8TH INTERNATIONAL CONGRESS OF PARKINSON’S DISEASE AND MOVEMENT DISORDERS CONGRESS OF PARKINSON’S DISEASE 8TH INTERNATIONAL TABLE OF CONTENTS Invitation . .2 Acknowledgements . .4 Organization . .5 MDS Committees and Task Forces . .8 International Congress Registration and Venue . 11 International Congress Information . .12 Continuing Medical Education . .12 Evaluations . .12 Press Room . .13 Social Events . .14 Program at a Glance . .17 Scientific Sessions . .18 Faculty . .38 Committee and Task Force Meetings . .41 Exhibitor Information and Directory . .42 Floor Plan and Meeting Space . .46 Map of Rome . .51 Poster Session 1 . .52 Poster Session 2 . .63 Poster Session 3 . .73 Poster Session 4 . .83 THE CONGRESS IS UNDER THE AUSPICES OF: The President of the Italian Republic The Prime Minister of the Italian government The National Institute of Health (ISS) The National Research Council (CNR) The City of Rome The School of Medicine and Surgery, University of Rome “La Sapienza” The Italian Society of Neurology 1 THE MOVEMENT DISORDER SOCIETY INVITATION Dear Colleagues, Rome, Italy On behalf of the Officers and International Executive Committee of The Movement Disorder Society, welcome to the 8th International Congress of Parkinson’s Disease and Movement Disorders. I would like to thank the faculty and the members of the Congress Scientific Program Committee for this exemplary scientific program and for their contribution to the International Congress. The International Congress week begins with a variety of Kickoff Seminars, which are supported through unrestricted educational grants from industry. The week continues with a wide array of plenary sessions, parallel sessions, seminars and video dinners. Poster sessions are unopposed and, to further serve our participants, time has also been allotted for 16 poster platform presentations. I would like to thank the International Congress Oversight Committee and the Congress Organizing Committee for all of their hard work over the past two years. Their dedication in planning has allowed us to offer International Congress attendees the best that Rome has to offer. The social program will include a Sunday Opening Ceremony which will be held on the roof top terrace of the Palazzo dei Congressi. This event offers attendees the opportunity to greet each other while taking in the exquisite tastes and talents of Italy. The Congress Gala Event takes place at the Palazzo Brancaccio, offering a mix of Roman Patrician architecture, as well as enchanting gardens. In closing, I would like to thank all of the International Congress attendees for their participation in the success of the 8th International Congress. Sincerely, C. Warren Olanow President 2 8TH INTERNATIONAL CONGRESS OF PARKINSON’S DISEASE AND MOVEMENT DISORDERS CONGRESS OF PARKINSON’S DISEASE 8TH INTERNATIONAL INVITATION Dear Colleagues, It is my pleasure to welcome you to the 8th International Congress of Parkinson’s Disease and Move- ment Disorders. As one of the world’s most beautiful cities, Rome is an ideal venue for the Interna- tional Congress and I hope that you will enjoy all that the city has to offer. The photograph on the front page shows the Statue of the Nile, part of the Fountain of the Rivers created in 1651 by Gian Lorenzo Bernini and commissioned by Pope Innocenzo X. The Fountain is located in the middle of Piazza Navona and is one of the finest symbols of Baroque art. Its importance lies in the way the sculptor has fused figures, statues, landscapes, and water into one of his most imposing creations. The mass of rocks and grottoes forming the fountain is surmounted by a tall obelisk. At the four corners are colossal figures of the rivers Danube, Ganges, Nile and Plate, repre- senting the four quarters of the globe. With this symbolism in mind, I welcome participants from all over the world. The aim of the Interna- tional Congress is to increase our knowledge in the field of Movement Disorders by sharing global research and perspectives. In line with MDS tradition, the scientific program is informative, compre- hensive and innovative, including plenary session lectures, parallel sessions, platform presentations, abstract poster presentations, seminars and video dinners. On behalf of the Congress Organizing Committee and The Movement Disorder Society, welcome to Rome. Professor Alfredo Berardelli Chair, Congress Organizing Committee 3 THE MOVEMENT DISORDER SOCIETY ACKNOWLEDGEMENTS The Movement Disorder Society wishes to acknowledge and thank the following companies for their support: DOUBLE PLATINUM LEVEL Rome, Italy PLATINUM PLUS LEVEL PLATINUM LEVEL GOLD LEVEL BRONZE LEVEL 4 8TH INTERNATIONAL CONGRESS OF PARKINSON’S DISEASE AND MOVEMENT DISORDERS CONGRESS OF PARKINSON’S DISEASE 8TH INTERNATIONAL ORGANIZATION The Movement Disorder Society (MDS) is an international, PURPOSE, MISSION AND GOALS professional society of clinicians, scientists, and other Purpose: healthcare professionals, who are interested in Parkinson’s The object and mission of the Society shall be to advance the disease, related neurodegenerative and neurodevelopmental neurological sciences pertaining to Movement Disorders; to disorders, hyperkinetic Movement Disorders, and abnormali- operate exclusively for scientific, scholarly and educational ties in muscle tone and motor control. The spectrum of clinical purposes; to encourage research; to provide forums, such as disorders represented by the Society includes but is not medical journals, scientific symposia and International limited to: Congresses, for sharing ideas and for advancing the related Ataxia clinical and scientific disciplines; to encourage interest and Blepharospasm participation in the activities of the Society among healthcare Dysphonia and allied professionals and scientists; and to collaborate with Dystonic disorders other related professional and lay organizations. Gait disorders Huntington’s disease Mission and Goals: Myoclonus To disseminate knowledge about Movement Disorders by: Parkinson’s disease • Providing educational programs for clinicians, scientists Spasticity and the general public designed to advance scientific and Tardive dyskinesia clinical knowledge about Movement Disorders Tics and Tourette syndrome • Sponsoring congresses and symposia on Movement Tremor Disorders The Movement Disorder Society (MDS) was founded in 1985 • Collaborating with other international organizations and on the initiative of Professors Stanley Fahn and C. David lay groups Marsden, whose leadership and vision guided the expansion • Publishing journals, videotapes and other collateral of clinical expertise and research in this field. The organiza- materials committed to high scientific standards and peer tion merged in 1988 with the International Medical Society review for Motor Disturbances. To promote research into causes, prevention and treatment of Movement Disorders by: • Using the Society’s influence and resources to enhance support for research • Facilitating the dissemination of information about research • Encouraging the training of basic and clinical scientists in Movement Disorders and related disorders To formulate and promote public policy that will favorably affect the care of patients with Movement Disorders by: • Working with regulatory agencies to assist them in the approval process of safe and effective therapeutic interven- tions • Informing the public (media) and patient support groups of new research and therapeutic advances • Playing a proactive role in the development of policies that affect support of research and patient care • Developing standards of training in the specialty 5 THE MOVEMENT DISORDER SOCIETY ORGANIZATION MDS OFFICERS Congress Organizing Committee President Chair: Alfredo Berardelli, Italy C. Warren Olanow, USA Giovanni Abbruzzese, Italy Alberto Albanese, Italy President-Elect Paolo Barone, Italy Andrew J. Lees, United Kingdom Ubaldo Bonuccelli, Italy Carlo Colosimo, Italy Secretary Rome, Italy Giovanni Fabbrini, Italy Andres M. Lozano, Canada Mario Manfredi, Italy Stefano Ruggieri Italy Secretary-Elect Fabrizio Stocchi, Italy Philip D. Thompson, Australia Mario Zappia, Italy Treasurer Past Presidents Wolfgang H. Oertel, Germany 2001-2002 Werner Poewe, Austria Treasurer-Elect 1999-2000 Mark Hallett, USA Daniel Tarsy, USA 1997-1998 Eduardo Tolosa, Spain 1995-1996 Joseph Jankovic, USA Past President 1991-1994 C. David Marsden, United Kingdom Werner Poewe, Austria 1988-1991 Stanley Fahn, USA International Executive Committee International Medical Society for Motor Paul J. Bédard, Canada Disturbances Francisco Cardoso, Brazil Past Presidents Cynthia L. Comella, USA 1993-1994 C. Warren Olanow, USA Santiago Giménez-Roldán, Spain 1991-1992 Bastian Conrad, Germany Nir Giladi, Israel 1989-1990 Mark Hallett, USA Ann M. Graybiel, USA 1987-1988 Mario Manfredi, Italy Yoshikuni Mizuno, Japan 1985-1986 C. David Marsden, United Kingdom Kapil D. Sethi, USA Caroline M. Tanner, USA MDS International Secretariat Marie Vidailhet, France The Movement Disorder Society 555 East Wells Street, 11th Floor International Congress Oversight Committee Milwaukee, WI 53202-3823 Chair: Mark Hallett, USA USA Wolfgang H. Oertel, Germany Tel: +1 414-276-2145 C. Warren Olanow, USA Fax: +1 414-276-3349 Werner Poewe, Austria E-mail: [email protected] Eduardo Tolosa, Spain Web site: www.movementdisorders.org Congress Scientific Program Committee ARISTEA - Local Organizing Secretariat Chair: C. Warren Olanow, USA Via Tolmino, 5 - 00198 Rome, Italy Co-Chair 2004: Anthony H.V.