factor(s), 7063 the adenovirus major late promoter, with a chromatographic fraction Adenine containing RNA polymerase II, 6769 Selective alkylation of carcinogenic 9-anthryloxirane at the N-3 position Mapping of functional domains in adenovirus ElA proteins, 7480 of adenine in DNA, 5250 A first exon-encoded domain of ElA sufficient for posttranslational modification, nuclear-localization, and induction of adenovirus E3 Adenine nudeotide promoter expression in Xenopus oocytes, 8434 Adenine ribo- and deoxyribonucleotide metabolism in human erythrocytes, B- and T-lymphocyte cell lines, and monocyte- Adenovirus vector macrophages, 6682 An adenovirus vector system used to express polyoma virus tumor antigens, 1359 Adenine phosphoribosytrnsfeme gene Overproduction of the protein product of a nonselected foreign gene Effect of regional DNA methylation of gene expression, 2560 carried by an adenovirus vector, 3567 Subject Index Proc. Natl. Acad. Sci. USA 82 (1985) 8843

Expression of hepatitis B surface antigen with a recombinant ADP/ATP translocator adenovirus, 7560 Cloning and expression of the Rickettsia prowazekii ADP/ATP translocator in Escherichia col, 3015 Adenylate cyclase Genetic analysis of S-adrenergic receptor internalization and Adrenal cortex down-regulation, 129 The influence of mevinolin on the adrenal cortical response to Characterization of octopamine-sensitive adenylate cyclase: Elucidation corticotropin in heterozygous familial hypercholesterolemia, 6291 of a class of potent and selective octopamine-2 receptor agonists with toxic effects in insects, 599 Adrenal gland Antisera against a guanine nucleotide binding protein from retina Expression of murine 21-hydroxylase in mouse adrenal glands and in cross-react with the P subunit of the adenylyl cyclase-associated transfected Y1 adrenocortical tumor cells, 7860 guanine nucleotide binding proteins, N, and N., 727 Adrenal hyperplasa Association of the N-formyl-Met-Leu-Phe receptor in human neutrophils Mapping of steroid 21-hydroxylase genes adjacent to complement with a GTP-binding protein sensitive to pertussis toxin, 869 component C4 genes in HLA, the major histocompatibility complex in Extensive but reversible depletion of ATP via adenylate cyclase in rat man, 521 adipocytes, 1614 are located near the cDNA-derived amino acid sequence of the y subunit of GTPase from Two genes encoding steroid 21-hydroxylase genes bovine rod outer segments, 1936 encoding the fourth component of complement in man, 1089 Catalytic unit of adenylate cyclase: Purification and identification by Adrenal medulla affinity crosslinking, 3086 t-Aminobutyric acid receptor channels in adrenal chromaffin cells: A On ras gene function in yeast, 4740 patch-clamp study, 2168 Isolation of the gene encoding adenylate cyclase in Saccharomyces cerevisiae, 5060 Adrenergic agent Genetic dissection of Drosophila adenylate cyclase, 5992 Adrenergic regulation of gluconeogenesis: Possible involvement of two Reconstitution of the GTP-dependent adenylate cyclase from products of mechanisms of signal transduction in ai-adrenergic action, 6727 the yeast CYRI and RAS2 genes in Escherichia coli, 7855 Reconstitution of regulatory properties of adenylate cyclase in Adrenergic antagonlat Escherichia coli extracts, 8300 (-)-S-[3H]CGP-12177 and its use to determine the rate constants of unlabeled P-adrenergic antagonists, 925 Adenylate cyclase catalytic subunit Identification of the catalytic subunit of brain adenylate cyclase: A Adrenerplc receptor calmodulin binding protein of 135 kDa, 6736 Genetic analysis of -adrenergic receptor internalization and down-regulation, 129 Adenylate cyclase gene (3-Adrenergic agonist activity of a monoclonal anti-idiotypic Translational efficiency of the Escherichia coli adenylate cyclase gene: antibody, 1781 Mutating the UUG initiation codon to GUG or AUG results in P2-Adrenergic receptors contribute to catecholamine-stimulated increased gene expression, 5656 shortening of action potential duration in dog atrial muscle, 4521 Molecular comparison of a,- and a2-adrenergic receptors suggests that Adenylate kinase these proteins are structurally related "isoreceptors", 4842 Locating a nucleotide-binding site in the thymidine kinase of vaccinia Structural similarities between the mammalian P-adrenergic and reovirus virus and of herpes simplex virus by scoring triply aligned protein type 3 receptors, 5315 sequences, 6815 Prazosin, an a1-adrenergic receptor antagonist, suppresses experimental autoimmune encephalomyelitis in the Lewis rat, 5915 Adenylylated enzyme Do agonists promote rapid internalization of P-adrenergic Cyclization of RNA 3'-terminal phosphate by cyclase from HeLa cells receptors?, 6566 proceeds via formation of N(3')pp(5')A activated intermediate, 1316 Blockade of P- but not of 2-adrenergic receptors replicates propranolol's suppression of the cerebral spread of an engram in Adhi gene mice, 7458 Insertion of an unstable element in an intervening sequence of maize Thyrotropin upregulates a1-adrenergic receptors in rat FRTL-5 thyroid Adhl affects transcription but not processing, 2875 cells, 8677 Adhesin Adrenergic receptor phosphorylation Adhesion to human cells by Escherichia coli lacking the major subunit of Phorbol esters promote aL-adrenergic receptor phosphorylation and a digalactoside-specific pilus-adhesin, 1800 receptor uncoupling from inositol phospholipid metabolism, 5651 Adhesion, bacterial Adrenergic response Antibodies to peptides corresponding to a conserved sequence of Rat Sertoli cells acquire-a P-adrenergic response during primary gonococcal pilins block bacterial adhesion, 915 culture, 2049 Adhesion, cellular Adrenoceptor Phosphotyrosine-containing proteins are concentrated in focal adhesions External Ca-independent release of noradrenaline by sympathomimetics and intercellular junctions in normal cells, 6576 and its role in negative feedback modulation, 8775 Adhesion sequence Adrenocortlcotropin A 125/115-kDA cell surface receptor specific for vitronectin interacts NH2-terminal specificity and axonal localization of adrenocorticotropin with the arginine-glycine-aspartic acid adhesion sequence derived from binding sites in rat median eminence, 1271 5766 fibronectin, Adrenodoxin Adipocyte Molecular cloning and amino acid sequence of the precursor form of Molecular approach to thermogenesis in brown adipose tissue: cDNA bovine adrenodoxin: Evidence for a previously unidentified cloning of the mitochondrial uncoupling protein, 445 COOH-terminal peptide, 5705 Extensive but reversible depletion of ATP via adenylate cyclase in rat adipocytes, 1614 Adult T-cell leukemia A developmentally regulated mRNA from 3T3 adipocytes encodes a p27X-m and p21X-IU proteins encoded by the pX sequence of human novel serine protease homologue, 6480 T-cell leukemia virus type I, 8359 Growth hormone and insulin-like growth factors I and II produce distinct Advanced glycosylatIon end product alterations in glucose metabolism in 3T3-F442A adipocytes, 8724 High-affinity-receptor-mediated uptake and degradation of glucose-modified proteins: A potential mechanism for the removal of Adipogenic differentiation senescent macromolecules, 5588 Type P transforming growth factor controls the adipogenic differentiation High-affinity-receptor-mediated uptake and degradation of of 3T3 fibroblasts, 8530 glucose-modified proteins: A potential mechanism for the removal of Adolescence senescent macromolecules (Correction), 8274 Adolescence in Tetrahymena thermophila, 436 Aedes cantator ADP Experimental transmission of a microsporidian pathogen from mosquitoes ADP dissociation from actomyosin subfragment 1 is sufficiently slow to to an alternate copepod host, 5574 limit the unloaded shortening velocity in vertebrate muscle, 658 Aeguorin CAe entry in squid axons during voltage-clamp pulses is mainly ADP-ribose Na+/Ca2+ exchange, 1847 Effects of phospholipids and ADP-ribosylation on GTP hydrolysis by Cloning and sequence analysis of cDNA for the luminescent protein Escherichia coli-synthesized Ha-ras encoded p21, 8310 aequorin, 3154 ADP-ribose-L-arginine cleavage enzyme Aerobic grow Reversibility of arginine-specific mono(ADP-ribosyl)ation: Identification Mechanisms determining aerobic or anaerobic growth in the facultative in erythrocytes of an ADP-ribose-L-arginine cleavage enzyme, 5603 anaerobe Salmonella typhimurium, 2077 ADP-ribosylation Affinity chromatography Pertussis toxin inhibition of chemotaxis and the ADP-ribosylation of a Rapid purification of cytosolic epoxide hydrolase from normal and membrane protein in a human-mouse hybrid cell line, 2637 clofibrate-treated animals by affinity chromatography, 1663 Reversibility of arginine-specific mono(ADP-ribosyl)ation: Identification Catalytic unit of adenylate cyclase: Purification and identification by in erythrocytes of an ADP-ribose-L-arginine cleavage enzyme, 5603 affinity crosslinking, 3086 8844 Subject Index Proc. Natl. Acad. Sci. USA 82 (1985)

Immunoaffinity purification of factor IX (Christmas factor) by using Alcoholism conformation-specific antibodies directed against the factor IX-metal Abnormal polyunsaturated fatty acid patterns of serum lipids in complex, 3879 alcoholism and cirrhosis: Arachidonic acid deficiency in cirrhosis, 1815 Toward an analogue of alcoholism in mice: Criteria for recognition of Aflatoxin pharmacologically motivated drinking, 3469 Sequence context effects in DNA replication blocks induced by aflatoxin B1, 3096 Aldhyde dehydrogena Aflatoxin metabolism in humans: Detection of metabolites and nucleic Cloning of cDNAs for human aldehyde dehydrogenases 1 and 2, 3771 acid adducts in urine by affinity chromatography, 6492 Aldolm Afterhyperpolarizaton A lethal deletion on mouse chromosome 7 affects regulation of in ganglion liver-cell-specific functions: Posttranscriptional control of serum Two distinct Ca-dependent K currents bullfrog sympathetic protein and transcriptional control of aldolase B synthesis, 2442 cells, 3040 Identification of intracellular degradation intermediates of aldolase B by Aggrssion antiserum to the denatured enzyme, 6114 ~Synthetic pheromones that promote inter-male aggression in mice, 2059 Aldose reductase Kin discrimination by worker honey bees in genetically mixed Activated and unactivated forms of human erythrocyte aldose groups, 3058 reductase, 7222 Aging Aleurain Peroxide-producing potential of tissues: Inverse correlation with mammalian longevity of mammalian species, 4798 Aleurain: A barley thiol protease closely related to cathepsin High-affimty-receptor-mediated uptake and degradation of H, 6512 glucose-modified proteins: A potential mechanism for the removal of Alp senescent macromolecules, 5588 Ochromonas mitochondria contain a specific chloroplast protein, 1456 Disulfide bond formation in the eye lens, 7965 High-affinity-receptor-mediated uptake and degradation of Alkaline - glucose-modified proteins: A potential mechanism for the removal of ATP is essential for protein translocation into Escherichia coli membrane senescent macromolecules (Correction), 8274 vesicles, 4384 Fusions of secreted proteins to alkaline phosphatase: An approach for Agrobacteriuw wnfaciens studying protein secretion, 5107 Identification of pTiC58 plasmid-encoded proteins for virulence in Human placental alkaline phosphatase in liver and intestine, 6080 Agrobacterium tumefaciens, 2669 TnphoA: A transposon probe for protein export signals, 8129 Mitochondrial origins, 4443 T-DNA border sequences required for crown gall tumorigenesis, 5112 AlHkline phopat gene Nucleotide sequences of the Pseudomonas savastanoi indoleacetic acid Two alkaline phosphatase genes positioned in tandem in Bacillus genes show homology with Agrobacterium tumefaciens T-DNA, 6522 lichen formis MC14 require different RNA polymerase holoenzymes for transcription, 1035 AIDS Cloning, sequencing, and chromosomal localization of human term See Acquired immunodeficiency syndrome placental alkaline phosphatase cDNA, 8715 AIDS-associated retrovhrus AlkylatN agent High prevalence of antibodies to acquired immune deficiency syndrome Alkylating agent resistance: In vitro studies with human cell lines, 2158 (AIDS)-associated retrovirus (ARV) in AIDS and related conditions but not in other disease states, 5535 Alkylaton muags Active site and complete sequence of the suicidal methyltransferase that AIDS-related complex counters alkylation mutagenesis, 2688 Isolation of infectious human T-cell leukemia/lymphotropic virus type III (HTLV-III) from patients with acquired immunodeficiency syndrome O'-Alkylgpuaine-DNA alkyltrasawe (AIDS) or AIDS-related complex (ARC) and from healthy carriers: A 06-Alkylguanine-DNA alkyltransferase activity correlates with the therapeutic response of human rhabdomyosarcoma xenografts to study of risk groups and tissue sources, 5530 142-chloroethyl)-34trans-4-methylcyclohexyl)-1-nitrosourea, 2985 Alanine rat brain semiselective pulses, 3115 Allelic exclusion 'H homonuclear editing of using Low frequency of somatic mutation in a-chain variable region genes of Albinism humanlT-cell receptors, 7701 Calcium binding in pigmented and albino eyes, 6716 Allodeterminant Albino locus Alloreactive cytolytic T-cell clones preferentially recognize Deletions near the albino locus on chromosome 7 of the mouse affect the conformational determinants on histocompatibility antigens: Analysis level of tyrosine aminotransferase mRNA, 2866 with genetically engineered hybrid antigens, 7030 Albumin Allophycocyanin Expression of the mouse serum albumin gene introduced into Molecular cloning and nucleotide sequence of the a and 8 subunits of differentiated and dedifferentiated rat hepatoma cells, 765 allophycocyanin from the cyanelle genome of Cyanophora Dissociation from albumin: A potentially rate-limiting step in the paradoxa, 3242 clearance of substances by the liver, 1563 Ailotype Maintenance of differentiated rat hepatocytes in primary culture, 3252 Suppression of IgE secretion from hybridoma cells in allotype cogenic A frameshift mutation of the pre-S region of the human hepatitis B virus mice: Suppression of allotype 7a by T cells in allotype b mice, 8134 genome allows production of surface antigen particles but eliminates binding to polymerized albumin, 3440 N-Allyl-N-normetazocne Human group-specific component (Gc) is a member of the albumin Demonstration and affinity labeling of a stereoselective binding site for a family, 7994 benzomorphan opiate on acetylcholine receptor-rich membranes from Torpedo electropaque, 940 Albumin, maleylated Scavenger receptor-mediated recognition of maleyl bovine plasma a gene albumin and the demaleylated protein in human monocyte Nucleotide sequence and predicted amino acid sequence of a protein macrophages, 2693 encoded in a small herpes simplex virus DNA fragment capable of trans-inducing a genes, 5870 Alcaligenes eutrohus Genes specifying degradation of 3-chlorobenzoic acid in plasmids pAC27 a pheromone and pJP4, 1638 Control of yeast a-specific genes: Evidence for two blocks to expression in MATa/MATa diploids, 5855 Alcohol dehydrogenase Cloning and sequencing of cDNA encoding the complete mouse liver Alprenolol alcohol dehydrogenase, 2262 (-)-S-[3H]CGP-12177 and its use to determine the rate constants of Molecular cloning of a full-length cDNA for human alcohol unlabeled P-adrenergic antagonists, 925 dehydrogenase, 2703 Altriam Insertion of an unstable element in an intervening sequence of maize Gene-culture coevolution: Models for the evolution of altruism with Adhi affects transcription but not processing, 2875 cultural 5814 Human class I alcohol dehydrogenases catalyze the oxidation of glycols transmission, in the metabolism of norepinephrine, 4979 Ala sequence Molecular cloning of a full-length cDNA for human alcohol Nucdeotide sequence and structure of the human apolipoprotein E dehydrogenase (Correction), 5578 gene, 3445 X-ADH is the sole alcohol dehydrogenase isozyme of mammalian brains: Isolation of the human insulin-like growth factor genes: Insulin-like Implications and inferences, 8369 growth factor H and insulin genes are contiguous, 6450 Polymorphism and evolution of Alu sequences in the human low density Alcohol oxidation lipoprotein receptor gene, 7651 Immunochemical evidence for induction of the alcohol-oxidizing cytochrome P450 of rabbit liver microsomes by diverse agents: Aluwmiu Ethanol, imidazole, trichloroethylene, acetone, pyrazole, and Changes in 2Na influx and outflux in Daphnia magna (Straus) as a isoniazid, 4065 function of elevated Al concentrations in soft water at low pH, 7345 Subject Index Proc. Natl. Acad. Sci. USA 82 (1985) 8845

Alzheimer disease Ammonium chloride Paired helical filaments from Alzheimer disease patients contain Lysosomotropic agents selectively potentiate thrombin-induced acid cytoskeletal components, 3916 hydrolase secretion from platelets, 2374 Amyloid plaque core protein in Alzheimer disease and Down syndrome, 4245 Amnion Aberrant neurofilament phosphorylation in Alzheimer disease, 4274 Invasiveness and ploidy of human mammary carcinomas in short-term Anatomical correlates of the distribution of the pathological changes in culture, 1805 the neocortex in Alzheimer disease, 4531 Cholinergic ventral forebrain grafts into the neocortex improve passive Amphetamine avoidance memory in a rat model of Alzheimer disease, 5227 Glucostatic regulation of (+)-[3H]amphetamine binding in the Dissociated cell culture of cholinergic neurons from nucleus basalis of hypothalamus: Correlation with Na+,K+-ATPase activity, 6320 Meynert and other basal forebrain nuclei, 6325 Amphibian egg Neuritic plaques and cerebrovascular amyloid in Alzheimer disease are All components required for the eventual activation of muscle-specific antigenically related, 8729 actin genes are localized in the subequatorial region of an uncleaved a-Amanitin amphibian egg, 139 a-Amanitin resistance is developmentally regulated in carrot, 2799 Amphipathicity Amber termination codon T-cell antigenic sites tend to be amphipathic structures, 7048 Hypermutation at the immunoglobulin heavy chain locus in a pre-B-cell line, 479 Amplicon Murine leukemia virus protease is encoded by the gag-pol gene and is The herpes simplex virus amplicon: Analyses of cis-acting replication synthesized through suppression of an amber termination codon, 1618 functions, 694 Amblyospora ampR gene Experimental transmission of a microsporidian pathogen from mosquitoes Regulatory components in Citrobacterfreundii ampC p-lactamase to an alternate copepod host, 5574 induction, 4620 Ambystoma ligrinum Amylase gene Synaptic transmission of rods to bipolar cells in the tiger salamander A 78-kilobase region of mouse chromosome 3 contains salivary and retina, 3944 pancreatic amylase genes and a pseudogene, 5446 Amino acid Amyloid. Induction of ornithine decarboxylase activity by insulin and growth Neuritic plaques and cerebrovascular amyloid in Alzheimer disease are factors is mediated by amino acids, 4365 antigenically related, 8729 Induction of ornithine decarboxylase activity by insulin and growth Amyloid plaque core protein factors is mediated by amino acids (Correction), 8274 Amyloid plaque core protein in Alzheimer disease and Down Amino acid control, general syndrome, 4245 A synthetic HIS4 regulatory element confers general amino acid control on the cytochrome c gene (CYC1) of yeast, 498 Amyloidosis Complete primary structures of two major murine serum amyloid A Amino acid sequence comparison proteins deduced from cDNA sequences, 2915 Multiple-alphabet amino acid sequence comparisons of the immunoglobulin K-chain constant domain, 8597 Anabaena Pathway of assembly of ribulosebisphosphate carboxylase/oxygenase Amino acid sequencing from Anabaena 7120 expressed in Escherichia coli, 6546 Peptide mixture sequencing by tandem Fourier-transform mass spectrometry, 6367 Anacysts nidulans Expression and assembly of active cyanobacterial ribulose-1,5- Amino acid substitution, neutral bisphosphate carboxylase/oxygenase in Escherichia coli containing Detection of neutral amino acid substitutions in proteins, 7646 stoichiometric amounts of large and small subunits, 6100 the Amino acid uptake Organization of pigment proteins in the photosystem II complex of Stimulation of glycolysis and amino acid uptake in NRK49F cells by cyanobacterium Anacystis nidulans R2, 6903 transforming growth factor , and epidermal growth factor, 1350 Anaerobiosis 2-Amino-2'-deoxyadenosine Molybdate reduction by Escherichia coli K-12 and its chl mutants, 227 Modified oligonucleotides as alternatives to the synthesis of mixed Mechanisms determining aerobic or anaerobic growth in the facultative 7510 anaerobe Salmonella typhimurium, 2077 probes for the screening of cDNA libraries, Molybdate reduction by Escherichia coli K-12 and its chl mutants Aminoacyl site (Correction), 3532 A second tRNA binding site on elongation factor Tu is induced while the factor is bound to the ribosome, 3212 Anaeroplasma Construction of the mycoplasma evolutionary tree from 5S rRNA Aminoacyl-tRNA synthetase sequence data, 1160 Covalent enzyme-RNA complex: A tRNA modification that prevents a covalent enzyme interaction also prevents aminoacylation, 339 Analgesia ,B-Endorphin-(1-27) is a naturally occurring antagonist to Aminoacylation etorphine-induced analgesia, 3178 Deletions in the 3-terminal tRNA-like structure of brome mosaic virus RNA differentially affect aminoacylation and replication in vitro, 5636 Anaphylatoxin Cardiac caused human C3a 886 3-Aminobenzamide dysfunction by purified anaphylatoxin, Accumulation of 10-kilobase DNA replication intermediates in cells Ana h buds, intestinal treated with 3-aminobenzamide, 104 Depletion of mucosal mast cell protease by corticosteroids: Effect on rAminobutyric acid intestinal anaphylaxis in the rat, 1214 An arylaminopyridazine derivative of y-aminobutyric acid (GABA) is a Anchorage-independent growth selective and competitive antagonist at the GABAA receptor site, 1832 Type B transforming growth factor: A bifunctional regulator of cellular r-Aminobutyric acid receptor growth, 119 GABAB-receptor-activated K+ current in voltage-clamped CA3 pyramidal Evidence that a second tumor antigen coded by adenovirus early gene cells in hippocampal cultures, 1558 region Ela is required for efficient cell transformation, 163 An arylaminopyridazine derivative of y-aminobutyric acid (GABA) is a Identification of a single chromosome in the normal human genome selective and competitive antagonist at the GABAA receptor site, 1832 essential for suppression of hamster cell transformation, 570 y-Aminobutyric acid receptor channels in adrenal chromaffin cells: A Transformation of human cells by DNAs ineffective in transformation of patch-clamp study, 2168 NIH 3T3 cells, 2399 Monoclonal antibodies reveal structural homogeneity of -aminobutyric Androgen acid/benzodiazepine receptors in different brain areas, 4837 rat 2728 Benzodiazepine/y-aminobutyric acid receptor deficit in the midbrain of 19-Hydroxylation of androgens in the brain, the seizure-susceptible gerbil, 6701 Androgen-binding protein 1-Aminocydopropane-1-carboxylate synthase Testicular peritubular cells secrete a protein under androgen control that Stereochemical course of the reaction catalyzed by the pyridoxal modulates Sertoli cell functions, 114 phosphate-dependent enzyme 1-aminocyclopropane-1-carboxylate Androgen receptor synthase, 7820 Autoimmune anti-androgen-receptor antibodies in human serum, 8345 8Aminolevulinate synthase Isolation of recombinant cDNAs encoding chicken erythroid Anemia &-aminolevulinate synthase, 3702 Interferon is a mediator of hematopoietic suppression in aplastic anemia in vitro and possibly in vivo, 188 Aminopeptidase, tripepddyl Mammalian reticulocytes lose adhesion to fibronectin during maturation Novel activity of human angiotensin I converting enzyme: Release of the to erythrocytes, 440 NH2- and COOH-terminal tripeptides from the luteinizing Differentiation of normal marrow and HL60 cells induced by hormone-releasing hormone, 1025 antithymocyte globulin, 4823 8846 Subject Index Pr,oc. Nati. Acad. Sci. USA 82 (1985)

Aneuploidy Enhancement of antibody response by mouse dendritic cells pulsed with Asbestos-associated chromosomal changes in human mesothelial tobacco mosaic virus or with rabbit antiidiotypic antibodies raised cells, 3884 against a private rabbit idiotype, 8149 Heteroantibody duplexes target cells for lysis by cytotoxic T Anglogenesis 8648 Pure brain-derived acidic fibroblast growth factor is a potent angiogenic lymphocytes, vascular endothelial cell mitogen with sequence homology to Anti-Immunogobuln interleukin 1, 6409 B-cell growth factor (B-cell growth factor I or B-cell-stimulating factor, Primary structure of bovine pituitary basic fibroblast growth factor (FGF) provisional 1) is a differentiation factor for resting B cells and may not and comparison with the amino-terminal sequence of bovine brain induce cell growth, 2465 acidic FGF, 6507 Antibiotic resistance Angiosperm Efficient induction and selection of chloroplast-encoded Preferential fertilization in Plumbago: Ultrastructural evidence for antibiotic-resistant mutants in Nicotiana, 1485 gamete-level recognition in an angiosperm, 6129 Antibody Angiotensin See also Monoclonal antibody Atrial natriuretic factor inhibits dehydration- and angiotensin II-induced Small peptides induce antibodies with a sequence and structural water intake in the conscious unrestrained rat, 8720 requirement for binding antigen comparable to antibodies raised against Angiotensin I converting enzyme the native protein, 178 Novel activity of human angiotensin I converting enzyme: Release of the Antibody, conformation-specific NH2- and COOH-terminal tripeptides from the luteinizing Immunoaffinity purification of factor IX (Christmas factor) by using hormone-releasing hormone, 1025 conformation-specific antibodies directed against the factor IX-metal Angiotensin II complex, 3879 Studies on angiotensin II and analogs: Impact of substitution in position 8 Antibody, neutralizing on conformation and activity, 1881 Synthetic peptides from four separate regions of the poliovirus type 1 Increased angiotensin II binding affinity in the nucleus tractus solitarius capsid protein VP1 induce neutralizing antibodies, 910 of spontaneously hypertensive rats, 7721 Antibody Angiotensin I receptor Productionproductionof antibody associated with non-A, non-B hepatitis in a Angiotensin IT receptor binding sites in brain microvessels, 6340 chimpanzee lymphoblastoid cell line established by in vitro Anglerfish transformation with Epstein-Barr virus, 2138 Processing of an anglerfish somatostatin precursor to a Efficient generation of antibodies to oncoproteins by using synthetic hydroxylysine-containing somatostatin 28, 277 peptide antigens, 3400 2,5-Anhydromannitol Antibody response Inhibition by 2,5-anhydromannitol of glyrolysis in isolated rat Enhancement of antibody response by mouse dendritic cells pulsed with hepatocytes and in Ehrlich ascites cells, 78 tobacco mosaic virus or with rabbit antiidiotypic antibodies raised against a private rabbit idiotype, 8149 Aniridia Molecular analysis of chromosome 11 deletions in aniridia-Wllms tumor Anticarcinogen syndrome, 8592 Nanomolar concentrations of Bowman-Birk soybean protease inhibitor suppress x-ray-induced transformation in vitro, 5395 Annulation Total synthesis of (+)-lla-hydroxyprogesterone by cyclization of a Antifreeze protein gene polyunsaturated epoxide, 1879 Antifreeze protein genes are tandemly linked and clustered in the genome of the winter flounder, 2613 Ant Preimaginal learning as a basis of colony-brood recognition in the ant Antigen-antibody interaction Cataglyphis cursor, 8545 General method for the rapid solid-phase synthesis of large numbers of Size and behavior in ants: Constraints on complexity, 8548 peptides: Specificity of antigen-antibody interaction at the level of individual amino acids, 5131 Antamanide Lithium perhydroantamanide complex (2:1): Exposure of the peptide Antigen-bin site backbone in the analog of antamanide with antitoxic impotency, 7155 Antigen-binding specificities of antibodies are primarily determined by seven rpsidues of VH, 2945 Antenna, photosynthetic Structural invariants of antigen binding: Comparison of immunoglobulin Light-harvesting II (B800-B850 complex) structural genes from VL-VH and VL-VL domain dimers, 4592 Rhodopseudomonas capsulata, 58 Antigen, mycobacterial Antenna protein Dissection of Mycobacterium tuberculosis antigens using recombinant Gene expression of pigment-binding proteins of the bacterial DNA, 2583 photosynthetic apparatus: Transcription and assembly in the membrane of Rhodopseudomonas capsulata, 6485 Antigen presentation Organization of pigment proteins in the photosystem II complex of the The /3 domain of the mouse En chain is important for restricted antigen cyanobacterium Anacystis nidulans R2, 6903 presentation to helper T-cell hybridomas, 1678 T-cell activation by peptide antigen: Effect of peptide sequence and Antheraea polyphemnus method of antigen presentation, 5480 Nucleotide sequence of an unusual regionally expressed silkmoth chorion Analysis of antigen presentation by metabolically inactive accessory cells RNA: Predicted primary and secondary structures of an architectural and their isolated membranes, 6647 protein, 6035 Kinetic properties of a sex pheromone-degrading enzyme: The sensillar Antigen-presenpfig cell esterase of Antheraea polyphemus, 8827 Ia-transfected L-cell fibroblasts present a lysozyme peptide but not a native protein to lysozyme-specific T cells, 5885 Anthocyanin Anti-immunoglobulin augments the B-cell antigen-presentation function Mode of coaction between blue/UV light and light absorbed by independently of internalization of receptor-antigen complex, 5890 phytochrome in light-mediated anthocyanin formation in the milo Bone marrow-derived thymic antigen-presenting cells determine (Sorghum vulgare Pers.) seedling, 6124 self-recognition of Ia-restricted T lymphocytes, 5900 9-Anthryloxirane Antigen processing Selective alkylation of carcinogenic 9-anthryloxirane at the N-3 position Intracellular class II HLA antigens are accessible to transferrin- of adenine in DNA, 5250 neuraminidase conjugates internalized by receptor-mediated endocytosis, 8188 Anti-DNA antibody Immunization of rabbits with purified RNA polymerase I induces a Antigen receptor, T-cell distinct population of antibodies against nucleic acids as well as A 20-kDa protein associated with the murine T-cell antigen receptor is anti-RNA polymerase I antibodies, both characteristic of systemic phosphorylated in response to activation by antigen or concanavalin lupus erythematosus, 6797 A, 1%96 Assignment of the gene coding for the T3-8 subunit of the T3-T-cell Anti-idiotypic antibody receptor complex to the long arm of human chromosome 11 and to Isolation and biochemical characterization bf the mammalian reovirus mouse chromosome 9, 2920 type 3 cell-surface receptor, 1494 Regulation of T-cell receptor gene expression in human T-cell /3-Adrenergic agonist activity of a monoclonal anti-idiotypic development, 4503 antibody, 1781 Gene repertoire of the anti-poly(Glu6wAla3nTyrlO) (GAT) immune Antigen recognition response: Comparison of VH, VK, and D regions used by anti-GAT Analysis of cDNA clones specific for human T cells and the a and P antibodies and monoclonal antibodies produced after anti-idiotypic chains of the T-cell receptor heterodimer from a human T-cell immunization, 4788 line, 3430 Monoclonal antiidiotypic antibodies related to a murine oncofetal bladder Isolation of cDNA clones encoding a T-cell receptor P-chain from a beef tumor antigen induce specific cell-mediated tumor immunity, 6286 insulin-specific hybridoma, 8163 Use of anti-idiotypic antibodies to identify a receptor for the T-cell I-J Rearrangement and expression of the a- and /3-chain genes of the T-cell determinant, 7399 antigen receptor in functional murine suppressor T-cell clones, 8638 Subject Index Prooc. Nadl. Acad. Sci. USA 82 (1985) 8847

Antigen, surface Apis mellfera Selective enhancement of the expression of granulocyte functional Kin discrimination by worker honey bees in genetically mixed antigens 1 and 2 on human neutrophils, 2503 groups, 3058 Expression of Plasmodium falciparum surface antigens in Escherichia Flower petal microtexture is a tactile cue for bees, 4750 coli, 2518 Aplysia cafornca Antigen, synthetic peptide Associative conditioning analog selectively increases cAMP levels of tail Small peptides induce antibodies with a sequence and structural sensory neurons in Aplysia, 2548 requirement for binding antigen comparable to antibodies raised against The small cardioactive peptides A and B of Aplysia are derived from a the native protein, 178 common precursor molecule, 3925 Monosynaptic connections made by the sensory neurons of the gill- and Antigenic determinant in the of Recognition of interspecies hybrid class I histocompatibility antigens by siphon-withdrawal reflex in Aplysia participate storage antigen-specific cytolytic T lymphocytes, 6276 long-term memory for sensitization, 8266 Antigenic determinant, confornatoal Apolipoprotein Alloreactive cytolytic T-cell clones preferentially recognize Comparative analysis of repeated sequences in rat apolipoproteins A-I, conformational determinants on histocompatibility antigens: Analysis A-IV, and E, 992 with genetically engineered hybrid antigens, 7030 Apolipoprotein A-I Apolipoprotein E mRNA is abundant in the brain and adrenals, as well Antigenic site, conserved as in the liver, and is present in other peripheral tissues of rats and Analysis of an evolutionarily conserved antigenic site on mammalian marmosets, 203 cytochrome c using synthetic peptides, 1508 Proapolpoprotein A-I conversion kinetics in vivo in human and in Antigenic variant rat, 874 Selection of unique antigenic variants of Newcastle disease virus with Expression of rat apolipoprotein A-IV and A-I genes: mRNA induction neutralizing monoclonal antibodies and anti-immunoglobulin, 7106 during development and in response to glucocorticoids and insulin, 8242 Antigenic variation Sequence variation in the gene for the immunogenic capsid protein VP1 Apolipoprotein A-IV of foot-and-mouth disease virus type A, 2618 Apolipoprotein multigene family: Tandem organization of human Rapid processing of the carboxyl terminus of a trypanosome variant apolipoprotein Al, CIII, and AIV genes, 6374 surface glycoprotein, 3207 Expression of rat apolipoprotein A-IV and A-I genes: mRNA induction during development and in response to glucocorticoids and Antigenicity insulin, 8242 Efficient generation of antibodies to oncoproteins by using synthetic peptide antigens, 3400 Apolipoprotein B Cloning and expression of apolipoprotein B, the major protein of low and Antlunutator very low density lipoproteins, 4597 Mutagenic DNA repair in Streptomyces, 1180 A partial cDNA clone for human apoliprotein B, 4983 Antioxidant Human apolipoprotein B cDNA clone isolation and demonstration that Peroxide-producing potential of tissues: Inverse correlation with liver apolipoprotein B mRNA is 22 kilobases in length, 6825 longevity of mammalian species, 4798 Molecular cloning and expression of partial cDNAs and deduced amino On the mechanisms of induction of cancer-protective enzymes: A acid sequence of a carboxyl-terminal fragment of human apolipoprotein unifying proposal, 8232 B-100, 7265 Antiport Apolipoprotein B-100 Characterization of the activation of Na+/H+ exchange in lymphocytes Human apolipoprotein B-100: Cloning, analysis of liver mRNA, and by phorbol esters: Change in cytoplasmic pH dependence of the assignment of the gene to chromosome 2, 8340 antiport, 1429 Apolipoprotein E Antipyrylazo III Apolipoprotein E mRNA is abundant in the brain and adrenals, as well of in 1864 as in the liver, and is present in other peripheral tissues of rats and Optical measurement voltage-dependent Ca2+ influx frog heart, marmosets, 203 Antireceptor antibody Evolution of apolipoprotein E: Mouse sequence and evidence for an IgM RNA switch from membrane to secretory form is prevented by 11-nucleotide ancestral unit, 8085 adding antireceptor antibody to bacterial lipopolysaccharide-stimulated Human apolipoprotein E expression in Escherichia coli: Structural and murine primary B-cell cultures, 7384 functional identity of the bacterially produced protein with plasma apolipoprotein E, 8696 Antisense RNA A cH-dependent promoter is located within the Q gene of bacteriophage Apolipoprotein E gene X, 3134 Nucleotide sequence and structure of the human apolipoprotein E gene, 3445 Antitermination Defective antitermination of rRNA transcription and derepression of Apolipoprotein gene rRNA and tRNA synthesis in the nusBS mutant of Escherichia Apolipoprotem multigene family: Tandem organization of human coli, 5275 apolipoprotein AI, CIII, and AIV genes, 6374 globulin Apurinic site AntithymocyteDifferentiation of normal marrow and HL60 cells induced by Endonuclease HI (nth) mutants of Escherichia coli, 474 antithymocyte globulin, 4823 Apyrmidink site a,-Antidypsn Endonuclease-resistant apyrimidinic sites formed by neocarzinostatin at Expression of the a1-proteinase inhibitor gene in human monocytes and cytosine residues in DNA: Evidence for a possible role in macrophages, 795 mutagenesis, 3182 The cellular defect in ac-proteinase inhibitor (a1-PI) deficiency is expressed in human monocytes and in Xenopus oocytes injected with wra gene human liver mRNA, 6918 A dimer of AraC protein contacts three adjacent major groove regions of the aral DNA site, 3129 Antitumor activity Strong antitumor activities of IgG3 antibodies to a human AraC protein melanoma-associated ganglioside, 1499 A dimer of AraC protein contacts three adjacent major groove regions of the aral DNA site, 3129 Antitumor drug Alkylating agent resistance: In vitro studies with human cell lines, 2158 Arachidonic add Glucose increases the synthesis of lipoxygenase-mediated metabolites of Antiviral drug arachidonic acid in intact rat islets, 198 Sequence and mapping analyses of the herpes simplex virus DNA Inhibition of human platelet phospholipase A2 activity by unsaturated polymerase gene predict a C-terminal substrate binding domain, 7969 fatty acids, 371 Inhibitors of the cytochrome PAS0 enzymes block the Aorta secretagogue-induced release of corticotropin in mouse pituitary tumor Neuroleptic drugs attenuate calcium influx and tension development in cells, 1012 rabbit thoracic aorta: Effects of pimozide, penfluridol, chlorpromazine, Abnormal polyunsaturated fatty acid patterns of serum lipids in and haloperidol, 1237 alcoholism and cirrhosis: Arachidonic acid deficiency in cirrhosis, 1815 Focal smooth muscle proliferation in the aortic intima produced by an Predominant generation of 15-lipoxygenase metabolites of arachidonic initiation-promotion sequence, 3450 acid by epithelial cells from human trachea, 4633 Aotus Hyperglycemia-induced teratogenesis is mediated by a functional Monkey-derived monoclonal antibodies against Plasmodium deficiency of arachidonic acid, 8227 falciparum, 6272 Thyrotropin upregulates a1-adrenergic receptors in rat FRTL-5 thyroid cells, 8677 Apamin receptor The all-or-none role of innervation in expression of apamin receptor and Archaebacteria of apamin-sensitive Ca2+-activated K+ channel in mammalian skeletal Pattern analysis of 5S rRNA, 2437 muscle, 2188 Structure and sequence divergence of two archaebacterial genes, 4207 8848 Subject Index Proc. Natl. Acad. Sci. USA 82 (1985)

Archaeology Aspartate transcarbamoylase Bird remains from an archaeological site on Henderson Island, South Regeneration of active enzyme by formation of hybrids from inactive Pacific: Man-caused extinctions on an "uninhabited" island, 6191 derivatives: Implications for active sites shared between polypeptide chains of aspartqte transcarbamoylase, 361 Ar.-Gly-Asp Structure at a 2.9-A resolution of aspartate carbamoyltransferase e effect of Arg-Gly-Asp-containing peptides on fibrinogen and von complexed with the bisubstrate analogue N-(phosphonacetyl)- Willebrand factor binding to platelets, 8057 L-aspartate, 1643 Regulation of aspartate transcarbamoylase synthesis in Escherichia coli: Arghtase Analysis of deletion mutations in the promoter region of the pyrBI Point mutation generates constitutive expression of an inducible operon, 4643 eukaryotic gene, 643 Aspartic acid Arghtine RAD6 gene of Saccharomyces cerevisiae encodes a protein containing a Covalent modification of the iron protein of nitrogenase from tract of 13 consecutive aspartates, 168 Rhodospirillum rubrum by adenosine diphosphoribosylation of a specific arginine residue, 3173 Primary structure of rat thymus prothymosin a, 343 Arginine in the leader peptide is required for both import and proteolytic Aspartic proteane cleavage of a mitochondrial precursor, 4930 Cloning and sequence analysis of cDNA for human cathepsin D, 4910 Reversibility of arginine-specific mono(ADP-ribosyl)ation: Identification in erythrocytes of an ADP-ribose-L-arginine cleavage enzyme, 5603 Aspergillus niddaWs Argininosuccinate synthetase: Essential role of cysteine and arginine 3C NMR studies of carbon metabolism in the hyphal fungus Aspergillus residues in relation to structure and mechanism of ATP nidulans, 14 activation, 6745 A cosmid for selecting genes by complementation in Aspergillus nidulans: Selection of the developmentally regulated yA locus, 834 Argiulnosuccinate synthetase Argininosuccinate synthetase: Essential role of cysteine and arginine residues in relation to structure and mechanism of ATP Modes of action of aspirin-like drugs, 7227 activation, 6745 Assimilation arl gene Contrast and assimilation in the perception of brightness, 5983 DNA from recombinogenic bacteriophages generated by arl mutants of Escherichia coli is cleaved by single-strand-specific endonuclease S1 Associative conditioning (Retraction), 953 Associative conditioning analog selectively increases cAMP levels of tail sensory neurons in 2548 AromatizatMon Aplysia, 19-Hydroxylation of androgens in the rat brain, 2728 Astroglia 5-Azacytidine and sodium butyrate induce expression of aromatase in Peptides from regenerating central nervous system promote specific fibroblasts from chickens carrying the henny feathering trait but not populations of macroglia, 4287 from wild-type chickens, 3005 Astroglial cell Arsenazo m Establishment of a line of human fetal glial cells that supports JC virus Regional distribution of calcium influx into bursting neurons detected multiplication, 1257 with arsenazo III, 5565 Asymptote Arsenite The eigenfunction problem in higher dimensions: Asymptotic Induction of heat shock and stress proteins in promastigotes of three Leishmania species, 4414 theory, 8275 Artery Ateks geoffroyi Pulse-wave propagation in an artery with leakage into small side Nucleotide sequence, evolution, and expression of the fetal globin gene branches, 5237 of the spider monkey Ateles geoffroyi, 6985 Atherosclerosis Arthritis Unmodified low density lipoprotein causes cholesteryl ester accumulation Arthritis induced by a T-lymphocyte clone that responds to in J774 macrophages, 416 Mycobacterium tuberculosis and to cartilage proteoglycans, 5117 Focal smooth muscle proliferation in the aortic intima produced by an Arthritis, rheumatoid initiation-promotion sequence, 3450 A third viral nuclear protein in lymphoblasts immortalized by Endothelial cell-derived chemotactic activity for mouse peritoneal 5944 macrophages and the effects of modified forms of low density Epstein-Barr virus, lipoprotein, 5949 Arthropod Human apolipoprotein B cDNA clone isolation and demonstration that Centipedal hemocyanin: Its structure and its implications for arthropod liver apolipoprotein B mRNA is 22 kilobases in length, 6825 phylogeny, 3721 Molecular cloning and expression of partial cDNAs and deduced amino acid sequence of a carboxyl-terminal fragment of human apolipoprotein Arylaminopyridazine B-100, 7265 An arylaminopyridazine derivative of y-aminobutyric acid (GABA) is a selective and competitive antagonist at the GABAA receptor site, 1832 Atom mobility Influence of solvent accessibility and intermolecular contacts on atomic Asbestos mobilities in hemerythrins, 1104 Asbestos-associated chromosomal changes in human mesothelial cells, 3884 Atom, three-electron Note on four-particle wave functions, 1299 Ascorbic add Ascorbic acid mediates acetylcholine receptor increase induced by brain ATP extract of myogenic cells, 575 Phosphorylation enzymes of the propionic acid bacteria and the roles of Effect of dietary ascorbic acid on the incidence of spontaneous mammary ATP, inorganic pyrophosphate, and polyphosphates, 312 tumors in RIII mice, 5185 Transfer RNA is an essential component of the ubiquitin- and The role of ascorbic acid in senile cataract, 7193 ATP-dependent proteolytic system, 1341 Extensive but reversible depletion of ATP via adenylate cyclase in rat Ascorbyl free radical adipocytes, 1614 Enzyme-controlled scavenging of ascorbyl and 2,6-dimethoxy- Evidence that the Mg-dependent low-affinity binding site for ATP and Pi semiquinone free radicals in Ehrlich ascites tumor cells, 1439 demonstrated on the isolated i subunit of the F0F1 ATP synthase is a catalytic site, 1886 Aslalo colony-stimulating factor Mutations in the phosphoglucose isomerase gene can lead to marked Purification and partial amino acid sequence of asialo murine alterations in cellular ATP levels in cultured fibroblasts exposed to granulocyte-macrophage colony stimulating factor, 292 simple nutrient shifts, 2761 Asialoglycoproteln receptor Structure of the actin-myosin complex in the presence of ATP, 3247 An alternative route of infection for viruses: Entry by means of the Application of the principle of linked functions to ATP-driven ion pumps: asialoglycoprotein receptor of a Sendai virus mutant lacking its Kinetics of activation by ATP, 3658 attachment protein, 978 ATP is essential for protein translocation into Escherichia coli membrane Bone marrow engraftment efficiency is enhanced by competitive vesicles, 4384 inhibition of the heptic asialoglycoprotein receptor, 2508 ATP-dependent bioluminescence in the firefly squid, Watasenia Sequence of a second human asialoglycoprotein receptor: Conservation scintillans, 4629 of two receptor genes during evolution, 6465 Thermodynamic and kinetic cooperativity in ligand binding to multiple sites on a protein: Ca2+ activation of an ATP-driven Ca pump, 4688 Aspartate aminotransferase precursor Argininosuccinate synthetase: Essential role of cysteine and arginine Cloning and sequence analysis of a cDNA encoding porcine residues in relation to structure and mechanism of ATP mitochondrial aspartate aminotransferase precursor, 6065 activation, 6745 A model for actin polymerization and the kinetic effects of ATP Aspartate receptor hydrolysis, 7207 Solubilization of a vectorial transmembrane receptor in functional form: Transition-state stabilization in the mechanism of tyrosyl-tRNA Aspartate receptor of chemotaxis, 4891 synthetase revealed by protein engineering, 7840 Subject Index Proc. Natl. Acad. Sci. USA 82 (1985) 8849

ATP analog The 200- and 150-kDa neurofilament proteins react with IgG Identification of an active site peptide of skeletal myosin after autoantibodies from patients with kuru, Creutzfeldt-Jakob disease, and photoaffinity labeling with N-(4-azido-2-nitrophenyl)-2-aminoethyl other neurologic diseases, 3485 diphosphate, 1575 Synthesis of small nuclear ribonucleoprotein particles by the malarial parasite Plasmodiumfalciparum, 3635 ATP binding site The 200- and 150-kDa neurofilament proteins react with IgG Protein kinase activity associated with the purified rat hepatic autoantibodies from chimpanzees with kuru or Creutzfeldt-Jakob glucocorticoid receptor, 4003 disease; A 62-kDa neurofilament-associated protein reacts with sera from sheep with natural scrapie, 3894 ATP hydrolysis Localization of human factor FVIII inhibitor epitopes to two polypeptide ADP dissociation from actomyosin subfragment 1 is sufficiently slow to 7728 limit the unloaded shortening velocity in vertebrate muscle, 658 fragments, Autocrine ATP synthase Autocrine growth stimulation of a human T-cell lymphoma line by Genomic structure of the cottontail rabbit (Shope) papillomavirus, 1580 interleukin 2, 6932 ATP synthesis Autocytotoicity Mechanism of inhibition of mitochondrial adenosine triphosphatase by Generation and regulation of autocytotoxicity in mixed lymphocyte dicyclohexylcarbodiimide and oligomycin: Relationship to ATP cultures: Evidence for active suppression of autocytotoxic cells, 4508 synthesis, 1589 Investigation of nucleotide binding sites on chloroplast coupling factor 1 Autodigestion with 3'-O-(4-benzoyl)benzoyl adenosine 5'-triphosphate, 1950 Self-degradation of heat shock proteins, 4969 Electron transfer-driven ATP synthesis in Methanococcus voltae is not dependent on a proton electrochemical gradient, 6793 Autoimmune disease Rationale for bone marrow transplantation in the treatment of ATPase autoimmune diseases, 2483 Modulation of stoichiometry of the sarcoplasmic reticulum calcium pump Autoimmunity may enhance thermodynamic efficiency, 98 the mutation a Mechanism of inhibition of mitochondrial adenosine triphosphatase by Immunologic abnormalities of mice bearing gld suggest common pathway for murine nonmalignant lymphoproliferative dicyclohexylcarbodiimide and oligomycin: Relationship to ATP disorders with autoimmunity, 1219 synthesis, 1589 Isolation and analysis of cDNA clones expressing human lupus La Evidence thatthe Mg-dependent low-affinity binding site for ATP and Pi antigen, 2115 demonstrated on the isolated 0 subunit of the FoF1 ATP synthase is a Generation and of autocytotoxicity in mixed lymphocyte catalytic site, 1886 regulation 4508 Application of the principle of linked functions to ATP-driven ion pumps: cultures: Evidence for active suppression of autocytotoxic cells, Arthritis induced by a T-lymphocyte clone that responds to Kinetics of activation by ATP, 3658 Mycobacterium tuberculosis and to cartilage proteoglycans, 5117 ATPase, Ca2+- A role for suppressor T cells in induction of self-tolerance, 5150 Milrinone and thyroid hormone stimulate myocardial membrane Induction of experimental allergic encephalomyelitis in Lewis rats with Ca2+-ATPase activity and share structural homologies, 7974 purified synthetic peptides: Delineation of antigenic determinants for encephalitogenicity, in vitro activation of cellular transfer, and ATPae, Ca2+,M42+- proliferation of lymphocytes, 5515 Direct demonstration of structural changes in soluble, monomeric Prazosin, an a1-adrenergic receptor antagonist, suppresses experimental Ca2+-ATPase associated with Ca2+ release during the transport autoimmune encephalomyelitis in the Lewis rat, 5915 cycle, 4573 In vivo prevention of thyroid and pancreatic autoimmunity in the BB rat by antibody to class II major histocompatibility complex gene ATPase, Ft products, 6627 Nucleotide sequence of F0-ATPase proteolipid (subunit 9) gene of maize cDNA cloning of a human autoimmune nuclear ribonucleoprotein mitochondria, 1015 antigen, 7914 Studies on the mechanism of oxidative phosphorylation: Effects of Autoimmune anti-androgen-receptor antibodies in human serum, 8345 specific Fo modifiers on ligand-induced conformation changes of Region of peptide 125-147 of acetylcholine receptor a subunit is exposed F1, 7550 at neuromuscular junction and induces experimental autoimmune Subunit stoichiometry and juxtaposition of the photosynthetic coupling myasthenia gravis, T-cell immunity, and modulating factor 1: Immunoelectron microscopy using monoclonal autoantibodies, 8805 antibodies, 7874 Autophosphorylation ATPase, Na+,K+- Calmodulin binding to the cytoskeletal neuronal calmodulin-dependent Correlation of ouabain-sensitive ion movements with cell-cycle protein kinase is regulated by autophosphorylation, 287 activation, 1599 Expression of autophosphorylating protein kinase 500 in normal and Glucostatic regulation of (+)-[3Hlamphetamine binding in the neoplastic rat cells, 5035 hypothalamus: Correlation with Na+,K+-ATPase activity, 6320 Expression of a functional human insulin receptor from a cloned cDNA Molecular cloning of rat brain Na,K-ATPase a-subunit cDNA, 6357 in Chinese hamster ovary cells, 8014 Incorporation of membrane potential into theoretical analysis of electrogenic ion pumps, 6869 Autoprotease Sequence analysis of three Sindbis virus mutants temperature-sensitive in ATPase, RNA-dependent the capsid protein autoprotease, 4648 Escherichia coli transcription termination factor p has a two-domain structure in its activated form, 1911 Autoradiographic subtraction Visualization of IA opiate receptors in rat brain by using a computerized Atrial natriuretic factor autoradiographic subtraction technique, 6667 Atrial natriuretic factor inhibits dehydration- and angiotensin II-induced water intake in the conscious unrestrained rat, 8720 Ausin Active auxin uptake by zucchini membrane vesicles: Quantitation using alt gene ESR volume and ApH determinations, 6541 Interaction of the X site-specific recombination protein Xis with attachment site DNA, 1040 Avian carcinoma virus Mutagenesis of avian carcinoma virus MH2: Only one of two potential Attack complex transforming genes (8gag-myc) transforms fibroblasts, 6389 Multimenc complement component C9 is necessary for killing of Escherichia coli JS by terminal attack complex CSb-9, 4808 Avian carcinoma virus OK10 Nucleotide sequence of two overlapping myc-related genes in avian Attenuation carcinoma virus OK10 and their relation to the myc genes of other Regulation of aspartate transcarbamoylase synthesis in Escherichia coli: viruses and the cell, 2718 Analysis of deletion mutations in the promoter region of the pyrBI operon, 4643 Avian erythroblastosis virus Translation activates the paused transcription complex and restores The ets sequence from the transforming gene of avian erythroblastosis transcription of the trp operon leader region, 4663 virus, E26, has unique domains on human chromosomes 11 and 21: Both loci are transcriptionally active, 7294 Auditory response The putative transforming protein of S13 avian erythroblastosis virus is a Auditory representation of autogenous song in the song system of transmembrane glycoprotein with an associated protein kinase white-crowned sparrows, 5997 activity, 8237 Auditory system Avian leukosis virus Perpetual production of hair cells and maturational changes in hair cell Formation of a transformed follicle is necessary but not sufficient for ultrastructure accompany postembryonic growth in an amphibian development of an avian leukosis virus-induced lymphoma, 213 3911 c-erbB activation in avian leukosis virus-induced erythroblastosis: ear, Clustered integration sites and the arrangement of provirus in the Autism c-erbB alleles, 2287 Demonstration of inter- and intraspecies differences in serotinin binding Presence of retrovirus reverse transcriptase-related gene sequences in sites by antibodies from an autistic child, 612 avian cells lacking endogenous avian leukosis viruses, 5097 Autoandbody Avian myelocytomatosis virus Demonstration of inter- and intraspecies differences in serotinin binding Avian myelocytomatosis virus immortalizes differentiated quail sites by antibodies from an autistic child, 612 chondrocytes, 2756 8850 Subject Index Proc. Natl. Acad. Sci. USA 82 (1985)

Avidin afnit column B-cell growth and differentiation factor A chemically cleavable biotinylated nucleotide: Usefulness in the A high-efficiency cloning system for single hapten-specific B lymphocytes recovery of protein-DNA complexes from avidin affinity that is suitable for assay of putative growth and differentiation columns, 2593 factors, 3395 Interleukin 1 can act as a B-cell Axial next-nearest-neighbor Isng model growth and differentiation factor, 8153 Model of cortical organization embodying a basis for a theory of B-cell growth factor information processing and memory recall, 2364 B-cell rowth factor (B-cell growth factor I or B-cell-stimulating factor, provisional 1) is a differentiation factor for resting B cells and may not Axon induce cell growth, 2465 Giant axonal neuropathy: Acceleration of neurofilament transport in optic The specific induction of myc protooncogene expression in normal axons, 920 human B cells is not a sufficient event for acquisition of competence to Evidence for widespread effects of noradrenaline on axon terminals in 6255 the rat frontal cortex, 945 proliferate, NH2-terminal specificity and axonal localization of adrenocorticotropin B-cell lymphoma binding sites in rat median eminence, 1271 Cross-reactive idiotypes and common antigen binding specificities Ca2' entry in squid axons during voltage-clamp pulses is mainly expressed by a senes of murine B-cell lymphomas: Etiological Na+/Ca2+ exchange, 1847 implications, 3799 Dispersion of growing axons within the optic nerve of the embryonic monkey, 3906 B-celltimulating factor Identification of a unique B-cell-stimulating factor produced by a cloned Axon cross-sectional area dendritic cell, 183 Experimental diabetic neuropathy: Impairment of slow transport with changes in axon cross-sectional area, 7716 B-cell stimulatory factor 1 B-cell stimulatory factor 1 activates resting B cells, 2935 Axon regeneration Transplants of Schwann cell cultures promote axonal regeneration in the B-DNA adult mammalian brain, 6330 Sequence-specific recognition of B-DNA by oligo(N-methylpyrrole- carboxamide)s, 2565 Axon terminal A molecular dynamics simulation of double-helical B-DNA including Differential effects of electrical stimulation of sciatic nerve on metabolic counterions and water, 6537 activity in spinal cord and dorsal root ganglion in the rat, 6010 B lymphoblast Axonal growth Malignant transformation of Bloom syndrome B-lymphoblastoid cell lines Laminin is associated with the "neurite outgrowth-promoting factors" by carcinogens, 5102 found in conditioned media, 2183 B lymphocyte Axonal transport See also B cell Axonal transport of a heat shock protein in the rabbit visual system, 1281 Immunoglobulin JH, Cal and Cy gene rearrangements in human B lymphocytes clonally transformed by Epstein-Barr virus, 556 5-Azacytkdine gpl40, the C3d receptor of human B lymphocytes, is also the Treatment of mice with 5-azacytidine efficiently activates silent retroviral Epstein-Barr virus receptor, 1490 genomes in different tissues, 1451 A high-efficiency cloning system for single hapten-specific B lymphocytes 5-Azacytidine and sodium butyrate induce expression of aromatase in that is suitable for assay of putative growth and differentiation fibroblasts from chickens carrying the henny feathering trait but not factors, 3395 from wild-type chickens, 3005 Mapping of the C3d receptor (CR2)-binding site and a neoantigenic site in 3'-Azldo-3'-deoxythymidine the C3d domain of the third component of complement, 4235 (BW An antiviral that inhibits Inducible transcription of the unrearranged K constant region locus is a 3'-Azido-3'-deoxythymidine A509U): agent common feature of pre-B cells and does not require DNA or protein the infectivity and cytopathic effect of human T-lymphotropic virus synthesis, 5305 type III/lymphadenopathy-associated virus in vitro, 7096 IgM RNA switch from membrane to secretory form is prevented by N44-Azldo-2-nltrophenyl)2-minetyl diphosphate adding antireceptor antibody to bacterial lipopolysaccharide-stimulated Identification ofan active site peptide of skeletal myosin after murine primary B-cell cultures, 7384 photoaffinity labeling with N-(4-azido-2-nitrophenyl)-2-aminoethyl Enrichment of hematopoietic precursor cells and cloning of multipotential diphosphate, 1575 B-lymphocyte precursors, 7414 Three restriction points in the cell cycle of activated murine B Azotobader vineln lymphocytes, 7681 [4Fe-4S]-cluster-depleted Azotobacter vinelandii ferredoxin I: A new 3Fe iron-sulfur protein, 5661 B-lymphocyte differentiation Azotobacter vinelandii nfD- and nifE-encoded polypeptides share Murine plasma cell membrane antigen PC-1: Molecular cloning of cDNA structural homology, 5720 and analysis of expression, 8619 Azurin B-lymphocyte receptor 1H NMR studies of electron exchange rate of Pseudomonas aeruginosa Two separate functions of class II (Ia) molecules: T-cell stimulation and azurin, 2039 B-cell excitation, 516 B cell Bacillus fichenformis See also B lymphocyte Two alkaline phosphatase genes positioned in tandem in Bacillus B cells that simultaneously express surface IgM and IgE in lichen#formis MC14 require different RNA polymerase holoenzymes for Nippostrongylus brasiliensis-infected SJA/9 mice do not provide transcription, 1035 evidence for isotype switching without gene deletion, 511 Identification of B cells in multilineage hematopoietic colonies derived Bacillus subads from cells of patients with lymphocytic lymphoma, 883 Mutations that affect the translation efficiency of Tn9-derived cat gene in B-cell growth factor (B-cell growth factor I or B-cell-stimulating factor, Bacillus subtilis, 173 provisional 1) is a differentiation factor for resting B cells and may not Biomechanics of bacterial walls: Studies of bacterial thread made from induce cell growth, 2465 Bacillus subtilis, 2163 Reactivation by a trans-acting factor of human major histocompatibility Nucleotide sequences of the sporulation gene spoOA and its mutant genes complex Ia gene expression in interspecies hybrids between an of Bacillus subtilis, 2665 Ia-negative human B-cell variant and an Ia-positive mouse B-cell Regulation of expression from the gInA promoter of Bacillus subtilis lymphoma, 5145 requires the ginA gene product, 3375 Anti-immunoglobulin augments the B-cell antigen-presentation function An RNA-DNA copolymer whose synthesis is correlated with the independently of internalization of receptor-antigen complex, 5890 transcriptional requirement for chromosomal initiation in Bacillus The specific induction of myc protooncogene expression in normal subtilis contains ribosomal RNA sequences, 3586 human B cells is not a sufficient event for acquisition of competence to Secretory S complex of Bacillus subtilis forms a large, organized proliferate, 6255 structure when released from ribosomes, 4031 Bacillus subtilis a factor o29 is the product of the sporulation-essential B-cell activation gene spoIIG, 4189 Affinity-purified interleukin 2 induces proliferation of large but not small DNA-damage-inducible (din) loci are transcriptionally activated in B cells, 1518 competent Bacillus subtilis, 6201 Role of the Bp35 cell surface polypeptide in human B-cell Catabolite-resistant sporulation (crsA) mutations in the Bacillus subtilis activation, 1766 RNA polymerase cr3 gene (rpoD) can suppress and be suppressed by B-cell stimulatory factor 1 activates resting B cells, 2935 mutations in spoO genes, 8124 B-cell diferentiation Baclofen Specific 5' and 3' regions of the ischain gene are undermethylated at GABAB-receptor-activated K+ current in voltage-clamped CA3 pyramidal distinct stages of B-cell differentiation, 3809 cells in hippocampal cultures, 1558 B-ceil dflereiatn factor Bacteremia Purification to homogeneity and characterization of human B-cell Protection against Gram-negative bacteremia and endotoxemia with differentiation factor (BCDF or BSFp-2), 5490 human monoclonal IgM antibodies, 1790 B-cel exdtation Bacterial sttachment Two separate functions of class II (Ia) molecules: T-cell stimulation and Adhesion to human cells by Escherichia coli lacking the major subunit of B-cell excitation, 516 a digalactoside-specific pilus-adhesin, 1800 Subject Index Proc. Natl. Acad. Sci. USA 82 (1985) 8851

Bacterlochlorophyll A neutron diffraction study on the location of the polyene chain of retinal Light-harvesting H (B800-B850 complex) structural genes from in bacteriorhodopsin, 3227 Rhodopseudomonas capsulata, 58 Importance of bound divalent cations to the tyrosine deprotonation Excited states and primary photochemical reactions in the photosynthetic during the photocycle of bacteriorhodopsin, 3662 bacterium Heliobacterium chlorum, 6865 Baculovirus expression vector Bacteriophageassembly Modification and secretion of human interleukin 2 produced in insect Thioredoxin is required for filamentous phage assembly, 29 cells by a baculovirus expression vector, 8404 Bacteriophage A Balanwituda Repair of definedsingle base-pair mismatches in Escherichia coli, 503 Larval settlement rate: A leading determinant of structure in an Interaction of the X site-specific recombination protein Xis with ecological community of the marine intertidal zone, 3707 attachment site DNA, 1040 NH2-terminal arm of phage X repressor contributes energy and specificity Band 3 protein to repressor binding and determines the effects of operator Glucose transport protein is structurally and immunologically related to mutations, 2339 band 3 and senescent cell antigen, 1731 Propagation of some human DNA sequences in bacteriophage X vectors Barncle requires mutant Escherichia coli hosts, 2880 Larval settlement rate: A leading determinant of structure in an Genetic rearrangement of DNA induces knots with a unique topology: 3707 Implicationsfor the mechanism of synapsis and crossing-over, 3124 ecological community of the marine intertidal zone, AcII-dependent promoter is located within the Q gene of bacteriophage Bae-ex envyme X, 3134 of a somatic-cell mutant defective in phosphatidylserine Initiation of DNAreplication on single-stranded DNA templates Isolationbiosynthesis, 1926 catalyzed by purified replication proteins of bacteriophage X and Escherichia coli, 3988 Base mispaira Evidence that ribosomal proteinS10 itself is a cellular component A fidefity assay using "dideoxy" DNA sequencing: A measurement of necessary for transcription antitermination by phage X N protein, 4070 sequence dependence and frequency of forming 5-bromouracil-guanine Specialized nucleoprotei structures at the origin of replication of base mispairs, 1301 bacteriophage X: Complexes with X 0 protein and with X 0, X P, and Escherichia coli DnaB proteins, 4678 Base modification Secondary structure of the circular form of the Tetrahymena rRNA Bacteriophage k clning intervening sequence: A technique for RNA structure analysisusing Replication-competent Moloney murine leukemia virus carrying a chemical probes and reverse transcriptase, 648 bacterial suppressor tRNA gene: Selective cloning of proviral and flanking host sequences, 1141 Basent membrane Basement membrane heparan sulfate proteoglycans are concentrated in Bacteriophage Agt1l thelaminae rarae and in podocytes of the rat renal glomerulus, 3296 Precise localization of genes on large animal virus genomes: Use of Xgtll Restricted homology between human al type IV and other procollagen and monoclonal antibodies to map the gene for a cytomegalovirus chains, 3649 protein family, 1266 The Clq subunit of the first component of complement binds tolaminin: A mechanism for the and retention of immune complexes in Bacteriophage M13 basement membrane, deposition3824 Rapid and efficient site-specific mutagenesis without phenotypic selection, 488 Bathorhodopsin Mutagenesis of the lac promoter region in M13 mplO phage DNA by The primary process of vision and the structure of bathorhodopsin: A 4'-hydroxymethyl-4,5',8-trimethylpsoralen, 7355 mechanismfor photoisomerization of polyenes, 259 Bacteriophage Mu Batrachotoxin DNA sequences at the ends of the genome of bacteriophage Mu essential Batrachotoxin changes the properties of the muscarinic receptor in rat for transposition, 2087 brain and heart: Possible interaction(s) between muscarinic receptors Application of the mini-Mu-phage for target-sequence-specific insertional and sodium channels, 3524 mutagenesis of the herpes simplex virus genome, 4773 A defined system for the DNA strand-transfer reaction at the initiation of Bay K 8644 bacteriophage Mu transposition: Protein and DNA substrate Long-opening mode of gating of neuronal calcium channels and its requirements, 7570 promotion by the dihydropyridine calcium agonist Bay K 8644, 2178 Primary structure of phage Mu transposase: Homology to Mu Bayesesmatin repressor, 7676 Linear empirical Bayes estimation of means and variances, 1571 Bacteriophage P1 Bean P1 plasmid replication: Multiple functions of RepA protein at the Developmentally regulated expression of the bean 0-phaseolin gene in origin, 2588 tobacco seed, 3320 Bacteriophage #29 Bean golden mosaic virus Replication of phage 429 DNA withpurified terminal protein and DNA Nucleotide sequence of bean golden mosaic virus and a model for gene polymerase: Synthesis of full-length 429 DNA, 6404 regulation in geminiviruses, 3572 Bacteriophage 480 Bee Generation of single base-pair deletions, insertions, and substitutions by Kin discrimination by worker honey bees in genetically mixed a site-specific recombination system, 6990 groups, 3058 Bacteriophage #X174 Flower petal microtexture is a tactile cue for bees, 4750 uvrA and recA mutations inhibit a site-specific transition produced by a Brood care by male bumble bees, 6371 single 06-methylguanine in gene G of bacteriophage OX174, 7173 Behavior Bacteriophage S13 Size and behavior in ants: Constraints on complexity, 8548 UV-induced mutagenesis of phage S13 can occur in the absence of the Behavioral treatment RecA and UmuC proteins of Escherichia coli, 6614 Behavioral method for the treatment of idiopathic scoliosis, 2493 Bacteriophage T4 Jones protn A genetic screen for mutations that increase the thermal stability of Bence phage T4 lysozyme, 747 HumanA lght-chain constant region gene CxMcr: The primary structure Cloning, nucleotide sequence, and overexpression of the bacteriophage of XVI Bence Jones protein Mor, 3415 T4 regA gene, 1901 Beazamide A defective phage system reveals bacteriophage T4 replication origins Preferential binding of benzo[a]pyrene diol epoxide to the linker DNA of that coincide with recombination hot spots, 3345 human foreskin fibroblasts in S phase in the presence of Expression of a cloned denV gene of bacteriophage T4 in Escherichia benzamide, 2769 coli, 4763 Substituted benzamides as for visualization of dopamine receptor Mass distribution of a probable tail-length-determining protein in in the human brainligands emission tomography, 3863 bacteriophage T4, 5550 binding by positron Genetic complementation of UV-induced DNA repair in Chinese hamster Benzo[alpyrene ovary cells by the denV gene of phage T4, 7656 Induction of transformation and continuous cell lines from normal human Ion etching of bacteriophage T4: Support for a spiral-fold model of mammary epithelial cells after exposure to benzo[a]pyrene, 2394 packaged DNA, 7960 metabolic activity in embryonic and extraembryonic Cytochrometissue lineagesP4S0of mouse embryos, 3311 Bacteriophage 17 to DNA in polytene chromosomes, 7076 Thioredoxin is required for filamentous phage assembly, 29 Site-specific carcinogen binding A bacteriophage Ti RNA polymerase/promoter system for controlled Benzolalpyrene diol epoxide exclusive expression of specific genes, 1074 Preferential binding of benzo[a]pyrene diol epoxide to the linker DNA of Bacteriophage T7 DNA polymerase: Cloning and high-level human foreskin fibroblasts in S phase in the presence of expression, 6783 benzamide, 2769 Detection of diol epoxide-DNA adducts in peripheral Bateriorhodopsin blood lymphocytesbenzola]pyreneand antibodies to the adducts in serum from coke Cation binding by bacteriorhodopsin, 396 oven workers, 6672 8852 Subject Index Proc. Nati. Acad. Sci. USA 82 (1985)

Benzodiaepine Bipolaroxin Inhibition of Ca2+ conductance in identified leech neurons by Bipolaroxin, a selective phytotoxin produced by Bipolaris benzodiazepines, 3935 cynodontis, 8291 Peripheral-type benzodiazepines influence ornithine decarboxylase levels and neurite outgrowth in PC12 cells, 5223 Bird Demonstration of benzodiazepine-like molecules in the mammalian brain Bird remains from an archaeological site on Henderson Island, South with a monoclonal antibody to benzodiazepines, 5560 Pacific: Man-caused extinctions on an "uninhabited" island, 6191 Benzodiazepine receptor N,N'-Bis(2dchloroethyl)-N-nitrosurea Monoclonal antibodies reveal structural homogeneity of -t-aminobutyric Alkylating agent resistance: In vitro studies with human cell lines, 2158 acid/benzodiazepine receptors in different brain areas, 4837 Blastocyst Benzodiazepine/y-aminobutyric acid receptor deficit in the midbrain of Midgestational abnormalities associated with in vitro preimplantation the seizure-susceptible gerbil, 6701 N-methyl-N-nitrosourea exposure with subsequent transfer to surrogate Benzomorphan opiate mothers, 8757 Demonstration and affinity labeling of a stereoselective binding site for a Blastula benzomorphan opiate on acetylcholine receptor-rich membranes from Characterization of toposomes from sea urchin blastula cells: A cell Torpedo electroplaque, 940 organelle mediating cell adhesion and expressing positional 3'-O-(4-Benzoyl)benzoyladenoslne 5'-triphosphate information, 8062 Investigation of nucleotide binding sites on chloroplast coupling factor 1 Biood coaulatin with 3'-O-(4-benzoyl)benzoyl adenosine 5'-triphosphate, 1950 Inteal duplication and sequence homology in factors V and VIII, 1688 An endothelial cell-dependent pathway of coagulation, 2523 2-Benzyl-3-formylpropanoic acid Evidence for a prevalent dimorphism in the activation peptide of human Binding of a possible transition state analogue to the active site of coagulation factor IX, 2847 carboxypeptidase A, 6840 Characterization ofan almost full-length cDNA coding for human blood Beta vulgaris coagulation factor X, 3591 Nitrate storage and retrieval in Beta vulgaris: Effects of nitrate and Polymorphism of normal factor IX detected by mouse monoclonal chloride on proton gradients in tonoplast vesicles, 3683 antibodies, 3839 The nucleotide sequence of the gene for human protein C, 4673 Betaine Purified human factor VIII procoagulant protein: Comparative hemostatic Betaine synthesis in chenopods: Localization in chloroplasts, 3678 response after infusions into hemophilic and von Willebrand disease dogs, 8752 Bicuculline An arylaminopyridazine derivative of y-aminobutyric acid (GABA) is a Blood findin selective and competitive antagonist at the GABAA receptor site, 1832 Enhanced mosquito blood-finding success on parasitemic hosts: Evidence for vector-parasite mutualism, 7725 Bile The liver excretes large amounts of heme in bile when heme oxygenase is Blood flow inhibited competitively by Sn-protoporphyrin, 8% Functional mapping of the human cerebellum with positron emission tomography, 7462 Bile salt Nasal absorption of insulin: Enhancement by hydrophobic bile salts, 7419 Biood group A5 Repetitive A epitope (type 3 chain A) defined by blood group A1-specific Bilirubin monoclonal antibody TH-1: Chemical basis of qualitative A1 and A2 The liver excretes large amounts of heme in bile when heme oxygenase is distinction, 1199 inhibited competitively by Sn-protoporphyrin, 8% Repetitive A epitope (type 3 chain A) defined by blood group Al-specific Dissociation from albumin: A potentially rate-limiting step in the monoclonal antiby TH-1: Chemical basis of qualitative A1 and A2 clearance of substances by the liver, 1563 distinction (Correction), 3948 Blood group A cross-reacting epitope defined by monoclonal antibodies Binocular interaction NCC-LU-35 and -81 expressed in cancer of blood group 0 or B Functional organization of the cat's visual cortex after prenatal individuals: Its identification as Tn antigen, 7039 interruption of binocular interactions, 3901 Functional organization of the cat's visual cortex after prenatal Biood screening interruption of binocular interactions (Correction), 6019 Bacterial expression of the acquired immunodeficiency syndrome retrovirus p24 gag protein and its use as a diagnostic reagent, 7748 Blochip The molecular electronic device and the biochip computer: Present Blood stage antigen status, 1874 A blood stage antigen of Plasmodium falciparum shares determinants with the sporozoite coat protein, 5121 Bioenergetics Response of patients in classes III and IV of cardiomyopathy to therapy Biood vessel in a blind and crossover trial with coenzyme Qio, 4240 Preferential orientation of centrioles toward the heart in endothelial cells of major blood vessels is reestablished after reversal of a Biofeedback segment, 3272 Behavioral method for the treatment of idiopathic scoliosis, 2493 Bloom syndrome Bioluminescence Malignant transformation of Bloom syndrome B-lymphoblastoid cell lines Cloning and sequence analysis of cDNA for the luminescent protein by carcinogens, 5102 aequorin, 3154 ATP-dependent bioluminescence in the firefly squid, Watasenia bml2 gene scintillans, 4629 The murine bml2 gene conversion provides evidence that T cells Acyl-acyl carrier protein as a source of fatty acids for bacterial recognize predominantly Ia conformation, 7058 bioluminescence, 6085 Cloning of firefly luciferase cDNA and the expression of active luciferase Bombesin in Escherichia coli, 7870 High-affinity receptors for peptides of the bombesin family in Swiss 3T3 cells, 7616 Biomineralization Interactions between acidic proteins and crystals: Stereochemical Bombu gnseocolis requirements in biomineralization, 4110 Brood care by male bumble bees, 6371 Biotin Boxubyx mon Cloning and expression of the 1.3S biotin-containing subunit of Silknoth chorion gene families contain patchwork patterns of sequence transcarboxylase, 5617 homology, 2814 Biotinylated nuceotide Bond, resoating covalent A chemically cleavable biotinylated nucleotide: Usefulness in the Extension of the statistical theory of resonating valence bonds to recovery of protein-DNA complexes from avidin affinity hyperelectronic metals, 8284 columns, 2593 Bond11 Biotinylation Topology of bonding in ir-electron systems, 1 A rapid and sensitive method for detection and quantification of Correlation between catalytic activity and bonding and coordination calcineurin and calmodulin-binding proteins using biotinylated number of atoms and molecules on transition metal surfaces: Theory calmodulin, 7585 and experimental evidence, 2207 Bipolar cell Bon Synaptic transmission of rods to bipolar cells in the tiger salamander Purification and characterization of two cartilage-inducing factors from retina, 3944 bovine demineralized bone, 2267 The propeptide of rat bone y-carboxyglutamic acid protein shares Bipolaris cynodontis homology with other vitamin K-dependent protein precursors, 6109 Bipolaroxin, a selective phytotoxin produced by Bipolaris Immunological detection of hemoglobin in bones of ancient Roman times cynodontis, 8291 and of Iron and Eneolithic Ages, 7170 Subject Index Proc. Natl. Acad. Sci. USA 82 (1985) 8853

Bone-derived growth factor Substituted benzamides as ligands for visualization of dopamine receptor Transforming and nontransforming growth factors are present in medium binding in the human brain by positron emission tomography, 3863 conditioned by fetal rat calvariae, 7335 Identification of substance P precursor forms in human brain tissue, 3921 Bone marrow Brain isozyme Interferon is a mediator of hematopoietic suppression in aplastic anemia X-ADH is the sole alcohol dehydrogenase isozyme of mammalian brains: in vitro and possibly in vivo, 188 Implications and inferences, 8369 Generation of functional clonal cell lines from human bone marrow stroma, 3477 Brain, mmal Differentiation of normal marrow and HL60 cells induced by Demonstration of benzodiazepine-like molecules in the mammalian brain antithymocyte globulin, 4823 with a monoclonal antibody to benzodiazepines, 5560 1,25-Dihydroxyvitamin D% causes formation of multinucleated cells with Brain microvessel several osteoclast characteristics in cultures of primate marrow, 8213 Angiotensin H receptor binding sites in brain microvessels, 6340 Bone marrow chimera Brain, mouse H-2-incompatible bone marrow chimeras produce donor-H-2-restricted Failure to demonstrate pluripotential hemopoietic stem cells in mouse Ly-2 suppressor T-cell factor(s), 7063 brains, 4268 Bone marrow transplantation Rationale for bone marrow transplantation in the treatment of Brain, rat autoimmune diseases, 2483 Different effects of N-ethylmalemide on Ml and M2 muscarine receptors Bone marrow engraftment efficiency is enhanced by competitive in rat brain, 580 Purification and characterization of the u opiate receptor from rat brain inhibition of the hepatic asialoglycoprotein receptor, 2508 using affinity chromatography, 594 Prevention of type I diabetes in nonobese diabetic mice by allogeneic Involvement of the nerve growth factor-inducible large external bone marrow transplantation, 7743 glycoprotein (NILE) in neurite fasciculation in primary cultures of rat Bone resorption brain, 1276 a and human transforming growth factors stimulate prostaglandin 'H-Observe/13C-decouple spectroscopic measurements of lactate and production and bone resorption in cultured mouse calvaria, 4535 glutamate in the rat brain in vivo, 1633 Characterization of [H][2-D-penicillamine, 5-D-penicillamine]enkephalin Botullnum neurotoxin binding to 8 opiate receptors in the rat brain and neuroblastoma-glioma Channels formed by botulinum, tetanus, and diphtheria toxins in planar hybrid cell line (NG 108-15), 2543 lipid bilayers: Relevance to translocation of proteins across 19-Hydroxylation of androgens in the rat brain, 2728 membranes, 1692 1H homonuclear editing of rat brain using semiselective pulses, 3115 Transferrin receptors in rat brain: Neuropeptide-like pattern and Bovine leukemia virus Complete nucleotide sequence of the genome of bovine leukemia virus: relationship to iron distribution, 4553 Its evolutionary relationship to other retroviruses, 677 Molecular cloning and the nucleotide sequence of cDNA for Identification and some biochemical properties of the major XBL gene neuron-specific enolase messenger RNA of rat brain, 7453 product of bovine leukemia virus, 7879 Brain-specific polypeptide 1B236 Bovine papillomavirus Brain-specific polypeptide 1B236 exists in multiple molecular forms, 2009 Bovine papillomavirus contains multiple transforming genes, 1030 Brain transplant Bowman-Birk protease inhibitor Transplants of Schwann cell cultures promote axonal regeneration in the Nanomolar concentrations of Bowman-Birk soybean protease inhibitor adult mammalian brain, 6330 suppress x-ray-induced transformation in vitro, 5395 Brain volume Bp35 cell surface protein Size and behavior in ants: Constraints on complexity, 8548 Role of the Bp35 cell surface polypeptide in human B-cell Brainstem activation, 1766 Increased angiotensin II binding affinity in the nucleus tractus solitarius Brrhizobiuwm of spontaneously hypertensive rats, 7721 Isolation and characterization of nodulation genes from Bradyrhizobium Breast cancer sp. (Vigna) strain IRc 78, 7379 Immunocytochemical staining of estrogen receptor in paraffin sections of Brain human breast cancer by use of monoclonal antibody: Comparison with Functional reconstitution of the purified brain sodium channel in planar that in frozen sections, 4803 lipid bilayers, 240 Estradiol 16a-hydroxylation in the mouse correlates with mammary Isolation of morphine from toad skin, 1852 tumor incidence and presence of murine mammary tumor virus: A The molecular electronic device and the biochip computer: Present possible model for the hormonal etiology of breast cancer in status, 1874 humans, 6295 In vivo solvent-suppressed localized hydrogen nuclear magnetic Cloning of the human estrogen receptor cDNA, 7889 resonance spectroscopy: A window to metabolism?, 2148 Antibodies against the carboxyl-terminal 5-kDa peptide of the a subunit Breast carcinoma of transducin crossreact with the 40-kDa but not the 39-kDa guanine Characterization of a protein, released by the T47D cell line, from brain, 4095 immunologically related to the major envelope protein of mouse nucleotide binding protein mammary tumor virus, 1531 Monoclonal antibodies reveal structural homogeneity of y-faminobutyric acid/benzodiazepine receptors in different brain areas, 4837 Brain and muscle nicotinic acetylcholine receptors are different but Brightness homologous proteins, 5208 Contrast and assimilation in the perception of brightness, 5983 Dissociated cell culture of cholinergic neurons from nucleus basalis of Brome mosaic virus RNA Meynert and other basal forebrain nuclei, 6325 Deletions in the 3'-terminal tRNA-like structure of brome mosaic virus Brain, bovine RNA differentially affect aminoacylation and replication in vitro, 5636 Morphine and other opiates from beef brain and adrenal, 5203 5-Bromouracilguanine base mispair Purification and characterization of a neurite extension factor from A fidelity assay using "dideoxy" DNA sequencing: A measurement of bovine brain, 7136 sequence dependence and frequency of forming 5-brpmouracil-guanine Brain, developing base mispairs, 1301 A large intracellular pool of inactive Na channel a subunits in developing Brown adipose tissue rat brain, 4847 Molecular approach to thermogenesis in brown adipose tissue: cDNA Brain development cloning of the mitochondrial uncoupling protein, 445 Differential expression of distinct microtubule-associated proteins during brain development, 6006 Brownian motion Nerve growth factor promotes cholinergic development in brain striatal Probabilistic aspects of finite-fuel stochastic control, 5579 cultures, 7777 Brush border Brain, embryonic Can villin be used to identify malignant and undifferentiated normal Fucose-containing glycolipids are stage- and region-specific antigens in digestive epithelial cells?, 8488 brain of 3045 developing embryonic rodents, ufo marinus Brain graft Isolation of morphine from toad skin, 1852 Cholinergic ventral forebrain grafts into the neocortex improve passive Perpetual production of hair cells and maturational changes in hair cell avoidance memory in a rat model of Alzheimer disease, 5227 ultrastructure accompany postembryonic growth in an amphibian ear, 3911 h devde BrA*Bifeetial expression of the mouse cholecystokinin gene during brain a-Bungarotoxln and gut development, 5593 Antilodies to synthetic peptides as probes for the binding site on the a subunit of the acetylcholine receptor, 3490 Brain, human Determination of the primary amino acid sequence specifying the Insulin-like growth factor H (IGF II) in human brain: Regional a-bungarotoxin binding site on the a subunit of the acetylcholine distribution of IGF II and of higher molecular mass forms, 2153 receptor from Torpedo californica, 8790 8854 Subject Index Proc. Natl. Acad. Sci. USA 82 (1985)

Burkitt lymphoma The c-myc oncogene is translocated to the involved chramome-42 in Chromatin structure around the c-myc gene in Burkitt lymphomas with mouse plasmacytoma, 4212 upstream and downstream translocation points, 1984 Regulation of c-myc mRNA levels in normal human-lympbvytes--by modulators of cell proliferation, 4221 Bursal transplantation Increased rate of degradation of c-myc mRNA in interferoa-rated Daudi A retrovirual myc gene induces preneoplastic transformation of cells, 4896 lymphocytes in a bursal transplantation assay, 222 c-myc mRNA levels in the cell cycle change in mouse erytbroleukemia Burst-promoting activity cells following inducer treatment, 5323 Interleukin 3 promotes erythroid burst formation in "serum-free" cultures Gene localization on sorted chromosomes: Definitive evidence on the without detectable erythropoietin, relative positioning of genes participating in the mouse 3291 plasmacytoma-associated typical translocation, 6975 Buthionine sulfoximine Translocation of c-myc in the hereditary renal cell carcinoma associated Origin and turnover of mitochondrial glutathione, 4668 with a t(3;8)(p14.2;q24.13) chromosomal translocation, 698O Molecular cloning and regulated expression of the human c-myc gene in 2-(sec-Butyl)dihydrothlazole Escherichia coli and Saccharomyces cerevisiae: Comparison of the Synthetic pheromones that promote inter-male aggression in mice, 2059 protein products, 7232 Butyrate Mapping of functional domains in adenovirus ElA proteins, 7480 5-Azacytidine and sodium butyrate induce expression of aromatase in C peptide fibroblasts from chickens carrying the henny feathering trait but not ature of the charged-group effect on the stability of the C-peptide from wild-type chickens, 3005 helix, 2349 Bu rylchnetr c-sis gene Gelycyl-L-glutamine, a precursor, and glycyl-L-glutamic acid, a Synthesis and secretion of proteins resembling platelet-derived growth neurotrophic factor or maintenance of acetylcholinesterase and factor by human glioblastoma and fibrosarcoma cells in culture, 2404 butyrylcholinesterase in the preganglionically denervated superior cervical ganglion of the cat in vivo, 5213 c-src gene c-src is consistently conserved in the chromosomal deletion (20q) bz locus observed in myeloid disorders, 6692 Deletions within a defective Suppressor-mutator element in maize affect The product of the protooncogene c-src is modified during the cellular the frequency and developmental timing of its excision from the bronze response to platelet-derived growth factor, 7845 locus, 4783 cab gene c-abl gene Prenatal expression of a lethal genetic defect in carbohydrate metabolism Cell lines and clinical isolates derived from Ph -positive chronic in mice, 2101 myelogenous leukemia patients express c-abl proteins with a common Inheritance, organization, and mapping of rbcS and cab multigene structural alteration, 1810 families in pea, 5083 Chromosomal localization and characterization of c-abl in the t(6;9) of acute nonlymphocytic leukemia, 8742 CAD protein Oligomeric structure of the multifunctional protein CAD that initiates c-erbB gene pyrimidine biosynthesis in mammalian cells, 6802 c-erbB activation in avian leukosis virus-induced erythroblastosis: Clustered integration sites and the arrangement of provirus in the Caenorhabditis elegans c-erbB alleles, 2287 Sex determination: A hypothesis based on noncoding DNA, 1165 A v-erbB-related protooncogene, c-erbB-2, is distinct from the Transposition of Tcl in the nematode Caenorhabditis elegans, 1756 c-erbB-1/epidermal growth factor-receptor gene and is amplified in a Caenorhabditis elegans DNA that directs segregation in yeast cells, 4167 human salivary gland adenocarcinoma, 6497 Caiman crocodyins c-fns gene Complete nucleotide sequences of three VH genes in Caiman, a Restriction fragment length polymorphism of the human c-fms gene, 2862 phylogenetically ancient reptile: Evolutionary diversification in coding segments and variation in the structure and organization of recombination elements, 844 Identification of genes for the constant region of rabbit T-cell receptor chains, 4498 Calcineurin Sequence and evolution of the human T-cell antigen receptor a-chain Stoichiometric methylation of calcineurin by protein carboxyl genes, 5068 Omethyltransferase and its effects on calmodulin-stimulated phosphatase activity, 5612 Ci, gene A rapid and sensitive method for detection and quantification of Human X light-chain constant region gene CxMor: The primary structure calcineurin and calmodulin-binding proteins using biotinylated of XVI Bence Jones protein Mor, 3415 calmodulin, 7585 C3 gene Calcitonin Human complement component C3: cDNA coding sequence and derived Calcitonin gene-related peptide and its binding sites in the human central primary structure, 708 nervous system and pituitary, 248 c-Ha-ras gene Alternative RNA processing events in human calcitonin/calcitonin Plasmid-induced "hit-and-run" tumorigenesis in Chinese hamster embryo gene-related peptide gene expression, 1994 fibroblast (CHEF) cells, 2839 Linkage map of the short arm of human chromosome 11: Location of the genes for catalase, calcitonin, and insulin-like growth factor II, 5064 c-nos gene Calcium-regulating hormones modulate carbonic anhydrase II in the Isolation and analysis of the 21q+ chromosome in the acute myelogenous human erythrocyte, 8832 leukemia 8;21 translocation: Evidence that c-mos is not translocated, 464 Calcitonin gene-related peptide Presence of an allelic EcoRI restriction fragment of the c-mos locus in Calcitonin gene-related peptide and its binding sites in the human central leukocyte and tumor cell DNAs of breast cancer patients, 7068 nervous system and pituitary, 248 Alternative RNA processing events in human calcitonin/calcitonin c-myb gene gene-related peptide gene expression, 1994 Comparison of chemically induced and spontaneous murine thymic lymphomas in RF and AKR mice: Differential expression of c-myc and Calcium c-myb, 565 Cation binding by bacteriorhodopsin, 396 Developmental regulation of c-myb in normal myeloid progenitor Phorbol ester effects on neurotransmission: Interaction with cells, 6937 neurotransmitters and calcium in smooth muscle, 604 Intracellular free calcium levels are reduced in mitotic Pt K2 epithelial c-myc gene cells, 800 Transcription of three c-myc exons is enhanced in chicken bursal Effects of phorbol ester on catecholamine secretion and protein lymphoma cell lines, 53 phosphorylation in adrenal medullary cell cultures, 930 Comparison of chemically induced and spontaneous murine thymic GABAB-receptor-activated K+ current in voltage-clamped CA3 pyramidal lymphomas in RF and AKR mice: Differential expression of c-myc and cells in hippocampal cultures, 1558 c-myb, 565 The all-or-none role of innervation in expression of apamin receptor and Major deletions in the gene encoding the p53 tumor antigen cause lack of of apamin-sensitive Ca2+-activated K+ channel in mammalian skeletal p53 expression in HL-60 cells, 790 muscle, 2188 "Retroposon" insertion into the cellular oncogene c-myc in canine Two distinct Ca-dependent K currents in bullfrog sympathetic ganglion transmissible venereal tumor, 1054 cells, 3040 Interferon regulates c-myc gene expression in Daudi cells at the Mechanism of activation of the heme-stabilized translational inhibitor of post-transcriptional level, 1151 reticulocyte lysates by calcium ions and phospholipid, 3119 Chromatin structure around the c-myc gene in Burkitt lymphomas with Importance of bound divalent cations to the tyrosine deprotonation upstream and downstream translocation points, 1984 during the photocycle of bacteriorhodopsin, 3662 Differential efficiencies of in vitro translation of mouse c-myc transcripts Phorbol myristate acetate inhibits thrombin-stimulated Ca2W mobilization differing in the 5' untranslated region, 2315 and phosphatidylinositol 4,5-bisphosphate hydrolysis in human The translocated c-myc oncogene of Raji Burkitt lymphoma cells is not _ platelets, 3859 expressed in human lymphoblastoid cells, 2900 Protein kinase activity associated with the purified rat hepatic Activation of the c-myc oncogene by the immunoplobulin heavy-chain glucocorticoid receptor, 4003 gene enhancer after multiple switch region-mediated chromosome Regulation of vitamin D metabolites of messenger ribonucleic acid for rearrangements in a murine plasmacytoma, 3746 preproparathyroid hormone in isolated bovine parathyroid cells, 4270 Subject Index Proc. Natl. Acad. Sci. USA 82 (1985) 8855

Inositol triaphaphate modification of ion transport in rough endoplasmic Calcium sequestration reticuhm;44B3 Fluctuation of the Ca2+-sequestering activity of permeabilized sea urchin Inostol trisplphate-induced calcium release and contraction in embryos during the cell cycle, 2389 vascuinr zMoth muscle, 5231 Regional lt- ibution of calcium influx into bursting neurons detected Calcium s with arsenazo III, 5565 Calmodulin binding to the cytoskeletal neuronal calmodulin-dependent Inositol 1,4,S4risphosphate: A possible chemical link in protein kinase is regulated by autophosphorylation, 287 excitation-contraction coupling in muscle, 6352 Binding of prtin kinase C to neutrophil membranes in the presence of Calcium transport Ca2' and its activation by a Ca2+-requiring proteinase, 6435 Direct demonstration of structural changes in soluble, monomeric Increases in muscle Ca2+ mediate changes in acetylcholinesterase and Ca2+-ATPase associated with Ca2+ release during the transport acetylchohm receptors caused by muscle contraction, 7121 cycle, 4573 Exposureof ctin thiols by the removal of tightly held calcium ions, 7904 The structure of caltrin, the calcium-transport inhibitor of bovine seminal Identification of calmodulin-dependent protein kinase HI and its major plasma, 6490 Mr 100,000 substrate in mammalian tissues, 7939 Calculus Hormone secrtagogues increase cytosolic calcium by increasing cAMP Calculus of twisted vertex 8295 in corticotropin-secreting cells, 8034 operators, A pertussis toxin-sensitive GTP-binding protein in the human neutrophil Caldesmon regulates multiple receptors, calcium mobilization, and lectin-induced Purification and characterization of caldesmon-n: A calmodulin-binding capping, 8643 protein that interacts with actin filaments from bovine adrenal Intracellular calcium regulates basolateral potassium channels in a medulla, 5025 chloride-secreting epithelium, 8823 Activation of tracheal smooth muscle contraction: Synergism between Callphora erythrocephala Ca2+ and activators of protein kinase C, 8835 A stochastic mechanism controls the relative replication of equally competent ribosomal RNA gene sets in individual dipteran polyploid Calcium action potential nuclei, 5045 , and K opioids inhibit transmitter release by different mechanisms, 1860 Calmodulin Calcium binding Calmodulin binding to the cytoskeletal neuronal calmodulin-dependent Calcium binding in pigmented and albino eyes, 6716 protein kinase is regulated by autophosphorylation, 287 Calcium-binding protein Purification of the Rous sarcoma virus src kinase by casein-agarose and The Ca2+-binding protein parvalbumin: Molecular cloning and tyrosine-agarose affinity chromatography, 321 developmental regulation of mRNA abundance, 1414 The Ca24-binding protein parvalbumin: Molecular cloning and Cloning and sequence analysis of cDNA for the luminescent protein developmental regulation of mRNA abundance, 1414 aequorin, 3154 Calmodulin accelerates the rate of polymerization of human platelet actin Purification and crystallization of the calcium binding protein of and alters the structural characteristics of actin filaments, 1683 sarcoplasmic reticulum from skeletal muscle, 4036 Differential regulation of bovine brain calmodulin-dependent cyclic A putative Ca2+-binding protein: Structure of the light subunit of porcine nucleotide phosphodiesterase isozymes by cyclic AMP-dependent calpain elucidated by molecular cloning and protein sequence protein kinase and calmodulin-dependent phosphatase, 2603 analysis, 6075 Identification of the calmodulin-binding domain of skeletal muscle myosin Stabilization of the long central helix of troponin C by intrahelical salt light chain kinase, 3187 bridges between charged amino acid side chains, 7944 A predicted structure of calmodulin suggests an electrostatic basis for its The neostriatal mosaic: Compartmental distribution of calcium-binding function, 4954 and in the basal of the rat and Stoichiometric methylation of calcineurin by protein carboxyl protein parvalbumin ganglia O-methyltransferase and its effects on calmodulin-stimulated monkey, 8780 phosphatase activity, 5612 Calcium channel A rapid and sensitive method for detection and quantification of Neuroleptic drugs attenuate calcium influx and tension development in calcineurin and calmodulin-binding proteins using biotinylated rabbit thoracic aorta: Effects of pimozide, penfluridol, chlorpromazine, calmodulin, 7585 and haloperidol, 1237 Calcium channel antagonists inhibit the acrosome reaction and bind to Calmodulin-binding Protein plasma membranes of sea urchin sperm, 1460 Purification and characterization of caldesmon-n: A calmodulin-binding Ca + entry in squid axons during voltage-clamp pulses is mainly protein that interacts with actin filaments from bovine adrenal Na+/Ca2+ exchange, 1847 medulla, 5025 Long-opening mode of gating of neuronal calcium channels and its Identification of the catalytic subunit of brain adenylate cyclase: A promotion by the dihydropyridine calcium agonist Bay K 8644, 2178 calmodulin binding protein of 135 kDa, 6736 Phosphorylation of the calcium antagonist receptor of the A rapid and sensitive method for detection and quantification of voltage-sensitive calcium channel by cAMP-dependent protein calcineurin and calmodulin-binding proteins using biotinylated kinase, 2528 calmodulin, 7585 Inhibition of Ca2+ conductance in identified leech neurons by Calmodulin gene benzodiazepines, 3935 Calmodulin genes in trypanosomes are tandemly repeated and produce Dual modulation of K channels by thyrotropin-releasing hormone in mRNAs with a common 5' leader 3998 clonal pituitary cells, 4282 multiple sequence, The Ca channel in skeletal muscle is a large pore, 7149 Calorimetry, differential scanning Localization of Ca2+ release channels with ryanodine in junctional Differential scanning calorimetry of nuclei reveals the loss of major terminal cisternae of sarcoplasmic reticulum of fast skeletal structural features in chromatin by brief nuclease treatment, 2642 muscle, 7256 Calpain Calcium current A putative Ca2+-binding protein: Structure of the light subunit of porcine Transmission at voltage-clamped giant synapse of the squid: Evidence for calpain elucidated by molecular cloning and protein sequence cooperativity of presynaptic calcium action, 622 analysis, 6075 Calcium currents in GH3 cultured pituitary cells under whole-cell voltage-clamp: Inhibition by voltage-dependent potassium Calsequestrin currents, 1108 Purification and crystallization of the calcium binding protein of Optical measurement of voltage-dependent Ca2+ influx in frog heart, 1864 sarcoplasmic reticulum from skeletal muscle, 4036 Ionic currents that generate the spontaneous diastolic depolarization in individual cardiac pacemaker cells, 7796 Caltrin The structure of caltrin, the calcium-transport inhibitor of bovine seminal Calcium dicarboxylate plasma, 6490 Interactions between acidic proteins and crystals: Stereochemical requirements in biomineralization, 4110 Calvarium a and i human transforming growth factors stimulate prostaglandin Calcium influx production and bone resorption in cultured mouse calvaria, 4535 Neuroleptic drugs attenuate calcium influx and tension development in Transforming and nontransforming growth factors are present in medium rabbit thoracic aorta: Effects of pimozide, penfluridol, chlorpromazine, conditioned by fetal rat calvariae, 7335 and haloperidol, 1237 cAMP Calcium lonophore A23187 See AMP Mechanism of calcium ionophore A23187-induced priming of bone Cyclic marrow-derived macrophages for tumor cell killing: Relationship to Cancer priming by interferon, 5959 Effect of dietary ascorbic acid on the incidence of spontaneous mammary Activation of Na+/H+ exchange in cultured fibroblasts: Synergism and tumors in RHI mice, 5185 antagonism between phorbol ester, Ca2+ ionophore, and growth Administration of recombinant interferon y to cancer patients enhances factors, 8053 monocyte secretion of hydrogen peroxide, 8686 Calium pump Cancer, breast Modulation of stoichiometry of the sarcoplasmic reticulum calcium pump Presence of an allelic EcoRI restriction fragment of the c-mos locus in may enhance thermodynamic efficiency, 98 leukocyte and tumor cell DNAs of breast cancer patients, 7068 Thermodynamic and kinetic cooperativity in ligand binding to multiple sites on a protein: Ca2W activation of an ATP-driven Ca pump, 4688 Cancer cell Variable stoichiometry in active ion transport: Theoretical analysis of The hemodynamic destruction of intravascular cancer cells in relation to physiological consequences, 5352 myocardial metastasis, 5737 8856 Subject Index Proc. Natl. Acad. Sci. USA 82 (1985)

Cancer diagnosis Carbonic anhydrase Isolation and characterization of an RNA-proteolipid complex associated Cloned cDNA for rabbit erythrocyte carbonic anhydrase I: A novel with the malignant state in humans, 3455 erythrocyte-specific probe to study development in erythroid tissues, 663 Cancer, familial Carbonic anhydrase is aberrantly and constitutively expressed in both Chromosomal radiosensitivity during the G2 cell-cycle period of skin human and murine erythroleukemia cells, 5175 fibroblasts from individuals with familial cancer, 5400 Calcium-regulating hormones modulate carbonic anhydrase II in the Cancer, lung human erythrocyte, 8832 Blood group A cross-reacting epitope defined by monoclonal antibodies Carbo noxyh gbln NCC-LU-35 and -81 expressed in cancer of blood group 0 or B Reexamination of the evidence for paramagnetism in oxy- and individuals: Its identification as Tn antigen, 7039 carbonmonoxyhemoglobins, 102 Cancer predisposition 2(Carboxy-3'-propyl).3-amino-4-methyl-6phenylpyridazininm chloride Osteosarcoma and retinoblastoma: A shared chromosomal mechanism An arylaminiopyridazine derivative of y-aminobutyric acid (GABA) is a revealing recessive predisposition, 6216 selective and competitive antagonist at the GABAA receptor site, 1832 Cancer-protective enzyme Carboxyglutamlk add protein On the mechanisms of induction of cancer-protective enzymes: A The propeptide of rat bone y-caboxyglutamic acid protein shares unifying proposal, 8232 homology with other vitamin K-dependent protein precursors, 6109 Cancer, renal Carboxypeptidase A Specificity analysis of mouse monoclonal antibodies defining cell surface Alternative view of enzyme reactions, 2225 antigens of human renal cancer, 2955 Binding of a possible transition state analogue to the active site of Specificity analysis of mouse monoclonal antibodies defining cell surface carboxypeptidase A, 6840 antigens of human renal cancer (Correction), 5236 Carboxypeptidase B Cancer, stomach Immunochemical characterization of carboxypeptidase B-like Molecular cloning of an activated human oncogene, homologous to v-raf, peptide-hormone-processing enzyme, 4745 from primary stomach cancer, 5641 Carboxypeptidase, tripeptidyl Cancer therapy Novel activity of htiman angiotensin I converting enzyme: Release of the Purification and characterization of a human tumor necrosis factor from NH2- and COOH-terminal tripeptides from the lutemizing the LuKII cell line, 6637 hormone-releasing hormone, 1025 Cadida albicans Carcinoembryonic antigen Parathymosin a: A peptide for rat tissues with structural homology to Isolation of tumor-secreted products from human carcinoma cells prothymosin a, 1050 maintained in a defined protein-free medium, 5771 Candida tropicals Cloning of cDNA coding for peroxisomal acyl-CoA oxidase from the Carcinogen yeast Candida tropicalis pK233, 3973 Site-specific carcinogen binding to DNA in polytene chromosomes, 7076 Cap binding protein Carcinogeneds Poliovirus does mediate of the Quantitative assessment of the role of O6-methylguanine in the initiation protease not cleavage 220,000-Da of carcinogenesis by methylating agents, 421 component of the cap binding protein complex, 2723 N-Nitrosodialkylamines do not function as substrates for liver Capillary monoamine oxidase, 682 Capillary number and percentage closed in human diabetic sural Induction of transformation and continuous cell lines from normal human nerve, 2513 mammary epithelial cells after exposure to benzo[alpyrene, 2394 Endothelial cells from bovine adrenal medula develop capillary-like An initiator of carcinogenesis selectively and stably inhibits stem cell growth patterns in culture, 4702 differentiation: A concept that initiation of carcinogenesis involves The hemodynamic destruction of intravascular cancer cells in relation to multiple phases, 2995 myocardial metastasis, 5737 Sequence context effects in DNA replication blocks induced by aflatoxin The formation of fenestrations and channels by capillary endothelium in B1, 3096 vitro, 6181 Asbestos-associated chromosomal changes in human mesothelial Erdothelial cells from bovine adrenal medulla develop capillary-like cells, 3884 growth patterns in culture (Correction), 7474 Purification, induction, and distribution of placental glutathione transferase: A new marker enzyme for preneoplastic cells in the rat Capiliary endothelial cell chemical hepatocarcinogenesis, 3964 Heparin affinity of anionic and cationic capillary endothelial cell growth Expression of autophosphorylating protein kinase 500 in normal and factors: Analysis of hypothalamus-derived growth factors and neoplastic rat cells, 5035 fibroblast growth factors, 805 Malignant transformation of Bloom syndrome B-lymphoblastoid cell lines by carcinogens, 5102 Capsid protein Selective alkylation of carcinogenic 9-anthryloxirane at the N-3 position sequence analysis of hepatitis A virus cDNA coding for capsid proteins of adenine in DNA, 5250 and RNA polymerase, 2143 Mutagenesis of avian carcinoma virus MH2: Only one of two potential Sequence analysis of three Sindbis virus mutants temperature-sensitive in transforming genes (8gag-myc) transforms fibroblasts, 6389 the capsid protein autoprotease, 4648 On the mechanisms of induction of cancer-protective enzymes: A Direct mapping of adeno-associated virus capsid proteins B and C: A unifying proposal, 8232 possible ACG initiation codon, 7919 A Carcinogenesis, chemical Capsid protein gene Distribution of initial and persistent 2-acetylaminofluorene-induced DNA Sequence determination of the capsid protein gene and flanking regions adducts within DNA loops, 6605 of tobacco etch virus: Evidence for synthesis and processing of a Detection of benzo[alpyrene diol epoxide-DNA adducts in peripheral polyprotein in potyvirus genome expression, 3969 blood lymphocytes and antibodies to the adducts in serum from coke CARI gene oven workers, 6672 Point mutation generates constitutive expression of an inducible Modification of chromium (VI)-induced DNA damage by glutathione and eukaryotic gene, 643 cytochrome P450 in chicken embryo hepatocytes, 6755 Loss of the normal N-ras allele in a mouse thymic lymphoma induced by Carbamoyl-pho hate aynthetase I a chemical carcinogen, 7810 The gene coding for carbamoyl-phosphate synthetase I was formed by fusion of an ancestral glutaminase gene and a synthetase gene, 2244 Carcinoma cell Amplification of DNA sequences in human multidrug-resistant KB Carbohydrate metabolism carcinoma cells, 7661 Prenatal expression of a lethal genetic defect in carbohydrate metabolism in mice, 2101 Coma, hepa Hepatitis B virus integration in hepatocellular carcinoma DNA: Carbon-13 Duplication of cellular flanking sequences at the integration site, 4458 1H-Observe/13C-decouple spectroscopic measurements of lactate and glutamate in the rat brain in vivo, 1633 Carcinoma, hereditary renal cell Translocation of c-myc in the hereditary renal cell carcinoma associated Carbon metabolism with a t(3;8)(p14.2;q24.13) chromosomal translocation, 6980 13C NMR studies of carbon metabolism in the hyphal fungus Aspergillus nidulans, 14 Carcinoma, mammary Invasiveness and ploidy of human mammary carcinomas in short-term Carbon monoxide culture, 1805 Molecular dynamics simulation of photodissociation of carbon monoxide Monoclonal antibody that defines human myoepithelium, 7409 from hemoglobin, 2034 Kinetics of carbon monoxide binding to phenobarbital-induced Cardiac dysfvncton cytochrome P-450 from rat liver microsomes: A simple bimolecular Cardiac dysfunction caused by purified human C3a anaphylatoxin, 886 process, 4900 Evidence that an iron-nickel-carbon complex is formed by reaction of Cardiodilatin CO with the CO dehydrogenase from Clostridium thermo- Biochemical and immunological evidence for a cardiodilatin-like aceticum, 6811 substance in the snail neurocardiac axis, 7762 Subject Index Proc. Natl. Acad. Sci. USA 82 (1985) 8857

Cardlonyp thy Endothelial cells from bovine adrenal medulla develop capillary-like Biochemical rationale and myocardial tissue data on the effective therapy growth patterns in culture (Correction), 7474 of cardiomyopathy with coenzyme Qio, 901 Differentiation of catecholaminergic cells in cultures of embryonic avian Response of patients in classes III and IV of cardiomyopathy to therapy sensory ganglia, 8800 in a blind and crossover trial with coenzyme 4240 Q1o, Catene Carotid body Determination of the stereostructure of the product of Tn3 resolvase by a Oxygen chemoreception by carotid body cells in culture, 1448 general method, 1079 Carrier protein Cathepon B Hybrid molecules containing the B-domain of insulin-like growth factor I Identification of cDNA clones encoding a precursor of rat liver cathepsin are recognized by carrier proteins of the growth factor, 3010 B, 2320 Carr Cathepsin D a-Amanitin resistance is developmentally regulated in carrot, 2799 Cloning and sequence analysis of cDNA for human cathepsin D, 4910 Isolation and characterization of cDNA clones for carrot extensin and a proline-rich 33-kDa protein, 4399 Cathepsin H Aleurain: A barley thiol protease closely related to mammalian cathepsin Cartilage H, 6512 Identification and characterization of the human type II collagen gene (COL2AJ), 2555 Cation binding Type IX collagen from sternal cartilage of chicken embryo contains Cation binding by bacteriorhodopsin, 396 covalently bound glycosaminoglycans, 2608 Arthritis induced by a T-lymphocyte clone that responds to Caudodorsal cell hormone tuberculosis and to cartilage proteoglycans, 5117 Purification and amino acid sequence of the ovulation neurohormone of Mycobacterium Lymnaea stagnalis, 7767 Cartilage-Inducing factor Purification and characterization of two cartilage-inducing factors from CDC28 gene bovine demineralized bone, 2267 Protein kinase activity associated with the product of the yeast cell division cycle gene CDC28, 4055 Casein Purification of the Rous sarcoma virus src kinase by casein-agarose and cDNA tyrosine-agarose affinity chromatography, 321 Expression of phaseolin cDNA genes in yeast under control of natural Interaction of mouse mammary epithelial cells with collagen substrata: plant DNA sequences, 334 Regulation of casein gene expression and secretion, 1419 Isolation of cDNA for a human granulocyte-macrophage colony-stimulating factor by functional expression in mammalian P-Caseln Gene cells, 4360 Prolactin induces release of a factor from membranes capable of stimulating P-casein gene transcription in isolated mammary cell nuclei cDNA clone (Retraction), 3062 Coding nucleotide sequence of rat NADPH-cytochrome P450 oxidoreductase cDNA and identification of flavin-binding domains, 973 Casein kYiase Isolation and sequence of a human cytochrome P450 cDNA clone, 983 A synthetic peptide substrate specific for casein kinase II, 737 Isolation of a cDNA clone encoding pancreatic polypeptide, 1536 Phosphorylation of DNA topoisomerase II by casein kinase II: Isolation and analysis of cDNA clones expressing human lupus La Modulation of eukaryotic topoisomerase II activity in vitro, 3164 antigen, 2115 Identification of cDNA clones encoding a precursor of rat liver cathepsin C ospen ine B, 2320 Castanospermine inhibits a-glucosidase activities and alters glycogen cDNA clones encoding IgE-binding factors from a rat-mouse T-cell distribution in animals, 93 hybridoma, 2460 Cat Isolation of a cDNA clone for the liver cell adhesion molecule Functional organization of the cat's visual cortex after prenatal (L-CAM), 2809 interruption of binocular interactions, 3901 cDNA clone detection Functional organization of the cat's visual cortex after prenatal Detection and characterization of a mouse a-spectrin cDNA clone by its interruption of binocular interactions (Correction), 6019 expression in Escherichia coli, 1367 cat gene cDNA cloning- Mutations that affect the translation efficiency of Tn9-derived cat gene in Complete coding sequence of rat tyrosine hydroxylase mRNA, 617 Bacillus subtilis, 173 Molecular cloning of a cDNA for human a-L-fucosidase, 1262 Catabolte repression Chicken triosephosphate isomerase complements an Escherichia coli Catabolite-resistant sporulation (crsA) mutations in the Bacillus subtilis deficiency, 2014 43 Molecular cloning of a full-length cDNA for human alcohol RNA polymerase gene (rpoD) can suppress and be suppressed by dehydrogenase, 2703 mutations in spoO genes, 8124 Cloning and sequence analysis of cDNA for the luminescent protein Catagtyphis cursor aequorin, 3154 Preimaginal learning as a basis of colony-brood recognition in the ant Molecular cloning of the genome of a cardiotropic Coxsackie B3 virus: Cataglyphis cursor, 8545 Full-length reverse-transcribed recombinant cDNA generates infectious virus in mammalian cells, 4818 Catalase Molecular cloning of a full-length cDNA for human alcohol The NADPH binding site on beef liver catalase, 1604 dehydrogenase (Correction), 5578 Linkage map of the short arm of human chromosome 11: Location of the Cloning and characterization of two cDNAs coding for human von genes for catalase, calcitonin, and insulin-like growth factor II, 5064 Willebrand factor, 6394 Catalase gene cDNA exon vector Molecular analysis of chromosome 11 deletions in aniridia-Wilms tumor Use of a cDNA expression vector for isolation of mouse interleukin 2 syndrome, 8592 cDNA clones: Expression of T-cell growth-factor activity after transfection of monkey cells, 68 Catalysis Identification of the components necessary for adenovirus translational Correlation between catalytic activity and bonding and coordination control and their utilization in cDNA expression vectors, 689 number of atoms and molecules on transition metal surfaces: Theory and experimental evidence, 2207 cDNA library Enzyme-catalyzed processes in organic solvents, 3192 Murine plasma cell membrane antigen PC-1: Molecular cloning of cDNA Hardness, softness, and the fukui function in the electronic theory of and analysis of expression, 8619 metals and catalysis, 6723 cDNA library screening Catalytic site Modified oligonucleotides as alternatives to the synthesis of mixed Photoaffinity labeling of diphtheria toxin fragment A with NAD: probes for the screening of cDNA libraries, 7510 Structure of the photoproduct at position 148, 7237 cDNA seqnencing Cataract Molecular cloning, cDNA sequencing, and chemical synthesis of cecropin Opacification of y-crystallin solutions from calf lens in relation to cold B from Hyalophora cecropia, 2240 cataract formation, 1701 Cloning and sequencing of cDNA encoding the complete mouse liver The role of ascorbic acid in senile cataract, 7193 alcohol dehydrogenase, 2262 Disulfide bond formation in the eye lens, 7965 Cecropin Ca omine Molecular cloning, cDNA sequencing, and chemical synthesis of cecropin Effects of phorbol ester on catecholamine secretion and protein B from Hyalophora cecropia, 2240 phosphorylation in adrenal medullary cell cultures, 930 2-Adrenergic receptors contribute to catecholamine-stimulated Cel adhesion shortening of action potential duration in dog atrial muscle, 4521 Molecular cloning and sequence analysis of a chondroitin sulfate Endothelial cells from bovine adrenal medula develop capillary-like proteoglycan cDNA, 1321 growth patterns in culture, 4702 A monoclonal antibody disrupting calcium-dependent cell-cell adhesion Changes in plasma proenkephalin peptide F and catecholamine levels of brain tissues: Possible role of its target antigen in animal pattern during graded exercise in men, 6349 formation, 2789 8858 Subject Index Proc. Natl. Acad. Sci. USA 82 (1985)

Characterization of toposomes from sea urchin blastula cells: A cell Cell proliferation organelle mediating cell adhesion and expressing positional Heparin affinity of anionic and cationic capillary endothelial cell growth information, 8062 factors: Analysis of hypothalamus-derived growth factors and Characterization of antigens recognized by monoclonal and polyclonal fibroblast growth factors, 805 antibodies directed against uvomorulin, 8067 Evidence that a 90-kDa phosphoprotein, an associated kinase, and a specific phosphatase are involved in the regulation of Cloudman Cell adhesion molecule melanoma cell proliferation by insulin, 1007 Involvement of the nerve growth factor-inducible large external Growth-dependent expression of multiple species of DNA glycoprotein (NILE) in neurite fasciculation in primary cultures of rat methyltransferase in murine erythroleukemia cells, 2674 brain, 1276 Regulation of c-myc mRNA levels in normal human lymphocytes by Expression sequences of cell adhesion molecules, 6942 modulators of cell proliferation, 4221 Kinetic analysis of regulatory events in G1 leading to proliferation or Cell adhesion molecule, liver quiescence of Swiss 3T3 cells, 5365 Isolation of a cDNA clone for the liver cell adhesion molecule Genes selectively expressed in proliferating Dictyostelium amoebae, (L-CAM), 2809 8540 Cell size Cell adhesion molecule, neural Cell size as a determinant of the clone-forming ability of human Neural cell adhesion molecule (N-CAM) accumulates in denervated and keratinocytes, 5390 paralyzed skeletal muscles, 4544 Chromosomal location of the gene encoding the neural cell adhesion Cell sorting molecule (N-CAM) in the mouse, 7631 Selective loss of a subset of T helper cells in active multiple sclerosis, 7389 Cell-cell communication Reduction of gap junctional conductance by microinjection of antibodies Cell-substrate adhesion molecule against the 27-kDa liver gap junction polypeptide, 2412 Cytotactin, an extracellular matrix protein of neural and non-neural Potential role of the src gene product in inhibition of gap-junctional tissues that mediates glia-neuron interaction, 8075 communication in NIH/3T3 cells, 5360 Cell-substratum interaction Laminin is associated with the "neurite outgrowth-promoting factors" Cell-cell interaction found in conditioned 2183 Expression sequences of cell adhesion molecules, 6942 media, Cell surface antigen Cell-cell junction Cell surface antigen of human neuroblastomas is related to nuclear Phosphotyrosine-containing proteins are concentrated in focal adhesions antigen of normal cells, 6894 and intercellular junctions in normal cells, 6576 Cell volume Cell cloning system Changes in cell volume measured with an electrophysiologic A high-efficiency cloning system for single hapten-specific B lymphocytes technique, 6014 that is suitable for assay of putative growth and differentiation Cell wall, bacterial factors, 3395 Biomechanics of bacterial walls: Studies of bacterial thread made from Cell cycle Bacillus subtilis, 2163 Correlation of ouabain-sensitive ion movements with cell-cycle Centipede activation, 1599 Centipedal hemocyanin: Its structure and its implications for arthropod Expression of a mouse long terminal repeat is cell cycle-linked, 1946 phylogeny, 3721 Cell-cycle dependence and properties of the HeLa cell DNA polymerase system, 2220 Central nervous system Fluctuation of the Ca2+-sequestering activity of permeabilized sea urchin Calcitonin gene-related peptide and its binding sites in the human central embryos during the cell cycle, 2389 nervous system and pituitary, 248 Defective macromolecule biosynthesis and cell-cycle progression in a Differentiating effects of murine nerve growth factor in the peripheral and mammalian cell starved for mevalonate, 3257 central nervous systems of Xenopus laevis tadpoles, 7111 Cell cycle-dependent variations in the distribution of the nuclear protein Two molecular weight forms of muscarinic acetylcholine receptors in the cyclin proliferating cell nuclear antigen in cultured cells: Subdivision of avian central nervous system: Switch in predominant form during S phase, 3262 differentiation of synapses, 8785 Protein kinase activity associated with the product of the yeast cell division cycle gene CDC28, 4055 Centriole Faithful cell-cycle regulation of a recombinant mouse histone H4 gene is A widely distributed nuclear protein immunologically related to the controlled by sequences in the 3'-terminal part of the gene, 4389 microtubule-associated protein MAP1 is associated with the mitotic Cell-cycle-specific genes differentially expressed in human spindle, 1146 leukemias, 4463 Preferential orientation of centrioles toward the heart in endothelial cells Isolation of the gene encoding adenylate cyclase in Saccharomyces of major blood vessels is reestablished after reversal of a cerevisiae, 5060 segment, 3272 c-myc mRNA levels in the cell cycle change in mouse erythroleukemia Microtubule configurations during fertilization, mitosis, and early cells following inducer treatment, 5323 development in the mouse and the requirement for egg Kinetic analysis of regulatory events in G1 leading to proliferation or microtubule-mediated motility during mammalian fertilization, 4152 quiescence of Swiss 3T3 cells, 5365 Expression of cell-cycle-dependent genes in phytohemagglutinin- Cerebellin stimulated human lymphocytes, 5375 Cerebellin: A quantifiable marker for Purkinje cell maturation, 7145 Chromosomal radiosensitivity during the G2 cell-cycle period of skin Cerebellum fibroblasts from individuals with familial cancer, 5400 Calcitonin gene-related peptide and its binding sites in the human central Regulated expression of mammalian histone H4 genes in vivo requires a nervous system and pituitary, 248 trans-acting transcription factor, 5622 Diversity among Purkinje cells in the monkey cerebellum, 7131 A human histone H4 gene exhibits cell cycle-dependent changes in Functional mapping of the human cerebellum with positron emission chromatin structure that correlate with its expression, 7535 tomography, 7462 Three restriction points in the cell cycle of activated murine B lymphocytes, 7681 Cerebral cortex Evidence for widespread effects of noradrenaline on axon terminals in Cell division the rat frontal cortex, 945 Role of the SuIB (FtsZ) protein in division inhibition during the SOS Two types of muscarinic response to acetylcholine in mammalian cortical response in Escherichia coli: FtsZ stabilizes the inhibitor SulA in neurons, 6344 maxicells, 6045 Transient fluorescence in synchronously dividing Escherichia coli, 7599 Cerebrohepatorenal syndrome Peroxisomal organization in normal and cerebrohepatorenal (Zellweger) Cell fusion syndrome fibroblasts, 6556 Use of a replica technique to isolate muscle cell lines defective in expressing the acetylcholine receptor, 124 Cerebroside Neuronal traits of clonal cell lines derived by fusion of dorsal root Phylogenetic dichotomy of nerve glycosphingolipids, 6779 ganglia neurons with neuroblastoma cells, 3499 Cervical tumor Papillomavirus genomes in human cervical tumors: Analysis of their Cell growth transcriptional activity, 5540 Type A transforming growth factor: A bifunctional regulator of cellular growth, 119 CGP-12177 (-)-S-[3H]CGP-12177 and its use to determine the rate constants of Cell growth regulation unlabeled P-adrenergic antagonists, 925 The regulation of DNA synthesis in quiescent lymphocytes by 1-Chain gene cytoplasmic inhibitors, 5160 The I region of the C57BL/10 mouse: Characterization and physical linkage to H-2K of an SB1-like class II pseudogene, 5500 Cell polarity iO,A3, Preferential orientation of centrioles toward the heart in endothelial cells Chalcone oxide of major blood vessels is reestablished after reversal of a Rapid purification of cytosolic epoxide hydrolase from normal and segment, 3272 clofibrate-treated animals by affinity chromatography, 1663 Subject Index Proc. Natl. Acad. Sci. USA 82 (1985) 8859

Channel Chipanzee Channels formed by botulinum, tetanus, and diphtheria toxins in planar Infectious hepatis B virus from cloned DNA of known nucleotide lipid bilayers: Relevance to translocation of proteins across sequence, 891 membranes, 1692 Production of antibody associated with non-A, non-B hepatitis in a The formation of fenestrations and channels by capillary endothelium in chimpanzee lymphoblastoid cell line established by in vitro vitro, 6181 transformation with Epstein-Barr virus, 2138 A truncated immunoglobulin E pseudogene is found in gorilla and man Charge-relay system but not in chimpanzee, 3712 Confirmation of the assignment of the low-field proton resonance of Variation among human 28S ribosomal RNA genes, 7666 serine proteases by using specifically nitrogen-15 labeled enzyme, 7948 Chironoiwusthnmi Charged-group effect to DNA in chromosomes, 7076 Nature of the charged-group effect on the stability of the C-peptide Site-specific carcinogen binding polytene helix, 2349 chl gene Molybdate reduction by Escherichia coli K-12 and its chl mutants, 227 Chargerin Molybdate reduction by Escherichia coli K-12 and its chl mutants Purified hydrophobic proteins, chargerins, are essential for energy 3532 transduction in oxidative phosphorylation, 1331 (Correction), Chlmydomonas reinhardili Chartin RNAs are on the of microtubules: Antibodies Genes for respiratory chain proteins and ribosomal present Analyzing components against chartins, a 16-kilobase-pair DNA species from Chlamydomonas reinhardtii associated proteins from cultured cells, 6581 mitochondria, 3340 Chebyshev polynomial Characterization of monoclonal antibodies against Chlamydomonas The Markoff-DuffiSchaeffer inequalities abstracted, 955 flagellar dyneins by high-resolution protein blotting, 4717 Nonsense mutations in the Chlamydomonas chloroplast gene that codes Chemical switch for the large subunit of ribulosebisphosphate carboxylase/ A mechanism for memory storage insensitive to molecular turnover: A oxygenase, 5460 bistable autophosphorylating kinase, 3055 Chloramphenicol Chemiosmouis Nonheritable resistance to chloramphenicol and other antibiotics induced Evidence for conduction of protons along the interface between water by salicylates and other chemotactic repellents in Escherichia coli and a polar lipid monolayer, 3217 K-12, 8771 Stochastic free energy transduction, 3222 Chloramphenicol acetyltransferase Chemoreception Eukaryotic transient expression system dependent on transcription Oxygen chemoreception by carotid body cells in culture, 1448 factors and regulatory DNA sequences of vaccinia virus, 19 Functional activation of the long terminal repeat of human T-cell Chemosensory recognition leukemia virus type I by a trans-acting factor, 2277 Chemosensory recognition of mouse major histocompatibility types by another species, 4186 Chloramiphenicol acetyltransferase gene Mutations that affect the translation efficiency of Tn9-derived cat gene in Chemotactic peptide Bacillus subtilis, 173 Neutral endopeptidase 24.11 in human neutrophils: Cleavage of Efficient transcription of a protein-coding gene from the RNA chemotactic peptide, 8737 polymerase I promoter in transfected cells, 722 Lens-specific expression of the chloramphenicol acetyltransferase gene Chemotaids promoted by 5' flanking sequences of the murine aA-crystallin gene in Chimeric chemosensory transducers of Escherichia coli, 1326 explanted chicken lens epithelia, 2334 Pertussis toxin inhibition of chemotaxis and the ADP-ribosylation of a Lens-specific expression and developmental regulation of the bacterial membrane protein in a human-mouse hybrid cell line, 2637 chloramphenicol acetyltransferase gene driven by the murine Solubilization of a vectorial transmembrane receptor in functional form: in mice, 7815 Aspartate receptor of chemotaxis, 4891 aA-crystaflin promoter transgenic Endothelial cell-derived chemotactic activity for mouse peritoneal Chloride macrophages and the effects of modified forms of low density Nitrate storage and retrieval in Beta vulgaris: Effects of nitrate and lipoprotein, 5949 chloride on proton gradients in tonoplast vesicles, 3683 Chimeric chemosensory transducers of Escherichia coli Chloride/formate exchange with formic acid recycling: A mechanism of (Correction), 6019 active chloride transport across epithelial membranes, 6362 Cholera toxin inhibits chemotaxis by a cAMP-independent Single anion-selective channels in basolateral membrane of a mammalian mechanism, 7475 tight epithelium, 7791 Homologies between the Salmonella typhimurium CheY protein and Intracellular calcium regulates basolateral potassium channels in a proteins involved in the regulation of chemotaxis, membrane protein chloride-secreting epithelium, 8823 synthesis, and sporulation, 7989 Mechanism of action of the group A streptococcal C5a inactivator, 8144 Chloride permeability Compensatory mutations in receptor function: A reevaluation of the role Cystic fibrosis decreases the apical membrane chloride permeability of of methylation in bacterial chemotaxis, 8364 monolayers cultured from cells of tracheal epithelium, 6167 Nonheritable resistance to chloramphenicol and other antibiotics induced in Escherichia coli Chloride uptake by salicylates and other chemotactic repellents Chloride uptake into cultured airway epithelial cells from cystic fibrosis K-12, 8771 patients and normal individuals, 6677 Chemotherapy Combination of long-acting microcapsules of the D-tryptophan-6 analog of 3-Chlorobenzolc add luteinizing hormone-releasing hormone with chemotherapy: Genes specifying degradation of 3-chlorobenzoic acid in plasmids pAC27 Investigation in the rat prostate cancer model, 2498 and pJP4, 1638 yFluoromethotrexate: Synthesis and biological activity of a potent inhibitor of dihydrofolate reductase with greatly diminished ability to 142-Chloroethyl)-34(tans14-methylcyclohexyl)-1-nitrosourea form poly--glutamates, 2598 06-Alkylguanine-DNA alkyltransferase activity correlates with the In vitro studies of 2,4-dihydroxyphenylalanine, a prodrug targeted against therapeutic response of human rhabdomyosarcoma xenografts to malignant melanoma cells, 2960 1-(2-chloroethyl)-3-(trans-4-methylcyclohexyl)-1-nitrosourea, 2985 D-Tryptophan-6 analog of luteinizing hormone-releasing hormone as a Chlorophyll protective agent against testicular damage caused by cyclophosphamide Light-harvesting chlorophyll a/a-protein: Three-dimensional structure of in baboons, 2975 a reconstituted membrane lattice in negative stain, 386 In vitro studies of 2,4-dihydroxyphenylalanine, a prodrug targeted against Chlorophyll biosynthesis and assembly into chlorophyll-protein malignant melanoma cells (Correction), 6020 complexes in isolated developing chloroplasts, 5370 Chenopod Organization of pigment proteins in the photosystem II complex of the Betaine synthesis in chenopods: Localization in chloroplasts, 3678 cyanobacterium Anacystis nidulans R2, 6903 cheY gene Chlorophyllprotein complex Homologies between the Salmonella typhimurium CheY protein and Chlorophyll biosynthesis and assembly into chlorophyll-protein proteins involved in the regulation of chemotaxis, membrane protein complexes in isolated developing chloroplasts, 5370 synthesis, and sporulation, 7989 Chloroplast Chicken Ochromonas mitochondria contain a specific chloroplast protein, 1456 Complete sequence of the chicken glyceraldehyde-3-phosphate Efficient induction and selection of chIoroplast-encoded dehydrogenase gene, 1628 antibiotic-resistant mutants in Nicotiana, 1485 5-Azacytidine and sodium butyrate induce expression of aromatase in Tandemly repeated nonribosomal DNA sequences in the chloroplast fibroblasts from chickens carrying the henny feathering trait but not genome of an Acetabularia mediterranea strain, 1706 from wild-type chickens, 3005 Pattern analysis of SS rRNA, 2437 Differences in the side-chain metabolism of vitamin D3 between chickens Betaine synthesis in chenopods: Localization in chloroplasts, 3678 and rats, 7485 Chlorophyll biosynthesis and assembly into chlorophyll-protein complexes in isolated developing chloroplasts, 5370 Child development Nonsense mutations in the Chlamydomonas chloroplast gene that codes How infant and mother jointly contribute to developing cognitive for the large subunit of ribulosebisphosphate carboxylase/ competence in the child, 7470 oxygenase, 5460 8860 Subject Index Proc. Natl. Acad. Sci. USA 82 (1985)

Light regulation of the synthesis of the large subunit of Choriogonadotropin ribulose-1,5-bisphosphate carboxylase in peas: Evidence for Expression of human choriogonadotropin in monkey cells using a single translational control, 5690 simian virus 40 vector, 3644 Interspecific chloroplast recombination in a Nicotiana somatic hybrid, 6960 Chorion Nucleotide sequence of an unusual regionally expressed silkmoth chorion Chloroplast coupling factor RNA: Predicted primary and secondary structures of an architectural Investigation of nucleotide binding sites on chloroplast coupling factor 1 protein, 6035 with 3'-O-(4-benzoyl)benzoyl adenosine 5'-triphosphate, 1950 Chorion gene Chloroplast DNA Silkmoth chorion gene families contain patchwork patterns of sequence Tobacco chloroplast tRNALYS(UUU) gene contains a 2.5-kilobase-pair homology, 2814 intron: An open reading frame and a conserved boundary sequence in the intron, 3557 Chorionic viiH Incomplete X chromosome dosage compensation in chorionic villi of Chloroplast gene human placenta, 3390 In vitro expression of chloroplast genes in lysates of higher plant chloroplasts, 3983 Chroinaffin cell DNA supercoiling affects in vitro transcription of two maize chloroplast Effects of phorbol ester on catecholamine secretion and protein genes differently, 4886 phosphorylation in adrenal medullary cell cultures, 930 In vitro expression of chloroplast genes in lysates of higher plant y-Aminobutyric acid receptor channels in adrenal chromaffin cells: A chloroplasts (Correction), 6721 patch-clamp study, 2168 Endothelial cells from bovine adrenal medula develop capillary-like Chloroquine growth patterns in culture, 4702 Susceptibility of human malaria parasites to chloroquine is pH Endothelial cells from bovine adrenal medulla develop capillary-like dependent, 2784 growth patterns in culture (Correction), 7474 Chlorpromazine Neuroleptic drugs attenuate calcium influx and tension development in Chromatin melting rabbit thoracic aorta: Effects of pimozide, penfluridol, chlorpromazine, Differential scanning calorimetry of nuclei reveals the loss of major and haloperidol, 1237 structural features in chromatin by brief nuclease treatment, 2642 Cholecystokinin gene Chromatin spreading Molecular cloning of the human cholecystokinin gene by use of a Electron microscopic visualization of trp operon expression in synthetic probe containing deoxyinosine, 1931 Salmonella typhimurium, 4638 Differential expression of the mouse cholecystokinin gene during brain Chromatin structure and gut development, 5593 Chromatin structure around the c-myc gene in Burkitt lymphomas with Cholera toxin upstream and downstream translocation points, 1984 Cholera toxin inhibits chemotaxis by a cAMP-independent Nucleosome core particles suppress the thermal untwisting of core DNA mechanism, 7475 and adjacent linker DNA, 4653 Formaldehyde-mediated DNA-protein crosslinking: A probe for in vivo Cholesterol chromatin structures, 6470 Detection in extracts of bovine brain of lipophilic complexes of sulfate A human histone H4 gene exhibits cell cycle-dependent changes in esters of cholesterol and #-sitosterol, 2657 chromatin structure that correlate with its expression, 7535 Sterol control of the phosphatidylethanolamine-phosphatidylcholine conversion in the yeast mutant GL7, 5715 Chromatography, microcolumn A defect in cholesterol esterification in Niemann-Pick disease (type C) Femtomole analysis of prostaglandin pharmaceuticals, 8315 patients, 8247 ChromatophorotopAn Cholesterol bIosynthesis Characterization of a pigment-dispersing hormone in eyestalks of the Interferon stimulates cholesterol and phosphatidylcholine synthesis but fiddler crab Uca pugilator, 5319 inhibits cholesterol ester synthesis in HeLa-S3 cells, 2417 Dietary saturated triacylglycerols suppress hepatic low density Chromium lipoprotein receptor activity in the hamster, 4526 Modification of chromium (VI)-induced DNA damage by glutathione and cytochrome P450 in chicken embryo hepatocytes, 6755 Cholesterol ester Unmodified low density lipoprotein causes cholesteryl ester accumulation Chromosome in J774 macrophages, 416 An electrophoretic karyotype for yeast, 3756 Interferon stimulates cholesterol and phosphatidylcholine synthesis but inhibits cholesterol ester synthesis in HeLa-S3 cells, 2417 Chromosome 1 Identification of a single chromosome in the normal human genome Cholesterol metabolism essential for suppression of hamster cell transformation, 570 3-Hydroxy-3-methylglutaryl-coenzyme A reductase is present in The a-spectrin gene is on chromosome 1 in mouse and man, 3790 peroxisomes in normal rat liver cells, 770 Gene mapping and leader polypeptide sequence of human Human genes involved in cholesterol metabolism: Chromosomal mapping glucocerebrosidase: Implications for Gaucher disease, 7101 of the loci for the low density lipoprotein receptor and Molecular cloning and nucleotide sequence of human glucocerebrosidase 3-hydroxy-3-methylglutaryl-coenzyme A reductase with cDNA cDNA, 7289 probes, 8567 Chromosome 2 Choline Human al(III) and a2(V) procollagen genes are located on the long arm Isolation of a somatic-cell mutant defective in phosphatidylserine of chromosome 2, 3385 biosynthesis, 1926 Differential amplification, assembly, and relocation of multiple DNA Choline acetyltransferase sequences in human neuroblastomas and neuroblastoma cell lines, 3761 Choline acetyltransferase and acetylcholine in Xenopus oocytes injected Human apolipoprotein B-100: Cloning, analysis of liver mRNA, and with mRNA from the electric lobe of Torpedo, 608 assignment of the gene to chromosome 2, 8340 Sympathetic neuron density differentially regulates transmitter Chromosome 4 phenotypic expression in culture, 4296 Evolution and organization of the fibrinogen locus on chromosome 4: Cholinergic ventral forebrain grafts into the neocortex improve passive Gene avoidance memory in a rat model of Alzheimer disease, 5227 duplication accompanied by transposition and inversion, 2344 Nerve growth factor promotes cholinergic development in brain striatal Chromosome 5 cultures, 7777 Assignment of the human gene for the glucocorticoid receptor to Cholinergic neuron chromosome 5, 3751 Dissociated cell culture of cholinergic neurons from nucleus basalis of Chromosome 6 Meynert and other basal forebrain nuclei, 6325 Deletion mapping of HLA and chromosome 6p genes, 3741 Cholinergic synapse Purification and partial characterization of a cholinergic neuronal Chromosome 10 differentiation 8795 Human urokinase gene is located on the long arm of chromosome factor, 10, 4448 Chondrocyte Chromosome localization of the gene for human terminal Avian myelocytomatosis virus immortalizes differentiated quail deoxynucleotidyltransferase to region 10q23.-q25, 5836 chondrocytes, 2756 Chromosome 11 Chondrogenesis Linkage map of the short arm of human chromosome 11: Location of the Purification and characterization of two cartilage-inducing factors from genes for catalase, calcitonin, and insulin-like growth factor II, 5064 bovine demineralized bone, 2267 Chromosomal localization of the human Thy-1 gene, 5832 Chondmoltit sulfate Variable numbers of pepsinogen genes are located in the centromeric Animal cell mutants region of human chromosome 11 and determine the high-frequency defective in glycosaminoglycan biosynthesis, 3197 electrophoretic polymorphism, 6240 Chondr sulfate proteoglycan The human Thy-i gene: Structure and chromosomal location, 6657 Molecular cloning and sequence analysis of a chondroitin sulfate Molecular analysis of chromosome 11 deletions in aniridia-Wilms tumor proteoglycan cDNA, 1321 syndrome, 8592 Subject Index Proc. Natl. Acad. Sci. USA 82 (1985)8 8861

Chromosome 12 Assignment of the gene for human DNA polymerase a to the X Nucleotide sequence of cDNA encoding human a2-macroglobulin and chromosome, 5270 assignment of the chromosomal locus, 2282 Microdissection and microcloning of the mouse X chromosome, 5846 The c-myc oncogene is translocated to the involved chromosome 12 in Is human X chromosome inactivation a sex-determining device?, 6947 mouse plasmacytoma, 4212 Regional mapping of the phenylalanine hydroxylase gene and the Chylomicron phenylketonuria locus in the human genome, 6221 Proapolipoprotein A-I conversion kinetics in vivo in human and in rat, 874 Chromosome 13 Assignment of the gene for Wilson disease to chromosome 13: Linkage to Chymotrypshb the esterase D locus, 1819 Alternative view of enzyme reactions, 2225 Inhibition of chymotrypsin by heparin cofactor II, 6431 Chromosome 20 Gene encoding human growth hormone-releasing factor precursor: Chymotrypsn inhibitor Crystal and molecular structure of chymotrypsin inhibitor 2 from barley Structure, sequence, and chromosomal assignment, 63 seeds in complex with subtilisin Novo, 7242 Chromosome 21 Cigarette smoking Analysis of DNA haplotypes suggests a genetic predisposition to trisomy eutral endopeptidase 24.11 in human neutrophils: Cleavage of 21 associated with DNA sequences on chromosome 21, 3360 chemotactic peptide, 8737 Chromosome damage clI protein Chromosomal radiosensitivity during the G2 cell-cycle period of skin A cII-dependent promoter is located within the Q gene of bacteriophage fibroblasts from individuals with familial cancer, 5400 X, 3134 Chromosome deletion Cilia Specific cloning of DNA fragments absent from the DNA of a male Multiple forms of tubulin in the cilia and cytoplasm of Tetrahymena patient with an X chromosome'deletion, 4778 thermophila, 6908 Chromosome inactivation cin gene Is human X chromosome inactivation a sex-determining device?, 6947 Site-specific DNA inversion is enhanced by a DNA sequence element in Chromosome length cis, 3776 Genetic control of chromosome length in yeast, 506 Circadian rhythm Neurochemical basis for the photic control of circadian rhythms and Chromosome, metaphase seasonal reproductive cycles: Role for acetylcholine, 4277 Nick-translation of metaphase chromosomes: In vitro labeling of Identification of a high molecular weight polypeptide that may be part of nuclease-hypersensitive regions in chromosomes, 854 the circadian clockwork in Acetabularia, 6899 Chromosome, minute Circular dichroism Ultrastructural features of minute chromosomes in a Imaging of optically active biological structures by use of circularly methotrexate-resistant mouse 3T3 cell line, 1126 polarized light, 401 Chromosome, Philadelphia Circular dlchroism, magnetic Cell lines and clinical isolates derived from Ph -positive chronic Low-temperature magnetic circular dichroism studies of native laccase: myelogenous leukemia patients express c-abl proteins with a common Spectroscopic evidence for exogenous ligand bridging at a trinuclear structural alteration, 1810 copper active site, 3063 Chromosome polytene Circulatory obstruction Site-specific carcinogen binding to DNA in polytene chromosomes, 7076 Membrane knobs are required for the microcirculatory obstruction Chromosome rearrangement induced by Plasmodiumfalciparum-infected erythrocytes, 3829 Chromosome localization of the gene for human terminal Cirrhosis deoxynucleotidyltransferase to region 10q23-q25, 5836 Abnormal polyunsaturated fatty acid patterns of serum lipids in c-src is consistently conserved in the chromosomal deletion (20q) alcoholism and cirrhosis: Arachidonic acid deficiency in cirrhosis, 1815 observed in myeloid disorders, 6692 Cisplatin Chromosome, telocentric Alkylating agent resistance: In vitro studies with human cell lines, 2158 Construction of telocentric chromosomes in Saccharomyces Sequence-dependent termination of in vitro DNA synthesis by cis- and cerevisiae, 2106 trans-diamminedichloroplatinum(II), 4616 Chromosome transfer Citrate synthase Adult and fetal human globin genes are expressed following chromosomal Characterization of rate-controlling steps in vivo by use of an adjustable transfer into MEL cells, 780 expression vector, 3577 Chromosome trandocation Citrobacterfreundi Isolation and analysis of the 21q+ chromosome in the acute myelogenous Regulatory components in Citrobacterfreundii ampC P-lactamase leukemia 8;21 translocation: Evidence that c-mos is not induction, 4620 translocated, 464 Cell lines and clinical isolates derived from Phi-positive chronic Class I antigen myelogenous leukemia patients express c-abl proteins with a common See also HLA antigen structural alteration, 1810 Human major histocompatibility complex class I antigens: Residues Chromatin structure around the c-myc gene in Burkitt lymphomas with 61-83 of the HLA-B7 heavy chain specify an alloreactive site, 539 upstream and downstream translocation points, 1984 Structure and expression of genes encoding murine Qa-2 class I Activation of the c-myc oncogene by the immunoglobulin heavy-chain antigens, 5920 gene enhancer after multiple switch region-mediated chromosome Mutations that impair a posttranscriptional step in expression of HLA-A rearrangements in a murine plasmacytoma, 3746 and -B antigens, 8183 The c-myc oncogene is translocated to the involved chromosome 12 in Molecular association between major histocompatibility complex class I mouse plasmacytoma, 4212 antigens and insulin receptors in mouse liver membranes, 8634 Gene localization on sorted chromosomes: Definitive evidence on the Claw I gene relative positioning of genes participating in the mouse DNA sequence of the mouse H-2Dd transplantation antigen gene, 1175 plasmacytoma-associated typical translocation, 6975 Mouse major histocompatibility class I gene expression'begins at Translocation of c-myc in the hereditary renal cell carcinoma associated midsomite stage and is inducible in earlier-stage embryos by with a t(3;8)(pl4.2;q24.13) chromosomal translocation, 6980 interferon, 2427 Nucleotide sequence of a t(14;18) chromosomal breakpoint in follicular Expression in L cells of transfected class I genes from the mouse major lymphoma and demonstration of a breakpoint-cluster region near a histocompatibility complex, 5505 transcriptionally active locus on chromosome 18, 7439 Intron sequences reveal evolutionary relationships among major Chromosomal localization and characterization of c-abl in the t(6;9) of histocompatibility complex class I genes, 5860 acute nonlymphocytic leukemia, 8742 Expression of hybrid class I genes of the major histocompatibility Chromosome "walking" complex in mouse L cells, 6245 A 78-kilobase region of mouse chromosome 3 contains salivary and Class H antigen pancreatic amylase genes and a pseudogene, 5446 Two separate functions of class II (Ia) molecules: T-cell stimulation and B-cell excitation, 516 Chromosome X Structural organization of the DR subregion of the human major Tissue-specific levels of human glucose--phosphate dehydrogenase histocompatibility complex, 5165 correlate with methylation of specific sites at the 3' end of the Linkage map of three HLA-DR a-chain genes: Evidence for a recent gene, 1465 duplication event, 7197 The telomeric region of the human X chromosome long arm: Presence of Class H major histocompatibility complex molecules regulate the a highly polymorphic DNA marker and analysis of recombination development of the T4+T8- inducer phenotype of cultured human frequency, 2824 8178 Incomplete X chromosome dosage compensation in chorionic villi of thymocytes, human placenta, 3390 Cliathrin Specific cloning of DNA fragments absent from the DNA of a male Clathrin-immunoreactive sites in the Golgi apparatus are concentrated at patient with an X chromosome deletion, 4778 the trans pole in polypeptide hormone-secreting cells, 5385 8862 Subject Index Prroc. Nadl. Acad. Sci. USA 82 (1985)

Brain clathrin light chain 2 can be phosphorylated by a coated vesicle Colchicine kinase, 8039 Multiply drug-resistant human KB carcinoma cells have decreased amounts of a 75-kDa and a 72-kDa glycoprotein, 2330 Cleavage/packaging signal The herpes simplex virus amplicon: Analyses of cis-acting replication Cold acclimation functions, 694 Altered gene expression during cold acclimation of spinach, 3673 Clock, biological Cold stress Identification of a high molecular weight polypeptide that may be part of Evidence for a role of endogenous corticotropin-releasing factor in cold, the circadian clockwork in Acetabularia, 6899 ether, immobilization, and traumatic stress, 1247 Clock, molecular Cold virus Evidence for higher rates of nucleotide substitution in rodents than in Molecular cloning and complete sequence determination of RNA genome man, 1741 of human rhinovirus type 14, 732 Clofibrate ColEl plasmid Rapid purification of cytosolic epoxide hydrolase from normal and Characterization of the ColEl primer-RNA1 complex: Analysis of a clofibrate-treated animals by affinity chromatography, 1663 domain of ColEl RNA1 necessary for its interaction with primer RNA, 2257 Clonal population structure A population genetic framework for the study of invasive diseases caused Colicin El by serotype b strains of Haemophilus influenzae, 5078 Acidic pH requirement for insertion of colicin El into artificial membrane vesicles: Relevance to the mechanism of action of colicins and certain Clone-forming ability toxins, 1386 Cell size as a determinant of the clone-forming ability of human Structural and functional organization of the colicin El operon, 8389 keratinocytes, 5390 Coagen Clostridiwnisnocuum Differences between two fractions of glycosaminoglycans of the corneal Construction of the mycoplasma evolutionary tree from 5S rRNA stroma in their structural relation to collagen, 760 sequence data, 1160 Purification and characterization of two cartilage-inducing factors from bovine demineralized bone, 2267 Clostridium pasteuianum Avian myelocytomatosis virus immortalizes differentiated quail Cloning and nucleotide sequence determination of the Clostridium chondrocytes, 2756 pasteurianum ferredoxin gene, 1653 Morphogenetic rearrangement of injected collagen in developing chicken limb buds, 2804 Clostridium sticknd Intron-mediated recombination may cause a deletion in an al type I A selenium-containing nucleoside at the first position of the anticodon in collagen chain in a lethal form of osteogenesis imperfecta, 2870 seleno-tRNACHu from Clostridium sticklandii, 347 Phosphorylation of hydroxylysine residues in collagen synthesized by cultured aortic smooth muscle cells, 3091 Clostidiun thermoaceicum Chromosomal assignments of the genes coding for human types II, HI, Evidence that an iron-nickel-carbon complex is formed by reaction of and IV collagen: A dispersed gene family, 3330 CO with the CO dehydrogenase from Clostridium thermo- Human al(III) and a2(V) procollagen genes are located on the long arm aceticum, 6811 of chromosome 2, 3385 Restricted homology between human al type IV and other procollagen Clot chains, 3649 Effects of fibrinogen-binding tetrapeptides on mechanical properties of Supramolecular assemblies of mRNA direct the coordinated synthesis of fine fibrin clots, 1410 type I procollagen chains, 3693 Sustained release of epidermal growth factor accelerates wound Coagulation repair, 7340 See Blood coagulation and Factor Hepatic lipocytes: The principal collagen-producing cells of normal rat Coated pit liver, 8681 Murine interferon-,3 receptor-mediated endocytosis and nuclear Collagen degradation membrane binding, 3281 Autoregulation of collagenase production by a protein synthesized and Coconut cadang cadang viroid secreted by synovial fibroblasts: Cellular mechanism for control of Domains in viroids: Evidence of intermolecular RNA rearrangements and collagen degradation, 1916 their contribution to viroid evolution, 4582 Collagen fibril Codon recognition Synchrotron radiation x-ray scattering in the early stages of in vitro Molecular mechanism of codon recognition by tRNA species with collagen fibril formation, 4693 modified uridine in the first position of the anticodon, 4905 Collagen gene Identification and characterization of the human type II collagen gene Codon usage (COL2AI), 2555 Multiple-alphabet amino acid sequence comparisons of the A distinct class of vertebrate collagen genes encodes chicken type IX imunoglobulin K-chain constant domain, 8597 collagen polypeptides, 4050 Coelenterazine Altered steady-state ratio of type I/HI procollagen mRNAs correlates ATP-dependent bioluminescence in the firefly squid, Watasenia with selectively increased type I procollagen biosynthesis in cultured scintillans, 4629 keloid fibroblasts, 5935 Coenzyme A Collagen-like sequence Activation of retinoic acid by coenzyme A for the formation of ethyl Structure of canine pulmonary surfactant apoprotein: cDNA and retinoate, 6419 complete amino acid sequence, 6379 Coenzyme Qio Collagen substratum Biochemical rationale and myocardial tissue data on the effective therapy Interaction of mouse mammary epithelial cells with collagen substrata: of cardiomyopathy with coenzyme Q1o, 901 Regulation of casein gene expression and secretion, 1419 Response of patients in classes III and IV of cardiomyopathy to therapy Collagen, type II in a blind and crossover trial with coenzyme Qio, 4240 Nonrandom association of a type II procollagen genotype with Biochemical rationale and the cardiac response of patients with muscle achondroplasia, 5465 disease to therapy with coenzyme Qio, 4513 Collagen, type IX Cognition Type IX collagen from sternal cartilage of chicken embryo contains How infant and mother jointly contribute to developing cognitive covalently bound glycosaminoglycans, 2608 competence in the child, 7470 A distinct class of vertebrate collagen genes encodes chicken type IX collagen polypeptides, 4050 Coiled-coil protein Presence of two distinct regions in the coiled-coil structure of the Collagenase streptococcal Pep M5 protein: Relationship to mammalian coiled-coil Autoregulation of collagenase production by a protein synthesized and proteins and implications to its biological properties, 1064 secreted by synovial fibroblasts: Cellular mechanism for control of collagen degradation, 1916 Coke oven worker Stimulation of in vitro human skin collagenase expression by Detection of benzo[a]pyrene diol epoxide-DNA adducts in peripheral platelet-derived growth factor, 4132 blood lymphocytes and antibodies to the adducts in serum from coke oven workers, 6672 Coilagenase inhibitor Platelet-derived collagenase inhibitor: Characterization and subcellular COL gene localization, 2779 Chromosomal assignments of the genes coding for human types H, III, Differentiation of a human leukemia cell line and expression of and IV collagen: A dispersed gene family, 3330 collagenase inhibitor, 5380 COL2A1 gene Colletotkhum lndemuthianum Identification and characterization of the human type II collagen gene Accumulation of hydroxyproline-rich glycoprotein mRNAs in response to (COL2AJ), 2555 fungal elicitor and infection, 6551 Subject Index Proc. Natl. Acad. Sci. USA 82 (1985) 8863

Rapid transient induction of phenylalanine ammonia-lyase mRNA in Complement component C9 elicitor-treated bean cells, 6731 Proteolytic modification of human complement protein C9: Loss of poly(C9) and circular lesion formation without impairment of Collineation, fundamental function, 2128 Harmonic maps of 52 into a complex Grassmann manifold, 2217 Multimeric complement component C9 is necessary for killing of Escherichia coli J5 by terminal attack complex C5b-9, 4808 Colon Enhanced complement-mediated lysis of type HI paroxysmal nocturnal Characterization of Lewis antigens in normal colon and gastrointestinal hemoglobinuria erythrocytes involves increased C9 binding and adenocarcinomas, 3552 polymerization, 5520 Colony-forming unit Purification and biochemical characterization of human pluripotent Complement component Clq hematopoietic colony-stimulating factor, 1526 The Clq subunit of the first component of complement binds to laminin: A mechanism for the deposition and retention of immune complexes in Coony-forming unit, spleen basement membrane, 3824 Failure to demonstrate pluripotential hemopoietic stem cells in mouse brains, 4268 Complement fragment C3a Cardiac dysfunction caused by purified human C3a anaphylatoxin, 886 Colony-stimulating factor Purification and partial amino acid sequence of asialo murine Complement fragment C5a granulocyte-macrophage colony stimulating factor, 292 Chemical synthesis of a gene encoding the human complement fragment Purification and biochemical characterization of human pluripotent C5a and its expression in Escherichia col, 3543 hematopoietic colony-stimulating factor, 1526 Complement fagments C3b/C4b Purification of hemopoietin 1: A multilineage hemopoietic growth Identification of a partial cDNA clone for the human receptor for factor, 2764 7711 Isolation of cDNA for a human granulocyte-macrophage complement fragments C3b/C4b, colony-stimulating factor by functional expression in mammalian Complement receptor cells, 4360 Identification of an additional class of C3-binding membrane proteins of Aminb-terminal amino acid sequence of murine colony-stimulating factor human peripheral blood leukocytes and cell lines, 859 1, 4486 Mapping of the C3d receptor (CR2)-binding site and a ncoantigenic site in Cloning, sequence, and expression of a human granulocyte/macrophage the C3d domain of the third component of complement, 4235 colony-stimulating factor, 6250 Amino-terminal amino acid sequence of murine colony-stimulating factor Complementarity-deternining region 1 (Correction), 7801 Possible involvement of human D minigenes in the first complementarity-determining region of K light chains, 2125 Color Antigen-binding specificities of antibodies are primarily determined by Color categorization: A possible concordance between genes and seven residues of VH, 2945 culture, 5805 Complementary DNA Commelina communis See cDNA Kinetic properties of the blue-light response of stomata, 8019 Complementton Competence Regeneration of active enzyme by formation of hybrids from inactive DNA-damage-inducible (din) loci are transcriptionally activated in derivatives: Implications for active sites shared between polypeptide competent Bacillus subtilis, 6201 chains of aspartate transcarbamoylase, 361 Competence gene family Compressibility Inhibitory effects of interferon on the expression of genes regulated by Molecular and area of lipid bilayers, 6532 platelet-derived growth factor, 7608 packing compressibility Computer Competition The molecular electronic device and the biochip computer: Present Persistence and coexistence of a nonsymbiotic coral in open reef environments, 2432 status, 1874 Complement Concanavalin A Amelioration of lytic abnormalities of paroxysmal nocturnal A 20-kDa protein associated with the murine T-cell antigen receptor is hemoglobinuria with decay-accelerating factor, 2980 -phosphorylated in response to activation by antigen or concanavalin Mechanism of action of the group A streptococcal CSa inactivator, 8144 A, 1969 Complement component C1 Concanavalln A receptor Anti-peripheral myelin antibody in patients with demyelinating Electron microscopic observation of domain movement in reconstituted neuropathy: Quantitative and kinetic determination of serum antibody erythrocyte membranes, 7304 by complement component 1 fixation, 905 Concerted twis Domain structure and associated functions of subcomponents Clr and The primary process of vision and the structure of bathorhodopsin: A Cis of the first component of human complement, 4477 mechanism for photoisomerization of polyenes, 259 Complement component C1 inhibitor Conditioned medium Human plasma kallikrein and C1 inhibitor form a complex possessing an Human leukemia cell maturation induced by a T-cell lymphokine isolated epitope that is not detectable on the parent molecules: Demonstration from medium conditioned by normal lymphocytes, 1209 using a monoclonal antibody, 5190 Laminin is associated with the "neurite outgrowth-promoting factors" Complement component C3 found in conditioned media, 2183 Common evolutionary origin of a2-macroglobulin and complement components C3 and C4, 9 Conformation Human complement component C3: cDNA coding sequence and derived Studies on angiotensin II and analogs: Impact of substitution in position 8 primary structure, 708 on conformation and activity, 1881 Identification of an additional class of C3-binding membrane proteins of Connective tissue human peripheral blood leukocytes and cell lines, 859 Autoregulation of collagenase production by a protein synthesized and gpl4O, the C3d receptor of human B lymphocytes, is also the secreted by synovial fibroblasts: Cellular mechanism for control of Epstein-Barr virus receptor, 1490 collagen degradation, 1916 Mapping of the C3d receptor (CR2)-binding site and a neoantigenic site in the C3d domain of the third component of complement, 4235 Connectivity Complement-dependent cellular cytotoxicity: Lymphoblastoid lines that Topology of bonding in 7r-electron systems, 1 activate complement component 3 (C3) and express C3 receptors have increased sensitivity to lymphocyte-mediated lysis in the presence of Constant fresh human serum, 5470 Constants and pseudo-constants of the Kadomtsev-Petviashvili equation, 5242 Complement component C4 Common evolutionary origin of a2-macroglobulin and complement Contact Inhibition components C3 and C4, 9 A contact-insensitive subpopulation in Syrian hamster cell cultures with a Two genes encoding steroid 21-hydroxylase are located near the genes greater susceptibility to chemically induced neoplastic encoding the fourth component of complement in man, 1089 transformation, 5005 Multiple duplications of complement C4 gene correlate with H-2-controlled testosterone-independent expression of its sex-limited Contrast isoform, C4-Slp, 1746 Contrast and assimilation in the perception of brightness, 5983 Liver mRNA probes disclose two cytochrome P-450 genes duplicated in tandem with the complement C4 loci of the mouse H-2S region, 4453 Control element Complete cDNA sequence of the fourth component of murine Independent control elements that determine yolk protein gene complement, 5895 expression in alternative Drosophila tissues, 13% Complement component C4 gene Controiled release Mapping of steroid 21-hydroxylase genes adjacent to complement Combination of long-acting microcapsules of the D-tryptophan-6 analog of component C4 genes in HLA, the major histocompatibility complex in luteinizing hormone-releasing hormone with chemotherapy: man, 521 Investigation in the rat prostate cancer model, 2498 8864 Subject Index Proc. Natl. Acad. Sci. USA 82 (1985)

Cooperativity Coupling Thermodynamic and kinetic cooperativity in ligand binding to multiple Stochastic free energy transduction, 3222 sites on a protein: Ca2+ activation of an ATP-driven Ca pump, 4688 Experimental resolution of cooperative free energies for the ten ligation Coupling factor 1 states of human hemoglobin, 5347 Subunit stoichiometry and juxtaposition of the photosynthetic coupling factor 1: Immunoelectron microscopy using monoclonal Coordination number antibodies, 7874 Correlation between catalytic activity and bonding and coordination number of atoms and molecules on transition metal surfaces: Theory COX gene and experimental evidence, 2207 Two nonidentical forms of subunit V are functional in yeast cytochrome c oxidase, 2235 Copepod Experimental transmission of a microsporidian pathogen from mosquitoes Coxsackie B3 virus to an alternate copepod host, 5574 Molecular cloning of the genome of a cardiotropic Coxsackie B3 virus: Full-length reverse-transcribed recombinant cDNA generates infectious Copper virus in mammalian cells, 4818 Low-temperature magnetic circular dichroism studies of native laccase: Spectroscopic evidence for exogenous ligand bridging at a trinuclear CpG dinucleotide copper active site, 3063 Incomplete X chromosome dosage compensation in chorionic villi of human placenta, 3390 Copper metabolism Assignment of the gene for Wilson disease to chromosome 13: Linkage to Crab the esterase D locus, 1819 Characterization of a pigment-dispersing hormone in eyestalks of the fiddler crab Uca pugilator, 5319 protein CojpperSimultaneous comparison of three protein sequences, 3073 Crack Fracture dynamics of fusion of two anti-plane cracks, 1869 Copy number control Plasmid pT181 replication is regulated by two countertranscripts, 638 Crayfish Protein RepC is involved in copy number control of the broad host range Quantal mechanism of long-term synaptic potentiation, 5978 plasmid RSF1010, 6090 Creatine kinase Coral Two tissue-specific isozymes of creatine kinase have closely matched Persistence and coexistence of a nonsymbiotic coral in open reef amino acid sequences, 2310 environments, 2432 Cryobaroenzymic studies as a tool for investigating activated complexes: Creatine kinaseADP-Mgnitrate-creatine as a model, 7495 Coresiduality Complete nucleotide sequence of dog heart creatine kinase mRNA: Topology of bonding in ir-electron systems, 1 Conservation of amino acid sequence within and among species, 8394 Cornea Creutzfeldt-Jakob disease Differences between two fractions of glycosaminoglycans of the corneal Scrapie and Creutzfeldt-Jakob disease prion proteins share physical stroma in their structural relation to collagen, 760 properties and antigenic determinants, 997 The 200- and 150-kDa neurofilament proteins react with IgG Cortex, cerebral autoantibodies from patients with kuru, Creutzfeldt-Jakob disease, and Cortical anomalies in brains of New Zealand mice: A neuropathologic other neurologic diseases, 3485 model of dyslexia?, 8072 The 200- and 150-kDa neurofilament proteins react with IgG autoantibodies from chimpanzees with kuru or Creutzfeldt-Jakob Cortical organization disease; A 62-kDa neurofilament-associated protein reacts with sera Model of cortical organization embodying a basis for a theory of from sheep with natural scrapie, 3894 information processing and memory recall, 2364 Specific proteins associated with Creutzfeldt-Jakob disease and scrapie Corticosteroid share antigenic and carbohydrate determinants, 4263 Depletion of mucosal mast cell protease by corticosteroids: Effect on Cricket intestinal anaphylaxis in the rat, 1214 Dendritic sprouting and compensatory synaptogenesis in an identified Corticotropin interneuron follow auditory deprivation in a cricket, 7772 Inhibitors of the cytochrome P450 enzymes block the secretagogue-induced release of corticotropin in mouse pituitary tumor cro gene cells, 1012 Altered Cro repressors from engineered mutagenesis of a synthetic cro Lithium induces corticotropin secretion and desensitization in cultured gene, 1084 anterior pituitary cells, 1286 Crossbridge The influence of mevinolin on the adrenal cortical response to ADP dissociation from actomyosin subfragment 1 is sufficiently slow to corticotropin in heterozygous familial hypercholesterolemia, 6291 in vertebrate 658 Hormone secretagogues increase cytosolic calcium by increasing cAMP limit the unloaded shortening velocity muscle, in corticotropin-secreting cells, 8034 Crossing-over Corticotropin releasing-factor-induced adrenocorticotropin hormone Genetic rearrangement of DNA induces knots with a unique topology: release and synthesis is blocked by incorporation of the inhibitor of Implications for the mechanism of synapsis and crossing-over, 3124 cyclic AMP-dependent protein kinase into anterior pituitary tumor cells by liposomes, 8261 Crosslink Synchrotron radiation x-ray scattering in the early stages of in vitro Corticotropin receptor fibril 4693 Similarity between the corticotropin (ACTH) receptor and a peptide collagen formation, encoded by an RNA that is complementary to ACTH mRNA, 1372 Crosslinking reagent Corticotropin-releasing factor Stabilization of a primary loop in myosin subfragment 1 with a Evidence for a role of endogenous corticotropin-releasing factor in cold, fluorescent crosslinker, 1658 ether, immobilization, and traumatic stress, 1247 Crown gall Ultrashort-loop positive feedback of corticotropin (ACTH)-releasing T-DNA border sequences required for crown gall tumorigenesis, 5112 factor to enhance ACTH release in stress, 3528 Effects of intravenous and intraventricular injection of antisera directed Cruciform structure agalnst corticotropin-releasing factor on the secretion of anterior Partial purification of an enzyme from Saccharomyces cerevisiae that pituitary hormones, 7787 cleaves Holliday junctions, 7247 Corticotropin releasing-factor-induced adrenocorticotropin hormone release and synthesis is blocked by incorporation of the inhibitor of Cryobaroenzymology cyclic AMP-dependent protein kinase into anterior pituitary tumor cells Cryobaroenzymic studies as a tool for investigating activated complexes: by liposomes, 8261 Creatine kinaseADPMg-nitratecreatine as a model, 7495 Isolation and amino acid sequence of corticotropin-releasing factor from pig hypothalami, 8762 Cryptochrome Modified cryptochrome in vivo absorption in dim photosporulation Cosmid mutants of Trichoderma, 2736 A cosmid for selecting genes by complementation in Aspergillus nidulans: Selection of the developmentally regulated yA locus, 834 Crystal growth Efficient cloning of single-copy genes using specialized cosmid vectors: Interactions between acidic proteins and crystals: Stereochemical Isolation of mutant dihydrofolate reductase genes, 1189 requirements in biomineralization, 4110 A cosmid vector that facilitates restriction enzyme mapping, 3159 A highly polymorphic locus in human DNA revealed by cosmid-derived Crystal structure probes, 6206 Electronegativity and hardness as coordinates in structure stability diagrams, 264 Counterion Influence of solvent accessibility and intermolecular contacts on atomic Molecular dynamics simulations of d(C-G-C-G-A)-d(T-C-G-C-G) with and mobilities in hemerythrins, 1104 without "hydrated" counterions, 755 Crystallin Countertranscript Purification of neutral lens endopeptidase: Close similarity to a neutral Plasmid pT181 replication is regulated by two countertranscripts, 638 proteinase in pituitary, 7545 Subject Index Proc. Natl. Acad. Sci. USA 82 (1985) 8865

Lens-specific expression and developmental regulation of the bacterial Hormone secretagogues increase cytosolic calcium by increasing cAMP chloramphenicol acetyltransferase gene driven by the murine in corticotropin-secreting cells, 8034 aA-crystallin promoter in transgenic mice, 7815 Cyclic GMP analog a-Crystalln Interaction of hydrolysis-resistant analogs of cyclic GMP with the cAMP-dependent phosphorylation of bovine lens a-crystallin, 4712 phosphodiesterase and light-sensitive channel of retinal rod outer Antiserum to lens antigens immunostains Muller glia cells in the neural segments, 8813 retina, 5570 Cyclic GMP phosphodiesterase rCrystallin cDNA-derived amino acid sequence of the y subunit of GTPase from Opacification of y-crystallin solutions from calf lens in relation to cold bovine rod outer segments, 1936 cataract formation, 1701 Cyclic nucleotide phosphodiesterase a-Crystalln gene Differential regulation of bovine brain calmodulin-dependent cyclic Lens-specific expression of the chloramphenicol acetyltransferase gene nucleotide phosphodiesterase isozymes by cyclic AMP-dependent promoted by 5' flanking sequences of the murine aA-crystallin gene in protein kinase and calmodulin-dependent phosphatase, 2603 explanted chicken lens epithelia, 2334 Complete structure of the aB-crystallin gene: Conservation of the 2',3'-Cyclic phosphate exon-intron distribution in the two nonlinked a-crystallin genes, 5819 Isolation and characterization of an RNA ligase from HeLa cells, 684 Cucumber Cyclin Purification and characterization of polynucleotide phosphorylase from Cell cycle-dependent variations in the distribution of the nuclear protein cucumber, 1311 cyclin proliferating cell nuclear antigen in cultured cells: Subdivision of S phase, 3262 Cucumber green mottle mosaic virus Elongation in the major direction of tobacco mosaic virus assembly, 3631 Cyclization Total synthesis of (±)-lla-hydroxyprogesterone by cyclization of a Cucumber mosaic virus 1879 Purification and characterization of polynucleotide phosphorylase from polyunsaturated epoxide, cucumber, 1311 Cyclophosphamide Cucumovirus D-Tryptophan-6 analog of luteinizing hormone-releasing hormone as a Nucleotide sequence of the satellite of peanut stunt virus reveals protective agent against testicular damage caused by cyclophosphamide structural homologies with viroids and certain nuclear and m baboons, 2975 mitochondrial introns, 3110 Cyclosporine Cucurbita pepo Intravenous cyclosporine activates afferent and efferent renal nerves and Active auxin uptake by zucchini membrane vesicles: Quantitation using causes sodium retention in innervated kidneys in rats, 8222 ESR volume and ApH determinations, 6541 Cycloxygenase Culture Inhibitors of the cytochrome P450 enzymes block the Outlining social physics for modern societies-locating culture, secretagogue-induced release of corticotropin in mouse pituitary tumor economics, and politics: The Enlightenment reconsidered, 5582 cells, 1012 Color categorization: A possible concordance between genes and culture, 5805 CYRI gene Gene-culture coevolution: Models for the evolution of altruism with Isolation of the gene encoding adenylate cyclase in Saccharomyces 5814 cerevisiae, 5060 cultural transmission, Reconstitution of the GTP-dependent adenylate cyclase from products of Curvature hypothesis the yeast CYR] and RAS2 genes in Escherichia coli, 7855 Intrinsic curvature hypothesis for biomembrane lipid composition: A role for nonbilayer lipids, 3665 Cysteine Argininosuccinate synthetase: Essential role of cysteine and arginine cya gene residues in relation to structure and mechanism of ATP Translational efficiency of the Escherichia coli adenylate cyclase gene: activation, 6745 Mutating the UUG initiation codon to GUG or AUG results in Mapping the cysteine residues and actin-binding regions of villin by using increased gene expression, 5656 antisera to the amino and carboxyl termini of the molecule, 6788 Cyanelle Cysteinylnaphthalene Molecular cloning and nucleotide sequence of the a and 8 subunits of Catabolism of premercapturic acid pathway metabolites of naphthalene to allophycocyanin from the cyanelle genome of Cyanophora naphthols and methylthio-containing metabolites in rats, 668 paradoxa, 3242 Cystic fibrosis Cyanobacterium Cystic fibrosis decreases the apical membrane chloride permeability of Expression and assembly of active cyanobacterial ribulose-1,5- monolayers cultured from cells of tracheal epithelium, 6167 bisphosphate carboxylase/oxygenase in Escherichia coli containing Chloride uptake into cultured airway epithelial cells from cystic fibrosis stoichiometric amounts of large and small subunits, 6100 patients and normal individuals, 6677 Cyanophora paradoxa Cytochalasin B Molecular cloning and nucleotide sequence of the a and i subunits of Glucose transport protein is structurally and immunologically related to allophycocyanin from the cyanelle genome of Cyanophora band 3 and senescent cell antigen, 1731 paradoxa, 3242 Cytochrome c CYCI gene Analysis of an evolutionarily conserved antigenic site on mammalian A synthetic HIS4 regulatory element confers general amino acid control cytochrome c using synthetic peptides, 1508 on the cytochrome c gene (CYCI) of yeast, 498 Developmental expression of nuclear genes that encode mitochondrial Each of three "TATA elements" specifies a subset of the transcription proteins: Insect cytochromes c, 1964 initiation sites at the CYC-I promoter of Saccharomyces H NMR studies of electron exchange rate of Pseudomonas aeruginosa cerevisiae, 8562 azurin, 2039 CYC7 gene Semisynthesis of horse heart cytochrome c analogues from two or three Activation regions in a yeast transposon have homology to mating type fragments, 8279 5423 control sequences and to mammalian enhancers, Cytochrome c gene Cyclase A synthetic HIS4 regulatory element confers general amino acid control Cyclization of RNA 3'-terminal phosphate by cyclase from HeLa cells on the cytochrome c gene (CYCI) of yeast, 498 formation of N(3')pp(5')A activated intermediate, 1316 proceeds via Cytochrome c oxidase Cyclic AMP Two nonidentical forms of subunit V are functional in yeast cytochrome Genetic analysis of 3-adrenergic receptor internalization and c oxidase, 2235 down-regulation, 129 Direct measurement of the electrogenic activity of o-type cytochrome Extensive but reversible depletion of ATP via adenylate cyclase in rat oxidase from Escherichia coli reconstituted into planar lipid adipocytes, 1614 bilayers, 2570 Associative conditioning analog selectively increases cAMP levels of tail Genes for respiratory chain proteins and ribosomal RNAs are present on sensory neurons in Aplysia, 2548 a 16-kilobase-pair DNA species from Chlamydomonas reinhardtii The rate-determining step in cAMP-mediated exocytosis in the rat parotid mitochondria, 3340 and submandibular glands appears to involve analogous 26-kDa integral Differential expression of mitochondrial genes between life cycle stages membrane phosphoproteins, 3237 of Trypanosoma brucei, 3380 Inactivation of S-adenosyl-L-homocysteine hydrolase by cAMP results Kinetics of redox-linked proton pumping activity of native and subunit from dissociation of enzyme-bound NAD+, 4578 HI-depleted cytochrome c oxidase: A stopped-flow investigation, 4876 Gene expression and cAMP, 4606 Incorporation of beef heart cytochrome c oxidase as a proton-motive Genetic dissection of Drosophila adenylate cyclase, 5992 force-generating mechanism in bacterial membrane vesicles, 7555 Acetylcholine and phorbol esters inhibit potassium currents evoked by adenosine and cAMP in Xenopus oocytes, 6001 Cytochromef Cholera toxin inhibits chemotaxis by a cAMP-independent Binding of pea cytochrome f to the inner membrane of Escherichia coli mechanism, 7475 requires the bacterial secA gene product, 7955 8866 Subject Index Proc. Natl. Acad. Sci. USA 82 (1985)

Cytochrome P-450 Paired helical filaments from Alzheimer disease patients contain Mapping of steroid 21-hydroxylase genes adjacent to complement cytoskeletal components, 3916 component C4 genes in HLA, the major histocompatibility complex in Microtubule-associated protein 1B: Identification of a major component man, 521 of the neuronal cytoskeleton, 5404 Isolation and sequence of a human cytochrome P-450 cDNA clone, 983 Remarkable homology among the internal repeats of erythroid and Inhibitors of the cytochrome P-450 enzymes block the nonerythroid spectrin, 5671 secretagogue-induced release of corticotropin in mouse pituitary tumor Visualization of the protein associations in the erythrocyte membrane cells, 1012 skeleton, 6153 Two genes encoding steroid 21-hydroxylase are located near the genes Mapping the cysteine residues and actin-binding regions of villin by using encoding the fourth component of complement in man, 1089 antisera to the amino and carboxyl termini of the molecule, 6788 Sex-dependent expression of mouse testosterone 16a-hydroxylase A muscle-type tropomyosin in human fibroblasts: Evidence for (cytochrome P45016j,): cDNA cloning and pretranslational expression by an alternative RNA splicing mechanism, 7835 regulation, 2024 Identification of a distinct soluble subunit of an intermediate filament Identification and functional characterization of leukotriene B4 protein: Tetrameric vimentin from living cells, 7929 20-hydroxylase of human polymorphonuclear leukocytes, 2292 Cytochrome P450 metabolic activity in embryonic and extraembryonic Cytotactin tissue lineages of mouse embryos, 3311 Cytotactin, an extracellular matrix protein of neural and non-neural Immunochemical evidence for induction of the alcohol-oxidizing tissues that mediates glia-neuron interaction, 8075 cytochrome P-450 of rabbit liver microsomes by diverse agents: Ethanol, imidazole, trichloroethylene, acetone, pyrazole, and Cytotoxic T cell isoniazid, 4065 Rearrangement and transcription of a T-cell receptor P-chain gene in Kinetics of carbon monoxide binding to phenobarbital-induced different T-cell subsets, 531 cytochrome P-450 from rat liver microsomes: A simple bimolecular Cyotoit process, 4900 Strong antitumor activities of IgG3 antibodies to a human Cloning and characterization of cDNAs encoding 2,3,7,8-tetra- melanoma-associated ganglioside, 1499 chlorodibenzo-p-dioxin-inducible rabbit mRNAs for cytochrome PA450 Generation and regulation of autocytotoxicity in mixed lymphocyte isozymes 4 and 6, 5310 cultures: Evidence for active of 4508 Identification of an inducible form of cytochrome P-450 in human suppression autocytotoxic cells, liver, 6310 Cytotoin Genetic differences in oxygen toxicity are correlated with cytochrome Use of monoclonal antibodies to a human cytotoxin for its isolation and P450 inducibility, 6315 for the self-induction of resistance to this 3814 Modification of chromium (VI)-induced DNA damage by glutathione and examining protein, cytochrome P-450 in chicken embryo hepatocytes, 6755 dam gene Nucleotide sequence of the Dpn II DNA methylase gene of Cytochrome P.450 gene Streptococcus pneumoniae and its relationship to the dam gene of Liver mRNA probes disclose two cytochrome P-450 genes duplicated in Escherichia 4468 tandem with the complement C4 loci of the mouse H-2S region, 4453 coli, Cytokeratin Dansylated estramustine Differential expression of intermediate filament proteins distinguishes Dansylated estramustine, a fluorescent probe for studies of estramustine classic from variant small-cell lung cancer cell lines, 4409 uptake and identification of intracellular targets, 8483 Cytokeratin endo A gene Daphxsa nowg One gene and one pseudogene for the cytokeratin endo A, 1155 Changes m 22Na influx and outflux in Daphnia magna (Straus) as a Expression of the cytokeratin endo A gene during early mouse function of elevated Al concentrations in soft water at low pH, 7345 embryogenesis, 8535 Dasydadaceae Cytokinin Tandemly repeated nonribosomal DNA sequences in the chloroplast Presence and source of free isopentenyladenosine in yeasts, 1113 genome of an Acetabularia mediterranea strain, 1706 Cytolysis Dasyurus Wivernnus Xeno eneic antiserum to soluble products from activated lymphoid cells Cloning and chromosomal location of the a- and P-globin genes from a inhibits interleukin 1-mediated functions in the helper pathway of marsupial, 8105 cytolytic-effector-cell differentiation, 1513 Lack of lymphocyte-induced DNA fragmentation in human targets during Daudi cell lysis represents a species-specific difference between human and Interferon regulates c-myc gene expression in Daudi cells at the murine cells, 4482 post-transcriptional level, 1151 Complement-dependent cellular cytotoxicity: Lymphoblastoid lines that activate complement component 3 (C3) and express C3 receptors have d(C-G-C-G-A)-d(T-C-G-C-G) increased sensitivity to lymphocyte-mediated lysis in the presence of Molecular dynamics simulations of d(C-G-C-G-A)-d(T-C-G-C-G) with and fresh human serum, 5470 without "hydrated" counterions, 755 Interleukin 2 promotes growth and cytolytic activity in human T3+4-8- thymocytes, 6268 DC subregion Isolation and biochemical and functional characterization of perforin 1 Gene organization of DC and DX subregions of the human major from cytolytic T-cell granules, 8629 histocompatibility complex, 3410 Heteroantibody duplexes target cells for lysis by cytotoxic T 3-Dedenosne lymphocytes, 8648 3-Deazaadenosine-induced disorganization of macrophage Cytomegalovirus microfilaments, 4060 Precise localization of genes on large animal virus genomes: Use of Xgtll and monoclonal antibodies to map the gene for a cytomegalovirus Decay-accelerating factor protein family, 1266 Amelioration of lytic abnormalities of paroxysmal nocturnal Metabolic activation of the nucleoside analog 9-{[2-hydroxy-1- hemoglobinuria with decay-accelerating factor, 2980 (hydroxymethyl)ethoxy]methyl}guanine in human diploid fibroblasts Decddual tisaue infected with human cytomegalovirus, 2473 and characterization of a hormone A long and complex enhancer activates transcription of the gene coding Identification partial prolactin-like for the highly abundant immediate early mRNA in murine produced by rat decidual tissue, 217 cytomegalovirus, 8325 Decomposition Cytopathic effect Solution of the embedding problem and decomposition of symmetric Characterization of a continuous T-cell line susceptible to the cytopathic matrices, 2197 effects of the acquired immunodeficiency syndrome (AIDS)-associated Dehydro-exo-brevicomin retrovirus, 4539 Synthetic pheromones that promote inter-male aggression in mice, 2059 Cytoplasmic inheritance Efficient induction and selection of chloroplast-encoded Deletion, chromosomal antibiotic-resistant mutants in Nicotiana, 1485 Construction of telocentric chromosomes in Saccharomyces cerevisiae, 2106 Cytoplasmic male sterility Maize mitochondria synthesize organ-specific polypeptides, 6879 Deletion mapping. Deletion mapping of HLA and chromosome 6p genes, 3741 Cytoplasmic matrix The cytoplasmic matrix: Its volume and surface area and the diffusion of Deletion mutation molecules through it, 5030 Intron-mediated recombination may cause a deletion in an al type I collagen chain in a lethal form of osteogenesis imperfecta, 2870 Cytoslne Generation of a dominant 8-MDa deletion at the left terminus of vaccinia Endonuclease-resistant apyrimidinic sites formed by neocarzinostatin at virus DNA, 3365 cytosine residues in DNA: Evidence for a possible role in Immunoglobulin gene rearrangements and deletions in human mutagenesis, 3182 Epstein-Barr virus-transformed cell lines producing different IgG and Cytoskeleton IgA subclasses, 5495 A widely distributed nuclear protein immunologically related to the microtubule-associated protein MAPi is associated with the mitotic Dementia, senile spindle, 1146 Aberrant neurofilament phosphorylation in Alzheimer disease, 4274 Subject Index Proc. Nadl. Acad. Sci. USA 82 (1985) 8867

Demyelinating neuropathy Use of pooled DNA samples to detect linkage disequilibrium of Anti-peripheral myelin antibody in patients with demyelinating polymorphic restriction fragments and human disease: Studies of the neuropathy: Quantitative and kinetic determination of serum antibody HLA class II loci, 6970 by complement component 1 fixation, 905 Activated and unactivated forms of human erythrocyte aldose reductase, 7222 Dendrite Experimental diabetic neuropathy: Impairment of slow transport with Signal enhancement in distal cortical dendrites by means of interactions changes in axon cross-sectional area, 7716 between active dendritic spines, 2192 Prevention of type I diabetes in nonobese diabetic mice by allogeneic Dendritic cell bone marrow transplantation, 7743 Identification of a unique B-cell-stimulating factor produced by a cloned Polymorphic restriction endonuclease sites linked to the HLA-DRa gene: dendritic cell, 183 Localization and use as genetic markers of insulin-dependent Influence of dendritic cells on tumor growth, 4495 diabetes, 8100 Properties of memory T lymphocytes isolated from the mixed leukocyte Hyperglycemia-induced teratogenesis is mediated by a functional reaction, 7686 deficiency of arachidonic acid, 8227 Denervation Diabetogenic activity Neural cell adhesion molecule (N-CAM) accumulates in denervated and Biosynthetic 20-kilodalton methionyl-human growth hormone has paralyzed skeletal muscles, 4544 diabetogenic and insulin-like activities, 4250 denV gene 2,3-D y amne 1-phosphate Expression of a cloned denV gene of bacteriophage T4 in Escherichia Macrophe activation by monosaccharide precursors of Escherichia coli coli, 4763 lipid A, 282 Genetic complementation of UV-induced DNA repair in Chinese hamster Diacyigycerol ovary cells by the denV gene of phage T4, 7656 Diacylglycerols mimic phorbol diester induction of leukemic cell differentiation, 815 2V-Deoxyadenosine Role of protein kinase C in diacylglycerol-mediated induction of ornithine Inactivation of S-adenosyl-L-homocysteine hydrolase by cAMP results decarboxylase and reduction of epidermal growth factor binding, 1941 from dissociation of enzyme-bound NADI, 4578 Ionic responses rapidly elicited by activation of protein kinase C in 2-Deoxyglucose quiescent Swiss 3T3 cells, 2384 Stimulation of glucose uptake by transforming growth factor ,: Evidence 1,2-Diacylglycerol and phorbol ester inhibit agonist-induced formation of for the requirement of epidermal growth factor-receptor inositol phosphates in human platelets: Possible implications for activation, 1346 negative feedback regulation of inositol phospholipid hydrolysis, 2623 Characterization of pituitary calcium-activated, phospholipid-dependent Deoxynosne protein kinase: Redistribution by gonadotropin-releasing hormone, 8203 Molecular cloning of the human cholecystokinin gene by use of a Inhibition of gonadotropin-induced granulosa cell differentiation by synthetic probe containing deoxyinosine, 1931 activation of protein kinase C, 8518 Deoxyribonuclease Diakdema aiirum Nick-translation of metaphase chromosomes: In vitro labeling of Nerves in the spine of a sea urchin: A neglected division of the nuclease-hypersensitive regions in chromosomes, 854 echinoderm nervous system, 1555 A method for mapping intranuclear protein-DNA interactions and its application to a nuclease hypersensitive site, 2296 Diamminedichloroplatinum(il) Alkylating agent resistance: In vitro studies with human cell lines, 2158 Deoxyribonucease I hypersensitivity Sequence-dependent termination of in vitro DNA synthesis by cis- and Regulation of expression of the human interferon y gene, 8173 trans-diamminedichloroplatinum(ll), 4616 Desmoplakin Diazepam Isolation of the non-glycosylated proteins of desmosomes and y-Aminobutyric acid receptor channels in adrenal chromaffin cells: A immunolocalization of a third plaque protein: Desmoplakin m, 810 patch-clamp study, 2168 Desmosome Dibromobimane Isolation of the non-glycosylated proteins of desmosomes and Stabilization of a primary loop in myosin subfragment 1 with a immunolocalization of a third plaque protein: Desmoplakin m, 810 fluorescent crosslinker, 1658 Detergent, nonionic Dichrolsm Anomalous interaction of the acetylcholine receptor protein with the Visualization of oriented hemoglobin S in individual erythrocytes by nonionic detergent Triton X-114, 958 differential extinction-of polarized light, 6527 Deuterostome Dicyostelium Phylogenetic dichotomy of nerve glycosphingolipids, 6779 Genes selectively expressed in proliferating Dictyostelium amoebae, 8540 Development Dictyostelum discoideum See also Differentiation and Morphogenesis mRNA stabilization controls the expression of a class of developmentally Adolescence in Tetrahymena thermophila, 436 regulated genes in Dictyostelium discoideum, 5786 Cloned cDNA for rabbit erythrocyte carbonic anhydrase I: A novel Cloning and characterization of a nonmuscle myosin heavy chain erythrocyte-specific probe to study development in erythroid cDNA, 6807 tissues, 663 Regulated expression of ras gene constructs in Dictyostelium Developmentally regulated expression of a chicken muscle-specific gene transformants, 7005 in stably transfected rat myogenic cells, 3106 Developmentally regulated expression of a chicken muscle-specific gene Dcclohexycarbodlmlde in rat cells Mechanism of inhibition of mitochondrial adenosine triphosphatase by stably transfected myogenic (Correction), 5578 dicyclohexylcarbodiimide and oligomycin: Relationship to ATP Development, neural synthesis, 1589 Cerebellin: A quantifiable marker for Purkinje cell maturation, 7145 D~~ddslcar~mladein protein Dexamethasone sequence of Fo-ATase proteolipid (subunit 9) gene of maize Gene expression during terminal differentiation: Dexamethasone mitochondria, 1015 suppression of inducer-mediated al- and p"w-globin gene 7,8-Dldemethyl4-hydroxy-5-deazaflavin expression, 5020 Stereochemical studies of a selenium-containing hydrogenase from Dexamethasone 21-methanesuffonate Methanococcus vannielii: Determination of the absolute configuration Identification of Yb-glutathione-S-transferase as a major rat liver protein of C-5 chirally labeled dihydro-8-hydroxy-5-deazaflavin cofactor, 1364 labeled with dexamethasone 21-methanesulfonate, 7165 Dideox DNA sequencing Diabetes A fidelity assay using "dideoxy" DNA sequencing: A measurement of Correction of hyperglycemia with phloridzin restores the glucagon sequence dependence and frequency of forming 5-bromouracil guanine response to glucose in insulin-deficient dogs: Implications for human base mispairs, 1301 diabetes, 1544 High glucose concentrations partially release hexokinase from inhibition Diet by glucose 6-phosphate, 1552 Efficiency of utilization of various sources of energy for growth, 4866 Capillary number and percentage closed in human diabetic sural Diethyl pyrocarbonate nerve, 2513 Diethyl pyrocarbonate: A chemical probe for secondary structure in Increased activity of the glucose cycle in the liver: Early characteristic of negatively supercoiled DNA, 8009 type 2 diabetes, 2965 A systematic study of HLA class H-P DNA restriction fragments in Differentiation insulin-dependent diabetes mellitus, 3335 See also Development and Morphogenesis Insulin-related genes expressed in human placenta from normal and Expression of the mouse serum albumin gene introduced into _ diabetic pregnancies, 3868 erentiated and dedifferentiated rat hepatoma cells, 765 Predominance of hemodynamic rather than metabolic factors in the Diacylglycerols mimic phorbol diester induction of leukemic cell pathogenesis of diabetic glomerulopathy, 5963 differentiation, 815 In vivo prevention of thyroid and pancreatic autoimmunity in the BB rat An initiator of carcinogenesis selectively and stably inhibits stem cell by antibody to class II major histocompatibility complex gene differentiation: A concept that initiation of carcinogenesis involves products, 6627 multiple phases, 2995 8868 Subject Index Proc. Natl. Acad. Sci. USA 82 (1985)

Maintenance of differentiated rat hepatocytes in primary culture, 3252 din gene Differentiation of a human leukemia cell line and expression of DNA-damage-inducible (din) loci are transcriptionally activated in collagenase inhibitor, 5380 competent Bacillus subtilis, 6201 Differentiation antigen Diphtheria toxin Specificity analysis of mouse monoclonal antibodies defining cell surface Channels formed by botulinum, tetanus, and diphtheria toxins in planar antigens of human renal cancer, 2955 lipid bilayers: Relevance to translocation of proteins across Specificity analysis of mouse monoclonal antibodies defining cell surface membranes, 1692 antigens of human renal cancer (Correction), 5236 Photoaffinity Labeling of diphtheria toxin fragment A with NAD: Structure of the photoproduct at position 148, 7237 Differentiation factor B-cell growth factor (B-cell growth factor I or B-cell-stimulating factor, Direct repeat sequence provisional 1) is a differentiation factor for resting B cells and may not Mutations in direct repeat sequences and in a conserved sequence induce cell growth, 2465 adjacent to the repeats result in a defective replication origin in plasmid R6K, 1480 Differentiation, nerve Differentiation of catecholaminergic cells in cultures of embryonic avian Disorder sensory ganglia, 8800 A model of protein conformational substates, 3670 Differentiation, neuronal Displacment reacton Differential expression of distinct microtubule-associated proteins during Driving force and nucleophilicity in SN2 displacements, 8288 brain development, 6006 Disodatfionconstant Differentiation, terninal (-)-S-[3HJCGP-12177 and its use to determine the rate constants of Gene expression during terminal differentiation: Dexamethasone unlabeled P-adrenergic antagonists, 925 suppression of inducer-mediated a,- and ,BW-globin gene expression, 5020 Distamycin c-myc mRNA levels in the cell cycle change in mouse erythroleukemia The molecular origin of DNA-drug specificity in netropsin and cells following inducer treatment, 5323 distamycin, 1376 Sequence-specific recognition of B-DNA by oligo(N-methyl- Diffusion pyrrolecarboxamide)s, 2565 The cytoplasmic matrix: Its volume and surface area and the diffusion of molecules through it, 5030 Dbstnce geometry Solution of the embedding problem and decomposition of symmetric a-Difluoromethylornithine matrices, 2197 Prevention of a plant disease by specific inhibition of fungal polyamine biosynthesis, 6874 Disulfide bond A chemically cleavable biotinylated nucleotide: Usefulness in the recovery of protein-DNA complexes from avidin affinity Adhesion to human cells by Escherichia coli lacking the major subunit of columns, 2593 a digalactoside-specific pilus-adhesin, 1800 Disulfide bond formation in the eye lens, 7965 Dihydro4-hydroxy-5-deazaflavin Disulfide bridge Stereochemical studies of a selenium-containing hydrogenase from Radiation inactivation of ricin occurs with transfer of destructive energy Methanococcus vannielii: Determination of the absolute configuration across a disulfide bridge, 5357 of C-5 chirally labeled dihydro-8-hydroxy-5-deazaflavin cofactor, 1364 Dithlothreltol Dihydrofolate reductase The monomeric ad form of the insulin receptor exhibits much higher y-Fluoromethotrexate: Synthesis and biological activity of a potent insulin-dependent tyrosine-specific protein kinase activity than the inhibitor of dihydrofolate reductase with greatly diminished ability to intact aA form of the receptor, 6095 form poly-y-tglutamates, 2598 Limited proteolysis of the bifunctional thymidylate synthase- Divergence dihydrofolate reductase from Leishmania tropica, 7188 Prediction of homology and divergence in the secondary structure of polypeptides, 366 Dihydrofolate reductase gene Ultrastructural features of minute chromosomes in a Divesty region methotrexate-resistant mouse 3T3 cell line, 1126 Possible involvement of human D minigenes in the first Efficient cloning of single-copy genes using specialized cosmid vectors: complementarity-determining region of K light chains, 2125 Isolation of mutant dihydrofolate reductase genes, 1189 Opposite-strand RNAs from the 5' flanking region of the mouse Diversity region gene dihydrofolate reductase gene, 3978 Organization and sequences of the diversity, joining, and constant region Gene amplification: An example of accelerated evolution in tumorigenic genes of the human T-cell receptor , chain, 8624 cells, 7015 DNA activation Dihydropyridine A method for mapping intranuclear protein-DNA interactions and its Long-opening mode of gating of neuronal calcium channels and its application to a nuclease hypersensitive site, 2296 promotion by the dihydropyridine calcium agonist Bay K 8644, 2178 DNA adduct Dihydroxyacetone Distribution of initial and persistent 2-acetylaminofluorene-induced DNA Adrenergic regulation of gluconeogenesis: Possible involvement of two adducts within DNA loops, 6605 mechanisms of signal transduction in a1-adrenergic action, 6727 Detection of benzo[a]pyrene diol epoxide-DNA adducts in peripheral blood lymphocytes and antibodies to the adducts in serum from coke 2,4-Dihydroxyphenylalanlne oven workers, 6672 In vitro studies of 2,4-dihydroxyphenylalanine, a prodrug targeted against malignant melanoma cells, 2960 DNA ageption In vitro studies of 2,4-dihydroxyphenylalanine, a prodrug targeted against Ionic mluibition of formation of RecA nucleoprotein networks blocks malignant melanoma cells (Correction), 6020 homologous pairing, 5646 1,25-Dihydroxyvitamin D3 DNA amplification Cultured psoriatic fibroblasts from involved and uninvolved sites have a Differential amplification, assembly, and relocation of multiple DNA partial but not absolute resistance to the proliferation-inhibition activity sequences in human neuroblastomas and neuroblastoma cell lines, 3761 of 1,25-dihydroxyvitamin D3, 5409 DNA amplification patterns in maize endosperm nuclei during kernel 1,25-Dihydroxyvitamin D3 causes formation of multinucleated cells with development, 7010 several osteoclast characteristics in cultures of primate marrow, 8213 DNA binding protein 1,25-Dih.droxvtamin D3 recptor Interaction of the X site-specific recombination protein Xis with ldentification oftheporcine intestinal 1,25-dihydroxyvitamin D3 receptor attachment site DNA, 1040 on sodium dodecyl sulfate/polyacrylamide gels by renaturation and Deletions within a hinge region of a specific DNA-binding protein, 2301 Identification of a nucleic acid helix-destabilizing protein from rat liver as immunoblotting, 7825 lactate dehydrogenase-5, 5260 dim gene Amino acid sequence of the UP1 calf thymus helix-destabilizing protein Modified cryptochrome in vivo absorption in dim photosporulation and its homology to an analogous protein from mouse myeloma, 5666 mutants of Trichoderma, 2736 Isolation and characterization of the product of the methionine-regulatory gene met! of Escherichia coli K-12, 6104 2,6-Dimethoxy-p-semiquinone Use of a protein-blotting procedure and a specific DNA probe to identify Enzyme-controlled scavenging of ascorbyl and 2,6-dimethoxy- nuclear proteins that recognize the promoter region of the transferrin semiquinone free radicals in Ehrlich ascites tumor cells, 1439 receptor gene, 6741 Dimethyl sulfoxide DNA catenane Maintenance of differentiated rat hepatocytes in primary culture, 3252 Determination of the stereostructure of the product of Tn3 resolvase by a general method, 1079 7,12-Dimethylbenz[a~anthracene Focal smooth muscle proliferation in the aortic intima produced by an DNA, chloroplt initiation-promotion sequence, 3450 Chloroplast DNA diversity is low in a wild plant, Lupinus texensis, 6950 Subject Index Proc. Natl. Acad. Sci. USA 82 (1985) 8869

DNA cleavage, nonenzymatic DNA melting Nonenzymatic sequence-specific cleavage of single-stranded DNA, 963 Base composition-independent hybridization in tetramethylammonium Sequence-specific cleavage of single-stranded DNA: Oligodeoxy- chloride: A method for oligonucleotide screening of highly complex nucleotide-EDTA-Fe(II), 968 gene libraries, 1585 Sequence-specific cleavage of single-stranded DNA: Oligodeoxy- nucleotide-EDTA.Fe(II) (Correction), 3532 DNA nethylation Sequential changes in DNA methylation patterns of the rat DNA deavage, sequence specific phosphoenolpyruvate carboxykinase gene during development, 267 Sequence-specific recognition of B-DNA by oligo(N-methyl- The first intron of the human growth hormone gene contains a binding pyrrolecarboxamide)s, 2565 site for glucocorticoid receptor, 699 DNA cleavage, site-specific Tissue-specific levels of human glucose-6phosphate dehydrogenase Site-specific cleavage of left-handed DNA in pBR322 by correlate with methylation of specific sites at the 3' end of the 6460 gene, 1465 A-tris(diphenylphenanthroline)cobalt(III), Effect of regional DNA methylation of gene expression, 2560 DNA, cruciform Incomplete X chromosome dosage compensation in chorionic villi of Cleavage of cruciform DNA structures by an activity from human placenta, 3390 Saccharomryces cerevisiae, 6445 Specific 57 and 3' regions of the M-chain gene are undermethylated at distinct stages of B-cell differentiation, 3809 DNA damae Nucleotide sequence of the Dpn IIDNA methylase gene of Site-specifically modified oligodeoxyribonucleotides as templates for Streptococcus pneumoniae and its relationship to the dam gene of Escherichia coli DNA polymerase I, 2325 Escherichia coli, 4468 Photoreactivation of UV-induced pyrimidine dimers and erythema in the Perturbation of maintenance and de novo DNA methylation in vitro by marsupial Monodelphis domestica, 2409 UVB (280-340 nm)-induced pyrimidine photodimers, 6055 DNA-damage-inducible (din) loci are transcriptionally activated in Insertion of the bacterial gpt gene into the germ line of mice by retroviral competent Bacillus subtilis, 620i infection, 6927 Modification of chromium (VI)-induced DNA damage by glutathione and One role for DNA methylation in vertebrate cells is strand discrimination cytochrome P450 in chicken embryo hepatocytes, 6755 in mismatch repair, 7350 Cellular and viral DNA hypomethylation associated with induction of DNA-drug binding Epstein-Barr virus lytic cycle, 8090 The molecular origin of DNA-drug specificity in netropsin and DNA methylation at asymmetric sites is associated with numerous distamycin, 1376 transition mutations, 8114 DNA dynamics Insertion of a bacterial gene into the mouse germ line using an infectious Unusual proton exchange properties of Z-form poly[d(G-C)], 1594 retrovirus vector, 8587 DNA-enzyme complex DNA methyltransferase Adenovirus infection elevates levels of cellular topoisomerase I, 2247 Ethylation of poly(dC-dG)*poly(dC-dG) by ethyl methanesulfonate stimulates the activity of mammalian DNA methyltransferase in DNA, extrachromosomal circular vitro, 1045 Li sequences in HeLa extrachromosomal circular DNA: Evidence for Growth-dependent expression of multiple species of DNA circularization by homologous recombination, 1989 methyltransferase in Transposon-like sequences in extrachromosomal circular DNA from murine erythroleukemia cells, 2674 mouse thymocytes, 2072 DNA microinjection DNA frgntation Factors affecting the efficiency of introducing foreign DNA into mice by Lack of lymphocyte-induced DNA fragmentation in human targets during microinjecting eggs, 4438 lysis represents a species-specific difference between human and murine cells, 4482 DNA, mitochondrial Priming of human mitochondrial DNA replication occurs at the d&a" gene light-strand promoter, 351 Characterization of a temperature-sensitive mutant of mouse FM3A cells Initiation of transcription from each of the two human mitochondrial defective in DNA replication, 1761 promoters requires unique nucleotides at the transcriptional start sites, 2660 DNA grase Nucleotide sequence preservation of human mitochondrial DNA, 2895 Mechanism of inhibition of DNA gyrase by analogues of nalidixic acid: Mitochondrial modulation of maternally transmitted antigen: Analysis of The target of the drugs is DNA, 307 cell hybrids, 3286 Mechanisms determining aerobic or anaerobic growth in the facultative Genes for respiratory chain proteins and ribosomal RNAs are present on anaerobe Salmonella typhimurium, 2077 a 16-kilobase-pair DNA species from Chlamydomonas reinhardtii DNA helicase mitochondria, 3340 Effect of DNA polymerase I and DNA helicase II on the turnover rate of UvrABC excision nuclease, 6774 DNA, negatively supercoiled Diethyl pyrocarbonate: A chemical probe for secondary structure in DNA, heterogeneous negatively supercoiled DNA, 8009 Activation of expression of latent Epstein-Barr herpesvirus after gene transfer with a small cloned subfragment of heterogeneous viral DNA, noncodng DNA, 4085 Sex determination: A hypothesis based on noncoding DNA, 1165 DNA, infectious DNA polymerase Infectious hepatis B virus from cloned DNA of known nucleotide A bacteriophage 17 RNA polymerase/promoter system for controlled sequence, 891 exclusive expression of specific genes, 1074 DNA insertion Characterization of a temperature-sensitive mutant of mouse FM3A cells Molecular basis of mutations on the waxy locus of maize: Correlation defective in;DNA replication, 1761 with the fine structure genetic map, 4177 Cell-cycle dependence and properties of the HeLa cell DNA polymerase system, 2220 DNA integration Site-specifically modified oligodeoxyribonucleotides as templates for Homologous recombination between a defective virus and a Escherichia coli DNA polymerase I, 2325 chromosomal sequence in mammalian cells, 3781 Expression in Escherichia coli of a fusion protein product containing a region of the adenovirus DNA polymerase, 2354 DNA inversion The 140-kDA adenovirus DNA polymerase is recognized by antibodies to Site-specific DNA inversion is enhanced by a DNA sequence element in Escherichia coli-synthesized determinants predicted from an open cis, 3776 reading frame on the adenovirus genome, 2652 DNA, kinetoplast Sequence context effects in DNA replication blocks induced by aflatoxin A minimal ribosomal RNA: Sequence and secondary structure of the 9S B1, 3096 kinetoplast ribosomal RNA from Leishmania tarentolae, 1401 Reduced in vivo mutagenesis by mutant herpes simplex DNA polymerase involves improved nucleotide selection, 3889 DNA, left-handed Mouse DNA polymerase a-primase terminates and reinitiates DNA Site-specific cleavage of left-handed DNA in pBR322 by synthesis 2-14 nucleotides upstream of C2A1_2(C2_3/T2) sequences on a A-tris(diphenylphenanthroline)cobalt(III), 6460 minute virus of mice DNA template, 4023 Involvement of helicase II (uvrD gene product) and DNA polymerase I in DNA ligation excision mediated by the uvrABC protein complex, 4925 Cells from an immunodeficient patient (46BR) with a defect in DNA Assignment of the gene for human DNA polymerase a to the X ligation are hypomutable but hypersensitive to the induction of sister chromosome, 5270 chromatid exchanges, 2044 Demonstration of a stimulatory protein for virus-specified DNA DNA, linker polymerase in phorbol ester-treated Epstein-Barr virus-carrying Preferential binding of benzo[ajpyrene diol epoxide to the linker DNA of cells, 5728 human foreskin fibroblasts in S phase in the presence of Replication of phage 429 DNA with purified terminal protein and DNA benzamide, 2769 polymerase: Synthesis of full-length 429 DNA, 6404 Effect of DNA polymerase I and DNA helicase II on the turnover rate of DNA icie UvrABC excision nuclease, 6774 Differential expression of mitochondrial genes between life cycle stages Bacteriophage T7 DNA polymerase: Cloning and high-level of Trypanosoma brucei, 3380 expression, 6783 8870 Subject Index Proc. Natl. Acad. Sci. USA 82 (1985)

DNA polymerase gene DNA, repetitive Sequence and mapping analyses of the herpes simplex virus DNA Tandemly repeated nonribosomal DNA sequences in the chloroplast polymerase gene predict a C-terminal substrate binding domain, 7969 genome of an Acetabularia mediterranea strain, 1706 Li sequences in HeLa extrachromosomal circular DNA: Evidence for DNA polymorphism circularization by homologous recombination, 1989 Analysis of DNA haplotypes suggests a genetic predisposition to trisomy Insertion of long interspersed repeated elements at the Igh 21 associated with DNA sequences on chromosome 21, 3360 (immunoglobulin heavy chain) and Mlvi-2 (Moloney leukemia virus integration 2) loci of rats, 2857 DNA processing Expression of a cytoplasmic LINE-1 transcript is regulated in a human Processing of donor DNA during Haemophilus influenzae transformation: teratocarcinoma cell line, 6050 Analysis using a model plasmid system, 3731 Evolution of apolipoprotein E: Mouse sequence and evidence for an DNA, promiscuous 11-nucleotide ancestral unit, 8085 Ochromonas mitochondria contain a specific chloroplast protein, 1456 DNA replication See also DNA synthesis DNA-protein crosslinking Priming of human mitochondrial DNA replication occurs at the Formaldehyde-mediated DNA-protein crosslinking: A probe for in vivo light-strand promoter, 351 chromatin structures, 6470 Repair of defined single base-pair mismatches in Escherichia coli, 503 Genetic control of chromosome length in yeast, 506 DNA-protein interaction The herpes simplex virus amplicon: Analyses of cis-acting replication A dimer of AraC protein contacts three adjacent major groove regions of functions, 694 the aral DNA site, 3129 Mutations in direct repeat sequences and in a conserved sequence adjacent to the repeats result in a defective replication origin in DNA rearrangement plasmid R6K, 1480 Immunoglobulin JH, C,,, and Cy gene regrrangements in human B Characterization of a temperature-sensitive mutant of mouse FM3A cells lymphocytes clonally transformed by Epstein-Barr virus, 556 defective in DNA replication, 1761 Recombination in mouse L cells between DNA introduced into cells and Characterization of the ColEl primer-RNA1 complex: Analysis of a homologous chromosomal sequences, 1391 domain of ColEl RNA1 necessary for its interaction with primer T-cell receptor gene rearrangements as markers of lineage and clonality RNA, 2257 in T-cell neoplasms, 3460 Replication initiator protein of plasmid R6K autoregulates its own Modification of DNA by glucose 6-phosphate induces DNA synthesis at the transcriptional step, 2574 rearrangements in an Escherichia coli plasmid, 8439 Growth-dependent expression of multiple species of DNA DNA recognition methyltransferase in murine erythroleukemia cells, 2674 Mutational studies with the Initiation of enzymatic replication at the origin of the Escherichia coli trp repressor of Escherichia coli support the chromosome: Contributions of RNA polymerase and primase, 3562 helix-turn-helix model of repressor recognition of operator DNA, 483 An RNA-DNA copolymer whose synthesis is correlated with the DNA, recombinant transcriptional requirement for chromosomal initiation in Bacillus Transfer of genes into hematopoietic cells using recombinant DNA subtilis contains ribosomal RNA sequences, 3586 viruses, 158 Deletion of the terminus region (340 kilobase pairs of DNA) from the chromosome of Escherichia coli, 3766 DNA recombination Initiation of enzymatic replication at the origin of the Escherichia coli A defined system for the DNA strand-transfer reaction at the initiation of chromosome: Primase as the sole priming enzyme, 3954 bacteriophage Mu transposition: Protein and DNA substrate Initiation of DNA replication on single-stranded DNA templates requirements, 7570 catalyzed by purified replication proteins of bacteriophage X and Escherichia coli, 3988 DNA, regulatory In vitro replication of duplex circular DNA containing the simian virus 40 Eukaryotic transient expression system dependent on transcription DNA origin site, 5710 factors and regulatory DNA sequences of vaccinia virus, 19 Replication timing of the H4 histone genes in Physarum potycephalum, 6475 DNA, reiterated Nitrogenase reductase: A functional multigene family in Rhizobium DNA replication block phaseoli, 1170 Sequence context effects in DNA replication blocks induced by aflatoxin B1, 3096 DNA renaturation DNA replication fidelity On the mechanism of renaturation of complementary DNA strands by the A fidelity assay using "dideoxy" DNA sequencing: A measurement of recA protein of Escherichia coli, 297 sequence dependence and frequency of forming 5-bromouracilguanine DNA repair base mispairs, 1301 RAD6 gene of Saccharomyces cerevisiae encodes a protein containing a DNA replication intermediate tract of 13 consecutive aspartates, 168 Accumulation of 10-kilobase DNA replication intermediates in cells Quantitative assessment of the role of 06-methylguanine in the initiation treated with 3-aminobenzamide, 104 of carcinogenesis by methylating agents, 421 Repair of defined single base-pair mismatches in Escherichia coli, 503 DNA, replicative form In situ enzymatic reclosure of opened imidazole rings of purines in DNA Proteins tightly associated with the termini of replicative form DNA of damaged by y-irradiation, 633 Kilham rat virus, an autonomous parvovirus, 8335 Mutagenic DNA repair in Streptomyces, 1180 Cells from an immunodeficient patient (46BR) with a defect in DNA DNA sequence analysis ligation are hypomutable but hypersensitive to the induction of sister Comparative statistics for DNA and protein sequences: Multiple chromatid exchanges, 2044 sequence analysis, 6186 Active site and complete sequence of the suicidal methyltransferase that counters alkylation mutagenesis, 2688 DNA sequence comparison 06-Alkylguanine-DNA alkyltransferase activity correlates with the Comparative statistics for DNA and protein sequences: Single sequence therapeutic response of human rhabdomyosarcoma xenografts to analysis, 5800 1-(2-chloroethyl)-3-(trans-4-methylcyclohexyl)-1-nitrosourea, 2985 Differences in mutagenic and recombinational DNA repair in DNA sequence homology enterobacteria, 4172 Homology requirements for recombination in Escherichia coli, 4768 Mutagenic repair in Escherichia coli: Products of the recA gene and of DNA sequence preservation the umuD and umuC genes act at different steps in UV-induced Nucleotide sequence preservation of human mitochondrial DNA, 2895 mutagenesis, 4193 umuDC and mucAB operons whose products are required for UV light- DNA, single-stranded and chemical-induced mutagenesis: UmuD, MucA, and LexA proteins Nonenzymatic sequence-specific cleavage of single-stranded DNA, 963 share homology, 4331 Sequence-specific cleavage of single-stranded DNA: Oligodeoxy- Inherently radioresistant cells exist in some human tumors, 4732 nucleotide-EDTA*Fe(II), 968 Expression of a cloned denV gene of bacteriophage T4 in Escherichia Sequence-specific cleavage of single-stranded DNA: Oligo- coli, 4763 deoxynucleotide-EDTAFe(II) (Correction), 3532 Possible depletion of a DNA repair enzyme in human lymphoma cells by Initiation of DNA replication on single-stranded DNA templates subversive repair, 5285 catalyzed by purified replication proteins of bacteriophage X and UV-induced mutagenesis of phage S13 can occur in the absence of the Escherichia coli, 3988 RecA and UmuC proteins of Escherichia coli, 6614 Identification of a nucleic acid helix-destabilizing protein from rat liver as One pyrimidine dimer inactivates expression of a transfected gene in lactate dehydrogenase-5, 5260 xeroderma pigmentosum cells, 6622 Amino acid sequence of the UP1 calf thymus helix-destabilizing protein One role for DNA methylation in vertebrate cells is strand discrimination and its homology to an analogous protein from mouse myeloma, 5666 in mismatch repair, 7350 DNA, small polydisperse circular Genetic complementation of UV-induced DNA repair in Chinese hamster Transposon-like sequences in extrachromosomal circular DNA from ovary cells by the denV gene of phage T4, 7656 mouse thymocytes, 2072 Genes from plasmid pKM101 in Haemophilus influenzae: Separation of functions of mucA and mucB, 7753 DNA strand break Repair-defect mutations inhibit rDNA magnification in Drosophila and Endonuclease-resistant apyrimidinic sites formed by neocarzinostatin at discriminate between meiotic and premeiotic magnification, 8095 cytosine residues in DNA: Evidence for a possible role in Exonuclease III recognizes urea residues in oxidized DNA, 8354 mutagenesis, 3182 Subject Index Proc. Natl. Acad. Sci. USA 82 (1985) 8871

The production of DNA strand breaks in human leukocytes by Dog superoxide anion may involve a metabolic process, 6820 Characterization of the enzymatic lesion in inherited phosphofructokinase deficiency in the dog: An animal analogue of human glycogen storage DNA structure disease type VII, 8109 Highly structured sequence homology between an insertion element and Complete nucleotide sequence of dog heart creatine kinase mRNA: the gene in which it resides, 493 Conservation of amino acid sequence within and among species, 8394 The structure of Marek disease virus DNA: The presence of unique expansion in nonpathogenic viral DNA, 751 Dopamine Molecular dynamics simulations of d(C-G-C-G-A)-d(T-C-G-C-G) with and Oxygen chemoreception by carotid body cells in culture, 1448 without "hydrated" counterions, 755 Dopamine decreases conductance of the electrical junctions between The molecular origin of tNA-drug specificity in netropsin and cultured retinal horizontal cells, 3025 distamycin, 1376 Morphology and distribution of tyrosine hydroxylase-like immunoreactive Crystal structure of Z-DNA without an alternating purine-pyrimidine neurons in the cat retina, 6335 sequence, 3611 The structure of Marek disease virus DNA: The presence of unique Dopamine neuron expansion in nonpathogenic viral DNA (Correction), 5236 Parkinsonism-inducing neurotoxin, N-methyl4-phenyl-1,2,3,6- A molecular dynamics simulation of double-helical B-DNA including tetrahydropyridine: Uptake of the metabolite N-methyl- counterions and water, 6537 4-phenylpyridine by dopamine neurons explains selective toxicity, 2173 DNase I-resistant nontranscribed spacer segments of mouse ribosomal Dopamine receptor DNA contain poly(dG-dT)-poly(dA-dC), 7595 Substituted benzamides as ligands for visualization of dopamine receptor Ion etching of bacteriophage T4: Support for a spiral-fold model of in the human brain emission 3863 packaged DNA, 7960 binding by positron tomography, Sequence-dependent energetics of the B-Z transition in supercoiled DNA Dorsal root ganglion containing nonalternating purine-pyrimidine sequences, 8320 Long-opening mode of gating of neuronal calcium channels and its promotion by the dihydropyridine calcium agonist Bay K 8644, 2178 DNA, supercoiled Neuronal traits of clonal cell lines derived by fusion of dorsal root Rapid "footprinting" on supercoiled DNA, 3078 ganglia neurons with neuroblastoma cells, 3499 Torsional stress induces an S1 nuclease-hypersensitive site within the promoter of the Xenopus laevis oocyte-type 5S RNA gene, 4018 Dosage compensation Incomplete X chromosome dosage compensation in chorionic villi of DNA supercoiling human placenta, 3390 Mechanism of inhibition of DNA gyrase by analogues of nalidixic acid: Transformation of salivary gland secretion protein gene Sgs4 in The target of the drugs is DNA, 307 Drosophila: Stage- and tissue-specific regulation, dosage compensation, DNA supercoiling affects in vitro transcription of two maize chloroplast and position effect, 5055 genes differently, 4886 Sequence-dependent energetics of the B-Z transition in supercoiled DNA Dougall expansion containing nonalternating purine-pyrimidine sequences, 8320 Note on four-particle wave functions, 1299 Down syndrome DNA synthesis Analysis of DNA haplotypes suggests a genetic predisposition to trisomy See also DNA replication 21 associated with DNA sequences on chromosome 21, 3360 Cell-cycle dependence and properties of the HeLa cell DNA polymerase core in Alzheimer disease and Down system, 2220 Amyloid plaque protein Negative control for the initiation of meiosis in Schizosaccharomyces syndrome, 4245 pombe, 2447 Dpn II DNA methylase Defective macromolecule biosynthesis and cell-cycle progression in a Nucleotide sequence of the Dpn II DNA methylase gene of mammalian cell starved for mevalonate, 3257 Streptococcus pneumoniae and its relationship to the dam gene of Type P transforming growth factor/growth inhibitor stimulates entry of Escherichia coli, 4468 monolayer cultures of AKR-2B cells into S phase after a prolonged prereplicative interval, 4147 dpnM gene Sequence-dependent termination of in vitro DNA synthesis by cis- and Nucleotide sequence of the Dpn II DNA methylase gene of trans-diamminedichloroplatinum(II), 4616 Streptococcus pneumoniae and its relationship to the dam gene of The regulation of DNA synthesis in quiescent lymphocytes by Escherichia coli, 4468 cytoplasmic inhibitors, 5160 DQ alloantigen DNA topoisomerase Allelie polymorphism and transassociation of molecules encoded by the Phosphorylation of DNA topoisomerase II by casein kinase II: HLA-DQ subregion, 1776 Modulation of eukaryotic topoisomerase II activity in vitro, 3164 DQ a chain gene In situ localization of DNA topoisomerase II, a major polypeptide Nucleotide sequence of an HLA-DQ a chain derived from a DRw9 cell component of the Drosophila nuclear matrix fraction, 4142 line: Genetic and evolutionary implications, 3420 Cloning, characterization, and sequence of the yeast DNA topoisomerase Exuberant restriction fragment length polymorphism associated with the I gene, 4374 a-chain and the DX a-chain 5433 The Escherichia coli supX locus is topA, the structural gene for DNA DQ gene gene, topoisomerase I, 5437 DR13 chain Cloning of yeast TOP), the gene encoding DNA topoisomerase I, and DNA sequence and characterization of human class II major construction of mutants defective in both DNA topoisomerase I and histocompatibility complex P chains from the DR] haplotype, 3405 7178 DNA topoisomerase II, DR3 pseudopene DNA transcription Characterization of an HLA DRg pseudogene, 1475 Actinomycin and DNA transcription, 5328 Drinking DNA, transfected Toward an analogue of alcoholism in mice: Criteria for recognition of Relative rates of homologous and nonhomologous recombination in pharmacologically motivated drinking, 3469 transfected DNA, 3355 Drosophila A human acetylcholinesterase gene identified by homology to the Ace DNA transfection region of Drosophila, 1827 Expression of the metastatic phenotype in cells transfected with human Ancient origin for Hawaiian Drosophilinae inferred from protein metastatic tumor DNA, 1726 comparisons, 4753 Transformation of human cells by DNAs ineffective in transformation of Transcription of Drosophila small hsp-tk hybrid genes is induced by heat NIH 3T3 cells, 2399 shock and by ecdysterone in transfected Drosophila cells, 5865 DNA twist Drosophila melanogaster Nucleosome core particles suppress the thermal untwisting of core DNA Developmental variations in the splicing pattern of transcripts from the and adjacent linker DNA, 4653 Drosophila gene encoding myosin alkali light chain result in different carboxyl-terminal amino acid sequences, 449 DNA virus Superoxide dismutase: An evolutionary puzzle, 824 Transfer of genes into hematopoietic cells using recombinant DNA Sex determination: A hypothesis based on noncoding DNA, 1165 viruses, 158 Independent control elements that determine yolk protein gene expression in alternative Drosophila tissues, 13% DnaB protein Molecular genetics of a transposon-induced dominant mutation in the Specialized nucleoprotein structures at the origin of replication of Drosophila locus Glued, 1751 bacteriophage X: Complexes with X 0 protein and with X 0, X P. and From monoclonal antibody to gene for a neuron-specific glycoprotein in Escherichia coli DnaB proteins, 4678 Drosophila, 1855 Developmental expression of nuclear genes that encode mitochondrial DNase proteins: Insect cytochromes c, 1964 See Deoxyribonuclease Biphasic pattern of histone gene expression during Drosophila oogenesis, 3316 DNase I-hypersensitive site P-element distribution in Eurasian populations of Drosophila The "P-like-globin" gene domain in human erythroid cells, 6384 melanogaster: A genetic and molecular analysis, 5418 F1 and F2: Two similar genes regulated differently during development of DNase protection Drosophila melanogaster, 5795 Rapid "footprinting" on supercoiled DNA, 3078 Genetic dissection of Drosophila adenylate cyclase, 5992 8872 Subject Index Proc. Natl. Acad. Sci. USA 82 (1985)

Structures of defective P transposable elements prevalent in natural Q Egosterol and Q-derived M strains of Drosophila melanogaster, 6236 Sterol control of the phosphatidylethanolamine-phosphatidylcholine Sex- and cell-specific regulation of yolk polypeptide genes introduced conversion in the yeast mutant GL7, 5715 into Drosophila by P-element-mediated gene transfer, 7000 Molecular analysis of the yellow gene (y) region of Drosophila Ehrlich ascites tumor cell melanogaster, 7369 Enzyme-controlled scavenging of ascorbyl and 2,6-dimethoxy- Rapid change in mutation rate in a local population of Drosophila semiquinone free radicals in Ehrlich ascites tumor cells, 1439 melanogaster, 7671 P-element distribution in Eurasian populations of Drosophila The eigenfunction problem in higher dimensions: Asymptotic melanogaster: A genetic and molecular analysis (Correction), 7802 theory, 8275 Repair-defect mutations inhibit rDNA magnification in Drosophila and discriminate between meiotic and premeiotc magnification, 8095 Esentein theorem Transposase titration in Drosophila melanogaster: A model of cytotype Padd and 2212 in the P-M system of hybrid dysgenesis, 8119 approximations diophantine geometry, Identification of a novel receptor in Drosophila for both epidermal EJ gene growth factor and insulin, 8443 Suppression of tumorigenicity in hybrids of normal and Detection of simple polygenic segregations in a natural population, 8552 oncogene-transformed CHEF cells, 2062 Drug binding Elastidty Dissociation from albumin: A potentially rate-limiting step in the Effects of fibrinogen-binding tetrapeptides on mechanical properties of clearance of substances by the liver, 1563 fine fibrin clots, 1410 Drug resistance Electrical fied, radio-frequency Alkylating agent resistance: In vitro studies with human cell lines, 2158 Shape change of sickled erythrocytes induced by pulsed rf electrical Multiply drug-resistant human KB carcinoma cells have decreased fields, 6860 amounts of a 75-kDa and a 72-kDa glycoprotein, 2330 Amplification of DNA sequences in human multidrug-resistant KB Electroconvulslve shock carcinoma cells, 7661 Electroconvulsive shock increases preproenkephalin messenger RNA abundance in rat hypothalamus, 589 Duck Electrogenicity Duck hepatitis B virus DNA in liver and serum of Chinese ducks: Direct measurement of the electrogenic activity of o-type cytochrome Integration of viral DNA in a hepatocellular carcinoma, 5180 oxidase from Escherichia coli reconstituted into planar lipid Duplication, internal bilayers, 2570 Internal duplication and sequence homology in factors V and VIII, 1688 Electron exch e rate Duplication, inverted 1H NMR studies of electron exchange rate of Pseudomonas aeruginosa Isolation of a gene enhancer within an amplified inverted duplication azurin, 2039 after "expression selection", 3370 Electron microscopy DX subregion Structure of the signal recognition particle by electron microscopy, 785 Gene organization of DC and DX subregions of the human major Quantitative structural analysis of eukaryotic ribosomal RNA by histocompatibility complex, 3410 scanning transmission electron microscopy, 5598 Dynein Electron-proton coupling Characterization of monoclonal antibodies against Chlamydomonas Reduction of mammaian ferritin, 3640 flagellar dyneins by high-resolution protein blotting, 4717 Electron spin resonance Spin-label oximetry: Kinetic study of celi respiration using a Dynorphin rapid-passage electron spin resonance display, 411 Sequence and expression of the rat prodynorphin gene, 4291 Tl-sensitive Dyslexia Electron transfer Cortical anomalies in brains of New Zealand mice: A neuropathologic Electrostatic influence on energetics of electron transfer reactions, 3082 model of dyslexia?, 8072 Electron transfer flavoproteln:ubiquinone oxidoreductase Deficiency of electron transfer flavoprotein or electron transfer EIA gene flavoprotein:ubiquinone oxidoreductase in glutaric acidemia type II Mapping of functional domains in adenovirus ElA proteins, 7480 fibroblasts, 4517 A first exon-encoded domain of ElA sufficient for posttranslational modification, nuclear-localization, and induction of adenovirus E3 Electron transport promoter expression in Xenopus oocytes, 8434 Electron transfer-driven ATP synthesis in Methanococcus voltae is not dependent on a proton electrochemical gradient, 6793 Ela region Evidence that a second tumor antigen coded by adenovirus early gene Electronegatvity region Ela is required for efficient cell transformation, 163 Electronegativity and hardness as coordinates in structure stability diagrams, 264 Ear Perpetual production of hair cells and maturational changes in hair cell Eledrophoresis ultrastructure accompany postembryonic growth in an amphibian An electrophoretic karyotype for yeast, 3756 ear, 3911 Electroporation Early transpson Expression of genes transferred into monocot and dicot plant cells by Spatial distribution of transcripts of the long repeated ETn sequence electroporation, 5824 during early mouse embryogenesis, 2054 Electrostatic bond East Coast fever A predicted structure of calmodulin suggests an electrostatic basis for its Identification of a surface antigen on Theileria parva sporozoites by function, 4954 monoclonal antibody, 1771 Electrostatic Interaction Ecdysterone Effect of side chain-backbone electrostatic interactions on the stability of Transcription of Drosophila small hsp-tk hybrid genes is induced by heat a-helices, 5585 shock and by ecdysterone in transfected Drosophila cells, 5865 Elliptocytosis Echinoderm The a-spectrin gene is on chromosome 1 in mouse and man, 3790 Nerves in the spine of a sea urchin: A neglected division of the Elongation complex echinoderm nervous system, 1555 Isolation of stable preinitiation, initiation, and elongation complexes from Economics RNA polymerase II-directed transcription, 2632 Outlining social physics for moderm societies-locating culture, Elongtion factor economics, and politics: The Enlightenment reconsidered, 5582 GTP-binding membrane protein of Escherichia coli with sequence EcolI homology to initiation factor 2 and elongation factors Tu and G, 7500 Regulated expression of endonuclease EcoRI and Saccharomyces Elongation factor Tn cerevisiae: Nuclear entry and biological consequences, 1354 A second tRNA binding site on elongation factor Tu is induced while the factor is bound to the ribosome, 3212 Effector cell Natural effector T lymphocytes in normal mice, 7691 Microtubule distribution in cultured cells and intact tissues: Improved Egg immunolabeling resolution through the use of reversible embedment Multiple polymorphic a- and ,-tubulin mRNAs are present in sea urchin cytochemistry, 6889 eggs, 134 All components required for the eventual activation of muscle-specific Embedding problem actin genes are localized in the subequatorial region of an uncleaved Solution of the embedding problem and decomposition of symmetric amphibian egg, 139 matrices, 2197 Subject Index Proc. Natl. Acad. Sci. USA 82 (1985) 8873

Embryo Endonuclease Si Mouse major histocompatibility class I gene expression begins at DNA from recombinogenic bacteriophages generated by arl mutants of midsomite stage and is inducible in earlier-stage embryos by Escherichia coli is cleaved by single-strand-specific endonuclease 51 interferon, 2427 (Retraction), 953 Cytochrome P-450 metabolic activity in embryonic and extraembryonic tissue lineages of mouse embryos, 3311 Endonuclease V Expression of a cloned denV gene of bacteriophage T4 in Escherichia Embryo development coli, 4763 Quantitative and qualitative changes in histone gene expression during early mouse embryo development, 5685 Endopeptidase Purification of neutral lens endopeptidase: Close similarity to a neutral Embryogenesis proteinase in pituitary, 7545 Injected anti-sense RNAs specifically block messenger RNA translation in vivo, 144 Endopeptidase, neutral Isolation of a cDNA clone for the liver cell adhesion molecule Neutral endopeptidase 24.11 in human neutrophils: Cleavage of (L-CAM), 2809 chemotactic peptide, 8737 Nuclear lamins and peripheral nuclear antigens during fertilization and embryogenesis in mice and sea urchins, 4727 3-Endorphin Cell-type-specific pattern of myc protooncogene expression in developing P-Endorphin: Surface binding and internalization in thymoma cells, 5751 human embryos, 5050 «-Endorphln-(i-27) Expression sequences of cell adhesion molecules, 6942 is a naturally occurring antagonist to Spermidine is bound to a unique protein in early sea urchin ,8Endorphin-(1-27) analgesia, 3178 embryos, 7613 etorphine-induced Expression of the cytokeratin endo A gene during early mouse Endosperm embryogenesis, 8535 DNA amplification patterns in maize endosperm nuclei during kernel development, 7010 Embryonal carcinoma cell Isolation of embryonal carcinoma cell lines that express integrated Endosymbiont recombinant genes flanked by the Moloney murine leukemia virus long Mitochondrial origins, 4443 terminal repeat, 2422 Endothelial cell emm6 gene Activated protein C stimulates the fibrinolytic activity of cultured Relationship of M protein genes in group A streptococci, 1822 endothelial cells and decreases antiactivator activity, 1121 Preferential orientation of centrioles toward the heart in endothelial cells Empirical Bayes estimation, linear of major blood vessels is reestablished after reversal of a Linear empirical Bayes estimation of means and variances, 1571 segment, 3272 Endothelial cells from bovine adrenal medula develop capillary-like Enantiomer growth patterns in culture, 4702 (-)-S-[3H]CGP-12177 and its use to determine the rate constants of Endothelial cells from bovine adrenal medulla develop capillary-like unlabeled A-adrenergic antagonists, 925 growth patterns in culture (Correction), 7474 Encephalomyelitis Human monocyte-endothelial cell interaction in vitro, 8208 Induction of experimental allergic encephalomyelitis in Lewis rats with Endothelial cell growth factor purified synthetic peptides: Delineation of antigenic determinants for Interaction of endothelial cell growth factor with heparin: encephalitogenicity, in vitro activation of cellular transfer, and Characterization and antibody recognition, 6138 proliferation of lymphocytes, 5515 by receptor Prazosin, an a1-adrenergic receptor antagonist, suppresses experimental Endothelium autoimmune encephalomyelitis in the Lewis rat, 5915 An endothelial cell-dependent pathway of coagulation, 2523 The formation of fenestrations and channels by capillary endothelium in Encephalopathy vitro, 6181 Pertussis toxin is required for pertussis vaccine encephalopathy, 8733 Stimulation of the adherence of neutrophils to umbilical vein endothelium 8667 Encephalopathy, spongiform by human recombinant tumor necrosis factor, Transmissible spongiform encephalopathy in the gray tremor mutant Endotoxemia mouse, 253 Protection against Gram-negative bacteremia and endotoxemia with The 200- and 150-kDa neurofilament proteins react with IgG human monoclonalIgM antibodies, 1790 autoantibodies from patients with kuru, Creutzfeldt-Jakob disease, and other neurologic diseases, 3485 Endplate Retrovirus-induced spongiform encephalopathy: The3-end long terminal Myasthenic serum selectively blocks acetylcholine receptors with long repeat-containing viral sequences influence the incidence of the disease channel open times at developing rat endplates, 2533 and the specificity of the neurological syndrome, 8818 Energetics Endo A Electrostatic influence on energetics of electron transfer reactions, 3082 One gene and one pseudogene for the cytokeratin endo A, 1155 Energy coupling Endocytosis Mechanism of inhibition of mitochondrial adenosine triphosphatase by Interferon stimulates cholesterol and phosphatidylcholine synthesis but dicyclohexylcarbodiimide and oligomycin: Relationship to ATP inhibits cholesterol ester synthesis in HeLa-S3 cells, 2417 synthesis, 1589 Murine interferon-a8 receptor-mediated endocytosis and nuclear Energy transduction membrane binding, 3281 Purified hydrophobic proteins, chargerins, are essential for energy Cell-type-specific receptors for a-fetoprotein in a mouse T-lymphoma cell 1331 line, 3301 transduction in oxidative phosphorylation, P-Endorphin: Surface binding and internalization in thymoma cells, 5751 Energy utilization Recycling of epidermal growth factor in a human pancreatic carcinoma Efficiency of utilization of various sources of energy for growth, 4866 cell line, 6172 Tumor necrosis factor: Specific binding and internalization in sensitive Engine, heat and resistant cells, 7626 Nonlinear natural engine: Model for thermodynamic processes in Analysis and isolation of endocytic vesicles by flow cytometry and mesoscale systems, 7805 sorting: Demonstration of three kinetically distinct compartments involved in fluid-phase endocytosis, 8523 EngramBlockade of81- but not ofP2-adrenergic receptors replicates Endocytosis, receptor-mediated propranolol's suppression of the cerebral spread of an engram in Intracellular class II HLA antigens are accessible to transferrin- mice, 7458 neuraminidase conjugates internalized by receptor-mediated Enhancer endocytosis, 8188 Transcription of three c-myc exons is enhanced in chicken bursal Endogenous retrovirus lymphoma cell lines, 53 Friend and Moloney murine leukemia viruses specifically recombine with Structure of the chromosomal gene for murine interleukin 3, 316 different endogenous retroviral sequences to generate mink cell An enhancer-like element in the adenovirus E2 promoter contains focus-forming viruses, 459 sequences essential for uninduced and ElA-induced transcription, 381 Hormonal response region in the mouse mammary tumor virus long Endonuclease terminal repeat can be dissociated from the proviral promoter and has Endonuclease-resistant apyrimidinic sites formed by neocarzinostatin at enhancer properties, 1020 cytosine residues in DNA: Evidence for a possible role in Complete sequence of a gene encoding a human type I keratin: mutagenesis, 3182 Sequences homologous to enhancer elements in the regulatory region The replication initiator protein of plasmid pT181 has sequence-specific of the gene, 1609 endonuclease and topoisomerase-like activities, 6845 Isolation of a gene enhancer within an amplified inverted duplication after "expression selection", 3370 Endonuclease EcoRI Deletion of a B-cell-specific enhancer affects transfected, but not Regulated expression of endonuclease EcoRI and Saccharomyces endogenous, immunoglobulin heavy-chain gene expression, 5088 cerevisiae: Nuclear entry and biological consequences, 1354 Activation regions in a yeast transposon have homology to mating type control sequences and to mammalian enhancers, 5423 Endonuclease I][ Transposable element sequences involved in the enhancement of yeast Endonuclease III (nth) mutants of Escherichia coli, 474 gene expression, 5428 8874 Subject Index Proc. Natl. Acad. Sci. USA 82 (1985)

Efficient insertion of genes into the mouse germ line via retrovial Enzyme reaction vectors, 6148 Alternative view of enzyme reactions, 2225 The "P-like-globin" gene domain in human erythroid cells, 6384 Location of cis-acting regulatory sequences in the human T-cell leukemia Enzyme regulation, pretranatonal virus type I long terminal repeat, 6502 Sex-dependent expression of mouse testosterone 16a-hydroxylase A viral Iong terminal repeat in the interleukin 2 gene of a cell line that (cytochrome P-4501(,,): cDNA cloning and pretranslational constitutively produces interleukin 2, 7284 regulation, 2024 A long and complex enhancer activates transcription of the gene coding Enzyme-RNA complex for the highly abundant immediate early mRNA in murine Covalent enzyme-RNA complex: A tRNA modification that prevents a cytomegalovirus, 8325 covalent interaction also prevents aminoacylation, 339 Upstream promoter element of the human metallothionein-11A gene can enzyme act like an enhancer element, 8572 Enzyme secretion Pertussis toxin inhibits chemotactic peptide-stimulated generation of Etnkephalin inositol phosphates and lysosomal enzyme secretion in human Conformationally restricted analogs of somatostatin with high it-opiate leukemic (HL-60) cells, 3277 receptor specificity, 236 Electroconvulsive shock increases preproenkephalin messenger RNA Eocyte abundance in rat hypothalamus, 589 Eubacteria, halobacteria, and the origin of photosynthesis: The Characterization of [3H][2-D-jenicillamine, 5-D-jenicillamine]enkephalin photocytes, 3716 binding to 8 opiate receptors in the rat brain and neuroblastoma-glioma Eubacterna, halobacteria, and the origin of photosynthesis: The hybrid cell line (NG 108-15), 2543 photocytes (Correction), 7154 Enkephalins have a direct positive inotropic effect on cultured cardiac Epldemioiog myocytes, 5930 Aflatoxin metabolism in humans: Detection of metabolites and nucleic Changes in plasma proenkephalin peptide F and catecholamine levels acid adducts in urine by affinity chromatography, 6492 during graded exercise in men, 6349 Visualization of ; opiate receptors in rat brain by using a computerized Epidermal growth factor autoradiographic subtraction technique, 6667 Chromosomal locations of the human and mouse genes for precursors of Neurokinin B is a preferred agonist for a neuronal substance P receptor epidermal growth factor and the , subunit of nerve growth factor, 469 and its action is antagonized by enkephalin, 7444 Stimulation of glycolysis and amino acid uptake in NRK-49F cells by Expression of preproenkephalin-like mRNA and its peptide products in transforming growth factor , and epidermal growth factor, 1350 mammalian testis and ovary, 7467 Epidermal growth factor precursor is related to the translation product of Depolarization regulates adrenal preproenkephalin mRNA, 8252 the Moloney sarcoma virus oncogene mos, 1921 Role of protein kinase C in diacylglycerol-mediated induction of ornithine Enlighten ent decarboxylase and reduction of epidermal growth factor binding, 1941 Outlining social physics for modern societies-locating culture, Epidermal growth factor stimulates glycogen synthase activity in cultured economics, and politics: The Enlightenment reconsidered, 5582 cells, 4563 Vaccinia virus-infected cells release a novel polypeptide functionally Enolase, neuronspecific related to transforming and epidermal growth factors, 5300 Molecular clomng and the nucleotide sequence of cDNA for Heparin-treated, v-myc-transformed chicken heart mesenchymal cells neuron-specific enolase messenger RNA of rat brain, 7453 assume a normal morphology but are hypersensitive to epidermal Enterobacteria growth factor (EGF) and brain fibroblast growth factor (bFGF); cells Differences in mutagenic and recombinational DNA repair in transformed by the v-Ha-ras oncogene are refractory to EGF and bFGF but are hypersensitive to insulin-like growth factors, 5781 enterobacteria, 4172 Evidence for the involvement of the submandibular gland epidermal Enterotoxin B gene growth factor in mouse mammary tumorigenesis, 5940 Molecular cloning of staphylococcal enterotoxin B gene in Escherichia Recycling of epidermal growth factor in a human pancreatic carcinoma coli and Staphylococcus aureus, 5850 cell line, 6172 Synthesis and secretion of human epidermal growth factor by Escherichia env gene coli, 7212 Genomic diversity of the acquired immune deficiency syndrome virus Sustained release of epidermal growth factor accelerates wound HTLV-III: Different viruses exhibit greatest divergence in their repair, 7340 envelope genes, 4813 Epidermal growth factor regulates the expression of its own receptor, 8374 Environment, complex Stabilized complexes of epidermal growth factor and its receptor on the Evidence for active synapse formation or altered postsynaptic cell surface stimulate RNA synthesis but not mitogenesis, 8513 metabolism in visual cortex of rats reared in complex environments, 4549 Epidermal growth factor receptor Stimulation of giucose uptake by transforming growth factor (3: Evidence Enzyme active site for the requirement of epidermal growth factor-receptor Regeneration of active enzyme by formation of hybrids from inactive activation, 1346 derivatives: Implications for active sites shared between polypeptide Tumor-promoting phorbol diesters cause the phosphorylation of chains of aspartate transcarbamoylase, 361 epidermal growth factor receptors in normal human fibroblasts at Active site structures of deoxyhemerythrin and oxyhemerythrin, 713 threonine-654, 1974 Identification of an active site peptide of skeletal myosin after c-erbB activation in avian leukosis virus-induced erythroblastosis: photoaffinity labeling with N-(4-azido-2-nitrophenyl)-2-aminoethyl Clustered integration sites and the arrangement of provirus in the diphosphate, 1575 c-erbB alleles, 2287 Active site of triosephosphate isomerase: In vitro mutagenesis and Phorbol esters induce transient internalization without degradation of characterization of an altered enzyme, 2272 unoccupied epidermal growth factor receptors, 2774 Argininosuccinate synthetase: Essential role of cysteine and arginine Platelet-derived growth factor mimics phorbol diester action on epidermal residues in relation to structure and mechanism of ATP growth factor receptor phosphorylation at threonine-654, 4080 activation, 6745 Characterization and sequence of the promoter region of the human Active site dynamics of ribonuclease, 8458 epidermal growth factor receptor gene, 4920 for both Enzyme assembly Identification of a novel receptor in Drosophila epidermal Pathway of assembly of ribulosebisphosphate carboxylase/oxygenase growth factor and insulin, 8443 from Anabaena 7120 expressed in Escherichia coli, 6546 Epidermal growth factor receptor gene A v-erbB-related protooncogene, c-erbB-2, is distinct from the Enzyme catalysis c-erbB-1/epidermal growth factor-receptor gene and is amplified in a Enzyme-catalyzed processes in organic solvents, 3192 human salivary gland adenocarcinoma, 6497 Enzyme electrophoresis Epidermis A population genetic framework for the study of invasive diseases caused Structure of a gene for the human epidermal 67-kDa keratin, 1896 by serotype b strains of Haemophilus influenzae, 5078 Cultured psoriatic fibroblasts from involved and uninvolved sites have a Enzyme evolution partial but not absolute resistance to the proliferation-inhibition activity The gene coding for carbamoyl-phosphate synthetase I was formed by of 1,25-dihydroxyvitamin D3, 5409 fusion of an ancestral glutaminase gene and a synthetase gene, 2244 Epilepsy Benzodiazepine/-aminobutyric acid receptor deficit in the midbrain of Enzyme Induction the 6701 Cloning and expression of cDNA for rat heme oxygenase, 7865 seizure-susceptible gerbil, Epithelial cell Enzyme mechanism Induction of transformation and continuous cell lines from normal human Electrostatic influence on energetics of electron transfer reactions, 3082 mammary epithelial cells after exposure to benzo[a]pyrene, 2394 Cryobaroenzymic studies as a tool for investigating activated complexes: Creatine kinase-ADP-Mg-nitrate-creatine as a model, 7495 Epithelial cell, airway Stereochemical course of the reaction catalyzed by the pyridoxal Chloride uptake into cultured airway epithelial cells from cystic fibrosis phosphate-dependent enzyme 1-aminocyclopropane-l-carboxylate patients and normal individuals, 6677 synthase, 7820 Epithelium Enzyme, multifunctional Lens-specific expression of the chloramphenicol acetyltransferase gene Oligomeric structure of the multifunctional protein CAD that initiates promoted by 5' flanking sequences of the murine aA-crystallin gene in pyrimidine biosynthesis in mammalian cells, 6802 explanted chicken lens epithelia, 2334 Subject Index Proc. Natl. Acad. Sci. USA 82 (1985) 8875

Can villin be used to identify malignant and undifferentiated normal 6-Phosphogluconolactonase deficiency, a heredityerythrocyte enzyme digestive epithelial cells?, 8488 deficiency: Possible interaction with glucose-6-phosphate dehydrogenase deficiency, 3876 Epithelium, tight Repetitive A epitope (type 3 chain A) defined by blood group A,-specific Single anion-selective channels in basolateral membrane of a mammalian monoclonal antibody TH-1: Chemical basis of qualitative Aland A2 tiht epithelium, 7791 distinction (Correction), 3948 Visualization of the protein associations in the erythrocyte membrane Epitope skeleton, 6153 Small peptides induce antibodies with a sequence and structural Adenine ribo- and deoxyribonucleotide metabolism in human requirement for binding antigen comparable to antibodies raised against erythrocytes, B- and T-lymphocyte cell lines, and monocyte- the native protein, 178 macrophages, 6682 Bioeffective monoclonal antibody against the decapeptide Activated and unactivated forms of human erythrocyte aldose gonadotropin-releasing hormone: Reacting determinant and action on 7222 ovulation and estrus suppression, 1228 reductase, Identical short peptide sequences in unrelated proteins can have different conformations: A testing ground for theories of immune ds specifically to sulfated glycolipids, 1306 recognition, 5255 ErthroteW deformation Epoxide hydrolase Shape change of sickled erythrocytes induced by pulsed rf electrical Rapid purification of cytosolic epoxide hydrolase from normal and clofibrate-treated animals by affinity chromatography, 1663 Erythrocyte membrane Epoxide, polyunsaturated Detection and characterization of a mouse a-spectrin cDNA clone by its Total synthesis of (+)-lla-hydroxyprogesterone by cyclization of a expression in Escherichia coli, 1367 polyunsaturated epoxide, 1879 Electron microscopic observation of domain movement in reconstituted erythrocyte membranes, 7304

Ehibitors of the cytochrome P-450 enzymes block the Erythrold celi secretagogue-induced release of corticotropin in mouse pituitary tumor Isolation of recombinant cDNAs encoding chicken erythroid cells, 1012 8-aminolevulinate synthase, 3702

EpsteinBarr virus Immunoglobulin JH, C,,r and Cy gene rearrangements in human B kat cells infected with anemia-inducing Friend leukemia virus contain lymphocytes clonally transformed by Epstein-Barr virus, 556 integrated replication-competent but not defective proviral Production of antibody associated with non-A, non-B hepatitis in a genomes, 5925 chimpanzee lymphoblastoid cell line established by in vitro Erythroleukemla cell transformation with Epstein-Barr virus, 2138 Carbonic anhydrase is aberrantly and constitutively expressed in both Expression of a second Epstein-Barr virus-determined nuclear antigen in murine 5175 mouse cells after gene transfer with a cloned fragment of the viral human and erythroleukemia cells, genome, 3435 Erytbromycin resisance Activation of expression of latent Epstein-Barr herpesvirus after gene Eviden-e for functional interaction between domains II and V of 23S transfer with a small cloned subfragment of heterogeneous viral ribosomal RNA from an mutant, 8330 DNA, 4085 erythromycin-resistant Demonstration of a stimulatory protein for virus-specified DNA Ery tborsi polymerase in phorbol ester-treated Epstein-Barr virus-carrying )ntogeny of hamster hemoglobins in yolk-sac erythroid cells in vivo and cells, 5728 in culture, 2794 A third viral nuclear protein in lymphoblasts immortalized by Interleukin 3 promotes erythroid burst formation in "serum-free" cultures Epstein-Barr virus, 5944 without detectable erythropoietin, 3291 Identification and expression of a nuclear antigen from the genomic region of the Jijoye strain of Epstein-Barr virus that is missing in its nonimmortalizing deletion mutant, P3HR-1, 7429 Colony formation by primitive hemopoietic progenitor cells in serum-free Cellular and viral DNA hypomethylation associated with induction of medium, 775 Epstein-Barr virus lytic cycle, 8090 Interleukin 3 promotes erythroid burst formation in "serum-free" cultures without detectable erythropoietin, 3291 EpsteiBarr viru nuclear antigen Expression of a second Epstein-Barr virus-determined nuclear antigen in -xythropoledn gene mouse cells after gene transfer with a cloned fragment of the viral Cloning and expression of the human erythropoietin gene, 7580 genome, 3435 Carboxyl-terminal domain of the Epstein-Barr virus nuclear antigen is Escherlchia coil highly immunogenic in man, 6300 Molybdate reduction by Escherichia coli K-12 and its chl mutants, 227 Analysis of the transcript encoding the latent Epstein-Barr virus nuclear Macrophage activation by monosaccharide precursors of Escherichia coli antigen I: A potentially polycistronic message generated by long-range lipid A, 282 splicing of several exons, 8305 Endonuclease HI (nth) mutants of Escherichia coli, 474 Mutational studies with the trp repressor of Escherichia coli support the EpsenBrr virus receptor helix-turn-helix model of repressor recognition of operator DNA, 483 gpl40, the C3d receptor of human B lymphocytes, is also the Repair of defined single base-pair mismatches in Escherichia coli , 503 Epstein-Banr virus receptor, 1490 Molecular cloning of the gene for the RNA-processing enzyme RNase III of Escherichia coli, 849 erb gmn NZB mouse system for production of monoclonal antibodies to weak Distinctive effects of the viral oncogenes myc, erb, fps, and src on the bacterial antigens: Isolation of an IgG antibody to the polysaccharide differentiation program of quail myogenic cells, 426 capsules of Escherichia coli K1 and group B meningococci, 1194 Chimeric chemosensory transducers of Escherichia coli, 1326 erbB gene Detection and characterization of a mouse a-spectrin cDNA clone by its Epidermal growth factor precursor is related to the translation product of expression in Escherichia coli, 1367 the Moloney sarcoma virus oncogene mos, 1921 Isolation and point of action of a factor from Escherichia coli required to reconstruct translation, 1648 Erythema Protection against Gram-negative bacteremia and endotoxemia with Photoreactivation of UV-induced pyrimidine dimers and erythema in the human monoclonal IgM antibodies, 1790 marsupial Monodelphis domestica, 2409 Adhesion to human cells by Escherichia coli lacking the major subunit of a digalactoside-specific pilus-adhesin, 1800 Expression of ginA in Escherichia coli is regulated at tandem 3C NMR studies of carbon metabolism in the hyphal fungus Aspergillus promoters, 1979 nidulans, 14 Sequences of the active-site peptides of three of the high-M Erythrobastosis penicillin-binding proteins of Escherichia coli K-12, 1999 c-erbB activation in avian leukosis virus-induced erythroblastosis: Chicken triosephosphate isomerase complements an Escherichia coli Clustered integration sites and the arrangement of provirus in the deficiency, 2014 c-erbB alleles, 2287 Expression in Escherichia coli of a fusion protein product containing a region of the adenovirus DNA polymerase, 2354 Ergdrct Expression of Plasmodium falciparum surface antigens in Escherichia MaEmalian reticulocytes lose adhesion to fibronectin during maturation coi, 2518 to erythrocytes, 440 Dual role for Escherichia coli RecA protein in SOS mutagenesis, 3325 Oxidative stress and protective mechanisms in erythrocytes in relation to Molybdate reduction by Escherichia coli K-12 and its chli mutants Plasomodium vinckei load, 548 (Correction), 3532 Cloned cDNA for rabbit erythrocyte carbonic anhydrase I: A novel Chemical synthesis of a gene encoding the human complement fragment erythrocyte-specific probe to study development in erythroid C5a and its expression in Escherichia coli, 3543 tissues, 663 Deletion of the terminus region (340 kilobase pairs of DNA) from the 23Na and 39K NMR studies of ion transport in human erythrocytes, 1099 chromosome of Escherichia coli, 3766 Repetitive A epitope (type 3 chain A) defined by blood group Al-specific Initiation of DNA replication on single-stranded DNA templates monoclonal antibody TH-1: Chemical basis of qualitative Al and A2 catalyzed by purified replication proteins of bacteriophage X and distinction, 1199 Escherichia col, 3988 Membrane knobs are required for the microcirculatory obstruction Cloning and expression of cDNA for salmon growth hormone in induced by Plasmodium falciparum-infected erythrocytes, 3829 Escherichia coli, 4306 8876 Subject Index Proc. Natl. Acad. Sci. USA 82 (1985)

Homology requirements for recombination in Escherichia coli, 4768 Ether stress Multimeric complement component C9 is necessary for killing of Effects of intravenous and intraventricular injection of antisera directed Escherichia coli J5 by terminal attack complex CSb-9, 4808 against corticotropin-releasing factor on the secretion of anterior Penicillin binding proteins: Role in initiation of murein synthesis in 7787 Escherichia coli, 5632 pituitary hormones, Cloning, expression in Escherichia coli, and reconstitution of human Ethidium myoglobin, 5681 Purified hydrophobic proteins, chargerins, are essential for energy An invertible element of DNA controls phase variation of type 1 fimbriae transduction in oxidative phosphorylation, 1331 of Escherichia coli, 5724 Molecular cloning of staphylococcal enterotoxin B gene in Escherichia Ethyl methanesulfonate coli and Staphylococcus aureus, 5850 Ethylation of poly(dC-dG)*poly(dC-dG) by ethyl methanesulfonate Mini-F plasmid-induced SOS signal in Escherichia coli is RecBC stimulates the activity of mammalian DNA methyltransferase in dependent, 5973 vitro, 1045 Chimeric chemosensory transducers of Escherichia coli (Correction), 6019 N-Ethyl-N-nltrosourea Role of the SulB (FtsZ) protein in division inhibition during the SOS Lack of evidence for skeletal abnormalities in offspring of mice exposed response in Escherichia coli: FtsZ stabilizes the inhibitor SulA in to ethylnitrosourea, 2852 maxicells, 6045 A mutation in the 0-globin gene detected in the progeny of a female Cloning and expression in Escherichia coli of the cDNA for murine mouse treated with ethylnitrosourea, 5829 tumor necrosis factor, 6060 Dose-repetition increases the mutagenic effectiveness of Expression and assembly of active cyanobacterial ribulose-1,5- N-ethyl-N-nitrosourea in mouse spermatogonia, 6619 bisphosphate carboxylase/oxygenase in Escherichia coli containing stoichiometric amounts of large and small subunits, 6100 Ethyl retinoate Carboxyl-terminal domain of the Epstein-Barr virus nuclear antigen is Activation of retinoic acid by coenzyme A for the formation of ethyl highly immunogenic in man, 6300 retinoate, 6419 RNase T is responsible for the end-turnover of tRNA in Escherichia coli, 6427 Ethylation Pathway of assembly of ribulosebisphosphate carboxylase/oxygenase Ethylation of poly(dC-dG)-poly(dC-dG) by ethyl methanesulfonate from Anabaena 7120 expressed in Escherichia coli, 6546 stimulates the activity of mammalian DNA methyltransferase in Synthesis and secretion of human epidermal growth factor by Escherichia vitro, 1045 coli, 7212 Ethylenediaminetetraacetic acid Molecular cloning and regulated expression of the human c-myc gene in Nonenzymatic sequence-specific cleavage of single-stranded DNA, 963 Escherichia coli and Saccharomyces cerevisiae: Comparison of the Sequence-specific cleavage of single-stranded DNA: Oligodeoxy- protein products, 7232 nucleotide-EDTA*Fe(II), 968 Oxygen binding properties of human mutant hemoglobins synthesized in Sequence-specific cleavage of single-stranded DNA: Oligo- Escherichia coli, 7252 3532 Genetic manipulation of membrane phospholipid composition in deoxynucleotide-EDTA-Fe(II) (Correction), Escherichia coli: pgsA mutants defective in phosphatidylglycerol N-Ethyhnaleimide synthesis, 7530 Different effects of N-ethylmalemide on Ml and M2 muscarine receptors Transient fluorescence in synchronously dividing Escherichia coli, 7599 in rat brain, 580 Reconstitution of regulatory properties of adenylate cyclase in Escherichia coli extracts, 8300 ETn Human apolipoprotein E expression in Escherichia coli: Structural and Spatial distribution of transcripts of the long repeated ETn sequence functional identity of the bacterially produced protein with plasma during early mouse embryogenesis, 2054 apolipoprotein E, 86% Nonheritable resistance to chloramphenicol and other antibiotics induced Etorphine by salicylates and other chemotactic repellents in Escherichia coli P-Endorphin-(1-27) is a naturally occurring antagonist to K-12, 8771 etorphine-induced analgesia, 3178 Esterase ets gene Kinetic properties of a sex pheromone-degrading enzyme: The sensillar The ets sequence from the transforming gene of avian erythroblastosis esterase of Antheraea polyphemus, 8827 virus, E26, has unique domains on human chromosomes 11 and 21: Both loci are transcriptionally active, Esterase D locus 7294 Assignment of the gene for Wilson disease to chromosome 13: Linkage to Eubacteria the esterase D locus, 1819 Pattern analysis of SS rRNA, 2437 Eubacteria, halobacteria, and the origin of photosynthesis: The Estradiol 16ea-hydroxylation photocytes, 3716 Estradiol 16a-hydroxylation in the mouse correlates with mammary Eubacteria, halobacteria, and the origin of photosynthesis: The tumor incidence and presence of murine mammary tumor virus: A 7154 possible model for the hormonal etiology of breast cancer in photocytes (Correction), humans, 6295 Eukaryotic initiation factor 2 Monoclonal antibodies to an interferon-induced Mr 68,000 protein and Estradlol-receptor complex their use for the detection of double-stranded RNA-dependent protein Specific modulation of the transcription of cloned avian vitellogenin II kinase in human cells, 4341 gene by estradiol-receptor complex in vitro, 988 The 90-kDa component of reticulocyte heme-regulated eIF-2a (initiation factor 2 a-subunit) kinase is derived from the ,B subunit of Estramustine spectrin, 5332 Dansylated estramustine, a fluorescent probe for studies of estramustine uptake and identification of intracellular targets, 8483 Eukaryotic initiation factor 4B receptor Isolation and characterization of factors from wheat germ that exhibit Esbtgen eukaryotic initiation factor 4B activity and overcome Exclusive nuclear location of estrogen receptors in Squalus testis, 1336 7-methylguanosine 5'-triphosphate inhibition of polypeptide Immunocytochemical staining of estrogen receptor in paraffin sections of synthesis, 330 human breast cancer by use of monoclonal antibody: Comparison with that in frozen sections, 4803 Evolution, concerted Cloning of the human estrogen receptor cDNA, 7889 Variances and covariances of identity coefficients of a multigene Estrus suppression family, 829 Bioeffective monoclonal antibody against the decapeptide Evolution, molecular gonadotropin-releasing hormone: Reacting determinant and action on Superoxide dismutase: An evolutionary puzzle, 824 ovulation and estrus suppression, 1228 An unusual genetic code in nuclear genes of Tetrahymena, 2452 Ethanol Evolution, prebiotic Cloning and sequencing of cDNA encoding the complete mouse liver Unidirectional circulation in a prebiotic photochemical 4115 alcohol dehydrogenase, 2262 cycle, Toward an analogue of alcoholism in mice: Criteria for recognition of Evolution rate pharmacologically motivated drinking, 3469 Interaction of selection and biased gene conversion in a multigene Immunochemical evidence for induction of the alcohol-oxidizing family, 153 cytochrome P450 of rabbit liver microsomes by diverse agents: Ethanol, imidazole, trichloroethylene, acetone, pyrazole, and Excision nuclease isoniazid, 4065 Effect of DNA polymerase I and DNA helicase II on the turnover rate of UvrABC excision 6774 Ethanol metabolism nuclease, Cloning of cDNAs for human aldehyde dehydrogenases 1 and 2, 3771 Excitation-contraction coupling A 1H NMR technique for observing metabolite signals in the spectrum of Inositol 1,4,5-trisphosphate: A possible chemical link in perfused liver, 5246 excitation-contraction coupling in muscle, 6352 Ether, diethyl Exercise Evidence for a role of endogenous corticotropin-releasing factor in cold, Changes in plasma proenkephalin peptide F and catecholamine levels ether, immobilization, and traumatic stress, 1247 during graded exercise in men, 6349 Subject Index Proc. Natl. Acad. Sci. USA 82 (1985) 8877

Exocytosis Fabry disease The rate-determining step in cAMP-mediated exocytosis in the rat parotid Fabry disease: Isolation of a cDNA clone encoding human and submandibular glands appears to involve analogous 26-kDa integral a-galactosidase A, 7364 membrane phosphoproteins, 3237 Factor FVYI inhibitor Exon Localization of human factor FVIII inhibitor epitopes to two polypeptide Repeating modular structure of the fibronectin gene: Relationship to fragments, 7728 structure and subunit variation, 6571 protein Factor IX "Exon shuffling' Evidence for a prevalent dimorphism in the activation peptide of human "Exon-shuffiing" maps control of antibody- and T-cell-recognition sites to coagulation factor IX, 2847 the NH2-terminal domain of the class II major histocompatibility Polymorphism of normal factor IX detected by mouse monoclonal polypeptide A , 2940 antibodies, 3839 "Exon-shuffling' maps control of antibody- and T-cell-recognition sites to Immunoaffinity purification of factor IX (Christmas factor) by using the NH2-terminal domain of the class II major histocompatibility conformation-specific antibodies directed against the factor IX-metal polypeptide Al (Correction), 5236 complex, 3879 Expression of hybrid class I genes of the major histocompatibility Factor V complex in mouse L cells, 6245 Internal duplication and sequence homology in factors V and VIII, 1688 Exonuclease Factor VII Cloning of Physarum actin sequences in an exonuclease-deficient Internal duplication and sequence homology in factors V and VIII, 1688 bacterial host, 2698 Purified human factor VIII procoagulant protein: Comparative hemostatic Exonudease HI response after infusions into hemophilic and von Willebrand disease Exonuclease III recognizes urea residues in oxidized DNA, 8354 dogs, 8752 Expanion, DNA Factor X The structure of Marek disease virus DNA: The presence of unique Characterization ofan almost full-length cDNA coding for human blood expansion in nonpathogenic viral DNA, 751 coagulation factor X, 3591 The structure of Marek disease virus DNA: The presence of unique Falciparum iterspersed repeat antigen expansion in nonpathogenic viral DNA (Correction), 5236 Interspersed blocks of repetitive and charged amino acids in a dominant Expression selection immunogen of Plasmodiumfalciparum, 543 Isolation of a gene enhancer within an amplified inverted duplication Fat after "expression selection", 3370 Efficiency of utilization of various sources of energy for growth, 4866 Expression vector Fatty acid Overproduction of the protein product of a nonselected foreign gene Inhibition of human platelet phospholipase A2 activity by unsaturated carried by an adenovirus vector, 3567 fatty acids, 371 Characterization of rate-controlling steps in vivo by use of an adjustable Circulating hydroxy fatty acids in familial Mediterranean fever, 1232 expression vector, 3577 Leukotriene B5 is formed in human neutrophils after dietary Molecular cloning and regulated expression of the human c-myc gene in supplementation with icosapentaenoic acid, 1540 Escherichia coli and Saccharomyces cerevisiae: Comparison of the Abnormal polyunsaturated fatty acid patterns of serum lipids in protein products, 7232 alcoholism and cirrhosis: Arachidonic acid deficiency in cirrhosis, 1815 Expression of biologically active bovine luteinizing hormone in Chinese Acyl-acyl carrier protein as a source of fatty acids for bacterial hamster ovary cells, 7280 bioluminescence, 6085 Human apolipoprotein E expression in Escherichia coli: Structural and functional identity of the bacterially produced protein with plasma Fatty acid binding protein apolipoprotein E, 86% Isolation and partial characterization of a fatty acid binding protein in rat liver plasma membranes, 4 Extensin Isolation and characterization of cDNA clones for carrot extensin and a Faulting proline-rich 33-kDa protein, 4399 Fracture dynamics of fusion of two anti-plane cracks, 1869 Extinction Fecal peilet Bird remains from an archaeological site on Henderson Island, South Pellet microfossils: Possible evidence for metazoan life in Early Pacific: Man-caused extinctions on an "uninhabited" island, 6191 Proterozoic time, 5809 Extraceliular matrix Feedback, ultrashort loop Mammalian reticulocytes lose adhesion to fibronectin during maturation Ultrashort-loop positive feedback of corticotropin (ACTH)-releasing to erythrocytes, 440 factor to enhance ACTH release in stress, 3528 Molecular cloning and sequence analysis of a chondroitin sulfate Feeding behavior proteoglycan cDNA, 1321 Neuropeptide Y injected in the paraventricular hypothalamus: A Laminin is associated with the "neurite outgrowth-promoting factors" powerful stimulant of feeding behavior, 3940 found in conditioned media, 2183 Peptidergic modulation of patterned motor activity in identified neurons Incorporation of cellular and plasma fibronectins into smooth muscle cell of Helisoma, 7140 extracellular matrix in vitro, 2746 Mr 205,000 sulfoglycoprotein in extracellular matrix of mouse fibroblast Fenestration cells is immunologically related to high moecular weight The formation of fenestrations and channels by capillary endothelium in microtubule-associated proteins, 5776 vitro, 6181 Eye Fentanvl Calcium binding in pigmented and albino eyes, 6716 Purification of the opiate receptor of-NG108-15 neuroblastoma-glioma hybrid cells, 4974 Eye lens Opacification of '-tcrystallin solutions from calf lens in relation to cold Feriedoxin cataract formation, 1701 W4Fe-4S]-cluster-depleted Azotobacter vinelandii ferredoxin I: A new 3Fe Lens-specific expression of the chloramphenicol acetyltransferase gene iron-sulfur protein, 5661 promoted by 5' flanking sequences of the murine aA-crystallin gene in Ferredoxin gene explanted chicken lens epithelia, 2334 Cloning and nucleotide sequence determination of the Clostridium Lens-specific expression and developmental regulation of the bacterial pasteurianum ferredoxin gene, 1653 chloramphenicol acetyltransferase gene driven by the murine aA-crystallin promoter in transgenic mice, 7815 Ferritin Disulfide bond formation in the eye lens, 7%5 Structure of human ferritin light subunit messenger RNA: Comparison Purified lens junctional protein forms channels in planar lipid films, 8468 with heavy subunit message and functional implications, 3139 Reduction of mammalian ferritin, 3640 F42 cofactor Stereochemical studies of a selenium-containing hydrogenase from Fertilization Methanococcus vannielii: Determination of the absolute configuration Calcium channel antagonists inhibit the acrosome reaction and bind to of C-5 chirally labeled dihydro-8-hydroxy-5-deazaflavin cofactor, 1364 plasma membranes of sea urchin sperm, 1460 Microtubule configurations during fertilization, mitosis, and early Fl gene development in the mouse and the requirement for egg F) and F2: Two similar genes regulated differently during development of microtubule-mediated motility during mammalian fertilization, 4152 Drosophila melanogaster, 5795 Nuclear lamins and peripheral nuclear antigens during fertilization and embryogenesis in mice and sea urchins, 4727 F plasmid Preferential fertilization in Plumbago: Ultrastructural evidence for Mini-F plasmid-induced SOS signal in Escherichia coli is RecBC gamete-level recognition in an angiosperm, 6129 dependent, 5973 Mobilization of specific maternal RNA species into polysomes after fertilization in Xenopus laevis, 7636 FO protein Studies on the mechanism of oxidative phosphorylation: Effects of a-Fetoprotein specific FO modifiers on ligand-induced conformation changes of Cell-type-specific receptors for a-fetoprotein in a mouse T-lymphoma cell F1, 7550 line, 3301 8878 Subject Index Proc. Natl. Acad. Sci. USA 82 (1985)

Tyrosine sulfation of proteins from the human hepatoma cell line The oncofetal domain of fibronectin defined by monoclonal antibody HepG2, 7160 FDC-6: Its presence in fibronectins from fetal and tumor tissues and its absence in those from normal adult tissues and plasma, 6517 Fo-F1 ATP synthase Tyrosine sulfation of proteins from the human hepatoma cell line Evidence that the Mg-dependent low-affinity binding site for ATP and Pi HepG2, 7160 demonstrated on the isolated f3 subunit of the FoF1 ATP synthase is a catalytic site, 1886 Fibronectin gene Repeating modular structure of the fibronectin gene: Relationship to fgr gene protein structure and subunit variation, 6571 Isolation and chromosomal localization of the human fgr protooncogene, a distinct member of the tyrosine kinase gene family, 6595 Flbrosarcoma Molecular characterization of novel H-2 class I molecules expressed by a Fibril, scrapie-associated C3H UV-induced fibrosarcoma, 5485 Specific proteins associated with Creutzfeldt-Jakob disease and scrapie share antigenic and carbohydrate determinants, 4263 Fibrosarcoma cell Synthesis and secretion of proteins resembling platelet-derived growth Fibrin factor by human glioblastoma and fibrosarcoma cells in culture, 2404 Effects of fibrinogen-binding tetrapeptides on mechanical properties of fine fibrin clots, 1410 Fidelity assay An endothelial cell-dependent pathway of coagulation, 2523 A fidelity assay using "dideoxy" DNA sequencing: A measurement of Discrimination between fibrin and fibrinogen by a monoclonal antibody sequence dependence and frequency of forming 5-bromouracilguanine against a synthetic peptide, 7091 base mispairs, 1301 Fibrinopn Filament, helical Discnmination between fibrin and fibrinogen by a monoclonal antibody Paired helical filaments from Alzheimer disease patients contain against a synthetic peptide, 7091 cytoskeletal components, 3916 Tyrosine sulfation of proteins from the human hepatoma cell line HepG2, 7160 Flanentous bacteriophage Interaction of purified type IIB von Willebrand factor with the platelet Thioredoxin is required for filamentous phage assembly, 29 membrane glycoprotein lb induces fibrinogen binding to the glycoprotein Hb/IIIa complex and initiates aggregation, 7424 Fliopodium The effect of Arg-Gly-Asp-containing peptides on fibrinogen and von Differentiation of neuronal growth cones: Specialization of filopodial tips Willebrand factor binding to platelets, 8057 for adhesive interactions, 8256 Fibrinogen-binding tetrapeptide Fimbria Effects of fibrinogen-binding tetrapeptides on mechanical properties of An invertible element of DNA controls phase variation of type 1 fimbriae fine fibrin clots, 1410 of Escherichia coli, 5724 Fibrinogen gene fip gene Evolution and organization of the fibrinogen locus on chromosome 4: Thioredoxin is required for filamentous phage assembly, 29 Gene duplication accompanied by transposition and inversion, 2344 Firefly Fibrinolysis Characterization of octopamine-sensitive adenylate cyclase: Elucidation Activated protein C stimulates the fibrinolytic activity of cultured of a class of potent and selective octopamine-2 receptor agonists with endothelial cells and decreases antiactivator activity, 1121 toxic effects in insects, 599 Coronary thrombolysis with facilitated absorption of intramuscularly injected tissue-type plasminogen activator, 4258 Fish oil The primary plasminogen-activator inhibitors in endothelial cells, Leukotriene B5 is formed in human neutrophils after dietary platelets, serum, and plasma are immunologically related, 8710 supplementation with icosapentaenoic acid, 1540 Fibroblast Flavin Autoregulation of collagenase production by a protein synthesized and Coding nucleotide sequence of rat NADPH-cytochrome P450 secreted by synovial fibroblasts: Cellular mechanism for control of oxidoreductase cDNA and identification of flavin-binding domains, 973 collagen degradation, 1916 Tumor-promoting phorbol diesters cause the phosphorylation of Fiavodoxin epidermal growth factor receptors in normal human fibroblasts at Coding-nucleotide sequence of rat NADPH-cytochrome P450 threonine-654, 1974 oxidoreductase cDNA and identification of flavin-binding domains, 973 Heat-resistant variants of Chinese hamster fibroblasts altered in Flavoprotein expression of heat shock protein, 8029 Deficiency of electron transfer flavoprotein or electron transfer Type P transforming growth factor controls the adipogenic differentiation flavoprotein:ubiquinone oxidoreductase in glutaric acidemia type II of 3T3 fibroblasts, 8530 fibroblasts, 4517 Fibroblast growth factor Stricture of glycolate oxidase from spinach, 6855 Heparin affinity of anionic and cationic capillary endothelial cell growth factors: Analysis of hypothalamus-derived growth factors and Flounder fibroblast growth factors, 805 Antifreeze protein genes are tandemly linked and clustered in the genome A nonmitogenic pituitary function of fibroblast growth factor: Regulation of the winter flounder, 2613 of thyrotropin and prolactin secretion, 5545 Flow cytometry Fibroblast growth factor, acidic Analysis and isolation-of endocytic vesicles by flow cytometry and Pure brain-derived acidic fibroblast growth factor is a potent angiogenic sorting: Demonstration of three kinetically distinct compartments vascular endothelial cell mitogen with sequence homology to involved in fluid-phase endocytosis, 8523 interleukin 1, 6409 Primary structure of bovine pituitary basic fibroblast growth factor (FGF) Flower petal and comparison with the amino-terminal sequence of bovine brain Flower petal microtexture is a tactile cue for bees, 4750 acidic FGF, 6507 FLP Fibroblast growth factor, basic Two-micrometer circle site-specific recombination: The minimal substrate Primary structure of bovine pituitary basic fibroblast growth factor (FGF) and the possible role of flanking sequences, 5875 and comparison with the amino-terminal sequence of bovine brain The FLP recombinase of the yeast 2-pm plasmid: Characterization of its acidic FGF, 6507 recombination site, 7270 Fibroblast growth factor, brain Fluctuation, orientatbonal Heparin-treated, v-myc-transformed chicken heart mesenchymal cells Fast and slow orientational fluctuations in membranes, 2029 assume a normal morphology but are hypersensitive to epidermal Fluorescein hapten growth factor (EGF) and brain fibroblast growth factor (bFGF); cells Interleukin 1 can act as a B-cell growth and differentiation 8153 transformed by the v-Ha-ras oncogene are refractory to EGF and factor, bFGF but are hypersensitive to insulin-like growth factors, 5781 Fluorescein isothiocyanate-dextran Analysis and isolation of endocytic vesicles by flow cytometry and Fibronectin sorting: Demonstration of three kinetically distinct compartments Isolation of tyrosine-O-sulfate by Pronase hydrolysis from fibronectin involved in fluid-phase 8523 secreted by Fujinami sarcoma virus-infected rat fibroblasts, 34 endocytosis, Mammalian reticulocytes lose adhesion to fibronectip during maturation Fluorescence to erythrocytes, 440 Transient fluorescence in synchronously dividing Escherichia coli, 7599 Laminin binds specifically to sulfated glycolipids, 1306 On the origin of species of fibronectin, 1424 Fluorescence recovery after photobleaching Incorporation of cellular and plasma fibronectins into smooth muscle cell Direct measurement of lateral transport in membranes by using extracellular matrix in vitro, 2746 time-resolved spatial photometry, 4122 Inhibition of platelet aggregation by a monoclonal antibody against human fibronectin, 3844 rFiuoromethotrexate A 125/115-kDA cell surface receptor specific for vitronectin interacts y-Fluoromethotrexate: Synthesis and biological activity of a potent with the arginine-glycine-aspartic acid adhesion sequence derived from inhibitor of dihydrofolate reductase with greatly diminished ability to fibronectin, 5766 form poly-y-glutamates, 2598 Subject Index Proc. Natl. Acad. Sci. USA 82 (1985) 8879 flMet-Leu-Phe Phorbol 12-myristate 13-acetate and insulin increase the concentration of Selective enhancement of the expression of granulocyte functional fructose 2,6-bisphosphate and stimulate glycolysis in chicken embryo antigens 1 and 2 on human neutrophils, 2503 fibroblasts, 6440 Pertussis toxin inhibits fMet-Leu-Phe- but not phorbol ester-stimulated changes in rabbit neutrophils: Role of G proteins in excitation response Fruit fly coupling, 2708 See Drosophila Pertussis toxin inhibits chemotactic peptide-stimulated generation of inositol phosphates and lysosomal enzyme secretion in human Frustration leukemic (HL-60) cells, 3277 A model of protein conformational substates, 3670 fMet-Leu-Phe receptor Jiz gene Association of the N-formyl-Met-Leu-Phe receptor in human neutrophils "Frizzy" genes of Myxococcus xanthus are involved in control of with a GTP-binding protein sensitive to pertussis toxin, 869 frequency of reversal of gliding motility, 8767 FtsZ protein Folic acid Role of the SulB (FtsZ) protein in division inhibition during the SOS Inhibition of phosphoribosylaminoimidazolecarboxamide transformylase response in Escherichia coli: FtsZ stabilizes the inhibitor SuLA in by methotrexate and dihydrofolic acid polyglutamates, 4881 maxicells, 6045 Follicle Fucose Formation of a transformed follicle is necessary but not sufficient for Fucose-containing glycolipids are stage- and region-specific antigens in development of an avian leukosis virus-induced lymphoma, 213 developing embryonic brain of rodents, 3045 Follile-stimulating hormone Isolation and partial characterization of a M, 32,000 protein with inhibin a-L-Fucosidase activity from porcine follicular fluid, 7217 Molecular cloning of a cDNA for human a-L-fucosidase, 1262 Inhibition of gonadotropin-induced granulosa cell differentiation by Fuel, finite activation of protein kinase C, 8518 Probabilistic aspects of finite-fuel stochastic control, 5579 Follitropin release Fujinami sarcoma virus Human seminal a inhibins: Isolation, characterization, and Isolation of tyrosine-O-sulfate by Pronase hydrolysis from fibronectin structure, 4041 secreted by Fujinami sarcoma virus-infected rat fibroblasts, 34 Foot-and-mouth disease virus Fukui function Small peptides induce antibodies with a sequence and structural Hardness, softness, and the fukui function in the electronic theory of requirement for binding antigen comparable to antibodies raised against metals and catalysis, 6723 the native protein, 178 Sequence variation in the gene for the immunogenic capsid protein VP1 Function, linked of foot-and-mouth disease virus type A, 2618 Application of the principle of linked functions to ATP-driven ion pumps: Kinetics of activation by ATP, 3658 "Footprinting"' Rapid "footprinting" on supercoiled DNA, 3078 Fusion, cell Correlation between fusion and the developmental regulation of Formaldehyde membrane glycoproteins in L6 myoblasts, 8409 Formaldehyde-mediated DNA-protein crosslinking: A probe for in vivo chromatin structures, 6470 Fusion protein Expression in Escherichia coli of a fusion protein product containing a Forinamidopyrimidine region of the adenovirus DNA polymerase, 2354 In situ enzymatic reclosure of opened imidazole rings of purines in DNA Fusions of secreted proteins to alkaline phosphatase: An approach for damaged by -irradiation, 633 studying protein secretion, 5107 Formate Expression at the cell surface of biologically active fusion and Role of hepatic tetrahydrofolate in the species difference in methanol hemagglutinin/neuraminidase proteins of the paramyxovirus simian toxicity, 3854 virus 5 from cloned cDNA, 7520 Chloride/formate exchange with formic acid recycling: A mechanism of Futile cycle active chloride transport across epithelial membranes, 6362 Increased activity of the glucose cycle in the liver: Early characteristic of Forskolin -type 2 diabetes, 2965 Catalytic unit of adenylate cyclase: Purification and identification by G gene affinity crosslinking, 3086 uvrA and recA mutations inhibit a site-specific transition produced by a fos gene single 06-methylguanine in gene G of bacteriophage 4X174, 7173 Removal of a 67-base-pair sequence in the noncoding region of Gl phase protooncogene fos converts it to a transforming gene, 4987 Kinetic analysis of regulatory events in G1 leading to proliferation or Induction of the proto-oncogenefos by nerve growth factor, 7330 quiescence of Swiss 3T3 cells, 5365 fps gene GABA Distinctive effects of the viral oncogenes myc, erb, fps, and src on the See -y-Aminobutyric acid differentiation program of quail myogenic cells, 426 gag-pol gene fps/fes gene Murine leukemia virus protease is encoded by the gag-pol gene and is Specific expression of the human cellularfps/fes-encoded protein NCP92 synthesized through suppression of an amber termination codon, 1618 in normal and leukemic myeloid cells, 2379 Gag protein p24 Fracture dynamirs Immunological properties of the Gag protein p24 of the acquired Fracture dynamics of fusion of two anti-plane cracks, 1869 immunodeficiency syndrome retrovirus (human T-cell leukemia virus Fragment gene type HI), 3481 Alternative splicing patterns in an aberrantly rearranged immunoglobulin GAL4 gene K-light-cham gene, 4045 Specific protein binding to far upstream activating sequences in Free energy polymerase II promoters, 43 Stochastic free energy transduction, 3222 Galactosamine oligosaccharide Experimental resolution of cooperative free energies for the ten ligation Complete amino acid sequence of human hemopexin, the heme-binding states of human hemoglobin, 5347 protein of serum, 73 Free radical Galactose-terminated protein Enzyme-controlled scavenging of ascorbyl and 2,6-dimethoxy- An alternative route of infection for viruses: Entry by means of the semiquinone free radicals in Ehrlich ascites tumor cells, 1439 asialoglycoprotein receptor of a Sendai virus mutant lacking its Friend erythroleukemia cell attachment protein, 978 Generation of a dominant 8-MDa deletion at the left terminus of vaccinia a-Galactosidase A virus DNA, 3365 Fabry disease: Isolation of a cDNA clone encoding human a-galactosidase A, 7364 Friend erythroleukemia virus Induction of the early stages of Friend erythroleukemia with helper-free (3-Galatsdase fusion protein Friend spleen focus-forming virus, 6913 Expression in Escherichia coli of a cloned DNA sequence encoding the pre-S2 region of hepatitis B virus, 7540 Friend leukemia virus, anemia-inducing Rat cells infected with anemia-inducing Friend leukemia virus contain Galatosyltransferase integrated replication-competent but not defective proviral Localization of galactosyl- and sialyltransferase by immunofluorescence: genomes, 5925 Evidence for different sites, 4736 Fructose 2,6-bisphosphate -radiation Inhibition by 2,5-anhydromannitol of glycolysis in isolated rat In situ enzymatic reclosure of opened imidazole rings of purines in DNA hepatocytes and in Ehrlich ascites cells, 78 damaged by y-irradiation, 633 8880 Subject Index Proc. Natl. Acad. Sci. USA 82 (1985)

Ganglion, basal Gene deletion The neostriatal mosaic: Compartmental distribution of calcium-binding B cells that simultaneously express surface IgM and IgE in protein and parvalbumin in the basal ganglia of the rat and Nippostrongylus brasiliensis-infected SJA/9 mice do not provide monkey, 8780 evidence for isotype switching without gene deletion, 511 Ganglion cell Gene duplication Two distinct Ca-dependent K currents in bullfrog sympathetic ganglion Complete amino acid sequence of human hemopexin, the heme-binding cells, 3040 protein of serum, 73 Comparative analysis of repeated sequences in rat apolipoproteins A-I, Ganglion, sensory A-IV, and E, 992 Differentiation of catecholaminergic cells in cultures of embryonic avian Two alkaline phosphatase genes positioned in tandem in Bacillus sensory ganglia, 8800 lichentformis MC14 require different RNA polymerase holoenzymes for transcription, 1035 Ganglioside Multiple duplications of complement C4 gene correlate with Mouse monoclonal IgG3 antibody detecting GD3 ganglioside: A phase I H-2-controlled testosterone-independent expression of its sex-limited trial in patients with malignant melanoma, 1242 isoform, C4-Slp, 1746 Laminin binds specifically to sulfated glycolipids, 1306 Periodicity of leucine and tandem repetition of a 24-amino acid segment Strong antitumor activities of IgG3 antibodies to a human in the primary structure of leucine-rich arglycoprotein of human melanoma-associated ganglioside, 1499 serum, 1906 Monoclonal antibody 18B8 detects gangliosides associated with neuronal Evolution and organization of the fibrinogen locus on chromosome 4: differentiation and synapse formation, 4008 Gene duplication accompanied by transposition and inversion, 2344 Disialoganglioside GD3 on human melanoma serves as a relevant target Organization of the human transferrin gene: Direct evidence that it antigen for monoclonal antibody-mediated tumor cytolysis, 5155 originated by gene duplication, 3149 Gap junction Close linkage of a and 8 interferons and infrequent duplication of 8 Reduction of gap junctional conductance by microinjection of antibodies interferon in humans, 4473 against the 27-kDa liver gap junction polypeptide, 2412 Linkage map of three HLA-DR P-chain genes: Evidence for a recent Potential role of the src gene product in inhibition of gap-junctional duplication event, 7197 communication in NIH/3T3 cells, 5360 Human group-specific component (Gc) is a member of the albumin family, 7994 Gas phase reaction Evolution of apolipoprotein E: Mouse sequence and evidence for an Alternative view of enzyme reactions, 2225 11-nucleotide ancestral unit, 8085 Gastrin-releasing peptide Gene evolution High-affinity receptors for peptides of the bombesin family in Swiss 3T3 Evolution and organization of the fibrinogen locus on chromosome 4: cells, 7616 Gene duplication accompanied by transposition and inversion, 2344 Remarkable homology among the internal repeats of erythroid and Gastrula nonerythroid spectrin, 5671 Epidermal keratin gene expressed in embryos of Xenopus laevis, 5413 Structure of the human phosphoglycerate kinase gene and the Gaucher disease intron-mediated evolution and dispersal of the nucleotide-binding Heterogeneity in type I Gaucher disease demonstrated by restriction domain, 6965 mapping of the gene, 5442 Gene expression Gene mapping and leader polypeptide sequence of human A bacteriophage T7 RNA polymerase/promoter system for controlled glucocerebrosidase: Implications for Gaucher disease, 7101 exclusive expression of specific genes, 1074 Molecular cloning and nucleotide sequence of human glucocerebrosidase An adenovirus vector system used to express polyoma virus tumor cDNA, 7289 antigens, 1359 Gemlnivirus Cloning, nucleotide sequence, and overexpression of the bacteriophage Nucleotide sequence of bean golden mosaic virus and a model for gene T4 regA gene, 1901 regulation in geminiviruses, 3572 Expression of a mouse long terminal repeat is cell cycle-linked, 1946 Alternative RNA processing events in human calcitonin/calcitonin Gene amplificatin gene-related peptide gene expression, 1994 Major deletions in the gene encoding the p53 tumor antigen cause lack of Common haplotype dependency of high Gglobin gene expression and p53 expression in HL-60 cells, 790 high Hb F levels in P-thalassemia and sickle cell anemia patients, 2111 Ultrastructural features of minute chromosomes in a Effect of regional DNA methylation of gene expression, 256) methotrexate-resistant mouse 3T3 cell line, 1126 Nucleotide sequence of a yeast Ty element: Evidence for an unusual Isolation of a gene enhancer within an amplified inverted duplication mechanism of gene expression, 2829 after "expression selection", 3370 Isolation of a gene enhancer within an amplified inverted duplication N-myc amplification in multiple homogeneously staining regions in two after "expression selection", 3370 human neuroblastomas, 3736 Altered gene expression during cold acclimation of spinach, 3673 Frequency of molecular alterations affecting ras protooncogenes in Cell-cycle-specific genes differentially expressed in human human urinary tract tumors, 3849 leukemias, 4463 Evolutionary amplification of a pseudogene, 4182 Gene expression and cAMP, 4606 Is the 5S RNA a primitive ribosomal RNA sequence?, 5608 Expression of enzymatically active reverse transcriptase in Escherichia Molecular cloning of rat brain Na,K-ATPase a-subunit cDNA, 6357 coli, 4944 Gene amplification: An example of accelerated evolution in tumorigenic cells, 7015 Gene expression, albumin Amplification of DNA sequences in human multidrug-resistant KB Expression of the mouse serum albumin gene introduced into carcinoma cells, 7661 differentiated and dedifferentiated rat hepatoma cells, 765 Repair-defect mutations inhibit rDNA magnification in Drosophila and Gene expression, collagen discriminate between meiotic and premeiotic magnification, 8095 Altered steady-state ratio of type I/ITT procollagen mRNAs correlates Gene, chemically synthesized with selectively increased type I procollagen biosynthesis in cultured Chemical synthesis of a gene encoding the human complement fragment keloid fibroblasts, 5935 C5a and its expression in Escherichia coli, 3543 Gene expression, constitutive Gene conversion Point mutation generates constitutive expression of an inducible Interaction of selection and biased gene conversion in a multigene eukaryotic gene, 643 family, 153 Variances and covariances of identity coefficients of a multigene Gene expression, coordinated family, 829 Genes selectively expressed in proliferating Dictyostelium amoebae, 8540 Possible involvement of human D minigenes in the first Gene expression, developmental complementarity-determining region of K light chains, 2125 mRNA stabilization controls the expression of a class of developmentally Silkmoth chorion gene families contain patchwork patterns of sequence regulated genes in Dictyostelium discoideum, 5786 homology, 2814 F) and F2: Two similar genes regulated differently during development of Evidence that polymorphism in the murine major histocompatibility 5795 complex may be generated by the assortment of subgene Drosophila melanogaster, sequences, 2890 Gene expression, foreign High-frequency meiotic gene conversion between repeated genes on Expression of phaseolin cDNA genes in yeast under control of natural nonhomologous chromosomes in yeast, 3350 plant DNA sequences, 334 Sequence and evolution of the human T-cell antigen receptor ,-chain Developmentally regulated expression of the bean P-phaseolin gene in genes, 5068 tobacco seed, 3320 Intron sequences reveal evolutionary relationships among major histocompatibility complex class I genes, 5860 Gene expression, globin Structural analysis of an HLA-B27 functional variant: Identification of Adult and fetal human globin genes are expressed following chromosomal residues that contribute to the specificity of recognition by cytolytic T transfer into MEL cells, 780 lymphocytes, 7394 Gene expression during terminal differentiation: Dexamethasone suppression of inducer-mediated a,- and 8"Ki-globin gene Gene-culture coevolution expression, 5020 Color categorization: A possible concordance between genes and culture, 5805 Gene expression, heterologous Gene-culture coevolution: Models for the evolution of altruism with Expression of a functional human insulin receptor from a cloned cDNA cultural transmission, 5814 in Chinese hamster ovary cells, 8014