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W ith the abbreviation of Asian Journal of Andrology—"AJA" being the basic design element, a strong masculine body structure is created by traditional Chinese calligraphy. The man covering the blue globe symbolizes the consistent tenet of AJA—“Located in Asia, Facing the World.” Asian Journal of Andrology, with this fresh image, is determined to create a brand new chapter in the history of international andrological research, to improve men’s health and to promote scientific communication and cooperation among scientists and doctors in Asia, as well as in the world! With your contributions AJA is certain to stride forward in the following decades! Offi cial journal of the Asian Society of Andrology Visit the Nature Publishing Group booth to receive your complimentary journal samples. Limited - time special offer Featured Collection: Spanning the scope of andrology www.nature.com/aja/focus/featured_collection/index.html Take advantage of FREE online access to select articles for a limited time. 21301-06_AJA 3APFA_10thAnniv RJFP.indd 1 13/8/09 14:29:04 Asian Journal of Andrology Volume 11, Number 5 (Supplement) October 2009 The Proceedings of the Third Asia-Pacifi c Forum on Andrology 10–13 October 2009, Nanjing, China Environment, Life Style & Genetic/Epigenetic Factors and Men’s Health 2009, AJA, SIMM & SJTU. All rights reserved 1008-682X/09 1 2009年增刊 出版许可证（2009）第093号 Contents Welcome Message from Chairman of 3APFA 4 Welcome Message from Chairman of Local Committee of 3APFA 5 Organizations 6 Short CV of Keynote Speakers 8 Agenda 13 Programme 15 Plenary/Symposium Lectures & Oral Presentations/Special Session for Chinese 25 Oral Presentation Poster Presentaion 96 Author Index 173 Instruction for Authors of Asian Journal of Andrology 180 The Third Asia-Pacific Forum on Andrology October 10–13, Nanjing, China npg nature publishing group Asian Journal of Andrology Volume 11, Issue 5, Supplement, October 2009, Published on October 1, 2009 Honorary Editors-in-Chief Deputy Editor-in-Chief Ji-Chuan Zhu, China Rong-Rong Ma, China Shao-Zhen Qian, China David J Handelsman, Australia Dan-Qing Ren, China Jie-Ping Wu, China Editorial Director Hui Zhang, China Associate Editors-in-Chief Qin-Zhu Zheng, China Editor-in-Chief Sujoy K Guha, India Executive Editor for this issue Yi-Fei Wang, China Je Jong Kim, Korea Science Editors Hui Zhang, China Akihiko Okuyama, Japan Ling-Yan Ji, China REGIONAL J Anton Grootegoed, Netherlands Yi-Qun Gu, China Yuan-Chang Yan, China COORDINATORS Zhi-Ping Gu, China Gerhard Haidl, Germany Zheng-Wei Yang, China Ying-Lu Guo, China Aucky Hinting, Indonesia Ching-Hei Yeung, Germany Asia Wayne JG Hellstrom, USA Russell Campbell Jones, Australia Premendu P Mathur, India Barry Hinton, USA Sae Chul Kim, Korea CORRESPONDING EDITORS Ilpo Huhtaniemi, Finland Dolores J Lamb, USA BOARD Australia Yu Jiang, China Will M Lee, Hongkong, China Salman Azhar, USA De-Yi Liu, Australia Niels Jorgensen, Denmark Ching-Shwun Lin, USA Elias Castanas, Greece F-M Köhn, Germany Alvin Y Liu, USA Adel Hassan Elbeheiry, Egypt Africa Iwan Lewis-Jones, UK Peter Yiwen Liu, Australia Paolo Emiliozzi, Italy Ralf Henkel, South Africa Bruno Lunenfeld, Israel Yi-Xun Liu, China Tibet Erdogru, Turkey Soon Chye Ng, Singapore Tom Futai Lue, USA Jiao-Ti Huang, USA Europe Marie-Claire Orgebin-Crist, USA Kamal Zaki Mahmoud, Egypt Yu-Feng Huang, China Louis Gooren, The Netherlands Wolf-Bernhard Schill, Germany William J Moorman, USA Zheng Li, China Roger Short, Australia Toshiaki Noce, Japan Hui Jiang, China North America Ronald S Swerdloff, USA Jae-Seung Paick, Korea Young Chan Kim, Korea Chawnshang Chang, USA Fred C W Wu, UK Gedalia Paz, Israel Shahriar Koochekpour, USA She-Pu Xue, China Gail S Prins, USA Sang Kon Lee, Korea ADVISORY BOARD Brian Peter Setchell, Australia Somboon Leungwattanakij, Thailand EDITORIAL BOARD Jia-Hao Sha, China N K Lohiya, India Chairmen P Ganesan Adaikan, Singapore David Sokal, USA Nian-Qing Lu, China David de Kretser, Australia FX Arif Adimoelja, Indonesia Guang-Huan Sun, Taiwan, China Okabe Masaru, Japan Yong-Lian Zhang, China Ashok Agarwal, USA Qing-Yuan Sun, China Moira Kathleen O’ Bryan, Australia R John Aitken, Australia M Ismail M Tambi, Malaysia Steven M Schrader, USA Members Anna-Maria Andersson, Denmark Hui Meng Tan, Malaysia Zhou-Jun Shen, China Dimitri A Adamopoulos, Greece Susan H Benoff, USA Goh Hng Hang Victor, USA Teruaki Iwamoto, Japan Gordon Baker, Australia Joseph C Cappelleri, USA Guo-Min Wang, China Run Wang, USA Arnold M Belker, USA Wai-Yee Chan, USA Yi-Xin Wang, China Zhong-Cheng Xin, China Hector Chemes, Argentina Junichi Fujii, Japan Patrick YD Wong, Hongkong, China Yuan-Cheng Xu, China Trevor G Cooper, Germany Robert Howard Getzenberg, USA Shu-Jie Xia, China Bo Yang, China Rune Eliasson, Sweden David John Grignon, USA Hong Xiao, China Aleksander Giwercman, Sweden Sidney Ray Grimes, USA Chen Xu, China Sponsored by the Shanghai Institute of Materia Medica (SIMM), Chinese Academy of Sciences and Shanghai Jiao Tong University (SJTU). Granted by Publishing Foundation of Chinese Academy of Sciences, and National Natural Science Foundation of China (NSFC). Supervised by Chinese Academy of Sciences. Published jointly by the Editorial Office, Asian Journal of Andrology and Nature Publishing Group. Printed by Shanghai Tu-Yu Printing House, 28 Lane 23 Yin-Gao Road, Shanghai 200439, China. Edited by the Editorial Office, Asian Journal of Andrology, Room 302, Building 16, 294 Tai-Yuan Rd, Shanghai 200031, China. E-mail: [email protected]; Tel: +86-21-5492-2824; Fax: +86-21-5492-2825. Disclaimer The Publisher, Society and Editors cannot be held responsible for errors or any consequences arising from the use of information contained in this journal; the views and opinions expressed do not necessarily reflect those of the Publisher, Society and Editors, neither does the publication of advertisements constitute any endorsement by the Publisher, Society and Editors of the products advertised. Copyright © 2009 Asian Journal of Andrology, SIMM and SJTU. ISSN 1008-682X EISSN 1745-7262 CN 31-1795/R All rights of reproduction are reserved in respect of all papers, articles, illustrations, etc., published in this journal in all countries of the world. All material published in this journal is protected by copyright, which covers exclusive rights to reproduce and distribute the material. No material published in this journal may be reproduced or stored on microfilm or in electronic, optical or magnetic form without the written authorization of the publisher. Authorization to photocopy material for internal or personal use, or internal or personal use of specific clients, is granted by Nature Publishing Group, to libraries and others registered with the Copyright Clearance Center (CCC) Transaction Reporting Service, provided the relevant copyright fee is paid directly to CCC, 222 Rosewood Drive, Danvers, MA 01923, USA. Identification Code for AJA: 1008-682X/09. Apart from any fair dealing for the purposes of research and private study, or criticism or review, as permitted under the Copyright, Designs and Patent Act 1988, this publication may be reproduced, stored or transmitted, in any form or by any means, only with the prior permission in writing of the publishers, or in the case of reprographic reproduction, in accordance with the terms of the licenses issued by the Copyright Licensing Agency. 国内外公开发行 CN 31-1795/R 邮发代号 4-648 广告经营许可证 3101520090003 国内定价 100.00元 4 Welcome Message from Chairman of 3APFA Dear Colleagues, On behalf of the Asian Journal of Andrology (AJA) and the Organizing Committee, I wish to extend to everyone with great concerns about men's health my cordial invitation to attend the Third Asia-Pacific Forum on Andrology (3APFA), in conjunction with the Tenth Anniversary Celebration of AJA, to be held on October 10–13, 2009, Nanjing, China. The theme of this Forum is “Environment, Life Style & Genetic/Epigenetic Factors and Men's Health”, endeavoring to explore the profundity and diversity of the contributing factors to men's health. The Scientific Committee, under the guidance of the Advisory Committee, designed a comprehensive scientific programme concentrating on one vital issue and embracing a large range of important aspects including: 1 Men's Health: Global and Regional Perspectives 2 Sperm Biology and Fertilization 3 Male Infertility and Assisted Reproductive Technology 4 Male Sexual Dysfunction 5 Male Ageing, Androgen Deficiency and Therapy 6 Prostate Diseases and Prevention, Diagnosis & Treatment of Prostate Cancer 7 Environment Hazards to Men's Health 8 Prevention of Life-threatening STDs/HIV Infections 9 Prevention of Overpopulation and Male Contraception 10 Alternative/Traditional Medicine and Andrology With an aim of bridging the communication between the lab and the clinic, we deeply believe that the Forum deserves the attention from not only basic scientists but also clinicians in the field of andrology. Besides the traditional plenary lectures and symposia we have innovatively introduced in the programme "Panel Discussion on Holistic Concept on Men's Health, Health Determinants and Health Promotion" and "Public Consultation" sessions. "Panel Discussion" session allows an all-dimensional discussion among scientists, clinic doctors, public, media, and policy makers. "Public Consultation" session brings doctors out of the clinics to the public hall and allows the public to touch more knowledge on men's health in a relaxed and friendly atmosphere. In its Tenth Anniversary Celebration, AJA will express a great deal of gratitude to people who support and contribute to its development in various ways, and will review the past, summarize the present and shape the future. In addition, there are several satellite workshops with topics on male infertility, erectile dysfunction, prostate disease, andrology in ARTs, LOH, etc. A specific session for WHO standard semen analysis manual (5th edition) will also be organized during the Forum. We look forward to welcoming you to the 3APFA, Nanjing, China, which no doubt will be a memorable occasion for fruitful interchanges of ideas and the development of long-lasting friendship in the coming years.

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