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published by srl • Via Mario Donati, 6 • 20146 Milano (Italy) NEWS ARISTA INDUSTRIES NEWS Arista Industries offers Omega-3 fatty acids, which are necessary for maintaining overall heart health and general wellness. It has been said that Omega-3 Oils help improve cardiovascular health and reduce the risk of heart disease and stroke, help lower triglyceride levels and reduce cholesterol. Arista offers various potencies of Omega-3 Fish Oil from Sardine and Anchovy as well Salmon, Tuna and Krill. The NEWS Omega-3 Vegetable Oils offered include Flax Seed, Perilla, Chia Seed, Sacha Inchi, Rose Hip Seed and Hemp Seed Oils. BIO-GEN EXTRACTS PVT. LTD Bio-gen Extracts Pvt. Ltd, established in the year 2000, is a GMP Certified, Bulk Actives & Nutraceuticals manufacturing company. The company inaugurated its EU GMP Compliant Manufacturing Unit last year. Bio-gen’s strong products are NEWS KAPPA BIOSCIENCE AS Glucosamine, Lycopene, Lutein, Beta Carotene, Soy Isoflavones, Citrus Kappa Bioscience AS is the innovative leader and Bioflavonoids, Green Tea Ext. first mover with its patent protected, high purity etc. ® all-trans vitamin K2 as menaquinone-7 (MK-7). We deliver our vitamin K2, branded as K2VITAL on various commercially suitable carriers, such as NEWS MCC, MCT & microencapsulated powder. Driven by our core vision to make Vitamin K2 MK-7 available for everyone, we own and manage the whole value chain – from production to sales. NEPTUNE TECHNOLOGIES & BIORESSOURCES Neptune Technologies & Bioressources is the NEWS first company to have developed, researched for almost two decades, and commercialized krill oil in the Healthcare industry, creating the NKO® Brand (Neptune Krill Oil™), considered as the Original Krill Oil. NKO® is the highest quality krill oil on the market, due to its superior specifications and is certified by Friend of the Sea for its sustainable harvest. CONTENTS Direttore Responsabile (Editor) Franca Leone Mori [email protected] Direttore Generale / General Manager Michaela (Micky) Carmagnola [email protected] Promozioni / Sales Maurizio Bozzoli [email protected] Marco [email protected] Care for the Abbonamenti / Subscriptions & Accounts 2 Stefania cardiovascular system [email protected] Ruedi Duss B5 srl via Mario Donati, 6 - 20146 Milano - Italy Tel. 0039.02.83241119 Fax 0039.02.8376457 5 Vitamin K2 – Important E-mails for preventing calcification advertising - [email protected] of heart and blood vessels articles - [email protected] press releases - [email protected] subscription - [email protected] Mona Møller other requests - [email protected] Web site www.b5srl.com 14 A review of the evidence for Pacific Deep Ocean Minerals as a new All right reserved to B5 srl. No part of this publication may be complimentary dietary reproduced, stored in a retrieval system or transmitted in any form therapy for the prevention or by any means: electronic, mechanical, photocopy, recording, or otherwise without the prior permission of the publisher B5 srl. and treatment of Fatigue, CVD and Metabolic Syndrome Special regulation for the authors: upon acceptance of an article by the journal, the author/s will be asked to transfer copyright of the article to the publisher. This transfer will ensure the widest possible Anthony P. Jacobs dissemination of information. The ideas expressed in the journal Kevin HU are those of the authors and not those of the publisher. DTP: com3orlando - Milano Photo © 123RF Stock Photo: Pogonici - Coliap | Fotolia: Fabio Berti Care for the cardiovascular system RUEDI DUSS DSM Nutritional Products PO Box 2676, Building 241 4002 Basel, Switzerland The heart is a powerful and vital organ, which will beat more than three billion times over an average lifetime. However, it is susceptible to a number of threats, including coronary heart disease, arterial disease and hypertension, all of which can be referred to as cardiovascular disease (CVD). As the cause of more than 23% of deaths across the world (1) and costing over $ 500 billion globally (2), CVD is a prevalent health problem, which has risen to the forefront of consumer concerns in recent years. THE ART OF A HEALTHY HEART Functional foods and dietary supplements are constantly being developed and launched to meet rising Consumers worldwide increasingly understand that it is consumer demand for heart health benefit solutions. With essential to maintain a healthy heart to reduce the risk of the global market for heart health positioned products developing cardiovascular disease. As well as taking regular growing each year, ingredients suppliers such as DSM are exercise and eating a varied and nutritious diet, consumers continuing to invest in ingredient innovation to help their are now looking to supplement their diets with vitamins customers differentiate their offering in the market. and functional foods and beverages to support their heart health. In the US alone, $ 811.6 million was spent on cardiovascular products in national supermarkets and other HEART HEALTH: OAT SO SERIOUS outlets between August 2012 and August 2013 (3). These developments in consumer behavior are indicative Among the most innovative of recent developments is oat of the emergence of a more holistic and health-focused beta-glucan. A natural component found in oats, oat beta- approach to lifestyle and diet. Indeed, the global heart health glucan has been proven to provide benefits for the heart, as market is expanding, with $ 15.2 billion worldwide sales well as blood sugar management and the digestive system. forecasted to be reached by 2018. Regionally speaking, Multiple clinical studies have reported that the 3 g market development in North America and Europe is recommended daily consumption of beta-glucan can continuing to grow exponentially. Asia-Pacific is now also reduce CVD risk by up to 20%, as it prevents the stomach a promising market, with a compound annual growth rate and intestines from absorbing cholesterol from food. In (CAGR) of approximately support of this claim, the European Food Safety Authority 15% through to 2018 (EFSA) issued a positive opinion substantiating the link expected (4). between beta-glucan intake and reduced blood cholesterol levels. The European Commission then converted this opinion into a fully-substantiated health claim. EFSA has also issued a positive opinion on a claim linking beta-glucan intake to the maintenance of healthy blood glucose. If unmanaged, blood sugar levels can lead to serious forms of diabetes and the associated cardiovascular risks. When oat beta-glucan in the soluble dietary fibers of the oats is digested, it creates a gel which helps the contents of the stomach and the small intestine become more viscous. As a result, the rate at which food is digested and the carbohydrates being absorbed into the bloodstream slows down, which prevents sudden fluctuations in blood sugar levels. 2 A recent addition to DSM’s ‘Guard your heart’ heart health portfolio, DSM’s OatWell® oat beta-glucan provides a range of benefits to both manufacturers and consumers. A natural ingredient, OatWell® is also highly versatile and can be used in a wide variety of applications, including foods, beverages and dietary supplements. This allows manufacturers to position themselves flexibly in the market to the ever more health conscious consumer. CLEARING A PATH FOR HEALTHY CIRCULATION Another notable innovation within the heart health market is DSM’s Fruitflow®. The scientifically-substantiated and award-winning product Fruitflow® is a naturally-derived technology, which helps maintain healthy circulation. This is a key factor for good heart health, as it deters from a FISHING FOR HEART HEALTH SOLUTIONS range of cardiovascular events including blood clots and heart attacks. Fruitflow® does this by combating blood Omega-3s are also an important solution for supporting platelet aggregation to in effect help the blood flow more the cardiovascular system, amongst other health benefits. smoothly. The first ingredient to be approved by EFSA with As a result, production and sales of omega-3 products an Article 13.5 health claim, Fruitflow® has also received have been high and it has been estimated that, in 2013, regulatory approval in the US, where it has GRAS status. global production of omega-3s was at 2.49 million metric Indeed, clinical studies have shown that Fruitflow® reduces tons and valued at $ 4.5 billion (6). platelet aggregation in up to 97% of individuals within The science behind omega-3s is substantial and a 1.5 hours of consumption. When consumed on a regular number of randomized and observational clinical trials basis, the effects last for a full 24 hours (5). show omega-3 consumption lessens the development Licensed exclusively to DSM, Fruitflow® is now of cardiovascular illnesses. Omega-3s are considered as present in a number of successful dietary supplement an effective treatment for reducing the blood pressure products, such as the convenient OptiFlow® liquid of hypertensive patients and helping to avoid the risk capsules marketed by Bricker Labs to the US market. of sudden cardiac death. The most common omega-3 In order to offer consumers natural support for healthy fatty acids are: DHA (docosahexaenoic acid) and EPA heart circulation, European companies have also featured (eicosapentaenoic acid) – both thought to be the most Fruitflow® in dietary supplements, including Healthspan’s beneficial to health – and ALA (alpha-linolenic acid). The Circulease™. American Health Association (AHA) now recommends a daily intake of 0.5-1 g per day of EPA and DHA to lower elevated triglyceride levels in patients. 3 DSM’s portfolio of omega-3s includes life’sOMEGA™, a vegetarian form of DHA and EPA, life’sDHA™, a vegetarian form of DHA derived purely from algae and MEG-3® EPA/ DHA from fish, that deliver all the health benefits with a neutral taste. Omega-3s can be applied to a wide range of products in the food, beverage and dietary supplements market, such as fruit-based drinks, cereal bars, dairy and dairy free products.